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MSFIEKVRKLRGAAATMPRRLAIAAVGASLLSGVAVAAGGSPVAGAFSKPGLPVEYLEVPSPSMGRNIKV QFQGGGPHAVYLLDGLRAQDDYNGWDINTPAFEEFYQSGLSVIMPVGGQSSFYSNWYQPSSGNGQNYTYK WETFLTQEMPLWMQSNKQVSPAGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPSEGWWPTLIGL AMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVANNTRIWVYCGNGTPSDLGGDNVPAKFLEGLTLRT NEQFQNNYAAAGGRNGVFNFPANGTHSWPYWNQQLMAMKPDMQQVLLSGNTTAAPAQPAQPAQPAQPAQP AQPAT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5183 | - | - | 100% (355) | antigen 85-C |
| M. avium 104 | MAV_0214 | - | e-131 | 66.27% (335) | antigen 85-A |
| M. avium 104 | MAV_2816 | - | e-121 | 66.45% (310) | antigen 85-B |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0134c | fbpC | 1e-175 | 83.78% (339) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. gilvum PYR-GCK | Mflv_3335 | - | 1e-143 | 72.76% (323) | putative esterase |
| M. tuberculosis H37Rv | Rv0129c | fbpC | 1e-175 | 83.78% (339) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. leprae Br4923 | MLBr_02655 | fbpC2 | 1e-169 | 81.08% (333) | secreted antigen 85A, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_1579 | - | 1e-110 | 55.82% (335) | antigen 85-B precursor |
| M. marinum M | MMAR_0328 | fbpC | 1e-174 | 81.48% (351) | secreted antigen 85-C FbpC |
| M. smegmatis MC2 155 | MSMEG_3580 | - | 1e-141 | 71.73% (329) | antigen 85-C |
| M. thermoresistible (build 8) | TH_2078 | fbpA | 1e-132 | 69.00% (329) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_4793 | fbpC | 1e-175 | 81.48% (351) | secreted antigen 85-C FbpC |
| M. vanbaalenii PYR-1 | Mvan_3061 | - | 1e-142 | 73.37% (323) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3335|M.gilvum_PYR-GCK MKWKEKARG---TRKSLVRRVAAAALAAAALPGLIGVAGGSATAGAFSRP
Mvan_3061|M.vanbaalenii_PYR-1 MKLKEKWRG---TARAAMRRVAAAALAAVALPGLIGFAGGSATAGAFSRP
MSMEG_3580|M.smegmatis_MC2_155 MRGIAAWK--------ALRRFVIGALAALMLPGLIGFAGGSASAGAFSRP
Mb0134c|M.bovis_AF2122/97 MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATAGAFSRP
Rv0129c|M.tuberculosis_H37Rv MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATAGAFSRP
MMAR_0328|M.marinum_M MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAATAGAFSRP
MUL_4793|M.ulcerans_Agy99 MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAATAGAFSRP
MAV_5183|M.avium_104 MSFIEKVRKLRGAAATMPRRLAIAAVGASLLSGVAVAAGGSPVAGAFSKP
MLBr_02655|M.leprae_Br4923 MKFLQQMRKLFGLAAKFPARLTIAVIGTALLAGLVGVVGDTAIAVAFSKP
TH_2078|M.thermoresistible__bu MKLVAKLR---GAARALPRRLTVAALAAALLPGLVGAFGGSATAGAFSRP
MAB_1579|M.abscessus_ATCC_1997 MEFLQKMRG------ATARLAAVAAVAAAILPGLIGVTGGSAIAGAFSRP
* : . ..:.: : *: *... * ***:*
Mflv_3335|M.gilvum_PYR-GCK GLPVEYLDVFSPSMNRDIRIQFQGGG--PHAVYLLDGLRAQEDYNGWDIN
Mvan_3061|M.vanbaalenii_PYR-1 GLPVEYLDVFSPSMGRDIRVQFQGGG--PRAVYLLDGLRAQEDYNGWDIN
MSMEG_3580|M.smegmatis_MC2_155 GLPVEYLDVFSPSMNRDIRVQFQGGG--PHAVYLLDGLRAQDDYNGWDIN
Mb0134c|M.bovis_AF2122/97 GLPVEYLQVPSASMGRDIKVQFQGGG--PHAVYLLDGLRAQDDYNGWDIN
Rv0129c|M.tuberculosis_H37Rv GLPVEYLQVPSASMGRDIKVQFQGGG--PHAVYLLDGLRAQDDYNGWDIN
MMAR_0328|M.marinum_M GLPVEYLQIPSAAMGRDIKVQFQGGG--AHSVYLLDGLRAQDDYNGWDIN
MUL_4793|M.ulcerans_Agy99 GLPVEYLQIPSAAMGRDIKVQFQGGG--AHSVYLLDGLRAQDDYNGWDIN
MAV_5183|M.avium_104 GLPVEYLEVPSPSMGRNIKVQFQGGG--PHAVYLLDGLRAQDDYNGWDIN
MLBr_02655|M.leprae_Br4923 GLPVEYLQVPSPSMGHDIKIQFQGGG--QHAVYLLDGLRAQEDYNGWDIN
TH_2078|M.thermoresistible__bu GLPVEYLMVPSAAMGRDIKVQFQSGGEGSPGVYLLDGLRARDDFNGWDIE
MAB_1579|M.abscessus_ATCC_1997 GLPVEYLQVPSPAMGRDIVVEFQPGG--PHAVYLLDGQRAREDYNGWDIE
******* : *.:*.::* ::** ** .****** **::*:*****:
Mflv_3335|M.gilvum_PYR-GCK TPAFEWFYQSGLSTIMPVGGQSSFYSDWYQPSRGNGQNYTYKWETFLTQE
Mvan_3061|M.vanbaalenii_PYR-1 TPAFEWFYQSGLSTIMPVGGQSSFYTDWYQPSRGNGQNYTYKWETFLSQE
MSMEG_3580|M.smegmatis_MC2_155 TPAFEWFYQSGLSTIMPVGGQSSFYTDWYQPSKGNGQDYTYKWETFLTQE
Mb0134c|M.bovis_AF2122/97 TPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTRE
Rv0129c|M.tuberculosis_H37Rv TPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTRE
MMAR_0328|M.marinum_M TPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTRE
MUL_4793|M.ulcerans_Agy99 TPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTRE
MAV_5183|M.avium_104 TPAFEEFYQSGLSVIMPVGGQSSFYSNWYQPSSGNGQNYTYKWETFLTQE
MLBr_02655|M.leprae_Br4923 TPAFEEYYHSGLSVIMPVGGQSSFYSNWYQPSQGNGQHYTYKWETFLTQE
TH_2078|M.thermoresistible__bu TAAFEWYYESGLSVIMPVGGQSSFYSDWYSPACGNNGCQTYKWETFLTQE
MAB_1579|M.abscessus_ATCC_1997 TTAFEDYYQSGISVVMPVGGQSSNYTDWYNPAKGKDGVWTYKWETFLTTE
*.*** :*.**:*.:******** *::**.*: .:. ********: *
Mflv_3335|M.gilvum_PYR-GCK LPAWLEANRGVSRTGNAVVGLSMAGSASLTYAIHHPQQFIYAASLSGFLN
Mvan_3061|M.vanbaalenii_PYR-1 LPAWLEANRGVSRTGNAVVGLSMAGSAALTYAIYHPQQFIYAASLSGFLN
MSMEG_3580|M.smegmatis_MC2_155 LPAWLEANRGVSRTGNAVVGLSMAGSAALTYAIYHPEQFIYASTLSGFLN
Mb0134c|M.bovis_AF2122/97 MPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLN
Rv0129c|M.tuberculosis_H37Rv MPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLN
MMAR_0328|M.marinum_M MPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFLN
MUL_4793|M.ulcerans_Agy99 MPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFLN
MAV_5183|M.avium_104 MPLWMQSNKQVSPAGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLN
MLBr_02655|M.leprae_Br4923 MPSWLQANKNVLPTGNAAVGLSMSGSSALILASYYPQQFPYAASLSGFLN
TH_2078|M.thermoresistible__bu LPAYLASNYGVDRNRNAAVGLSMAGSAALVLAIYYPQQFQYAASLSGFLN
MAB_1579|M.abscessus_ATCC_1997 LPQWLGVNKGISPAANAVVGLSMAGPSALTLAIYHPQQFVYAGALSAPLH
:* :: * : **.*****:* ::* * ::*:** **.:**. *:
Mflv_3335|M.gilvum_PYR-GCK PSEGWWPMLIGLAMNDAGGFNAESMWGPSSDP--AWKRNDPMVNINQLVA
Mvan_3061|M.vanbaalenii_PYR-1 PSEGWWPMLIGLAMNDAGGFNAESMWGPSSDP--AWKRNDPMVNINQLVA
MSMEG_3580|M.smegmatis_MC2_155 PSEGWWPMLIGLAMNDAGGYNAESMWGPSTDP--AWKRNDPMVNINQLVA
Mb0134c|M.bovis_AF2122/97 PSEGWWPTLIGLAMNDSGGYNANSMWGPSSDP--AWKRNDPMVQIPRLVA
Rv0129c|M.tuberculosis_H37Rv PSEGWWPTLIGLAMNDSGGYNANSMWGPSSDP--AWKRNDPMVQIPRLVA
MMAR_0328|M.marinum_M PSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPRLVA
MUL_4793|M.ulcerans_Agy99 PSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPRLVA
MAV_5183|M.avium_104 PSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPRLVA
MLBr_02655|M.leprae_Br4923 PSEGWWPTMIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPRLVA
TH_2078|M.thermoresistible__bu LSEGWWPMLVGLAMGDAGGYDPNDMWGRTEDPNSAWKRNDPMVNIDKLVA
MAB_1579|M.abscessus_ATCC_1997 PSDQKW--QIRVAMSDAGGFNADDMWGPDSDP--AWARNDPFLHIDQLIA
*: * : :**.*:**::.:.*** ** ** ****:::* :*:*
Mflv_3335|M.gilvum_PYR-GCK NNTRIWIYCGTGTPSDLDSGTPGQNLMAAQFLEGFTLRTNVAFRDNYIAA
Mvan_3061|M.vanbaalenii_PYR-1 NNTRIWIYCGTGTPSDLDNGTPGNNLMAAQFLEGFTLRTNIAFRDNYIAA
MSMEG_3580|M.smegmatis_MC2_155 NNTRLWVYCGTGTPSELDAGVSGGNLLAAQFLEGLTLRTNLTFRDQYIAA
Mb0134c|M.bovis_AF2122/97 NNTRIWVYCGNGTPSDLG-----GDNIPAKFLEGLTLRTNQTFRDTYAAD
Rv0129c|M.tuberculosis_H37Rv NNTRIWVYCGNGTPSDLG-----GDNIPAKFLEGLTLRTNQTFRDTYAAD
MMAR_0328|M.marinum_M NNTRIWVYCGNGTPSDLG-----GDNMPAKFLEGLTLRTNQTFRDTYLAS
MUL_4793|M.ulcerans_Agy99 NNTRIWVYCGNGTPSDLG-----GDNMPAKFLEGLTLRTNQTFRDTYLAS
MAV_5183|M.avium_104 NNTRIWVYCGNGTPSDLG-----GDNVPAKFLEGLTLRTNEQFQNNYAAA
MLBr_02655|M.leprae_Br4923 NNTRIWVYCGNGAPNELG-----GDNIPAKFLESLTLSTNEIFQNTYAAS
TH_2078|M.thermoresistible__bu NNTRIWVFCGDGTPADIGAGVPEGDNFNAKFLESFTLRTNKTFQQEYIAA
MAB_1579|M.abscessus_ATCC_1997 NNTRLWIYCGSGDATDLDKDRNGLEVISGGVIEGQVIDSDKKFAEAYGSA
****:*::** * . ::. : . . .:*. .: :: * : * :
Mflv_3335|M.gilvum_PYR-GCK GGNNGVFNFPTSGTHSWGYWGQQLQQMKPDIQRVLGAQATA---------
Mvan_3061|M.vanbaalenii_PYR-1 GGTNGVFNFPTSGTHSWGYWGQQLQQMKPDIQRVLGAQATV---------
MSMEG_3580|M.smegmatis_MC2_155 GGTNAVFNFPPNGTHTWNYWGQQLLEMKPDIQRVLGAQSAT---------
Mb0134c|M.bovis_AF2122/97 GGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAPAA-
Rv0129c|M.tuberculosis_H37Rv GGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAPAA-
MMAR_0328|M.marinum_M GGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEAP
MUL_4793|M.ulcerans_Agy99 GGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEAP
MAV_5183|M.avium_104 GGRNGVFNFPANGTHSWPYWNQQLMAMKPDMQQVLLSGNTTAAPAQPAQP
MLBr_02655|M.leprae_Br4923 GGRNGVFNFPPNGTHSWPYWNQQLVAMKPDIQQILNGSNNNA--------
TH_2078|M.thermoresistible__bu GGKNGVFNFPDAGTHSWGYWGQQLQQMKPDIQRVLGVSAA----------
MAB_1579|M.abscessus_ATCC_1997 GGANAHFEFPKGGIHNWTYWGNQLRAMKADLVGYLTKPGTAAV-------
** *. *:** * *.* **.:** ** *: *
Mflv_3335|M.gilvum_PYR-GCK --------------
Mvan_3061|M.vanbaalenii_PYR-1 --------------
MSMEG_3580|M.smegmatis_MC2_155 --------------
Mb0134c|M.bovis_AF2122/97 --------------
Rv0129c|M.tuberculosis_H37Rv --------------
MMAR_0328|M.marinum_M AAPVAPAA------
MUL_4793|M.ulcerans_Agy99 AAPVAPAA------
MAV_5183|M.avium_104 AQPAQPAQPAQPAT
MLBr_02655|M.leprae_Br4923 --------------
TH_2078|M.thermoresistible__bu --------------
MAB_1579|M.abscessus_ATCC_1997 --------------