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VESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMDLKA ATQKPPGDSFKDGSYDPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKW SLYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEAKEMGLIGHVVPDGQALTKALELADAISANGPLAV QAILRSIRETECMPENEAFKIDTQIGIKVFLSDDAKEGPRAFAEKRAPNFQNR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3545 | echA19 | - | 100% (263) | enoyl-CoA hydratase |
M. bovis AF2122 / 97 | Mb1099c | echA8 | 1e-35 | 35.94% (256) | enoyl-CoA hydratase |
M. bovis AF2122 / 97 | Mb0694 | echA5 | 3e-35 | 38.06% (247) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_1542 | - | 1e-120 | 82.49% (257) | enoyl-CoA hydratase |
M. tuberculosis H37Rv | Rv3516 | echA19 | 1e-149 | 99.62% (263) | enoyl-CoA hydratase |
M. leprae Br4923 | MLBr_02402 | - | 1e-34 | 37.05% (251) | enoyl-CoA hydratase |
M. abscessus ATCC 19977 | MAB_4164 | - | 1e-117 | 79.15% (259) | enoyl-CoA hydratase |
M. marinum M | MMAR_5002 | echA19 | 1e-137 | 91.22% (262) | enoyl-CoA hydratase EchA19 |
M. avium 104 | MAV_0643 | - | 1e-138 | 91.98% (262) | enoyl-CoA hydratase |
M. smegmatis MC2 155 | MSMEG_5915 | - | 1e-124 | 84.88% (258) | enoyl-CoA hydratase |
M. thermoresistible (build 8) | TH_1820 | echA19 | 1e-126 | 84.94% (259) | POSSIBLE ENOYL-CoA HYDRATASE ECHA19 (ENOYL HYDRASE) |
M. ulcerans Agy99 | MUL_4076 | echA19 | 1e-136 | 90.46% (262) | enoyl-CoA hydratase |
M. vanbaalenii PYR-1 | Mvan_5216 | - | 1e-123 | 83.85% (260) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment Mb3545|M.bovis_AF2122/97 ------------------------MESGPDALVERRGHTLIVTMNRPAAR Rv3516|M.tuberculosis_H37Rv ------------------------MESGPDALVERRGHTLIVTMNRPAAR MMAR_5002|M.marinum_M -------------MAPNTSETPANGESGPDALVEQRGHTLIVTMNRPSRR MUL_4076|M.ulcerans_Agy99 ---MPDVMRKAVLVAPNTSETPANGESGPDALVEQRGHTLIVTMNRPSRR MAV_0643|M.avium_104 -----------------MAEASANEKTGPDALVEQRGHTLIVTLNRPHAR MSMEG_5915|M.smegmatis_MC2_155 ------------------MSE---TGKGPDALVEQRGHTLIVTLNRPEAR Mvan_5216|M.vanbaalenii_PYR-1 ------------------MSD---PQKGPDALVEQRGHTLIVTLNRPEAR Mflv_1542|M.gilvum_PYR-GCK MLHFQTSLWHRRWKADQFVSDEQNPEKAPDALVEQRGHTLIVTMNRPEKR TH_1820|M.thermoresistible__bu --------------VDQPVSA---LGSQPHALIEQRGHTLILTLNRPEAR MAB_4164|M.abscessus_ATCC_1997 -------MTEADALRASGSSHTVTEQDAPHALVELRDHVLIVTMNRPHAR MLBr_02402|M.leprae_Br4923 -------------------------MKYDTILVDGYQRVGIITLNRPQAL *:: :. *:*:*** Mb3545|M.bovis_AF2122/97 NALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAATQKPP Rv3516|M.tuberculosis_H37Rv NALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAATQKPP MMAR_5002|M.marinum_M NALSGEMMQIMVEAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAATKKPP MUL_4076|M.ulcerans_Agy99 NALSGEMMQIMVEAWDRVDNDPDIRCCILTGAGDYFCAGMDLKAATKKPP MAV_0643|M.avium_104 NALSTEMMEIMVQAWDRVDNDDDIRCCILTGAGGYFCAGMDLKAATKKPP MSMEG_5915|M.smegmatis_MC2_155 NALSGEMLSIMVEAWDRVDNDPEIRTCILTGAGGYFCSGMDLKGADKKPP Mvan_5216|M.vanbaalenii_PYR-1 NALSTEMLSIMVDAWNRVDEDPEIRTCILTGAGGYFCAGMDLKAASKKPP Mflv_1542|M.gilvum_PYR-GCK NALSAEMMQIMVEAWDRVDSDPEIRSCILTGAGGAFCAGMDLKKADSQAP TH_1820|M.thermoresistible__bu NALSTEMLATMVEAWDRVDNDPEIRTCILTGAGGYFCSGMDLKAATARPP MAB_4164|M.abscessus_ATCC_1997 NALSGEMLEIMTQAWDRVDNDPEVRVCILTGAGGYFCAGADLKAMNKRAP MLBr_02402|M.leprae_Br4923 NALNSQMMNEITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMASLTF ***. :*: :.:* ..:* * :: ::**: *.:* *:* . Mb3545|M.bovis_AF2122/97 GDSFKDGSYDPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRV Rv3516|M.tuberculosis_H37Rv GDSFKDGSYGPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRV MMAR_5002|M.marinum_M GDSFKDGSYDPSRIDALLKGRRLKKPLIAAVEGPAIAGGTEILQGTDIRV MUL_4076|M.ulcerans_Agy99 GDSFKDGSYDPSRIDALLKGRRLKKPLIAAVEGPAIAGGTEILQGTDIRV MAV_0643|M.avium_104 GESFKDGSYDPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRV MSMEG_5915|M.smegmatis_MC2_155 GDSFKDGSYDPSKIPGLLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRV Mvan_5216|M.vanbaalenii_PYR-1 GDSFADGSYDPSKIEGLLKGRRLKKPLIAAVEGPAIAGGTEILQGTDIRV Mflv_1542|M.gilvum_PYR-GCK GDSFKDGSYDPSKIPALLKGRRLKKPLIAAVEGAAIAGGTEILQGTDIRV TH_1820|M.thermoresistible__bu GDSFKDGSYDPSTIPALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRI MAB_4164|M.abscessus_ATCC_1997 GDQFSDGSYDPSVIPGLLKGRRLTKPLIAAVEGPAIAGGTEILQATDIRV MLBr_02402|M.leprae_Br4923 TDAFDADFFS-----AWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLI : * . :. . * : .*:**** * *:.** *: *: : Mb3545|M.bovis_AF2122/97 AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEA Rv3516|M.tuberculosis_H37Rv AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEA MMAR_5002|M.marinum_M AAESAKFGISEAKWSLYPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEA MUL_4076|M.ulcerans_Agy99 AAESAKFGISEAEWSLYPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEA MAV_0643|M.avium_104 AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEA MSMEG_5915|M.smegmatis_MC2_155 AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTIACDMLLTGRHITAAEA Mvan_5216|M.vanbaalenii_PYR-1 AGESAKFGISEAKWSLYPMGGSAVRLPRQIPYTIACDLLLTGRHITAAEA Mflv_1542|M.gilvum_PYR-GCK AGESAKFGVSEAKWSLYPMGGSAVRLVRQIPYTVACDILLTGRHISAAEA TH_1820|M.thermoresistible__bu AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTIAADLLLTGRHITAAEA MAB_4164|M.abscessus_ATCC_1997 AGESAKFGVSEVKWSLYPMGGSAVRLPRQIPYTVACDILLTGRHIKAPEA MLBr_02402|M.leprae_Br4923 AADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEA *.::**** .* : .: * *.: ** * * : * *::**** * *.** Mb3545|M.bovis_AF2122/97 KEMGLIGHVVPDGQALTKALELADAISANGPLAVQAILRSIRETECMPEN Rv3516|M.tuberculosis_H37Rv KEMGLIGHVVPDGQALTKALELADAISANGPLAVQAILRSIRETECMPEN MMAR_5002|M.marinum_M KEMGLVGHVVPDGQALTKALEIAEIIAANGPLAVQAILRTIRETEGMHEN MUL_4076|M.ulcerans_Agy99 KEMGLVGHVVPDGQALTKALEIAEIIAANGPLAVQAILRTIRETEGMHEN MAV_0643|M.avium_104 KEMGLIGHVVPDGQALAKALEIAEVIENNGPLAVQAILRAIRETEGMHEN MSMEG_5915|M.smegmatis_MC2_155 KEYGLIGYVVPDGTALDKALEIAETINNNGPLAVQAILKTIRETEGMHED Mvan_5216|M.vanbaalenii_PYR-1 LQYGLIGHVVPDGTALDKALEIAEVINNNGPLAVQAILKTIRETEGMHEE Mflv_1542|M.gilvum_PYR-GCK KEFGLIGHVVPDGQALTKALEIAEVINGNGPLAVQAILKTIRETEGMHEE TH_1820|M.thermoresistible__bu KEIGLIGYVVPDGTALDKALEIAEVINNNGPLAVQAILRSIRETEGLPEN MAB_4164|M.abscessus_ATCC_1997 KDIGLIGHVVPDGQALEKALELANMIAGNGPLAVQAVLKTIRDSEGMHEN MLBr_02402|M.leprae_Br4923 ERSGLVSRVVLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLA **:. ** . * :* :* * . *.: .::. : Mb3545|M.bovis_AF2122/97 EAFKIDTQIGIKVFLSDDAKEGPRAFAEKRAPNFQNR Rv3516|M.tuberculosis_H37Rv EAFKIDTQIGIKVFLSDDAKEGPRAFAEKRAPNFQNR MMAR_5002|M.marinum_M EAFKIDTRIGIEVFLSDDAKEGPQAFAQKRKPNFQNR MUL_4076|M.ulcerans_Agy99 EAFKIDTRIGIEVFLSDDAKEGPQAFAQKRKPNFQNR MAV_0643|M.avium_104 EAFKIDTQIGIKVFLSEDAKEGPRAFAEKRKPNFQNR MSMEG_5915|M.smegmatis_MC2_155 EAFGPDTRNGIPVFLSEDAKEGPRAFKEKRAPNFQMK Mvan_5216|M.vanbaalenii_PYR-1 EAFKPDTANGIPVFLSEDAKEGPRAFKEKRAPNFQMK Mflv_1542|M.gilvum_PYR-GCK EAFKPDTANGIPVFLSEDSKEGPKAFLEKRKPVWKLK TH_1820|M.thermoresistible__bu EAFKIDTKIGIEVFLSEDAKEGPRAFKEKRKPVFKMK MAB_4164|M.abscessus_ATCC_1997 EAFKADTKVGIGVFTSNDAKEGPRAFAEKRAPNFTGS MLBr_02402|M.leprae_Br4923 EGLLHERRLFHSTFVTDDQSEGMAAFIEKRAPQFTHR *.: : .* ::* .** ** :** * :