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TVPGSVDALTACWLTEALRSDPTLSDTLTVDGVRAERIAMDSGFSSLLYRLHLTGTGVPATVIAKLPAES EARGAMELLGGYRRELAFYRNVAGRAPLDTPHVYTAQIAEDSVDFVLLLEDLRDWDNADHLVGLTVEQTR LAVTNLAGLHAWSVDPSNSAALQHFPSLSTPIVRDLLVPAFAPGWQVYRDRSGAAVPRRIARFADRFAEL APQALAALVEHSMLLHGDIRADNMFFDGGRLKIVDFQFASVGSGAADIAYLVSQGLPTDARRGHDETLMR EYLGMLGVPYRFDDAWRHYRFAVAYLMVLPVIILVGWDSLPERSRALCLELTSRAIAAIDDVDATEVFA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4330 | - | - | 100% (350) | hypothetical protein Mflv_4330 |
| M. gilvum PYR-GCK | Mflv_3102 | - | 2e-24 | 27.91% (369) | aminoglycoside phosphotransferase |
| M. gilvum PYR-GCK | Mflv_4117 | - | 3e-21 | 29.47% (319) | hypothetical protein Mflv_4117 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4035 | - | 7e-29 | 28.61% (367) | hypothetical protein MMAR_4035 |
| M. avium 104 | MAV_1568 | - | 1e-28 | 30.26% (380) | phosphotransferase enzyme family protein, putative |
| M. smegmatis MC2 155 | MSMEG_3876 | - | 5e-25 | 27.08% (373) | phosphotransferase enzyme family protein, putative |
| M. thermoresistible (build 8) | TH_3623 | - | 5e-30 | 30.17% (348) | PUTATIVE putative aminoglycoside phosphotransferase |
| M. ulcerans Agy99 | MUL_1045 | - | 2e-14 | 27.79% (349) | hypothetical protein MUL_1045 |
| M. vanbaalenii PYR-1 | Mvan_2016 | - | 1e-161 | 79.04% (353) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4330|M.gilvum_PYR-GCK ---------------MTVPGSVDALTACWLTEALRSDPTLSDTLTVDGVR
Mvan_2016|M.vanbaalenii_PYR-1 ---MTSGDVTDAGSATAVPGGVAGLTPQWLTAVLRTDAGLPDTATVSEVR
MMAR_4035|M.marinum_M --------------MVSIPRHPTDVTPQWLAAVLGERG--TPVGVSGVDV
MAV_1568|M.avium_104 --------------MLSIPRYPGDVTPQWLSAALSGRG--APVEVAEVDV
MSMEG_3876|M.smegmatis_MC2_155 -----------MTAAVSIPGRPVDVTPSWLSGVLG-------TEVATAAT
TH_3623|M.thermoresistible__bu --------------MAFTDYTIAELTPEALAAVLRRRPGWEALTVTTVES
MUL_1045|M.ulcerans_Agy99 MIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDPPALSEIMGRRV
.. :. :
Mflv_4330|M.gilvum_PYR-GCK AERIAMDSGFSSLLYRLHLTG-TGVPATVIAKLPAESEARGAMELLGG-Y
Mvan_2016|M.vanbaalenii_PYR-1 AERIAADSGFSSLLYRLHLTGGDGLPATLIAKLPAESQARGAMELLGG-Y
MMAR_4035|M.marinum_M VPIGTGQTGATYRLTVIYDPDPAGLPDTFVIKLPAQDDTVRDRVVVG--Y
MAV_1568|M.avium_104 AAIGTGQTGATYRVTARYATDPGDLPQTFVIKLPAQDDTVRDRVVIG--Y
MSMEG_3876|M.smegmatis_MC2_155 EPIGTGQTGATYRVTVTYAGDS-ALPTTFAIKLPSQDDTVRDRVAIG--Y
TH_3623|M.thermoresistible__bu QPVGTGQMASSYRLTLGYAGDSGSAPDTLIAKISSTDETSWQMAVATGAY
MUL_1045|M.ulcerans_Agy99 SSVSVLDDSSGTTSRARLALSGNDVPESVFVKMAAATAATRFIGELGRLA
. : . . * :. *:.: :
Mflv_4330|M.gilvum_PYR-GCK RRELAFYRNVAGRAPLDTPHVYTAQIAEDSVDFVLLLEDLRDWDN-----
Mvan_2016|M.vanbaalenii_PYR-1 RREIAFYRDVAGRAPLDTPRVYAARMAEDSVDFVLLLEDLRDWDN-----
MMAR_4035|M.marinum_M RSECAFYSSVADRVRVPTPRCFYCEITEDAMDFALLLEDQAPAVQ-----
MAV_1568|M.avium_104 RSECAFYSSVADRVQVPTPRCFYSEITEDAMDFALLLADQAPAVQ-----
MSMEG_3876|M.smegmatis_MC2_155 RSEHAFYTSLAGQVRIPVPHCYHCEIAGEGADFVLVLADMAPAEQ-----
TH_3623|M.thermoresistible__bu EREVRYYQHLSGLAATRTPECYFAEIADDRCGFALLLEDMGPADT-----
MUL_1045|M.ulcerans_Agy99 ETEVSFYRDLSPELAPDAPTAYGCAFDPLTGRFVLVLEDLAAPAEGTCDF
. * :* :: .* : . : *.*:* *
Mflv_4330|M.gilvum_PYR-GCK ADHLVGLTVEQTRLAVTNLAGLHAWSVDPSNSAALQHFP-SLSTPIVRDL
Mvan_2016|M.vanbaalenii_PYR-1 ADHLAGLSMDRARLAVANLAALHAWSVEPANAVALQSFP-SLATSVVRDL
MMAR_4035|M.marinum_M GDQLTGCGEREARLAVVALAGLHGPSWCDPVWLDQPGIAFPFPDEPFANG
MAV_1568|M.avium_104 GDQLLGCGETEARLAVTALAGLHAPSWCDPVWLDFPGIAFGRPDEAGAGG
MSMEG_3876|M.smegmatis_MC2_155 GDQIAGCSPAEAALAVRALADLHGPTWCDPQWANFPGIAMPKPEPDSAKG
TH_3623|M.thermoresistible__bu IDQISGCTADQADLALGQAAALHGSSWAHAALRDND----WLPAQGAWAK
MUL_1045|M.ulcerans_Agy99 SDTLHPFDNDQAALVVELLARLHATYWVRLNHGGVRPFG--WRYAASRDP
* : .: *.: * **.
Mflv_4330|M.gilvum_PYR-GCK LVPAFAPGWQVYRDRSGAAVPRRIARFADRFAELAPQALAALVEHSMLLH
Mvan_2016|M.vanbaalenii_PYR-1 LVPAFAPGWQIYRDKSGAAVPRRVARFAERFAEMAPQALSALTEHSMLLH
MMAR_4035|M.marinum_M LGEVARMSAEITLDKLGDRLSAADRETFTETMNLVTPWLLAERDRFALLH
MAV_1568|M.avium_104 MGEVAKMSADITLERLGDRMSAEDRETFAAAMGVIAPWLLSEYDRFALLH
MSMEG_3876|M.smegmatis_MC2_155 FGDIAKMAADITLDKLGDRLSIGDRETLSASMSVVTPWLLAEPDRFAVLH
TH_3623|M.thermoresistible__bu LADAIPHITPMWLDRFGAHLRPEHIPVVEQLGDHVSAWLETLTEHRSLWH
MUL_1045|M.ulcerans_Agy99 SVPLVPTMLRASWRRLGGHAAALLPGRDFVFEHYRAITGLIDAPPHTVLH
: * . : *
Mflv_4330|M.gilvum_PYR-GCK GDIRADNMFFDGGR----LKIVDFQFASVGSGAADIAYLVSQGLPTDARR
Mvan_2016|M.vanbaalenii_PYR-1 GDIRADNMFFDGDR----LKIVDFQFASVGCGAADIGYLVSQGLPSEVRR
MMAR_4035|M.marinum_M GDYRLDNLLFDPDL--RRVAVVDWQTLGIGLPARDLGYFTATSLNSQLRS
MAV_1568|M.avium_104 GDYRLDNLLFDPDR--TRVSVVDWQTLGVGLPARDLAYFTATSLDSPLRA
MSMEG_3876|M.smegmatis_MC2_155 GDYRLDNMLFDPDR--TRVTVVDWQTLGSGLPARDLSYFTATSLDPADRA
TH_3623|M.thermoresistible__bu GDFRLDNLLFGAQAGATPIAVVDWQSVASGPGVIDVSYFLGNSMTEDHRA
MUL_1045|M.ulcerans_Agy99 GDAHPGNWYFRSSGGPLAAGLLDWQAIRLGHPARDLAYTLITGMTTTDRR
** : .* * ::*:* * . *:.* .: *
Mflv_4330|M.gilvum_PYR-GCK GHDETLMREYLGMLG----VPYRFDDAWRHYRFAVAYLMVLPVIILVGWD
Mvan_2016|M.vanbaalenii_PYR-1 GHDESLVREYLGALQDRGLVSYQFDDAWRHYRFAVAYLMVLPVITLIGWD
MMAR_4035|M.marinum_M DIEESLVDDYHRKLLSYGVTGYDWETCWRDYRLGMPHTVLISALGFA-FA
MAV_1568|M.avium_104 AIEEELVADYHRALVAGGVNGYDRETCWRDYRLGVLQAPLISALGFA-FA
MSMEG_3876|M.smegmatis_MC2_155 AAERDLVGEYHRTLLAHGVTGYDRETCWRDYRLGMLQAPLITVLGCA-FA
TH_3623|M.thermoresistible__bu EHERELVGEYHRRLLSHGVQGYSADRCWLEYRAHAVFGLMLTVPVSL-GV
MUL_1045|M.ulcerans_Agy99 VTERELLDVYRRALAAAGGPELDREEPWLRYRQAAACAYVATTIAAG---
:. *: * * : * ** : ..
Mflv_4330|M.gilvum_PYR-GCK SLPERSRALCLELTSRAIAAIDDVDATEVFA-------------------
Mvan_2016|M.vanbaalenii_PYR-1 TLPERSRALCLELTARAVATADDIDAMEVFA-------------------
MMAR_4035|M.marinum_M TATERGDEMVLTMLGRGCQAIRDLETLELIG-------------------
MAV_1568|M.avium_104 AATERGDDMVLTMLGRGCRAIRELGTLELIG-------------------
MSMEG_3876|M.smegmatis_MC2_155 SSTDRGDDMMVVMAQRGCQAIRELGTLDLIDAAS----------------
TH_3623|M.thermoresistible__bu QATERGDKMFAAMATRAAAQILENESYTALKCL-----------------
MUL_1045|M.ulcerans_Agy99 LGGMQAADIALTGLDLTVAALHDLQTVAALRAADLGGTSWAWRPGMARSA
:. : : : :
Mflv_4330|M.gilvum_PYR-GCK ---------------------------------
Mvan_2016|M.vanbaalenii_PYR-1 ---------------------------------
MMAR_4035|M.marinum_M ---------------------------------
MAV_1568|M.avium_104 ---------------------------------
MSMEG_3876|M.smegmatis_MC2_155 ---------------------------------
TH_3623|M.thermoresistible__bu ---------------------------------
MUL_1045|M.ulcerans_Agy99 RIRPGASARRCPMVWSTSSHILGVSRHFAMGAW