For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TLGYVPGATPAKWARHWADRHPEAPLRLHGVTAADAAAAVRDGSVDVALLRLPTETSGLAVIPLYEEMTV AVVTAEHVLTAADNVDATELHDEAILIPADTVVDWPDAPGTPVEHRPETTEAAVELVAAGVGVLLVPQSL ARLHHRKDLTYRPIVDAPTCPVALAFPEGPQSELLEEFIGIVRGRRPGSSRGQTQPERKRTAREKTLAKQ AARAAAGKVARKPGRSRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4302 | - | - | 100% (229) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1356 | - | 2e-09 | 27.87% (183) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1346 | - | 3e-08 | 26.29% (175) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_02041 | oxyR | 9e-11 | 29.87% (154) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3409c | - | 2e-91 | 71.18% (229) | LysR family transcriptional regulator |
| M. marinum M | MMAR_2756 | oxyR | 4e-08 | 32.73% (110) | hydrogen peroxide-inducible genes activator, OxyR |
| M. avium 104 | MAV_2838 | - | 6e-12 | 33.59% (131) | hydrogen peroxide-inducible genes activator |
| M. smegmatis MC2 155 | MSMEG_0471 | - | 2e-10 | 27.75% (191) | transcriptional regulator LysR family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 8e-10 | 33.64% (110) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_2045 | - | 5e-98 | 76.42% (229) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02041|M.leprae_Br4923 --------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQA
MAV_2838|M.avium_104 --------MPDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQA
MMAR_2756|M.marinum_M MLATILIGMTDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MUL_2998|M.ulcerans_Agy99 -----MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MAB_3409c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2045|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4302|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0471|M.smegmatis_MC2_155 -------------MEWTLRELRVFVTAADTGSFTDAAAQLHVSQAAVSRT
MLBr_02041|M.leprae_Br4923 LAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGE
MAV_2838|M.avium_104 LAALEAGLGTQLVERSTRRVFLTPQGAELLPHAQAVVEAADAFTAAAAGS
MMAR_2756|M.marinum_M LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MUL_2998|M.ulcerans_Agy99 LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MAB_3409c|M.abscessus_ATCC_199 MTSPSLTLGYVPGGTPAKWARIWTQRHPDVSLQLRAVTAAEAADVVRDGA
Mvan_2045|M.vanbaalenii_PYR-1 MTRCSLTLGYVPGGTPAKWARIWAERHPEAPLQLRTLAAADAAAEVRAGI
Mflv_4302|M.gilvum_PYR-GCK -----MTLGYVPGATPAKWARHWADRHPEAPLRLHGVTAADAAAAVRDGS
MSMEG_0471|M.smegmatis_MC2_155 IAGLEKIVGDRLLRRVPRGCELTAAGQQILPLARRVLAEAESFTEFLHSR
:. .: . . : :: .
MLBr_02041|M.leprae_Br4923 SDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLLTA
MAV_2838|M.avium_104 ADPLRAGMRLGLIPTVAPYVLPTVLAGIAERRPGLTLRVTEDQTERLLAV
MMAR_2756|M.marinum_M ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVIEDQTERLLTA
MUL_2998|M.ulcerans_Agy99 ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVIEDQTERLLTA
MAB_3409c|M.abscessus_ATCC_199 VD-------------IALLRPPAETSGLALIPLYEETTVAVIPTDHLLSA
Mvan_2045|M.vanbaalenii_PYR-1 VD-------------VAVLRLPADTSGLSVIPLYEETTVAVVPTDHILTA
Mflv_4302|M.gilvum_PYR-GCK VD-------------VALLRLPTETSGLAVIPLYEEMTVAVVTAEHVLTA
MSMEG_0471|M.smegmatis_MC2_155 HG-------------VLRLGYAWAAVGRHTARLQRDWAQRQADIELELVR
. : . * : *
MLBr_02041|M.leprae_Br4923 LREGALDAAMIALPVETAGIAEIPIYDEDFVLALPPGHPLSGKRRVPTTA
MAV_2838|M.avium_104 LREGALDAALIALPAETAGVTAIPIYDEDFVLALPPGHPLAGKRRVPATA
MMAR_2756|M.marinum_M LREGSLDTALIALPADYGGLTEIPIYEEDFVLALPPGHPMADRHGVPVAA
MUL_2998|M.ulcerans_Agy99 LREGSLDTALIALPADYGGLTEIPIYEEDFVLALPPGHPMADRHGVPVAA
MAB_3409c|M.abscessus_ATCC_199 VDV--------ITAADLDGEPTLLPLDDVLAWADAPGIPVGHR---PETT
Mvan_2045|M.vanbaalenii_PYR-1 ADE--------ITAADLDGEPVLLPLDNVVAWADAPGDPVHHR---PETT
Mflv_4302|M.gilvum_PYR-GCK ADN--------VDATELHDEAILIPADTVVDWPDAPGTPVEHR---PETT
MSMEG_0471|M.smegmatis_MC2_155 HNSPTAGLAEGLCDVAVIRRPTDEKRFASVIVGLERRLVAFASDDEQWSG
. . . :
MLBr_02041|M.leprae_Br4923 LAQLPLLLLDEGHCLRDQTLDICRKSGVQAELANTRAASLATAVQCVTGG
MAV_2838|M.avium_104 LADLPLLLLDEGHCLRDQALDVCHKAGVRAELANTRAASLATAVQCVTGG
MMAR_2756|M.marinum_M LSELPLLLLDEGHCLRDQALDVCQNAGVRAELADTRAASLATAVQCVNGG
MUL_2998|M.ulcerans_Agy99 LSELPLLLLDEGHCLRDQALDVCQNAGVRAEHADTRADSLATAVQCVNGG
MAB_3409c|M.abscessus_ATCC_199 ADAIELVAAGLGALIVPQSLARLHHR------KDLTYRPIADAPTCP---
Mvan_2045|M.vanbaalenii_PYR-1 SDAIELVAAGVGALIVPQSLARLYHR------KDLTYRAIADAPTCP---
Mflv_4302|M.gilvum_PYR-GCK EAAVELVAAGVGVLLVPQSLARLHHR------KDLTYRPIVDAPTCP---
MSMEG_0471|M.smegmatis_MC2_155 RRQLSMAEIADRTVIIDPRIGTTSSELWEGSGHVPQFIVSTDVDTWLDAI
: : : : . .
MLBr_02041|M.leprae_Br4923 LGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASYRQ
MAV_2838|M.avium_104 LGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLVFRSSSGRDDSYRE
MMAR_2756|M.marinum_M LGVTLIPQSAVSVEAARSRVGLAHFAAPTPGRRIGLVYRASSGRDEAYRQ
MUL_2998|M.ulcerans_Agy99 LGVTLIPQSAVSVEAARSRVGLTHFAAPTPGRRIGLVYRASSGRDEAYRQ
MAB_3409c|M.abscessus_ATCC_199 --VALAFPDGQQPPLVEEFIGIVRGRKPDSSRGKAGSAPKRTAREKTLAK
Mvan_2045|M.vanbaalenii_PYR-1 --VALAFPEGAQSPLVEEFIGIVRGRKPGSSRGQAQSAPKRTAREKTLAK
Mflv_4302|M.gilvum_PYR-GCK --VALAFPEGPQSELLEEFIGIVRGRRPGSSRGQTQPERKRTAREKTLAK
MSMEG_0471|M.smegmatis_MC2_155 AAGRGVGTTAEATAHHHPRHGVTYRPIKDGPRIAVRLAWWRDHRPRGLDE
. . *:. * * :
MLBr_02041|M.leprae_Br4923 IAKIIGELISTEHHVRLVA---
MAV_2838|M.avium_104 LAGLIGELISSQHQVRLVK---
MMAR_2756|M.marinum_M LAAIMGESISNEQQVRLVN---
MUL_2998|M.ulcerans_Agy99 LAAIMGESISNEQQVRLVN---
MAB_3409c|M.abscessus_ATCC_199 QAARAAAGKVARDPGRPKRGRR
Mvan_2045|M.vanbaalenii_PYR-1 QAARAAAGKVARKPGRAERGRR
Mflv_4302|M.gilvum_PYR-GCK QAARAAAGKVARKPGRSRR---
MSMEG_0471|M.smegmatis_MC2_155 LVDAVTRLYST-----------
.