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MGLRGLTGKVAVVAGGATGLGAAAATRLAEEGCRVVVGDVSEDAATHTVRRITEAGGTAVAIAFDLADPS SVAGLFASAVDAFSDVDLLFNVGADMSTIRFDTDVVDIDLDVWDRVMTVNLRGYAAALKYAIPVMLEGGG GAIVNMSSAAAFQGEPARPAYATAKAGIGALTRHVASRWGKDGIRCNAVAPGFTATDTIRAAPQWPELEA GALRRIRGPRVGAPSDVAGLVAFLLSEEGEWINGQVVNIDGGTVLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3483 | - | - | 100% (256) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_1829 | - | 2e-57 | 46.09% (256) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_1601 | - | 6e-41 | 37.84% (259) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0792 | - | 3e-39 | 37.10% (248) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0769 | - | 1e-39 | 37.50% (248) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-23 | 29.76% (252) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_1219 | - | 2e-36 | 35.08% (248) | short chain dehydrogenase |
| M. marinum M | MMAR_0271 | - | 3e-40 | 38.46% (247) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_4177 | - | 1e-115 | 80.47% (256) | putative short-chain type dehydrogenase/reductase y4lA |
| M. smegmatis MC2 155 | MSMEG_2536 | - | 1e-37 | 37.05% (251) | 3-oxoacyl- |
| M. thermoresistible (build 8) | TH_3037 | - | 3e-41 | 37.90% (248) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_4844 | - | 8e-38 | 37.25% (247) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_5156 | - | 7e-41 | 37.75% (249) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3483|M.gilvum_PYR-GCK -------------MGLRGLTGKVAVVAGGATGLGAAAATRLAEEGCRVVV
MAV_4177|M.avium_104 -------------MGLRGLADKVAVVVGGATGIGAATAARLAGEGCRVVI
MMAR_0271|M.marinum_M --------------MTAELENKVAIITGACGGIGLETSRVLARAGARVVL
MUL_4844|M.ulcerans_Agy99 --------------MTAELENKVAIITGACGGIGLETSRVPACAGARVVL
Mb0792|M.bovis_AF2122/97 -----------------MFDSKVAIVTGAAQGIGQAYAQALAREGASVVV
Rv0769|M.tuberculosis_H37Rv -----------------MFDSKVAIVTGAAQGIGQAYAQALAREGASVVV
MAB_1219|M.abscessus_ATCC_1997 -----------MG----EFDNKVAIVTGAAQGIGEAYAHALAREGAAVVV
TH_3037|M.thermoresistible__bu -----------MG----QFDDKVAIVTGAGGGIGQAYAEALAREGAAVVV
Mvan_5156|M.vanbaalenii_PYR-1 -----------MGLYGDQFKEKVAIVTGAGGGIGQAYAEALAREGAAVVV
MSMEG_2536|M.smegmatis_MC2_155 ----------------MRLANRVAIITGAAQGIGRIYAERFAEEGAAVVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: : ::.*. *:* : . * *.:
Mflv_3483|M.gilvum_PYR-GCK GDVSEDAATHTVRRITEAGGTAVAIAFDLADPSSVAGLFASAVDAFSDVD
MAV_4177|M.avium_104 GDVAVDAARQTADRIGAAGGTATQVAFDLADPASVATLIDCAATTYGGVD
MMAR_0271|M.marinum_M ADLPETDLAGAAASVGRG---AVHHVVDLTNEVSVRALIDFTIDTFGRLD
MUL_4844|M.ulcerans_Agy99 ADLPETDLAGAAASVGRG---AVHHVVDLTNEVSVRALIDFTIDTFGRLD
Mb0792|M.bovis_AF2122/97 ADINADGAAAVAKQIVADGGTVIHVPVDVSDEDSAKAMVDRAVGAFGGID
Rv0769|M.tuberculosis_H37Rv ADINADGAAAVAKQIVADGGTAIHVPVDVSDEDSAKAMVDRAVGAFGGID
MAB_1219|M.abscessus_ATCC_1997 ADINAEMGEGVAKQIVADGGRAIFAGVDVSDPDSAIAMADKAVSEFGGID
TH_3037|M.thermoresistible__bu ADINTEGAQKVADGIKGEGGDALAVPVDVSDPESAEEMAAQTVSEFGGID
Mvan_5156|M.vanbaalenii_PYR-1 ADINTEGAQKVADGIKGEGGNALAVRVDVSDPESAKGMAAQTLSEFGGID
MSMEG_2536|M.smegmatis_MC2_155 ADINEPKATEVASSITSLGGRAIAAAVDVSDVESVNRMVDSAVEAFGTVD
MLBr_01807|M.leprae_Br4923 THRASVVPDWFFG-----------VECDVTDNDAIGAAFKAVEEHQGPVE
. *::: : . . ::
Mflv_3483|M.gilvum_PYR-GCK LLFNVGADMSTIRFDTDVVDIDLDVWDRVMTVNLRGYAAALKYAIPVMLE
MAV_4177|M.avium_104 LLFNVGADMSTIRADTDVVDIDFDVWDRVMTVSLRGYVAAMKYAIPRMLD
MMAR_0271|M.marinum_M IVDNNAAHSD--PADMLVTQMTVDVWDDTFTVNARGTMLMCKYAIPRLIS
MUL_4844|M.ulcerans_Agy99 IVDNNAAHSD--PADMLVSQMTVDVWDDTFTVNARGTMLMCKYAIPRLIS
Mb0792|M.bovis_AF2122/97 YLVNNAAIYGGMKLDLLLT-VPLDYYKKFMSVNHDGVLVCTRAVYKHMAK
Rv0769|M.tuberculosis_H37Rv YLVNNAAIYGGMKLDLLLT-VPLDYYKKFMSVNHDGVLVCTRAVYKHMAK
MAB_1219|M.abscessus_ATCC_1997 YLVNNAAIYGGMKLDLLLS-VPWDYYKKFMSVNQDGALVCTRAVYKHIAQ
TH_3037|M.thermoresistible__bu YLVNNAAIFGGMKLDFLIT-VDWDYYKRFMSVNLDGALVCTRAVYKKMAK
Mvan_5156|M.vanbaalenii_PYR-1 YLVNNAAIFGGMKLDFLIT-VDWDYYKKFMSVNMDGALVCTRAVYRKMAK
MSMEG_2536|M.smegmatis_MC2_155 ILVNNAAIFSTLKMKPFEE-ISGDEWDKLFAVNAKGTFLCCQAVSPVMRK
MLBr_01807|M.leprae_Br4923 VLVANAGITS----DMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIK
: .. . . : : :. : *. * : . : .
Mflv_3483|M.gilvum_PYR-GCK GGGGAIVNMSSAAAFQGEPARPAYATAKAGIGALTRHVASRWGKDGIRCN
MAV_4177|M.avium_104 RGGGAIVNMSSAAAFQGEPARPAYATAKAGIGALTRHVASRWGKDNIRCN
MMAR_0271|M.marinum_M AGGGAIVNISSATAHAAYDMSTAYACTKAAIETLTRYVATQYGRHGVRCN
MUL_4844|M.ulcerans_Agy99 AGGGAIVNISSATAHAAYDMSTAYSCTKAAIETLTRYVATQYGRHGVRCN
Mb0792|M.bovis_AF2122/97 RGGGAIVNQSS---TAAWLYSNFYGLAKVGVNGLTQQLARELGGMKIRIN
Rv0769|M.tuberculosis_H37Rv RGGGAIVNQSS---TAAWLYSNFYGLAKVGVNGLTQQLARELGGMKIRIN
MAB_1219|M.abscessus_ATCC_1997 RGGGAIVNQSS---TAAWLYSGFYGLAKVGINGLTQQLSRELGGQKIRIN
TH_3037|M.thermoresistible__bu RGGGAIVNQSS---TAAWLYSNYYGLAKAGLNSLTQQLATELGGQNIRVN
Mvan_5156|M.vanbaalenii_PYR-1 RGGGAIVNQSS---TAAWLYSNFYGLAKVGINGLTQQLATELGGQNIRVN
MSMEG_2536|M.smegmatis_MC2_155 NQYGRIINISSSVVVTGRPNYAHYIASKGAVWALTHALATEMGTDGITVN
MLBr_01807|M.leprae_Br4923 QRFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITAN
* : .* . * :* .: ::: :: . * : *
Mflv_3483|M.gilvum_PYR-GCK AVAPGFTATDTIRAAPQWPELEAGALRRIRGPRVGAPSDVAGLVAFLLSE
MAV_4177|M.avium_104 AVAPGFTATETIRSVPQWPELEAAALKRIRGPRVGDPADVAALVAFLLSA
MMAR_0271|M.marinum_M AIAPGLVRTPRLEVGLPQPIVDIFATHHLAG-RIGEPHEIAELVCFLASD
MUL_4844|M.ulcerans_Agy99 AIAPGLVRTPRLEVGLPQPIVDIFATHHLAG-LIGEPHEIAELVCFLASD
Mb0792|M.bovis_AF2122/97 AIAPGPIDTEATRTVTPA-ELVKNMVQTIPLSRMGTPEDLVGMCLFLLSD
Rv0769|M.tuberculosis_H37Rv AIAPGPIDTEATRTVTPA-ELVKNMVQTIPLSRMGTPEDLVGMCLFLLSD
MAB_1219|M.abscessus_ATCC_1997 AIAPGPTDTEATRGTVPE-QFRSELVKNIPLSRMGTVDDMVGMCLFLLSD
TH_3037|M.thermoresistible__bu AIAPGPIDTEANRSTTPK-EMVDDIVKRIPLSRLGEPEDLVGMCLFLLSD
Mvan_5156|M.vanbaalenii_PYR-1 AIAPGPIDTEANRTTTPQ-EMVADIVKGIPLSRMGEPEDLVGMLLFLLSD
MSMEG_2536|M.smegmatis_MC2_155 TVSPHGIITEIPRETISE-EGWRRNLEEQALKRKGDASDLVGILLYLASD
MLBr_01807|M.leprae_Br4923 VVAPGFIDTEMTRAMDSK--YQEAALQAIPLGRIGAVEEIAGAVSFLASE
.::* * . . * ::. :* *
Mflv_3483|M.gilvum_PYR-GCK EGEWINGQVVNIDGGTVLR-------------------
MAV_4177|M.avium_104 EGDWINGQVINIDGGTVLR-------------------
MMAR_0271|M.marinum_M RAAFITGQVIAADSGLLAHLPGLPQIRASVAELQSQPS
MUL_4844|M.ulcerans_Agy99 RAAFITGQVIAADSGLLAHLPGLPQIRASVAELQSQPS
Mb0792|M.bovis_AF2122/97 SASWITGQIFNVDGGQIIRS------------------
Rv0769|M.tuberculosis_H37Rv SASWITGQIFNVDGGQIIRS------------------
MAB_1219|M.abscessus_ATCC_1997 KASWITGQVFNVDGGQIIRS------------------
TH_3037|M.thermoresistible__bu QAKWITGQIFNVDGGQIIR-------------------
Mvan_5156|M.vanbaalenii_PYR-1 QAKWITGQIFNVDGGQIIRS------------------
MSMEG_2536|M.smegmatis_MC2_155 ESKFMTGQTVALDAGLRFT-------------------
MLBr_01807|M.leprae_Br4923 DAGYISGAVIPVDGGLGMGH------------------
. ::.* . *.*