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M. abscessus ATCC 19977 MAB_1219 (-)

annotation: short chain dehydrogenase
coordinates: 1231688 - 1232440
length: 250

MGEFDNKVAIVTGAAQGIGEAYAHALAREGAAVVVADINAEMGEGVAKQIVADGGRAIFAGVDVSDPDSA
IAMADKAVSEFGGIDYLVNNAAIYGGMKLDLLLSVPWDYYKKFMSVNQDGALVCTRAVYKHIAQRGGGAI
VNQSSTAAWLYSGFYGLAKVGINGLTQQLSRELGGQKIRINAIAPGPTDTEATRGTVPEQFRSELVKNIP
LSRMGTVDDMVGMCLFLLSDKASWITGQVFNVDGGQIIRS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_1219--100% (250)short chain dehydrogenase
M. abscessus ATCC 19977MAB_4178c-3e-3135.16% (256) short chain dehydrogenase
M. abscessus ATCC 19977MAB_4680c-8e-3136.03% (247) putative short-chain dehydrogenase/reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0792-1e-11180.57% (247) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1601-1e-10474.90% (247) short chain dehydrogenase
M. tuberculosis H37RvRv0769-1e-11280.97% (247) short chain dehydrogenase
M. leprae Br4923MLBr_01807fabG14e-2434.66% (251) 3-oxoacyl-
M. marinum MMMAR_4927-1e-11582.00% (250) dehydrogenase/reductase
M. avium 104MAV_0714-1e-10878.14% (247) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_5858-1e-10476.11% (247) short chain dehydrogenase
M. thermoresistible (build 8)TH_3037-1e-10473.49% (249) PUTATIVE short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99MUL_0478-1e-11381.20% (250) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_5156-1e-10374.19% (248) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0792|M.bovis_AF2122/97            -----------------MFDSKVAIVTGAAQGIGQAYAQALAREGASVVV
Rv0769|M.tuberculosis_H37Rv         -----------------MFDSKVAIVTGAAQGIGQAYAQALAREGASVVV
MMAR_4927|M.marinum_M               -----------MG----QFENKVAIVTGAAQGIGQAYADALAREGARVVV
MUL_0478|M.ulcerans_Agy99           -----------MG----QFENKVAIVTGAAQGIGQAYADALAREGARVVV
MAB_1219|M.abscessus_ATCC_1997      -----------MG----EFDNKVAIVTGAAQGIGEAYAHALAREGAAVVV
Mflv_1601|M.gilvum_PYR-GCK          -----------MGLYGDQFNEKVAIVTGAGGGIGQAYAEALAREGAAVVV
Mvan_5156|M.vanbaalenii_PYR-1       -----------MGLYGDQFKEKVAIVTGAGGGIGQAYAEALAREGAAVVV
TH_3037|M.thermoresistible__bu      -----------MG----QFDDKVAIVTGAGGGIGQAYAEALAREGAAVVV
MSMEG_5858|M.smegmatis_MC2_155      -----------MGQYGTNFEDKVAIVTGAGGGIGQAYAEALAREGAAVVV
MAV_0714|M.avium_104                ----------------MRFENKVGIVTGSGGGIGQAYAEALAREGAAVVV
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
                                                      * .:  :***.  *** * *  *. :*  *.*

Mb0792|M.bovis_AF2122/97            ADINADGAAAVAKQIVADGGTVIHVPVDVSDEDSAKAMVDRAVGAFGGID
Rv0769|M.tuberculosis_H37Rv         ADINADGAAAVAKQIVADGGTAIHVPVDVSDEDSAKAMVDRAVGAFGGID
MMAR_4927|M.marinum_M               ADINAEAAEKTAKQIVADGGTAIHVPVDVSDEESARAMADRTVSEFGGID
MUL_0478|M.ulcerans_Agy99           ADINAEAAEKTAKQIVADGGTAIHVPVDVSDEESARAMADRTVSEFGGID
MAB_1219|M.abscessus_ATCC_1997      ADINAEMGEGVAKQIVADGGRAIFAGVDVSDPDSAIAMADKAVSEFGGID
Mflv_1601|M.gilvum_PYR-GCK          ADINVEGAQKVADGIKGEGGNALAVRVDVSDPDSAKEMAAQALSEFGGID
Mvan_5156|M.vanbaalenii_PYR-1       ADINTEGAQKVADGIKGEGGNALAVRVDVSDPESAKGMAAQTLSEFGGID
TH_3037|M.thermoresistible__bu      ADINTEGAQKVADGIKGEGGDALAVPVDVSDPESAEEMAAQTVSEFGGID
MSMEG_5858|M.smegmatis_MC2_155      ADINLEGAQKVADAILGEGGNALAVRVDVSDIDSAKDMAAQTLSEFGGID
MAV_0714|M.avium_104                ADINAEAAEAVAKQIVADGGTAISVAVDVSDPESAKAMADRTLAEFGGID
MLBr_01807|M.leprae_Br4923          THR----ASVVPDWFFG-------VECDVTDNDAIGAAFKAVEEHQGPVE
                                    :.     .  ... : .       .  **:* ::       .    * ::

Mb0792|M.bovis_AF2122/97            YLVNNAAIYGGMKLDLLLTVPLDYYKKFMSVNHDGVLVCTRAVYKHMAKR
Rv0769|M.tuberculosis_H37Rv         YLVNNAAIYGGMKLDLLLTVPLDYYKKFMSVNHDGVLVCTRAVYKHMAKR
MMAR_4927|M.marinum_M               YLVNNAAIYGGMKLDLLLTVPLDYYKKFMSVNHDGVLVCTRAVYKHMAKR
MUL_0478|M.ulcerans_Agy99           YLVNNAAIYGGMKLDLQLTVPLDYYKKFMSVNHDGVLVCTRAVYKHMAKR
MAB_1219|M.abscessus_ATCC_1997      YLVNNAAIYGGMKLDLLLSVPWDYYKKFMSVNQDGALVCTRAVYKHIAQR
Mflv_1601|M.gilvum_PYR-GCK          YLVNNAAIFGGMKLDFLITVDWDYYKKFMSVNLDGALVCTRAVYRKMAKR
Mvan_5156|M.vanbaalenii_PYR-1       YLVNNAAIFGGMKLDFLITVDWDYYKKFMSVNMDGALVCTRAVYRKMAKR
TH_3037|M.thermoresistible__bu      YLVNNAAIFGGMKLDFLITVDWDYYKRFMSVNLDGALVCTRAVYKKMAKR
MSMEG_5858|M.smegmatis_MC2_155      YLVNNAAIFGGMKLDFLLTVDWDYYKKFMSVNLDGALVCTRAVYRKMAKR
MAV_0714|M.avium_104                YLVNNAAIFGGMKLDFLLTIDPEYYKKFMSVNLDGALWCTRAVYKKMTKR
MLBr_01807|M.leprae_Br4923          VLVANAGITSDM---LIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQ
                                     ** **.* ..*   : : :  : :::.:.**  *.:  :: . ::: ::

Mb0792|M.bovis_AF2122/97            GGGAIVNQSSTAAWLYSN---FYGLAKVGVNGLTQQLARELGGMKIRINA
Rv0769|M.tuberculosis_H37Rv         GGGAIVNQSSTAAWLYSN---FYGLAKVGVNGLTQQLARELGGMKIRINA
MMAR_4927|M.marinum_M               GGGAIVNQSSTAAWLYSN---FYGLAKVGVNGLTQQLSRELGGMKIRINA
MUL_0478|M.ulcerans_Agy99           GGGAIVNQSSTAAWLYSN---FYGLAKVGVNGLTQQLSRELGGMKIRINA
MAB_1219|M.abscessus_ATCC_1997      GGGAIVNQSSTAAWLYSG---FYGLAKVGINGLTQQLSRELGGQKIRINA
Mflv_1601|M.gilvum_PYR-GCK          GGGAIVNQSSTAAWLYSN---FYGLAKVGINGLTQQLATELGGQNIRVNA
Mvan_5156|M.vanbaalenii_PYR-1       GGGAIVNQSSTAAWLYSN---FYGLAKVGINGLTQQLATELGGQNIRVNA
TH_3037|M.thermoresistible__bu      GGGAIVNQSSTAAWLYSN---YYGLAKAGLNSLTQQLATELGGQNIRVNA
MSMEG_5858|M.smegmatis_MC2_155      GGGAIVNQSSTAAWLYSN---FYGLAKVGINGLTQQLSRELGGQNIRINA
MAV_0714|M.avium_104                GGGAIVNQSSTAAWLYSN---YYGLAKVGINGLTQQLSRELGGRNIRINA
MLBr_01807|M.leprae_Br4923          RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
                                      *  :  .*...         *. :* *: .:::.*: ***. .*  *.

Mb0792|M.bovis_AF2122/97            IAPGPIDTEATRTVTPAELVKNMVQTIPLSRMGTPEDLVGMCLFLLSDSA
Rv0769|M.tuberculosis_H37Rv         IAPGPIDTEATRTVTPAELVKNMVQTIPLSRMGTPEDLVGMCLFLLSDSA
MMAR_4927|M.marinum_M               IAPGPIDTEATRTVTPGEFVKDMVKQIPLSRMGTPEDLVGMCLFLLGDQA
MUL_0478|M.ulcerans_Agy99           IAPGPIDTEATRTVTPGEFVKDMVKQIPLSRMGTPEDLVGMCLFLLGDQA
MAB_1219|M.abscessus_ATCC_1997      IAPGPTDTEATRGTVPEQFRSELVKNIPLSRMGTVDDMVGMCLFLLSDKA
Mflv_1601|M.gilvum_PYR-GCK          IAPGPIDTEANRTTTPQEMVADIVKGIPLSRMGQPDDLVGMLLFLLSDQA
Mvan_5156|M.vanbaalenii_PYR-1       IAPGPIDTEANRTTTPQEMVADIVKGIPLSRMGEPEDLVGMLLFLLSDQA
TH_3037|M.thermoresistible__bu      IAPGPIDTEANRSTTPKEMVDDIVKRIPLSRLGEPEDLVGMCLFLLSDQA
MSMEG_5858|M.smegmatis_MC2_155      IAPGPIDTEANRTTTPKEMVDDIVKGIPLSRMGQPEDLVGMCLFLLSDQA
MAV_0714|M.avium_104                IAPGPIDTEANRTTTPKEMVDDIVKGLPLSRMGTPDDLVGMCLFLLSDEA
MLBr_01807|M.leprae_Br4923          VAPGFIDTEMTR-AMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDA
                                    :***  *** .* .   :     :: :**.*:*  :::.*   ** .:.*

Mb0792|M.bovis_AF2122/97            SWITGQIFNVDGGQIIRS
Rv0769|M.tuberculosis_H37Rv         SWITGQIFNVDGGQIIRS
MMAR_4927|M.marinum_M               SWITGQIFNVDGGQIIRS
MUL_0478|M.ulcerans_Agy99           SRITGQIFNVDGGQIIRS
MAB_1219|M.abscessus_ATCC_1997      SWITGQVFNVDGGQIIRS
Mflv_1601|M.gilvum_PYR-GCK          KWVTGQIFNVDGGQIIR-
Mvan_5156|M.vanbaalenii_PYR-1       KWITGQIFNVDGGQIIRS
TH_3037|M.thermoresistible__bu      KWITGQIFNVDGGQIIR-
MSMEG_5858|M.smegmatis_MC2_155      RWITGQIFNVDGGQVIRS
MAV_0714|M.avium_104                SWITGQIFNVDGGQIIRS
MLBr_01807|M.leprae_Br4923          GYISGAVIPVDGGLGMGH
                                      ::* :: ****  :