For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_5272 (-)

annotation: anti-anti-sigma factor
coordinates: 5425868 - 5426245
length: 125

MGEQPGDLADPTPFEVGKHQVDQAVVLTVSGEVDMLSSPMLAEAVQTALAAKPAALIVDLSKVGFLASAG
MTVLVTTQAELQPPTKFAVVADGSATSRPIKLMGIDSVLSLYPSLNDALSALSGA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_5272--100% (125)anti-anti-sigma factor
M. avium 104MAV_0435-2e-2146.53% (101) anti-anti-sigma factor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3712c-1e-1446.05% (76) hypothetical protein Mb3712c
M. gilvum PYR-GCKMflv_2021-7e-2550.47% (107) anti-sigma-factor antagonist
M. tuberculosis H37RvRv3687crsfB2e-2039.32% (117) anti-anti-sigma factor RSFB (anti-sigma factor antagonist)
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0214-1e-3661.79% (123) hypothetical protein MMAR_0214
M. smegmatis MC2 155MSMEG_6127-2e-2549.56% (113) anti-anti-sigma factor
M. thermoresistible (build 8)TH_1832-2e-2450.50% (101) ANTI-ANTI-SIGMA FACTOR RSFB (ANTI-SIGMA FACTOR ANTAGONIST)
M. ulcerans Agy99MUL_3602-4e-0731.48% (108) anti sigma factor antagonist
M. vanbaalenii PYR-1Mvan_3003-4e-2546.67% (120) anti-sigma-factor antagonist

CLUSTAL 2.0.9 multiple sequence alignment


Mb3712c|M.bovis_AF2122/97           --------------------------------------------------
Rv3687c|M.tuberculosis_H37Rv        -------------MSAPDSITVTVADHNGVAVLSIGGEIDLITAAALEEA
TH_1832|M.thermoresistible__bu      -----------------------VEHRDDSAVLRVQGVVDLATGDALQQA
MAV_5272|M.avium_104                MGEQP------GDLADPTPFEVGKHQVDQAVVLTVSGEVDMLSSPMLAEA
MMAR_0214|M.marinum_M               MVEQS------GDPTPPTAFGIEKSRVGEAVVVTVSGELDMLTAPRLAEM
MSMEG_6127|M.smegmatis_MC2_155      MTSQ-----------DPANCTVEERRVGDITVVAVTGTVDMLTAPKLEDA
Mvan_3003|M.vanbaalenii_PYR-1       MDEQAAEGTNVGGAASSSTCVVTERWVERTAVVAVSGVVDMLTSPQLESA
Mflv_2021|M.gilvum_PYR-GCK          ------------------MQQFTEREVDGVVIVAAVGAIDMLTAPQLQEA
MUL_3602|M.ulcerans_Agy99           ----------------MDLLAVEHEVRQDTVVVRAKGDVDSSTVEQLVVH
                                                                                      

Mb3712c|M.bovis_AF2122/97           ----MADNPTA----LVIDLSAVEFLGSVGLKILAATSEK-IGQSVKFGV
Rv3687c|M.tuberculosis_H37Rv        IGEVVADNPTA----LVIDLSAVEFLGSVGLKILAATSEK-IGQSVKFGV
TH_1832|M.thermoresistible__bu      IDDLIATRPSA----LVVDLSAVDFLASVGLQILVATHER-LSPSARFAV
MAV_5272|M.avium_104                VQTALAAKPAA----LIVDLSKVGFLASAGMTVLVTTQAE-LQPPTKFAV
MMAR_0214|M.marinum_M               LRTSLIEAPAT----LIVDLSKVDFLASAGMTVLVSAKAQ-AVAPTRFVV
MSMEG_6127|M.smegmatis_MC2_155      IGSAAKSEPSA----VVVDLSAVDFLASAGMGVLVAAHGE-LAPAVRLVV
Mvan_3003|M.vanbaalenii_PYR-1       IDTALSQQPAA----VVIDFTDVEFLASAGMGVLVAAHDK-AGSDVKISV
Mflv_2021|M.gilvum_PYR-GCK          VAAAARRRPSG----LVVDLTSVDFLGSAGMQVLMETRKG-LDGDTRFAV
MUL_3602|M.ulcerans_Agy99           LAAAMQLAATHPARLVVIDLQPVTFFGSAGLNAVLECHEQGMAAGTSVRL
                                            .:     :::*:  * *:.*.*:  :           . . :

Mb3712c|M.bovis_AF2122/97           VARGSVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
Rv3687c|M.tuberculosis_H37Rv        VARGSVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
TH_1832|M.thermoresistible__bu      VADGPATSRPIQLTRLDEVIALYPTLDEALSGVRTGERAE-------
MAV_5272|M.avium_104                VADGSATSRPIKLMGIDSVLSLYPSLNDALSALSGA-----------
MMAR_0214|M.marinum_M               VADGPATSRPIRLMGIDAMLPLYDALDDALNDISDS-----------
MSMEG_6127|M.smegmatis_MC2_155      VADGPATSRPLKLVGIADVVDLFATLDEALSSLKT------------
Mvan_3003|M.vanbaalenii_PYR-1       VAEGPATSRPLKLVGIADIVALYPNLEEALAARDT------------
Mflv_2021|M.gilvum_PYR-GCK          VADGPATSRPLKITGITDYVDLYPSLDVALADLAG------------
MUL_3602|M.ulcerans_Agy99           VADHGQLLAPIQVTELDRIFEIYPTLAGALRPGKPGEHDLEDVERPR
                                    **       *:::  :   . ::  *  **