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DEQAAEGTNVGGAASSSTCVVTERWVERTAVVAVSGVVDMLTSPQLESAIDTALSQQPAAVVIDFTDVEF LASAGMGVLVAAHDKAGSDVKISVVAEGPATSRPLKLVGIADIVALYPNLEEALAARDT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3003 | - | - | 100% (130) | anti-sigma-factor antagonist |
| M. vanbaalenii PYR-1 | Mvan_4702 | - | 3e-25 | 54.37% (103) | anti-sigma-factor antagonist |
| M. vanbaalenii PYR-1 | Mvan_1481 | - | 2e-20 | 45.92% (98) | anti-sigma-factor antagonist |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3712c | - | 2e-11 | 42.25% (71) | hypothetical protein Mb3712c |
| M. gilvum PYR-GCK | Mflv_3284 | - | 1e-56 | 86.15% (130) | anti-sigma-factor antagonist |
| M. tuberculosis H37Rv | Rv3687c | rsfB | 3e-17 | 41.05% (95) | anti-anti-sigma factor RSFB (anti-sigma factor antagonist) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5181 | - | 3e-21 | 41.96% (112) | anti-anti-sigma regulatory factor |
| M. avium 104 | MAV_5272 | - | 4e-25 | 46.67% (120) | anti-anti-sigma factor |
| M. smegmatis MC2 155 | MSMEG_6127 | - | 1e-31 | 59.29% (113) | anti-anti-sigma factor |
| M. thermoresistible (build 8) | TH_0498 | - | 2e-33 | 62.62% (107) | anti-anti-sigma factor |
| M. ulcerans Agy99 | MUL_3602 | - | 4e-06 | 32.04% (103) | anti sigma factor antagonist |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3712c|M.bovis_AF2122/97 --------------------------------------------------
Rv3687c|M.tuberculosis_H37Rv MSAPDSIT-----------VTVADH--NGVAVLSIGGEIDLITAA----A
MMAR_5181|M.marinum_M MSAPDSIT-----------AVVTDH--DGVTVLSIGGEIDLVTAP----A
Mvan_3003|M.vanbaalenii_PYR-1 MDEQAAEGTNVGGAASSSTCVVTERWVERTAVVAVSGVVDMLTSP----Q
Mflv_3284|M.gilvum_PYR-GCK MDEQAAEGTAAGGAP-SSTCVVTQRWVDTTAVVAVTGVVDMLTSP----Q
TH_0498|M.thermoresistible__bu --------------------VIDERWDADIAVVSATGVVDMLSAP----Q
MSMEG_6127|M.smegmatis_MC2_155 MTSQDPAN-----------CTVEERRVGDITVVAVTGTVDMLTAP----K
MAV_5272|M.avium_104 MGEQPGDLADP------TPFEVGKHQVDQAVVLTVSGEVDMLSSP----M
MUL_3602|M.ulcerans_Agy99 ----------------MDLLAVEHEVRQDTVVVRAKGDVDSSTVEQLVVH
Mb3712c|M.bovis_AF2122/97 --------MADNPTALVIDLSAVEFLGSVGLKILAATSEK-IGQSVKFGV
Rv3687c|M.tuberculosis_H37Rv LEEAIGEVVADNPTALVIDLSAVEFLGSVGLKILAATSEK-IGQSVKFGV
MMAR_5181|M.marinum_M LEEAIGAVVADSPTALVIDLSGVEFLGSVGLKILAATYEK-LGTAAEFGV
Mvan_3003|M.vanbaalenii_PYR-1 LESAIDTALSQQPAAVVIDFTDVEFLASAGMGVLVAAHDK-AGSDVKISV
Mflv_3284|M.gilvum_PYR-GCK LETAIDDALNQKPGAVVIDFTEVEFLASAGMGVLVAAHDK-AGSEVKISV
TH_0498|M.thermoresistible__bu LDEAIRTALGKKPRALVVDFTAVDFLASAGMGVLVAIHDE-VSPAVNLTI
MSMEG_6127|M.smegmatis_MC2_155 LEDAIGSAAKSEPSAVVVDLSAVDFLASAGMGVLVAAHGE-LAPAVRLVV
MAV_5272|M.avium_104 LAEAVQTALAAKPAALIVDLSKVGFLASAGMTVLVTTQAE-LQPPTKFAV
MUL_3602|M.ulcerans_Agy99 LAAAMQLAATHPARLVVIDLQPVTFFGSAGLNAVLECHEQGMAAGTSVRL
. :::*: * *:.*.*: : : . . :
Mb3712c|M.bovis_AF2122/97 VARGSVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
Rv3687c|M.tuberculosis_H37Rv VARGSVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
MMAR_5181|M.marinum_M VAQGPATRRPIHLTGLDKTFPLYPALDDALTGVRDGKLNR-------
Mvan_3003|M.vanbaalenii_PYR-1 VAEGPATSRPLKLVGIADIVALYPNLEEALAARDT------------
Mflv_3284|M.gilvum_PYR-GCK VADGPATSRPLKLVGIADIVALYSNLDEALAARDT------------
TH_0498|M.thermoresistible__bu VADGPATSRPLKLLGIADLVPLHATLDEALAAVAT------------
MSMEG_6127|M.smegmatis_MC2_155 VADGPATSRPLKLVGIADVVDLFATLDEALSSLKT------------
MAV_5272|M.avium_104 VADGSATSRPIKLMGIDSVLSLYPSLNDALSALSGA-----------
MUL_3602|M.ulcerans_Agy99 VADHGQLLAPIQVTELDRIFEIYPTLAGALRPGKPGEHDLEDVERPR
** *::: : . :.. * **