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M. gilvum PYR-GCK Mflv_2021 (-)

annotation: anti-sigma-factor antagonist
coordinates: 2100487 - 2100825
length: 112

VQQFTEREVDGVVIVAAVGAIDMLTAPQLQEAVAAAARRRPSGLVVDLTSVDFLGSAGMQVLMETRKGLD
GDTRFAVVADGPATSRPLKITGITDYVDLYPSLDVALADLAG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2021--100% (112)anti-sigma-factor antagonist
M. gilvum PYR-GCKMflv_3284-3e-2550.96% (104) anti-sigma-factor antagonist
M. gilvum PYR-GCKMflv_4938-1e-1439.05% (105) anti-sigma-factor antagonist

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3712c-4e-1037.50% (72) hypothetical protein Mb3712c
M. tuberculosis H37RvRv3687crsfB3e-1635.19% (108) anti-anti-sigma factor RSFB (anti-sigma factor antagonist)
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0214-8e-2248.54% (103) hypothetical protein MMAR_0214
M. avium 104MAV_5272-5e-2550.47% (107) anti-anti-sigma factor
M. smegmatis MC2 155MSMEG_6127-1e-2755.24% (105) anti-anti-sigma factor
M. thermoresistible (build 8)TH_0498-3e-2450.94% (106) anti-anti-sigma factor
M. ulcerans Agy99MUL_3602-7e-0937.04% (108) anti sigma factor antagonist
M. vanbaalenii PYR-1Mvan_4702-1e-4475.89% (112) anti-sigma-factor antagonist

CLUSTAL 2.0.9 multiple sequence alignment


Mb3712c|M.bovis_AF2122/97           ------------------------------------------------MA
Rv3687c|M.tuberculosis_H37Rv        -------MSAPDSITVTVADHNGVAVLSIGGEIDLITAAALEEAIGEVVA
Mflv_2021|M.gilvum_PYR-GCK          ------------MQQFTEREVDGVVIVAAVGAIDMLTAPQLQEAVAAAAR
Mvan_4702|M.vanbaalenii_PYR-1       ------------MQQFTEHQIDGVLVVAAVGAVDMLTAPQLQEAINAALD
MSMEG_6127|M.smegmatis_MC2_155      -----MTSQDPANCTVEERRVGDITVVAVTGTVDMLTAPKLEDAIGSAAK
TH_0498|M.thermoresistible__bu      --------------VIDERWDADIAVVSATGVVDMLSAPQLDEAIRTALG
MMAR_0214|M.marinum_M               MVEQSGDPTPPTAFGIEKSRVGEAVVVTVSGELDMLTAPRLAEMLRTSLI
MAV_5272|M.avium_104                MGEQPGDLADPTPFEVGKHQVDQAVVLTVSGEVDMLSSPMLAEAVQTALA
MUL_3602|M.ulcerans_Agy99           ----------MDLLAVEHEVRQDTVVVRAKGDVDSSTVEQLVVHLAAAMQ
                                                                                      

Mb3712c|M.bovis_AF2122/97           DNPTA----LVIDLSAVEFLGSVGLKILAATSEK-IGQSVKFGVVARGSV
Rv3687c|M.tuberculosis_H37Rv        DNPTA----LVIDLSAVEFLGSVGLKILAATSEK-IGQSVKFGVVARGSV
Mflv_2021|M.gilvum_PYR-GCK          RRPSG----LVVDLTSVDFLGSAGMQVLMETRKG-LDGDTRFAVVADGPA
Mvan_4702|M.vanbaalenii_PYR-1       RQPTG----VVVDLTAVDFLGSAGMQVLMTTRRQ-LEGTVKFAVVADGPA
MSMEG_6127|M.smegmatis_MC2_155      SEPSA----VVVDLSAVDFLASAGMGVLVAAHGE-LAPAVRLVVVADGPA
TH_0498|M.thermoresistible__bu      KKPRA----LVVDFTAVDFLASAGMGVLVAIHDE-VSPAVNLTIVADGPA
MMAR_0214|M.marinum_M               EAPAT----LIVDLSKVDFLASAGMTVLVSAKAQ-AVAPTRFVVVADGPA
MAV_5272|M.avium_104                AKPAA----LIVDLSKVGFLASAGMTVLVTTQAE-LQPPTKFAVVADGSA
MUL_3602|M.ulcerans_Agy99           LAATHPARLVVIDLQPVTFFGSAGLNAVLECHEQGMAAGTSVRLVADHGQ
                                      .      :::*:  * *:.*.*:  :           . . :**    

Mb3712c|M.bovis_AF2122/97           TRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
Rv3687c|M.tuberculosis_H37Rv        TRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
Mflv_2021|M.gilvum_PYR-GCK          TSRPLKITGITDYVDLYPSLDVALADLAG------------
Mvan_4702|M.vanbaalenii_PYR-1       TSRPLKITGIADYVDLFSTLDVALRNLAG------------
MSMEG_6127|M.smegmatis_MC2_155      TSRPLKLVGIADVVDLFATLDEALSSLKT------------
TH_0498|M.thermoresistible__bu      TSRPLKLLGIADLVPLHATLDEALAAVAT------------
MMAR_0214|M.marinum_M               TSRPIRLMGIDAMLPLYDALDDALNDISDS-----------
MAV_5272|M.avium_104                TSRPIKLMGIDSVLSLYPSLNDALSALSGA-----------
MUL_3602|M.ulcerans_Agy99           LLAPIQVTELDRIFEIYPTLAGALRPGKPGEHDLEDVERPR
                                       *:::  :   . :. :*  **