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M. gilvum PYR-GCK Mflv_4938 (-)

annotation: anti-sigma-factor antagonist
coordinates: 5258838 - 5259215
length: 125

MMISTDQTRSGKFTVTPRRDGDLLVLHVTGDLDVLTAPTLSTHLDIALADAPPVVIVDISDVSFLSSAGI
GLLVETHRLTERGGISLRVVADGAATSRPLRMMRIDEVIDLYATTDEAKAGRPA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4938--100% (125)anti-sigma-factor antagonist
M. gilvum PYR-GCKMflv_3284-1e-1943.48% (115) anti-sigma-factor antagonist
M. gilvum PYR-GCKMflv_2021-1e-1439.05% (105) anti-sigma-factor antagonist

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3712c-2e-0836.84% (76) hypothetical protein Mb3712c
M. tuberculosis H37RvRv3687crsfB4e-1334.55% (110) anti-anti-sigma factor RSFB (anti-sigma factor antagonist)
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0214-1e-1842.86% (119) hypothetical protein MMAR_0214
M. avium 104MAV_5272-2e-1641.51% (106) anti-anti-sigma factor
M. smegmatis MC2 155MSMEG_6127-2e-2150.48% (105) anti-anti-sigma factor
M. thermoresistible (build 8)TH_0498-2e-1842.45% (106) anti-anti-sigma factor
M. ulcerans Agy99MUL_3602-1e-1032.71% (107) anti sigma factor antagonist
M. vanbaalenii PYR-1Mvan_1481-4e-4171.43% (119) anti-sigma-factor antagonist

CLUSTAL 2.0.9 multiple sequence alignment


Mb3712c|M.bovis_AF2122/97           ------------------------------------------------MA
Rv3687c|M.tuberculosis_H37Rv        -------MSAPDSITVTVADHNGVAVLSIGGEIDLITAAALEEAIGEVVA
Mflv_4938|M.gilvum_PYR-GCK          MMMISTDQTRSGKFTVTPRRDGDLLVLHVTGDLDVLTAPTLSTHLDIALA
Mvan_1481|M.vanbaalenii_PYR-1       --MDVSGHGRSRGFSVSPDRQGAALVLRVTGDLDAMTAPTLVTHLDIALA
MSMEG_6127|M.smegmatis_MC2_155      MTSQ-----DPANCTVEERRVGDITVVAVTGTVDMLTAPKLEDAIGSAAK
TH_0498|M.thermoresistible__bu      --------------VIDERWDADIAVVSATGVVDMLSAPQLDEAIRTALG
MMAR_0214|M.marinum_M               MVEQSGDPTPPTAFGIEKSRVGEAVVVTVSGELDMLTAPRLAEMLRTSLI
MAV_5272|M.avium_104                MGEQPGDLADPTPFEVGKHQVDQAVVLTVSGEVDMLSSPMLAEAVQTALA
MUL_3602|M.ulcerans_Agy99           ----------MDLLAVEHEVRQDTVVVRAKGDVDSSTVEQLVVHLAAAMQ
                                                                                      

Mb3712c|M.bovis_AF2122/97           DNP----TALVIDLSAVEFLGSVGLKILAATSEKIGQS-VKFGVVARGSV
Rv3687c|M.tuberculosis_H37Rv        DNP----TALVIDLSAVEFLGSVGLKILAATSEKIGQS-VKFGVVARGSV
Mflv_4938|M.gilvum_PYR-GCK          DAP----PVVIVDISDVSFLSSAGIGLLVETHRLTERGGISLRVVADGAA
Mvan_1481|M.vanbaalenii_PYR-1       DAP----PVVVVDMTDVEFLSSAGISVLVETHRLAERADISLRVVADGPA
MSMEG_6127|M.smegmatis_MC2_155      SEP----SAVVVDLSAVDFLASAGMGVLVAAHGELAPA-VRLVVVADGPA
TH_0498|M.thermoresistible__bu      KKP----RALVVDFTAVDFLASAGMGVLVAIHDEVSPA-VNLTIVADGPA
MMAR_0214|M.marinum_M               EAP----ATLIVDLSKVDFLASAGMTVLVSAKAQAVAP-TRFVVVADGPA
MAV_5272|M.avium_104                AKP----AALIVDLSKVGFLASAGMTVLVTTQAELQPP-TKFAVVADGSA
MUL_3602|M.ulcerans_Agy99           LAATHPARLVVIDLQPVTFFGSAGLNAVLECHEQGMAAGTSVRLVADHGQ
                                      .      :::*:  * *:.*.*:  :             . :**    

Mb3712c|M.bovis_AF2122/97           TRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
Rv3687c|M.tuberculosis_H37Rv        TRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
Mflv_4938|M.gilvum_PYR-GCK          TSRPLRMMRIDEVIDLYATTDEAK----AGRPA--------
Mvan_1481|M.vanbaalenii_PYR-1       TSRPFRMMRLDEVIDLYPTLADAMGERQQGRPPT-------
MSMEG_6127|M.smegmatis_MC2_155      TSRPLKLVGIADVVDLFATLDEALSSLKT------------
TH_0498|M.thermoresistible__bu      TSRPLKLLGIADLVPLHATLDEALAAVAT------------
MMAR_0214|M.marinum_M               TSRPIRLMGIDAMLPLYDALDDALNDISDS-----------
MAV_5272|M.avium_104                TSRPIKLMGIDSVLSLYPSLNDALSALSGA-----------
MUL_3602|M.ulcerans_Agy99           LLAPIQVTELDRIFEIYPTLAGALRPGKPGEHDLEDVERPR
                                       *:::  :   . :. :   *