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MNLMRIVVRRLGTAAVTALLVCGLITVTGGATAGAYSRPGLPVETLMVPSAAMGRDIPVKFQGGGPRAVY LLDGLRARDDNSGWDIETAAFETFFESGLSVVMPVGGMSSFYTNWQGPAVGNGGTHNYQWETFLTSELPA YLAANKGISPSGNAVVGLSMSGSAALIMAAYHPGQFSYAGSLSGYLNLSEGVWPLLVGIAMRDAGGFSAT SMWGLGGSAAWKRNDPTVNVGKLVANGTRIWVYCGTGRPGELGGGGDVPGQLLEAITLDSNREFQRQYQS AGGSNGVFNFPPNGTHGWGYWGSQLNAMKPDIQRVLGA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3241 | - | - | 100% (318) | putative esterase |
| M. gilvum PYR-GCK | Mflv_1164 | - | e-121 | 64.40% (323) | putative esterase |
| M. gilvum PYR-GCK | Mflv_3335 | - | e-117 | 63.64% (319) | putative esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0134c | fbpC | 1e-120 | 65.37% (309) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. tuberculosis H37Rv | Rv0129c | fbpC | 1e-120 | 65.37% (309) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. leprae Br4923 | MLBr_02655 | fbpC2 | 1e-114 | 61.36% (308) | secreted antigen 85A, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_0176 | - | 1e-103 | 56.92% (318) | antigen 85-A precursor |
| M. marinum M | MMAR_0328 | fbpC | 1e-116 | 63.75% (309) | secreted antigen 85-C FbpC |
| M. avium 104 | MAV_5183 | - | 1e-117 | 63.43% (309) | antigen 85-C |
| M. smegmatis MC2 155 | MSMEG_6583 | - | 1e-121 | 63.90% (313) | antigen 85-C |
| M. thermoresistible (build 8) | TH_1961 | fbpA | 1e-123 | 69.01% (313) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_4793 | fbpC | 1e-116 | 63.75% (309) | secreted antigen 85-C FbpC |
| M. vanbaalenii PYR-1 | Mvan_2954 | - | 1e-168 | 87.77% (319) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3241|M.gilvum_PYR-GCK MNLMRIVVRR--LGTAAVT-------------ALLVCGLITVTGG-ATAG
Mvan_2954|M.vanbaalenii_PYR-1 MEPIRDLIRR--MAVGAVT-------------ALLLSGLIAVAGASAPAG
TH_1961|M.thermoresistible__bu MNQVKMSGQEKAMNFSAKPRRNGSYRHWFRRLGAVIAALVLLPALTAVVG
MMAR_0328|M.marinum_M MKFVEKLR---GAAAGAPRRLTIAAIG-----AALLSGLVGAVGGAATAG
MUL_4793|M.ulcerans_Agy99 MKFVEKLR---GAAAGAPRRLTIAAIG-----AALLSGLVGAVGGAATAG
Mb0134c|M.bovis_AF2122/97 MTFFEQVRRLRSAATTLPRRLAIAAMG-----AVLVYGLVGTFGGPATAG
Rv0129c|M.tuberculosis_H37Rv MTFFEQVRRLRSAATTLPRRLAIAAMG-----AVLVYGLVGTFGGPATAG
MLBr_02655|M.leprae_Br4923 MKFLQQMRKLFGLAAKFPARLTIAVIG-----TALLAGLVGVVGDTAIAV
MAV_5183|M.avium_104 MSFIEKVRKLRGAAATMPRRLAIAAVG-----ASLLSGVAVAAGGSPVAG
MSMEG_6583|M.smegmatis_MC2_155 ------MKP--SFFSTLSRRVAAGAAT-----VLMLAGLI-ATGPVPQAA
MAB_0176|M.abscessus_ATCC_1997 MKLFSKMRG--ALARQSARRIAVAATA--VAVLPGVAGIVGGTALTPVAG
: .: . . .
Mflv_3241|M.gilvum_PYR-GCK AYSRPGLPVETLMVPSAAMGRDIPVKFQGGGPRAVYLLDGLRARDDNSGW
Mvan_2954|M.vanbaalenii_PYR-1 AYSRPGLPVETLMVPSAAMGRDIPVKFQGGGPRAVYLLDGMRARDDNSGW
TH_1961|M.thermoresistible__bu AMPRAQAAPETLMVPSPSMGRDIPVQFQGGGEKAVYLLDGMRARDDRNGW
MMAR_0328|M.marinum_M AFSRPGLPVEYLQIPSAAMGRDIKVQFQGGGAHSVYLLDGLRAQDDYNGW
MUL_4793|M.ulcerans_Agy99 AFSRPGLPVEYLQIPSAAMGRDIKVQFQGGGAHSVYLLDGLRAQDDYNGW
Mb0134c|M.bovis_AF2122/97 AFSRPGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGW
Rv0129c|M.tuberculosis_H37Rv AFSRPGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGW
MLBr_02655|M.leprae_Br4923 AFSKPGLPVEYLQVPSPSMGHDIKIQFQGGGQHAVYLLDGLRAQEDYNGW
MAV_5183|M.avium_104 AFSKPGLPVEYLEVPSPSMGRNIKVQFQGGGPHAVYLLDGLRAQDDYNGW
MSMEG_6583|M.smegmatis_MC2_155 AYSRDGLPVERLQVPSAAMGRDITVQFQGGGPHALYLLDGLRAQDDANGW
MAB_0176|M.abscessus_ATCC_1997 AFSRPGLPVEYLQVPSASMGREIKVQFQPGGAKAVYLLDGLRARDDFSGW
* .: . * * :**.:**::* ::** ** :::*****:**::* .**
Mflv_3241|M.gilvum_PYR-GCK DIETAAFETFFESGLSVVMPVGGMSSFYTNWQGPAVGNGGTHNYQWETFL
Mvan_2954|M.vanbaalenii_PYR-1 DIETNAFETFFESGLSVVMPVGGMSSFYTNWRGPATGNGTTYNYQWETFL
TH_1961|M.thermoresistible__bu DIETGAFSWFEGSGLSVVAPVGGMSSFYTDWYGPAVGNGRTQTYKWETFL
MMAR_0328|M.marinum_M DINTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFL
MUL_4793|M.ulcerans_Agy99 DINTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFL
Mb0134c|M.bovis_AF2122/97 DINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFL
Rv0129c|M.tuberculosis_H37Rv DINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFL
MLBr_02655|M.leprae_Br4923 DINTPAFEEYYHSGLSVIMPVGGQSSFYSNWYQPSQGNGQHYTYKWETFL
MAV_5183|M.avium_104 DINTPAFEEFYQSGLSVIMPVGGQSSFYSNWYQPSSGNGQNYTYKWETFL
MSMEG_6583|M.smegmatis_MC2_155 DINTAAFEWFYQSGISVVMPVGGQSSFYTDWYRPAVGSAGTTTYKWETFL
MAB_0176|M.abscessus_ATCC_1997 DIETTAFEDYYQSGISMVMPVGGQSSFYTDWYNPAKGKDGVWTYKWETFT
**:* **. : **:*:: **** ****::* *: .. .*:****
Mflv_3241|M.gilvum_PYR-GCK TSELPAYLAANKGISPSGNAVVGLSMSGSAALIMAAYHPGQFSYAGSLSG
Mvan_2954|M.vanbaalenii_PYR-1 TSELPAYLAANKGISPSGNAVVGLSMSGSAALILAAYHPGQFSYAGSLSG
TH_1961|M.thermoresistible__bu TSELPAWLAENRGVSPSGNAVVGVSMSGSSALILAAYHPGQFSYAGSLSG
MMAR_0328|M.marinum_M TREMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSG
MUL_4793|M.ulcerans_Agy99 TREMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSG
Mb0134c|M.bovis_AF2122/97 TREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSG
Rv0129c|M.tuberculosis_H37Rv TREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSG
MLBr_02655|M.leprae_Br4923 TQEMPSWLQANKNVLPTGNAAVGLSMSGSSALILASYYPQQFPYAASLSG
MAV_5183|M.avium_104 TQEMPLWMQSNKQVSPAGNAAVGLSMSGGSALILAAYYPQQFPYAASLSG
MSMEG_6583|M.smegmatis_MC2_155 TRELPAWLAANRGVEPTGNAVVGLSMSGGAALNLATWYPQQFIFAGALSG
MAB_0176|M.abscessus_ATCC_1997 TQELPAYLAANKGISQTGNAVVGLSMGASAALTLSIYHPQLFVYAGALSG
* *:* :: *: : :***.**:**...:** :: ::* * :*.:***
Mflv_3241|M.gilvum_PYR-GCK YLNLSEGVWPLLVGIAMRDAGGFSATSMWGLGGSAAWKRNDPTVNVGKLV
Mvan_2954|M.vanbaalenii_PYR-1 YLNLSDGVWPLLVSIAMRDAGGFSSTAMWGLGGGPAWQRNDPTVNVGRLV
TH_1961|M.thermoresistible__bu YLNLSEDYWPLLIAVAMADAGGFNALDMWGPYGGPAWQRNDPMLQVGRLV
MMAR_0328|M.marinum_M FLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLV
MUL_4793|M.ulcerans_Agy99 FLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLV
Mb0134c|M.bovis_AF2122/97 FLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLV
Rv0129c|M.tuberculosis_H37Rv FLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLV
MLBr_02655|M.leprae_Br4923 FLNPSEGWWPTMIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLV
MAV_5183|M.avium_104 FLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLV
MSMEG_6583|M.smegmatis_MC2_155 FLNPSQGLWPTMIGFAMKDAGGYNSADMWGLANDPAWRRNDPMVNINRLV
MAB_0176|M.abscessus_ATCC_1997 FLNPSD--MKFQIGLAMGDAGGFSASDMWGPDSDPAWQRNDPFLNIQKII
:** *: :..** *:**:.: *** ..**:**** ::: :::
Mflv_3241|M.gilvum_PYR-GCK ANGTRIWVYCGTGRPGELGGGG----DVPGQLLEAITLDSNREFQRQYQS
Mvan_2954|M.vanbaalenii_PYR-1 ANGTRIWVYCGTGRPGELGGGG----DVPGQVLEAITLDSNREFQRRYQA
TH_1961|M.thermoresistible__bu ANGTRIWVYTGNGNPTELDAGLG-DAQIPAQFLEGLTVRTSREFQRAYQR
MMAR_0328|M.marinum_M ANNTRIWVYCGNGTPSDLG-----GDNMPAKFLEGLTLRTNQTFRDTYLA
MUL_4793|M.ulcerans_Agy99 ANNTRIWVYCGNGTPSDLG-----GDNMPAKFLEGLTLRTNQTFRDTYLA
Mb0134c|M.bovis_AF2122/97 ANNTRIWVYCGNGTPSDLG-----GDNIPAKFLEGLTLRTNQTFRDTYAA
Rv0129c|M.tuberculosis_H37Rv ANNTRIWVYCGNGTPSDLG-----GDNIPAKFLEGLTLRTNQTFRDTYAA
MLBr_02655|M.leprae_Br4923 ANNTRIWVYCGNGAPNELG-----GDNIPAKFLESLTLSTNEIFQNTYAA
MAV_5183|M.avium_104 ANNTRIWVYCGNGTPSDLG-----GDNVPAKFLEGLTLRTNEQFQNNYAA
MSMEG_6583|M.smegmatis_MC2_155 ANNTAIWVYCGNGAPSDLDAAGDFGQLYSAQFLENITVNTNKEFQKRYLA
MAB_0176|M.abscessus_ATCC_1997 DNGTRLWIYCGTGDSTDLDATRNGFENFTGGFLEGMAIGSNKKFVEAYTA
*.* :*:* *.* . :*. .. .** ::: :.. * *
Mflv_3241|M.gilvum_PYR-GCK AGGSNGVFNFPPNGTHGWGYWGSQLNAMKPDIQRVL--GA----------
Mvan_2954|M.vanbaalenii_PYR-1 AGGGNGVFNFPPDGTHGWGYWGAQLGAMKPDIQRVL--GA----------
TH_1961|M.thermoresistible__bu AGGTNAVFNFPASGTHSWGYWGGQLQAMIPDIQRTL--GAAPAE------
MMAR_0328|M.marinum_M SGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVL-NGPAVPAAPAA--
MUL_4793|M.ulcerans_Agy99 SGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVL-NGPAVPAAPAA--
Mb0134c|M.bovis_AF2122/97 DGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVL-NGATPPAAPAA--
Rv0129c|M.tuberculosis_H37Rv DGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVL-NGATPPAAPAA--
MLBr_02655|M.leprae_Br4923 SGGRNGVFNFPPNGTHSWPYWNQQLVAMKPDIQQIL-NGSNNNA------
MAV_5183|M.avium_104 AGGRNGVFNFPANGTHSWPYWNQQLMAMKPDMQQVL-LSGNTTAAPAQ--
MSMEG_6583|M.smegmatis_MC2_155 AGGHNAVFNFPPNGTHAWGYWGAQLQAMKPDLLRVLGVGAPAPAAPAAPA
MAB_0176|M.abscessus_ATCC_1997 AGGKNAHIEFPPGGIHNWTYWGQQLRAMKPDMVAYL--QSH---------
** *. ::**..* * * **. ** ** *: *
Mflv_3241|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2954|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1961|M.thermoresistible__bu --------------------------------------------------
MMAR_0328|M.marinum_M -----PEAPAAPVAPAA---------------------------------
MUL_4793|M.ulcerans_Agy99 -----PEAPAAPVAPAA---------------------------------
Mb0134c|M.bovis_AF2122/97 -----PAA------------------------------------------
Rv0129c|M.tuberculosis_H37Rv -----PAA------------------------------------------
MLBr_02655|M.leprae_Br4923 --------------------------------------------------
MAV_5183|M.avium_104 -----PAQPAQPAQPAQPAQPAT---------------------------
MSMEG_6583|M.smegmatis_MC2_155 PAAPVPAAPGMPVAPVAPAVPGAQGLPAAPAYPVAPGVQGVPGVQGVPAA
MAB_0176|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3241|M.gilvum_PYR-GCK --------------
Mvan_2954|M.vanbaalenii_PYR-1 --------------
TH_1961|M.thermoresistible__bu --------------
MMAR_0328|M.marinum_M --------------
MUL_4793|M.ulcerans_Agy99 --------------
Mb0134c|M.bovis_AF2122/97 --------------
Rv0129c|M.tuberculosis_H37Rv --------------
MLBr_02655|M.leprae_Br4923 --------------
MAV_5183|M.avium_104 --------------
MSMEG_6583|M.smegmatis_MC2_155 PASPAVALPATRPV
MAB_0176|M.abscessus_ATCC_1997 --------------