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VKPSFFSTLSRRVAAGAATVLMLAGLIATGPVPQAAAYSRDGLPVERLQVPSAAMGRDITVQFQGGGPHA LYLLDGLRAQDDANGWDINTAAFEWFYQSGISVVMPVGGQSSFYTDWYRPAVGSAGTTTYKWETFLTREL PAWLAANRGVEPTGNAVVGLSMSGGAALNLATWYPQQFIFAGALSGFLNPSQGLWPTMIGFAMKDAGGYN SADMWGLANDPAWRRNDPMVNINRLVANNTAIWVYCGNGAPSDLDAAGDFGQLYSAQFLENITVNTNKEF QKRYLAAGGHNAVFNFPPNGTHAWGYWGAQLQAMKPDLLRVLGVGAPAPAAPAAPAPAAPVPAAPGMPVA PVAPAVPGAQGLPAAPAYPVAPGVQGVPGVQGVPAAPASPAVALPATRPV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6583 | - | - | 100% (400) | antigen 85-C |
| M. smegmatis MC2 155 | MSMEG_3580 | - | e-130 | 69.11% (314) | antigen 85-C |
| M. smegmatis MC2 155 | MSMEG_2078 | - | e-118 | 64.58% (319) | antigen 85-C |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0134c | fbpC | 1e-130 | 67.37% (331) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. gilvum PYR-GCK | Mflv_5146 | - | 1e-138 | 67.16% (335) | putative esterase |
| M. tuberculosis H37Rv | Rv0129c | fbpC | 1e-130 | 67.37% (331) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. leprae Br4923 | MLBr_02655 | fbpC2 | 1e-119 | 63.46% (312) | secreted antigen 85A, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_0176 | - | 1e-108 | 58.68% (317) | antigen 85-A precursor |
| M. marinum M | MMAR_0328 | fbpC | 1e-130 | 67.36% (337) | secreted antigen 85-C FbpC |
| M. avium 104 | MAV_5183 | - | 1e-128 | 62.29% (350) | antigen 85-C |
| M. thermoresistible (build 8) | TH_1495 | fbpA | 1e-147 | 71.05% (342) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_4793 | fbpC | 1e-130 | 67.36% (337) | secreted antigen 85-C FbpC |
| M. vanbaalenii PYR-1 | Mvan_1190 | - | 1e-144 | 69.32% (339) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02655|M.leprae_Br4923 MKFLQQMRKLFGLAAKFPARLTIAVIGTALLAGLVGVVGD---TAIAVAF
MAV_5183|M.avium_104 MSFIEKVRKLRGAAATMPRRLAIAAVGASLLSGVAVAAGG---SPVAGAF
Mb0134c|M.bovis_AF2122/97 MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGG---PATAGAF
Rv0129c|M.tuberculosis_H37Rv MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGG---PATAGAF
MMAR_0328|M.marinum_M MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGG---AATAGAF
MUL_4793|M.ulcerans_Agy99 MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGG---AATAGAF
MAB_0176|M.abscessus_ATCC_1997 MKLFSKMRG--ALARQSARRIAVAATAVAVLPGVAGIVGGTALTPVAGAF
Mflv_5146|M.gilvum_PYR-GCK -----------------MTFFARIAVAVLLAAGLLTVAP----SPQAAAF
Mvan_1190|M.vanbaalenii_PYR-1 -----------------MTFFARIAAAVLLAAGLLTAGA----APQAQAF
TH_1495|M.thermoresistible__bu --------VANRVAGRAVSDLMRAIGVLLLVLPVTVAVVNR--APVAAAY
MSMEG_6583|M.smegmatis_MC2_155 --------MKPSFFSTLSRRVAAGAATVLMLAGLIATGP----VPQAAAY
. : : . * *:
MLBr_02655|M.leprae_Br4923 SKPGLPVEYLQVPSPSMGHDIKIQFQGGGQHAVYLLDGLRAQEDYNGWDI
MAV_5183|M.avium_104 SKPGLPVEYLEVPSPSMGRNIKVQFQGGGPHAVYLLDGLRAQDDYNGWDI
Mb0134c|M.bovis_AF2122/97 SRPGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDI
Rv0129c|M.tuberculosis_H37Rv SRPGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDI
MMAR_0328|M.marinum_M SRPGLPVEYLQIPSAAMGRDIKVQFQGGGAHSVYLLDGLRAQDDYNGWDI
MUL_4793|M.ulcerans_Agy99 SRPGLPVEYLQIPSAAMGRDIKVQFQGGGAHSVYLLDGLRAQDDYNGWDI
MAB_0176|M.abscessus_ATCC_1997 SRPGLPVEYLQVPSASMGREIKVQFQPGGAKAVYLLDGLRARDDFSGWDI
Mflv_5146|M.gilvum_PYR-GCK SRPGLPIEQLDVPSPSMGRTIRVEFQGGGPHSVLLLDGLRAQDDFNGWDI
Mvan_1190|M.vanbaalenii_PYR-1 SRDGLPIEQLDVPSPSMGRHIRVEFQGGGPHSVLLLDGLRAQDDYNGWDI
TH_1495|M.thermoresistible__bu SRDGLPVERLAVPSPSMGRDIIVQFQGGGPHSVYLLDGLRAQEDANGWDI
MSMEG_6583|M.smegmatis_MC2_155 SRDGLPVERLQVPSAAMGRDITVQFQGGGPHALYLLDGLRAQDDANGWDI
*: ***:* * :**.:**: * ::** ** ::: *******::* .****
MLBr_02655|M.leprae_Br4923 NTPAFEEYYHSGLSVIMPVGGQSSFYSNWYQPSQGNGQHYTYKWETFLTQ
MAV_5183|M.avium_104 NTPAFEEFYQSGLSVIMPVGGQSSFYSNWYQPSSGNGQNYTYKWETFLTQ
Mb0134c|M.bovis_AF2122/97 NTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTR
Rv0129c|M.tuberculosis_H37Rv NTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTR
MMAR_0328|M.marinum_M NTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTR
MUL_4793|M.ulcerans_Agy99 NTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTR
MAB_0176|M.abscessus_ATCC_1997 ETTAFEDYYQSGISMVMPVGGQSSFYTDWYNPAKGKDGVWTYKWETFTTQ
Mflv_5146|M.gilvum_PYR-GCK NTSAFEWFYESGVSVIMPVGGQSSFYADWYRPARNNNATLTYKWETFLTN
Mvan_1190|M.vanbaalenii_PYR-1 NTAAFEWFHESGVSVIMPVGGVASFYADWYRPAKNRNGTLTYKWETFLTR
TH_1495|M.thermoresistible__bu NTAAFEWFHDSGISVVMPVGGESSFYTDWYQPARSRSGTVTYKWETFLTK
MSMEG_6583|M.smegmatis_MC2_155 NTAAFEWFYQSGISVVMPVGGQSSFYTDWYRPAVGSAGTTTYKWETFLTR
:*.*** ::.**:*::***** :***::**.*: . ******* *.
MLBr_02655|M.leprae_Br4923 EMPSWLQANKNVLPTGNAAVGLSMSGSSALILASYYPQQFPYAASLSGFL
MAV_5183|M.avium_104 EMPLWMQSNKQVSPAGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFL
Mb0134c|M.bovis_AF2122/97 EMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFL
Rv0129c|M.tuberculosis_H37Rv EMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFL
MMAR_0328|M.marinum_M EMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFL
MUL_4793|M.ulcerans_Agy99 EMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFL
MAB_0176|M.abscessus_ATCC_1997 ELPAYLAANKGISQTGNAVVGLSMGASAALTLSIYHPQLFVYAGALSGFL
Mflv_5146|M.gilvum_PYR-GCK ELPTWLATHRGQDPFGNAVVGLSMSGSAALTLAAWYPRQYKFAASLSGYL
Mvan_1190|M.vanbaalenii_PYR-1 ELPAWLAANRGQDPFGNAVVGLSMSGSAALTLAAWYPRQYKFAASLSGYL
TH_1495|M.thermoresistible__bu ELPAWLAENRGQDPNGNAVVGLSMSGGAALNLATWYPQQFIFASSLSGYL
MSMEG_6583|M.smegmatis_MC2_155 ELPAWLAANRGVEPTGNAVVGLSMSGGAALNLATWYPQQFIFAGALSGFL
*:* :: :: ***.*****...:** *: ::*: : :*.:***:*
MLBr_02655|M.leprae_Br4923 NPSEGWWPTMIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVAN
MAV_5183|M.avium_104 NPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVAN
Mb0134c|M.bovis_AF2122/97 NPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVAN
Rv0129c|M.tuberculosis_H37Rv NPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVAN
MMAR_0328|M.marinum_M NPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVAN
MUL_4793|M.ulcerans_Agy99 NPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVAN
MAB_0176|M.abscessus_ATCC_1997 NPSD--MKFQIGLAMGDAGGFSASDMWGPDSDPAWQRNDPFLNIQKIIDN
Mflv_5146|M.gilvum_PYR-GCK APSQKFWPSLIDIAMQDAGGFDSFDMWGKPGSPAWLRADPMLNINRLVAN
Mvan_1190|M.vanbaalenii_PYR-1 APSRGLWPALIDIAMQDAGGFDSYDMWGKPGSPAWLRADPTVNVNRLVAN
TH_1495|M.thermoresistible__bu SPSQGLWPTLIGVAMQDAGGYNARDMWGPTSDIAWRRNDPTVNVARLAAN
MSMEG_6583|M.smegmatis_MC2_155 NPSQGLWPTMIGFAMKDAGGYNSADMWGLANDPAWRRNDPMVNINRLVAN
** *..** *:**:.: .*** . ** * ** ::: :: *
MLBr_02655|M.leprae_Br4923 NTRIWVYCGNGAPNELGG-----DNIPAKFLESLTLSTNEIFQNTYAASG
MAV_5183|M.avium_104 NTRIWVYCGNGTPSDLGG-----DNVPAKFLEGLTLRTNEQFQNNYAAAG
Mb0134c|M.bovis_AF2122/97 NTRIWVYCGNGTPSDLGG-----DNIPAKFLEGLTLRTNQTFRDTYAADG
Rv0129c|M.tuberculosis_H37Rv NTRIWVYCGNGTPSDLGG-----DNIPAKFLEGLTLRTNQTFRDTYAADG
MMAR_0328|M.marinum_M NTRIWVYCGNGTPSDLGG-----DNMPAKFLEGLTLRTNQTFRDTYLASG
MUL_4793|M.ulcerans_Agy99 NTRIWVYCGNGTPSDLGG-----DNMPAKFLEGLTLRTNQTFRDTYLASG
MAB_0176|M.abscessus_ATCC_1997 GTRLWIYCGTGDSTDLDATRNGFENFTGGFLEGMAIGSNKKFVEAYTAAG
Mflv_5146|M.gilvum_PYR-GCK RTALWVYCGNGVASDLDTGTDLGVNISAGSLETITIATNKEFRDKYLAAG
Mvan_1190|M.vanbaalenii_PYR-1 RTALWIYCGNGVTSDLDTGSDFGRNFSAGYLETITVSTNKEFQQKYLAAG
TH_1495|M.thermoresistible__bu NTALWIYCGSGAMSDLDSGTDFGNNFSAQYLENITLSSNKEFQQKYVAAG
MSMEG_6583|M.smegmatis_MC2_155 NTAIWVYCGNGAPSDLDAAGDFGQLYSAQFLENITVNTNKEFQKRYLAAG
* :*:***.* .:*. .. ** ::: :*: * . * * *
MLBr_02655|M.leprae_Br4923 GRNGVFNFPPNGTHSWPYWNQQLVAMKPDIQQILNGSNNNA---------
MAV_5183|M.avium_104 GRNGVFNFPANGTHSWPYWNQQLMAMKPDMQQVLLSGNTTAAPAQPAQPA
Mb0134c|M.bovis_AF2122/97 GRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAPAA--
Rv0129c|M.tuberculosis_H37Rv GRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAPAA--
MMAR_0328|M.marinum_M GRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEAPA
MUL_4793|M.ulcerans_Agy99 GRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEAPA
MAB_0176|M.abscessus_ATCC_1997 GKNAHIEFPPGGIHNWTYWGQQLRAMKPDMVAYLQSH-------------
Mflv_5146|M.gilvum_PYR-GCK GRNAIFNFPPNGTHSWGYWGAQLQAMKPDIVRLLNPPPPPPPAP--LPPG
Mvan_1190|M.vanbaalenii_PYR-1 GRNAVFNFPPNGTHSWGYWGAQLQAMKADIVRLLAPPPPPPPPPGLPPPG
TH_1495|M.thermoresistible__bu GRNAIFNFPANGTHSWAYWGSQLQEMKPQLLRVLGVTTAAPQTP------
MSMEG_6583|M.smegmatis_MC2_155 GHNAVFNFPPNGTHAWGYWGAQLQAMKPDLLRVLGVGAPAPAAPAAPAPA
*:*. ::**..* * * **. ** ** :: *
MLBr_02655|M.leprae_Br4923 --------------------------------------------------
MAV_5183|M.avium_104 QPAQPAQP--------AQPAT-----------------------------
Mb0134c|M.bovis_AF2122/97 --------------------------------------------------
Rv0129c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0328|M.marinum_M APVAPAA-------------------------------------------
MUL_4793|M.ulcerans_Agy99 APVAPAA-------------------------------------------
MAB_0176|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_5146|M.gilvum_PYR-GCK APLPPPP-------APPAPPAPR---------------------------
Mvan_1190|M.vanbaalenii_PYR-1 APVPPPP-------AMPVPAPAG---------------------------
TH_1495|M.thermoresistible__bu APAAPPI-------AGAHPAGHP---------------------------
MSMEG_6583|M.smegmatis_MC2_155 APVPAAPGMPVAPVAPAVPGAQGLPAAPAYPVAPGVQGVPGVQGVPAAPA
MLBr_02655|M.leprae_Br4923 ------------
MAV_5183|M.avium_104 ------------
Mb0134c|M.bovis_AF2122/97 ------------
Rv0129c|M.tuberculosis_H37Rv ------------
MMAR_0328|M.marinum_M ------------
MUL_4793|M.ulcerans_Agy99 ------------
MAB_0176|M.abscessus_ATCC_1997 ------------
Mflv_5146|M.gilvum_PYR-GCK ------------
Mvan_1190|M.vanbaalenii_PYR-1 ------------
TH_1495|M.thermoresistible__bu ------------
MSMEG_6583|M.smegmatis_MC2_155 SPAVALPATRPV