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M. thermoresistible (build 8) TH_1961 (fbpA)

annotation: SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) (FIBRONECTIN-BINDING PROTEIN A) (ANTIGEN 85 COMPLEX A)
coordinates: 3808046 - 3809071
length: 342

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1961fbpA-100% (342)SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) (FIBRONECTIN-BINDING PROTEIN A) (ANTIGEN 85 COMPLEX A)
M. thermoresistible (build 8)TH_2078fbpAe-10858.41% (339) SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A)
M. thermoresistible (build 8)TH_1495fbpAe-10659.55% (314) SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0134cfbpC1e-10961.83% (317) secreted antigen 85-C FBPC (85C) (antigen 85 complex C)
M. gilvum PYR-GCKMflv_3241-1e-12369.01% (313) putative esterase
M. tuberculosis H37RvRv0129cfbpC1e-10961.83% (317) secreted antigen 85-C FBPC (85C) (antigen 85 complex C)
M. leprae Br4923MLBr_02655fbpC21e-10760.33% (305) secreted antigen 85A, mycolyltransferase
M. abscessus ATCC 19977MAB_0176-1e-9454.21% (321) antigen 85-A precursor
M. marinum MMMAR_0328fbpC1e-10760.58% (312) secreted antigen 85-C FbpC
M. avium 104MAV_5183-1e-11058.65% (341) antigen 85-C
M. smegmatis MC2 155MSMEG_2078-1e-11362.81% (320) antigen 85-C
M. ulcerans Agy99MUL_4793fbpC1e-10760.58% (312) secreted antigen 85-C FbpC
M. vanbaalenii PYR-1Mvan_2954-1e-12368.87% (318) putative esterase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3241|M.gilvum_PYR-GCK          MNLMRIVVRRLGTAAVT---------------ALLVCGLITVTGG----A
Mvan_2954|M.vanbaalenii_PYR-1       MEPIRDLIRRMAVGAVT---------------ALLLSGLIAVAGAS---A
TH_1961|M.thermoresistible__bu      MNQVKMSGQEKAMNFSAKPRRNGSYRHWFRRLGAVIAALVLLPALT---A
MLBr_02655|M.leprae_Br4923          MKFLQQMRKLFGLAAKFPARLTIAVIG-----TALLAGLVGVVGDT---A
MAV_5183|M.avium_104                MSFIEKVRKLRGAAATMPRRLAIAAVG-----ASLLSGVAVAAGGS---P
Mb0134c|M.bovis_AF2122/97           MTFFEQVRRLRSAATTLPRRLAIAAMG-----AVLVYGLVGTFGGP---A
Rv0129c|M.tuberculosis_H37Rv        MTFFEQVRRLRSAATTLPRRLAIAAMG-----AVLVYGLVGTFGGP---A
MMAR_0328|M.marinum_M               MKFVEKLR---GAAAGAPRRLTIAAIG-----AALLSGLVGAVGGA---A
MUL_4793|M.ulcerans_Agy99           MKFVEKLR---GAAAGAPRRLTIAAIG-----AALLSGLVGAVGGA---A
MSMEG_2078|M.smegmatis_MC2_155      MTFIDKIR------GHWARRMTVAAVA-----ALLLPGLVGVVGGS---A
MAB_0176|M.abscessus_ATCC_1997      MKLFSKMRG--ALARQSARRIAVAATA-----VAVLPGVAGIVGGTALTP
                                    *  .                              :: .:    .     .

Mflv_3241|M.gilvum_PYR-GCK          TAGAYSRPGLPVETLMVPSAAMGRDIPVKFQGGGP--RAVYLLDGLRARD
Mvan_2954|M.vanbaalenii_PYR-1       PAGAYSRPGLPVETLMVPSAAMGRDIPVKFQGGGP--RAVYLLDGMRARD
TH_1961|M.thermoresistible__bu      VVGAMPRAQAAPETLMVPSPSMGRDIPVQFQGGGE--KAVYLLDGMRARD
MLBr_02655|M.leprae_Br4923          IAVAFSKPGLPVEYLQVPSPSMGHDIKIQFQGGGQ--HAVYLLDGLRAQE
MAV_5183|M.avium_104                VAGAFSKPGLPVEYLEVPSPSMGRNIKVQFQGGGP--HAVYLLDGLRAQD
Mb0134c|M.bovis_AF2122/97           TAGAFSRPGLPVEYLQVPSASMGRDIKVQFQGGGP--HAVYLLDGLRAQD
Rv0129c|M.tuberculosis_H37Rv        TAGAFSRPGLPVEYLQVPSASMGRDIKVQFQGGGP--HAVYLLDGLRAQD
MMAR_0328|M.marinum_M               TAGAFSRPGLPVEYLQIPSAAMGRDIKVQFQGGGA--HSVYLLDGLRAQD
MUL_4793|M.ulcerans_Agy99           TAGAFSRPGLPVEYLQIPSAAMGRDIKVQFQGGGA--HSVYLLDGLRAQD
MSMEG_2078|M.smegmatis_MC2_155      TAGAFSRPGLPVEYLMVPSPSMGRDIKVQFQSGGPGSHAVYLLDGLRAQD
MAB_0176|M.abscessus_ATCC_1997      VAGAFSRPGLPVEYLQVPSASMGREIKVQFQPGGA--KAVYLLDGLRARD
                                     . * .:.  . * * :**.:**::* ::** **   ::******:**::

Mflv_3241|M.gilvum_PYR-GCK          DNSGWDIETAAFETFFESGLSVVMPVGGMSSFYTNWQGPAVGNGGTHNYQ
Mvan_2954|M.vanbaalenii_PYR-1       DNSGWDIETNAFETFFESGLSVVMPVGGMSSFYTNWRGPATGNGTTYNYQ
TH_1961|M.thermoresistible__bu      DRNGWDIETGAFSWFEGSGLSVVAPVGGMSSFYTDWYGPAVGNGRTQTYK
MLBr_02655|M.leprae_Br4923          DYNGWDINTPAFEEYYHSGLSVIMPVGGQSSFYSNWYQPSQGNGQHYTYK
MAV_5183|M.avium_104                DYNGWDINTPAFEEFYQSGLSVIMPVGGQSSFYSNWYQPSSGNGQNYTYK
Mb0134c|M.bovis_AF2122/97           DYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYK
Rv0129c|M.tuberculosis_H37Rv        DYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYK
MMAR_0328|M.marinum_M               DYNGWDINTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYK
MUL_4793|M.ulcerans_Agy99           DYNGWDINTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYK
MSMEG_2078|M.smegmatis_MC2_155      DFNGWDINTNAFEMFLDSGLSVVMPVGGQSSFYSDWYQPACGNNGCVTYK
MAB_0176|M.abscessus_ATCC_1997      DFSGWDIETTAFEDYYQSGISMVMPVGGQSSFYTDWYNPAKGKDGVWTYK
                                    * .****:* **. :  **:*:: **** ****::*  *: .:.   .*:

Mflv_3241|M.gilvum_PYR-GCK          WETFLTSELPAYLAANKGISPSGNAVVGLSMSGSAALIMAAYHPGQFSYA
Mvan_2954|M.vanbaalenii_PYR-1       WETFLTSELPAYLAANKGISPSGNAVVGLSMSGSAALILAAYHPGQFSYA
TH_1961|M.thermoresistible__bu      WETFLTSELPAWLAENRGVSPSGNAVVGVSMSGSSALILAAYHPGQFSYA
MLBr_02655|M.leprae_Br4923          WETFLTQEMPSWLQANKNVLPTGNAAVGLSMSGSSALILASYYPQQFPYA
MAV_5183|M.avium_104                WETFLTQEMPLWMQSNKQVSPAGNAAVGLSMSGGSALILAAYYPQQFPYA
Mb0134c|M.bovis_AF2122/97           WETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYA
Rv0129c|M.tuberculosis_H37Rv        WETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYA
MMAR_0328|M.marinum_M               WETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYA
MUL_4793|M.ulcerans_Agy99           WETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYA
MSMEG_2078|M.smegmatis_MC2_155      WETFLTSELPEWLAANRDVAATGNAAIGLSMAGSAALILAAYHPDRFIYA
MAB_0176|M.abscessus_ATCC_1997      WETFTTQELPAYLAANKGISQTGNAVVGLSMGASAALTLSIYHPQLFVYA
                                    **** * *:* ::  *: :  :***.:*:**...:** :: *:*  * **

Mflv_3241|M.gilvum_PYR-GCK          GSLSGYLNLSEGVWPLLVGIAMRDAGGFSATSMWGLGGSA--AWKRNDPT
Mvan_2954|M.vanbaalenii_PYR-1       GSLSGYLNLSDGVWPLLVSIAMRDAGGFSSTAMWGLGGGP--AWQRNDPT
TH_1961|M.thermoresistible__bu      GSLSGYLNLSEDYWPLLIAVAMADAGGFNALDMWGPYGGP--AWQRNDPM
MLBr_02655|M.leprae_Br4923          ASLSGFLNPSEGWWPTMIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPM
MAV_5183|M.avium_104                ASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPM
Mb0134c|M.bovis_AF2122/97           ASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDP--AWKRNDPM
Rv0129c|M.tuberculosis_H37Rv        ASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDP--AWKRNDPM
MMAR_0328|M.marinum_M               ASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPM
MUL_4793|M.ulcerans_Agy99           ASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPM
MSMEG_2078|M.smegmatis_MC2_155      GSMSGFLNPSEGWWPFLINISMGDAGGYKANDMWGPTEDPNSAWKRNDPM
MAB_0176|M.abscessus_ATCC_1997      GALSGFLNPSD--MKFQIGLAMGDAGGFSASDMWGPDSDP--AWQRNDPF
                                    .::**:** *:      : ::* *:**:.:  ***   ..  **:**** 

Mflv_3241|M.gilvum_PYR-GCK          VNVGKLVANGTRIWVYCGTGRPGELGGGG----DVPGQLLEAITLDSNRE
Mvan_2954|M.vanbaalenii_PYR-1       VNVGRLVANGTRIWVYCGTGRPGELGGGG----DVPGQVLEAITLDSNRE
TH_1961|M.thermoresistible__bu      LQVGRLVANGTRIWVYTGNGNPTELDAGLG-DAQIPAQFLEGLTVRTSRE
MLBr_02655|M.leprae_Br4923          VQIPRLVANNTRIWVYCGNGAPNELGGDN-----IPAKFLESLTLSTNEI
MAV_5183|M.avium_104                VQIPRLVANNTRIWVYCGNGTPSDLGGDN-----VPAKFLEGLTLRTNEQ
Mb0134c|M.bovis_AF2122/97           VQIPRLVANNTRIWVYCGNGTPSDLGGDN-----IPAKFLEGLTLRTNQT
Rv0129c|M.tuberculosis_H37Rv        VQIPRLVANNTRIWVYCGNGTPSDLGGDN-----IPAKFLEGLTLRTNQT
MMAR_0328|M.marinum_M               VQIPRLVANNTRIWVYCGNGTPSDLGGDN-----MPAKFLEGLTLRTNQT
MUL_4793|M.ulcerans_Agy99           VQIPRLVANNTRIWVYCGNGTPSDLGGDN-----MPAKFLEGLTLRTNQT
MSMEG_2078|M.smegmatis_MC2_155      VQIPRLVANNTRIWVYCGNGQPNELGGGD-----LPATFLEGLTIRTNET
MAB_0176|M.abscessus_ATCC_1997      LNIQKIIDNGTRLWIYCGTGDSTDLDATRNGFENFTGGFLEGMAIGSNKK
                                    ::: ::: *.**:*:* *.* . :*..       ... .**.::: :.. 

Mflv_3241|M.gilvum_PYR-GCK          FQRQYQSAGGSNGVFNFPPNGTHGWGYWGSQLNAMKPDIQRVLGA-----
Mvan_2954|M.vanbaalenii_PYR-1       FQRRYQAAGGGNGVFNFPPDGTHGWGYWGAQLGAMKPDIQRVLGA-----
TH_1961|M.thermoresistible__bu      FQRAYQRAGGTNAVFNFPASGTHSWGYWGGQLQAMIPDIQRTLGAAPAE-
MLBr_02655|M.leprae_Br4923          FQNTYAASGGRNGVFNFPPNGTHSWPYWNQQLVAMKPDIQQILNGSNNNA
MAV_5183|M.avium_104                FQNNYAAAGGRNGVFNFPANGTHSWPYWNQQLMAMKPDMQQVLLSGNTTA
Mb0134c|M.bovis_AF2122/97           FRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPA
Rv0129c|M.tuberculosis_H37Rv        FRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPA
MMAR_0328|M.marinum_M               FRDTYLASGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPA
MUL_4793|M.ulcerans_Agy99           FRDTYLASGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPA
MSMEG_2078|M.smegmatis_MC2_155      FRDNYIAAGGNNGVFNFPNNGTHNWAYWGRELQAMVPDLQRVLG------
MAB_0176|M.abscessus_ATCC_1997      FVEAYTAAGGKNAHIEFPPGGIHNWTYWGQQLRAMKPDMVAYLQSH----
                                    *   *   ** *. ::** .* *.* **. :* **  *:   *       

Mflv_3241|M.gilvum_PYR-GCK          ----------------------
Mvan_2954|M.vanbaalenii_PYR-1       ----------------------
TH_1961|M.thermoresistible__bu      ----------------------
MLBr_02655|M.leprae_Br4923          ----------------------
MAV_5183|M.avium_104                APAQPAQPAQPAQPAQPAQPAT
Mb0134c|M.bovis_AF2122/97           APAAPAA---------------
Rv0129c|M.tuberculosis_H37Rv        APAAPAA---------------
MMAR_0328|M.marinum_M               APAAPEAPAAPVAPAA------
MUL_4793|M.ulcerans_Agy99           APAAPEAPAAPVAPAA------
MSMEG_2078|M.smegmatis_MC2_155      ----------------------
MAB_0176|M.abscessus_ATCC_1997      ----------------------