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TDLRIAVLGVGVMGADHVARITSRISGARVAVVNDHLVEKAEQLAASIPGCSAVADPLDAIADADVDAVV LATPGGTHEEQLLACLDQRKPVMCEKPLTTDVSTSLEIARREADLGRPLIQVGFMRRFDDEYVRLKALLD GGELGNPLMMHCVHRNPGVPAYFDSSLIVKDSLVHEVDITRYLFGEEIASVQIIKPTSNPGAPNGVVDPQ IAILRTVSGRHVDVELFVTTGVAYEVRTEVVGEHGSAIIGLDVGLIRKKGPGSWGGTLTPGFRERFGPAY DTEIQRWVDAVHSGTNVCGPTAWDGYAAAAVCAAGVESLETGLPVDVQLADEVTSPSPQGVRESDGCR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2598 | - | - | 100% (349) | inositol 2-dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2613 | - | 5e-28 | 29.13% (333) | inositol 2-dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0624 | - | 2e-07 | 27.78% (198) | oxidoreductase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2306c | - | 1e-08 | 26.73% (202) | putative oxidoreductase |
| M. marinum M | MMAR_2628 | - | 9e-10 | 32.64% (144) | hypothetical protein MMAR_2628 |
| M. avium 104 | MAV_2643 | - | 1e-10 | 24.24% (363) | oxidoreductase family protein, NAD-binding Rossmann fold |
| M. smegmatis MC2 155 | MSMEG_4666 | - | 1e-136 | 68.33% (341) | myo-inositol 2-dehydrogenase |
| M. thermoresistible (build 8) | TH_3104 | - | 6e-08 | 23.33% (270) | PUTATIVE oxidoreductase domain protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4020 | - | 1e-165 | 84.64% (332) | inositol 2-dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2598|M.gilvum_PYR-GCK ----MTDLRIAVLGVGVMGADHVARITSRISGARVAVVNDHLVEKAEQLA
Mvan_4020|M.vanbaalenii_PYR-1 ----MSELRVAVLGVGVMGADHVARITSRISGARVSVVNDYVTEKAEQIA
MSMEG_4666|M.smegmatis_MC2_155 ----MSDLRVAVLGVGVMGADHVERLSTRIAGVKVAVVNDFIETRAEEIA
MAV_2643|M.avium_104 -----MTLRVGIIGVGWGARVQVPGFR-AAKGFEPVALCARTPDRLERAA
TH_3104|M.thermoresistible__bu -------MRVLVIGTGFGRQAMAPVYR--GLGFDVEVVSPRDESALHRAL
MAB_2306c|M.abscessus_ATCC_199 ---MPESIRWGIVGPGRIAGNVARDFP-LTPRAELAAVASRSLPRAQDFA
MMAR_2628|M.marinum_M MTGHGSPLRIGILGAARIAPQALVKPAQGNVEAVVAAVAARDGARAQAFA
:* ::* . .: .
Mflv_2598|M.gilvum_PYR-GCK ASIPGCSAVADPLDAIADADVDAVVLATPGGTHEEQLLACLDQRKPVMCE
Mvan_4020|M.vanbaalenii_PYR-1 SEVDGCRAVVDPLDAIADPEVDAVVLATPGSTHEKQLLACLDHRKPVMCE
MSMEG_4666|M.smegmatis_MC2_155 AGVPGCRVVSDPLEAIADPDVDAVVLATPGPTHDKQLLACLEQRKPVLCE
MAV_2643|M.avium_104 AKLGIEQTSTDWQSFVTRDDLDVISVATPTVLHHEMTIAALAAGKPVLCE
TH_3104|M.thermoresistible__bu N-----------------AGVDLVSVHSPPFLHRQHVTAAVDRGYPVLCD
MAB_2306c|M.abscessus_ATCC_199 GAHQIPRAYGSYRELLADPDIDAVYIATPHPQHRQTAIAALTAGKAILVE
MMAR_2628|M.marinum_M AKHGISRVHSSYEALIADPTLDAVYIPLPNGLHGRWTQAALTAGKHVLCE
:* : : * * . *.: :: :
Mflv_2598|M.gilvum_PYR-GCK KPLTTDVSTSLEIARREADLGRPLIQVGFMRRFDDEYVRLKALLDGGELG
Mvan_4020|M.vanbaalenii_PYR-1 KPLTTDVFTSLEIARREAELECPLIQVGFMRRFDDEYMRLKALLDGGELG
MSMEG_4666|M.smegmatis_MC2_155 KPLTTDVDSALDVVRREAELGVRLIQVGFMRRFDPEYAELKTLIDAGEFG
MAV_2643|M.avium_104 KPLAGDLEAARHMVRAATDSKLPTACC-FENRWNPDWLAVADKVRSGFLG
TH_3104|M.thermoresistible__bu KPFGRNADEARAMRDHAARRAVPTFLN-FELRHQPARAEFKKLADSGVIG
MAB_2306c|M.abscessus_ATCC_199 KTFTATVSGAQEVIDIARARGVFAMEA-MWTRFQPAIVAAKDLVDDGAIG
MMAR_2628|M.marinum_M KPFTANAAEADEIAQLAATTDRVVMEA-FHYRYHPLTLRIEQILASGELG
*.: : : : * . * :*
Mflv_2598|M.gilvum_PYR-GCK -----------------NPLMMHCVHRNPGVPAYFDSSLIVKDSLVHEVD
Mvan_4020|M.vanbaalenii_PYR-1 -----------------QPLVMHCVHRNPGVPSYFDSSLIVKDSLVHEVD
MSMEG_4666|M.smegmatis_MC2_155 -----------------QPLVLHCVHRNAAVPPSFDSTMIVKDSLVHEVD
MAV_2643|M.avium_104 SQYLARVSRSASYWHPSHPLQAHWMYDREQGGGYLAGMLVHDLDFLTSLL
TH_3104|M.thermoresistible__bu ---TPRHLSWTFFGAGLRGRPHGWINERDTGGGWIGANGAHLIDYTRYLF
MAB_2306c|M.abscessus_ATCC_199 -----------------EVRQVQADLGVDRPFDREDRLFNPALGGGALLD
MMAR_2628|M.marinum_M ------------------TLQRVETSMCFPLPKFSDIRYNYALAGGATMD
:
Mflv_2598|M.gilvum_PYR-GCK ITRYLFGEEIA--SVQIIKPTSNPG-APNGVVDPQIAILRTVSGRHVDVE
Mvan_4020|M.vanbaalenii_PYR-1 VTRYLFGEEIA--SVQIVRPVSNPA-APEGVIDPQIAILRTVSGRHVDVE
MSMEG_4666|M.smegmatis_MC2_155 VTRFLFDEEIA--SVHILRPTPNPG-APEGIQDPQIAIMKTPSGKHVDVE
MAV_2643|M.avium_104 GRPVSVCAEVR--TSDPVRELPDGGTLPVTADDTAALLMRMESGVTVILS
TH_3104|M.thermoresistible__bu GSEITGCGGVAR-IEDPHRPDPQGRPRRATAEDAYSAWFVTENGCTATHD
MAB_2306c|M.abscessus_ATCC_199 LGVYVVSLAQYF-LGDPAAVVAHGSLFPTGVDAEAGLLLRYDDGRTATLL
MMAR_2628|M.marinum_M AGCYAVHMARTFGGGTPEVVSAQAKRRDSEVDRAMTAELRFPAGHSGRIQ
.. : *
Mflv_2598|M.gilvum_PYR-GCK LFVTTGVAYEVRTEVVGEHGSAIIGLDVGLIRKKGPGSWGGTLTPGFRER
Mvan_4020|M.vanbaalenii_PYR-1 LFVTTGVAYEVRTEVVGERGSAMIGLDVGLIRKSAPGTWGGLIAPGFRER
MSMEG_4666|M.smegmatis_MC2_155 LFVTTGVGYEVRTELVAEKGTAMIGLDVGLIRKGVPGTWGGAIAPDFRVR
MAV_2643|M.avium_104 LSVMGAHADHYRLELFGSDGTIIGDGDLRSAAYSLGAATDAGLSPLTVDE
TH_3104|M.thermoresistible__bu TAFAAAVALPPRMVLTGSAGALELIGDSRLIVHRADADPMTHEFPPAPPR
MAB_2306c|M.abscessus_ATCC_199 CSLLHHTPGQAR--IFGTEGWIDILPRFHHPREIVLHRKGAAPEPMVRPP
MMAR_2628|M.marinum_M CSMWSSHLLNMSARVVGDRGELRVLNPVVPQLFHRLTVQSAIGRRVERFP
. : . *
Mflv_2598|M.gilvum_PYR-GCK FGPAYDTEIQRWVDAVHSGTN------VCGPTAWDGYAAAAVCAAGVESL
Mvan_4020|M.vanbaalenii_PYR-1 FGRAYDTEIQRWVDAVRAGTN------IDGPTAWDGYAAAAVCAAGVESL
MSMEG_4666|M.smegmatis_MC2_155 FGTAYDIEFQRWVAAVRHGIATGSDDYTDGPTAWDGYAAAAVCAAGVESL
MAV_2643|M.avium_104 REPAHPERLPGGLAGHASRAM--------ALMLQDWLPAFDGGPSGAATF
TH_3104|M.thermoresistible__bu --SFYEPALTPWLEQVADALR--------------------TGRPATPSF
MAB_2306c|M.abscessus_ATCC_199 VGGGYSHELAEVTECLLNGRA----------------------QSSVMPL
MMAR_2628|M.marinum_M RRASYAYQLDAFTGAILRGEA------------------------VKTTP
: : .
Mflv_2598|M.gilvum_PYR-GCK ETGLPVDVQLADEVTSPSPQGVRESDGCR
Mvan_4020|M.vanbaalenii_PYR-1 ESGLPVPVHLAER---PDRSTIRPR----
MSMEG_4666|M.smegmatis_MC2_155 AGGQPVEVKMVER------ASINGA----
MAV_2643|M.avium_104 EDGLLSLAVIDAAHRSAEGGGWEQVQV--
TH_3104|M.thermoresistible__bu DDGVAVAEVMDRLR----ANVIEQVMQ--
MAB_2306c|M.abscessus_ATCC_199 ADTLAVQRVLNTACEQLGVDHTEDPADLD
MMAR_2628|M.marinum_M QDAVQNMTVIDAIYRAAGLPLRNPS----
: .