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MSELRVAVLGVGVMGADHVARITSRISGARVSVVNDYVTEKAEQIASEVDGCRAVVDPLDAIADPEVDAV VLATPGSTHEKQLLACLDHRKPVMCEKPLTTDVFTSLEIARREAELECPLIQVGFMRRFDDEYMRLKALL DGGELGQPLVMHCVHRNPGVPSYFDSSLIVKDSLVHEVDVTRYLFGEEIASVQIVRPVSNPAAPEGVIDP QIAILRTVSGRHVDVELFVTTGVAYEVRTEVVGERGSAMIGLDVGLIRKSAPGTWGGLIAPGFRERFGRA YDTEIQRWVDAVRAGTNIDGPTAWDGYAAAAVCAAGVESLESGLPVPVHLAERPDRSTIRPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4020 | - | - | 100% (342) | inositol 2-dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0387 | - | e-149 | 76.85% (337) | inositol 2-dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_3968 | - | 3e-25 | 28.49% (337) | inositol 2-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2598 | - | 1e-165 | 84.64% (332) | inositol 2-dehydrogenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2612 | - | 1e-08 | 31.47% (143) | putative oxidoreductase |
| M. marinum M | MMAR_2628 | - | 2e-08 | 29.45% (146) | hypothetical protein MMAR_2628 |
| M. avium 104 | MAV_2643 | - | 2e-09 | 22.93% (362) | oxidoreductase family protein, NAD-binding Rossmann fold |
| M. smegmatis MC2 155 | MSMEG_4666 | - | 1e-140 | 72.27% (339) | myo-inositol 2-dehydrogenase |
| M. thermoresistible (build 8) | TH_3104 | - | 1e-07 | 25.18% (282) | PUTATIVE oxidoreductase domain protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4020|M.vanbaalenii_PYR-1 ----MSELRVAVLGVGVMGADHVARITSRISGARVSVVNDYVTEKAEQIA
Mflv_2598|M.gilvum_PYR-GCK ----MTDLRIAVLGVGVMGADHVARITSRISGARVAVVNDHLVEKAEQLA
MSMEG_4666|M.smegmatis_MC2_155 ----MSDLRVAVLGVGVMGADHVERLSTRIAGVKVAVVNDFIETRAEEIA
MAV_2643|M.avium_104 -----MTLRVGIIGVGWGARVQVPGFR-AAKGFEPVALCARTPDRLERAA
TH_3104|M.thermoresistible__bu -------MRVLVIGTGFGRQAMAPVYR--GLGFDVEVVSPRDESALHRAL
MAB_2612|M.abscessus_ATCC_1997 ------MLKVGIIGAGGVARAHARALN-TLKSAELVGVLDIDARAAESFT
MMAR_2628|M.marinum_M MTGHGSPLRIGILGAARIAPQALVKPAQGNVEAVVAAVAARDGARAQAFA
::: ::*.. : .
Mvan_4020|M.vanbaalenii_PYR-1 SEVDGCRAVVDPLDAIADPEVDAVVLATPGSTHEKQLLACLDHRKPVMCE
Mflv_2598|M.gilvum_PYR-GCK ASIPGCSAVADPLDAIADADVDAVVLATPGGTHEEQLLACLDQRKPVMCE
MSMEG_4666|M.smegmatis_MC2_155 AGVPGCRVVSDPLEAIADPDVDAVVLATPGPTHDKQLLACLEQRKPVLCE
MAV_2643|M.avium_104 AKLGIEQTSTDWQSFVTRDDLDVISVATPTVLHHEMTIAALAAGKPVLCE
TH_3104|M.thermoresistible__bu N-----------------AGVDLVSVHSPPFLHRQHVTAAVDRGYPVLCD
MAB_2612|M.abscessus_ATCC_1997 DAYGG---TPVTDVDALLELADAVVVASPNFTHRDHSLSALRAGRSVLCE
MMAR_2628|M.marinum_M AKHGISRVHSSYEALIADPTLDAVYIPLPNGLHGRWTQAALTAGKHVLCE
* : : * * :.: *:*:
Mvan_4020|M.vanbaalenii_PYR-1 KPLTTDVFTSLEIARREAELECPLIQVGFMRRFDDEYMRLKALLDGGELG
Mflv_2598|M.gilvum_PYR-GCK KPLTTDVSTSLEIARREADLGRPLIQVGFMRRFDDEYVRLKALLDGGELG
MSMEG_4666|M.smegmatis_MC2_155 KPLTTDVDSALDVVRREAELGVRLIQVGFMRRFDPEYAELKTLIDAGEFG
MAV_2643|M.avium_104 KPLAGDLEAARHMVRAATDSKLPTACC-FENRWNPDWLAVADKVRSGFLG
TH_3104|M.thermoresistible__bu KPFGRNADEARAMRDHAARRAVPTFLN-FELRHQPARAEFKKLADSGVIG
MAB_2612|M.abscessus_ATCC_1997 KPLALSRVEAKEMVAAAGEIASPALVG-FNYRHLPVVTELRRRLQHGDFG
MMAR_2628|M.marinum_M KPFTANAAEADEIAQLAATTDR-VVMEAFHYRYHPLTLRIEQILASGELG
**: . : : * * . * :*
Mvan_4020|M.vanbaalenii_PYR-1 -----------------QPLVMHCVHRNPGVPSYFDSSLIVKDSLVHEVD
Mflv_2598|M.gilvum_PYR-GCK -----------------NPLMMHCVHRNPGVPAYFDSSLIVKDSLVHEVD
MSMEG_4666|M.smegmatis_MC2_155 -----------------QPLVLHCVHRNAAVPPSFDSTMIVKDSLVHEVD
MAV_2643|M.avium_104 SQYLARVSRSASYWHPSHPLQAHWMYDREQGGGYLAGMLVHDLDFLTSLL
TH_3104|M.thermoresistible__bu ---TPRHLSWTFFGAGLRGRPHGWINERDTGGGWIGANGAHLIDYTRYLF
MAB_2612|M.abscessus_ATCC_1997 TICAVELGFRKDSAYRRKNHTWRDSGRSNGTSGALGDLGVHLLDLLTYIS
MMAR_2628|M.marinum_M ------------------------TLQRVETSMCFPLPKFSDIRYNYALA
: :
Mvan_4020|M.vanbaalenii_PYR-1 VTRYLFGEEIA-SVQIVRPVSNPA-APEGVIDPQIAILRTVSGRHVDVEL
Mflv_2598|M.gilvum_PYR-GCK ITRYLFGEEIA-SVQIIKPTSNPG-APNGVVDPQIAILRTVSGRHVDVEL
MSMEG_4666|M.smegmatis_MC2_155 VTRFLFDEEIA-SVHILRPTPNPG-APEGIQDPQIAIMKTPSGKHVDVEL
MAV_2643|M.avium_104 GRPVSVCAEVR-TSDPVRELPDGGTLPVTADDTAALLMRMESGVTVILSL
TH_3104|M.thermoresistible__bu GSEITGCGGVARIEDPHRPDPQGRPRRATAEDAYSAWFVTENGCTATHDT
MAB_2612|M.abscessus_ATCC_1997 GGRILVDECQARITTHVTNKSDEAVEVDDHAEIYGRLSTGSIFTLVASKA
MMAR_2628|M.marinum_M GGATMDAGCYA-----VHMARTFGGGTPEVVSAQAKRRDSEVDRAMTAEL
. .
Mvan_4020|M.vanbaalenii_PYR-1 FVTTGVAYEVRTEVVGERGSAMIGLDVGLIRKSAPGTWGGLIAPGFRERF
Mflv_2598|M.gilvum_PYR-GCK FVTTGVAYEVRTEVVGEHGSAIIGLDVGLIRKKGPGSWGGTLTPGFRERF
MSMEG_4666|M.smegmatis_MC2_155 FVTTGVGYEVRTELVAEKGTAMIGLDVGLIRKGVPGTWGGAIAPDFRVRF
MAV_2643|M.avium_104 SVMGAHADHYRLELFGSDGTIIGDGDLRSAAYSLGAATDAGLSPLTVDER
TH_3104|M.thermoresistible__bu AFAAAVALPPRMVLTGSAGALELIGDSRLIVHRADADPMTHEFPPAPPR-
MAB_2612|M.abscessus_ATCC_1997 APAADCGFSIRIVGTNAVFRYHTADPGRYLVSRGADTETVDLARTLLSD-
MMAR_2628|M.marinum_M RFPAGHSGRIQCSMWSS---HLLNMSARVVGDRGELRVLNPVVPQLFHR-
. :
Mvan_4020|M.vanbaalenii_PYR-1 GRAYDTEIQRWVDAVRAGTN------IDGPTAWDGYAAAAVCAAGVESLE
Mflv_2598|M.gilvum_PYR-GCK GPAYDTEIQRWVDAVHSGTN------VCGPTAWDGYAAAAVCAAGVESLE
MSMEG_4666|M.smegmatis_MC2_155 GTAYDIEFQRWVAAVRHGIATGSDDYTDGPTAWDGYAAAAVCAAGVESLA
MAV_2643|M.avium_104 EPAHPERLPGGLAGHASRAM--------ALMLQDWLPAFDGGPSGAATFE
TH_3104|M.thermoresistible__bu -SFYEPALTPWLEQVADALR--------------------TGRPATPSFD
MAB_2612|M.abscessus_ATCC_1997 ---PDNEVHGWSDSFRSEID---------HWSRLVAVGGGANRQALATFD
MMAR_2628|M.marinum_M -LTVQSAIGRRVERFPRRAS-------YAYQLDAFTGAILRGEAVKTTPQ
. :
Mvan_4020|M.vanbaalenii_PYR-1 SGLPVPVHLAER---PDRSTIRPR-----------
Mflv_2598|M.gilvum_PYR-GCK TGLPVDVQLADEVTSPSPQGVRESDGCR-------
MSMEG_4666|M.smegmatis_MC2_155 GGQPVEVKMVER------ASINGA-----------
MAV_2643|M.avium_104 DGLLSLAVIDAAHRSAEGGGWEQVQV---------
TH_3104|M.thermoresistible__bu DGVAVAEVMDRLR----ANVIEQVMQ---------
MAB_2612|M.abscessus_ATCC_1997 DGLAAQEVLESLLRGSKPQPERLPVEHTLPTPAEL
MMAR_2628|M.marinum_M DAVQNMTVIDAIYRAAGLPLRNPS-----------
. : .