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MTLRVGIIGVGWGARVQVPGFRAAKGFEPVALCARTPDRLERAAAKLGIEQTSTDWQSFVTRDDLDVISV ATPTVLHHEMTIAALAAGKPVLCEKPLAGDLEAARHMVRAATDSKLPTACCFENRWNPDWLAVADKVRSG FLGSQYLARVSRSASYWHPSHPLQAHWMYDREQGGGYLAGMLVHDLDFLTSLLGRPVSVCAEVRTSDPVR ELPDGGTLPVTADDTAALLMRMESGVTVILSLSVMGAHADHYRLELFGSDGTIIGDGDLRSAAYSLGAAT DAGLSPLTVDEREPAHPERLPGGLAGHASRAMALMLQDWLPAFDGGPSGAATFEDGLLSLAVIDAAHRSA EGGGWEQVQV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2643 | - | - | 100% (360) | oxidoreductase family protein, NAD-binding Rossmann fold protein |
| M. avium 104 | MAV_1941 | - | 0.0 | 89.69% (359) | oxidoreductase family protein, NAD-binding Rossmann fold |
| M. avium 104 | MAV_2987 | - | 7e-13 | 27.27% (253) | NAD binding oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2613 | - | 3e-15 | 23.01% (352) | inositol 2-dehydrogenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2306c | - | 3e-14 | 25.19% (262) | putative oxidoreductase |
| M. marinum M | MMAR_2628 | - | 1e-13 | 26.35% (353) | hypothetical protein MMAR_2628 |
| M. smegmatis MC2 155 | MSMEG_3300 | - | 8e-26 | 27.33% (344) | oxidoreductase, Gfo/Idh/MocA family protein |
| M. thermoresistible (build 8) | TH_3104 | - | 2e-21 | 27.33% (344) | PUTATIVE oxidoreductase domain protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3968 | - | 5e-16 | 23.10% (355) | inositol 2-dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2613|M.gilvum_PYR-GCK ------MTSLGLIGLG----RIGAFHTETLINLPEVSRLVITDERPGVVG
Mvan_3968|M.vanbaalenii_PYR-1 ------MTTLGLIGLG----RIGAFHAETLTNLPEVSGLVVTDERPEVVS
MAV_2643|M.avium_104 -----MTLRVGIIGVG----WGARVQVPGFRAAKGFEPVALCARTPDRLE
TH_3104|M.thermoresistible__bu -------MRVLVIGTG----FGRQAMAPVYR-GLGFDVEVVSPRDESALH
MSMEG_3300|M.smegmatis_MC2_155 ----MTPIGVGVIGASPNGGWAALAHVPALRALPEYDLRAVATSRPESAE
MMAR_2628|M.marinum_M MTGHGSPLRIGILGAAR---IAPQALVKPAQGNVEAVVAAVAARDGARAQ
MAB_2306c|M.abscessus_ATCC_199 ---MPESIRWGIVGPG----RIAGNVARDFPLTPRAELAAVASRSLPRAQ
::* . . .:
Mflv_2613|M.gilvum_PYR-GCK EVAAKYGATPVESVEKLLSS--GIDGVVVAAATPAHAELTLAAVERGLPT
Mvan_3968|M.vanbaalenii_PYR-1 QLATKYGATPANSVQELLAS--GVDGVIVAAATPAHAELTLAAVERGLPT
MAV_2643|M.avium_104 RAAAKLGIEQTSTDWQSFVTRDDLDVISVATPTVLHHEMTIAALAAGKPV
TH_3104|M.thermoresistible__bu RALNAG-----------------VDLVSVHSPPFLHRQHVTAAVDRGYPV
MSMEG_3300|M.smegmatis_MC2_155 RAKVAWGVDAYHDPRRLVERR-DIDLVVVAVKVPDHYGLITDALTAGKAV
MMAR_2628|M.marinum_M AFAAKHGISRVHSSYEALIADPTLDAVYIPLPNGLHGRWTQAALTAGKHV
MAB_2306c|M.abscessus_ATCC_199 DFAGAHQIPRAYGSYRELLADPDIDAVYIATPHPQHRQTAIAALTAGKAI
:* : : * *: *
Mflv_2613|M.gilvum_PYR-GCK FCEKPIASTAAESARVAEIIARSGVPVQVGYQRRFDTAFAAVKQAADSGS
Mvan_3968|M.vanbaalenii_PYR-1 FCEKPIAATAAESARVGEVITRSGVPVQVGYQRRFDAAFAAVKHAVDDGS
MAV_2643|M.avium_104 LCEKPLAGDLEAARHMVRAATDSKLPTACCFENRWNPDWLAVADKVRSGF
TH_3104|M.thermoresistible__bu LCDKPFGRNADEARAMRDHAARRAVPTFLNFELRHQPARAEFKKLADSGV
MSMEG_3300|M.smegmatis_MC2_155 FSEWPLGVALEQAQILHAEAVVAGVPTVVGLQARFAPAIRRMRELVDAGY
MMAR_2628|M.marinum_M LCEKPFTANAAEADEIAQLAATTDRVVMEAFHYRYHPLTLRIEQILASGE
MAB_2306c|M.abscessus_ATCC_199 LVEKTFTATVSGAQEVIDIARARGVFAMEAMWTRFQPAIVAAKDLVDDGA
: : .: : : . * . . *
Mflv_2613|M.gilvum_PYR-GCK LGALHTVRSTTMDP--APPPMDYIRG--------SGGIFRDCAVHDFDVI
Mvan_3968|M.vanbaalenii_PYR-1 LGALHTVRSTTMDP--APPPMDYIKG--------SGGIFRDCAVHDFDVI
MAV_2643|M.avium_104 LGSQYLARVSRSAS--YWHPSHPLQAHWMYDREQGGGYLAGMLVHDLDFL
TH_3104|M.thermoresistible__bu IGTPRHLSWTFFGAGLRGRPHGWINE-----RDTGGGWIGANGAHLIDYT
MSMEG_3300|M.smegmatis_MC2_155 VG--KVLSTNIVGSGMAWAPGAPAAQAYAFDARNGVTTLTVSTAHALDAL
MMAR_2628|M.marinum_M LGTLQRVETSMCFPLPKFSDIRYNYA-------LAGGATMDAGCYAVHMA
MAB_2306c|M.abscessus_ATCC_199 IGEVRQVQADLGVDRPFDREDRLFNP------ALGGGALLDLGVYVVSLA
:* . : .
Mflv_2613|M.gilvum_PYR-GCK RWVTGQNVVEVYATG-SVQGDPLFTEYG-----DVDTAAIVVRFDGGALG
Mvan_3968|M.vanbaalenii_PYR-1 RWVTGQNVVDVYATG-SVQGDPRFAEYG-----DVDTAAVVVRFDGGALG
MAV_2643|M.avium_104 TSLLGRPVSVCAEVR-TSDPVRELPDGGTLPVTADDTAALLMRMESGVTV
TH_3104|M.thermoresistible__bu RYLFGSEITGCGGVARIEDPHRPDPQGRPRRATAEDAYSAWFVTENGCTA
MSMEG_3300|M.smegmatis_MC2_155 SYVLGDISSVTSTLG-VGNDTITLDDGSTTTVTSPDQVAVTAQLESGAVA
MMAR_2628|M.marinum_M RTFGGGTPEVVSAQAKRRDSE------------VDRAMTAELRFPAGHSG
MAB_2306c|M.abscessus_ATCC_199 QYFLGDPAAVVAHGSLFPTGV-------------DAEAGLLLRYDDGRTA
. * *
Mflv_2613|M.gilvum_PYR-GCK VVSAARYNGRGYDCRLEVHGFDDTVVAG-------WDQGAPVRNADP---
Mvan_3968|M.vanbaalenii_PYR-1 VVSAARYNGRGYDCRLEVHGFDDTVVAG-------WDQGAPVRNADPDFS
MAV_2643|M.avium_104 ILSLSVMGAHADHYRLELFGSDGTIIGDGDLRSAAYSLGAATDAGLSPLT
TH_3104|M.thermoresistible__bu THDTAFAAAVALPPRMVLTGSAGALELIG-------DSRLIVHRADADPM
MSMEG_3300|M.smegmatis_MC2_155 SVFYRGGLSRAGNLRWEINGTHGDLLLTSPAPNGNIQATELVLAGANGSA
MMAR_2628|M.marinum_M RIQCSMWSSHLLNMSARVVGDRGELRVLN------PVVPQLFHRLTVQSA
MAB_2306c|M.abscessus_ATCC_199 TLLCSLLHHTPG--QARIFGTEGWIDILP-------RFHHPREIVLHRKG
: * . :
Mflv_2613|M.gilvum_PYR-GCK -ANDFPTGQP--HHFFMDRFTEAFRTELSSFVDVVEGG--PNLGATVADA
Mvan_3968|M.vanbaalenii_PYR-1 SPGAFPAGPP--HHFFMDRFTEAFRAELRAFVDVVEGG--PIRGATVADA
MAV_2643|M.avium_104 VDEREPAHPERLPGGLAGHASRAMALMLQDWLPAFDGG--PSGAATFEDG
TH_3104|M.thermoresistible__bu THEFPPAPPR-------SFYEPALTPWLEQVADALRTG--RPATPSFDDG
MSMEG_3300|M.smegmatis_MC2_155 THLEPIHTHDAHPETGLSGPANTVANLYRAFAHDQLLG--TAAAPTFGDA
MMAR_2628|M.marinum_M IGRRVERFPR----------RASYAYQLDAFTGAILRG--EAVKTTPQDA
MAB_2306c|M.abscessus_ATCC_199 AAPEPMVRPP---------VGGGYSHELAEVTECLLNGRAQSSVMPLADT
* . *
Mflv_2613|M.gilvum_PYR-GCK VEVAWIAEAATESLRRGVPVTIDSVRKEAQQ
Mvan_3968|M.vanbaalenii_PYR-1 VEVAWIAEAATESLRRGVPVTIESVRKETQQ
MAV_2643|M.avium_104 LLSLAVIDAAHRSAEGGGWEQVQV-------
TH_3104|M.thermoresistible__bu VAVAEVMDRLRANVIEQVMQ-----------
MSMEG_3300|M.smegmatis_MC2_155 VALHRLIAGIEHVNTESHRKY----------
MMAR_2628|M.marinum_M VQNMTVIDAIYRAAGLPLRNPS---------
MAB_2306c|M.abscessus_ATCC_199 LAVQRVLNTACEQLGVDHTEDPADLD-----
: :