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MTTTVRTGVRSAPHPEADTRPRWVTPALLALLASTAVLYLWGLGSSGWANQYYAAAAQAGTQDWKAWLFG SLDAGNAITVDKPPASLWVMALSGRVFGFSPFTMLLPQALMGVASVAVLVAAVRRLSGPGAGLIAGAALA VTPVAALMFRYNNPDALLVLLLVVAAYLMVRAIQTGGTRWVVLVGVVLGVAFLTKMLQAFLVVPGLALAF LVAAPVGVWARVGKLAAGGVAMIATAGSFLTLVSVWPADARPYIGGSTDNSLLQLALGYNGIQRVMGGQG GPGGPPGGGLGGPPAGGPGGPGGGANLFFGGEPDIGRLFGASMGAEASWLLPAALIGLVAALWITRRAAR TDAIRAGLLLWGGWVLVTGVVFSYMDGIIHPYYTVALAPGIAALIGISVVTLWRGRGLFAPRLILAAMSA VTGVWAFVLLDRTPEWQPWLRWVVLVGSIAVAVVFSAGAHRLGRATVAVAAAAIVLGAAAPLAYALETAL HSHAGGAMAMSGPARDSGFGGPGGPAGPDGDNTELQELVRSADNRWAAAGVGSMLTGDLQLRTGASVMAI GGFTGGDNAPTLEQFQQYVADGQVRYFIAGGHGGPGGGARSASQITAWVTQTFAPRDVGGTAVYDLQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2269 | - | - | 100% (628) | glycosyl transferase family protein |
| M. gilvum PYR-GCK | Mflv_0468 | - | 9e-08 | 26.10% (387) | hypothetical protein Mflv_0468 |
| M. gilvum PYR-GCK | Mflv_4805 | - | 4e-05 | 64.71% (34) | hypothetical protein Mflv_4805 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1661c | - | 5e-08 | 24.94% (421) | hypothetical protein Mb1661c |
| M. tuberculosis H37Rv | Rv1635c | - | 5e-08 | 24.94% (421) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0927 | - | 1e-148 | 45.60% (625) | glycosyltransferase |
| M. marinum M | MMAR_2097 | - | 7e-07 | 28.78% (205) | PE-PGRS family protein, PE_PGRS33 |
| M. avium 104 | MAV_1126 | - | 4e-05 | 27.59% (232) | dolichyl-phosphate-mannose-protein mannosyltransferase |
| M. smegmatis MC2 155 | MSMEG_4986 | - | 0.0 | 64.88% (635) | glycosyl transferase, family protein 39 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3247 | - | 8e-07 | 28.23% (209) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_4425 | - | 0.0 | 80.13% (634) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2269|M.gilvum_PYR-GCK --------MTTTVRTGVRSAP--HPEADTRPRWVTPALLALLASTAVLYL
Mvan_4425|M.vanbaalenii_PYR-1 --------MTATADLAPRTTADAEPVATERPRWMWPALLALLGATAVLYL
MSMEG_4986|M.smegmatis_MC2_155 ---------MTTVEQARPSAALETPAPQAR--WIRPAYWAMLVGTAVLYL
MAB_0927|M.abscessus_ATCC_1997 ---------MSVLSTARGRAR------------EPLSVTLLLVGTAVAYL
Mb1661c|M.bovis_AF2122/97 --------MHASRPGAPPHAG-----------LPSRRTAGDQDHRADPKV
Rv1635c|M.tuberculosis_H37Rv --------MHASRPGAPPHAG-----------LPSRRTAGDQDHRADPKV
MMAR_2097|M.marinum_M ---------MSYMFAVPDTVA--------------AAAADLAGIGSTLNA
MUL_3247|M.ulcerans_Agy99 ---------MSYMFAVPDTVA--------------AAAADLAGIGSTLNA
MAV_1126|M.avium_104 MHTDGAETERVVPVVSPGPLVPAADFGPTDDVRGWVVTGVVTLVAAVTRF
:
Mflv_2269|M.gilvum_PYR-GCK WGLGSSGWANQYYAAAAQAGTQDWKAWLFGSLDAGNAITVDK-PPASLWV
Mvan_4425|M.vanbaalenii_PYR-1 WGLGSAGWANQYYAAAAQAGTQDWKAWLFGSLDAGNAITVDK-PPAALWV
MSMEG_4986|M.smegmatis_MC2_155 WGLGSKGWANSYYAAAAQAATQSWKAWLFGSLDAGNAITVDK-PPAAMWA
MAB_0927|M.abscessus_ATCC_1997 INLASNGWANSFYSAAVQAGSVSWKAGFFGSSDAANSITVDK-PPAALWL
Mb1661c|M.bovis_AF2122/97 TRIMSASTLEQPAAAHVDELVARMRGRLLDP------LAIAV-LAAVISG
Rv1635c|M.tuberculosis_H37Rv TRIMSASTLEQPAAAHVDELVARMRGRLLDP------LAIAV-LAAVISG
MMAR_2097|M.marinum_M ATAAAAAPTTGVLAAGADQVSAAVAALFSGHALDYQALSTQV-AAFHTQF
MUL_3247|M.ulcerans_Agy99 ATAAAAAPTTGVLAAGADQVSAAVAALFPGHALDYQALSTQV-AAFHTQF
MAV_1126|M.avium_104 VNLGSPTDGGTPVFDEKHYAPQAWQVLHNHGVEDNPGFGLVVHPPVGKQL
: . : .
Mflv_2269|M.gilvum_PYR-GCK MALSGRVFGFSPFTMLLPQALMGVASVAVLVAAVRRLS-GPGAGLIAGAA
Mvan_4425|M.vanbaalenii_PYR-1 MALSGRLFGFSPFTMLLPQALMGVASVAVLFAAVRRVS-GPGAGLIAGAA
MSMEG_4986|M.smegmatis_MC2_155 MGLSGRLFGFNEFTMLLPEALMGVAAVAVLYATVRRTS-GPVAGLVAGTA
MAB_0927|M.abscessus_ATCC_1997 MELSVRVFGLSGWSILVPQVLLGVASVGLLYATVRRYF-GHRAGLLAGLV
Mb1661c|M.bovis_AF2122/97 AWASRPSLWFDEGATISASASRTLPELWSLLGHIDAVH-GLYYLLMHGWF
Rv1635c|M.tuberculosis_H37Rv AWASRPSLWFDEGATISASASRTLPELWSLLGHIDAVH-GLYYLLMHGWF
MMAR_2097|M.marinum_M VEAVTG----AGNAYAAAEAANASPLLGISQDMLNAVN-GPTEALLGRPL
MUL_3247|M.ulcerans_Agy99 VEAVTG----AGNAYAAAEAANASPLLGISQDMLNAVN-GPTEASLGRPL
MAV_1126|M.avium_104 IAIGEALFGYNGVGWRFTGALLGVVMVALVVRIVRRISRSTLVGAIAGVL
. . : : . :
Mflv_2269|M.gilvum_PYR-GCK LAVTPVAALMFRYNNPDALLVLLLVVAAYLMVRAIQTGGTR----WVVLV
Mvan_4425|M.vanbaalenii_PYR-1 LAVTPVAALMFRYNNPDALLVLLLVVAAYLTVRAIQTGGTR----WMVLV
MSMEG_4986|M.smegmatis_MC2_155 LALTPVATVMFRYNNPDALLVLLLVVAAYFMVRAIGASGARAATGWVVLC
MAB_0927|M.abscessus_ATCC_1997 LAVTPVAVLMFRFNNPDALLVFLMIAAVWAMMRAVEDGRTR----WMLLV
Mb1661c|M.bovis_AF2122/97 AIFPPTELWSR---LPSCLAIGAAAAGVVVFAKQFSGRTTAVCAGAVFAI
Rv1635c|M.tuberculosis_H37Rv AIFPPTELWSR---LPSCLAIGAAAAGVVVFAKQFSGRTTAVCAGAVFAI
MMAR_2097|M.marinum_M IGNGADGTAPGQAGGDGGLLYGNGGAGGPGGAGGNAGLIGN-----GGAG
MUL_3247|M.ulcerans_Agy99 IGNGADGTAPEQAGGDGSLLYGNGGAGGPGGAGGNAGLIGN-----GGAG
MAV_1126|M.avium_104 VICDGVSFVASRTALLDGILTFFVVAAFGALIVDRDQVRQR---------
. : ..
Mflv_2269|M.gilvum_PYR-GCK GVVLGVAFLTKMLQAFLVVPGLALAFLVAAPVG-VWARVGKLAAGGVAMI
Mvan_4425|M.vanbaalenii_PYR-1 GIVLGFAFLTKMLQAFLVMPGLALAFLVAAPVG-LWRRIGTLLTGALAMV
MSMEG_4986|M.smegmatis_MC2_155 GCALGFAFLTKMLQAFLIVPGLALAFLVAAPVASVAKRVGILLAGGVAMA
MAB_0927|M.abscessus_ATCC_1997 GVFVGFGFLTKQLQVLLVIPPVAVTYLIAGPAG-AGKRLAQLVGSAAAAV
Mb1661c|M.bovis_AF2122/97 LPRVTWAGIEARSSALSVAAAVWLTVLLVAAVRCNTQRRWLLYALVLMLS
Rv1635c|M.tuberculosis_H37Rv LPRVTWAGIEARSSALSVAAAVWLTVLLVAAVRCNTQRRWLLYALVLMLS
MMAR_2097|M.marinum_M GSGAALGLFGG----------TGGNGGLLFGNGGTGGAAGDLASG-VGLP
MUL_3247|M.ulcerans_Agy99 GSGAALGLFGGSGAALGLFGGTGGNGGLLFGDGGTGGAAGDLASG-VGLP
MAV_1126|M.avium_104 ---LHTALLQGRSADTVWGPRLGVRWWRFGAGVLLGLACGTKWSGLYFVL
. :
Mflv_2269|M.gilvum_PYR-GCK ATAGSFLTLVSVWPADARPYIGGSTDNSLLQLALGYNGIQRVMGGQGGP-
Mvan_4425|M.vanbaalenii_PYR-1 ATAGSFLAMVSLWPADSRPYIGGSTDNSLLQLALGYNGIQRVMGGEGGP-
MSMEG_4986|M.smegmatis_MC2_155 VSAGWYLALVALWPAGSRPYIAGSTDNSLLQLAFGYNGIERIVGRGGGPG
MAB_0927|M.abscessus_ATCC_1997 VSAGWWIAAVELWPPGSRPWIGGSPDNSILELTLGYNGLGRINGNETGS-
Mb1661c|M.bovis_AF2122/97 ILVSINLALLVPAYATMVPLLASG--KSRKSPVIWWTVVTAAALGAMTPF
Rv1635c|M.tuberculosis_H37Rv ILVSINLALLVPAYATMVPLLASG--KSRKSPVIWWTVVTAAALGAMTPF
MMAR_2097|M.marinum_M GGAGGHAGLFGIGGAGGE--GGNSATTAGVGGAGGAGGLLVGAGGHGGTG
MUL_3247|M.ulcerans_Agy99 GGAGGHAGLFGIGGAGGE--GGNSATTAGVGGAGGAGGLLVGAGGHGGTG
MAV_1126|M.avium_104 FFAAMSLAFDVAAR-------------RQYQVTRPWLGVVRRDLLPTGYA
.. . :
Mflv_2269|M.gilvum_PYR-GCK -GGPPGGGLGGPPAGGPGGPGGGAN-LFFGGEPDIGR-LFGASMGAEASW
Mvan_4425|M.vanbaalenii_PYR-1 -GGGAG-----APPGGPGGPGGGAN-LFFGGDPGLGR-LFGASMGAEASW
MSMEG_4986|M.smegmatis_MC2_155 FGGGPG-----PGGGGPGPGGGGSRGIFHSGDPGIGR-LFNDALGTEVAW
MAB_0927|M.abscessus_ATCC_1997 ---ASG-----PREGMYGFGG------HFGSEPGIGR-LFQPALGGQIAW
Mb1661c|M.bovis_AF2122/97 ILFAHG------QVWQVGWIAG------LNRNIILDV-IHRQYFDHSVPF
Rv1635c|M.tuberculosis_H37Rv ILFAHG------QVWQVGWIAG------LNRNIILDV-IHRQYFDHSVPF
MMAR_2097|M.marinum_M GTSASG----TGATGGSGGAGG-----LLFSPGGAGG-DGGAGFSGADGG
MUL_3247|M.ulcerans_Agy99 GTSASG----TGATGGSGGAGG-----LLFSPGGAGG-DGGAGFSGADGG
MAV_1126|M.avium_104 LGFIPA------AVYLAGYAP------WFASETAIDRHEVGQTIGPRSVL
. * . :.
Mflv_2269|M.gilvum_PYR-GCK LLPAALIGLVAALWITR--RAARTDAIRAGLLLWGGWVLVTGVVFSY---
Mvan_4425|M.vanbaalenii_PYR-1 LLPAALIGLVAGLWFTR--RAPRTCAVRASLLLWGGWVLVTGVVFSF---
MSMEG_4986|M.smegmatis_MC2_155 LLPVALIGLVVLLWLTR--HTVRTSATRAGLLVWGGWLAVTGVVFSF---
MAB_0927|M.abscessus_ATCC_1997 LLPTALLLAILGIVLLR--NNSRTDARRAVLIVFGLWILTTGIVFSY---
Mb1661c|M.bovis_AF2122/97 AILAGLIVAAGIAAHLAGARGPGGDTHRLVLVSAAWIVVPTAVVLIYSAT
Rv1635c|M.tuberculosis_H37Rv AILAGLIVAAGIAAHLAGARGPGGDTHRLVLVSAAWIVVPTAVVLIYSAT
MMAR_2097|M.marinum_M AGGNGGAGGLLFGTGGGGGEGGATSPSSSTGSGGDGGIGGTSGLFGTGGT
MUL_3247|M.ulcerans_Agy99 AGGNGGAG------------------------------------------
MAV_1126|M.avium_104 PLPDAIRSLWHYTAKAFQFHAGLTNS------------------------
.
Mflv_2269|M.gilvum_PYR-GCK -----------------MDGIIHPYYTVALAPGIAALIGISVVTLWRGRG
Mvan_4425|M.vanbaalenii_PYR-1 -----------------MDGIIHPYYTVALAPGIAALIGICVVELWRGRR
MSMEG_4986|M.smegmatis_MC2_155 -----------------MDGTIHPYYTVALAPAVAALAGISVVELWRRRS
MAB_0927|M.abscessus_ATCC_1997 -----------------MQGIFHPYYSMALTPAVAALVGAGSVLGWRERE
Mb1661c|M.bovis_AF2122/97 -----------------VEPIYYPRYLILTAPAAAVILAVCVVTIAR---
Rv1635c|M.tuberculosis_H37Rv -----------------VEPIYYPRYLILTAPAAAVILAVCVVTIAR---
MMAR_2097|M.marinum_M GGAGGAAANATGGNGGAGGGGLWFGNGGAGGIGGFDAHGNGGDGGAGGNA
MUL_3247|M.ulcerans_Agy99 ------------------GGGLWFGNGGAGGIGGFDAHGDGGDGGAGGNA
MAV_1126|M.avium_104 ------------------AGNYHPWESKPWSWPMSLRPVLYAIDEQNVPG
Mflv_2269|M.gilvum_PYR-GCK LFAPRLILAAMSAVTGVWAFVLLDRTPEWQPWLRWVVLVGSIAVAVVFSA
Mvan_4425|M.vanbaalenii_PYR-1 HFAPRTTLAVMSAGTGVWAFILLDRTPDWQPWLRWVVLIGSIVAAAVIAV
MSMEG_4986|M.smegmatis_MC2_155 HVGIRLLLAAMMGLTGVWAFVLLNRTPDWWPALRWVVLIGSVVVAVLLAL
MAB_0927|M.abscessus_ATCC_1997 KSWVRACLAALLMLTAAMAWLLLGRSPEFQPWLRWAILILALLALIGLAM
Mb1661c|M.bovis_AF2122/97 KPWLIAGVVFLLAAAAFPNYFFTQRGPYAKEGWDYS--------------
Rv1635c|M.tuberculosis_H37Rv KPWLIAGVVFLLAAAAFPNYFFTQRGPYAKEGWDYS--------------
MMAR_2097|M.marinum_M GIYGGNGGAGGTGGVGVGGNLFTGGQGGAGGNAGLLAGNGGAGGNGGVRF
MUL_3247|M.ulcerans_Agy99 GIYGGNGGAGGTGGVGVGGNLFTGGQGGAGGNAGLLAGNGGAGG------
MAV_1126|M.avium_104 CGAQSCVKAEMLVGTPAMWWLAVP--------------------------
. . .
Mflv_2269|M.gilvum_PYR-GCK GAHRLGRATVAVAAAAIVLGAAAPLAYALETALHSHAGGAMAMSGPAR-D
Mvan_4425|M.vanbaalenii_PYR-1 GAHRLGRATAAVAAAAILFGAAAPAAYAIETAGNAHDG-PVAMSGPARTD
MSMEG_4986|M.smegmatis_MC2_155 RAHRPGQVTAALALAAVVLGLGSTLAYSVETVANGQSGGPLPMAGPQR-G
MAB_0927|M.abscessus_ATCC_1997 S-----RCPKAVVVAALVAALAGPVAYSAATIATPHGG-ALPSAGPEVNG
Mb1661c|M.bovis_AF2122/97 ------------QVADVISAHAKPGDCLLVDNTAGWRPGPIRALLATR--
Rv1635c|M.tuberculosis_H37Rv ------------QVADVISAHAKPGDCLLVDNTAGWRPGPIRALLATR--
MMAR_2097|M.marinum_M SGNAGAGGAGGTGGDAGMFGNGGAGGAGGDRVAGSQGNGGDGGDGGHG-G
MUL_3247|M.ulcerans_Agy99 -----------TGGDAGMFGNGGAGGAGGDRVAGSQGNGGDGGDGGHG-G
MAV_1126|M.avium_104 ------------VLVFALWRMLVRRDWRYAAVLVGYCAGWLPWFADIDRQ
:
Mflv_2269|M.gilvum_PYR-GCK SGFG-GPGGPAGPDG---DNTELQ--ELVRSADN---------------R
Mvan_4425|M.vanbaalenii_PYR-1 VDLG-GPPGPGGPGASVADNTELQ--HLVQATDS---------------R
MSMEG_4986|M.smegmatis_MC2_155 GGFG-FGGPHRGERD---DDTALR--ELISDTDN---------------R
MAB_0927|M.abscessus_ATCC_1997 GGFPEFPDMPERPHRAEFEPASKRGGSLLDGSDPGPNIVAALNDNADRYT
Mb1661c|M.bovis_AF2122/97 -------------------PAAFR--SLIDVERG----------------
Rv1635c|M.tuberculosis_H37Rv -------------------PAAFR--SLIDVERG----------------
MMAR_2097|M.marinum_M TYFG---------------SGGAGGHGGYDDSGS----------------
MUL_3247|M.ulcerans_Agy99 TYFG---------------SGGAGGHGGYDDSGS----------------
MAV_1126|M.avium_104 MYFF----------------------------------------------
Mflv_2269|M.gilvum_PYR-GCK WAAAGVGSMLTGDLQLRTGASVMAIGGFTGGDNAPTLEQFQQYVADGQVR
Mvan_4425|M.vanbaalenii_PYR-1 WAAASVGSMVAGELELQTGTSVMAIGGFTGGDNSPTLQQFQDYVADRQVR
MSMEG_4986|M.smegmatis_MC2_155 WAAASVGSWMVSDLELKTGESLMAIGGFMGADDSPTLEQFQQYVERGDVR
MAB_0927|M.abscessus_ATCC_1997 WVAAAIGSNQASGYQLATRRPVMPIGGFNGTDPSPTLAQFQQYVADGQIH
Mb1661c|M.bovis_AF2122/97 TYGPKVGTLWDGHVAVWLTTAKIDK-----CPTLWTIANRDKSLPDHQVG
Rv1635c|M.tuberculosis_H37Rv TYGPKVGTLWDGHVAVWLTTAKIDK-----CPTLWTIANRDKSLPDHQVG
MMAR_2097|M.marinum_M --GGQGGHGGDGGAAGTIGNGGDGGTGGDALVSGGTGGDGGDGGD---AR
MUL_3247|M.ulcerans_Agy99 --GGQGGHGGDGGAAGTIGNGGDGGTGGDALVSGGTGGDGGDGGDGGDAR
MAV_1126|M.avium_104 -YAATMAPFLAMAIALICGDILYAPTATGMLRANSERRTLGLIAVCCYVA
. .
Mflv_2269|M.gilvum_PYR-GCK YFIAG---GHG--GPGGG-ARSASQITAWVTQTFAPRDVGGTAVYDLQR-
Mvan_4425|M.vanbaalenii_PYR-1 YFIAG---GHG--GPGRN-SGSAGDITAWVEQNFAPMDVGGTTVYDLQR-
MSMEG_4986|M.smegmatis_MC2_155 YFLAP---AEGRRGPGGFRHGSAGDITNWVKENFPKTEVGGVTVYDLQSR
MAB_0927|M.abscessus_ATCC_1997 YFIDGERGSHGDEGFGPPGSETSKSIREWVQRTFTKKTIDDVEVYDLTGH
Mb1661c|M.bovis_AF2122/97 EMLSP--------GTGFGRTPVYRFPSYLGFRIVERWQFHYSQVVKSTR-
Rv1635c|M.tuberculosis_H37Rv EMLSP--------GTGFGRTPVYRFPSYLGFRIVERWQFHYSQVVKSTR-
MMAR_2097|M.marinum_M EIGNG----------GNGGNAGAGATAGNEGTGGTGGQLIGVSGTDGST-
MUL_3247|M.ulcerans_Agy99 EIGNG----------GNGGNAGAGATAGNEGTGGTGGQLIGVSGTDGST-
MAV_1126|M.avium_104 LVVTN----------------FAWLFPVLTGLPISQQTWNMEIWLPSWR-
.