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SYMFAVPDTVAAAAADLAGIGSTLNAATAAAAAPTTGVLAAGADQVSAAVAALFSGHALDYQALSTQVAA FHTQFVEAVTGAGNAYAAAEAANASPLLGISQDMLNAVNGPTEALLGRPLIGNGADGTAPGQAGGDGGLL YGNGGAGGPGGAGGNAGLIGNGGAGGSGAALGLFGGTGGNGGLLFGNGGTGGAAGDLASGVGLPGGAGGH AGLFGIGGAGGEGGNSATTAGVGGAGGAGGLLVGAGGHGGTGGTSASGTGATGGSGGAGGLLFSPGGAGG DGGAGFSGADGGAGGNGGAGGLLFGTGGGGGEGGATSPSSSTGSGGDGGIGGTSGLFGTGGTGGAGGAAA NATGGNGGAGGGGLWFGNGGAGGIGGFDAHGNGGDGGAGGNAGIYGGNGGAGGTGGVGVGGNLFTGGQGG AGGNAGLLAGNGGAGGNGGVRFSGNAGAGGAGGTGGDAGMFGNGGAGGAGGDRVAGSQGNGGDGGDGGHG GTYFGSGGAGGHGGYDDSGSGGQGGHGGDGGAAGTIGNGGDGGTGGDALVSGGTGGDGGDGGDAREIGNG GNGGNAGAGATAGNEGTGGTGGQLIGVSGTDGST*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2097 | - | - | 100% (595) | PE-PGRS family protein, PE_PGRS33 |
| M. marinum M | MMAR_0478 | - | e-171 | 51.37% (695) | PE-PGRS family protein |
| M. marinum M | MMAR_2053 | - | e-168 | 49.13% (751) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1360c | PE_PGRS24 | 1e-173 | 56.16% (625) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-109 | 43.96% (621) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1325c | PE_PGRS24 | 1e-173 | 56.16% (625) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 5e-12 | 37.50% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 3e-45 | 34.99% (403) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 5e-26 | 45.12% (164) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-97 | 39.65% (623) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 7e-41 | 39.66% (295) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3247 | - | 0.0 | 73.07% (609) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-107 | 42.58% (620) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2097|M.marinum_M --------------------------------------------------
MUL_3247|M.ulcerans_Agy99 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_2097|M.marinum_M --------------------------------------------------
MUL_3247|M.ulcerans_Agy99 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_2097|M.marinum_M --------------------------------------------------
MUL_3247|M.ulcerans_Agy99 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_2097|M.marinum_M --------------------------------------------------
MUL_3247|M.ulcerans_Agy99 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_2097|M.marinum_M --------------------------------------------------
MUL_3247|M.ulcerans_Agy99 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 EAA-------------------------------------LANAGLSAVS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS
MMAR_2097|M.marinum_M -------MSYMFAVPDTVAAAAADLAGIGSTLNAATAAAAAPTTGVLAAG
MUL_3247|M.ulcerans_Agy99 -------MSYMFAVPDTVAAAAADLAGIGSTLNAATAAAAAPTTGVLAAG
Mb1360c|M.bovis_AF2122/97 -------MSFVIAAPETLVRAASDLANIGSTLGAANAAALGPTTELLAAG
Rv1325c|M.tuberculosis_H37Rv -------MSFVIAAPETLVRAASDLANIGSTLGAANAAALGPTTELLAAG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ
MLBr_01183|M.leprae_Br4923 ------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPA
MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
MMAR_2097|M.marinum_M ADQVSAAVAALFSGHALDYQALSTQVAAFHTQFVEAVTGAGNAYAAAEAA
MUL_3247|M.ulcerans_Agy99 ADQVSAAVAALFPGHALDYQALSTQVAAFHTQFVEAVTGAGNAYAAAEAA
Mb1360c|M.bovis_AF2122/97 ADEVSAAIASLFAAHGQAYQAVSAQMSAFHAQFVQTFTAGAGAYASAEAA
Rv1325c|M.tuberculosis_H37Rv ADEVSAAIASLFAAHGQAYQAVSAQMSAFHAQFVQTFTAGAGAYASAEAA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG---APGVAGATGAT
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG---APGVAGATGAT
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDG-GTGGTGGTGGGT
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG--------------GNGGHGGGT
MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGN-QVMSPSGNVDSF
MLBr_01183|M.leprae_Br4923 ADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETA
MAV_4827|M.avium_104 REG-AADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAA
: .
MMAR_2097|M.marinum_M NASPLLGISQDMLNAVNGPTEALLGRPLIGNGADGT--------------
MUL_3247|M.ulcerans_Agy99 NASPLLGISQDMLNAVNGPTEASLGRPLIGNGADGT--------------
Mb1360c|M.bovis_AF2122/97 AAAPLEG----LLNIVNTPTQLLLGRPLIGNGANGAP-------------
Rv1325c|M.tuberculosis_H37Rv AAAPLEG----LLNIVNTPTQLLLGRPLIGNGANGAP-------------
Mflv_5091|M.gilvum_PYR-GCK GVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 GVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNV
TH_3810|M.thermoresistible__bu GIIS--------------------LLSLAGNGGNGG--------------
MAB_4284c|M.abscessus_ATCC_199 NRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------IAS
MLBr_01183|M.leprae_Br4923 NHDSL---------------------------------------------
MAV_4827|M.avium_104 ALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP------------
MMAR_2097|M.marinum_M APGQAGGDGGLLYG------------------------------------
MUL_3247|M.ulcerans_Agy99 APEQAGGDGSLLYG------------------------------------
Mb1360c|M.bovis_AF2122/97 GTGQAGGAGGLLYG------------------------------------
Rv1325c|M.tuberculosis_H37Rv GTGQAGGAGGLLYG------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG---------------
Mvan_1264|M.vanbaalenii_PYR-1 AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG---------------
MSMEG_0868|M.smegmatis_MC2_155 TVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG
TH_3810|M.thermoresistible__bu -NGYRTTDNNALDGGHGG--------------------------------
MAB_4284c|M.abscessus_ATCC_199 GQGSTAVNGDVRDSNIIN--------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -DVYKQQIRAESYGDAAG--------------------------------
MMAR_2097|M.marinum_M -------------------------------------------NGGAGGP
MUL_3247|M.ulcerans_Agy99 -------------------------------------------NGGAGGP
Mb1360c|M.bovis_AF2122/97 -------------------------------------------NGGAGGS
Rv1325c|M.tuberculosis_H37Rv -------------------------------------------NGGAGGS
Mflv_5091|M.gilvum_PYR-GCK -AVGAAGAAG------TVGTAGATGGTG---------------TGANGGA
Mvan_1264|M.vanbaalenii_PYR-1 -AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGA
MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGH
TH_3810|M.thermoresistible__bu -------------------------------------------NGGNVGF
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------ADHGSNVGV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------------------------QLSAMVAGL
MMAR_2097|M.marinum_M ------GGAGGNAG--------------LIGNGGAGGSG---AALGLFGG
MUL_3247|M.ulcerans_Agy99 ------GGAGGNAG--------------LIGNGGAGGSG---AALGLFGG
Mb1360c|M.bovis_AF2122/97 GAPGQAGGPGGAAG--------------LFGNGGAGGAGGDGPGNGAAGG
Rv1325c|M.tuberculosis_H37Rv GAPGQAGGPGGAAG--------------LFGNGGAGGAGGDGPGNGAAGG
Mflv_5091|M.gilvum_PYR-GCK GGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ
Mvan_1264|M.vanbaalenii_PYR-1 GQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ
MSMEG_0868|M.smegmatis_MC2_155 STGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEI
TH_3810|M.thermoresistible__bu FSLFNLGG--------------------AGGWGGSGVDG-----------
MAB_4284c|M.abscessus_ATCC_199 DQSQTRVGGDYTN---------------VSGHGSADIDKSVTVVDDHSQR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 EKLESLPGGLLLVG---------------SGVDVAPLKQVLQTTTFLDVS
MMAR_2097|M.marinum_M ----------TGGNGGLLFGNG----------------------------
MUL_3247|M.ulcerans_Agy99 SGAALGLFGGTGGNGGLLFGDG----------------------------
Mb1360c|M.bovis_AF2122/97 ----------AGGAGGLLFGSG----------------------------
Rv1325c|M.tuberculosis_H37Rv ----------AGGAGGLLFGSG----------------------------
Mflv_5091|M.gilvum_PYR-GCK --GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG----------
Mvan_1264|M.vanbaalenii_PYR-1 --GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG----------
MSMEG_0868|M.smegmatis_MC2_155 YSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT
TH_3810|M.thermoresistible__bu ----------VDVVGGNP--------------------------------
MAB_4284c|M.abscessus_ATCC_199 NTTNINDSFNTDRSTNIGSGNTTNTEIGSHN-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VAEEPETALARGAALAAANAPLFAS-------------------------
MMAR_2097|M.marinum_M ---------GTGGAAG-----------------------------DLASG
MUL_3247|M.ulcerans_Agy99 ---------GTGGAAG-----------------------------DLASG
Mb1360c|M.bovis_AF2122/97 ---------GAGGPGG-----------------------------VGNTG
Rv1325c|M.tuberculosis_H37Rv ---------GAGGPGG-----------------------------VGNTG
Mflv_5091|M.gilvum_PYR-GCK ---LQGGKGGDGGAGGKGGDADSMGS------------------AGATGG
Mvan_1264|M.vanbaalenii_PYR-1 ---LQGGQGGDGGTGGTGGDATSMGE------------------AGATGG
MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGA
TH_3810|M.thermoresistible__bu ----------DGGTPG------------------------------AHGE
MAB_4284c|M.abscessus_ATCC_199 --------QANIGTS------------------------------TSAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------STAALAY-----------------------------AQDPG
MMAR_2097|M.marinum_M VGLPGGAGGHAGLFG-----------------------------------
MUL_3247|M.ulcerans_Agy99 VGLPGGAGGHAGLFG-----------------------------------
Mb1360c|M.bovis_AF2122/97 TGGLGGDGGAAGLFG-----------------------------------
Rv1325c|M.tuberculosis_H37Rv TGGLGGDGGAAGLFG-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK KGGNGGNGGRGGLFG---------------KGGNAGNGAD----------
Mvan_1264|M.vanbaalenii_PYR-1 KGGNGGNGGRGSLFG---------------RGGNAGNGGN----------
MSMEG_0868|M.smegmatis_MC2_155 VGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG
TH_3810|M.thermoresistible__bu SHTPGVYTDRQ---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SAAVGGNAGLAGNAG-----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TGAVDQYSLPDYLYVP----------------------------------
MMAR_2097|M.marinum_M -----------IGGAGGEGGNSATTAGVGGAGGAGGL-------------
MUL_3247|M.ulcerans_Agy99 -----------IGGAGGEGGNSATTAGVGGAGGAGGL-------------
Mb1360c|M.bovis_AF2122/97 -----------AGGIGGAGG-PGFNGGAGGAGGRSGLF------------
Rv1325c|M.tuberculosis_H37Rv -----------AGGIGGAGG-PGFNGGAGGAGGRSGLF------------
Mflv_5091|M.gilvum_PYR-GCK ------------GGTGGAGGAGGTGG-TGGAGGTGG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------GGTGGNGGNGGTGG-TGGNGGTGG--------------
MSMEG_0868|M.smegmatis_MC2_155 PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG
TH_3810|M.thermoresistible__bu ----------------GEDGEDGTGTGIGGRGGNGG--------------
MAB_4284c|M.abscessus_ATCC_199 --------------LAGNAGLAGNAGLAGNAGLAGN--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------VDPEPGDDELAYSAVGEEDAESPT------------
MMAR_2097|M.marinum_M ---LVGAGGHGGTGGTSASG-TGATGGSGGAGGLLFSPGGAGGDGGAGFS
MUL_3247|M.ulcerans_Agy99 ---LVGAGGHGGTGGTSASG-TGATGGSGGAGGLLFSPGGAGGDGGAGFS
Mb1360c|M.bovis_AF2122/97 --EVLAAGGAGGTGGLSVNGGTGGTGGTGGGGG-LFSNGGAGGAGGFGVS
Rv1325c|M.tuberculosis_H37Rv --EVLAAGGAGGTGGLSVNGGTGGTGGTGGGGG-LFSNGGAGGAGGFGVS
Mflv_5091|M.gilvum_PYR-GCK ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
Mvan_1264|M.vanbaalenii_PYR-1 ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
MSMEG_0868|M.smegmatis_MC2_155 QTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGR
TH_3810|M.thermoresistible__bu --SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGH
MAB_4284c|M.abscessus_ATCC_199 -AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA----GNAGLAGNAGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --VVIEKLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTT
MMAR_2097|M.marinum_M GADGGAGGNGGAGGLLFGTGGGGGEGGATSPSSSTGSGGDGGIGGTSGLF
MUL_3247|M.ulcerans_Agy99 GADGGAGGNGGAG-------------------------------------
Mb1360c|M.bovis_AF2122/97 GSAGGNGGTGGDGGIFTGNGGTGG--------------------------
Rv1325c|M.tuberculosis_H37Rv GSAGGNGGTGGDGGIFTGNGGTGG--------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAGGTG----GDGGTGGT-------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGDGGTG----GTGGTGGT-------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGDGALGGNGGTGGVGLGNGGKGGN-------------------------
TH_3810|M.thermoresistible__bu GGRGGFLGIGGSG-------GWGGH-------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAG----NAGLAGN-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GTVALQPTPNQHLIVPTEQAPAPPP-------------------------
MMAR_2097|M.marinum_M GTGGTGGAGGA----AANATGGNGGAGGGG------------LWFGNGGA
MUL_3247|M.ulcerans_Agy99 ---------------------------GGG------------LWFGNGGA
Mb1360c|M.bovis_AF2122/97 -AGGTGTGNQL----VGGEGGAGGAGGNAG------------ILFGAGGI
Rv1325c|M.tuberculosis_H37Rv -TGGTGTGNQL----VGGEGGAGGAGGNAG------------ILFGAGGI
Mflv_5091|M.gilvum_PYR-GCK --GGTGGTG---------GTGGTGGTGGAG-----------DGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 --GGTGGTG---------GTGGTGGTGGAG-----------DGLGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 --GGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGN
TH_3810|M.thermoresistible__bu --GGNGGD-----------TDADGGNGGDG---------------GNGGS
MAB_4284c|M.abscessus_ATCC_199 --AGLAGNAG--------LAGNAGLAGNAG-------------LAGNAGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------VQASAPQPKISVP-----------EPVAAPKPL
MMAR_2097|M.marinum_M GG------------------------------------IGG-----FDAH
MUL_3247|M.ulcerans_Agy99 GG------------------------------------IGG-----FDAH
Mb1360c|M.bovis_AF2122/97 GG------------------------------------TGGTGLGAPDPG
Rv1325c|M.tuberculosis_H37Rv GG------------------------------------TGGTGLGAPDPG
Mflv_5091|M.gilvum_PYR-GCK GG----TGGQGGQGGQGG-----------------TGGTGGQGG-LGGGG
Mvan_1264|M.vanbaalenii_PYR-1 GG----TGGFGGQGGQGG-----------------TGGTGGQGG-LGGVG
MSMEG_0868|M.smegmatis_MC2_155 GGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATN
TH_3810|M.thermoresistible__bu AG---------------------------------RGGTGGLRGVFGING
MAB_4284c|M.abscessus_ATCC_199 AG---------------------------------NAAVAGNAAVAGNAA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 SP-----------------------------------PVAAPLPAAPPPA
MMAR_2097|M.marinum_M GNG-----------------------GDGGAG--GNAGIYGGNGGAGGTG
MUL_3247|M.ulcerans_Agy99 GDG-----------------------GDGGAG--GNAGIYGGNGGAGGTG
Mb1360c|M.bovis_AF2122/97 GTG-----------------------GKGGVGGIGGAGALFGPGGAGGTG
Rv1325c|M.tuberculosis_H37Rv GTG-----------------------GKGGVGGIGGAGALFGPGGAGGTG
Mflv_5091|M.gilvum_PYR-GCK GTG-----------------------GQGGTGGTGGQGGTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GTG-----------------------GTGGTGGTGGQGGTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANG
TH_3810|M.thermoresistible__bu GNG------------------------RAGLGGRGXXXXGGGVGAAVRSG
MAB_4284c|M.abscessus_ATCC_199 VAG------------------------NAAVGGVLNTGVSGAIGGSSHVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 APP-----------------------LPEAPPIPAAPPVVPVPVVVPPVP
MMAR_2097|M.marinum_M --------GVGVG-GNLFTGGQGGAGGN--AGLLAGNGGAGGNGGVRFSG
MUL_3247|M.ulcerans_Agy99 --------GVGVG-GNLFTGGQGGAGGN--AGLLAGNGGAGG--------
Mb1360c|M.bovis_AF2122/97 --------GFGASSADQMAGGIGGSGGSGGAAKLIGDGGAGGTGGDSVRG
Rv1325c|M.tuberculosis_H37Rv --------GFGASSADQMAGGIGGSGGSGGAAKLIGDGGAGGTGGDSVRG
Mflv_5091|M.gilvum_PYR-GCK --------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGA
Mvan_1264|M.vanbaalenii_PYR-1 --------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGA
MSMEG_0868|M.smegmatis_MC2_155 PSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGG
TH_3810|M.thermoresistible__bu ---------------NGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSR
MAB_4284c|M.abscessus_ATCC_199 ---------GAINESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVP
MMAR_2097|M.marinum_M NA------------------------GAGGAGGTGGDAGMFGNGGAGGAG
MUL_3247|M.ulcerans_Agy99 ---------------------------------TGGDAGMFGNGGAGGAG
Mb1360c|M.bovis_AF2122/97 ---------------------------AAGSGGTGGTGGLIGDGGAGGAG
Rv1325c|M.tuberculosis_H37Rv ---------------------------AAGSGGTGGTGGLIGDGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK GG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQG
Mvan_1264|M.vanbaalenii_PYR-1 GG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQG
MSMEG_0868|M.smegmatis_MC2_155 DGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVA
TH_3810|M.thermoresistible__bu EG------------------------IMPSSRAASARAG-----------
MAB_4284c|M.abscessus_ATCC_199 GG--------------------GISESLGGSGSVGGSTAVGGGAHTGVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 QS-------------------------PPQHQTPPGEGTPPKPDGPGNYG
MMAR_2097|M.marinum_M GD-------------RVAGSQGNG-------GDGGDGGHG----------
MUL_3247|M.ulcerans_Agy99 GD-------------RVAGSQGNG-------GDGGDGGHG----------
Mb1360c|M.bovis_AF2122/97 GTG--------IEFGSVGGAGGAGGNAAGLSGAGGAGGAGGF--------
Rv1325c|M.tuberculosis_H37Rv GTG--------IEFGSVGGAGGAGGNAAGLSGAGGAGGAGGF--------
Mflv_5091|M.gilvum_PYR-GCK ATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG----------
Mvan_1264|M.vanbaalenii_PYR-1 ATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG----------
MSMEG_0868|M.smegmatis_MC2_155 GNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHG
TH_3810|M.thermoresistible__bu ----------------AACASSTSRSRRSFCCSRA---------------
MAB_4284c|M.abscessus_ATCC_199 GVS----------TGVGVGSHVGGGISESLGGSGSVGGSTAVG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GGHVP--------TPGAGGSGGSGGGHVPTPGAGGSGGSG----------
MMAR_2097|M.marinum_M ---GTYFGSGGAGGHGG--YDDSGSG--------GQGGH-----------
MUL_3247|M.ulcerans_Agy99 ---GTYFGSGGAGGHGG--YDDSGSG--------GQGGH-----------
Mb1360c|M.bovis_AF2122/97 ---GETAGDGGAGGNAGLLNGDGGAGGAGGLGIAGDGGN-----------
Rv1325c|M.tuberculosis_H37Rv ---GETAGDGGAGGNAGLLNGDGGAGGAGGLGIAGDGGN-----------
Mflv_5091|M.gilvum_PYR-GCK -TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGE
Mvan_1264|M.vanbaalenii_PYR-1 -TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGD
MSMEG_0868|M.smegmatis_MC2_155 AITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --GGAHTGVGGGVNTGVGVGSHVGGGISESLGGSGSVG-------GSTAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---GGHVPTPGTGGPGGTGGSGGGHVPTPGAGTPGGSGG-----------
MMAR_2097|M.marinum_M -GGDGGAAGTIGNGGDGGTGG----------DALVSGGTGGDGGDGGD--
MUL_3247|M.ulcerans_Agy99 -GGDGGAAGTIGNGGDGGTGG----------DALVSGGTGGDGGDGGDGG
Mb1360c|M.bovis_AF2122/97 -GGKGGKAGMVGNGGDGGAGG----------ASVVAN--GGVGGSGGN--
Rv1325c|M.tuberculosis_H37Rv -GGKGGKAGMVGNGGDGGAGG----------ASVVAN--GGVGGSGGN--
Mflv_5091|M.gilvum_PYR-GCK DGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGA
Mvan_1264|M.vanbaalenii_PYR-1 AGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGS
MSMEG_0868|M.smegmatis_MC2_155 GGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGAHTSAINDALGGSGSVGG----------STAVGGGAHTSAINESMNS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -GHLPFPGAGSTPGGSGGGHLP---------TPGAGTPGGGLGGFGGG--
MMAR_2097|M.marinum_M ---------AREIGNGGNGGNAGAGATAGNEGTGGTGGQLIGVSGTDGST
MUL_3247|M.ulcerans_Agy99 D--------AREIGNGGNGGNAGAGATAGNEGTGGTGGQLIGVSGTDGST
Mb1360c|M.bovis_AF2122/97 ---------ATLIGNGGNGGNGGVGSAPGKGGAGGTAG-LLGLNGSPGLS
Rv1325c|M.tuberculosis_H37Rv ---------ATLIGNGGNGGNGGVGSAPGKGGAGGTAG-LLGLNGSPGLS
Mflv_5091|M.gilvum_PYR-GCK E--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAA
Mvan_1264|M.vanbaalenii_PYR-1 E--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAA
MSMEG_0868|M.smegmatis_MC2_155 EPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAE
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------HAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGH
MMAR_2097|M.marinum_M -----
MUL_3247|M.ulcerans_Agy99 -----
Mb1360c|M.bovis_AF2122/97 -----
Rv1325c|M.tuberculosis_H37Rv -----
Mflv_5091|M.gilvum_PYR-GCK GDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GDSD-
MSMEG_0868|M.smegmatis_MC2_155 GANNP
TH_3810|M.thermoresistible__bu -----
MAB_4284c|M.abscessus_ATCC_199 HH---
MLBr_01183|M.leprae_Br4923 -----
MAV_4827|M.avium_104 K----