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MSYMFAVPDTVAAAAADLAGIGSTLNAATAAAAAPTTGVLAAGADQVSAAVAALFPGHALDYQALSTQVA AFHTQFVEAVTGAGNAYAAAEAANASPLLGISQDMLNAVNGPTEASLGRPLIGNGADGTAPEQAGGDGSL LYGNGGAGGPGGAGGNAGLIGNGGAGGSGAALGLFGGSGAALGLFGGTGGNGGLLFGDGGTGGAAGDLAS GVGLPGGAGGHAGLFGIGGAGGEGGNSATTAGVGGAGGAGGLLVGAGGHGGTGGTSASGTGATGGSGGAG GLLFSPGGAGGDGGAGFSGADGGAGGNGGAGGGGLWFGNGGAGGIGGFDAHGDGGDGGAGGNAGIYGGNG GAGGTGGVGVGGNLFTGGQGGAGGNAGLLAGNGGAGGTGGDAGMFGNGGAGGAGGDRVAGSQGNGGDGGD GGHGGTYFGSGGAGGHGGYDDSGSGGQGGHGGDGGAAGTIGNGGDGGTGGDALVSGGTGGDGGDGGDGGD AREIGNGGNGGNAGAGATAGNEGTGGTGGQLIGVSGTDGST
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_3247 | - | - | 100% (531) | PE-PGRS family protein |
M. ulcerans Agy99 | MUL_3292 | - | e-146 | 51.20% (623) | PE-PGRS family protein |
M. ulcerans Agy99 | MUL_0212 | - | e-140 | 47.30% (649) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1849c | PE_PGRS33 | 1e-155 | 57.22% (540) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 4e-95 | 44.99% (529) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv1818c | PE_PGRS33 | 1e-154 | 57.04% (540) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 2e-11 | 36.46% (96) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 1e-42 | 35.12% (430) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_2097 | - | 0.0 | 84.05% (608) | PE-PGRS family protein, PE_PGRS33 |
M. avium 104 | MAV_4827 | - | 1e-23 | 46.58% (161) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-79 | 36.93% (612) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 3e-41 | 44.59% (296) | PUTATIVE - |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 7e-95 | 47.82% (481) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment MUL_3247|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2097|M.marinum_M -------------------------------------------------- Mb1849c|M.bovis_AF2122/97 -------------------------------------------------- Rv1818c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3247|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2097|M.marinum_M -------------------------------------------------- Mb1849c|M.bovis_AF2122/97 -------------------------------------------------- Rv1818c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3247|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2097|M.marinum_M -------------------------------------------------- Mb1849c|M.bovis_AF2122/97 -------------------------------------------------- Rv1818c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3247|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2097|M.marinum_M -------------------------------------------------- Mb1849c|M.bovis_AF2122/97 -------------------------------------------------- Rv1818c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3247|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2097|M.marinum_M -------------------------------------------------- Mb1849c|M.bovis_AF2122/97 -------------------------------------------------- Rv1818c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 EAA-------------------------------------LANAGLSAVS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS MUL_3247|M.ulcerans_Agy99 -------MSYMFAVPDTVAAAAADLAGIGSTLNAATAAAAAPTTGVLAAG MMAR_2097|M.marinum_M -------MSYMFAVPDTVAAAAADLAGIGSTLNAATAAAAAPTTGVLAAG Mb1849c|M.bovis_AF2122/97 -------MSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLAAA Rv1818c|M.tuberculosis_H37Rv -------MSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLAAA Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG TH_3810|M.thermoresistible__bu ------------------------------------------------VD MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ MLBr_01183|M.leprae_Br4923 -------------------------------------------MPLFLNA MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT MUL_3247|M.ulcerans_Agy99 ADQVSAAVAALFPGHALDYQALSTQVAAFHTQFVEAVTGAGNAYAAAEAA MMAR_2097|M.marinum_M ADQVSAAVAALFSGHALDYQALSTQVAAFHTQFVEAVTGAGNAYAAAEAA Mb1849c|M.bovis_AF2122/97 ADEVSAAMAALFSGHAQAYQALSAQAALFHEQFVRALTAGAGSYAAAEAA Rv1818c|M.tuberculosis_H37Rv ADEVSAAMAALFSGHAQAYQALSAQAALFHEQFVRALTAGAGSYAAAEAA Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN MLBr_01183|M.leprae_Br4923 EPQALTAAANTLEGLSAATVASNAAAAQLTTEIAP------PAADDVSIL MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA . MUL_3247|M.ulcerans_Agy99 NASPLLGISQDMLNAVNGPTEASLGRPLIGNGADGT-------------- MMAR_2097|M.marinum_M NASPLLGISQDMLNAVNGPTEALLGRPLIGNGADGT-------------- Mb1849c|M.bovis_AF2122/97 SAAPLEGV----LDVINAPALALLGRPLIGNGANGAP------------- Rv1818c|M.tuberculosis_H37Rv SAAPLEGV----LDVINAPALALLGRPLIGNGANGAP------------- Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG--------------- MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSG--------------- MLBr_01183|M.leprae_Br4923 LAHFFSG----------------HGRQYQAHASQG--------------- MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP------------- . . MUL_3247|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2097|M.marinum_M -------------------------------------------------- Mb1849c|M.bovis_AF2122/97 -------------------------------------------------- Rv1818c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------ Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------ MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3247|M.ulcerans_Agy99 -------APEQAGGDGSLLYGNGGAGG---------------PGGAGGNA MMAR_2097|M.marinum_M -------APGQAGGDGGLLYGNGGAGG---------------PGGAGGNA Mb1849c|M.bovis_AF2122/97 -------GTGANGGDGGILIGNGGAGGS---------GAAGMPGGNGGAA Rv1818c|M.tuberculosis_H37Rv -------GTGANGGDGGILIGNGGAGGS---------GAAGMPGGNGGAA Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS TH_3810|M.thermoresistible__bu --------NGYRTTDNNALDGGHGGNG-----------------GNVGFF MAB_4284c|M.abscessus_ATCC_199 --------PIASGQGSTAVNGDVRDSN-----IINADHGSNVGVDQSQTR MLBr_01183|M.leprae_Br4923 -------ATNHQDLIQSLLTSSSAYAG----------------TETANHD MAV_4827|M.avium_104 --------DVYKQQIRAESYGDAAGQLS--------AMVAGLEKLESLPG .. MUL_3247|M.ulcerans_Agy99 GLIGNG-----------------------------GAGGSG--------- MMAR_2097|M.marinum_M GLIGNG-----------------------------GAGGSG--------- Mb1849c|M.bovis_AF2122/97 GLFGNG-----------------------------GAGGAGGNVA----- Rv1818c|M.tuberculosis_H37Rv GLFGNG-----------------------------GAGGAGGNVA----- Mflv_5091|M.gilvum_PYR-GCK ETGTTG---GAGGVG--------------------GQGTAGGTGGVGGIG Mvan_1264|M.vanbaalenii_PYR-1 ETGVTG---GVGGIG--------------------GQGTEGGTGGVGGVG MSMEG_0868|M.smegmatis_MC2_155 TGTGIG---GNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMG TH_3810|M.thermoresistible__bu SLFNLG---GAGGWG--------------------GSGVDG--------- MAB_4284c|M.abscessus_ATCC_199 VGGDYTNVSGHG-----------------------SADIDKSVTVVDDHS MLBr_01183|M.leprae_Br4923 SL------------------------------------------------ MAV_4827|M.avium_104 GLLLVG----------------------------SGVDVAPLKQVLQTTT MUL_3247|M.ulcerans_Agy99 ------------AALGLFGGSG---------------------------- MMAR_2097|M.marinum_M ------------AALGLFGG------------------------------ Mb1849c|M.bovis_AF2122/97 ------------SGTAGFGG------------------------------ Rv1818c|M.tuberculosis_H37Rv ------------SGTAGFGG------------------------------ Mflv_5091|M.gilvum_PYR-GCK GAG----------STGAVGG-------VGGKG----IQGGQG-------- Mvan_1264|M.vanbaalenii_PYR-1 GVG----------ATGGAGG-------VGGKG----IQGGQG-------- MSMEG_0868|M.smegmatis_MC2_155 EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKAS TH_3810|M.thermoresistible__bu --------------VDVVGG------------------------------ MAB_4284c|M.abscessus_ATCC_199 QRN----------TTNINDS------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 FLD-----------VSVAEE------------------------------ MUL_3247|M.ulcerans_Agy99 ----AALGLFGGTGGNGG-----------------------------LLF MMAR_2097|M.marinum_M ------------TGGNGG-----------------------------LLF Mb1849c|M.bovis_AF2122/97 ------------AGGAGG-----------------------------LLY Rv1818c|M.tuberculosis_H37Rv ------------AGGAGG-----------------------------LLY Mflv_5091|M.gilvum_PYR-GCK -----LQGGKGGDGGAGGKGGDADSMGS------------------AGAT Mvan_1264|M.vanbaalenii_PYR-1 -----LQGGQGGDGGTGGTGGDATSMGE------------------AGAT MSMEG_0868|M.smegmatis_MC2_155 GTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASAN TH_3810|M.thermoresistible__bu ----------NPDGGTPG------------------------------AH MAB_4284c|M.abscessus_ATCC_199 -----FNTDRSTNIGSGNTTNTEIGSHN------------------QANI MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------PETALARG-----------------------------AAL MUL_3247|M.ulcerans_Agy99 GDGGTGGAAGDLASGVG--------------------------------- MMAR_2097|M.marinum_M GNGGTGGAAGDLASGVG--------------------------------- Mb1849c|M.bovis_AF2122/97 GAGGAGGAGGRAGGGVG--------------------------------- Rv1818c|M.tuberculosis_H37Rv GAGGAGGAGGRAGGGVG--------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-------- Mvan_1264|M.vanbaalenii_PYR-1 GGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-------- MSMEG_0868|M.smegmatis_MC2_155 GAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP TH_3810|M.thermoresistible__bu GESHTPGVYTDRQ------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GTSTSAGGSAAVGGNAG--------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AAANAPLFASSTAALAYAQ------------------------------- MUL_3247|M.ulcerans_Agy99 ---------------LPGGAGGHAG----LFGIGGAGG------------ MMAR_2097|M.marinum_M ---------------LPGGAGGHAG----LFGIGGAGG------------ Mb1849c|M.bovis_AF2122/97 ---------------GIGGAGGAGGNGGLLFGAGGAGS------------ Rv1818c|M.tuberculosis_H37Rv ---------------GIGGAGGAGGNGGLLFGAGGAGG------------ Mflv_5091|M.gilvum_PYR-GCK --------------GGTGGAGGAGGTGG-TGGAGGTGG------------ Mvan_1264|M.vanbaalenii_PYR-1 --------------GGTGGNGGNGGTGG-TGGNGGTGG------------ MSMEG_0868|M.smegmatis_MC2_155 NGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHS TH_3810|M.thermoresistible__bu ------------------GEDGEDGTGTGIGGRGGNGG------------ MAB_4284c|M.abscessus_ATCC_199 ----------------LAGNAGLAGNAGLAGNAGLAGN------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------DPGTGAVDQYSLPDYLYVPVDP------------ MUL_3247|M.ulcerans_Agy99 -----EGGN-----------SATTAGVGGAGGAGGLLVG--AGGHGGTGG MMAR_2097|M.marinum_M -----EGGN-----------SATTAGVGGAGGAGGLLVG--AGGHGGTGG Mb1849c|M.bovis_AF2122/97 -----VGG------------LAADAGDGGAGGDGGLFFG--VGGAGGAGG Rv1818c|M.tuberculosis_H37Rv -----VGG------------LAADAGDGGAGGDGGLFFG--VGGAGGAGG Mflv_5091|M.gilvum_PYR-GCK -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 TGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE--GEGGTGGHGG TH_3810|M.thermoresistible__bu ----SSSGTHPMAEDG--------EHVKALDGRPGLD-----GGNGSHGG MAB_4284c|M.abscessus_ATCC_199 ---AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----EPGDDE--------LAYSAVGEEDAESPTVVIEKLFLPEDSEPRR MUL_3247|M.ulcerans_Agy99 TS-ASGTGATGGSGGAGGLLFSPGGAGGDGGAGFSG---------ADGGA MMAR_2097|M.marinum_M TS-ASGTGATGGSGGAGGLLFSPGGAGGDGGAGFSG---------ADGGA Mb1849c|M.bovis_AF2122/97 TG-TNVTGGAGGAGGNGGLLFGAGGVGGVGGDGVAF---------LGTAP Rv1818c|M.tuberculosis_H37Rv TG-TNVTGGAGGAGGNGGLLFGAGGVGGVGGDGVAF---------LGTAP Mflv_5091|M.gilvum_PYR-GCK TGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGT Mvan_1264|M.vanbaalenii_PYR-1 TGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGT MSMEG_0868|M.smegmatis_MC2_155 DGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGN TH_3810|M.thermoresistible__bu NGGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDAD MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAGLAG----NAGLAGNAGLAGNAG--------LAGNA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 RPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTE MUL_3247|M.ulcerans_Agy99 GGNGGAG------------------------------------------- MMAR_2097|M.marinum_M GGNGGAGGLLFGTGGGGGEGGATSPSSSTGSGGDGGIGGTSGLFGTGGTG Mb1849c|M.bovis_AF2122/97 GGPGGAG------------------------------------------- Rv1818c|M.tuberculosis_H37Rv GGPGGAG------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG----- Mvan_1264|M.vanbaalenii_PYR-1 GGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG----- MSMEG_0868|M.smegmatis_MC2_155 GGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIR TH_3810|M.thermoresistible__bu GGNGGDG---------------GNGGSAG--------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGNAG-------------LAGNAGLAG--------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 QAPAPPP-------------VQASAPQPK--------------------- MUL_3247|M.ulcerans_Agy99 -----------------GGGLWFGNGGAGG-------------------- MMAR_2097|M.marinum_M GAGGAAANATGGNGGAGGGGLWFGNGGAGG-------------------- Mb1849c|M.bovis_AF2122/97 -----------------GAGGLFGVGGAGG-------------------- Rv1818c|M.tuberculosis_H37Rv -----------------GAGGLFGVGGAGG-------------------- Mflv_5091|M.gilvum_PYR-GCK ------------TGGTGGQGG-LGGGGGTG-------------------- Mvan_1264|M.vanbaalenii_PYR-1 ------------TGGTGGQGG-LGGVGGTG-------------------- MSMEG_0868|M.smegmatis_MC2_155 ATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGT TH_3810|M.thermoresistible__bu ------------RGGTGGLRGVFGINGGNG-------------------- MAB_4284c|M.abscessus_ATCC_199 ------------NAAVAGNAAVAGNAAVAG-------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------ISVPEPVAAPKPLSPPVAAP-------------------- MUL_3247|M.ulcerans_Agy99 ----IGGFDAHGDGGDGGAGGNAGIYGG--------------NGGAGGTG MMAR_2097|M.marinum_M ----IGGFDAHGNGGDGGAGGNAGIYGG--------------NGGAGGTG Mb1849c|M.bovis_AF2122/97 ----AGGIGLVGNGGAGGSGGSALLWG---------------DGGAGGAG Rv1818c|M.tuberculosis_H37Rv ----AGGIGLVGNGGAGGSGGSALLWG---------------DGGAGGAG Mflv_5091|M.gilvum_PYR-GCK ---GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLG Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLG MSMEG_0868|M.smegmatis_MC2_155 ATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLG TH_3810|M.thermoresistible__bu ----RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGG MAB_4284c|M.abscessus_ATCC_199 ----NAAVGGVLNTGVSGAIGGSSHVG---------GAINESLGGSGSVG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --LPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPV MUL_3247|M.ulcerans_Agy99 G-VGVGGNLFTGGQGGAGGNAGLLAGNGG--------------------- MMAR_2097|M.marinum_M G-VGVGGNLFTGGQGGAGGNAGLLAGNGG--------------------- Mb1849c|M.bovis_AF2122/97 G-VGS----TTGGAGGAGGNAGLLVGAGG--------------------- Rv1818c|M.tuberculosis_H37Rv G-VGS----TTGGAGGAGGNAGLLVGAGG--------------------- Mflv_5091|M.gilvum_PYR-GCK GFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSG Mvan_1264|M.vanbaalenii_PYR-1 GFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSG MSMEG_0868|M.smegmatis_MC2_155 GNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSG TH_3810|M.thermoresistible__bu GTPSAGFGVPTTIQFPAGSCTSRAVSREG--------------------- MAB_4284c|M.abscessus_ATCC_199 GSTAVGGGAHTGVGGGVSTGVGVGSHVGG--------------------G MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 SPPQLLAPPRLSVPQPVQPPVRVPQPPSP--------------------- MUL_3247|M.ulcerans_Agy99 ----AGG-----------------TGGDAG--------MFGNGGAGGAGG MMAR_2097|M.marinum_M ----AGGNGGVRFSGNAGAGGAGGTGGDAG--------MFGNGGAGGAGG Mb1849c|M.bovis_AF2122/97 ----AGG-------------------------------------AGALGG Rv1818c|M.tuberculosis_H37Rv ----AGG-------------------------------------AGALGG Mflv_5091|M.gilvum_PYR-GCK SAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGK Mvan_1264|M.vanbaalenii_PYR-1 SAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGA MSMEG_0868|M.smegmatis_MC2_155 YGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTAT TH_3810|M.thermoresistible__bu ---IMPSSRAASARAG---------------------------AACASST MAB_4284c|M.abscessus_ATCC_199 ISESLGGSGSVGGSTAVGGGAHTGVGGGVS----------TGVGVGSHVG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --PQVGGTVPQSPPQHQTPPGEGTPPKPDG---------------PGNYG MUL_3247|M.ulcerans_Agy99 DRVAGSQGNGGDGGDGG------------HGGTYFGSGGAGGHGGYDDSG MMAR_2097|M.marinum_M DRVAGSQGNGGDGGDGG------------HGGTYFGSGGAGGHGGYDDSG Mb1849c|M.bovis_AF2122/97 ----GATGVGGAGGNGG------------TAGLLFGAGGAGGAGGF---G Rv1818c|M.tuberculosis_H37Rv ----GATGVGGAGGNGG------------TAGLLFGAG---GAGGF---G Mflv_5091|M.gilvum_PYR-GCK AGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQG Mvan_1264|M.vanbaalenii_PYR-1 QGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQG MSMEG_0868|M.smegmatis_MC2_155 GGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKG TH_3810|M.thermoresistible__bu SRSRRSFCCSRA-------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGISESLGGSGSVGGSTAVG---------GGAHTGVGGGVNTGVGVGSHV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GGHVPTPGAGGSGGSGGG----------HVPTPGAGGSGGSGGGHVPTPG MUL_3247|M.ulcerans_Agy99 SGGQGGHGGDGGAAG--------TIGNGGDGGTGGDALVSGGTGGDGGDG MMAR_2097|M.marinum_M SGGQGGHGGDGGAAG--------TIGNGGDGGTGGDALVSGGTGGDGGDG Mb1849c|M.bovis_AF2122/97 FGGAGGAGGLGGKAG--------LIGDGGDGGAGGNG--TGAKGGDGGAG Rv1818c|M.tuberculosis_H37Rv FGGAGGAGGLGGKAG--------LIGDGGDGGAGGNG--TGAKGGDGGAG Mflv_5091|M.gilvum_PYR-GCK AAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-- Mvan_1264|M.vanbaalenii_PYR-1 AAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-- MSMEG_0868|M.smegmatis_MC2_155 ADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVG-------GSTAVGGGAHTSAINDALGGSGSVGG-- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 TGGPGGTGGSGGGHVP-------TPGAGTPGGSGGGHLPFPGAGSTPGGS MUL_3247|M.ulcerans_Agy99 G--------DGGDAREIGNGGNGG-------------NAGAGATAGNEGT MMAR_2097|M.marinum_M -----------GDAREIGNGGNGG-------------NAGAGATAGNEGT Mb1849c|M.bovis_AF2122/97 -----------GGAILVGNGGNGG-------------NAGSGTPNGSAGT Rv1818c|M.tuberculosis_H37Rv -----------GGAILVGNGGNGG-------------NAGSGTPNGSAGT Mflv_5091|M.gilvum_PYR-GCK ---------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGA Mvan_1264|M.vanbaalenii_PYR-1 ---------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGT MSMEG_0868|M.smegmatis_MC2_155 SVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------GGGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLGGGGGHAPA MUL_3247|M.ulcerans_Agy99 GGTGGQLIGVSGTDGST--------------- MMAR_2097|M.marinum_M GGTGGQLIGVSGTDGST--------------- Mb1849c|M.bovis_AF2122/97 GGAGG-LLGKNGMNGLP--------------- Rv1818c|M.tuberculosis_H37Rv GGAGG-LLGKNGMNGLP--------------- Mflv_5091|M.gilvum_PYR-GCK GGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 GGAG--GAGGSGGSGGSGGAGGSGGAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 GGSGNGGNGGNGGNGGADGTPGTAGTTGANNP TH_3810|M.thermoresistible__bu -------------------------------- MAB_4284c|M.abscessus_ATCC_199 AGTGFEAQGHAQGHASETAHTTLPGAEHH--- MLBr_01183|M.leprae_Br4923 -------------------------------- MAV_4827|M.avium_104 PGGGLGGFGGGHSGGGLGGLGGGHK-------