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TTVEQARPSAALETPAPQARWIRPAYWAMLVGTAVLYLWGLGSKGWANSYYAAAAQAATQSWKAWLFGSL DAGNAITVDKPPAAMWAMGLSGRLFGFNEFTMLLPEALMGVAAVAVLYATVRRTSGPVAGLVAGTALALT PVATVMFRYNNPDALLVLLLVVAAYFMVRAIGASGARAATGWVVLCGCALGFAFLTKMLQAFLIVPGLAL AFLVAAPVASVAKRVGILLAGGVAMAVSAGWYLALVALWPAGSRPYIAGSTDNSLLQLAFGYNGIERIVG RGGGPGFGGGPGPGGGGPGPGGGGSRGIFHSGDPGIGRLFNDALGTEVAWLLPVALIGLVVLLWLTRHTV RTSATRAGLLVWGGWLAVTGVVFSFMDGTIHPYYTVALAPAVAALAGISVVELWRRRSHVGIRLLLAAMM GLTGVWAFVLLNRTPDWWPALRWVVLIGSVVVAVLLALRAHRPGQVTAALALAAVVLGLGSTLAYSVETV ANGQSGGPLPMAGPQRGGGFGFGGPHRGERDDDTALRELISDTDNRWAAASVGSWMVSDLELKTGESLMA IGGFMGADDSPTLEQFQQYVERGDVRYFLAPAEGRRGPGGFRHGSAGDITNWVKENFPKTEVGGVTVYDL QSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4986 | - | - | 100% (634) | glycosyl transferase, family protein 39 |
| M. smegmatis MC2 155 | MSMEG_4988 | - | e-143 | 46.04% (632) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_0627 | - | e-116 | 40.38% (624) | glycosyl transferase, family protein 39 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1029c | - | 4e-06 | 27.40% (281) | hypothetical protein Mb1029c |
| M. gilvum PYR-GCK | Mflv_2269 | - | 0.0 | 64.88% (635) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv1002c | - | 3e-06 | 27.40% (281) | hypothetical protein Rv1002c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0927 | - | 1e-144 | 46.02% (628) | glycosyltransferase |
| M. marinum M | MMAR_4491 | - | 1e-05 | 28.46% (253) | hypothetical protein MMAR_4491 |
| M. avium 104 | MAV_2780 | - | 3e-05 | 80.00% (25) | hypothetical protein MAV_2780 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0572 | - | 4e-05 | 36.04% (111) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_4425 | - | 0.0 | 64.88% (635) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1029c|M.bovis_AF2122/97 --------------------------------------------------
Rv1002c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4491|M.marinum_M --------------------------------------------------
Mflv_2269|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4425|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4986|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0927|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 MSYVVAIPDMLASAAADVAGIGSSVGAANTAAVGATTGVMAAADDEVSVA
Mb1029c|M.bovis_AF2122/97 -------------------------------------MVPVVSPGPLVPV
Rv1002c|M.tuberculosis_H37Rv -------------------------------------MVPVVSPGPLVPV
MMAR_4491|M.marinum_M ----------------------MTAPPQETSVVAGERAVPVVSPGPLVPI
Mflv_2269|M.gilvum_PYR-GCK -------------------------------------MTTTVRTGVRSAP
Mvan_4425|M.vanbaalenii_PYR-1 -------------------------------------MTATADLAPRTTA
MSMEG_4986|M.smegmatis_MC2_155 --------------------------------------MTTVEQARPSAA
MAB_0927|M.abscessus_ATCC_1997 --------------------------------------MSVLSTARGRAR
MAV_2780|M.avium_104 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 IAALFSGHGQAYQAISAQAAAFHDQFLRALTGAGGAYAAAEAANASPLQA
Mb1029c|M.bovis_AF2122/97 ADFGPLDRLRGWIVTGLITLLA--TVTRFLNLGSLTDAG-----TPIFDE
Rv1002c|M.tuberculosis_H37Rv ADFGPLDRLRGWIVTGLITLLA--TVTRFLNLGSLTDAG-----TPIFDE
MMAR_4491|M.marinum_M ADFGPVDRLRGWVVTGVITLLA--AVTRFLNLGSPTDAG-----TPIFDE
Mflv_2269|M.gilvum_PYR-GCK --HPEADTRPRWVTPALLALLASTAVLYLWGLGSSGWAN-----QYYAAA
Mvan_4425|M.vanbaalenii_PYR-1 DAEPVATERPRWMWPALLALLGATAVLYLWGLGSAGWAN-----QYYAAA
MSMEG_4986|M.smegmatis_MC2_155 LETPAPQAR--WIRPAYWAMLVGTAVLYLWGLGSKGWAN-----SYYAAA
MAB_0927|M.abscessus_ATCC_1997 ------------EPLSVTLLLVGTAVAYLINLASNGWAN-----SFYSAA
MAV_2780|M.avium_104 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 AEQEVLAVINAPTNALLGRPLIGNGTDGLAGTGAAGGAGGLLWGNGGNGG
Mb1029c|M.bovis_AF2122/97 KHYAPQAWQVLNNHGVEDNPGYGLVVHP----------------------
Rv1002c|M.tuberculosis_H37Rv KHYAPQAWQVLNNHGVEDNPGYGLVVHP----------------------
MMAR_4491|M.marinum_M KHYAPQAWQVLNNHGIEDNPGFGLVVHP----------------------
Mflv_2269|M.gilvum_PYR-GCK AQAGTQDWKAW-LFGSLDAGNAITVDKP----------------------
Mvan_4425|M.vanbaalenii_PYR-1 AQAGTQDWKAW-LFGSLDAGNAITVDKP----------------------
MSMEG_4986|M.smegmatis_MC2_155 AQAATQSWKAW-LFGSLDAGNAITVDKP----------------------
MAB_0927|M.abscessus_ATCC_1997 VQAGSVSWKAG-FFGSSDAANSITVDKP----------------------
MAV_2780|M.avium_104 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 SGAAGQAGGAGGAAGLIGTGGAGGMGGAGGGAGGMGGSGGWLLGNGGAGG
Mb1029c|M.bovis_AF2122/97 PVGKQLIAIGEAIFGYNGFGWRFTGALLG---VLLVALVVRIVRRISRST
Rv1002c|M.tuberculosis_H37Rv PVGKQLIAIGEAIFGYNGFGWRFTGALLG---VVLVALVVRIVRRISRST
MMAR_4491|M.marinum_M PVGKQMIAIGEALFGYTGLGWRFSGALLG---VVMVALVVRIVRRITRST
Mflv_2269|M.gilvum_PYR-GCK PASLWVMALSGRVFGFSPFTMLLPQALMG---VASVAVLVAAVRRLS-GP
Mvan_4425|M.vanbaalenii_PYR-1 PAALWVMALSGRLFGFSPFTMLLPQALMG---VASVAVLFAAVRRVS-GP
MSMEG_4986|M.smegmatis_MC2_155 PAAMWAMGLSGRLFGFNEFTMLLPEALMG---VAAVAVLYATVRRTS-GP
MAB_0927|M.abscessus_ATCC_1997 PAALWLMELSVRVFGLSGWSILVPQVLLG---VASVGLLYATVRRYF-GH
MAV_2780|M.avium_104 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 AGGVGCAGVSGGVGGTGGNAMLFGNGGAGGMGGAGADGAVGAAGTAGTST
Mb1029c|M.bovis_AF2122/97 LVGAIAGVLLICDGVSFVTARTAL--------------------------
Rv1002c|M.tuberculosis_H37Rv LVGAIAGVLLICDGVSFVTARTAL--------------------------
MMAR_4491|M.marinum_M LVGAIAGLLLICDGVSFVAARTAL--------------------------
Mflv_2269|M.gilvum_PYR-GCK GAGLIAGAALAVTPVAALMFRYNN--------------------------
Mvan_4425|M.vanbaalenii_PYR-1 GAGLIAGAALAVTPVAALMFRYNN--------------------------
MSMEG_4986|M.smegmatis_MC2_155 VAGLVAGTALALTPVATVMFRYNN--------------------------
MAB_0927|M.abscessus_ATCC_1997 RAGLLAGLVLAVTPVAVLMFRFNN--------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 SAGGVGGAGWDATAAGVLAATGGDGGDSGGGGAGGNGGAGGAGGHGSALF
Mb1029c|M.bovis_AF2122/97 -LDGFLTFFVVAAFGALIVDRDQVRER------------MHIALLAGRSA
Rv1002c|M.tuberculosis_H37Rv -LDGFLTFFVVAAFGALIVDRDQVRER------------MHIALLAGRSA
MMAR_4491|M.marinum_M -LDGFLTFFVVAAFGALIVDRDQVRAR------------MHVAMLQGRIG
Mflv_2269|M.gilvum_PYR-GCK -PDALLVLLLVVAAYLMVRAIQTGGTR----WVVLVGVVLGVAFLTKMLQ
Mvan_4425|M.vanbaalenii_PYR-1 -PDALLVLLLVVAAYLTVRAIQTGGTR----WMVLVGIVLGFAFLTKMLQ
MSMEG_4986|M.smegmatis_MC2_155 -PDALLVLLLVVAAYFMVRAIGASGARAATGWVVLCGCALGFAFLTKMLQ
MAB_0927|M.abscessus_ATCC_1997 -PDALLVFLMIAAVWAMMRAVEDGRTR----WMLLVGVFVGFGFLTKQLQ
MAV_2780|M.avium_104 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 GADGANGNGGAGGAGGNPGAPGNGGTGGVGPDAATSGGMGGTGGDPGAVG
Mb1029c|M.bovis_AF2122/97 ATVWGPRVGVRWWRFG--------AGVLLGLACATKWSGVYFVLFFG---
Rv1002c|M.tuberculosis_H37Rv ATVWGPRVGVRWWRFG--------AGVLLGLACATKWSGVYFVLFFG---
MMAR_4491|M.marinum_M ETAWGPRLGVRWWRFG--------AGVLLGLAFATKWSGLYFIAFFG---
Mflv_2269|M.gilvum_PYR-GCK AFLVVPGLALAFLVAAPVG-VWARVGKLAAGGVAMIATAGSFLTLVSVWP
Mvan_4425|M.vanbaalenii_PYR-1 AFLVMPGLALAFLVAAPVG-LWRRIGTLLTGALAMVATAGSFLAMVSLWP
MSMEG_4986|M.smegmatis_MC2_155 AFLIVPGLALAFLVAAPVASVAKRVGILLAGGVAMAVSAGWYLALVALWP
MAB_0927|M.abscessus_ATCC_1997 VLLVIPPVAVTYLIAGPAG-AGKRLAQLVGSAAAAVVSAGWWIAAVELWP
MAV_2780|M.avium_104 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 GRGNSGAAGGAGAVAGASG---AAGTIIAGNGGNGGAGGAGYAADGPAGP
Mb1029c|M.bovis_AF2122/97 ----------------AMALAFDVAARRQYQVQRP---------------
Rv1002c|M.tuberculosis_H37Rv ----------------AMALAFDVAARRQYQVQRP---------------
MMAR_4491|M.marinum_M ----------------AMSLAFDVAARRQYRVPRP---------------
Mflv_2269|M.gilvum_PYR-GCK ADARPYIGGSTDNSLLQLALGYNGIQRVMGGQGGP--GGPPGGGLGGPPA
Mvan_4425|M.vanbaalenii_PYR-1 ADSRPYIGGSTDNSLLQLALGYNGIQRVMGGEGGP--GGGAG-----APP
MSMEG_4986|M.smegmatis_MC2_155 AGSRPYIAGSTDNSLLQLAFGYNGIERIVGRGGGPGFGGGPG-----PGG
MAB_0927|M.abscessus_ATCC_1997 PGSRPWIGGSPDNSILELTLGYNGLGRINGNETGS----ASG-----PRE
MAV_2780|M.avium_104 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 AIGNGGDGGHGGAGGFYGNGGAGGAGGNSAPGGGTGGNGGTGGDSGAMGS
Mb1029c|M.bovis_AF2122/97 --------------------------------------------------
Rv1002c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4491|M.marinum_M --------------------------------------------------
Mflv_2269|M.gilvum_PYR-GCK GGPGGPGGGAN-------------------------LFFGGEPDIGRLFG
Mvan_4425|M.vanbaalenii_PYR-1 GGPGGPGGGAN-------------------------LFFGGDPGLGRLFG
MSMEG_4986|M.smegmatis_MC2_155 GGPGPGGGGSRG------------------------IFHSGDPGIGRLFN
MAB_0927|M.abscessus_ATCC_1997 GMYGFGG------------------------------HFGSEPGIGRLFQ
MAV_2780|M.avium_104 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 SGGRGGDGGVGTNGGAGGGGGNATSYGTANATGGAGGDGGTGSTGNGGSG
Mb1029c|M.bovis_AF2122/97 --------WLG------------TVRRDVLPSGYALGLIPFAVYLATYAP
Rv1002c|M.tuberculosis_H37Rv --------WLG------------TVRRDVLPSGYALGLIPFAVYLATYAP
MMAR_4491|M.marinum_M --------WLG------------MLRRDLIPTGYALALIPFGVYLASYAG
Mflv_2269|M.gilvum_PYR-GCK ASMGAEASWLLPAALIGLVAALWITRRAARTDAIRAGLLLWGGWVLVTGV
Mvan_4425|M.vanbaalenii_PYR-1 ASMGAEASWLLPAALIGLVAGLWFTRRAPRTCAVRASLLLWGGWVLVTGV
MSMEG_4986|M.smegmatis_MC2_155 DALGTEVAWLLPVALIGLVVLLWLTRHTVRTSATRAGLLVWGGWLAVTGV
MAB_0927|M.abscessus_ATCC_1997 PALGGQIAWLLPTALLLAILGIVLLRNNSRTDARRAVLIVFGLWILTTGI
MAV_2780|M.avium_104 ---------------------------MFGGAA----MLVL---------
MUL_0572|M.ulcerans_Agy99 GDGGNGGTGHGGGGGPGGTAINYGAGDAFGGAAGKGGTGVVGGNGGSGGA
.
Mb1029c|M.bovis_AF2122/97 WFASETAIDRHAVGQAVGRNSVVPLPDAVRSLWHYTAKAFH---------
Rv1002c|M.tuberculosis_H37Rv WFASETAIDRHAVGQAVGRNSVVPLPDAVRSLWHYTAKAFH---------
MMAR_4491|M.marinum_M WFASETAIDRHQVGLTIGPDSVVPLPDAIRSLWYYTAKAFH---------
Mflv_2269|M.gilvum_PYR-GCK VFSYMDGIIHPYYTVALAPGIAALIGISVVTLWRGRGLFAPRLILAAMSA
Mvan_4425|M.vanbaalenii_PYR-1 VFSFMDGIIHPYYTVALAPGIAALIGICVVELWRGRRHFAPRTTLAVMSA
MSMEG_4986|M.smegmatis_MC2_155 VFSFMDGTIHPYYTVALAPAVAALAGISVVELWRRRSHVGIRLLLAAMMG
MAB_0927|M.abscessus_ATCC_1997 VFSYMQGIFHPYYSMALTPAVAALVGAGSVLGWREREKSWVRACLAALLM
MAV_2780|M.avium_104 --------AVGCGGGHKGG-----PSTTSTTTPTT---------------
MUL_0572|M.ulcerans_Agy99 AYNYGTGNATGAGGSSGSGGAASVPNSASTATATSGSGGAGGDGTDGGNG
Mb1029c|M.bovis_AF2122/97 ----FHAGLTNSAGNYHPWESKPWTWP------------------MSLRP
Rv1002c|M.tuberculosis_H37Rv ----FHAGLTNSAGNYHPWESKPWTWP------------------MSLRP
MMAR_4491|M.marinum_M ----FHATLTNSAGNHHPWESKPWSWP------------------MSLRP
Mflv_2269|M.gilvum_PYR-GCK VTGVWAFVLLDRTPEWQPWLRWVVLVG------------------SIAVA
Mvan_4425|M.vanbaalenii_PYR-1 GTGVWAFILLDRTPDWQPWLRWVVLIG------------------SIVAA
MSMEG_4986|M.smegmatis_MC2_155 LTGVWAFVLLNRTPDWWPALRWVVLIG------------------SVVVA
MAB_0927|M.abscessus_ATCC_1997 LTAAMAWLLLGRSPEFQPWLRWAILIL------------------ALLAL
MAV_2780|M.avium_104 -----------------------TPST-------------------SVVP
MUL_0572|M.ulcerans_Agy99 GSGGFAFTFGTGNIIAGVGGGGGTGSTGVGGIGGSGGGADINNGAFTVVP
Mb1029c|M.bovis_AF2122/97 VLYAIDQQDVAGCGAQSCVKAEML-VGTPAMWWLAVPVLAYAGWRMFVRR
Rv1002c|M.tuberculosis_H37Rv VLYAIDQQDVAGCGAQSCVKAEML-VGTPAMWWLAVPVLAYAGWRMFVRR
MMAR_4491|M.marinum_M VLYAIDQQNVPGCGPQSCVKAEML-VGTPAMWWLAVPVLLYAAWRMFVRR
Mflv_2269|M.gilvum_PYR-GCK VVFSAGAHRLGRATVAVAAAAIVLGAAAPLAYALETALHSHAGGAMAMSG
Mvan_4425|M.vanbaalenii_PYR-1 AVIAVGAHRLGRATAAVAAAAILFGAAAPAAYAIETAGNAHDG-PVAMSG
MSMEG_4986|M.smegmatis_MC2_155 VLLALRAHRPGQVTAALALAAVVLGLGSTLAYSVETVANGQSGGPLPMAG
MAB_0927|M.abscessus_ATCC_1997 IGLAMS-----RCPKAVVVAALVAALAGPVAYSAATIATPHGG-ALPSAG
MAV_2780|M.avium_104 ----------STTPGGGG---------------TVPGGPTGGGGPGGGG-
MUL_0572|M.ulcerans_Agy99 QGGAGGHGGDGATDGGAGGAGGFTEIDSSASVIAATGGAGGDGGSGGTGR
.
Mb1029c|M.bovis_AF2122/97 DWRYAVVLVGYCAG---------------WLPWFADIDR-----------
Rv1002c|M.tuberculosis_H37Rv DWRYAVVLVGYCAG---------------WLPWFADIDR-----------
MMAR_4491|M.marinum_M DWRYAAVLVGYCAG---------------WLPWFADIDR-----------
Mflv_2269|M.gilvum_PYR-GCK PAR-DSGFG-GPGGPAGPDG---DNTELQ--ELVRSADN-----------
Mvan_4425|M.vanbaalenii_PYR-1 PARTDVDLG-GPPGPGGPGASVADNTELQ--HLVQATDS-----------
MSMEG_4986|M.smegmatis_MC2_155 PQR-GGGFG-FGGPHRGERD---DDTALR--ELISDTDN-----------
MAB_0927|M.abscessus_ATCC_1997 PEVNGGGFPEFPDMPERPHRAEFEPASKRGGSLLDGSDPGP---------
MAV_2780|M.avium_104 GSIPGGPTGGGGPGGGGGS---------IPGGP-----------------
MUL_0572|M.ulcerans_Agy99 GGTGGGGTGGGGTGGGGGVGINNGSGEAIGGAPGAGGTGAVGGDGGQGGA
Mb1029c|M.bovis_AF2122/97 -----------------QMYFFYAATMAPFLVMGISLVLGDILYHPG-QG
Rv1002c|M.tuberculosis_H37Rv -----------------QMYFFYAATMAPFLVMGISLVLGDILYHPG-QG
MMAR_4491|M.marinum_M -----------------QMYFFYAATMAPFLVMAIALILGDILHQPG-QG
Mflv_2269|M.gilvum_PYR-GCK --------------------RWAAAGVGSMLTGDLQLRTGASVMAIGGFT
Mvan_4425|M.vanbaalenii_PYR-1 --------------------RWAAASVGSMVAGELELQTGTSVMAIGGFT
MSMEG_4986|M.smegmatis_MC2_155 --------------------RWAAASVGSWMVSDLELKTGESLMAIGGFM
MAB_0927|M.abscessus_ATCC_1997 -------NIVAALNDNADRYTWVAAAIGSNQASGYQLATRRPVMPIGGFN
MAV_2780|M.avium_104 ---------------------TGGGGPGGGG---------------GSIP
MUL_0572|M.ulcerans_Agy99 AYSYGTGDATGSAGAAGTAGTTGVGGTGGAGGAAYTLNGASTATATGGIG
. . *
Mb1029c|M.bovis_AF2122/97 SERRTLGLIVVCCYVALVVTNFAWLY-----------PVLTGLPISQQTW
Rv1002c|M.tuberculosis_H37Rv SERRTLGLIVVCCYVALVVTNFAWLY-----------PVLTGLPISQQTW
MMAR_4491|M.marinum_M KERHTLGLIFVCCYIALVATNFAWLF-----------PVLTGLPISQQTW
Mflv_2269|M.gilvum_PYR-GCK GGDNAPTLEQFQQYVADGQVRYFIAG---GHG--GPGGG-ARSASQITAW
Mvan_4425|M.vanbaalenii_PYR-1 GGDNSPTLQQFQDYVADRQVRYFIAG---GHG--GPGRN-SGSAGDITAW
MSMEG_4986|M.smegmatis_MC2_155 GADDSPTLEQFQQYVERGDVRYFLAP---AEGRRGPGGFRHGSAGDITNW
MAB_0927|M.abscessus_ATCC_1997 GTDPSPTLAQFQQYVADGQIHYFIDGERGSHGDEGFGPPGSETSKSIREW
MAV_2780|M.avium_104 GVGGGG-------GGPGGGGG----------CVGN---------------
MUL_0572|M.ulcerans_Agy99 GNGGDGGTANGSNGGNGGAGGYASTTGTGTASVGNGGRGGDGTATVATGG
Mb1029c|M.bovis_AF2122/97 NLEIWLPSWR--------------------------------
Rv1002c|M.tuberculosis_H37Rv NLEIWLPSWR--------------------------------
MMAR_4491|M.marinum_M DMQMWLPSWR--------------------------------
Mflv_2269|M.gilvum_PYR-GCK VTQTFAPRDVGGTAVYDLQR----------------------
Mvan_4425|M.vanbaalenii_PYR-1 VEQNFAPMDVGGTTVYDLQR----------------------
MSMEG_4986|M.smegmatis_MC2_155 VKENFPKTEVGGVTVYDLQSR---------------------
MAB_0927|M.abscessus_ATCC_1997 VQRTFTKKTIDDVEVYDLTGH---------------------
MAV_2780|M.avium_104 ---VCG-AYP--------------------------------
MUL_0572|M.ulcerans_Agy99 TGGVGGNAHAPAGSPVPGVGGKGGNPGPGGKPGPNGADGIVV