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HMIAVVMTPVVSLATVVAVAAPAAADCTTAGATTICSQGDVRGTNSGTGPVGSSGPYVPYPCDWNYYNCN EWWDVDFDVDLDPGRPGIGGPGGPGGPGIGAPGGPGRPGGGFGGGGGRGGGGRR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_4805 | - | - | 100% (125) | hypothetical protein Mflv_4805 |
M. gilvum PYR-GCK | Mflv_4039 | infB | 7e-08 | 63.04% (46) | translation initiation factor IF-2 |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-07 | 36.21% (116) | triple helix repeat-containing collagen |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1485c | PE_PGRS27 | 2e-09 | 69.23% (39) | PE-PGRS family protein |
M. tuberculosis H37Rv | Rv3512 | PE_PGRS56 | 2e-08 | 36.27% (102) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 1e-05 | 50.00% (52) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_1609c | - | 3e-18 | 44.44% (117) | hypothetical protein MAB_1609c |
M. marinum M | MMAR_3811 | - | 7e-10 | 74.29% (35) | hypothetical protein MMAR_3811 |
M. avium 104 | MAV_3693 | infB | 3e-08 | 60.47% (43) | translation initiation factor IF-2 |
M. smegmatis MC2 155 | MSMEG_5499 | - | 4e-17 | 40.00% (115) | hypothetical protein MSMEG_5499 |
M. thermoresistible (build 8) | TH_3810 | - | 1e-05 | 34.29% (105) | PUTATIVE - |
M. ulcerans Agy99 | MUL_3062 | - | 6e-08 | 61.54% (39) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1637 | - | 3e-42 | 64.46% (121) | hypothetical protein Mvan_1637 |
CLUSTAL 2.0.9 multiple sequence alignment Mb1485c|M.bovis_AF2122/97 MSLVIVAPETVAAAALDVARIGSSIGVANSAAAGSTTSVLAAGADEVSAA MUL_3062|M.ulcerans_Agy99 MAFVLAVPDMVAEAAADLAGVGSVIDAANTAAAGSTTGIVAAAEDEVSAA Rv3512|M.tuberculosis_H37Rv -----------PQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAG TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK ------------------------------------------MH-----M Mvan_1637|M.vanbaalenii_PYR-1 ------------------------------------------MR-----L MAB_1609c|M.abscessus_ATCC_199 ------------------------------------------MRTMRCYL MSMEG_5499|M.smegmatis_MC2_155 ------------------------------------------MRSTQRYL MLBr_01556|M.leprae_Br4923 ---------------------------------MAGKARVHELAKELGVT MAV_3693|M.avium_104 ---------------------------------MAGKARVHELAKELGVT Mb1485c|M.bovis_AF2122/97 IATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSYVS-----AEATNA MUL_3062|M.ulcerans_Agy99 IAALFSGHGQAYQQISTRVAEFHAQFERVFAAGVQAYSG-----AEAANA Rv3512|M.tuberculosis_H37Rv GAGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGDGALAGSS TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK IAVVMTPVVSLATVVAVAAPAAADCTT-----------------AGATTI Mvan_1637|M.vanbaalenii_PYR-1 VYLIAVPVV-VSTGIAIAPPAVADCTS-----------------AGGTTI MAB_1609c|M.abscessus_ATCC_199 SAGVVIPLSALGVIVA--PTAAADCVN-----------------ANGTTL MSMEG_5499|M.smegmatis_MC2_155 ITGFALALAPFGTVVVDPPPARADCTS-----------------SGYATV MLBr_01556|M.leprae_Br4923 SKEVLARLNEQGEFVKSASSTVEAPVARRLRESFGG--IKPAADKGAEQV MAV_3693|M.avium_104 SKEVLARLNEQGEFVKSASSTVEAPVARRLRESFGGGKAAEGAAKAPAKA Mb1485c|M.bovis_AF2122/97 APLATLEHNVLNALNAPTQALLGRPLIG--DGAAGAPGTGQAGGAGGILW MUL_3062|M.ulcerans_Agy99 SFLQDPLQTALNATNKPVQDLTGRPLVG--NGANGVPGTGANGAAGGWLL Rv3512|M.tuberculosis_H37Rv GGAGGKGGNGGDAGKAGTGSAPGTAGTGGDGGKGGNGGIGAAGTTGPVGT TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK CSQGDVRGTNSGTGPVGS----------------------SGPYVP-YPC Mvan_1637|M.vanbaalenii_PYR-1 CSQGEVRGSTGGGGP-------------------------SGPYVP-YPC MAB_1609c|M.abscessus_ATCC_199 CAQGDVRG-GGSTTS-------------------------STPYVP-YPC MSMEG_5499|M.smegmatis_MC2_155 CAQGEVRGTDGVPRA-------------------------ATPVVP-YPC MLBr_01556|M.leprae_Br4923 ATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHSAAVVPIVAG MAV_3693|M.avium_104 AAKGDAKTAAKGDVKAPDKALDAALDN--AIKAGGNGEAAAPPAQPGGTA Mb1485c|M.bovis_AF2122/97 GN-GGAGGSGAPGQVGGAGGAAGLFGTGGAGGAGGAGAAGGAGGSGGWLL MUL_3062|M.ulcerans_Agy99 GN-GGAGGSGAAGQAGGDGGAAGLIGAGGAGGAGGNSPLRNTANGG---- Rv3512|M.tuberculosis_H37Rv GASGGTGGSGGAGGTGGDGGAANG-GTAGAGGAGGNGGKGGDGGAGVTSS TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK DWNYYNCNEWWDVDFDVDLD-PGRPGIGGPGGPGGPGIGA---------- Mvan_1637|M.vanbaalenii_PYR-1 DLNYYECNEWWDFDADIDID-PGPPGIGAPGRPDIGGPGR---------- MAB_1609c|M.abscessus_ATCC_199 ESDWSCDNWEMDIILGSDHESPPPPTVNPSPPPDFGRPGR---------- MSMEG_5499|M.smegmatis_MC2_155 EYDWYCG-TDVDLDIGWDPGRPDRP----------NRPNR---------- MLBr_01556|M.leprae_Br4923 EGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGH---------- MAV_3693|M.avium_104 TTPAAQATPEAPARPGPAAARPSAPAPGQPKPPAPGQPPR---------- Mb1485c|M.bovis_AF2122/97 GNGGVGGAGGQSLLGGATGGAGGNAGLFGVGGTGGPGGPGGPGGPGGPGG MUL_3062|M.ulcerans_Agy99 -NGGTGGAGGLLFGPGGVGGAGGAS--FLTGGTGGDGGAGG--------- Rv3512|M.tuberculosis_H37Rv TAGNSGGAGG-SGGKGGDAGAGGAGATPGANGIAGNGGDGGDGAAGAVGI TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -PGGPGRPGGG--------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -PGG-GRPG----------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -PGG---------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -PGG---------------------------------------------- MLBr_01556|M.leprae_Br4923 -PGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPP-------- MAV_3693|M.avium_104 -PGATPGPRPGPAPKPAARTPRVGNNPFSSAQPVDRPIPRPVPRPGAPRP Mb1485c|M.bovis_AF2122/97 PGGVGGTGGAGGLGGTLYGAGGHGGAGGPGPIGGVGGHGGVGGAAGLLGV MUL_3062|M.ulcerans_Agy99 ----------------LFGAGGLGGVGGSG---NVGGNGGAGGAGGLL-- Rv3512|M.tuberculosis_H37Rv SGATGAGDGGHGGTGAAGGNGGTGGAGGSGIDGVGGGTGGTGGNGGNGAI TH_3810|M.thermoresistible__bu ----------------------------------VDGDGGSGGRTGLFS- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK ----------------------------------FGGGGGRGGGGRR--- Mvan_1637|M.vanbaalenii_PYR-1 -----------------------------------GGGGGIGGGRGR--- MAB_1609c|M.abscessus_ATCC_199 -----------------------------------GGGGGGSIVRPR--- MSMEG_5499|M.smegmatis_MC2_155 -----------------------------------GGG-----IGPR--- MLBr_01556|M.leprae_Br4923 -APRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDA MAV_3693|M.avium_104 GAPRPGASPGNMPPRPGGVGGPG--RPARPGAPRPGGGRPGGP-GGR-DG Mb1485c|M.bovis_AF2122/97 GGHGGAGGHGAAGIAGAAGKGGIFPDGSNGGAGGDAGDGGTGGRGGWLAG MUL_3062|M.ulcerans_Agy99 -----------AGLVGAGGG-----DGGSGGLGAAGGDGGNGGRAGLFGG Rv3512|M.tuberculosis_H37Rv GG--------AGGDAGGSGN-----SGGNGGIGGKGGNAGAGGAAGSNGG TH_3810|M.thermoresistible__bu --------------KLSRGG-----DGGDGGLGGNGGHGGGTGIISLLSL MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 GGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAGAFGRPG MAV_3693|M.avium_104 GGGNYRGGGVGAPPGGG-GGFRGRPGG---GGGGRPGQRGGAAGAFGRPG Mb1485c|M.bovis_AF2122/97 AGGAGGDGGIGGTGGAGGAGFSRALIVA--GDNGGDGGNGGMGGAGGAGG MUL_3062|M.ulcerans_Agy99 AGGAGG---MGATG----------------GHSGGDGGAG--GDAG---- Rv3512|M.tuberculosis_H37Rv TVGANGTGGDGGNGGAAGAATAGSNGGAGTGSAGGNGGTGGRGGSGG--- TH_3810|M.thermoresistible__bu AG------------------------------NGGNGGNG---------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 GAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLS--- MAV_3693|M.avium_104 GAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLS--- Mb1485c|M.bovis_AF2122/97 PGGAGGLISLLGGQGAGGDGGDGGAGGVGGDRGAGANGNQAVNAGAGGAG MUL_3062|M.ulcerans_Agy99 ---------LLFGTG-----------------------------GAGGAG Rv3512|M.tuberculosis_H37Rv ----------AGGDGIGG--------------------------VGGGKG TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAV_3693|M.avium_104 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GHGGDPGAGGAGGTGGAGSTIGAHGAAGASPTSGGNGGAGGNGAHFSSGG MUL_3062|M.ulcerans_Agy99 GHAFD-GDGGAGGAG---------GNAGLMFSSGGSGGVGG------AGS Rv3512|M.tuberculosis_H37Rv GNGADGEVGGAGGAG----------GSGPNTSPGGNGGQGGQGGSGGAGG TH_3810|M.thermoresistible__bu -----------------------------YRTTDNN-------------A MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ----------------------------DFAEKIDANPAALVQALFNLGE MAV_3693|M.avium_104 ----------------------------DFAEKIDANPASLVQALFNLGE Mb1485c|M.bovis_AF2122/97 KAGGNGGAGGAGGLVGNGGAGGAGGNGAPGAPPSGGDPNGGGGGAGGAGG MUL_3062|M.ulcerans_Agy99 IDGGAGGAGGDAGWLGGGGAGGAGGFGTISD--------------GGAGG Rv3512|M.tuberculosis_H37Rv AAGAGGAGGGANGTAGNGGQGGAGGTGGAGAASSATN-----GGSGGAGG TH_3810|M.thermoresistible__bu LDGGHGGNGGNVGFFSLFNLGGAGG------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 MVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGD MAV_3693|M.avium_104 MVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLESFDLTYGEDEGT Mb1485c|M.bovis_AF2122/97 KGGDGGA--QAGDGGAGGAGGKGGNGGNGATGATGLNGLGAGADGTDGGK MUL_3062|M.ulcerans_Agy99 RGGGGGQ--LLGNGGAGGAGGQGGN------------------------- Rv3512|M.tuberculosis_H37Rv TGGDGGSGGAGGTGGAGGTGGAAGDGGQGGQG------------------ TH_3810|M.thermoresistible__bu ----------WGGSGVDGVDVVGGN------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 EDELQVRPPVVTVMGHVDHGKTRLLDTIRKAN------------------ MAV_3693|M.avium_104 EEDLQTRPPVVTVMGHVDHGKTRLLDTIRKAN------------------ Mb1485c|M.bovis_AF2122/97 GGNGGAGGGGGAGGQGGKALAATHQDGSMGAGGAGGNGGAGGMGGDGGNG MUL_3062|M.ulcerans_Agy99 ------------------------------------DGGAGGLGGNG--- Rv3512|M.tuberculosis_H37Rv ----------------------------------GAGGGAGGQGGAG--- TH_3810|M.thermoresistible__bu -----------------------------------PDGGTPGAHGES--- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAV_3693|M.avium_104 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 AKGTFDNGGDGVGGNGGNGGSRGIGGAGGIGGAGSTAGADGARGATPTSG MUL_3062|M.ulcerans_Agy99 ----------VLIGNGGNGG---------VGGVGETPGGD---------- Rv3512|M.tuberculosis_H37Rv ----------GAGGTGGNGGN-------ITGGTAGTAGAAG--------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAV_3693|M.avium_104 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GNGGTGGNGANATVAGGAGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGS MUL_3062|M.ulcerans_Agy99 -----GGGGISGLLLGADG-------FNAPAGSSPVHALQQQALAAINAP Rv3512|M.tuberculosis_H37Rv ----NGGAAGKGGAGGQGGTGGGTGGQGGAGGDGGAGGTGGDRTVG-GGT TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ---------VREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFT MAV_3693|M.avium_104 ---------VREAEQ-----------VTVEHDGVERPITFIDTPGHEAFT Mb1485c|M.bovis_AF2122/97 SPTTAGESGTSGQNGGAGGAGGAGGRGGDFGGDGGTGGAGGNGADGGAGG MUL_3062|M.ulcerans_Agy99 VQELTGRPLIGNGLPGSAGSGAAGAPGGWLLGDGGAG------------- Rv3512|M.tuberculosis_H37Rv VPAGSGGQGGNAGGGGAGGQGGADGGSGGDGGDAGTGG------------ TH_3810|M.thermoresistible__bu -----HTPGVYTDRQGEDGEDGTGTGIGGRGGNGGS-------------- MMAR_3811|M.marinum_M ----------MKTYPRLAATGLAMVLG---LGLAGVG------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 AMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVP---------- MAV_3693|M.avium_104 AMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVP---------- Mb1485c|M.bovis_AF2122/97 NGANGANATTPGAKGGDGGHGGPGAQGGNGGQGGPGGLAGNLFGQNGIQG MUL_3062|M.ulcerans_Agy99 ----GSAAATPGAAGGAGGAAGLVGAGGAGGAGANTGISN--------PG Rv3512|M.tuberculosis_H37Rv ---NGGNGGNRNSGNGTGGAGGNGGGGANGGAGGAGGSGG---------G TH_3810|M.thermoresistible__bu -----SSGTHPMAEDGEHVKALDGRPGLDGGNGSHG-------------- MMAR_3811|M.marinum_M ------VASEAAAQPGAPTQWCPGDFWDPG-------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ----IVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVG MAV_3693|M.avium_104 ----IVVAVNKIDVEGADPQKIRGQLTEYGLVPEEFGGDTMFVDISAKQG Mb1485c|M.bovis_AF2122/97 VGGSGGKGGAGGLAGDGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSG MUL_3062|M.ulcerans_Agy99 FGGAGGAGGAG--AGAGG-----------GVGEAGGAGGLLGAGGTGGGG Rv3512|M.tuberculosis_H37Rv TGGNGGAGGDAGDAGNGGNGN------GTGNGGNGGNGGIAGMGGNGGAG TH_3810|M.thermoresistible__bu -----------------------------GNGGHGGRGGFLGIGGSGGWG MMAR_3811|M.marinum_M -------------------------------WGQNWDMGHCHDNWRGPGP Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 TNIEALLEAVLLTADAALDLR--------ANSGMEAQGVAIEAHLDRGRG MAV_3693|M.avium_104 TNIDQLLEAVLLTADAALDLR--------ANPDMEAQGVAIEAHLDRGRG Mb1485c|M.bovis_AF2122/97 GAGSTPGAKGAHGFTPTSGGDGGDGGNGGHSQVVGGNGGDGGNGGNGGSA MUL_3062|M.ulcerans_Agy99 GVAP--------------------------SLVDGGTGGAGGAGGAGG-- Rv3512|M.tuberculosis_H37Rv TGSG-----------------------------NGGNGGSGGNGGNAG-- TH_3810|M.thermoresistible__bu -----------------------------------GHGGNGGDTDADG-- MMAR_3811|M.marinum_M NPQP-------------------------------GHAGPGGPGEPAP-- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 PVAT--------------------------VLVQRGTLRIGDSVVAGDAY MAV_3693|M.avium_104 PVAT--------------------------VLIQRGTLRVGDSIVAGDAY Mb1485c|M.bovis_AF2122/97 GTGGNGGRGGDGAFGGMSANATNPGENGPNGNPGGNGGAGGAGGAGLNGG MUL_3062|M.ulcerans_Agy99 ------------LFG------------GIFGAGGGDGGAG-----GFTGG Rv3512|M.tuberculosis_H37Rv -------------MGGNSGTGSGDGGAGGNGGAAGTGGTGGDGGLTGTGG TH_3810|M.thermoresistible__bu ----------------------------------GNGGDG---------G MMAR_3811|M.marinum_M -------------------------------------------------G Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 G-----------------------RVRRMVDEHGVDIEAALPSSPVQVIG MAV_3693|M.avium_104 G-----------------------RVRRMVDEHGDDVEEALPSRPVQVIG Mb1485c|M.bovis_AF2122/97 NGGAGGNGGLGGFGGNGAAGANGVAVGAPGQPGGAGGHGGAGGNGGAGGN MUL_3062|M.ulcerans_Agy99 IDGAGGVGGAG------------------------GNTGLLGGPGGSGGS Rv3512|M.tuberculosis_H37Rv TGGSGGTGGDGGNGGNGADN----TANMTAQAGGDGGNGGDGGFGGGAGA TH_3810|M.thermoresistible__bu NGGSAGRGGTG---------------------------GLRGVFGINGGN MMAR_3811|M.marinum_M QQGPGGPGGPG---------------------------------GPGEGP Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 FTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDS MAV_3693|M.avium_104 FTSVPGAGDNLLVVDEDRIARQIADKRSARKRNALAARSRKRISLEDLDS Mb1485c|M.bovis_AF2122/97 GGQGVVSDGAGGAGGAGGDGGAPGDGANGGNGQGAGAFAGGGGGRGGDGG MUL_3062|M.ulcerans_Agy99 GGDGIAKLGFNVDGGAGGAG------VNGG-------FLFGSGGTGGFGG Rv3512|M.tuberculosis_H37Rv GGGGLT-AGANGTGGQGGAGGDGGNGAIGGHG----PLTDDPGGNGGTGG TH_3810|M.thermoresistible__bu GRAGLGGRGXXXXGGGVG--------------------AAVRSGNGVFSG MMAR_3811|M.marinum_M GGPGGPGEGPGGPGGPH--------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITE MAV_3693|M.avium_104 ALKETSQLNLILKGDNAGTVEALEEALMGIQIDDEVALRVIDRGVGGITE Mb1485c|M.bovis_AF2122/97 NAGNAGAGGPGGTGSTAGKAGPAGSILHDGGNGGHGGHGAASGGNGGPGG MUL_3062|M.ulcerans_Agy99 VG---GVGTSTGIGGAGGRGGNAGLLFSDAGVGGFG-------------- Rv3512|M.tuberculosis_H37Rv NGGTGGTGG-AGIGSLGGGTGGDGGNGGNGGTGGEGGE------------ TH_3810|M.thermoresistible__bu GG-----------GTPSAGFGVPTTIQFPAG------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 TNVNLASASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAID---- MAV_3693|M.avium_104 TNVNLASASDAVIIGFNVRAEGKATELANREGVEIRYYSVIYQAID---- Mb1485c|M.bovis_AF2122/97 HGGNGGNGGTGANGGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGGNG MUL_3062|M.ulcerans_Agy99 -----GFGGTGGNAGWLGSGGSGGAG--------------GGSNGDGGAG Rv3512|M.tuberculosis_H37Rv ---VGGAGGTGGAAGNGGDGGTGGTG--------------GGDGGAGGTG TH_3810|M.thermoresistible__bu -------SCTSRAVSREGIMPS-----------------------SRAAS MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ---DIEKALRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVR MAV_3693|M.avium_104 ---EIEKALRGMLKPIYEENQLGRAEIRAIFRSSKVGIIAGCMITSGVVR Mb1485c|M.bovis_AF2122/97 GRGGNGGQGLTGAGGNGGTGGTPGNGGNGGNGASGDLVTSPGDGGGGGRG MUL_3062|M.ulcerans_Agy99 GTGGSGGQ-------------IVGDGGAGGAGGQGDLLAAGGSGGDGGQG Rv3512|M.tuberculosis_H37Rv GTGGTGGLGDPRVGGSGGDGGTGGSGGAAGNGGNGGNAGAGGNG-NGGTG TH_3810|M.thermoresistible__bu ARAG-------------------AACASSTSRSRRSFCCSRA-------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 RNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKE MAV_3693|M.avium_104 RNAKARLLRDNVVVSENLTINSLRREKDDVTEVREGFECGMTLGYSDIKE Mb1485c|M.bovis_AF2122/97 GDAGRGGDAGLGGSSGPGGTPGDWGTGGTGGTGGTGGQGANGGLTGGRGG MUL_3062|M.ulcerans_Agy99 GDAVLIG------------------------TGGNGGNGASGVLAG---- Rv3512|M.tuberculosis_H37Rv GAGGIGG------------------------TGGNGGDAEPGVPPG---- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 GDVIESYELVEKQRA----------------------------------- MAV_3693|M.avium_104 GDVIESYELVQKERT----------------------------------- Mb1485c|M.bovis_AF2122/97 TGGNGGAGGTGGTGHNGSQPGMGGNGGAGGFGGNGFAGVGGRGGMGGSGG MUL_3062|M.ulcerans_Agy99 ---------------------IGGDGGS-------------RGLLLGEDG Rv3512|M.tuberculosis_H37Rv ------AGGAGGAGTTGGKGGTGGNGSGTG-----------SGGTGGDGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAV_3693|M.avium_104 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 TGGTGDAGPFGTGTGGTGGHGGQGGGGGFSILLGLGGLGGLGSPGSIATG MUL_3062|M.ulcerans_Agy99 VN--GEAAPP------------------MTHIVLLG--GDFPAAAS---- Rv3512|M.tuberculosis_H37Rv TGGGGGNGGTG-------------WNGGKGDTGSGGGAGDGGKAPAGGTG TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAV_3693|M.avium_104 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 TAGGAGGGGGFGGLGGGEFV MUL_3062|M.ulcerans_Agy99 -------------------- Rv3512|M.tuberculosis_H37Rv GAGGDGGAGGKGGSGGV--- TH_3810|M.thermoresistible__bu -------------------- MMAR_3811|M.marinum_M -------------------- Mflv_4805|M.gilvum_PYR-GCK -------------------- Mvan_1637|M.vanbaalenii_PYR-1 -------------------- MAB_1609c|M.abscessus_ATCC_199 -------------------- MSMEG_5499|M.smegmatis_MC2_155 -------------------- MLBr_01556|M.leprae_Br4923 -------------------- MAV_3693|M.avium_104 --------------------