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M. gilvum PYR-GCK Mflv_4805 (-)

annotation: hypothetical protein Mflv_4805
coordinates: 5112186 - 5112563
length: 125

HMIAVVMTPVVSLATVVAVAAPAAADCTTAGATTICSQGDVRGTNSGTGPVGSSGPYVPYPCDWNYYNCN
EWWDVDFDVDLDPGRPGIGGPGGPGGPGIGAPGGPGRPGGGFGGGGGRGGGGRR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4805--100% (125)hypothetical protein Mflv_4805
M. gilvum PYR-GCKMflv_4039infB7e-0863.04% (46) translation initiation factor IF-2
M. gilvum PYR-GCKMflv_5091-1e-0736.21% (116) triple helix repeat-containing collagen

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1485cPE_PGRS272e-0969.23% (39) PE-PGRS family protein
M. tuberculosis H37RvRv3512PE_PGRS562e-0836.27% (102) PE-PGRS family protein
M. leprae Br4923MLBr_01556infB1e-0550.00% (52) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_1609c-3e-1844.44% (117) hypothetical protein MAB_1609c
M. marinum MMMAR_3811-7e-1074.29% (35) hypothetical protein MMAR_3811
M. avium 104MAV_3693infB3e-0860.47% (43) translation initiation factor IF-2
M. smegmatis MC2 155MSMEG_5499-4e-1740.00% (115) hypothetical protein MSMEG_5499
M. thermoresistible (build 8)TH_3810-1e-0534.29% (105) PUTATIVE -
M. ulcerans Agy99MUL_3062-6e-0861.54% (39) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1637-3e-4264.46% (121) hypothetical protein Mvan_1637

CLUSTAL 2.0.9 multiple sequence alignment


Mb1485c|M.bovis_AF2122/97           MSLVIVAPETVAAAALDVARIGSSIGVANSAAAGSTTSVLAAGADEVSAA
MUL_3062|M.ulcerans_Agy99           MAFVLAVPDMVAEAAADLAGVGSVIDAANTAAAGSTTGIVAAAEDEVSAA
Rv3512|M.tuberculosis_H37Rv         -----------PQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          ------------------------------------------MH-----M
Mvan_1637|M.vanbaalenii_PYR-1       ------------------------------------------MR-----L
MAB_1609c|M.abscessus_ATCC_199      ------------------------------------------MRTMRCYL
MSMEG_5499|M.smegmatis_MC2_155      ------------------------------------------MRSTQRYL
MLBr_01556|M.leprae_Br4923          ---------------------------------MAGKARVHELAKELGVT
MAV_3693|M.avium_104                ---------------------------------MAGKARVHELAKELGVT
                                                                                      

Mb1485c|M.bovis_AF2122/97           IATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSYVS-----AEATNA
MUL_3062|M.ulcerans_Agy99           IAALFSGHGQAYQQISTRVAEFHAQFERVFAAGVQAYSG-----AEAANA
Rv3512|M.tuberculosis_H37Rv         GAGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGDGALAGSS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          IAVVMTPVVSLATVVAVAAPAAADCTT-----------------AGATTI
Mvan_1637|M.vanbaalenii_PYR-1       VYLIAVPVV-VSTGIAIAPPAVADCTS-----------------AGGTTI
MAB_1609c|M.abscessus_ATCC_199      SAGVVIPLSALGVIVA--PTAAADCVN-----------------ANGTTL
MSMEG_5499|M.smegmatis_MC2_155      ITGFALALAPFGTVVVDPPPARADCTS-----------------SGYATV
MLBr_01556|M.leprae_Br4923          SKEVLARLNEQGEFVKSASSTVEAPVARRLRESFGG--IKPAADKGAEQV
MAV_3693|M.avium_104                SKEVLARLNEQGEFVKSASSTVEAPVARRLRESFGGGKAAEGAAKAPAKA
                                                                                      

Mb1485c|M.bovis_AF2122/97           APLATLEHNVLNALNAPTQALLGRPLIG--DGAAGAPGTGQAGGAGGILW
MUL_3062|M.ulcerans_Agy99           SFLQDPLQTALNATNKPVQDLTGRPLVG--NGANGVPGTGANGAAGGWLL
Rv3512|M.tuberculosis_H37Rv         GGAGGKGGNGGDAGKAGTGSAPGTAGTGGDGGKGGNGGIGAAGTTGPVGT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          CSQGDVRGTNSGTGPVGS----------------------SGPYVP-YPC
Mvan_1637|M.vanbaalenii_PYR-1       CSQGEVRGSTGGGGP-------------------------SGPYVP-YPC
MAB_1609c|M.abscessus_ATCC_199      CAQGDVRG-GGSTTS-------------------------STPYVP-YPC
MSMEG_5499|M.smegmatis_MC2_155      CAQGEVRGTDGVPRA-------------------------ATPVVP-YPC
MLBr_01556|M.leprae_Br4923          ATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHSAAVVPIVAG
MAV_3693|M.avium_104                AAKGDAKTAAKGDVKAPDKALDAALDN--AIKAGGNGEAAAPPAQPGGTA
                                                                                      

Mb1485c|M.bovis_AF2122/97           GN-GGAGGSGAPGQVGGAGGAAGLFGTGGAGGAGGAGAAGGAGGSGGWLL
MUL_3062|M.ulcerans_Agy99           GN-GGAGGSGAAGQAGGDGGAAGLIGAGGAGGAGGNSPLRNTANGG----
Rv3512|M.tuberculosis_H37Rv         GASGGTGGSGGAGGTGGDGGAANG-GTAGAGGAGGNGGKGGDGGAGVTSS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          DWNYYNCNEWWDVDFDVDLD-PGRPGIGGPGGPGGPGIGA----------
Mvan_1637|M.vanbaalenii_PYR-1       DLNYYECNEWWDFDADIDID-PGPPGIGAPGRPDIGGPGR----------
MAB_1609c|M.abscessus_ATCC_199      ESDWSCDNWEMDIILGSDHESPPPPTVNPSPPPDFGRPGR----------
MSMEG_5499|M.smegmatis_MC2_155      EYDWYCG-TDVDLDIGWDPGRPDRP----------NRPNR----------
MLBr_01556|M.leprae_Br4923          EGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGH----------
MAV_3693|M.avium_104                TTPAAQATPEAPARPGPAAARPSAPAPGQPKPPAPGQPPR----------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GNGGVGGAGGQSLLGGATGGAGGNAGLFGVGGTGGPGGPGGPGGPGGPGG
MUL_3062|M.ulcerans_Agy99           -NGGTGGAGGLLFGPGGVGGAGGAS--FLTGGTGGDGGAGG---------
Rv3512|M.tuberculosis_H37Rv         TAGNSGGAGG-SGGKGGDAGAGGAGATPGANGIAGNGGDGGDGAAGAVGI
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          -PGGPGRPGGG---------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       -PGG-GRPG-----------------------------------------
MAB_1609c|M.abscessus_ATCC_199      -PGG----------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      -PGG----------------------------------------------
MLBr_01556|M.leprae_Br4923          -PGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPP--------
MAV_3693|M.avium_104                -PGATPGPRPGPAPKPAARTPRVGNNPFSSAQPVDRPIPRPVPRPGAPRP
                                                                                      

Mb1485c|M.bovis_AF2122/97           PGGVGGTGGAGGLGGTLYGAGGHGGAGGPGPIGGVGGHGGVGGAAGLLGV
MUL_3062|M.ulcerans_Agy99           ----------------LFGAGGLGGVGGSG---NVGGNGGAGGAGGLL--
Rv3512|M.tuberculosis_H37Rv         SGATGAGDGGHGGTGAAGGNGGTGGAGGSGIDGVGGGTGGTGGNGGNGAI
TH_3810|M.thermoresistible__bu      ----------------------------------VDGDGGSGGRTGLFS-
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          ----------------------------------FGGGGGRGGGGRR---
Mvan_1637|M.vanbaalenii_PYR-1       -----------------------------------GGGGGIGGGRGR---
MAB_1609c|M.abscessus_ATCC_199      -----------------------------------GGGGGGSIVRPR---
MSMEG_5499|M.smegmatis_MC2_155      -----------------------------------GGG-----IGPR---
MLBr_01556|M.leprae_Br4923          -APRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDA
MAV_3693|M.avium_104                GAPRPGASPGNMPPRPGGVGGPG--RPARPGAPRPGGGRPGGP-GGR-DG
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGHGGAGGHGAAGIAGAAGKGGIFPDGSNGGAGGDAGDGGTGGRGGWLAG
MUL_3062|M.ulcerans_Agy99           -----------AGLVGAGGG-----DGGSGGLGAAGGDGGNGGRAGLFGG
Rv3512|M.tuberculosis_H37Rv         GG--------AGGDAGGSGN-----SGGNGGIGGKGGNAGAGGAAGSNGG
TH_3810|M.thermoresistible__bu      --------------KLSRGG-----DGGDGGLGGNGGHGGGTGIISLLSL
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          GGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAGAFGRPG
MAV_3693|M.avium_104                GGGNYRGGGVGAPPGGG-GGFRGRPGG---GGGGRPGQRGGAAGAFGRPG
                                                                                      

Mb1485c|M.bovis_AF2122/97           AGGAGGDGGIGGTGGAGGAGFSRALIVA--GDNGGDGGNGGMGGAGGAGG
MUL_3062|M.ulcerans_Agy99           AGGAGG---MGATG----------------GHSGGDGGAG--GDAG----
Rv3512|M.tuberculosis_H37Rv         TVGANGTGGDGGNGGAAGAATAGSNGGAGTGSAGGNGGTGGRGGSGG---
TH_3810|M.thermoresistible__bu      AG------------------------------NGGNGGNG----------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          GAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLS---
MAV_3693|M.avium_104                GAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLS---
                                                                                      

Mb1485c|M.bovis_AF2122/97           PGGAGGLISLLGGQGAGGDGGDGGAGGVGGDRGAGANGNQAVNAGAGGAG
MUL_3062|M.ulcerans_Agy99           ---------LLFGTG-----------------------------GAGGAG
Rv3512|M.tuberculosis_H37Rv         ----------AGGDGIGG--------------------------VGGGKG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAV_3693|M.avium_104                --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GHGGDPGAGGAGGTGGAGSTIGAHGAAGASPTSGGNGGAGGNGAHFSSGG
MUL_3062|M.ulcerans_Agy99           GHAFD-GDGGAGGAG---------GNAGLMFSSGGSGGVGG------AGS
Rv3512|M.tuberculosis_H37Rv         GNGADGEVGGAGGAG----------GSGPNTSPGGNGGQGGQGGSGGAGG
TH_3810|M.thermoresistible__bu      -----------------------------YRTTDNN-------------A
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ----------------------------DFAEKIDANPAALVQALFNLGE
MAV_3693|M.avium_104                ----------------------------DFAEKIDANPASLVQALFNLGE
                                                                                      

Mb1485c|M.bovis_AF2122/97           KAGGNGGAGGAGGLVGNGGAGGAGGNGAPGAPPSGGDPNGGGGGAGGAGG
MUL_3062|M.ulcerans_Agy99           IDGGAGGAGGDAGWLGGGGAGGAGGFGTISD--------------GGAGG
Rv3512|M.tuberculosis_H37Rv         AAGAGGAGGGANGTAGNGGQGGAGGTGGAGAASSATN-----GGSGGAGG
TH_3810|M.thermoresistible__bu      LDGGHGGNGGNVGFFSLFNLGGAGG-------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          MVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGD
MAV_3693|M.avium_104                MVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLESFDLTYGEDEGT
                                                                                      

Mb1485c|M.bovis_AF2122/97           KGGDGGA--QAGDGGAGGAGGKGGNGGNGATGATGLNGLGAGADGTDGGK
MUL_3062|M.ulcerans_Agy99           RGGGGGQ--LLGNGGAGGAGGQGGN-------------------------
Rv3512|M.tuberculosis_H37Rv         TGGDGGSGGAGGTGGAGGTGGAAGDGGQGGQG------------------
TH_3810|M.thermoresistible__bu      ----------WGGSGVDGVDVVGGN-------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          EDELQVRPPVVTVMGHVDHGKTRLLDTIRKAN------------------
MAV_3693|M.avium_104                EEDLQTRPPVVTVMGHVDHGKTRLLDTIRKAN------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGNGGAGGGGGAGGQGGKALAATHQDGSMGAGGAGGNGGAGGMGGDGGNG
MUL_3062|M.ulcerans_Agy99           ------------------------------------DGGAGGLGGNG---
Rv3512|M.tuberculosis_H37Rv         ----------------------------------GAGGGAGGQGGAG---
TH_3810|M.thermoresistible__bu      -----------------------------------PDGGTPGAHGES---
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAV_3693|M.avium_104                --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           AKGTFDNGGDGVGGNGGNGGSRGIGGAGGIGGAGSTAGADGARGATPTSG
MUL_3062|M.ulcerans_Agy99           ----------VLIGNGGNGG---------VGGVGETPGGD----------
Rv3512|M.tuberculosis_H37Rv         ----------GAGGTGGNGGN-------ITGGTAGTAGAAG---------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAV_3693|M.avium_104                --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GNGGTGGNGANATVAGGAGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGS
MUL_3062|M.ulcerans_Agy99           -----GGGGISGLLLGADG-------FNAPAGSSPVHALQQQALAAINAP
Rv3512|M.tuberculosis_H37Rv         ----NGGAAGKGGAGGQGGTGGGTGGQGGAGGDGGAGGTGGDRTVG-GGT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ---------VREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFT
MAV_3693|M.avium_104                ---------VREAEQ-----------VTVEHDGVERPITFIDTPGHEAFT
                                                                                      

Mb1485c|M.bovis_AF2122/97           SPTTAGESGTSGQNGGAGGAGGAGGRGGDFGGDGGTGGAGGNGADGGAGG
MUL_3062|M.ulcerans_Agy99           VQELTGRPLIGNGLPGSAGSGAAGAPGGWLLGDGGAG-------------
Rv3512|M.tuberculosis_H37Rv         VPAGSGGQGGNAGGGGAGGQGGADGGSGGDGGDAGTGG------------
TH_3810|M.thermoresistible__bu      -----HTPGVYTDRQGEDGEDGTGTGIGGRGGNGGS--------------
MMAR_3811|M.marinum_M               ----------MKTYPRLAATGLAMVLG---LGLAGVG-------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          AMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVP----------
MAV_3693|M.avium_104                AMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVP----------
                                                                                      

Mb1485c|M.bovis_AF2122/97           NGANGANATTPGAKGGDGGHGGPGAQGGNGGQGGPGGLAGNLFGQNGIQG
MUL_3062|M.ulcerans_Agy99           ----GSAAATPGAAGGAGGAAGLVGAGGAGGAGANTGISN--------PG
Rv3512|M.tuberculosis_H37Rv         ---NGGNGGNRNSGNGTGGAGGNGGGGANGGAGGAGGSGG---------G
TH_3810|M.thermoresistible__bu      -----SSGTHPMAEDGEHVKALDGRPGLDGGNGSHG--------------
MMAR_3811|M.marinum_M               ------VASEAAAQPGAPTQWCPGDFWDPG--------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ----IVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVG
MAV_3693|M.avium_104                ----IVVAVNKIDVEGADPQKIRGQLTEYGLVPEEFGGDTMFVDISAKQG
                                                                                      

Mb1485c|M.bovis_AF2122/97           VGGSGGKGGAGGLAGDGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSG
MUL_3062|M.ulcerans_Agy99           FGGAGGAGGAG--AGAGG-----------GVGEAGGAGGLLGAGGTGGGG
Rv3512|M.tuberculosis_H37Rv         TGGNGGAGGDAGDAGNGGNGN------GTGNGGNGGNGGIAGMGGNGGAG
TH_3810|M.thermoresistible__bu      -----------------------------GNGGHGGRGGFLGIGGSGGWG
MMAR_3811|M.marinum_M               -------------------------------WGQNWDMGHCHDNWRGPGP
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          TNIEALLEAVLLTADAALDLR--------ANSGMEAQGVAIEAHLDRGRG
MAV_3693|M.avium_104                TNIDQLLEAVLLTADAALDLR--------ANPDMEAQGVAIEAHLDRGRG
                                                                                      

Mb1485c|M.bovis_AF2122/97           GAGSTPGAKGAHGFTPTSGGDGGDGGNGGHSQVVGGNGGDGGNGGNGGSA
MUL_3062|M.ulcerans_Agy99           GVAP--------------------------SLVDGGTGGAGGAGGAGG--
Rv3512|M.tuberculosis_H37Rv         TGSG-----------------------------NGGNGGSGGNGGNAG--
TH_3810|M.thermoresistible__bu      -----------------------------------GHGGNGGDTDADG--
MMAR_3811|M.marinum_M               NPQP-------------------------------GHAGPGGPGEPAP--
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          PVAT--------------------------VLVQRGTLRIGDSVVAGDAY
MAV_3693|M.avium_104                PVAT--------------------------VLIQRGTLRVGDSIVAGDAY
                                                                                      

Mb1485c|M.bovis_AF2122/97           GTGGNGGRGGDGAFGGMSANATNPGENGPNGNPGGNGGAGGAGGAGLNGG
MUL_3062|M.ulcerans_Agy99           ------------LFG------------GIFGAGGGDGGAG-----GFTGG
Rv3512|M.tuberculosis_H37Rv         -------------MGGNSGTGSGDGGAGGNGGAAGTGGTGGDGGLTGTGG
TH_3810|M.thermoresistible__bu      ----------------------------------GNGGDG---------G
MMAR_3811|M.marinum_M               -------------------------------------------------G
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          G-----------------------RVRRMVDEHGVDIEAALPSSPVQVIG
MAV_3693|M.avium_104                G-----------------------RVRRMVDEHGDDVEEALPSRPVQVIG
                                                                                      

Mb1485c|M.bovis_AF2122/97           NGGAGGNGGLGGFGGNGAAGANGVAVGAPGQPGGAGGHGGAGGNGGAGGN
MUL_3062|M.ulcerans_Agy99           IDGAGGVGGAG------------------------GNTGLLGGPGGSGGS
Rv3512|M.tuberculosis_H37Rv         TGGSGGTGGDGGNGGNGADN----TANMTAQAGGDGGNGGDGGFGGGAGA
TH_3810|M.thermoresistible__bu      NGGSAGRGGTG---------------------------GLRGVFGINGGN
MMAR_3811|M.marinum_M               QQGPGGPGGPG---------------------------------GPGEGP
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          FTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDS
MAV_3693|M.avium_104                FTSVPGAGDNLLVVDEDRIARQIADKRSARKRNALAARSRKRISLEDLDS
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGQGVVSDGAGGAGGAGGDGGAPGDGANGGNGQGAGAFAGGGGGRGGDGG
MUL_3062|M.ulcerans_Agy99           GGDGIAKLGFNVDGGAGGAG------VNGG-------FLFGSGGTGGFGG
Rv3512|M.tuberculosis_H37Rv         GGGGLT-AGANGTGGQGGAGGDGGNGAIGGHG----PLTDDPGGNGGTGG
TH_3810|M.thermoresistible__bu      GRAGLGGRGXXXXGGGVG--------------------AAVRSGNGVFSG
MMAR_3811|M.marinum_M               GGPGGPGEGPGGPGGPH---------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITE
MAV_3693|M.avium_104                ALKETSQLNLILKGDNAGTVEALEEALMGIQIDDEVALRVIDRGVGGITE
                                                                                      

Mb1485c|M.bovis_AF2122/97           NAGNAGAGGPGGTGSTAGKAGPAGSILHDGGNGGHGGHGAASGGNGGPGG
MUL_3062|M.ulcerans_Agy99           VG---GVGTSTGIGGAGGRGGNAGLLFSDAGVGGFG--------------
Rv3512|M.tuberculosis_H37Rv         NGGTGGTGG-AGIGSLGGGTGGDGGNGGNGGTGGEGGE------------
TH_3810|M.thermoresistible__bu      GG-----------GTPSAGFGVPTTIQFPAG-------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          TNVNLASASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAID----
MAV_3693|M.avium_104                TNVNLASASDAVIIGFNVRAEGKATELANREGVEIRYYSVIYQAID----
                                                                                      

Mb1485c|M.bovis_AF2122/97           HGGNGGNGGTGANGGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGGNG
MUL_3062|M.ulcerans_Agy99           -----GFGGTGGNAGWLGSGGSGGAG--------------GGSNGDGGAG
Rv3512|M.tuberculosis_H37Rv         ---VGGAGGTGGAAGNGGDGGTGGTG--------------GGDGGAGGTG
TH_3810|M.thermoresistible__bu      -------SCTSRAVSREGIMPS-----------------------SRAAS
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ---DIEKALRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVR
MAV_3693|M.avium_104                ---EIEKALRGMLKPIYEENQLGRAEIRAIFRSSKVGIIAGCMITSGVVR
                                                                                      

Mb1485c|M.bovis_AF2122/97           GRGGNGGQGLTGAGGNGGTGGTPGNGGNGGNGASGDLVTSPGDGGGGGRG
MUL_3062|M.ulcerans_Agy99           GTGGSGGQ-------------IVGDGGAGGAGGQGDLLAAGGSGGDGGQG
Rv3512|M.tuberculosis_H37Rv         GTGGTGGLGDPRVGGSGGDGGTGGSGGAAGNGGNGGNAGAGGNG-NGGTG
TH_3810|M.thermoresistible__bu      ARAG-------------------AACASSTSRSRRSFCCSRA--------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          RNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKE
MAV_3693|M.avium_104                RNAKARLLRDNVVVSENLTINSLRREKDDVTEVREGFECGMTLGYSDIKE
                                                                                      

Mb1485c|M.bovis_AF2122/97           GDAGRGGDAGLGGSSGPGGTPGDWGTGGTGGTGGTGGQGANGGLTGGRGG
MUL_3062|M.ulcerans_Agy99           GDAVLIG------------------------TGGNGGNGASGVLAG----
Rv3512|M.tuberculosis_H37Rv         GAGGIGG------------------------TGGNGGDAEPGVPPG----
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          GDVIESYELVEKQRA-----------------------------------
MAV_3693|M.avium_104                GDVIESYELVQKERT-----------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           TGGNGGAGGTGGTGHNGSQPGMGGNGGAGGFGGNGFAGVGGRGGMGGSGG
MUL_3062|M.ulcerans_Agy99           ---------------------IGGDGGS-------------RGLLLGEDG
Rv3512|M.tuberculosis_H37Rv         ------AGGAGGAGTTGGKGGTGGNGSGTG-----------SGGTGGDGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAV_3693|M.avium_104                --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           TGGTGDAGPFGTGTGGTGGHGGQGGGGGFSILLGLGGLGGLGSPGSIATG
MUL_3062|M.ulcerans_Agy99           VN--GEAAPP------------------MTHIVLLG--GDFPAAAS----
Rv3512|M.tuberculosis_H37Rv         TGGGGGNGGTG-------------WNGGKGDTGSGGGAGDGGKAPAGGTG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAV_3693|M.avium_104                --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           TAGGAGGGGGFGGLGGGEFV
MUL_3062|M.ulcerans_Agy99           --------------------
Rv3512|M.tuberculosis_H37Rv         GAGGDGGAGGKGGSGGV---
TH_3810|M.thermoresistible__bu      --------------------
MMAR_3811|M.marinum_M               --------------------
Mflv_4805|M.gilvum_PYR-GCK          --------------------
Mvan_1637|M.vanbaalenii_PYR-1       --------------------
MAB_1609c|M.abscessus_ATCC_199      --------------------
MSMEG_5499|M.smegmatis_MC2_155      --------------------
MLBr_01556|M.leprae_Br4923          --------------------
MAV_3693|M.avium_104                --------------------