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LKRLVLESEHEAFRETVRQFIDQELVPNAEKWETNRLVDRSAWVAAGKYGLIGFNMPEQYGGSGVDDFRF NAVIDEEIARYGGPAPALSLQNDVVGPYFSSLSNDEQKERWLPGITTGELIVAVAMTEPGAGSDLAGIRT SAVRDGDDWIINGAKTFISSGINCDLVVVVCRTDPDAGHKGFTLFVVEAGMDGFTRGRKLDKMGLHYQDT AELNFDNVRVPSANLLGKEGRGFYHLMHNLPSERLSIAISAIAGARETWRQTLQYAKDRKAFGQPIGSFQ HNRFMLAEMDTELEIGEQYIDRCLQAVVDGELTAVEAAKAKWWCTETAKKVIDGCVQLHGGYGYMTEYRV ARDYMDNRIMTIFGGTTEIMKDIIGRDLGL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1883 | - | - | 100% (380) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_2600 | - | 0.0 | 93.16% (380) | acyl-CoA dehydrogenase |
| M. avium 104 | MAV_3616 | - | e-126 | 55.94% (379) | long-chain specific acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2743c | fadE20 | 1e-122 | 55.91% (381) | acyl-CoA dehydrogenase FADE20 |
| M. gilvum PYR-GCK | Mflv_2118 | - | 0.0 | 80.26% (380) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv2724c | fadE20 | 1e-124 | 56.43% (381) | acyl-CoA dehydrogenase FADE20 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 5e-53 | 33.07% (375) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3040c | - | 1e-128 | 57.29% (377) | acyl-CoA dehydrogenase |
| M. marinum M | MMAR_1989 | fadE20 | 1e-123 | 55.38% (381) | acyl-CoA dehydrogenase FadE20 |
| M. smegmatis MC2 155 | MSMEG_5197 | - | 0.0 | 80.79% (380) | long-chain specific acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_4527 | - | 0.0 | 84.74% (380) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_3367 | fadE20 | 1e-120 | 54.59% (381) | acyl-CoA dehydrogenase FadE20 |
| M. vanbaalenii PYR-1 | Mvan_4587 | - | 0.0 | 81.32% (380) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2743c|M.bovis_AF2122/97 ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVDRG
Rv2724c|M.tuberculosis_H37Rv ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRG
MMAR_1989|M.marinum_M ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVAPYHDEWEKAKIVDRG
MUL_3367|M.ulcerans_Agy99 ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVDRG
MAB_3040c|M.abscessus_ATCC_199 ---MAGAVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVDRA
Mflv_2118|M.gilvum_PYR-GCK ---------MKRTIYDAEHEAFRDTVKEYIERELVPNSEKWETERIVDRS
Mvan_4587|M.vanbaalenii_PYR-1 ---------MKRTIYDAEHEAFRETVKEYIERELVPNSEKWETERIVDRS
MSMEG_5197|M.smegmatis_MC2_155 ---------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVDRS
TH_4527|M.thermoresistible__bu ---------MKRTVYEPEHEAFRETVREYIERELVPHAEKWETERIVDRS
MAV_1883|M.avium_104 ---------MKRLVLESEHEAFRETVRQFIDQELVPNAEKWETNRLVDRS
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
. **: :* : : ::. . : . .
Mb2743c|M.bovis_AF2122/97 VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFGLH
Rv2724c|M.tuberculosis_H37Rv VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFGLH
MMAR_1989|M.marinum_M VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYSGIGFGLH
MUL_3367|M.ulcerans_Agy99 VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYSGIGFGLH
MAB_3040c|M.abscessus_ATCC_199 LWVEAGKQGFLGTDMPEEFGGGGLIDFRYNTIITEEVTKGRHTGVGFSLH
Mflv_2118|M.gilvum_PYR-GCK AYTAAGKYGLIGFNMPEEFGGGGTDDFRFNAIIDEEIAKAGVHGPALSLH
Mvan_4587|M.vanbaalenii_PYR-1 AYTAAGKYGLIGFNMPEEYGGGGSEDFRFNAIIDEEMAKSGVHGPALSLH
MSMEG_5197|M.smegmatis_MC2_155 AYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIAKSGVHGPALSLH
TH_4527|M.thermoresistible__bu AYVAAGKYGLIGFNMPEKYGGGGTDDFRFNAVIDEEMAKAGVPGPALSLH
MAV_1883|M.avium_104 AWVAAGKYGLIGFNMPEQYGGSGVDDFRFNAVIDEEIARYGGPAPALSLQ
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQG-ADSVAACIVIEEVARVDASASLIPAV
. *: . :**::** * * :: ** . :
Mb2743c|M.bovis_AF2122/97 NDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGITTR
Rv2724c|M.tuberculosis_H37Rv NDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGITTR
MMAR_1989|M.marinum_M NDIVAPYLLALATEEQKQRWLPKFCTGEFITAIAMTEPGTGSDLQGIKTR
MUL_3367|M.ulcerans_Agy99 NEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIKTR
MAB_3040c|M.abscessus_ATCC_199 NDVAGPYFRDLANDEQKARWFPGFCSGELISAIAMTEPGTGSDLQGIKTR
Mflv_2118|M.gilvum_PYR-GCK NDVVGPYFKDLTNDEQKKRWLPGVTSGETIIAVAMTEPGAGSDLAGIRTS
Mvan_4587|M.vanbaalenii_PYR-1 NDVVGPYFKDLTNDEQKKRWLPGIASGETIIAVAMTEPGAGSDLAGIRTS
MSMEG_5197|M.smegmatis_MC2_155 NDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAGIRTS
TH_4527|M.thermoresistible__bu NDVVAPYFNNLCTEEQKERWMPGIASGETIIAIAMTEPGAGSDLAGIRTS
MAV_1883|M.avium_104 NDVVGPYFSSLSNDEQKERWLPGITTGELIVAVAMTEPGAGSDLAGIRTS
MLBr_00737|M.leprae_Br4923 NKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTR
*.: : .:* : : :* . : : *::* :*** .: *
Mb2743c|M.bovis_AF2122/97 AVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERGM
Rv2724c|M.tuberculosis_H37Rv AVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERGM
MMAR_1989|M.marinum_M AVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVERGM
MUL_3367|M.ulcerans_Agy99 AVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVERGM
MAB_3040c|M.abscessus_ATCC_199 AVKDGDHYILNGAKTFITNGINADLVIVVAQTDPEKGALGFSLIVVERGM
Mflv_2118|M.gilvum_PYR-GCK AVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERDM
Mvan_4587|M.vanbaalenii_PYR-1 AVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERGM
MSMEG_5197|M.smegmatis_MC2_155 AVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERGM
TH_4527|M.thermoresistible__bu AVRDGDDWIINGSKTFISSGINCDLVVVVCRTDPEAGHKGFTLFVVERGM
MAV_1883|M.avium_104 AVRDGDDWIINGAKTFISSGINCDLVVVVCRTDPDAGHKGFTLFVVEAGM
MLBr_00737|M.leprae_Br4923 AKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKDD
* .**.:::** * :*:.* :. *:. ***: * *:: ::*. .
Mb2743c|M.bovis_AF2122/97 AGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQNLP
Rv2724c|M.tuberculosis_H37Rv AGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQNLP
MMAR_1989|M.marinum_M EGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQNLP
MUL_3367|M.ulcerans_Agy99 EGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQNLP
MAB_3040c|M.abscessus_ATCC_199 EGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFIYLMKNLP
Mflv_2118|M.gilvum_PYR-GCK EGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTNLP
Mvan_4587|M.vanbaalenii_PYR-1 EGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTNLP
MSMEG_5197|M.smegmatis_MC2_155 EGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLGKEGRGFYHLMTNLP
TH_4527|M.thermoresistible__bu EGFTRGRKLDKMGLHAQDTAELHFENVRVPHANLLGKEGHGFYHLMQNLP
MAV_1883|M.avium_104 DGFTRGRKLDKMGLHYQDTAELNFDNVRVPSANLLGKEGRGFYHLMHNLP
MLBr_00737|M.leprae_Br4923 EGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATLD
** * : .*:*:. . *:** * . :* .::*: * ** : .*
Mb2743c|M.bovis_AF2122/97 QERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELAT
Rv2724c|M.tuberculosis_H37Rv QERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELAT
MMAR_1989|M.marinum_M QERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAELAT
MUL_3367|M.ulcerans_Agy99 QERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAELAT
MAB_3040c|M.abscessus_ATCC_199 QERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFLLAELAT
Mflv_2118|M.gilvum_PYR-GCK SERLSIAISAIAGARAVFDETLQYSKDRKAFGQSIGSFQHNRFLLAEMET
Mvan_4587|M.vanbaalenii_PYR-1 SERLSIAISAIAGARAVFQETLQYAKDRKAFGQPIGSFQHNRFLLAEMET
MSMEG_5197|M.smegmatis_MC2_155 SERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFLLAEMET
TH_4527|M.thermoresistible__bu SERLSIAISAIAGARATWRETLQYAKDRKAFGKPIGSFQHNRFLLAEMDT
MAV_1883|M.avium_104 SERLSIAISAIAGARETWRQTLQYAKDRKAFGQPIGSFQHNRFMLAEMDT
MLBr_00737|M.leprae_Br4923 HTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAM
* :*. * . . . :: * .:** **..* .** :*:**::
Mb2743c|M.bovis_AF2122/97 EATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQLHG
Rv2724c|M.tuberculosis_H37Rv EATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQLHG
MMAR_1989|M.marinum_M EATMVRIMVDEFIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQLHG
MUL_3367|M.ulcerans_Agy99 EATMVRIMVDESIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQLHG
MAB_3040c|M.abscessus_ATCC_199 DATVIRVMVDEFISLLNKEE-LSVEQAAMAKWYSTEKQVHLIDRCLQLHG
Mflv_2118|M.gilvum_PYR-GCK ELEVTETYIDRCLQGVVDGE-LTAVEAAKAKWWATEVAKKVVDQCVQLHG
Mvan_4587|M.vanbaalenii_PYR-1 ELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKVVDQCVQLHG
MSMEG_5197|M.smegmatis_MC2_155 ELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKIVDNCVQLHG
TH_4527|M.thermoresistible__bu ELEVSEQYIDRCLQAVVDGE-LTAVEAAKAKWWCTEVAKKVVDQCVQLHG
MAV_1883|M.avium_104 ELEIGEQYIDRCLQAVVDGE-LTAVEAAKAKWWCTETAKKVIDGCVQLHG
MLBr_00737|M.leprae_Br4923 KVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLFG
. . : : :* :* :.:: : .:**.*
Mb2743c|M.bovis_AF2122/97 GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
Rv2724c|M.tuberculosis_H37Rv GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
MMAR_1989|M.marinum_M GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
MUL_3367|M.ulcerans_Agy99 GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
MAB_3040c|M.abscessus_ATCC_199 GYGFMREYPVARAYMDSRIQTIYGGTTEIMKEIIGRSL--
Mflv_2118|M.gilvum_PYR-GCK GYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV
Mvan_4587|M.vanbaalenii_PYR-1 GYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV
MSMEG_5197|M.smegmatis_MC2_155 GYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV
TH_4527|M.thermoresistible__bu GYGYMMEYRVARDFVDGRIQTIFGGTTEIMKEIIGRDLGL
MAV_1883|M.avium_104 GYGYMTEYRVARDYMDNRIMTIFGGTTEIMKDIIGRDLGL
MLBr_00737|M.leprae_Br4923 GAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
* *: :: * * * :: *: **.:* : ::.* *