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M. gilvum PYR-GCK Mflv_4558 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 4852742 - 4853923
length: 393

MRRVHYTDDHLAFGELARDFAAKAVAPHYEAWEDAGIIPRDVFTEAGALGLLGFAAPEQYGGVGTADFRY
NQILVERFMDAGCGGVGLSFAVHNDICLPYLADLTTPEQKKRWLPGFVSGRLIAAIGMTEPGAGSDLSGI
RTSAVDKGDHFLVNGAKTFITNGQNADLVITAVRTSPDRHRGLTLLVMERGLDGFERGRNLDKLGLHCQD
TSELTFTDVKVPKENVLGEVGDGFAHMMRNLAQERMQIAVGSLGRIRAALDWTVTYVRERTAFGKPIGAL
QNTRFSLADVATQLAVTQAFIDNCVIELNEGRLTAADAAMAKLWASETEFRCLDACQQLFGGYGYMREYP
IARAAIDARITRVYGGTSEIMREIIGRDLRLDRSPSAKEATHA

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. gilvum PYR-GCK Mflv_4558 - - 100% (393) acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK Mflv_2118 - e-112 51.05% (380) acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK Mflv_2446 - e-107 51.41% (389) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2743c fadE20 1e-110 51.72% (379) acyl-CoA dehydrogenase FADE20
M. tuberculosis H37Rv Rv2724c fadE20 1e-111 52.24% (379) acyl-CoA dehydrogenase FADE20
M. leprae Br4923 MLBr_00737 fadE25 1e-42 29.68% (374) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_3040c - 1e-110 51.72% (379) acyl-CoA dehydrogenase
M. marinum M MMAR_0697 - 1e-115 52.52% (377) acyl-CoA dehydrogenase
M. avium 104 MAV_4768 - 1e-121 54.76% (378) long-chain specific acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_5197 - 1e-113 51.05% (380) long-chain specific acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_3610 - 1e-114 53.25% (385) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_3367 fadE20 1e-109 51.72% (379) acyl-CoA dehydrogenase FadE20
M. vanbaalenii PYR-1 Mvan_2439 - 1e-113 53.97% (378) long-chain-acyl-CoA dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0697|M.marinum_M               ----------MTSRPEYTPEHHQFRQLVRDFVHRIVVPAHEPGERRGQWD
MAV_4768|M.avium_104                ----------MAAHLQYTSEHHQFRELVRDFVQRTVVPNHEKWERDGQWD
Mb2743c|M.bovis_AF2122/97           MGS-----ATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVD
Rv2724c|M.tuberculosis_H37Rv        MGS-----ATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVD
MUL_3367|M.ulcerans_Agy99           MGS-----AIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVD
Mvan_2439|M.vanbaalenii_PYR-1       MGASEAKPVIAYERTLFEPEHDMFRESFRAFLDRHVAPHHEEWEKNKLVD
MAB_3040c|M.abscessus_ATCC_199      MAG-----AVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVD
MSMEG_5197|M.smegmatis_MC2_155      -----------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVD
Mflv_4558|M.gilvum_PYR-GCK          -----------MRRVHYTDDHLAFGELARDFAAKAVAPHYEAWEDAGIIP
TH_3610|M.thermoresistible__bu      -----------VRREVFTDDHEAFRELARDFIEKEVVPNYPDWEKAGRMP
MLBr_00737|M.leprae_Br4923          --MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFP
                                                       :*  :    :    :         :      

MMAR_0697|M.marinum_M               RALFTEAARLGLLGFSVPERFGGPGVNDFRYNAIVIDELQRAGAASEAIA
MAV_4768|M.avium_104                RSLFVEAGKLGLLGFSVPERLGGPGVDDFRYNAIVVDELQRAGAAAEAIA
Mb2743c|M.bovis_AF2122/97           RGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAG--RYSGIG
Rv2724c|M.tuberculosis_H37Rv        RGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAG--RYSGIG
MUL_3367|M.ulcerans_Agy99           RGVWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAG--RYSGIG
Mvan_2439|M.vanbaalenii_PYR-1       RDVWLEAGKQGFLGMAVPEEYGGGGVDDFRYNTIVTEEVTAG--RYTGLG
MAB_3040c|M.abscessus_ATCC_199      RALWVEAGKQGFLGTDMPEEFGGGGLIDFRYNTIITEEVTKG--RHTGVG
MSMEG_5197|M.smegmatis_MC2_155      RSAYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIAKS--GVHGPA
Mflv_4558|M.gilvum_PYR-GCK          RDVFTEAGALGLLGFAAPEQYGGVGTADFRYNQILVERFMDAGCGGVGLS
TH_3610|M.thermoresistible__bu      REAFELMGSLGMLGMAIPEQYGGAGIVDYRYNVVLQEEAARA--LVTLST
MLBr_00737|M.leprae_Br4923          EEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD---ASASL
                                    .         *: .   **. ** *  .     :: :             

MMAR_0697|M.marinum_M               FTLQNDVVLPYLTDLTTLEQQQRWLPGVVTGDTVLGIAMTEPGAGSDLAG
MAV_4768|M.avium_104                FSLQNDIVLPYLVELTTPEQQRRWLPGVVTGETVLGIAMTEPGTGSDLAG
Mb2743c|M.bovis_AF2122/97           FGLHNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQG
Rv2724c|M.tuberculosis_H37Rv        FGLHNDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQG
MUL_3367|M.ulcerans_Agy99           FGLHNEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQG
Mvan_2439|M.vanbaalenii_PYR-1       FSLHNDVAAPYLIRLATEEQKQRWLPKFCSGEIISAIAMTEPGTGSDLQG
MAB_3040c|M.abscessus_ATCC_199      FSLHNDVAGPYFRDLANDEQKARWFPGFCSGELISAIAMTEPGTGSDLQG
MSMEG_5197|M.smegmatis_MC2_155      LSLHNDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAG
Mflv_4558|M.gilvum_PYR-GCK          FAVHNDICLPYLADLTTPEQKKRWLPGFVSGRLIAAIGMTEPGAGSDLSG
TH_3610|M.thermoresistible__bu      VRTQLDVILPYFLHYADEEQRARWFPGLAAGKLLTAIAMTEPGTGSDLAG
MLBr_00737|M.leprae_Br4923          IPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAAS
                                    .    .:    :      * : : :* . :     . .::*  :***  .

MMAR_0697|M.marinum_M               IHTTAVRDGSHYVVNGAKTFISNGQSGDLFVIAVRT--SPER-HQGLSLL
MAV_4768|M.avium_104                IRTTAVRDGDHYLVNGAKTFISNGQVGDLFVVAVRT--APDR-HKGLSLL
Mb2743c|M.bovis_AF2122/97           ITTRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQT--DPEKGAQGFSLL
Rv2724c|M.tuberculosis_H37Rv        ITTRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQT--DPEKGAQGFSLL
MUL_3367|M.ulcerans_Agy99           IKTRAVKQGDHYLLNGSKTFITNGINADLVIVVAQT--DPEKGAQGFSLL
Mvan_2439|M.vanbaalenii_PYR-1       IKTRAVRDGDHYVLNGAKTFITNGIHSDLVIVVAQT--DPDKGALGFSLL
MAB_3040c|M.abscessus_ATCC_199      IKTRAVKDGDHYILNGAKTFITNGINADLVIVVAQT--DPEKGALGFSLI
MSMEG_5197|M.smegmatis_MC2_155      IRTSAVRDGDDWIINGSKTFISSGINCDLCVVVART--DPEAGHKGFSLF
Mflv_4558|M.gilvum_PYR-GCK          IRTSAVDKGDHFLVNGAKTFITNGQNADLVITAVRT--SPDR-HRGLTLL
TH_3610|M.thermoresistible__bu      VRTTAVRDGDDYILNGAKTFITGGIQADLVIVVARTSTDPDNRRRGLTLL
MLBr_00737|M.leprae_Br4923          MRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVT--DPDKGANGISAF
                                    : * *  .*..:::** * :*:.*         . *   *:    *:: :

MMAR_0697|M.marinum_M               VVDATTPGFHRGRSLEKIGLHAQDTSELSFTDMRVPVENLLQNEGMGFYQ
MAV_4768|M.avium_104                VVDADTPGFGRGRNLEKIGLHAQDTSELSFTDMRVPAENLLEAEGRGFYQ
Mb2743c|M.bovis_AF2122/97           VVERGMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIY
Rv2724c|M.tuberculosis_H37Rv        VVERGMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIY
MUL_3367|M.ulcerans_Agy99           VVERGMEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIY
Mvan_2439|M.vanbaalenii_PYR-1       VVERGMAGFERGRKLDKIGLDAQDTAELSFTDVKVPVENLLGEEGQGFIY
MAB_3040c|M.abscessus_ATCC_199      VVERGMEGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFIY
MSMEG_5197|M.smegmatis_MC2_155      VVERGMEGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLGKEGRGFYH
Mflv_4558|M.gilvum_PYR-GCK          VMERGLDGFERGRNLDKLGLHCQDTSELTFTDVKVPKENVLGEVGDGFAH
TH_3610|M.thermoresistible__bu      VVEDGMPGFTRGRELEKMGCKVQDTAELSFTDVRVPVANRLGEEGEAFSY
MLBr_00737|M.leprae_Br4923          IVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKT
                                    ::.    **  *   .*:* . . *:** * .  :*  . :   * .*  

MMAR_0697|M.marinum_M               LMRNLPQERLALAVGAVAAAEGILAETLDYVRQRKAFGSPIASFQHSQFL
MAV_4768|M.avium_104                LMKNLPQERLSLAVGAVAAAEAVFAETLDYVKQRHAFGAPIAAFQNSQFV
Mb2743c|M.bovis_AF2122/97           LMQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFL
Rv2724c|M.tuberculosis_H37Rv        LMQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFL
MUL_3367|M.ulcerans_Agy99           LMQNLPQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFV
Mvan_2439|M.vanbaalenii_PYR-1       LMQNLPQERISIAIMAAAAMEAVLDVTLQYTKERKAFGRPIGSQQNSRFL
MAB_3040c|M.abscessus_ATCC_199      LMKNLPQERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFL
MSMEG_5197|M.smegmatis_MC2_155      LMTNLPSERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFL
Mflv_4558|M.gilvum_PYR-GCK          MMRNLAQERMQIAVGSLGRIRAALDWTVTYVRERTAFGKPIGALQNTRFS
TH_3610|M.thermoresistible__bu      LGHNLAQERMTVAVGSVAQARSAIDTTIEYVKSRKAFGTPVASFQNTKFE
MLBr_00737|M.leprae_Br4923          ALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFM
                                       .*   *  :.  : .  .. :  :: *  .*  ** .:   *  :* 

MMAR_0697|M.marinum_M               LAELATEIDIARTYLDDCLAQHLAGE-LTAARAARLKWWTTELQVRTADR
MAV_4768|M.avium_104                LAELATEIDVARTYLDDCLAAHLTGE-LTAARAARLKWWTTDLQVRTADR
Mb2743c|M.bovis_AF2122/97           LAELATEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDR
Rv2724c|M.tuberculosis_H37Rv        LAELATEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDR
MUL_3367|M.ulcerans_Agy99           LAELATEATMVRIMVDESIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDR
Mvan_2439|M.vanbaalenii_PYR-1       LAELSTEATVVRMMVDEFIKLHLQDK-LTVEQAAMAKWYSTEKQVHLIDR
MAB_3040c|M.abscessus_ATCC_199      LAELATDATVIRVMVDEFISLLNKEE-LSVEQAAMAKWYSTEKQVHLIDR
MSMEG_5197|M.smegmatis_MC2_155      LAEMETELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKIVDN
Mflv_4558|M.gilvum_PYR-GCK          LADVATQLAVTQAFIDNCVIELNEGR-LTAADAAMAKLWASETEFRCLDA
TH_3610|M.thermoresistible__bu      LAACSAEVEAAQAMLDRAVLDLVDGQ-LSGADAARVKLFCTEMQARVVDR
MLBr_00737|M.leprae_Br4923          LADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTD
                                    **    .    .  :          .      :*  * : ::        

MMAR_0697|M.marinum_M               CLQLHGGYGYMREYRVSQAFVDARIQTIYGGTNEIMKTIIAKDLGI----
MAV_4768|M.avium_104                CLQLHGGYGYMREYGVARAFVDARIQTIYGGTNEIMKTIIAKDLGL----
Mb2743c|M.bovis_AF2122/97           CLQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV----
Rv2724c|M.tuberculosis_H37Rv        CLQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV----
MUL_3367|M.ulcerans_Agy99           CLQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI----
Mvan_2439|M.vanbaalenii_PYR-1       CLQLHGGYGYMREYDVARAYLDARVQTIYGGTTEIMKEIIGRSLGV----
MAB_3040c|M.abscessus_ATCC_199      CLQLHGGYGFMREYPVARAYMDSRIQTIYGGTTEIMKEIIGRSL------
MSMEG_5197|M.smegmatis_MC2_155      CVQLHGGYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV----
Mflv_4558|M.gilvum_PYR-GCK          CQQLFGGYGYMREYPIARAAIDARITRVYGGTSEIMREIIGRDLRLDRSP
TH_3610|M.thermoresistible__bu      CLQLFGGYGYMMEYPIARLYTDARVARIYAGTSEVMKVIIAKSLGL----
MLBr_00737|M.leprae_Br4923          AVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR----
                                    . **.** *:  :: : :   *.::  :: **.:: : ::.: *      

MMAR_0697|M.marinum_M               --------
MAV_4768|M.avium_104                --------
Mb2743c|M.bovis_AF2122/97           --------
Rv2724c|M.tuberculosis_H37Rv        --------
MUL_3367|M.ulcerans_Agy99           --------
Mvan_2439|M.vanbaalenii_PYR-1       --------
MAB_3040c|M.abscessus_ATCC_199      --------
MSMEG_5197|M.smegmatis_MC2_155      --------
Mflv_4558|M.gilvum_PYR-GCK          SAKEATHA
TH_3610|M.thermoresistible__bu      --------
MLBr_00737|M.leprae_Br4923          --------

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_4558	-	-	100% (393)	acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK	Mflv_2118	-	e-112	51.05% (380)	acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK	Mflv_2446	-	e-107	51.41% (389)	acyl-CoA dehydrogenase domain-containing protein