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ARACPLVIIAAVLGLTVLAAGGGRAAAAPGQDDHGAPVIPPPAFPALPLPVLSIPAGLPPFPYPADVPVV QLPADIPTVEFPSAVPPVTLPGPVPSVQLPAAIPPIQLPAPIPRGLL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1992 | - | - | 100% (118) | hypothetical protein Mflv_1992 |
| M. gilvum PYR-GCK | Mflv_1703 | - | 6e-09 | 37.80% (82) | transglycosylase domain-containing protein |
| M. gilvum PYR-GCK | Mflv_3300 | - | 5e-06 | 35.87% (92) | hypothetical protein Mflv_3300 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2188c | - | 3e-07 | 33.05% (118) | hypothetical protein Mb2188c |
| M. tuberculosis H37Rv | Rv2164c | - | 3e-07 | 33.05% (118) | hypothetical protein Rv2164c |
| M. leprae Br4923 | MLBr_00568 | - | 9e-06 | 35.35% (99) | hypothetical protein MLBr_00568 |
| M. abscessus ATCC 19977 | MAB_4537c | - | 7e-07 | 40.48% (84) | hypothetical protein MAB_4537c |
| M. marinum M | MMAR_0602 | - | 3e-10 | 40.74% (81) | hypothetical protein MMAR_0602 |
| M. avium 104 | MAV_4824 | - | 5e-09 | 31.30% (115) | hypothetical protein MAV_4824 |
| M. smegmatis MC2 155 | MSMEG_3315 | - | 3e-16 | 47.89% (71) | hypothetical protein MSMEG_3315 |
| M. thermoresistible (build 8) | TH_1738 | - | 8e-07 | 38.82% (85) | MCE-FAMILY PROTEIN MCE4F |
| M. ulcerans Agy99 | MUL_1725 | secD | 2e-06 | 34.38% (96) | preprotein translocase subunit SecD |
| M. vanbaalenii PYR-1 | Mvan_3343 | - | 1e-08 | 35.78% (109) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1992|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0602|M.marinum_M --------------------------------------------------
MAV_4824|M.avium_104 --------------------------------------------------
MSMEG_3315|M.smegmatis_MC2_155 --------------------------------------------------
Mb2188c|M.bovis_AF2122/97 --------------------------------------------------
Rv2164c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_00568|M.leprae_Br4923 --------------------------------------------------
MUL_1725|M.ulcerans_Agy99 MASSSAPVHPARYLSVFLVLLIGVYLLVFLTGDKKAAPKLGIDLQGGTRV
MAB_4537c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1738|M.thermoresistible__bu --------------------------------------------------
Mflv_1992|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0602|M.marinum_M ----------------------------------------------MVEQ
MAV_4824|M.avium_104 --------------------------------------------------
MSMEG_3315|M.smegmatis_MC2_155 --------------------------------------------------
Mb2188c|M.bovis_AF2122/97 --------------------------------------------------
Rv2164c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_00568|M.leprae_Br4923 --------------------------------------------------
MUL_1725|M.ulcerans_Agy99 TLTARTPDGSAPSREALAQAQQIISARVNGLGVSGSEVVVDGDNLVITVP
MAB_4537c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1738|M.thermoresistible__bu --------------MLSRLVRMQLAVFTAVALISVLAIAVFYIQVPKTLG
Mflv_1992|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0602|M.marinum_M VLGELLDTVLGVSVAPTAVRLVLVEGENGDGALVDEDAFDVSGDGDAATI
MAV_4824|M.avium_104 -----MDTVLGVSMAPTAVRMVLVEGENGDGATVDEDNFDVATSEDAATV
MSMEG_3315|M.smegmatis_MC2_155 --------------------------------------------------
Mb2188c|M.bovis_AF2122/97 ----------------------MRAKREAPKSRSSDRRRRADSPAAATRR
Rv2164c|M.tuberculosis_H37Rv ----------------------MRAKREAPKSRSSDRRRRADSPAAATRR
Mvan_3343|M.vanbaalenii_PYR-1 ----------------------------------MRVRRKMSPSMNRISV
MLBr_00568|M.leprae_Br4923 --------------------------------------------------
MUL_1725|M.ulcerans_Agy99 GNDGNEARNLGQTARLYIRPVMNSMPAQPAAQEPQQEPQQPGGTAPAPGG
MAB_4537c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1738|M.thermoresistible__bu FGSYRVTADFAGSGGIYPNANVAYRGTTIGKVTGVSLTHDNDVRVEMRID
Mflv_1992|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0602|M.marinum_M GAAEQVISAILGTREGASEGGYQLTSTGVTWRDPAQAAALRDVLARRKIE
MAV_4824|M.avium_104 TASDQVLSAILGTRQGAAEGGYQLASTGVTFTDPVEAAALRDKLAAHKVE
MSMEG_3315|M.smegmatis_MC2_155 --------------------------------------------------
Mb2188c|M.bovis_AF2122/97 TTTNSAPSRRIRSRAGKTSAPGRQARVSRPGPQTSPMLSPFDRPAPAKNT
Rv2164c|M.tuberculosis_H37Rv TTTNSAPSRRIRSRAGKTSAPGRQARVSRPGPQTSPMLSPFDRPAPAKNT
Mvan_3343|M.vanbaalenii_PYR-1 TTLAALGMVWPFLFYGAPAAAEPSPGVPCLEILQQLAAAPPSVPETLDTA
MLBr_00568|M.leprae_Br4923 --------------------------------------------------
MUL_1725|M.ulcerans_Agy99 PAPNAGQPPESSAPASPQSGAPAAPQSGTPGRPGAQPRPYPQDPPPSPAP
MAB_4537c|M.abscessus_ATCC_199 --------MLVLTRWFRRALVSGVCVAGLLGAGVVPALADPGDPPDPGIE
TH_1738|M.thermoresistible__bu DDRKVPANVNAYVKSMSAIGEQYVDLVPPEHASTESLRGGSHIGRDRTFI
Mflv_1992|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0602|M.marinum_M NVVLVSAFLAAAALAHAVGSETNYAQTALLFIEPEAATLAVVDSADGSVT
MAV_4824|M.avium_104 NVMLVSAFLAAAALAQAVGHRTNYAHTALLYIEPDTATLAVVDSADGSIA
MSMEG_3315|M.smegmatis_MC2_155 --------------------------------------------------
Mb2188c|M.bovis_AF2122/97 SQAKARAKARKAKAPKLVRPTP---------MERLAARLTSIDLRPRTLA
Rv2164c|M.tuberculosis_H37Rv SQAKARAKARKAKAPKLVRPTP---------MERLAARLTSIDLRPRTLA
Mvan_3343|M.vanbaalenii_PYR-1 ANALNNVVPEAAPALPPVPVAEVVHGLTALAAPGPVPPVDAAPLAAPPVP
MLBr_00568|M.leprae_Br4923 --------------------------------------------------
MUL_1725|M.ulcerans_Agy99 APSPAPTGSPAPPATGAQQPADLPPGEEPALPDPRKDLAERIAQEKKWRQ
MAB_4537c|M.abscessus_ATCC_199 EPGPP---------------------------PPPPLPWELPPPPPPPAP
TH_1738|M.thermoresistible__bu NGDIAGMLREAQALVDSLDRSRLRDVLKETFAAFNGSGPELARLLESSRL
Mflv_1992|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0602|M.marinum_M DIHRLSLSDDDDTAVGQLTELISQAESLPTRPDAVFLVGSGIDLPLIKPT
MAV_4824|M.avium_104 DVRRQPLPEDDEAAVAELASMVSNAENLETRPDAVFVVGSGIDIPLIKPA
MSMEG_3315|M.smegmatis_MC2_155 --------------------------------------------------
Mb2188c|M.bovis_AF2122/97 NKVPFVVLVIGSLGVGLGLTLWLSTDAAERSYQLSNARERTRMLQQHKEA
Rv2164c|M.tuberculosis_H37Rv NKVPFVVLVIGSLGVGLGLTLWLSTDAAERSYQLSNARERTRMLQQHKEA
Mvan_3343|M.vanbaalenii_PYR-1 PVDAAPLAAPLVQAAAGPVPAAAPIPVVAPPIPAVIPLAPPVPVVAPPPA
MLBr_00568|M.leprae_Br4923 ----------------------------------------MKVFDRFNTA
MUL_1725|M.ulcerans_Agy99 STNQYIQMVALQFEATQCGKDDILAGNDDPKLPLVTCSTDHKTAYLLAPS
MAB_4537c|M.abscessus_ATCC_199 DAPPPAEVPPVPAPVPTTPPPGAPPTGDVPPLPVGLLKNSPNNGDVVGVA
TH_1738|M.thermoresistible__bu LVEEAGDATDDTIGLVEQSQPLLDAQVTAGDDIRAVADGLARLTSHLREA
Mflv_1992|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0602|M.marinum_M LEASTTLPVTAAEEPDTALARGAALAAASSPLFASSTAAQAWAQDPGSGV
MAV_4824|M.avium_104 LEAATTLPLTAPEEPDTALARGAALASAHAPLFASSTAALAYAQDPGTGA
MSMEG_3315|M.smegmatis_MC2_155 --------------------------------------------------
Mb2188c|M.bovis_AF2122/97 LERDVREAASAPALAEAARRQGMIPTRDTAHLAQDPDGNWVVVGTPKP--
Rv2164c|M.tuberculosis_H37Rv LERDVREAASAPALAEAARRQGMIPTRDTAHLVQDPDGNWVVVGTPKP--
Mvan_3343|M.vanbaalenii_PYR-1 VPVAAPVEAVLASAPEPVAPAPVPPAPGEAAPVELAAAPPPVEPAPPAPP
MLBr_00568|M.leprae_Br4923 ILVSAGLCGAALAFSPSAAAAPLSMPTGGPTCIEQMAG------------
MUL_1725|M.ulcerans_Agy99 IISGDQIQNATSGMDQRSIGYVVDLQFKSQAANTWADYTAAHIGTQTAFT
MAB_4537c|M.abscessus_ATCC_199 QPITIVFAAPVTDKKAAEAAVKITTSKPAPGYFYWYTDQQLRWKPTQFWP
TH_1738|M.thermoresistible__bu DPQFREVLQKAPAAADQATTLFDGIRPTFPVLAANLANAGRIGVIYHKSI
Mflv_1992|M.gilvum_PYR-GCK -------------------------------------------------M
MMAR_0602|M.marinum_M LY----------SHAPYGLDAAYFDDVSDQLG---TGQQALAYSAVPEEQ
MAV_4824|M.avium_104 INPLAVAPGYFETPADAGADGLAYSAVPDDPDEFFTGTQAAATELVDADY
MSMEG_3315|M.smegmatis_MC2_155 --------------------------------------------------
Mb2188c|M.bovis_AF2122/97 -------------------------------------ADGVPPPPLNTKL
Rv2164c|M.tuberculosis_H37Rv -------------------------------------ADGVPPPPLNTKL
Mvan_3343|M.vanbaalenii_PYR-1 EP-----------------------------------PPTAPTDVAPAVA
MLBr_00568|M.leprae_Br4923 ------------------------------------------LGAVPAAV
MUL_1725|M.ulcerans_Agy99 LDSQVVSAPQILEAIPGGRTQISGGEPPFSASTARQLANVLKYGSLPLSF
MAB_4537c|M.abscessus_ATCC_199 AN------------------------------------TDVNVNAGGTKW
TH_1738|M.thermoresistible__bu EQVLVIIPAVTAAIIAIANQFPADEGAKGDFKLNFGDPPPCITGFVPPSE
Mflv_1992|M.gilvum_PYR-GCK ARACPLVIIA-------------AVLGLTVLAAGGGRAAAAPGQDDHGAP
MMAR_0602|M.marinum_M HERRPFALLASIMGSIFIIGVGALAVSLAVSIRSEPGTRPDPGQSVVTHL
MAV_4824|M.avium_104 ADRSSFKLVGSAVAAIFVIGVVALVVSLAIAIRPTANVRPSPNQNVVVAP
MSMEG_3315|M.smegmatis_MC2_155 -----------------------MTLVVGVLISG-AGCAPDGDR------
Mb2188c|M.bovis_AF2122/97 PEDPPPPPKP-----------AAVPLEVPVRVTPGPDDPAPPARSGPEVL
Rv2164c|M.tuberculosis_H37Rv PEDPPPPPKP-----------AAVPLEVPVRVTPGPDDPAPPARSGPEVL
Mvan_3343|M.vanbaalenii_PYR-1 EPVAPEPVMAP---------AAAEPTPAAVAPVEPGPAPVELVAAAEPAP
MLBr_00568|M.leprae_Br4923 PAVLPGPVAG---------------AVPSVPVVPSGGFPPVVPPGGFPPV
MUL_1725|M.ulcerans_Agy99 ESSEAQTVSATLGLTSLRAGLIAGAIGLALVLLYSLLYYRVLGLLTALSL
MAB_4537c|M.abscessus_ATCC_199 SFKVGDAFVST---------VDDATYTMTVTRNGVVERTMPISMGKHDKK
TH_1738|M.thermoresistible__bu IRSPADTTLRDVPKELYCKVPHNDPAVVRGARNYPCMEFPGKRAATVQQC
Mflv_1992|M.gilvum_PYR-GCK VIPPPAFPALP------------------LPVLSIPAGLPPFPYP-----
MMAR_0602|M.marinum_M PAPAHAAPAPQPQAPAPQAPAPQAQAPAPQAQVPAPAPAPQAPAPRAPAP
MAV_4824|M.avium_104 TRPAPAAPAP---------------APAPEAPAPAPAAAPQAPAP-----
MSMEG_3315|M.smegmatis_MC2_155 ----SATPEN------------------PVTTLPVPPNIPPFPLP-----
Mb2188c|M.bovis_AF2122/97 VRTPDGTATLG------------------GATHLPTQAGPQLPGP-----
Rv2164c|M.tuberculosis_H37Rv VRTPDGTATLG------------------GATHLPTQAGPQLPGP-----
Mvan_3343|M.vanbaalenii_PYR-1 IMEPAAAPVES------------------APVFHAAAVPPALPGP-----
MLBr_00568|M.leprae_Br4923 VPPGGFLPVVP--------------------PGGFPPVVPPGGFP-----
MUL_1725|M.ulcerans_Agy99 IASGAMVFAILVLLG--------RYINYTLDLAGIAGLIIGIGTTADSFV
MAB_4537c|M.abscessus_ATCC_199 HETKNGTYYVS------------------EKFQKMVMDSSTYGVP-----
TH_1738|M.thermoresistible__bu RDPEGYVPIGSNPWR------------GPPVPVGTPITDPRMILP-----
.
Mflv_1992|M.gilvum_PYR-GCK --------ADVPVVQLPADIPTVEFPSAVPPVTLPGPV---------PSV
MMAR_0602|M.marinum_M QAPAPQAQVPAPKAPAPVPVPVAQAPVPVPQAPAPVPVPIPQAPAPAPEA
MAV_4824|M.avium_104 ---APEAPAPAPAAPAPAPVQVA--PVPVPEAPAPAPA--------APPP
MSMEG_3315|M.smegmatis_MC2_155 --------DAIPVVPLPDAVPAVEMPNDIPRVQAPADV---------PKM
Mb2188c|M.bovis_AF2122/97 --------VPIPGAPGPMPAPPLGAVPSPAPAENPVPL--------QVGA
Rv2164c|M.tuberculosis_H37Rv --------VPIPGAPGPMPAPPLGAVPSPAPAENPVPL--------QVGA
Mvan_3343|M.vanbaalenii_PYR-1 ---------VVPVVPAGVPVPVAPVGVPVPVVPTGAPAAVPAPPLGLPAV
MLBr_00568|M.leprae_Br4923 --------PVVPPGVAPAVGPLLAEDSAALGSGILAGKG-------VPTA
MUL_1725|M.ulcerans_Agy99 VFFERIKDEIREGRSFRSAVPRGWARARKTIVSGNAVTFLAAAVLYFLAI
MAB_4537c|M.abscessus_ATCC_199 -------VNSAEGYKLDVYWATRLSNSGIFVHAAPWSVG---------AQ
TH_1738|M.thermoresistible__bu ---QNKYPYIPPQADYDPGPPVVQLPPGVPPGPGPALTP-PYPTQIPPVT
Mflv_1992|M.gilvum_PYR-GCK QLPAAIP-PIQLPAPIPRGLL-----------------------------
MMAR_0602|M.marinum_M PVPAPVPIPVPIQIPLPQIFGPGGGGGFPGGDDDRGGRGGG--RGGRHGG
MAV_4824|M.avium_104 PPPAVAPIPVPIPLPIPGLGGPGFGGPPGHGGGDGGGHGGGGFPGFPGGG
MSMEG_3315|M.smegmatis_MC2_155 QLPSDIP-PVPLPSAIPPIVFP----------------------------
Mb2188c|M.bovis_AF2122/97 APPAGLPGPAPVAATPGLSGGSQPMVAPPAPVPANGEQFGPVTAPVPTAP
Rv2164c|M.tuberculosis_H37Rv APPAGLPGPAPVAATPGLSGGSQPMVAPPAPVPANGEQFGPVTAPVPTAP
Mvan_3343|M.vanbaalenii_PYR-1 PLGDAVPGVPFLPATLPIPQDLVCEGTAWSAGRTAPEGDAAALDAPPGQR
MLBr_00568|M.leprae_Br4923 SPQAALSGLVVLPGPPASVEAPPAAAPVVAAATPLLCCGEAAPPVR----
MUL_1725|M.ulcerans_Agy99 GQVKGFAFTLGLTTILDIVVVFLVTWPLVYLASKSPRLAKPAYNGLGAVQ
MAB_4537c|M.abscessus_ATCC_199 GKSDTSHGCINVNTDNATWFFNQSHPGDPVIVKNSPGGPYKDYDGYDDWQ
TH_1738|M.thermoresistible__bu PGPPPPPLPFQPPPDQIVPPYGRPPAPPPPAEGDRPQAAGVDVATYDPAT
Mflv_1992|M.gilvum_PYR-GCK ----------------------------------------
MMAR_0602|M.marinum_M GHGGG--HGRGGFNIPFIPGI-------------------
MAV_4824|M.avium_104 GHGGGGFPGFGGGHGGFGHH--------------------
MSMEG_3315|M.smegmatis_MC2_155 ----------------------------------------
Mb2188c|M.bovis_AF2122/97 GAPR------------------------------------
Rv2164c|M.tuberculosis_H37Rv GAPR------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 RDQW------------------------------------
MLBr_00568|M.leprae_Br4923 ----------------------------------------
MUL_1725|M.ulcerans_Agy99 QVARERRASDSRTRSGIAKTGRE-----------------
MAB_4537c|M.abscessus_ATCC_199 RF--------------------------------------
TH_1738|M.thermoresistible__bu GKFLDPHTGISVYASGIAAPSIAENWVDLMTYPRTGSEPA