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MSAAAAKLSIATPVVTLLPGVSAPWEKTASIEDLTQIAETADKLGYYHLTCSEHIALPAAEKRRRGTRYW DPLATLGYLAARTQRIRLATNVLVLGYHHPLEIAKRYGTLDTVSNGRLILGVGVGSLKEEFDLIGAPFED RGARADDALRALRAALSVPEPRYHGEFYSFRDMVVDPCAVQKRLPIWVGGRTLRSLRRATSLAEGWVPFG ISLGEARDWLSRFDIGSGFEVVLSSPEPLNPIGDPERTRHLLADLAAHGATTICATFAHSSRQQYLDNLH ALAELDSP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3440 | - | - | 100% (288) | hypothetical protein MMAR_3440 |
| M. marinum M | MMAR_1586 | - | 1e-26 | 34.95% (206) | oxidoreductase |
| M. marinum M | MMAR_0393 | - | 3e-26 | 35.16% (182) | hypothetical protein MMAR_0393 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | 5e-20 | 29.34% (242) | hypothetical protein Mb0815c |
| M. gilvum PYR-GCK | Mflv_4544 | - | 7e-88 | 58.70% (276) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0791c | - | 5e-20 | 29.34% (242) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00348 | - | 2e-07 | 26.62% (154) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 3e-28 | 36.54% (208) | hypothetical protein MAB_0366 |
| M. avium 104 | MAV_3045 | - | 1e-33 | 33.33% (204) | hypothetical protein MAV_3045 |
| M. smegmatis MC2 155 | MSMEG_2896 | - | 3e-87 | 56.83% (278) | hypothetical protein MSMEG_2896 |
| M. thermoresistible (build 8) | TH_3565 | - | 4e-89 | 55.20% (279) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_2716 | - | 1e-165 | 99.31% (288) | hypothetical protein MUL_2716 |
| M. vanbaalenii PYR-1 | Mvan_3368 | - | 8e-88 | 57.97% (276) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0815c|M.bovis_AF2122/97 ------------MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEY
Rv0791c|M.tuberculosis_H37Rv ------------MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEY
MMAR_3440|M.marinum_M ------MSAAAAKLSIATPVVTLLPGVSAPWEKTASIEDLTQIAETADKL
MUL_2716|M.ulcerans_Agy99 MLASIAMSAAAAKLSIATPVVTLLPGVSAPWEKTASIEDLTQIAETADKL
Mflv_4544|M.gilvum_PYR-GCK -----------MRIGLSTPVVVQTPAAASPWEAGAGIGDIARIAETADDL
Mvan_3368|M.vanbaalenii_PYR-1 ---------------MSTPVVVQTPAMASPWEGGADIEDVARIAEVADSL
TH_3565|M.thermoresistible__bu -----------MRIGISTPVVMQMPGVASDWERTAGPDELARVAAAADDL
MSMEG_2896|M.smegmatis_MC2_155 -------------MGLSTPVVVQVPQVASAWEATATVDDLVAIAQAADET
MAB_0366|M.abscessus_ATCC_1997 --------------------MKIGVVAPVELGVTAEPDKILEFARAAERL
MAV_3045|M.avium_104 -----------MKFAFPVPHLMRLKAIAQPWEAAVTGPEQRRMMQCADRW
MLBr_00348|M.leprae_Br4923 ---------------MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGA
. . *:
Mb0815c|M.bovis_AF2122/97 GFDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLP
Rv0791c|M.tuberculosis_H37Rv GFDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLP
MMAR_3440|M.marinum_M GYYHLTCSEHIALPAAE--------------------------KRRRGTR
MUL_2716|M.ulcerans_Agy99 GYYHLTCSEHIALPAAE--------------------------KRRRGTR
Mflv_4544|M.gilvum_PYR-GCK GFDYLTCSEHVAVPVGD--------------------------AAVRGAT
Mvan_3368|M.vanbaalenii_PYR-1 GFDYLTCSEHVAVPVDE--------------------------AGLRGAV
TH_3565|M.thermoresistible__bu GFEFLTCAEHVVVPEAD--------------------------AAVRGAT
MSMEG_2896|M.smegmatis_MC2_155 GFDFLTCSEHVAIPRAD--------------------------AARRGAV
MAB_0366|M.abscessus_ATCC_1997 GFSEISVVEHAVVIGDTQSTYPYSPTG--------------QSHLPDDID
MAV_3045|M.avium_104 GYDMIAVPEHLVIPVDQ--------------------------VELSGSH
MLBr_00348|M.leprae_Br4923 GFDAVFTGEAWGS-------------------------------------
*: : :
Mb0815c|M.bovis_AF2122/97 LLECWTALAALSRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQGRL
Rv0791c|M.tuberculosis_H37Rv LLECWTALAALSRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQGRL
MMAR_3440|M.marinum_M YWDPLATLGYLAARTQRIRLATNVLVLGYHHPLEIAKRYGTLDTVSNGRL
MUL_2716|M.ulcerans_Agy99 YWDPLATLSYLAARTQRIRLATNVLVLGYHHPLEIAKRYGTLDTVSNGRL
Mflv_4544|M.gilvum_PYR-GCK YWDPLATLGFLAARTARIRLATSVLVLGYHHPLEIAKRYGTLDRVSGGRL
Mvan_3368|M.vanbaalenii_PYR-1 YWDPLATLGFLAARTSRIRLATSVLVLGYHHPLEIAKRYGTLDRVSGGRL
TH_3565|M.thermoresistible__bu YWDPVATLGFLAAHTTRIRLATSVIVLGYHHPLEVAKRYGTVDRLSGGRV
MSMEG_2896|M.smegmatis_MC2_155 YWDPLSTLGFLAAHTRRIRLATAVLVLSYHHPLELVKRYGTLDRLSCGRL
MAB_0366|M.abscessus_ATCC_1997 IPDPLELLSFVAAATTTLGLSTGVLVLPDHHPVVLAKRLATLDRLSRGRL
MAV_3045|M.avium_104 YLHSTTAQAFIAGATERVAINSCVTILPLQHPIVLAKALATADWMSGGRM
MLBr_00348|M.leprae_Br4923 --DAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRH
. . . * : : : * : * . * * :* **
Mb0815c|M.bovis_AF2122/97 DLGLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTEPNPT-YA
Rv0791c|M.tuberculosis_H37Rv DLGLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTEPNPT-YA
MMAR_3440|M.marinum_M ILGVGVGSLKEEFDLIGAPFE---DRGARADDALRALRAALSVPEPR-YH
MUL_2716|M.ulcerans_Agy99 ILGVGVGSLKEEFDLIGAPFE---NRGARADDALRALRAALSVPEPR-YH
Mflv_4544|M.gilvum_PYR-GCK ILGVGVGSLQPEFDLLGAPWE---ERGARADDAIRALRSSLSVAEPS-YD
Mvan_3368|M.vanbaalenii_PYR-1 VLGVGVGSLRAEFEMLSAPWE---DRGVRADDAIRALRSSLSVSAPS-YH
TH_3565|M.thermoresistible__bu ILGVGVGSLKAEFDLLDAAWS---DRDARADEAIRALRASLSQSRPH-HD
MSMEG_2896|M.smegmatis_MC2_155 VLGVGIGSLREEFDLIGAPWE---KRGARADDAIRALRASMGRAEPA-YE
MAB_0366|M.abscessus_ATCC_1997 RICAGVGWMREEIEACGGDFD---RRGRAADEAIAVMRALWSTDGPTSHD
MAV_3045|M.avium_104 MVTFGVGWLAREFELLGVPFG---ERGRIADEYLAAIDELWTSDTPR-FD
MLBr_00348|M.leprae_Br4923 ILGLGVSGPQVVEGWYGQPFP---KPLSRTREYIDIVRQVWAREAPVVSD
: * . . : : : : *
Mb0815c|M.bovis_AF2122/97 GRFYTLDGATCDPP----------PVQRPHPPLWIGGEGDRVQRIAAKHA
Rv0791c|M.tuberculosis_H37Rv GRFYTLDGATCDPP----------PVQRPHPPLWIGGEGDRVQRIAAKHA
MMAR_3440|M.marinum_M GEFYSFRDMVVDPC----------AVQ-KRLPIWVGGRTLRSLRRATSLA
MUL_2716|M.ulcerans_Agy99 GEFYSFRDMVVDPC----------AVQ-KRLPIWVGGRTLRSLRRATSLA
Mflv_4544|M.gilvum_PYR-GCK GDFYTFGGMVVEPH----------AEQ-PRVPIWVGGRSRRSLRRAVGLA
Mvan_3368|M.vanbaalenii_PYR-1 GEFHRYQAMMVEPH----------AVQ-PRVPIWVGGRTARSLRRAVGLA
TH_3565|M.thermoresistible__bu GEHYRYSGFIVEPC----------AVQ-DRVPIWVGGRTRRSLRRAVTLG
MSMEG_2896|M.smegmatis_MC2_155 GPFYAFSEMTVLPH----------AER-IDVPIWVGGRTEASLRRAVSLG
MAB_0366|M.abscessus_ATCC_1997 GEFYSFRNAYSYPK----------PVRPQGVPLYIGGHSKAAARRAGRLG
MAV_3045|M.avium_104 GRYVSFADIAFEPK----------PVQKPHLPVWIGGDADAALRRAARFG
MLBr_00348|M.leprae_Br4923 GQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEIC
* . . *: :*. *
Mb0815c|M.bovis_AF2122/97 QGLNVRWWSPQQVTQRRGFLT--------------------------QAS
Rv0791c|M.tuberculosis_H37Rv QGLNVRWWSPQQVTQRRGFLT--------------------------QAS
MMAR_3440|M.marinum_M EG-----WVPFGIS------------------------------------
MUL_2716|M.ulcerans_Agy99 EG-----WVPFGIS------------------------------------
Mflv_4544|M.gilvum_PYR-GCK DG-----WMPFGLR------------------------------------
Mvan_3368|M.vanbaalenii_PYR-1 DG-----WMPFGLT------------------------------------
TH_3565|M.thermoresistible__bu DG-----WMPFGIS------------------------------------
MSMEG_2896|M.smegmatis_MC2_155 DG-----WMPFGLR------------------------------------
MAB_0366|M.abscessus_ATCC_1997 SG-----FQPLGLVG-----------------------------------
MAV_3045|M.avium_104 SG-----WWPFLTPP-----------------------------------
MLBr_00348|M.leprae_Br4923 DG-----WLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIV
.* : *
Mb0815c|M.bovis_AF2122/97 EAAGRDPDTLRLSVTLLLAPTQSGE---------EEVRIREEFASIPEPG
Rv0791c|M.tuberculosis_H37Rv EAAGRDPDTLRLSVTLLLAPTQSGE---------EEVRIREEFASIPEPG
MMAR_3440|M.marinum_M --------LGEARDWLSRFDIGSG---------------FEVVLSSPEPL
MUL_2716|M.ulcerans_Agy99 --------LGEARDWLSRFDIGSG---------------FEVVLSSPEPL
Mflv_4544|M.gilvum_PYR-GCK --------TMQIADMLATVDIPDG---------------FDIVLPAG-PL
Mvan_3368|M.vanbaalenii_PYR-1 --------PARIAEMLAAVDIPDD---------------FDIVLAVG-PL
TH_3565|M.thermoresistible__bu --------AAQISEWLGSVELPDG---------------FEVVLATS-AL
MSMEG_2896|M.smegmatis_MC2_155 --------TSGIRALLDATPTPDG---------------FEVVLSTGHAV
MAB_0366|M.abscessus_ATCC_1997 ------DDLTAAVGVMRAAAVDAG---------------RDPRGLDLVLG
MAV_3045|M.avium_104 ------EQIAEKLDYIKSQPCYDGRPFEVMHGLGTNRVGEGHVARRDVRD
MLBr_00348|M.leprae_Br4923 VTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTAL
: .
Mb0815c|M.bovis_AF2122/97 LIVGTPDRCVERIR------EYQDRGVGHFLFTIPHVVKSDYLHIIGSDI
Rv0791c|M.tuberculosis_H37Rv LIVGTPDRCVERIR------EYQDRGVGHFLFTIPHVVKSDYLHIIGSDI
MMAR_3440|M.marinum_M NPIGDPERTRHLLA------DLAAHGATTICATFAHSSRQQYLDNLHALA
MUL_2716|M.ulcerans_Agy99 NPIGDPERTRHLLA------DLAAHGATTICATFAHSSRQQYLDNLHALA
Mflv_4544|M.gilvum_PYR-GCK DPR-EPSGCLTRLR------ALRDVGATAVTCSVAADSTDHYCAQLASLR
Mvan_3368|M.vanbaalenii_PYR-1 DPR-ARDECLNRLR------ALRDVGATAVTCSLSASSAEHYCDQLASLR
TH_3565|M.thermoresistible__bu DPLGDPDAARRRLD------RLRELGATAVTATVSATSAAHYCEQLAALR
MSMEG_2896|M.smegmatis_MC2_155 DPIGDPAGTRKRLS------GLADAGATVASCTISASSAAHYRDQVARLS
MAB_0366|M.abscessus_ATCC_1997 HGLHRVDQAALDQA------AHAGAGRMLLSASRRATTLEAVLEEMAGCA
MAV_3045|M.avium_104 RPGMSAGQIVDRLG------WLAEQGVTVTAVPVPAVGGVDEYLDYAQWV
MLBr_00348|M.leprae_Br4923 FRSNQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVSAS
.
Mb0815c|M.bovis_AF2122/97 IPRVKTEVTIP-
Rv0791c|M.tuberculosis_H37Rv IPRVKTEVTIP-
MMAR_3440|M.marinum_M ELDSP-------
MUL_2716|M.ulcerans_Agy99 ELDSP-------
Mflv_4544|M.gilvum_PYR-GCK GIV--DEL----
Mvan_3368|M.vanbaalenii_PYR-1 DLV--DEL----
TH_3565|M.thermoresistible__bu DLAMGDAL----
MSMEG_2896|M.smegmatis_MC2_155 EIAGTVEGRGA-
MAB_0366|M.abscessus_ATCC_1997 TRLELGGPR---
MAV_3045|M.avium_104 IEEIKPQLA---
MLBr_00348|M.leprae_Br4923 SVEQVRDLAGLF