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HIGFVSMNTPDDIAPDVLARELEQRGFESLWVGEHPQIPVSAAGSMPPALLHAQQRIWDPLLSLLAAAQA TSTLRLGTAVALPLEHELFTFAKQVATLDRFSAGRLLLGVGVGVRAELAVSSSIAWADRYRALSDMVAAL RVLWTDDEAEHHGEFYDFEPVWCHPKPQQQAGPPLLAAATGPRAIGDCLPWADGWLPGDAAYRDLPAAVA DFRRRAEDAGRDPATLDLTVMAWGDPSEKRLARYRDLGFTRVVIGGGRRDGDPSTTVPFLDRYAAMVTEL K*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1265 | - | - | 100% (282) | luciferase-like protein |
| M. gilvum PYR-GCK | Mflv_1871 | - | 1e-36 | 35.76% (288) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_4839 | - | 1e-30 | 33.86% (251) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 6e-37 | 34.98% (283) | hypothetical protein Mb3106c |
| M. tuberculosis H37Rv | Rv3079c | - | 6e-37 | 34.98% (283) | hypothetical protein Rv3079c |
| M. leprae Br4923 | MLBr_00131 | - | 3e-14 | 27.70% (213) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1059c | - | 2e-34 | 34.98% (263) | hypothetical protein MAB_1059c |
| M. marinum M | MMAR_1575 | - | 2e-36 | 34.63% (283) | oxidoreductase |
| M. avium 104 | MAV_1077 | - | 3e-33 | 34.80% (273) | hypothetical protein MAV_1077 |
| M. smegmatis MC2 155 | MSMEG_6621 | - | 1e-118 | 73.05% (282) | luciferase family protein |
| M. thermoresistible (build 8) | TH_1620 | - | 1e-102 | 68.38% (253) | bacterial luciferase family protein |
| M. ulcerans Agy99 | MUL_3458 | - | 5e-36 | 34.28% (283) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4864 | - | 6e-35 | 36.50% (263) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3106c|M.bovis_AF2122/97 ---MQFGVLTFVTDEGIGPAELGAALEHR----GFESLFLAEHTHIPVNT
Rv3079c|M.tuberculosis_H37Rv ---MQFGVLTFVTDEGIGPAELGAALEHR----GFESLFLAEHTHIPVNT
MMAR_1575|M.marinum_M ---MRVGVLTFVTDEGIGPAELGAALEER----GFESLFLAEHTHIPVNN
MUL_3458|M.ulcerans_Agy99 ---MRVGVLTFVTDEGIGPAELGAALEER----GFESLFLAEHTHIPVNN
MAV_1077|M.avium_104 --------MLFTSDRGISPAAAAKLADDH----GFATFYVPEHTHIPIKR
Mvan_4864|M.vanbaalenii_PYR-1 ---MNYGLVLFTSDRGITPAAAAKLADEH----GFETFYVPEHTHIPIKR
MAB_1059c|M.abscessus_ATCC_199 ---MDYGLVLFTSDRGISPAIAAKAAEDG----GFSTFYVPEHTHIPVKR
Mflv_1265|M.gilvum_PYR-GCK ---MHIGFVSMNTPDDIAPDVLARELEQR----GFESLWVGEHPQIPVSA
MSMEG_6621|M.smegmatis_MC2_155 ---MDLGFVSLNTPRDLAPDVLARELESR----GFESLWVGEHPQIPVAA
TH_1620|M.thermoresistible__bu -------------------------------------MWVGEHPKIPVAA
MLBr_00131|M.leprae_Br4923 MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNALVPR
:: :* : :
Mb3106c|M.bovis_AF2122/97 QSPYPGGG--PIP-E-KYYRTLDPFVALA--AAAATTQSLVLGTGIALIP
Rv3079c|M.tuberculosis_H37Rv QSPYPGGG--PIP-E-KYYRTLDPFVALA--AAAATTQSLVLGTGIALIP
MMAR_1575|M.marinum_M QSPYPPGG--PIP-R-KYYRTLDPFVALT--AAAVATESLVLGTGIALIP
MUL_3458|M.ulcerans_Agy99 QSPYPPGG--PIP-R-KYYRTLDPFVALT--AAAVATESLVLGTGIALIP
MAV_1077|M.avium_104 EAAHPTTGDASLPDD-RYMRTLDPWVSLG--AACAVTSRVRLSTAVALPV
Mvan_4864|M.vanbaalenii_PYR-1 QAAHPTTGDESLPDD-RYMRTLDPWVSLG--TAAAVTSRVRLSTAVALPV
MAB_1059c|M.abscessus_ATCC_199 EAAHPGTGGAELPDD-RYMRTLDPWVSLG--AACAVTSKIRLATAVAIPV
Mflv_1265|M.gilvum_PYR-GCK AGSMPPALLHAQQ------RIWDPLLSLL--AAAQATSTLRLGTAVALPL
MSMEG_6621|M.smegmatis_MC2_155 AGQFHPGLLRAQR------QIRDPLLSLM--MAAQATTTLRLATAVALPL
TH_1620|M.thermoresistible__bu GDRFPPALLGSQK------QMWDPLLSLL--AAAQATSALRIGTAVALPL
MLBr_00131|M.leprae_Br4923 SVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVTDAG
:* * * : :.. ::
Mb3106c|M.bovis_AF2122/97 ERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRVID
Rv3079c|M.tuberculosis_H37Rv ERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRVID
MMAR_1575|M.marinum_M ERDPIVTAKEVASLDVVSGGRFCFGVGVGWLREEVANHGVDPAVRGRVTD
MUL_3458|M.ulcerans_Agy99 ERDPIVTAKEVASLDVVSGGRFCFGVGVGWLREEVANHGVDPAVRGRVSD
MAV_1077|M.avium_104 EHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHGVPAGRRRTMLR
Mvan_4864|M.vanbaalenii_PYR-1 EHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHNVPPGRRRTMLR
MAB_1059c|M.abscessus_ATCC_199 EHDPITLAKSIATLDHMSGGRVTVGVGYGWNTDELADHHVPAGRRRTMLR
Mflv_1265|M.gilvum_PYR-GCK EHELFTFAKQVATLDRFSAGRLLLGVGVGVRAELAVSSSIAWADRYRALS
MSMEG_6621|M.smegmatis_MC2_155 EHELFTLAKQVATLDRMSGGRLLFGVGVGARAELEVATSIPWQARYRALG
TH_1620|M.thermoresistible__bu ERELFTFAKEAATLDRLSAGRLLLGVGVGVRPEFELLQSVPWSARYRALG
MLBr_00131|M.leprae_Br4923 RRNPAVTAQAAATLHLLTRGKAMLGIGVGER-EGNEPYGVEWTKPVARFQ
.:: . *: *:*. .: *: .*:* * : :
Mb3106c|M.bovis_AF2122/97 ERLRAIIEIWTQ--EQAEFHGTYVDFDPIYCWPKPVTKPYPPLY-VGGGP
Rv3079c|M.tuberculosis_H37Rv ERLRAIIEIWTQ--EQAEFHGTYVDFDPIYCWPKPVTKPYPPLY-VGGGP
MMAR_1575|M.marinum_M ERLGAMIEIWTQ--DNAEYHGKYVDFDPICCWPKPVTKPHPPLY-IGGGP
MUL_3458|M.ulcerans_Agy99 ERLGAMIEIWTQ--DNAEYHGKYVDFDPICCWPKPVTKPHPPLY-IGGGP
MAV_1077|M.avium_104 EYLEAMRALWTQ--EEAAYDGEFVKFGPSWAWPKPVQPHIPVLVGAAGNE
Mvan_4864|M.vanbaalenii_PYR-1 EYLEAMRALWTQ--EEAEFDGEFVKFGPSWAWPKPVQAHIPVLVGAAGTE
MAB_1059c|M.abscessus_ATCC_199 EYIEAMRRLWEE--EEASYSGEFVNFGPSWAWPKTVQKHVPVIVGAGGTE
Mflv_1265|M.gilvum_PYR-GCK DMVAALRVLWTD--DEAEHHGEFYDFEPVWCHPKPQQQAGPPLLAAATGP
MSMEG_6621|M.smegmatis_MC2_155 DMVGALDALWRD--DESEHHGEFFDFDPVWSHPKPHQRPRPPVLAAATGP
TH_1620|M.thermoresistible__bu DMLNALKALWTE--DEAEHHGEFFAFEPVWSSPKPHQRPHPPLLAAATGP
MLBr_00131|M.leprae_Br4923 EALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRGKWPEIWVAAHGP
: : :: :* . : . : : . * : .
Mb3106c|M.bovis_AF2122/97 ANFPRIARLNAGWIAIS-PSPQRLSGPLQRLR---AMAGGD---------
Rv3079c|M.tuberculosis_H37Rv ANFPRIARLNAGWIAIS-PSPQRLSGPLQRLR---AMAGGD---------
MMAR_1575|M.marinum_M ASFGRIARLGAGWIAIS-PSPQLLAGPLEELR---SLAGED---------
MUL_3458|M.ulcerans_Agy99 ASFGRIARLGAGWIAIS-PSPQLLAGPLEELR---SLAGEE---------
MAV_1077|M.avium_104 KNFKWIARSADGWITT--PRDFDIDEPVKLLQDTWAAAGRDG--------
Mvan_4864|M.vanbaalenii_PYR-1 KNFKWIAKSADGWITT--PRDFTIDEPVKLLQDTWAAAGRDG--------
MAB_1059c|M.abscessus_ATCC_199 KNFTWIAKNADGWMST--PRDEDIAGKIVALKEAWKAAGRDG--------
Mflv_1265|M.gilvum_PYR-GCK RAIGDCLPWADGWLPGD-AAYRDLPAAVADFRRRAEDAGRDPA-------
MSMEG_6621|M.smegmatis_MC2_155 NAIRECLAWADGWLPGD-AALRDVERALTRFRRTAEDAGRDPA-------
TH_1620|M.thermoresistible__bu KAVRECASWADGWLPGD-AALPDVGTALTEFRRAVADAGRDPG-------
MLBr_00131|M.leprae_Br4923 RMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDPMSITPAAV
. .*:. : .: ** :
Mb3106c|M.bovis_AF2122/97 --------------------------------------------------
Rv3079c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1575|M.marinum_M --------------------------------------------------
MUL_3458|M.ulcerans_Agy99 --------------------------------------------------
MAV_1077|M.avium_104 --------------------------------------------------
Mvan_4864|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1059c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1265|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6621|M.smegmatis_MC2_155 --------------------------------------------------
TH_1620|M.thermoresistible__bu --------------------------------------------------
MLBr_00131|M.leprae_Br4923 RGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMGADFAGVQ
Mb3106c|M.bovis_AF2122/97 ------------------------VPVTVCQWGEAAAKDLEGYRHLGVER
Rv3079c|M.tuberculosis_H37Rv ------------------------VPVTVCQWGEAAAKDLEGYRHLGVER
MMAR_1575|M.marinum_M ------------------------VAVTVCLSDETKVSDLEGYLPLGVER
MUL_3458|M.ulcerans_Agy99 ------------------------VAVTVCLSDETKVSDLEGYLPLGVER
MAV_1077|M.avium_104 ------------------------APQIVALDFKPDAEKLARWAELGVTE
Mvan_4864|M.vanbaalenii_PYR-1 ------------------------APQIVALDFKPDPEKLAHWREIGVTE
MAB_1059c|M.abscessus_ATCC_199 ------------------------DPLIYVLAGKPDPEQLAAWRELGVTE
Mflv_1265|M.gilvum_PYR-GCK -----------------------TLDLTVMAWGDPSEKRLARYRDLGFTR
MSMEG_6621|M.smegmatis_MC2_155 -----------------------TLDLTIMAWGDPGVDVLARYRDLGFNR
TH_1620|M.thermoresistible__bu -----------------------TLELTIMVWGDPSPGRLARYRELGFHR
MLBr_00131|M.leprae_Br4923 DIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEWRDHGLKY
. : : *.
Mb3106c|M.bovis_AF2122/97 VLLELPTEPR---DPTLRYLDKLQAELARLA--
Rv3079c|M.tuberculosis_H37Rv VLLELPTEPR---DPTLRYLDKLQAELARLA--
MMAR_1575|M.marinum_M VLLGLPTEPR---DQTLRYLDQMESELVQLG--
MUL_3458|M.ulcerans_Agy99 VLLGLPTEPR---DQTLRYLDQMESELVQLG--
MAV_1077|M.avium_104 VLFGLPDKSE---DEVAAYVERLAGKLAALV--
Mvan_4864|M.vanbaalenii_PYR-1 VLFGLPDKSE---ADVAAYVERLAGKLGALT--
MAB_1059c|M.abscessus_ATCC_199 AIFGMPDRSE---EEVRAYIDRLSGKLAAFA--
Mflv_1265|M.gilvum_PYR-GCK VVIGGGRRDG-DPSTTVPFLDRYAAMVTELK--
MSMEG_6621|M.smegmatis_MC2_155 TVIGGGRRGGSDHTATLEFIDHYAEMLGKLS--
TH_1620|M.thermoresistible__bu AIVGGGRRGGSDPSATLAFLDRYATIAHELR--
MLBr_00131|M.leprae_Br4923 LVVINGSLVNSSLRKTVSALLPHARVLRGLKKL
:. . : :