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QGWHPPCGRGLEHVLILGMNYGLVLFTSDRGITPAAAATLADQHGFETFYVPEHTHIPIKRQAAHPTTGD ESLPDDRYMRTLDPWVSLGTAAAVTSRVRLSTAVALPVEHDCITLAKSIATLDHLSGGRVSLGVGFGWNT DELADHNVPPGRRRTMLREYLEAMRALWTQEEAEYDGEFVKFGPSWAWPKPVQSHIPVLVGAAGTEKNFK WIAKSADGWITTPRDFTIDEPVKLLQDTWAAAGRDGAPQIVALDFKPDPDKLAHWRELGVTEVLFGLPDK SESEVAAYVERLAGKLAQLV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1871 | - | - | 100% (301) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_1017 | - | 4e-45 | 38.11% (286) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_1265 | - | 1e-36 | 35.19% (287) | luciferase-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0978c | - | 1e-145 | 87.81% (279) | oxidoreductase |
| M. tuberculosis H37Rv | Rv0953c | - | 1e-145 | 87.81% (279) | oxidoreductase |
| M. leprae Br4923 | MLBr_00269 | - | 8e-11 | 24.63% (268) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1059c | - | 1e-125 | 73.48% (279) | hypothetical protein MAB_1059c |
| M. marinum M | MMAR_4546 | - | 1e-149 | 91.34% (277) | oxidoreductase |
| M. avium 104 | MAV_1077 | - | 1e-149 | 92.06% (277) | hypothetical protein MAV_1077 |
| M. smegmatis MC2 155 | MSMEG_5520 | - | 1e-151 | 90.43% (282) | hypothetical protein MSMEG_5520 |
| M. thermoresistible (build 8) | TH_2830 | - | 1e-147 | 88.13% (278) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_2792 | - | 3e-47 | 40.16% (249) | hypothetical protein MUL_2792 |
| M. vanbaalenii PYR-1 | Mvan_4864 | - | 1e-161 | 96.09% (281) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0978c|M.bovis_AF2122/97 -------------------MHYGLVLFTSDRGITP---AAAARLAESHGF
Rv0953c|M.tuberculosis_H37Rv -------------------MHYGLVLFTSDRGITP---AAAARLAESHGF
Mflv_1871|M.gilvum_PYR-GCK MQGWHPPCGRGLEHVLILGMNYGLVLFTSDRGITP---AAAATLADQHGF
Mvan_4864|M.vanbaalenii_PYR-1 -------------------MNYGLVLFTSDRGITP---AAAAKLADEHGF
MSMEG_5520|M.smegmatis_MC2_155 -------------------MDYGLVLFTSDRGITP---ASAAKLADDHGF
MMAR_4546|M.marinum_M ------------------------MLFTSDRGIAP---AAAARLADDHGF
MAV_1077|M.avium_104 ------------------------MLFTSDRGISP---AAAAKLADDHGF
TH_2830|M.thermoresistible__bu -------------------MDFGLVLFTSDRGITP---AKAATLADDHGF
MAB_1059c|M.abscessus_ATCC_199 -------------------MDYGLVLFTSDRGISP---AIAAKAAEDGGF
MUL_2792|M.ulcerans_Agy99 -------------------MKFGISTFVNDDSIDP---VSLARAIEERGF
MLBr_00269|M.leprae_Br4923 ------------------MAELRLGYKASAEQFAPRELVELGVAAEAHGM
.. : * . . : *:
Mb0978c|M.bovis_AF2122/97 RTFYVPEHTHIPVKRQAAHPTTGDASLPDDRYMRTLDPWVSLGAASAVTS
Rv0953c|M.tuberculosis_H37Rv RTFYVPEHTHIPVKRQAAHPTTGDASLPDDRYMRTLDPWVSLGAASAVTS
Mflv_1871|M.gilvum_PYR-GCK ETFYVPEHTHIPIKRQAAHPTTGDESLPDDRYMRTLDPWVSLGTAAAVTS
Mvan_4864|M.vanbaalenii_PYR-1 ETFYVPEHTHIPIKRQAAHPTTGDESLPDDRYMRTLDPWVSLGTAAAVTS
MSMEG_5520|M.smegmatis_MC2_155 TTFYVPEHTHIPIKREAAHPTTGDESLPDDRYMRTLDPWVSLGTAAAVTS
MMAR_4546|M.marinum_M HTFYVPEHTHIPIKREAAHPTTGDSSLPDDRYMRTLDPWVSLGAASAVTS
MAV_1077|M.avium_104 ATFYVPEHTHIPIKREAAHPTTGDASLPDDRYMRTLDPWVSLGAACAVTS
TH_2830|M.thermoresistible__bu TTFYVPEHTHIPVKREAAHPTTGDSSLPDDRYMRTLDPWVSLATASAVTS
MAB_1059c|M.abscessus_ATCC_199 STFYVPEHTHIPVKREAAHPGTGGAELPDDRYMRTLDPWVSLGAACAVTS
MUL_2792|M.ulcerans_Agy99 SSLVIAEHTHIPASRETPYP--GGDELPG-VYYRTLDPFVTLAAAAAVTS
MLBr_00269|M.leprae_Br4923 DSATVSDH-FQPWRHQGGHAS---------------FSLSWMTAVGERTN
: :.:* . * :: :. . : :. *.
Mb0978c|M.bovis_AF2122/97 RIRLATAVALP-VEHDPITLAKSIATLDHLSHGRVSVGVGFGWNTDELVD
Rv0953c|M.tuberculosis_H37Rv RIRLATAVALP-VEHDPITLAKSIATLDHLSHGRVSVGVGFGWNTDELVD
Mflv_1871|M.gilvum_PYR-GCK RVRLSTAVALP-VEHDCITLAKSIATLDHLSGGRVSLGVGFGWNTDELAD
Mvan_4864|M.vanbaalenii_PYR-1 RVRLSTAVALP-VEHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELAD
MSMEG_5520|M.smegmatis_MC2_155 RVGLSTAVALP-VEHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELAD
MMAR_4546|M.marinum_M RVRLSTAVALP-VEHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELAD
MAV_1077|M.avium_104 RVRLSTAVALP-VEHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELAD
TH_2830|M.thermoresistible__bu RVRLSTAVALP-VEHDPISLAKTIASLDHLSGGRVSLGVGFGWNTDELVD
MAB_1059c|M.abscessus_ATCC_199 KIRLATAVAIP-VEHDPITLAKSIATLDHMSGGRVTVGVGYGWNTDELAD
MUL_2792|M.ulcerans_Agy99 KIELFTGIALL-IQRDPITTAKEAASIDLISGGRFVFGVGAGWNIEELRD
MLBr_00269|M.leprae_Br4923 RILLGTSVLTPTFRYNPAVIGQAFATMGCLYPNRVFLGVGTGEALNEVAT
:: * *.: .. : .: *::. : .*. .*** * :*:
Mb0978c|M.bovis_AF2122/97 HGVPPG----RRRTMLREYLEAMRALWTQEEACYDGEFVKFGPSWAWPKP
Rv0953c|M.tuberculosis_H37Rv HGVPPG----RRRTMLREYLEAMRALWTQEEACYDGEFVKFGPSWAWPKP
Mflv_1871|M.gilvum_PYR-GCK HNVPPG----RRRTMLREYLEAMRALWTQEEAEYDGEFVKFGPSWAWPKP
Mvan_4864|M.vanbaalenii_PYR-1 HNVPPG----RRRTMLREYLEAMRALWTQEEAEFDGEFVKFGPSWAWPKP
MSMEG_5520|M.smegmatis_MC2_155 HKVPAG----RRRTMLREYLEAMRALWTQEEASYDGEFVNFGPSWAWPKP
MMAR_4546|M.marinum_M HGVPPG----RRRTMLREYLEAMRALWTQEEAAYDGEFVKFGPSWAWPKP
MAV_1077|M.avium_104 HGVPAG----RRRTMLREYLEAMRALWTQEEAAYDGEFVKFGPSWAWPKP
TH_2830|M.thermoresistible__bu HGVPPK----RRRTMLREYLEAMRALWTQEEASYQGEFVSFGPSWAWPKP
MAB_1059c|M.abscessus_ATCC_199 HHVPAG----RRRTMLREYIEAMRRLWEEEEASYSGEFVNFGPSWAWPKT
MUL_2792|M.ulcerans_Agy99 HGTDPK----TRGALLDERIEAIKALWTDEPAEYHGKYVDFPPSYSRPKP
MLBr_00269|M.leprae_Br4923 GYQGAWPEFKERFARLRESVRLMRELWRGDRVDFDGDYYQLKGASIYDVP
. * : * * :. :: ** : . : *.: .: : .
Mb0978c|M.bovis_AF2122/97 VQPHIPVLVGAAGTEKNFKWIARSADGWITTPR---DVDIDEPVKLLQDI
Rv0953c|M.tuberculosis_H37Rv VQPHIPVLVGAAGTEKNFKWIARSADGWITTPR---DVDIDEPVKLLQDI
Mflv_1871|M.gilvum_PYR-GCK VQSHIPVLVGAAGTEKNFKWIAKSADGWITTPR---DFTIDEPVKLLQDT
Mvan_4864|M.vanbaalenii_PYR-1 VQAHIPVLVGAAGTEKNFKWIAKSADGWITTPR---DFTIDEPVKLLQDT
MSMEG_5520|M.smegmatis_MC2_155 VQAHIPVLVGAAGNEKNFKWIARSADGWITTPR---DFDIDEPVKLLQDI
MMAR_4546|M.marinum_M VQSHIPVLVGAAGTEKNFKWIARSADGWITTPR---DFDIDAPVKLLQDT
MAV_1077|M.avium_104 VQPHIPVLVGAAGNEKNFKWIARSADGWITTPR---DFDIDEPVKLLQDT
TH_2830|M.thermoresistible__bu VQAHIPVLVGAAGTEKNFKWIARSADGWITTPR---DVDIEEPVKLLQDI
MAB_1059c|M.abscessus_ATCC_199 VQKHVPVIVGAGGTEKNFTWIAKNADGWMSTPR---DEDIAGKIVALKEA
MUL_2792|M.ulcerans_Agy99 VRQPHPPIYIGGNSDATVKRVVRHDAGWISNP-----LPVHQLTQRVDQL
MLBr_00269|M.leprae_Br4923 EGG-VPIYIAAGGPE-VAKYAGRAGEGFVCTSGKGEELYTEKLIPAVLEG
* ... : . : *:: .. : :
Mb0978c|M.bovis_AF2122/97 WAAAGRDGL----PQIVALDVKPVPD----KLARWAELG-VTEVLFGMPD
Rv0953c|M.tuberculosis_H37Rv WAAAGRDGL----PQIVALDVKPVPD----KLARWAELG-VTEVLFGMPD
Mflv_1871|M.gilvum_PYR-GCK WAAAGRDGA----PQIVALDFKPDPD----KLAHWRELG-VTEVLFGLPD
Mvan_4864|M.vanbaalenii_PYR-1 WAAAGRDGA----PQIVALDFKPDPE----KLAHWREIG-VTEVLFGLPD
MSMEG_5520|M.smegmatis_MC2_155 WAAAGREGA----PQIRALDYKPDAE----KLAHWRDLG-VTEVVFGLPD
MMAR_4546|M.marinum_M WAAAGRDGA----PQIVALDFKPVPE----KLARWAELG-VTEVLFGLPD
MAV_1077|M.avium_104 WAAAGRDGA----PQIVALDFKPDAE----KLARWAELG-VTEVLFGLPD
TH_2830|M.thermoresistible__bu WADAGRDGA----PQIVALDFKPDPD----KLARWRDLG-VTEVLFGLPD
MAB_1059c|M.abscessus_ATCC_199 WKAAGRDGD----PLIYVLAGKPDPE----QLAAWRELG-VTEAIFGMPD
MUL_2792|M.ulcerans_Agy99 RSAAGHDVP----LAMFGTRNKPDYW----RAAQDLGFGPAGAAAAHLPA
MLBr_00269|M.leprae_Br4923 AAVAGRDADDIDKMIEIKMSYDPDPEQALSNIRFWAPLSLAAEQKHSIDD
**:: .* . :. . :
Mb0978c|M.bovis_AF2122/97 RSADDAAAYVERLAAKLACCV-----------------------------
Rv0953c|M.tuberculosis_H37Rv RSADDAAAYVERLAAKLACCV-----------------------------
Mflv_1871|M.gilvum_PYR-GCK KSESEVAAYVERLAGKLAQLV-----------------------------
Mvan_4864|M.vanbaalenii_PYR-1 KSEADVAAYVERLAGKLGALT-----------------------------
MSMEG_5520|M.smegmatis_MC2_155 KSEAEVAAYVERLAGKLSALV-----------------------------
MMAR_4546|M.marinum_M RPEDEIAAYVERLAGKLAAMV-----------------------------
MAV_1077|M.avium_104 KSEDEVAAYVERLAGKLAALV-----------------------------
TH_2830|M.thermoresistible__bu RSDDEIAAYVERLAGKLGLS------------------------------
MAB_1059c|M.abscessus_ATCC_199 RSEEEVRAYIDRLSGKLAAFA-----------------------------
MUL_2792|M.ulcerans_Agy99 GGVPAAARRIRCPGGSIPPVEVPGGPSFLREPLARVSCASRRKIAPRFAA
MLBr_00269|M.leprae_Br4923 PIEMEKVADALPIEQVAKRWIVVSDPDEAVARVGQYVTWGLNHLVFHAPG
Mb0978c|M.bovis_AF2122/97 ----------------------
Rv0953c|M.tuberculosis_H37Rv ----------------------
Mflv_1871|M.gilvum_PYR-GCK ----------------------
Mvan_4864|M.vanbaalenii_PYR-1 ----------------------
MSMEG_5520|M.smegmatis_MC2_155 ----------------------
MMAR_4546|M.marinum_M ----------------------
MAV_1077|M.avium_104 ----------------------
TH_2830|M.thermoresistible__bu ----------------------
MAB_1059c|M.abscessus_ATCC_199 ----------------------
MUL_2792|M.ulcerans_Agy99 QCDFASARGGRLRVGSRPR---
MLBr_00269|M.leprae_Br4923 HNQRRFLELFEKDLAPRLRRLG