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DLGFVSLNTPRDLAPDVLARELESRGFESLWVGEHPQIPVAAAGQFHPGLLRAQRQIRDPLLSLMMAAQA TTTLRLATAVALPLEHELFTLAKQVATLDRMSGGRLLFGVGVGARAELEVATSIPWQARYRALGDMVGAL DALWRDDESEHHGEFFDFDPVWSHPKPHQRPRPPVLAAATGPNAIRECLAWADGWLPGDAALRDVERALT RFRRTAEDAGRDPATLDLTIMAWGDPGVDVLARYRDLGFNRTVIGGGRRGGSDHTATLEFIDHYAEMLGK LS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6621 | - | - | 100% (283) | luciferase family protein |
| M. smegmatis MC2 155 | MSMEG_5520 | - | 2e-33 | 33.90% (295) | hypothetical protein MSMEG_5520 |
| M. smegmatis MC2 155 | MSMEG_2811 | - | 3e-32 | 36.25% (251) | hydride transferase 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0978c | - | 3e-35 | 37.37% (281) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1265 | - | 1e-118 | 73.05% (282) | luciferase-like protein |
| M. tuberculosis H37Rv | Rv0953c | - | 3e-35 | 37.37% (281) | oxidoreductase |
| M. leprae Br4923 | MLBr_00131 | - | 4e-11 | 26.29% (213) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1059c | - | 3e-36 | 35.61% (264) | hypothetical protein MAB_1059c |
| M. marinum M | MMAR_1575 | - | 1e-32 | 34.50% (258) | oxidoreductase |
| M. avium 104 | MAV_1077 | - | 2e-32 | 35.77% (260) | hypothetical protein MAV_1077 |
| M. thermoresistible (build 8) | TH_1620 | - | 1e-104 | 69.44% (252) | bacterial luciferase family protein |
| M. ulcerans Agy99 | MUL_3458 | - | 3e-32 | 34.11% (258) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4864 | - | 5e-35 | 34.36% (291) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6621|M.smegmatis_MC2_155 ---MDLGFVSLNTPRDLAPDVLARELESR----GFESLWVGEHPQIPVAA
Mflv_1265|M.gilvum_PYR-GCK ---MHIGFVSMNTPDDIAPDVLARELEQR----GFESLWVGEHPQIPVSA
TH_1620|M.thermoresistible__bu -------------------------------------MWVGEHPKIPVAA
MAV_1077|M.avium_104 --------MLFTSDRGISPAAAAKLADDH----GFATFYVPEHTHIPIKR
Mvan_4864|M.vanbaalenii_PYR-1 ---MNYGLVLFTSDRGITPAAAAKLADEH----GFETFYVPEHTHIPIKR
Mb0978c|M.bovis_AF2122/97 ---MHYGLVLFTSDRGITPAAAARLAESH----GFRTFYVPEHTHIPVKR
Rv0953c|M.tuberculosis_H37Rv ---MHYGLVLFTSDRGITPAAAARLAESH----GFRTFYVPEHTHIPVKR
MAB_1059c|M.abscessus_ATCC_199 ---MDYGLVLFTSDRGISPAIAAKAAEDG----GFSTFYVPEHTHIPVKR
MMAR_1575|M.marinum_M ---MRVGVLTFVTDEGIGPAELGAALEER----GFESLFLAEHTHIPVNN
MUL_3458|M.ulcerans_Agy99 ---MRVGVLTFVTDEGIGPAELGAALEER----GFESLFLAEHTHIPVNN
MLBr_00131|M.leprae_Br4923 MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNALVPR
:: :* : :
MSMEG_6621|M.smegmatis_MC2_155 AGQFHPGLLRAQRQ------IRDPLLSLM--MAAQATTTLRLATAVALPL
Mflv_1265|M.gilvum_PYR-GCK AGSMPPALLHAQQR------IWDPLLSLL--AAAQATSTLRLGTAVALPL
TH_1620|M.thermoresistible__bu GDRFPPALLGSQKQ------MWDPLLSLL--AAAQATSALRIGTAVALPL
MAV_1077|M.avium_104 EAAHPTTGDASLPDD-RYMRTLDPWVSLG--AACAVTSRVRLSTAVALPV
Mvan_4864|M.vanbaalenii_PYR-1 QAAHPTTGDESLPDD-RYMRTLDPWVSLG--TAAAVTSRVRLSTAVALPV
Mb0978c|M.bovis_AF2122/97 QAAHPTTGDASLPDD-RYMRTLDPWVSLG--AASAVTSRIRLATAVALPV
Rv0953c|M.tuberculosis_H37Rv QAAHPTTGDASLPDD-RYMRTLDPWVSLG--AASAVTSRIRLATAVALPV
MAB_1059c|M.abscessus_ATCC_199 EAAHPGTGGAELPDD-RYMRTLDPWVSLG--AACAVTSKIRLATAVAIPV
MMAR_1575|M.marinum_M QSPYPPGG--PIPR--KYYRTLDPFVALT--AAAVATESLVLGTGIALIP
MUL_3458|M.ulcerans_Agy99 QSPYPPGG--PIPR--KYYRTLDPFVALT--AAAVATESLVLGTGIALIP
MLBr_00131|M.leprae_Br4923 SVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVTDAG
:* * * : :.. ::
MSMEG_6621|M.smegmatis_MC2_155 EHELFTLAKQVATLDRMSGGRLLFGVGVGARAELEVATSIPWQARYRALG
Mflv_1265|M.gilvum_PYR-GCK EHELFTFAKQVATLDRFSAGRLLLGVGVGVRAELAVSSSIAWADRYRALS
TH_1620|M.thermoresistible__bu ERELFTFAKEAATLDRLSAGRLLLGVGVGVRPEFELLQSVPWSARYRALG
MAV_1077|M.avium_104 EHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHGVPAGRRRTMLR
Mvan_4864|M.vanbaalenii_PYR-1 EHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHNVPPGRRRTMLR
Mb0978c|M.bovis_AF2122/97 EHDPITLAKSIATLDHLSHGRVSVGVGFGWNTDELVDHGVPPGRRRTMLR
Rv0953c|M.tuberculosis_H37Rv EHDPITLAKSIATLDHLSHGRVSVGVGFGWNTDELVDHGVPPGRRRTMLR
MAB_1059c|M.abscessus_ATCC_199 EHDPITLAKSIATLDHMSGGRVTVGVGYGWNTDELADHHVPAGRRRTMLR
MMAR_1575|M.marinum_M ERDPIVTAKEVASLDVVSGGRFCFGVGVGWLREEVANHGVDPAVRGRVTD
MUL_3458|M.ulcerans_Agy99 ERDPIVTAKEVASLDVVSGGRFCFGVGVGWLREEVANHGVDPAVRGRVSD
MLBr_00131|M.leprae_Br4923 RRNPAVTAQAAATLHLLTRGKAMLGIGVGER-EGNEPYGVEWTKPVARFQ
.:: . *: *:*. .: *: .*:* * : :
MSMEG_6621|M.smegmatis_MC2_155 DMVGALDALWRDDE--SEHHGEFFDFDPVWSHPKPHQRPRPPVLAAATG-
Mflv_1265|M.gilvum_PYR-GCK DMVAALRVLWTDDE--AEHHGEFYDFEPVWCHPKPQQQAGPPLLAAATG-
TH_1620|M.thermoresistible__bu DMLNALKALWTEDE--AEHHGEFFAFEPVWSSPKPHQRPHPPLLAAATG-
MAV_1077|M.avium_104 EYLEAMRALWTQEE--AAYDGEFVKFGPSWAWPKPVQP-HIPVLVGAAGN
Mvan_4864|M.vanbaalenii_PYR-1 EYLEAMRALWTQEE--AEFDGEFVKFGPSWAWPKPVQA-HIPVLVGAAGT
Mb0978c|M.bovis_AF2122/97 EYLEAMRALWTQEE--ACYDGEFVKFGPSWAWPKPVQP-HIPVLVGAAGT
Rv0953c|M.tuberculosis_H37Rv EYLEAMRALWTQEE--ACYDGEFVKFGPSWAWPKPVQP-HIPVLVGAAGT
MAB_1059c|M.abscessus_ATCC_199 EYIEAMRRLWEEEE--ASYSGEFVNFGPSWAWPKTVQK-HVPVIVGAGGT
MMAR_1575|M.marinum_M ERLGAMIEIWTQDN--AEYHGKYVDFDPICCWPKPVTKPHPPLYIGGG--
MUL_3458|M.ulcerans_Agy99 ERLGAMIEIWTQDN--AEYHGKYVDFDPICCWPKPVTKPHPPLYIGGG--
MLBr_00131|M.leprae_Br4923 EALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRGKWPEIWVAAHG-
: : :: :* .: .:: : . : ..
MSMEG_6621|M.smegmatis_MC2_155 PNAIRECLAWADGWLPGDAALR-DVERALTRFRRTAEDAGRDPATLD---
Mflv_1265|M.gilvum_PYR-GCK PRAIGDCLPWADGWLPGDAAYR-DLPAAVADFRRRAEDAGRDPATLD---
TH_1620|M.thermoresistible__bu PKAVRECASWADGWLPGDAALP-DVGTALTEFRRAVADAGRDPGTLE---
MAV_1077|M.avium_104 EKNFKWIARSADGWITTPRDF--DIDEPVKLLQDTWAAAGRDGAPQI---
Mvan_4864|M.vanbaalenii_PYR-1 EKNFKWIAKSADGWITTPRDF--TIDEPVKLLQDTWAAAGRDGAPQI---
Mb0978c|M.bovis_AF2122/97 EKNFKWIARSADGWITTPRDV--DIDEPVKLLQDIWAAAGRDGLPQI---
Rv0953c|M.tuberculosis_H37Rv EKNFKWIARSADGWITTPRDV--DIDEPVKLLQDIWAAAGRDGLPQI---
MAB_1059c|M.abscessus_ATCC_199 EKNFTWIAKNADGWMSTPRDE--DIAGKIVALKEAWKAAGRDGDPLI---
MMAR_1575|M.marinum_M PASFGRIARLGAGWIAISPSP--QLLAGP--LEELRSLAG-EDVAVT---
MUL_3458|M.ulcerans_Agy99 PASFGRIARLGAGWIAISPSP--QLLAGP--LEELRSLAG-EEVAVT---
MLBr_00131|M.leprae_Br4923 PRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDPMSITPAA
. . .*:. .. ** : .
MSMEG_6621|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1265|M.gilvum_PYR-GCK --------------------------------------------------
TH_1620|M.thermoresistible__bu --------------------------------------------------
MAV_1077|M.avium_104 --------------------------------------------------
Mvan_4864|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0978c|M.bovis_AF2122/97 --------------------------------------------------
Rv0953c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1059c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1575|M.marinum_M --------------------------------------------------
MUL_3458|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00131|M.leprae_Br4923 VRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMGADFAGV
MSMEG_6621|M.smegmatis_MC2_155 ---------------------------LTIMAWGDPGVDVLARYRDLGFN
Mflv_1265|M.gilvum_PYR-GCK ---------------------------LTVMAWGDPSEKRLARYRDLGFT
TH_1620|M.thermoresistible__bu ---------------------------LTIMVWGDPSPGRLARYRELGFH
MAV_1077|M.avium_104 ---------------------------VALDFK--PDAEKLARWAELGVT
Mvan_4864|M.vanbaalenii_PYR-1 ---------------------------VALDFK--PDPEKLAHWREIGVT
Mb0978c|M.bovis_AF2122/97 ---------------------------VALDVK--PVPDKLARWAELGVT
Rv0953c|M.tuberculosis_H37Rv ---------------------------VALDVK--PVPDKLARWAELGVT
MAB_1059c|M.abscessus_ATCC_199 ---------------------------YVLAGK--PDPEQLAAWRELGVT
MMAR_1575|M.marinum_M ---------------------------VCLSDE--TKVSDLEGYLPLGVE
MUL_3458|M.ulcerans_Agy99 ---------------------------VCLSDE--TKVSDLEGYLPLGVE
MLBr_00131|M.leprae_Br4923 QDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEWRDHGLK
. : : *.
MSMEG_6621|M.smegmatis_MC2_155 RTVIGGGRRGGSDHTATLEFIDHYAEMLGKLS--
Mflv_1265|M.gilvum_PYR-GCK RVVIGGGRRDG-DPSTTVPFLDRYAAMVTELK--
TH_1620|M.thermoresistible__bu RAIVGGGRRGGSDPSATLAFLDRYATIAHELR--
MAV_1077|M.avium_104 EVLFG---LPDKSEDEVAAYVERLAGKLAALV--
Mvan_4864|M.vanbaalenii_PYR-1 EVLFG---LPDKSEADVAAYVERLAGKLGALT--
Mb0978c|M.bovis_AF2122/97 EVLFG---MPDRSADDAAAYVERLAAKLACCV--
Rv0953c|M.tuberculosis_H37Rv EVLFG---MPDRSADDAAAYVERLAAKLACCV--
MAB_1059c|M.abscessus_ATCC_199 EAIFG---MPDRSEEEVRAYIDRLSGKLAAFA--
MMAR_1575|M.marinum_M RVLLG---LPTEPRDQTLRYLDQMESELVQLG--
MUL_3458|M.ulcerans_Agy99 RVLLG---LPTEPRDQTLRYLDQMESELVQLG--
MLBr_00131|M.leprae_Br4923 YLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL
:. . :