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MRIALLSYRSKTHCGGQGVYVRHLSRGLVELGHDVEVFSGQPYPEILDPRVRLTEVPSLDLYREPDPFRI PRPSEIRSSIDLEELLTTWTAGFPEPKTFSMRAARLLAARRGDFDVVHDNQCLGTGLLTIAESGMPVVAT VHHPITRDKVLEVAAAKWWRKPLVRRWYGFAEMQKDVARKIPELVTVSSTSAADIAEDFGVTPEQLNVVP LGVDTQLFQPAEHRVRNRIIAIASADVPLKGVSHLLHAVARLRVERDLELQLVAKLEPNGPTEKLIAELG ISDIVHISSGLSDSELAGLLASAEVACIPSLYEGFSLPAVEAMASGTPIVASRAGALPEVVGADGQCARL VKPADVAELTSVLGELLDSPRELRRLGDNGRRRALEVFSWESVAAQTVAVYERACERVATC
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1099 | - | - | 100% (411) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_4262 | - | 1e-22 | 26.60% (406) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_3449 | - | 1e-19 | 27.40% (427) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3058 | - | 2e-23 | 27.67% (412) | transferase |
| M. tuberculosis H37Rv | Rv3032 | - | 2e-23 | 27.67% (412) | transferase |
| M. leprae Br4923 | MLBr_01715 | - | 2e-23 | 26.60% (421) | putative transferase |
| M. abscessus ATCC 19977 | MAB_3366 | - | 3e-21 | 26.23% (427) | glycosyltransferase |
| M. marinum M | MMAR_2925 | - | 0.0 | 78.83% (411) | glycosyltransferase |
| M. avium 104 | MAV_2755 | - | 1e-176 | 80.00% (390) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_6484 | - | 0.0 | 85.29% (408) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_0088 | - | 0.0 | 84.90% (404) | glycosyl transferase |
| M. ulcerans Agy99 | MUL_3252 | pimA | 3e-21 | 31.46% (302) | alpha-mannosyltransferase PimA |
| M. vanbaalenii PYR-1 | Mvan_5718 | - | 0.0 | 95.38% (411) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1099|M.gilvum_PYR-GCK ------------------------MRIALLSYRS-KTHCGGQGVYVRHLS
Mvan_5718|M.vanbaalenii_PYR-1 ------------------------MRIALLSYRS-KTHCGGQGVYVRHLS
MSMEG_6484|M.smegmatis_MC2_155 ------------------------MRIALLSYRS-KTHCGGQGVYVRHLS
TH_0088|M.thermoresistible__bu ------------------------MRIALLSYRS-KTHCGGQGVYVRHLS
MMAR_2925|M.marinum_M ------------------------MRIALLSYRS-KTHCGGQGVYVRHLS
MAV_2755|M.avium_104 ---------------------------------------------MRHLS
Mb3058|M.bovis_AF2122/97 ------------------------MRILMVSWEYPPVVIGGLGRHVHHLS
Rv3032|M.tuberculosis_H37Rv ------------------------MRILMVSWEYPPVVIGGLGRHVHHLS
MLBr_01715|M.leprae_Br4923 MFIQRHAVVRGIFGTFAPAEGTTLMKILIVSWEYPPVVIGGLGRHVHHLS
MAB_3366|M.abscessus_ATCC_1997 ------------------------MRILMVSWEYPPVVIGGLGRHVHHLS
MUL_3252|M.ulcerans_Agy99 ------------------------MAHVSATMVGRLVRCPPRAAAGALMR
:
Mflv_1099|M.gilvum_PYR-GCK RGLVELGHDVEVFSGQPYPEILDPRVRLTEVPSLDLYREPDPFRIPRPSE
Mvan_5718|M.vanbaalenii_PYR-1 RGLVELGHDVEVFSGQPYPEILDPRVRLTEVPSLDLYREPDPFRIPRPSE
MSMEG_6484|M.smegmatis_MC2_155 SGLAELGHDVEVFSGQPYPEGLDPRVTLTKVPSLDLYREPDPFRVPHPRE
TH_0088|M.thermoresistible__bu RGLVELGHQVEVFSGQPYPEGLDPRVKLTKVPSLDLYREPDPFRIPRPSE
MMAR_2925|M.marinum_M RGLVDLGHDVEVFSGQPYPELLDPRVRLTEVPSLDLYREPDPFRVPHPSE
MAV_2755|M.avium_104 HGLVELGHDVEVFSGQPYPDLLDPRVRLTEVPSLDLYREPDPFRVPRPSE
Mb3058|M.bovis_AF2122/97 TALAAAGHDVVVLSRC--PSGTDP----STHPSSDEVTEG--VRVIAAAQ
Rv3032|M.tuberculosis_H37Rv TALAAAGHDVVVLSRC--PSGTDP----STHPSSDEVTEG--VRVIAAAQ
MLBr_01715|M.leprae_Br4923 TALAAAGHDVVVLSRR--PSGTDP----CTHPTSDEISEG--VRVIAAAQ
MAB_3366|M.abscessus_ATCC_1997 TELAAAGHDVVVLTRR--PSGTDP----SSHPTSDEISEG--VRVVAAAE
MUL_3252|M.ulcerans_Agy99 IGMVCP-YSFDVAGGVQSHVLQLAEVMRARGHEVSVLAPASPHAALPDYV
:. :.. * . .
Mflv_1099|M.gilvum_PYR-GCK IRSSIDLEELLTTWTAGFPEPKTFSMRAARLLAARRGDFDVVHDNQCLGT
Mvan_5718|M.vanbaalenii_PYR-1 IKTSIDLEELLTTWTAGFPEPKTFSMRAARLLADRRDDFDVVHDNQCLGT
MSMEG_6484|M.smegmatis_MC2_155 IRDGIDALELLTMWSAGFPEPRTFTMRAARILAARRDEFDVVHDNQSLGT
TH_0088|M.thermoresistible__bu IRDRIDLLELLTTWTAGFPEPKTFTMRMARILAERRDEFDVVHDNQSLGT
MMAR_2925|M.marinum_M IRDSIDLLELFTMWTAGFPEPRTFSLRVARLLADRVGDFDLVHDNQSLGT
MAV_2755|M.avium_104 IRDSIDLLELLTTWTAGFPEPRTFTLRAARLLAGRTADFDVVHDNQSLGT
Mb3058|M.bovis_AF2122/97 DPHEFTFGNDMMAWTLAMG---HAMIRAGLRLKKLGTDRSWRPDVVHAHD
Rv3032|M.tuberculosis_H37Rv DPHEFTFGNDMMAWTLAMG---HAMIRAGLRLKKLGTDRSWRPDVVHAHD
MLBr_01715|M.leprae_Br4923 DPHEFTFSNDMMAWTLAMG---HAMIRTGLSLTRHSSDLPWRPDVVHAHD
MAB_3366|M.abscessus_ATCC_1997 DPHDFDFGTDMMAWTLAMG---HAMVRAGLALGLKGSG-DWRPDVVHAHD
MUL_3252|M.ulcerans_Agy99 VSGGKAVPIPYNGSVARLRFGPATHRKVKKWLSEGDFDVLHLHEPNAPSL
: : * :
Mflv_1099|M.gilvum_PYR-GCK GLLTIAESGMPVVATVHHPITRDKVLEVAAAKWWRKPLVRRWYGFAEMQK
Mvan_5718|M.vanbaalenii_PYR-1 GLLTIADSGMPVVATVHHPITRDRVLEVAAAKWWRKPLVRRWYGFAEMQK
MSMEG_6484|M.smegmatis_MC2_155 GLLKIEKLGLPVVATVHHPITRDKVVDVAAAKWWRKPLVRRWYGFAEMQK
TH_0088|M.thermoresistible__bu GLLELADLGLPVVATVHHPITRDKVVEVAAAKWWRKPLVRRWYGFAEMQK
MMAR_2925|M.marinum_M GLLRIAAMGLPVVATVHHPITRDRVLDLAAARWWRKPLVHRWYGFSAMQK
MAV_2755|M.avium_104 GLLSIAGSGLPVVATVHHPITRDRVLDLAAARWWRKPLVRRWYGFLAMQQ
Mb3058|M.bovis_AF2122/97 WLVAHPAIALAQFYDVPMVSTIHATEAGRHSGWVSGALSRQVH---AVES
Rv3032|M.tuberculosis_H37Rv WLVAHPAIALAQFYDVPMVSTIHATEAGRHSGWVSGALSRQVH---AVES
MLBr_01715|M.leprae_Br4923 WLVAHPAITLAQFYDVPMVSTIHATEAGRHSGWVSGALSRQVH---AVES
MAB_3366|M.abscessus_ATCC_1997 WLVAHPAIALAEHFDVPLVSTLHATEAGRHSGWVSGRISRQVH---SVEW
MUL_3252|M.ulcerans_Agy99 SMLALNIAEGPIVATFHTSTTKSLTLTVFQS----------------ILR
:: . . * . : :
Mflv_1099|M.gilvum_PYR-GCK DVARKIPELVTVSSTSAADIAEDFGVTPEQLNVVPLGVDTQLFQP----A
Mvan_5718|M.vanbaalenii_PYR-1 QVARQIPELVTVSSTSAADIAEDFAVDPNQLNVVPLGVDTQLFQP----S
MSMEG_6484|M.smegmatis_MC2_155 KVARQIPELLTVSSSSAADIAADFGVTSDQLHIVPLGVNTELFKP----A
TH_0088|M.thermoresistible__bu RVARRIPELITVSSSSAADISADFGVSPGQLHVVPLGVDTELFTP----S
MMAR_2925|M.marinum_M QVARQLPHLLTVSSSSAADIVTDFGVSPDQLNVVPLGVNTELFEPG---V
MAV_2755|M.avium_104 EVARHIPDLLTVSSSSAADIISDFGVSPEQLHVVPLGVNTELFKPG---S
Mb3058|M.bovis_AF2122/97 WLVRESDSLITCSASMNDEITELFGPGLAEITVIRNGIDAARWPFA---A
Rv3032|M.tuberculosis_H37Rv WLVRESDSLITCSASMNDEITELFGPGLAEITVIRNGIDAARWPFA---A
MLBr_01715|M.leprae_Br4923 WLVRESDSLITCSASMCNEIIELFGPGLAEITVIRNGIDPARWPFA---A
MAB_3366|M.abscessus_ATCC_1997 WLARESDSLITCSASMLDEVTQLFGPELPQVHVIRNGIDVTRWVFA---P
MUL_3252|M.ulcerans_Agy99 PMHEKIVGRIAVSDLARRWQMEALGS---DAVEIPNGVDVGSFASSSCLD
: .. :: * :. : : *:: :
Mflv_1099|M.gilvum_PYR-GCK EHRVRN--RIIAIASADVPLKGVSHLLHAVARLR-VERDLELQLVAKLEP
Mvan_5718|M.vanbaalenii_PYR-1 EHRVRN--RIIAIASADVPLKGVSHLLHAVARLR-VERDLELQLVAKLEA
MSMEG_6484|M.smegmatis_MC2_155 EQRVSG--RIIAIASADVPLKGVSHLLHAVARLR-VERNLDLQLVSKLEP
TH_0088|M.thermoresistible__bu EHRVPG--RIIAIASADVPLKGISHLLHAVARLR-AKRNLDVQLVSKLEP
MMAR_2925|M.marinum_M SPRKPG--RVMAIASADTPLKGVSTLLHAVAKLR-VNREIELRLVAKVEP
MAV_2755|M.avium_104 GPRQPG--RIIAIASADTPLKGVRTLLHAVARLR-TVRDLELRLVAKVEP
Mb3058|M.bovis_AF2122/97 RRPRTG-PAELLYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGEGTQ
Rv3032|M.tuberculosis_H37Rv RRPRTG-PAELLYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGEGTQ
MLBr_01715|M.leprae_Br4923 RRARTG-PAELLYVGRLEYEKGVHDVIAALPRIRRSYPGTTLTIAGEGTQ
MAB_3366|M.abscessus_ATCC_1997 RPPADGTPPVLLFVGRLEYEKGIHDAIAALPKIRRAHPGTVLAVAGDGTQ
MUL_3252|M.ulcerans_Agy99 GYPRPG-KTVLFLGRYDEPRKGMSVLLEALPKLVERFIDVQLLIVGRGDE
. : **: : *:.:: : :..
Mflv_1099|M.gilvum_PYR-GCK NGPTEKLIAELGISDIVHISSGLSDSELAGLLASAEVACIP-SLYEGFSL
Mvan_5718|M.vanbaalenii_PYR-1 NGPTEKLIAELGISDIVHISSGLSDSELAALLASAEVACIP-SLYEGFSL
MSMEG_6484|M.smegmatis_MC2_155 NGPTEKLIAELGISDIVHISSGLSDQELAGLLASAEVACIP-SLYEGFSL
TH_0088|M.thermoresistible__bu NGPTEKLIAELGISDIVQASSGLSDSELARLLASAEVACIP-SLYEGFSL
MMAR_2925|M.marinum_M NGPTEKLIAELGISDIVHISNGLSDAQLAALFASAEVACIP-SLYEGFSL
MAV_2755|M.avium_104 NGPTHKLIAELGISDIVHITSGLSDAELAALFASAEVACIP-SLYEGFSL
Mb3058|M.bovis_AF2122/97 QDWLIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLP-SHYEPFGL
Rv3032|M.tuberculosis_H37Rv QDWLIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLP-SHYEPFGL
MLBr_01715|M.leprae_Br4923 QDWLVDQARKYKVIKATRFVGHLNHNELLAALQRADAAVLP-SHYEPFGL
MAB_3366|M.abscessus_ATCC_1997 QDWLLEQARKYKVVKSVQFLGTLDHSELLHWLHHADAILLP-SHYEPFGI
MUL_3252|M.ulcerans_Agy99 DELRDEAG---ELAEHMRFLGQVDDAGKASAMRSADVYCAPNTGGESFGI
: . : : . :.. : *:. * : * *.:
Mflv_1099|M.gilvum_PYR-GCK PAVEAMASGTPIVASRAGALPEVVGADGQCARLVKPADVAELTSVLGELL
Mvan_5718|M.vanbaalenii_PYR-1 PAVEAMASGTPIVASRAGALPEVVGTDGECARLVTPADVTELTAVLGELL
MSMEG_6484|M.smegmatis_MC2_155 PAVEAMASGTPIVASRAGALPEVVGTDGSCARLVRPADVDELTAVLGELL
TH_0088|M.thermoresistible__bu PAVEAMASGTPIVASRAGALPEVLGPDGECARLVPPADVDALTRVLGELL
MMAR_2925|M.marinum_M PAVEAMASGTPIVASRVGALPEVLGTDGACAQLVPAADVGALTYALGELL
MAV_2755|M.avium_104 PAVEAMASGTPIVASRVGALPEVLGTDGACAELVPPADVDALTRALGELL
Mb3058|M.bovis_AF2122/97 VALEAAAAGTPLVTSNIGGLGEAV-INGQTGVSCAPRDVAGLAAAVRSVL
Rv3032|M.tuberculosis_H37Rv VALEAAAAGTPLVTSNIGGLGEAV-INGQTGVSCAPRDVAGLAAAVRSVL
MLBr_01715|M.leprae_Br4923 VALEAAAAGTPLVTSNIGGLGEAV-INGQTGVSCPPRDIAELAAMVCTVL
MAB_3366|M.abscessus_ATCC_1997 VALEAAAAGTPLVTSTVGGLGEAV-IDGETGMSFAPRDVAGIAEAVTRTL
MUL_3252|M.ulcerans_Agy99 VLVEAMAAGTPVVASDLDAFRRVL-RDGEIGRLVPVDDSDALAAALIEVL
:** *:***:*:* ..: ..: :* . * :: : *
Mflv_1099|M.gilvum_PYR-GCK DSPRELRRLGDNGRRRALEVFSWESVAAQTVAVYERACERVATC------
Mvan_5718|M.vanbaalenii_PYR-1 DSPRELRRLGDNGRRRALEVFSWESVAAQTVAVYERACERVATC------
MSMEG_6484|M.smegmatis_MC2_155 DSPAERRRLGAAGRQRALDVFSWESVAAQTVAVYERAQNRMGVKAC----
TH_0088|M.thermoresistible__bu DSPHQRSRLGAAGRQRALDVFSWESVAAQTVSIYERAIC-----------
MMAR_2925|M.marinum_M DSPDKRRSLGEAGRQRALGVFSWEAVAAQTVRVYAAAIERTTTAPESNAQ
MAV_2755|M.avium_104 DSPEKRRSLGRAGRTRAVDVFSWEAVAAQTVRVYERAIARNAAG---RAP
Mb3058|M.bovis_AF2122/97 DDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPI
Rv3032|M.tuberculosis_H37Rv DDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPI
MLBr_01715|M.leprae_Br4923 EDPDAAQQRALAARERLTSDFDWQTVAQQTAQVYLAAKRRERQPQPRLPI
MAB_3366|M.abscessus_ATCC_1997 DDPAAAAERAVAARARLTADFDWATVADETAQVYLAAKRREREPLGRSVI
MUL_3252|M.ulcerans_Agy99 DSQELRERYVAAG-TEAVRRYDWSVVASQIMRVYETVAGAGVKVQVAS--
:. . . :.* ** :* .
Mflv_1099|M.gilvum_PYR-GCK --------
Mvan_5718|M.vanbaalenii_PYR-1 --------
MSMEG_6484|M.smegmatis_MC2_155 --------
TH_0088|M.thermoresistible__bu --------
MMAR_2925|M.marinum_M C-------
MAV_2755|M.avium_104 C-------
Mb3058|M.bovis_AF2122/97 VEHALPDR
Rv3032|M.tuberculosis_H37Rv VEHALPDR
MLBr_01715|M.leprae_Br4923 VEHALPDR
MAB_3366|M.abscessus_ATCC_1997 VERPLPDR
MUL_3252|M.ulcerans_Agy99 --------