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RLAVVGDLSGVGATDRGGGGRYGIADLAQALARRGHEVRVHTALPHPAGVQPTGVAVDHVPVATVAVETS PELMPAIGEISRHLVDVWRRDTPDVVHCHGWVYGMAAQLAAKKTPVPIVQTFHELSTPGRRESAGGQAAT AAKLEALLARNATALTAGCHDDVQTLIRLGCPRAKVSVLSAGVEVDDAVEIESRGGDVPPRIVAVARDFG AEQGLADVVAALPSLGAADLTLVATDPTGPDAGHLGDVARRLRVADRVRMMRGDECPELAALLPSADVVV LPARYEPSSEFVLQAMACGAPVVAFAAGGARDAVIEDVTGLLVQPGDVNALGRAVRTALSQPVLRQGMGL AGRSRARSRYSWDRIATDAEVAYLAAAARHSGQAPAGDRGPGTRGSLRPQSCSPVTRK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3449 | - | - | 100% (409) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_4262 | - | 4e-36 | 31.59% (383) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_2191 | - | 4e-22 | 31.41% (347) | glycogen synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3058 | - | 1e-30 | 31.11% (389) | transferase |
| M. tuberculosis H37Rv | Rv3032 | - | 1e-30 | 31.11% (389) | transferase |
| M. leprae Br4923 | MLBr_01715 | - | 1e-30 | 30.81% (396) | putative transferase |
| M. abscessus ATCC 19977 | MAB_3366 | - | 2e-29 | 29.41% (391) | glycosyltransferase |
| M. marinum M | MMAR_1681 | - | 2e-27 | 29.56% (389) | transferase |
| M. avium 104 | MAV_4082 | - | 3e-61 | 39.21% (403) | transferase |
| M. smegmatis MC2 155 | MSMEG_6484 | - | 8e-25 | 28.54% (424) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_3188 | - | 6e-62 | 39.43% (383) | PUTATIVE glycosyl transferase, group 1 |
| M. ulcerans Agy99 | MUL_1919 | - | 3e-28 | 29.82% (389) | transferase |
| M. vanbaalenii PYR-1 | Mvan_3205 | - | 1e-112 | 56.44% (388) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1681|M.marinum_M ------------------------MKILMVSWEYPPVVIGGLGRHVHHLA
MUL_1919|M.ulcerans_Agy99 ------------------------MKILMVSWEYPPVVIGGLGRHVHHLA
Mb3058|M.bovis_AF2122/97 ------------------------MRILMVSWEYPPVVIGGLGRHVHHLS
Rv3032|M.tuberculosis_H37Rv ------------------------MRILMVSWEYPPVVIGGLGRHVHHLS
MLBr_01715|M.leprae_Br4923 MFIQRHAVVRGIFGTFAPAEGTTLMKILIVSWEYPPVVIGGLGRHVHHLS
MAB_3366|M.abscessus_ATCC_1997 ------------------------MRILMVSWEYPPVVIGGLGRHVHHLS
Mflv_3449|M.gilvum_PYR-GCK ---------------------MRLAVVGDLSGVGATDRGGGGRYGIADLA
Mvan_3205|M.vanbaalenii_PYR-1 ---------------------MKLALVGELP--------GGHGYDLTRLG
MAV_4082|M.avium_104 -----------------MRIAMISEHASPLAHLGG-VDAGGQNVHVAELS
TH_3188|M.thermoresistible__bu ---------------------MVSEHASPLAALGG-VDAGGQNVHVAELS
MSMEG_6484|M.smegmatis_MC2_155 ------------------------MRIALLSYRSK-THCGGQGVYVRHLS
:. ** : *.
MMAR_1681|M.marinum_M TALVAAGHEVVVLSRRPSGTDPSTHPSSDLIS--------EGVRVIAAAQ
MUL_1919|M.ulcerans_Agy99 TALVAAGHEVVVLSRRPSGTDPSTHPSSDLIS--------EGVRVIAAAQ
Mb3058|M.bovis_AF2122/97 TALAAAGHDVVVLSRCPSGTDPSTHPSSDEVT--------EGVRVIAAAQ
Rv3032|M.tuberculosis_H37Rv TALAAAGHDVVVLSRCPSGTDPSTHPSSDEVT--------EGVRVIAAAQ
MLBr_01715|M.leprae_Br4923 TALAAAGHDVVVLSRRPSGTDPCTHPTSDEIS--------EGVRVIAAAQ
MAB_3366|M.abscessus_ATCC_1997 TELAAAGHDVVVLTRRPSGTDPSSHPTSDEIS--------EGVRVVAAAE
Mflv_3449|M.gilvum_PYR-GCK QALARRGHEVRVHT--------ALPHPAGVQP--------TGVAVDHVPV
Mvan_3205|M.vanbaalenii_PYR-1 DALVGRGHKVQVFT--------ATVPAMRYTP--------AGAAVQRLPV
MAV_4082|M.avium_104 CALARRGHDVVVYTRR----DDPRLPDSVETP--------HGYSVVHVPA
TH_3188|M.thermoresistible__bu AALTRRGHEVTVYTRR----DDRGLPDRVDTP--------LGYTVVHVPA
MSMEG_6484|M.smegmatis_MC2_155 SGLAELGHDVEVFSGQPYPEGLDPRVTLTKVPSLDLYREPDPFRVPHPRE
*. **.* * : . *
MMAR_1681|M.marinum_M DPHEFSFGSDMMAWTLAMGHAMVRAGLTLSGPGAEQPWQPDIVHAHDWLV
MUL_1919|M.ulcerans_Agy99 DPHEFSFGSDMMAWTLAMGHAMVRAGLTLSGPGAEQPWQPDIVHAHDWLV
Mb3058|M.bovis_AF2122/97 DPHEFTFGNDMMAWTLAMGHAMIRAGLRLKKLGTDRSWRPDVVHAHDWLV
Rv3032|M.tuberculosis_H37Rv DPHEFTFGNDMMAWTLAMGHAMIRAGLRLKKLGTDRSWRPDVVHAHDWLV
MLBr_01715|M.leprae_Br4923 DPHEFTFSNDMMAWTLAMGHAMIRTGLSLTRHSSDLPWRPDVVHAHDWLV
MAB_3366|M.abscessus_ATCC_1997 DPHDFDFGTDMMAWTLAMGHAMVRAGLALGLKGSGD-WRPDVVHAHDWLV
Mflv_3449|M.gilvum_PYR-GCK ATVAVETSPELMPAIGEISRHLVDVWRRDT---------PDVVHCHGWVY
Mvan_3205|M.vanbaalenii_PYR-1 DTTGVESSEDLMPLIGEMGRHLVDVWEADG---------PDVVHCHGWVY
MAV_4082|M.avium_104 GPARVLPKDELLQYMYGFAQFLRQQWCSDG---------PDVAHAHFWMS
TH_3188|M.thermoresistible__bu GPAEQLPKDELLPYMGPFAQFLDAEWSAHR---------PDVVHAHFWMS
MSMEG_6484|M.smegmatis_MC2_155 IRDGIDALELLTMWSAGFPEPRTFTMRAARILAARR---DEFDVVHDNQS
: : . :. *
MMAR_1681|M.marinum_M AHPAIALADYYDVPMVSTIHATEAG-RHSGWVSGDLSRQ--------VHA
MUL_1919|M.ulcerans_Agy99 AHPAIALADYYDVPMVSTIHATEAG-RHSGWVSGDLSRQ--------VHA
Mb3058|M.bovis_AF2122/97 AHPAIALAQFYDVPMVSTIHATEAG-RHSGWVSGALSRQ--------VHA
Rv3032|M.tuberculosis_H37Rv AHPAIALAQFYDVPMVSTIHATEAG-RHSGWVSGALSRQ--------VHA
MLBr_01715|M.leprae_Br4923 AHPAITLAQFYDVPMVSTIHATEAG-RHSGWVSGALSRQ--------VHA
MAB_3366|M.abscessus_ATCC_1997 AHPAIALAEHFDVPLVSTLHATEAG-RHSGWVSGRISRQ--------VHS
Mflv_3449|M.gilvum_PYR-GCK GMAAQLAAKKTPVPIVQTFHELSTPGRRESA--GGQAAT--------AAK
Mvan_3205|M.vanbaalenii_PYR-1 GMAAQLAARRCRIPTVQSFPELSVSAGGDRG--EGLADK--------RIQ
MAV_4082|M.avium_104 GVATQQAARAHSIPTVQTFHALGLTKRLHQGSDDTSPDC--------RID
TH_3188|M.thermoresistible__bu GIATQLASRHLDLPAVQTFHALGVVKKRHQGAEDTSPQE--------RLQ
MSMEG_6484|M.smegmatis_MC2_155 LGTGLLKIEKLGLPVVATVHHPITRDKVVDVAAAKWWRKPLVRRWYGFAE
. :* * :.
MMAR_1681|M.marinum_M VESWLVRESDSLITCSGSMSDEITELFGPGLAETAVIRNGIDAAR-WPFA
MUL_1919|M.ulcerans_Agy99 VESWLVRESDSLITCSGSMSDEITELFGPGLAETAVIRNGIDVAR-WPFA
Mb3058|M.bovis_AF2122/97 VESWLVRESDSLITCSASMNDEITELFGPGLAEITVIRNGIDAAR-WPFA
Rv3032|M.tuberculosis_H37Rv VESWLVRESDSLITCSASMNDEITELFGPGLAEITVIRNGIDAAR-WPFA
MLBr_01715|M.leprae_Br4923 VESWLVRESDSLITCSASMCNEIIELFGPGLAEITVIRNGIDPAR-WPFA
MAB_3366|M.abscessus_ATCC_1997 VEWWLARESDSLITCSASMLDEVTQLFGPELPQVHVIRNGIDVTR-WVFA
Mflv_3449|M.gilvum_PYR-GCK LEALLARNATALTAGCHDDVQTLIR-LGCPRAKVSVLSAGVEVDD--AVE
Mvan_3205|M.vanbaalenii_PYR-1 LEALLARNATAVTVACNDDMREIIR-LGCTRAKASVLAPGIDVDDVCAEE
MAV_4082|M.avium_104 VEARVAREADWVAATSTDEVFELVR-MGRARSRTSVVPCGVDLDAFTPDG
TH_3188|M.thermoresistible__bu LEAMVARGANWVAATCTDEVFELMR-MGRSRSRISVVPCGVDLDLFTPDG
MSMEG_6484|M.smegmatis_MC2_155 MQKKVARQIPELLTVSSSSAADIAADFGVTSDQLHIVPLGVNTELFKPAE
:: :.* : . . . : :* . :: *::
MMAR_1681|M.marinum_M VRKPRTG-PPELLYVGR-LEYEKGVHNAIAALPRIRRAHPGTTLTIAG--
MUL_1919|M.ulcerans_Agy99 VRKPRTG-PPELLYVGR-LEYEKGVHNAIAALPRIRRAHPGTTLTIAG--
Mb3058|M.bovis_AF2122/97 ARRPRTG-PAELLYVGR-LEYEKGVHDAIAALPRLRRTHPGTTLTIAG--
Rv3032|M.tuberculosis_H37Rv ARRPRTG-PAELLYVGR-LEYEKGVHDAIAALPRLRRTHPGTTLTIAG--
MLBr_01715|M.leprae_Br4923 ARRARTG-PAELLYVGR-LEYEKGVHDVIAALPRIRRSYPGTTLTIAG--
MAB_3366|M.abscessus_ATCC_1997 PRPPADGTPPVLLFVGR-LEYEKGIHDAIAALPKIRRAHPGTVLAVAG--
Mflv_3449|M.gilvum_PYR-GCK IESRGGDVPPRIVAVARDFGAEQGLADVVAALPSLGAADLTLVATDP---
Mvan_3205|M.vanbaalenii_PYR-1 IVFRHGESSGRVVAVARDFSPQQGLGQVLRVFPSSNAAELVLVTREPD--
MAV_4082|M.avium_104 PVAARGARP-RIVTVGR-LVPRKGFDTIVRALPRIPDAELVIVGGPPAAE
TH_3188|M.thermoresistible__bu PQAPRGERR-RIVTVGR-FVPRKGFDTLVRALPAIPNAELVVVGGPRRSQ
MSMEG_6484|M.smegmatis_MC2_155 QR-----VSGRIIAIASADVPLKGVSHLLHAVARLRVERNLDLQLVSK--
:: :. :*. : ...
MMAR_1681|M.marinum_M --EGTQQDWLVEQARKHRVLKATKFLGHLEHAELLTLLHRADAAVFPSHY
MUL_1919|M.ulcerans_Agy99 --EGTQQDWLVEQARKHRVLKATKFLGHLEHAELLTLLHRADAAVFPSHY
Mb3058|M.bovis_AF2122/97 --EGTQQDWLIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPSHY
Rv3032|M.tuberculosis_H37Rv --EGTQQDWLIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPSHY
MLBr_01715|M.leprae_Br4923 --EGTQQDWLVDQARKYKVIKATRFVGHLNHNELLAALQRADAAVLPSHY
MAB_3366|M.abscessus_ATCC_1997 --DGTQQDWLLEQARKYKVVKSVQFLGTLDHSELLHWLHHADAILLPSHY
Mflv_3449|M.gilvum_PYR-GCK --TGPDAGHLGDVARRLRVADRVRMMRGDECPELAALLPSADVVVLPARY
Mvan_3205|M.vanbaalenii_PYR-1 --DGPDYDDILSLAREKKAAKRVNLVAGAAGDDLTTLFRSADVVVAPARY
MAV_4082|M.avium_104 LAGDEQARRLQRLAGELGVADRVRLLGGVTRAQMPALLRSADVVACTPWY
TH_3188|M.thermoresistible__bu LRTEPEARRLCTLAEELGVADRVQLYGSVARADMPAVLRSADVVACTPWY
MSMEG_6484|M.smegmatis_MC2_155 ---LEPNGPTEKLIAELGISDIVHISSGLSDQELAGLLASAEVACIPSLY
. ..: :: : *:. .. *
MMAR_1681|M.marinum_M EPFGLVALEAAAAGTPLVTSNIGGLGEAV-IDGVTGVSCPPRDVAALAAA
MUL_1919|M.ulcerans_Agy99 EPFGLVALEAAAAGTPLVTSNIGGLGEAV-IDGVTGVSCPPRDVAALAAA
Mb3058|M.bovis_AF2122/97 EPFGLVALEAAAAGTPLVTSNIGGLGEAV-INGQTGVSCAPRDVAGLAAA
Rv3032|M.tuberculosis_H37Rv EPFGLVALEAAAAGTPLVTSNIGGLGEAV-INGQTGVSCAPRDVAGLAAA
MLBr_01715|M.leprae_Br4923 EPFGLVALEAAAAGTPLVTSNIGGLGEAV-INGQTGVSCPPRDIAELAAM
MAB_3366|M.abscessus_ATCC_1997 EPFGIVALEAAAAGTPLVTSTVGGLGEAV-IDGETGMSFAPRDVAGIAEA
Mflv_3449|M.gilvum_PYR-GCK EPSSEFVLQAMACGAPVVAFAAGGARDAV-IEDVTGLLVQPGDVNALGRA
Mvan_3205|M.vanbaalenii_PYR-1 EPSCATVLQAMACGAPIVATSAGGARDAV-IGEVTGLLVPPGNADALGRA
MAV_4082|M.avium_104 EPFGIVPLEAMACGVPVVATAVGGIRDTV-VDGATGRLVPPKDPDALGEA
TH_3188|M.thermoresistible__bu EPFGIVPLEAMACGVPVVAAAVGGMLDTV-VHDVTGRLVPPRRPAELADT
MSMEG_6484|M.smegmatis_MC2_155 EGFSLPAVEAMASGTPIVASRAGALPEVVGTDGSCARLVRPADVDELTAV
* ::* *.*.*:*: *. :.* . * :
MMAR_1681|M.marinum_M VCGVLDDPAAAQQRARAARERLNSDFDWQTVAEQTAQVYLAAKRGERQPL
MUL_1919|M.ulcerans_Agy99 VCGVLDDPAAAQQRARAARERLNSNFDWQTVAEQTAQVYLAAKRGERQPL
Mb3058|M.bovis_AF2122/97 VRSVLDDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQ
Rv3032|M.tuberculosis_H37Rv VRSVLDDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQ
MLBr_01715|M.leprae_Br4923 VCTVLEDPDAAQQRALAARERLTSDFDWQTVAQQTAQVYLAAKRRERQPQ
MAB_3366|M.abscessus_ATCC_1997 VTRTLDDPAAAAERAVAARARLTADFDWATVADETAQVYLAAKRREREPL
Mflv_3449|M.gilvum_PYR-GCK VRTALSQPVLRQGMGLAGRSRARSRYSWDRIATDAEVAYLAAAARHSGQA
Mvan_3205|M.vanbaalenii_PYR-1 LRSTLGQMVLREGMGLAGRSRARSRYSWDRIATDAEVVYASATTRESAFA
MAV_4082|M.avium_104 VAALLRDGRRGRTLGEAGRERARARYSWDRVAADTERIYERLSPARRGVG
TH_3188|M.thermoresistible__bu INQLLRDSFLRQSLGAAGRDRARARYSWDRVATDTQRIYDRLVPADYRSA
MSMEG_6484|M.smegmatis_MC2_155 LGELLDSPAERRRLGAAGRQRALDVFSWESVAAQTVAVYERAQNRMGVKA
: * . . *.* * :.* :* : *
MMAR_1681|M.marinum_M PRLPIVEHALPDR-----------
MUL_1919|M.ulcerans_Agy99 PRLPIVEHALPDR-----------
Mb3058|M.bovis_AF2122/97 PRLPIVEHALPDR-----------
Rv3032|M.tuberculosis_H37Rv PRLPIVEHALPDR-----------
MLBr_01715|M.leprae_Br4923 PRLPIVEHALPDR-----------
MAB_3366|M.abscessus_ATCC_1997 GRSVIVERPLPDR-----------
Mflv_3449|M.gilvum_PYR-GCK PAGDRGPGTRGSLRPQSCSPVTRK
Mvan_3205|M.vanbaalenii_PYR-1 C-----------------------
MAV_4082|M.avium_104 TPSTRSG-----------------
TH_3188|M.thermoresistible__bu TASQMSSG----------------
MSMEG_6484|M.smegmatis_MC2_155 C-----------------------