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MKMKILLVSWEYPPVVIGGLGRHVHHLATELVAAGHEVVVLSRRPTGTDPQTHPTTDETHEGVRVIAAAE DPHEFGFGTDMMAWVLAMGHSMIRAGFGLDGWRPDIVHAHDWLVAHPAVALAQFFDVPLVSTIHATEAGR HSGWVSGSVSRQVHALESWLVRDSDSLITCSASMRDEISALFGPELAEISVIPNGIDTDGWPFAARRAHS GPAELLYFGRLEYEKGVHDAIAALPKVRRTHPGTTLTIAGDGTQLGFLTEQARRHKVLKATKFVGRVDHS QLLTLLHRADVAVLPSHYEPFGIVALEAAATGTPLVTSTAGGLGEAVIDGVTGMSYPPSDVIALAAAIRA VLDAPAAAQERATAARARLTSDFAWHTVAAETAQVYLAAKRAERRPQPRRTIVERPLPDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4262 | - | - | 100% (410) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_3449 | - | 4e-36 | 31.59% (383) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_2191 | - | 2e-28 | 29.46% (404) | glycogen synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3058 | - | 0.0 | 77.05% (414) | transferase |
| M. tuberculosis H37Rv | Rv3032 | - | 0.0 | 77.05% (414) | transferase |
| M. leprae Br4923 | MLBr_01715 | - | 0.0 | 74.64% (414) | putative transferase |
| M. abscessus ATCC 19977 | MAB_3366 | - | 1e-176 | 72.71% (414) | glycosyltransferase |
| M. marinum M | MMAR_1681 | - | 0.0 | 76.33% (414) | transferase |
| M. avium 104 | MAV_3879 | - | 0.0 | 77.75% (418) | glycosyl transferase, group 1 family protein |
| M. smegmatis MC2 155 | MSMEG_0933 | - | 5e-29 | 29.47% (397) | hypothetical protein MSMEG_0933 |
| M. thermoresistible (build 8) | TH_2191 | - | 0.0 | 76.92% (416) | POSSIBLE TRANSFERASE |
| M. ulcerans Agy99 | MUL_1919 | - | 0.0 | 76.09% (414) | transferase |
| M. vanbaalenii PYR-1 | Mvan_2096 | - | 0.0 | 87.56% (410) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4262|M.gilvum_PYR-GCK ----------------------MKMKILLVSWEYPPVVIG------GLGR
Mvan_2096|M.vanbaalenii_PYR-1 ----------------------MKTKILLVSWEYPPVVIG------GLGR
Mb3058|M.bovis_AF2122/97 ------------------------MRILMVSWEYPPVVIG------GLGR
Rv3032|M.tuberculosis_H37Rv ------------------------MRILMVSWEYPPVVIG------GLGR
MLBr_01715|M.leprae_Br4923 MFIQRHAVVRGIFGTFAPAEGTTLMKILIVSWEYPPVVIG------GLGR
MAV_3879|M.avium_104 ------------------------MKILMVSWEYPPVVIG------GLGR
MMAR_1681|M.marinum_M ------------------------MKILMVSWEYPPVVIG------GLGR
MUL_1919|M.ulcerans_Agy99 ------------------------MKILMVSWEYPPVVIG------GLGR
TH_2191|M.thermoresistible__bu ------------------------MKILMVSWEYPPVVVG------GLGR
MAB_3366|M.abscessus_ATCC_1997 ------------------------MRILMVSWEYPPVVIG------GLGR
MSMEG_0933|M.smegmatis_MC2_155 --------------MRLATDLETPRRVAVLSVHTSPLAQPGTGDAGGMNV
:: ::* . .*:. *:.
Mflv_4262|M.gilvum_PYR-GCK HVHHLATELVAAGHEVVVLSRRPTGTDPQTHPTTDETHEGVRVIAAAEDP
Mvan_2096|M.vanbaalenii_PYR-1 HVHHLATELAQSGHEVVVLSRRPTATDPQTHPTTDEVHEGVRVIAAAEDP
Mb3058|M.bovis_AF2122/97 HVHHLSTALAAAGHDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDP
Rv3032|M.tuberculosis_H37Rv HVHHLSTALAAAGHDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDP
MLBr_01715|M.leprae_Br4923 HVHHLSTALAAAGHDVVVLSRRPSGTDPCTHPTSDEISEGVRVIAAAQDP
MAV_3879|M.avium_104 HVHHLSTALAAAGHDVVVLSRRPTGTDPRTHPSTDQISEGVRVIAAAQDP
MMAR_1681|M.marinum_M HVHHLATALVAAGHEVVVLSRRPSGTDPSTHPSSDLISEGVRVIAAAQDP
MUL_1919|M.ulcerans_Agy99 HVHHLATALVAAGHEVVVLSRRPSGTDPSTHPSSDLISEGVRVIAAAQDP
TH_2191|M.thermoresistible__bu HVYHLSTALAAAGHEVVVLSRRPTGTDPSTHPSTDEVRDGVRVLAAAQDP
MAB_3366|M.abscessus_ATCC_1997 HVHHLSTELAAAGHDVVVLTRRPSGTDPSSHPTSDEISEGVRVVAAAEDP
MSMEG_0933|M.smegmatis_MC2_155 YVLQTALQLARRGVEVEVFTRATSSADAPVVP----VAPGVLVRNVVAGP
:* : : *. * :* *::* .:.:*. * ** * .. .*
Mflv_4262|M.gilvum_PYR-GCK HEFGFGTDMMAWVLAMGHSMIRAGFG----------LDGWRPDIVHAHDW
Mvan_2096|M.vanbaalenii_PYR-1 HEFTFGTDMMAWTLAMGHAMIRAGLV----------LADWRPDIVHAHDW
Mb3058|M.bovis_AF2122/97 HEFTFGNDMMAWTLAMGHAMIRAGLR----LKKLGTDRSWRPDVVHAHDW
Rv3032|M.tuberculosis_H37Rv HEFTFGNDMMAWTLAMGHAMIRAGLR----LKKLGTDRSWRPDVVHAHDW
MLBr_01715|M.leprae_Br4923 HEFTFSNDMMAWTLAMGHAMIRTGLS----LTRHSSDLPWRPDVVHAHDW
MAV_3879|M.avium_104 HEFTFGTDMMAWTLAMGHAMIRAGLPPKLHDKKPGGNRPWRPDVVHAHDW
MMAR_1681|M.marinum_M HEFSFGSDMMAWTLAMGHAMVRAGLT----LSGPGAEQPWQPDIVHAHDW
MUL_1919|M.ulcerans_Agy99 HEFSFGSDMMAWTLAMGHAMVRAGLT----LSGPGAEQPWQPDIVHAHDW
TH_2191|M.thermoresistible__bu HEFDFGRDMMAWTLAMGHSMVRAGLALG--LRGGTGGTPWQPDVVHAHDW
MAB_3366|M.abscessus_ATCC_1997 HDFDFGTDMMAWTLAMGHAMVRAGLALG-----LKGSGDWRPDVVHAHDW
MSMEG_0933|M.smegmatis_MC2_155 FEGLDKNDLPTQLCAFTAGVLRAEAT----------HEPGYYDVVHSHYW
.: *: : *: .::*: *:**:* *
Mflv_4262|M.gilvum_PYR-GCK LVAHPAVALAQFFDVPLVSTIHATEAGRHSGWVSGSVSR--QVHALESWL
Mvan_2096|M.vanbaalenii_PYR-1 LVATPAVALAQFFDVPLVSTIHATEAGRHSGWVSGQVSR--QVHALESWL
Mb3058|M.bovis_AF2122/97 LVAHPAIALAQFYDVPMVSTIHATEAGRHSGWVSGALSR--QVHAVESWL
Rv3032|M.tuberculosis_H37Rv LVAHPAIALAQFYDVPMVSTIHATEAGRHSGWVSGALSR--QVHAVESWL
MLBr_01715|M.leprae_Br4923 LVAHPAITLAQFYDVPMVSTIHATEAGRHSGWVSGALSR--QVHAVESWL
MAV_3879|M.avium_104 LVAHPAIALAQFYDVPMVSTIHATEAGRHSGWVSGPISR--QVHAIESWL
MMAR_1681|M.marinum_M LVAHPAIALADYYDVPMVSTIHATEAGRHSGWVSGDLSR--QVHAVESWL
MUL_1919|M.ulcerans_Agy99 LVAHPAIALADYYDVPMVSTIHATEAGRHSGWVSGDLSR--QVHAVESWL
TH_2191|M.thermoresistible__bu LVAHPAIALAEFFDVPLVSTIHATEAGRHSGWVSGPISR--QVHAVESWL
MAB_3366|M.abscessus_ATCC_1997 LVAHPAIALAEHFDVPLVSTLHATEAGRHSGWVSGRISR--QVHSVEWWL
MSMEG_0933|M.smegmatis_MC2_155 LSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAAGDAPEPPLRAVGEQQV
* . . : : **:* * *: * :::. .:* .. * :
Mflv_4262|M.gilvum_PYR-GCK VRDSDSLITCSASMRDEISALFGPELAEISVIPNGIDTDGWPFAARRAHS
Mvan_2096|M.vanbaalenii_PYR-1 VRDSDSLITCSASMRDEITTLFGPELADITVIPNGIDTDGWPFAPHRPRP
Mb3058|M.bovis_AF2122/97 VRESDSLITCSASMNDEITELFGPGLAEITVIRNGIDAARWPFAARRPRT
Rv3032|M.tuberculosis_H37Rv VRESDSLITCSASMNDEITELFGPGLAEITVIRNGIDAARWPFAARRPRT
MLBr_01715|M.leprae_Br4923 VRESDSLITCSASMCNEIIELFGPGLAEITVIRNGIDPARWPFAARRART
MAV_3879|M.avium_104 VRESDSLITCSASMADEITELFGPGLAQITVIRNGIETARWPFAPRRPRT
MMAR_1681|M.marinum_M VRESDSLITCSGSMSDEITELFGPGLAETAVIRNGIDAARWPFAVRKPRT
MUL_1919|M.ulcerans_Agy99 VRESDSLITCSGSMSDEITELFGPGLAETAVIRNGIDVARWPFAVRKPRT
TH_2191|M.thermoresistible__bu VRDSDSLITCSASMSEEITELFGPGLSEIRVIRNGIDVAQWPFARRSPRS
MAB_3366|M.abscessus_ATCC_1997 ARESDSLITCSASMLDEVTQLFGPELPQVHVIRNGIDVTRWVFAPRPPAD
MSMEG_0933|M.smegmatis_MC2_155 VDEADRLIVNTEVEAQQLVSLHNADRSRIDVVHPGVDLDVFTPGSRDAAR
. ::* **. : ::: *... . *: *:: : . : .
Mflv_4262|M.gilvum_PYR-GCK G-------PAELLYFGRLEYEKGVHDAIAALPKVRRTHPGTTLTIAGDG-
Mvan_2096|M.vanbaalenii_PYR-1 G-------PAELLYFGRLEYEKGVHDLIAALPRIRRAHPGTTLTIAGDG-
Mb3058|M.bovis_AF2122/97 G-------PAELLYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGEG-
Rv3032|M.tuberculosis_H37Rv G-------PAELLYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGEG-
MLBr_01715|M.leprae_Br4923 G-------PAELLYVGRLEYEKGVHDVIAALPRIRRSYPGTTLTIAGEG-
MAV_3879|M.avium_104 G-------PAELLYLGRLEYEKGVHDVIAALPRIRRTHPGTTLTIAGEG-
MMAR_1681|M.marinum_M G-------PPELLYVGRLEYEKGVHNAIAALPRIRRAHPGTTLTIAGEG-
MUL_1919|M.ulcerans_Agy99 G-------PPELLYVGRLEYEKGVHNAIAALPRIRRAHPGTTLTIAGEG-
TH_2191|M.thermoresistible__bu G-------PPRLLYVGRLEYEKGVQDAIAALPRIRRTHPGTTLTIAGTG-
MAB_3366|M.abscessus_ATCC_1997 GT------PPVLLFVGRLEYEKGIHDAIAALPKIRRAHPGTVLAVAGDG-
MSMEG_0933|M.smegmatis_MC2_155 AVFGLPTDQKIVAFVGRIQPLKAPDILLRAAAKLPGVRVLIAGGPSGSGL
. : :.**:: *. . : * .:: . :* *
Mflv_4262|M.gilvum_PYR-GCK TQLGFLTEQARRHKVLKATKFVGRVDHSQLLTLLHRADVAVLPSHYEPFG
Mvan_2096|M.vanbaalenii_PYR-1 TQLDFLVEQARKHKVVKATNFIGRVGHSELLRLLHRADAAVLPSHYEPFG
Mb3058|M.bovis_AF2122/97 TQQDWLIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPSHYEPFG
Rv3032|M.tuberculosis_H37Rv TQQDWLIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPSHYEPFG
MLBr_01715|M.leprae_Br4923 TQQDWLVDQARKYKVIKATRFVGHLNHNELLAALQRADAAVLPSHYEPFG
MAV_3879|M.avium_104 TQQGWLIEQARKHRVLKAIRFVGHLEHSELLAMLHRADAAVLPSHYEPFG
MMAR_1681|M.marinum_M TQQDWLVEQARKHRVLKATKFLGHLEHAELLTLLHRADAAVFPSHYEPFG
MUL_1919|M.ulcerans_Agy99 TQQDWLVEQARKHRVLKATKFLGHLEHAELLTLLHRADAAVFPSHYEPFG
TH_2191|M.thermoresistible__bu TQHEWLVEQARKHKVLKATRFVGQLGHEALLRQLHTADAAVLPSHYEPFG
MAB_3366|M.abscessus_ATCC_1997 TQQDWLLEQARKYKVVKSVQFLGTLDHSELLHWLHHADAILLPSHYEPFG
MSMEG_0933|M.smegmatis_MC2_155 AQPDTLVRLADELGISDRVTFLPPQSREQLVNVYRAADLVAVPSYSESFG
:* * * . : *: : *: : ** .**: *.**
Mflv_4262|M.gilvum_PYR-GCK IVALEAAATGTPLVTSTAGGLGEAVIDGVTGMSYPPSDVIALAAAIRAVL
Mvan_2096|M.vanbaalenii_PYR-1 IVALEAAATGTPLVTSTAGGLGEAVIDGVTGLSYPPGDVAALARAVRAVL
Mb3058|M.bovis_AF2122/97 LVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVL
Rv3032|M.tuberculosis_H37Rv LVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVL
MLBr_01715|M.leprae_Br4923 LVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCPPRDIAELAAMVCTVL
MAV_3879|M.avium_104 IVALEAAAAGTPLVTSNIGGLGEAVIDGQTGVSCPPRDVPALAAAIRTVL
MMAR_1681|M.marinum_M LVALEAAAAGTPLVTSNIGGLGEAVIDGVTGVSCPPRDVAALAAAVCGVL
MUL_1919|M.ulcerans_Agy99 LVALEAAAAGTPLVTSNIGGLGEAVIDGVTGVSCPPRDVAALAAAVCGVL
TH_2191|M.thermoresistible__bu IVALEAAATGAPLVTSTAGGLGEAVIDGVTGKSFKPRDIAGLTAAVRAVL
MAB_3366|M.abscessus_ATCC_1997 IVALEAAAAGTPLVTSTVGGLGEAVIDGETGMSFAPRDVAGIAEAVTRTL
MSMEG_0933|M.smegmatis_MC2_155 LVAVEAQACGTPVVAAAVGGLPVAVADGVSGALVDGHDIGDWADTISEVL
:**:** * *:*:*:: *** ** :* :* *: : : .*
Mflv_4262|M.gilvum_PYR-GCK DAPAAAQERATAARARLTSDFAWHTVAAETAQVYLAAK--RAERRPQPRR
Mvan_2096|M.vanbaalenii_PYR-1 DSPAAAQRRARAARERLTSDFSWHTVAAETAQVYLAAK--RAVRRPQPRR
Mb3058|M.bovis_AF2122/97 DDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAK--RGERQPQPRL
Rv3032|M.tuberculosis_H37Rv DDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAK--RGERQPQPRL
MLBr_01715|M.leprae_Br4923 EDPDAAQQRALAARERLTSDFDWQTVAQQTAQVYLAAK--RRERQPQPRL
MAV_3879|M.avium_104 DDPEAAQRRACAARERLTSDFDWHTVADKTAQVYLSAK--RAERQPQARL
MMAR_1681|M.marinum_M DDPAAAQQRARAARERLNSDFDWQTVAEQTAQVYLAAK--RGERQPLPRL
MUL_1919|M.ulcerans_Agy99 DDPAAAQQRARAARERLNSNFDWQTVAEQTAQVYLAAK--RGERQPLPRL
TH_2191|M.thermoresistible__bu DDPEGAQQRAVAARERLTADFDWHSVAAETAQVYLAAK--RREREPLPRR
MAB_3366|M.abscessus_ATCC_1997 DDPAAAAERAVAARARLTADFDWATVADETAQVYLAAK--RREREPLGRS
MSMEG_0933|M.smegmatis_MC2_155 DREPAALSRASAEHA---AQFSWAHTVDALLASYSRAMSDYRARHPRPAA
: .* ** * : ::* * .. * * *.*
Mflv_4262|M.gilvum_PYR-GCK TIVERPLPDR-----
Mvan_2096|M.vanbaalenii_PYR-1 PIEERPLPDR-----
Mb3058|M.bovis_AF2122/97 PIVEHALPDR-----
Rv3032|M.tuberculosis_H37Rv PIVEHALPDR-----
MLBr_01715|M.leprae_Br4923 PIVEHALPDR-----
MAV_3879|M.avium_104 PIVEHALPDR-----
MMAR_1681|M.marinum_M PIVEHALPDR-----
MUL_1919|M.ulcerans_Agy99 PIVEHALPDR-----
TH_2191|M.thermoresistible__bu LIVEHALPDR-----
MAB_3366|M.abscessus_ATCC_1997 VIVERPLPDR-----
MSMEG_0933|M.smegmatis_MC2_155 RRSGRRFSMRRGVRT
: :. *