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M. gilvum PYR-GCK Mflv_1057 (-)

annotation: hypothetical protein Mflv_1057
coordinates: 1100638 - 1102341
length: 567

VRVLHLGADTPKPSPHQPKTLLNSRNAPTRTLGAPHVFEGWSDLRVLSGVQGPYRQIAAAMAASLAGIAE
LLDRRTAEELDAALHVRSVITAFDRTAVEVGAALALPSPKARELVRQADALHTRLPGLGALLAAGEVDYD
TVAMVLDRTDLVHEDVMAQLEAALLERVRGWACFSRKQLRDEVDALVKEVDADAVKQRRTRAYDQRRVSV
AAEADGMAVVRGTMSAEDGAALDTRLTAIAKKVCACDPRSLVQRRADAFKALTLGEPFGCMCGRNDCPDA
LAATPAGSTPAAPPQQSLPMGRQVVLNVIASAETVTGLGNAAGYLLGYGVIDAELVRELARDATRRLVEA
PRFEERQALTYRPSDALARFIRARDLTCRFPGCTVPATRCDIDHTTPFDHEDPAAGGWTVPWNLACYCRE
HHRHKTFDTGWRDQQLVDGTIIWTAPTGHEYRTVPAGVGLFPGLGRARNSAERRRVAAARQRLHRHRDAS
TYNRYRNQQARDEVRNRRWRNGFRGRYLLFKGEFAHNAPSRSPFGRFVNDPFEPESLPPDWHPPPQDRAD
PDEPPPF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1057--100% (567)hypothetical protein Mflv_1057
M. gilvum PYR-GCKMflv_0946-0.098.35% (484) hypothetical protein Mflv_0946
M. gilvum PYR-GCKMflv_3596-5e-6936.54% (468) hypothetical protein Mflv_3596

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0528-5e-7438.75% (511) 13E12 repeat family protein
M. tuberculosis H37RvRv0515-5e-7438.75% (511) 13E12 repeat family protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4752-7e-6737.42% (465) hypothetical protein MAB_4752
M. marinum MMMAR_1213-7e-7538.20% (534) 13e12 repeat-containing protein
M. avium 104MAV_0536-1e-11344.20% (543) hypothetical protein MAV_0536
M. smegmatis MC2 155MSMEG_5026-2e-7036.92% (493) hypothetical protein MSMEG_5026
M. thermoresistible (build 8)TH_0334-5e-5337.02% (389) HNH endonuclease
M. ulcerans Agy99MUL_2679-4e-7241.27% (424) 13e12 repeat-containing protein
M. vanbaalenii PYR-1Mvan_3778-7e-7138.35% (485) hypothetical protein Mvan_3778

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_5026|M.smegmatis_MC2_155      ----------------------------MGAGILERMFDGTS--------
Mvan_3778|M.vanbaalenii_PYR-1       ------------------------------------MFAYAE--------
TH_0334|M.thermoresistible__bu      ------------------------------------MFESLD--------
Mb0528|M.bovis_AF2122/97            ----------------------------MPSPEAIAHFDERFECHAPRTT
Rv0515|M.tuberculosis_H37Rv         ----------------------------MPSPEAIAHFDERFECHAPRTT
MMAR_1213|M.marinum_M               --------------------------MRAQALRPTVSVDQHMIEHVFDTD
MUL_2679|M.ulcerans_Agy99           -------------------------------------MDQHIIEYVFDTD
MAB_4752|M.abscessus_ATCC_1997      ------------------------------------MFDELG--------
Mflv_1057|M.gilvum_PYR-GCK          MRVLHLGADTPKPSPHQPKTLLNSRNAPTRTLGAPHVFEGWSD-------
MAV_0536|M.avium_104                ------------------------------------MFESSPD-------
                                                                         .            

MSMEG_5026|M.smegmatis_MC2_155      --DAGLIDAIAEAKRQENAATARRLFAIGELDT-R-RA-IDLAECNFWRT
Mvan_3778|M.vanbaalenii_PYR-1       --PAELIDAMSSAARAESAAIARRLEAVAALFR-S-RK-CDYAEAGFLHT
TH_0334|M.thermoresistible__bu      --DGAVVDSIAAASREQSAACGREMLAIGELYA-R-RAPEDDTERANWAI
Mb0528|M.bovis_AF2122/97            RVSAAFIDRICSATRAENRAAAAQLVALGELFA---YRWSRCGGREEWVM
Rv0515|M.tuberculosis_H37Rv         RVSAAFIDRICSATRAENRAAAAQLVALGELFA---YRWSRCGGREEWVM
MMAR_1213|M.marinum_M               --SSAPLTRITAAARAEARAAAERLAAIGDLFR---LRLSQHGNREDWVA
MUL_2679|M.ulcerans_Agy99           --DSAPLTRITAAARAEARAAAERLAAIGDLFR---LRLSQHGNREDWVA
MAB_4752|M.abscessus_ATCC_1997      --DVELIDLIASAQRAEAQACARKLDAIGVLVDRH-ADLGKPDERDHHAL
Mflv_1057|M.gilvum_PYR-GCK          --LRVLSGVQG-PYRQIAAAMAASLAGIAELLDRRTAEELDAALHVRSVI
MAV_0536|M.avium_104                --PAALVAVIESTHREESMLVARRFAAVAALLRHR-VATADRPEPEYAEI
                                                . *      .  : .:. *                   

MSMEG_5026|M.smegmatis_MC2_155      DPFEEVCAEVSAALRISRSRANWQVHLARVLRDRIPKVAAVFAQGDIDFR
Mvan_3778|M.vanbaalenii_PYR-1       DVYEAVAAEVSAAQNISRSRAGYQVEMAVSLYTRLPKVAEAFARGDIDLR
TH_0334|M.thermoresistible__bu      DGHANVVAEISAALNISRGRAAGRLQLAIDLRERLPRVAAVFAAGDIDFR
Mb0528|M.bovis_AF2122/97            DTMAAVAAEVAAALRISQGLAASRLRYARAMRERLPKTAEVFSAGDIGYL
Rv0515|M.tuberculosis_H37Rv         DTMAAVAAEVAAALRISQGLAASRLRYARAMRERLPKTAEVFSAGDIGYL
MMAR_1213|M.marinum_M               DTCDAVAAEVAAALNTSVAMGHSNLRYARAMRERLPQLGAEFRAGGIDFR
MUL_2679|M.ulcerans_Agy99           DTCDAVAAEVAAALNTSVAMGHSNLRYARAMRERLPQLGAEFRAGGIDFR
MAB_4752|M.abscessus_ATCC_1997      DRWDRVASEVAAAQGITHALASSQMRYAQVLRHRLRAVAERFAAGDLDFR
Mflv_1057|M.gilvum_PYR-GCK          TAFDRTAVEVGAALALPSPKARELVRQADALHTRLPGLGALLAAGEVDYD
MAV_0536|M.avium_104                DGFEQTAAEVAAAMNLSAAAASYLVSYAETLDTRLPEVAALLAEGRTDWR
                                         .  *:.**   .   .   :  *  :  *:   .  :  *  .  

MSMEG_5026|M.smegmatis_MC2_155      IVTKIATRT-ELVDPAAMPALDDVLARRCPNWMRLSEPKLEERIDQCILR
Mvan_3778|M.vanbaalenii_PYR-1       MVQIVLART-KNVEDDVIGGLDKAIAPKLSRWMRLSKNDLRDRVDLWVAD
TH_0334|M.thermoresistible__bu      MVSALVNRSRNVVDPDLLARLDAALAAWSPKWMKLSGPTLNERIDMWVER
Mb0528|M.bovis_AF2122/97            MFATIVYRTDLIVDPDVLAAVDAQLAANVARWPSMTKARLAGQVDKIVAR
Rv0515|M.tuberculosis_H37Rv         MFATIVYRTDLIVDPDVLAAVDAQLAANVARWPSMTKARLAGQVDKIVAR
MMAR_1213|M.marinum_M               LFRTIVFRTDLITDSDALAAVDARLAIKAPRWPSMTSWKLATEVDRVVAK
MUL_2679|M.ulcerans_Agy99           LFRTIVFRTDLITESDALAAVDARLAIKAPRWPSMTSWKLATEVDRVVAK
MAB_4752|M.abscessus_ATCC_1997      TVALIINRTELVDDEAVVARVDAAIVRALPRWARWSHKRITAALDALVLH
Mflv_1057|M.gilvum_PYR-GCK          TVAMVLDRTDLVH-EDVMAQLEAALLERVRGWACFSRKQLRDEVDALVKE
MAV_0536|M.avium_104                TVRLIITRTSLVTDAELIAKLDRSLAARIGNWHGWSRQRIVNAVDAAVRT
                                     .  :  *:        :  ::  :      *   :   :   :*  :  

MSMEG_5026|M.smegmatis_MC2_155      LDPDGQRVTKRSE-DSRYFTVQPADTPG--MANAQGYLPAHDAAGFDKRL
Mvan_3778|M.vanbaalenii_PYR-1       FDPAAVRVPPEAK-DNRYFDVTP-DVPG--MAFAGGLLNARDAAALDQRL
TH_0334|M.thermoresistible__bu      FDPTGVREPRSPG-EDRYVVVTP-AGQG--MVDVSARLTFEAGFAFXTRL
Mb0528|M.bovis_AF2122/97            ADADAVRRRKEYQ-AQRQFWVGE-SQDG--VCQIGGSLLAVDAHALDARL
Rv0515|M.tuberculosis_H37Rv         ADADAVRRRKEYQ-AQRQFWVGE-SQDG--VCQIGGSLLAVDAHALDARL
MMAR_1213|M.marinum_M               FDRDAVRRSRRDA-ADRYVDCAP-LEPG--MALVNGQVFAATAEALARRL
MUL_2679|M.ulcerans_Agy99           FDRDAVRRSRRDA-ADRYVDCAP-LEPG--MALVNRQVFSATAEALARRL
MAB_4752|M.abscessus_ATCC_1997      FDQDAVRRNRSAT-DKRHLEIRP-LGNGEPVAEVWGTLQAVHAVALDKRL
Mflv_1057|M.gilvum_PYR-GCK          VDADAVKQRRTRAYDQRRVSVAA-EADG--MAVVRGTMSAEDGAALDTRL
MAV_0536|M.avium_104                ADPDAARERRLAAEEDRHIGISA-AENG--MAEVHGSVAAAAATAFDRRL
                                     *  . :        .* .        *  :      :    . .:  **

MSMEG_5026|M.smegmatis_MC2_155      DAIAATVCPNDPRTPDQRRADALGALGRYRDTLDCQCGREDCTAVAERD-
Mvan_3778|M.vanbaalenii_PYR-1       EAIAATVCSNDPRSHNNLRADAAGALGRGESTLTCECGAEDCPAAVLRE-
TH_0334|M.thermoresistible__bu      DQIAATVCRDDPRTADQRRADAMAAMSEGQNRLVCGCGSEDCPADPADT-
Mb0528|M.bovis_AF2122/97            SALAGTVCEHDPRSREQRRADALGALAGGADRLGCGCGRADCAAGKRPA-
Rv0515|M.tuberculosis_H37Rv         SALAGTVCEHDPRSREQRRADALGALAGGADRLGCGCGRADCAAGKRPA-
MMAR_1213|M.marinum_M               DELAKTVCADDPRTVVQRRADALGTLAAGQDRLICDCGRTDCPAAGAPQ-
MUL_2679|M.ulcerans_Agy99           DELAKTVCADDPRTVVQRRADALGTLAAGQDRLICDCGRTDCPAAGAPQ-
MAB_4752|M.abscessus_ATCC_1997      DLLAGTVCPADPRSKTQRRADAVGALTQGLNRMRCACGHPDCSG--RDT-
Mflv_1057|M.gilvum_PYR-GCK          TAIAKKVCACDPRSLVQRRADAFKALTLGE-PFGCMCGRNDCPDALAATP
MAV_0536|M.avium_104                SQLAKQVCPADPRTLDQRRADALAALAEGR-RLPCACGQPDCPARTGNQN
                                      :*  **  ***:  : ****  ::      : * **  **.       

MSMEG_5026|M.smegmatis_MC2_155      --------------AVNNAMIHVLAEQSTLDG-GNEPG-YLPGFGMLPAH
Mvan_3778|M.vanbaalenii_PYR-1       --------------SAAQVVIHILAEQATVDGDGDKAG-YLPGFGVLPAE
TH_0334|M.thermoresistible__bu      --------------AATRLVINVIAEQATVEGRSDNPG-YLPGYGAVPAS
Mb0528|M.bovis_AF2122/97            --------------APP-VVIHLIAEAATINGTGSAPASQMNADGLITAE
Rv0515|M.tuberculosis_H37Rv         --------------APP-VVIHLIAEAATINGTGSAPASQMNADGLITAE
MMAR_1213|M.marinum_M               --------------QPSRVVIHVVAGRETVDGAGEAPG-VLPGDGIIPAE
MUL_2679|M.ulcerans_Agy99           --------------QPSRVVIHVVAGCQTVDGAGEAPG-VLPGDGIIPAE
MAB_4752|M.abscessus_ATCC_1997      --------------ADVPVVVNVVINQSTLAGSDDCPA-HVPGFGVLAAE
Mflv_1057|M.gilvum_PYR-GCK          AGSTPAAPPQQSLPMGRQVVLNVIASAETVTGLGNAAG-YLLGYGVIDAE
MAV_0536|M.avium_104                ADDR----------TGARVVINVVASDRTVYADGAEPG-YLEGYGVIDAD
                                                       :::::    *: . .  ..  : . * : * 

MSMEG_5026|M.smegmatis_MC2_155      MVREVAKTATTKPVTIPK--DKAQSGYRPNAELTEFIRWRDLTCRFPGCD
Mvan_3778|M.vanbaalenii_PYR-1       EVRAAAKTAKLKPVRLPG--AEPEKGYRPSAGLKDFLQWRDLTCRFPGCD
TH_0334|M.thermoresistible__bu      ILRAKAATATLRPVALPQ--PCAEAGYRPSAALTRFIRCRDLTCRFPGCD
Mb0528|M.bovis_AF2122/97            LVAELAKTATLVPLVHPGD-APPEPGYAPSKALADFVRCRDLTCRWPGCD
Rv0515|M.tuberculosis_H37Rv         LVAELAKTATLVPLVHPGD-APPEPGYAPSKALADFVRCRDLTCRWPGCD
MMAR_1213|M.marinum_M               IVRELAKSAKLQPMSTP---ILAETGYVPSPALMDFVRARDLTCRAPGCD
MUL_2679|M.ulcerans_Agy99           IVRELAKSAKLQPMSTP---ILAETGYVPSPALMDFVRARDLTCRAPGCD
MAB_4752|M.abscessus_ATCC_1997      SARAAVAGTPTRNLTDS-----RSTGYRPSAKLAAFVRSRDQLCRFPGCE
Mflv_1057|M.gilvum_PYR-GCK          LVRELARDATRRLVEAPRFEERQALTYRPSDALARFIRARDLTCRFPGCT
MAV_0536|M.avium_104                QVRRLA-AAAHLLVANPATSPAAALRYQPSAALERAVRCRDLTCRFPGCS
                                         .  :    :  .         * *.  *   :: **  ** *** 

MSMEG_5026|M.smegmatis_MC2_155      APAMAADIDHTRPY-----PQG-PTHPSNTKLYCRTHHLIKTFYTGPNGW
Mvan_3778|M.vanbaalenii_PYR-1       APVERCDVDHTTRW-----PFG-VTHASGLKHYCRTHHVIKTFLTGVYGW
TH_0334|M.thermoresistible__bu      APAAVCQIDHTIPY-----PAG-PTHPSNLKLLCVFHCRQAELR-----F
Mb0528|M.bovis_AF2122/97            EPATNCDLDHTIPY-----AAGGPTHASNLKCYCRTHHLVKTFWG----W
Rv0515|M.tuberculosis_H37Rv         EPATNCDLDHTIPY-----AAGGPTHASNLKCYCRTHHLVKTFWG----W
MMAR_1213|M.marinum_M               RPATQCDVDHTIPY-----SDGGATHPSNLKCLCRKHHLLKTFWG----W
MUL_2679|M.ulcerans_Agy99           RPATQCDVDHTIPY-----SDGGATHPSNLKCLCRKHHLLKTFWG----W
MAB_4752|M.abscessus_ATCC_1997      AVADRADIDHTVPW-----ATGGPTTGANLKALCRKHHLLKTFGQ----W
Mflv_1057|M.gilvum_PYR-GCK          VPATRCDIDHTTPFDHEDPAAGGWTVPWNLACYCREHHRHKTFDT---GW
MAV_0536|M.avium_104                RPAVICDLDHSVPFNHQNPVAGGWTVLENLKCLCRQHHRLKTFG----GW
                                      .  .::**:  :       *  *   .    *  *     :      :

MSMEG_5026|M.smegmatis_MC2_155      TDRQLPDGTIEFTAPTGHIYTTEPQGAALFPVLGTPTGELNLPPQQD--E
Mvan_3778|M.vanbaalenii_PYR-1       RDEQRRDGTVVLTAPTGHVYTTEPLGGLLFPTLATPTAPL-PDVEVP--E
TH_0334|M.thermoresistible__bu      THDQHKHQSSCLPA-----YFQRPHG----PATRRP--------------
Mb0528|M.bovis_AF2122/97            RDQQLPDGTLILTSPSGHTYVSTPGSALLFPSLCHFSGGIPAPEADPPYD
Rv0515|M.tuberculosis_H37Rv         RDQQLPDGTLILTSPSGHTYVSTPGSALLFPSLCHFSGGIPAPEADPPYD
MMAR_1213|M.marinum_M               HDKQLPDATVIWSLPDGQTYVTTPGSAWLLPGLFAPSPELPPPARKP-QD
MUL_2679|M.ulcerans_Agy99           HDEQLPDATVIWSLPDGQTYVTTPGSAWLLPGLFAPSPELPPPPR-----
MAB_4752|M.abscessus_ATCC_1997      TELQEPDGTVIWKSPTGHRYATTPVSWFLFPALTRHH-------------
Mflv_1057|M.gilvum_PYR-GCK          RDQQLVDGTIIWTAPTGHEYRTVPAGVGLFPG-LGRARNSAERRRVAAAR
MAV_0536|M.avium_104                RDRQLADGTVVWTSPTGRAYRTSPAGADLFAQPRGPARAAPTPNRRSRSK
                                     . *  . :          *   * .    .                   

MSMEG_5026|M.smegmatis_MC2_155      PHPNRGVMMPKRRQ----------TREQDRADRINAERRERAELNAEQ--
Mvan_3778|M.vanbaalenii_PYR-1       DDPDKAAMMPRRR-----------TREQERRARIARERRQRIEINAER--
TH_0334|M.thermoresistible__bu      ---------PSARG----------LREAVPRQGVDPRR-----VSGQ---
Mb0528|M.bovis_AF2122/97            HCDQRTAMMPKRRR----------TRAQDRAYRIATERRQNHAARQRAQV
Rv0515|M.tuberculosis_H37Rv         HCDQRTAMMPKRRR----------TRAQDRAYRIATERRQNHAARQRAQV
MMAR_1213|M.marinum_M               HCGNRDAMMPKRAR----------TRAQSSAARIAAERNHNMTSRQARRR
MUL_2679|M.ulcerans_Agy99           --------------------------SEATGSLRKPRRDDAQTRPNSRPK
MAB_4752|M.abscessus_ATCC_1997      ------------------------TRQQARDRRRRTERNLNREQR-----
Mflv_1057|M.gilvum_PYR-GCK          QRLHRHRDASTYN---------RYRNQQAR-DEVRNRRWRNGFRGRYLLF
MAV_0536|M.avium_104                QRNGRIMRARKHNREQRPINEARIRLEQARQREIADRKFRNHMRDMLFLF
                                                                        .:            

MSMEG_5026|M.smegmatis_MC2_155      -------QRQRQAWLADNYEP-----------------------PPF
Mvan_3778|M.vanbaalenii_PYR-1       -------ERQHQAWLAATYEP-----------------------PPF
TH_0334|M.thermoresistible__bu      -----------------------------------------------
Mb0528|M.bovis_AF2122/97            LTQTAAATDTHGPPPDHNDDP-----------------------PPF
Rv0515|M.tuberculosis_H37Rv         LTQTAAATDTHGPPPDHNDDP-----------------------PPF
MMAR_1213|M.marinum_M               RWEECYFGPRDASASDDEEPP-----------------------PF-
MUL_2679|M.ulcerans_Agy99           ------LGRTHCDRTQPQHD---------------------------
MAB_4752|M.abscessus_ATCC_1997      ------LQREAALAALAAKDP-----------------------PPF
Mflv_1057|M.gilvum_PYR-GCK          KGEFAHNAPSRSPFGRFVNDPFEPESLPPDWHPPPQDRADPDEPPPF
MAV_0536|M.avium_104                KG-----APSTSPFCAWVNDPREPEELPPDWVPDEPAYQPLPDDPPF