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MNSPLRKALIAAGGTTVLMLAVGCGGSDGREETTTSTTTESSVTTTTTTAPSTPETTMAPETTGAPAPGD PSQPGGGGSIPGGPTGSGGPEGGGGSIPGGPTGSGGPDGGGGSIPGGPTITGGPGGGSGSIPGGPTINIP VP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_4416 | - | - | 100% (142) | hypothetical protein Mflv_4416 |
M. gilvum PYR-GCK | Mflv_1054 | - | 5e-19 | 47.83% (92) | hypothetical protein Mflv_1054 |
M. gilvum PYR-GCK | Mflv_4039 | infB | 2e-10 | 42.86% (84) | translation initiation factor IF-2 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0767 | PE_PGRS9 | 1e-10 | 32.31% (130) | PE-PGRS family protein |
M. tuberculosis H37Rv | Rv3514 | PE_PGRS57 | 2e-10 | 51.39% (72) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 5e-09 | 39.77% (88) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_3220 | - | 7e-34 | 53.62% (138) | hypothetical protein MAB_3220 |
M. marinum M | MMAR_2823 | - | 6e-36 | 54.81% (135) | PE-PGRS family protein |
M. avium 104 | MAV_2780 | - | 3e-37 | 60.33% (121) | hypothetical protein MAV_2780 |
M. smegmatis MC2 155 | MSMEG_5543 | - | 1e-21 | 59.21% (76) | hypothetical protein MSMEG_5543 |
M. thermoresistible (build 8) | TH_3373 | - | 2e-06 | 32.69% (104) | PUTATIVE hypothetical protein Mjls_1192 |
M. ulcerans Agy99 | MUL_0637 | - | 9e-12 | 40.20% (102) | hypothetical protein MUL_0637 |
M. vanbaalenii PYR-1 | Mvan_2314 | infB | 3e-11 | 42.86% (84) | translation initiation factor IF-2 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2823|M.marinum_M -----------------------------------------------MRS MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 ------------------------MQDSRQRKKQDQRSPTHLTREHPMKT Mb0767|M.bovis_AF2122/97 ----MSFVLAMPEVLGSAATDLAALGSVLGAADAAAAATTTGIVAAVQDE Rv3514|M.tuberculosis_H37Rv ----MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADE MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRES Mvan_2314|M.vanbaalenii_PYR-1 MAGKARVHELAKELGVTSKEVLARLSEQGEFVKSASSTVEAPVARRLRES Mflv_4416|M.gilvum_PYR-GCK -----------------------------------------------MNS MUL_0637|M.ulcerans_Agy99 -----------MLVAGWPAEGEPQMDVVLGVAIAGPIARLALVGAAAEGS TH_3373|M.thermoresistible__bu ------------------------MADFGRWNPNWNPDDGGQPSLQDIHR MMAR_2823|M.marinum_M QARTTFAVFGG---------------GAMLVLA--VACGGGENKGPSS-- MAV_2780|M.avium_104 -------MFGG---------------AAMLVLA--VGCGGGHKGGPS--- MAB_3220|M.abscessus_ATCC_1997 RTVKPAKVFAG---------------CAIALGAALAGCGTNNDGGPTS-- Mb0767|M.bovis_AF2122/97 VSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSAGAGAYASAEAAGAA Rv3514|M.tuberculosis_H37Rv VSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAAAAE MSMEG_5543|M.smegmatis_MC2_155 ----------------------------------------MAMAEPA--- MLBr_01556|M.leprae_Br4923 FGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP Mvan_2314|M.vanbaalenii_PYR-1 YGGSKSDKTKAAPSGNGAAGATVKPSAPQSRPGPKPGPPVAQQPAAPAAP Mflv_4416|M.gilvum_PYR-GCK PLRKALIAAGG-----------------TTVLMLAVGCGGSDGREETTTS MUL_0637|M.ulcerans_Agy99 AVIDQSSVDLAEGPVAVLTETIVGTNQLLADEGHHLVATRLCWSDQDR-- TH_3373|M.thermoresistible__bu SEQFIEALSTG-----------------RPVYANDPGEDELAYLMAGWRD MMAR_2823|M.marinum_M ----------------------------------------------TTPT MAV_2780|M.avium_104 ----------------------------------------------TTST MAB_3220|M.abscessus_ATCC_1997 ----------------------------------------------TSTT Mb0767|M.bovis_AF2122/97 VLAN-----PAQSVQQDLLAAVNAQSVALTGR-----PLIGNG---ANGA Rv3514|M.tuberculosis_H37Rv QIVLGVINAPTQALLGRPLIGDGANATTPGGAGGAGGLLFGNGGAGAAGA MSMEG_5543|M.smegmatis_MC2_155 ---------PPPCVN-------------------------------ADGT MLBr_01556|M.leprae_Br4923 VQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAA Mvan_2314|M.vanbaalenii_PYR-1 PAAPP---APPTPAAAPPSPAP----AAPAAATPAEPAAPS-ARPGPTPG Mflv_4416|M.gilvum_PYR-GCK T---------------------------------------------TTES MUL_0637|M.ulcerans_Agy99 ----------------------------------------------AEDL TH_3373|M.thermoresistible__bu R---------------------------------------------ARNA . MMAR_2823|M.marinum_M T---------------------------TPTTTVPSS--PSSSPATE--- MAV_2780|M.avium_104 T---------------------------TPTTTPSTSVVPSTTPGG---- MAB_3220|M.abscessus_ATCC_1997 T---------------------------TTTTTTTTTITPAPSGAPE--- Mb0767|M.bovis_AF2122/97 P--------------------------GTGANGAPGGWLLGNGGAGGSAA Rv3514|M.tuberculosis_H37Rv PGQAGGPGGPAGLWGNGGPGGAGGSGGGTGGAGGAGGWLFGVGGAGGVGG MSMEG_5543|M.smegmatis_MC2_155 P---------------------------CSDIGTAG-----PGGATG--- MLBr_01556|M.leprae_Br4923 P--------------------------HPGHPGMPTGPHPGPAPKPGGRP Mvan_2314|M.vanbaalenii_PYR-1 P--------------------------RPG----PSAPKPG-APKPAART Mflv_4416|M.gilvum_PYR-GCK S-------------------------VTTTTTTAPSTPETTMAPETT--- MUL_0637|M.ulcerans_Agy99 R----------------------------RALDDSGVLDVAVLSESE--- TH_3373|M.thermoresistible__bu P--------------------------MRATITEQDAVAALQRGLPR--- MMAR_2823|M.marinum_M ----------------SSPAPGGPSGTGG--------------PEGGGGG MAV_2780|M.avium_104 ----------------GGTVPGGPTGGGG--------------PGGGGGS MAB_3220|M.abscessus_ATCC_1997 ----------------GTPAPG-PTGGGG--------------PDGGSGA Mb0767|M.bovis_AF2122/97 AG---------------SGLPGGAGGAAG-----------LFGTGGAGGA Rv3514|M.tuberculosis_H37Rv AGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAELLFGAGGAGGA MSMEG_5543|M.smegmatis_MC2_155 ------------------QIPGGPGGTAG--------------PGGASGA MLBr_01556|M.leprae_Br4923 PRVGNNPFSSAQSVARPIPRPPAP------------------RPSASPSS Mvan_2314|M.vanbaalenii_PYR-1 PRVGNNPFSSQQPVERPAPRPQGPGGPRPGPGAGGPRPGGGPRPGASPGS Mflv_4416|M.gilvum_PYR-GCK ----------------GAPAPGDPSQPGG------------------GGS MUL_0637|M.ulcerans_Agy99 ----------------AVTALLGPAHAGS------------------AVL TH_3373|M.thermoresistible__bu ------------------PRGGAPRPGRR-----------------FSLT MMAR_2823|M.marinum_M VPG-------GPTGSGGPGG--------GGGSIPG--------------- MAV_2780|M.avium_104 IPG-------GPTGGGGPGG--------GGGSIPG--------------- MAB_3220|M.abscessus_ATCC_1997 IPG-------GPTGGGGPEG--------GSGSIPG--------------- Mb0767|M.bovis_AF2122/97 GGS----STVGDGGAGGAGGSGGWLL--GTGGVGGVGGLG---------- Rv3514|M.tuberculosis_H37Rv GTDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAGGAGSDGGALG MSMEG_5543|M.smegmatis_MC2_155 IPG-------GPGGAAGPDG--------ATGSIPG--------------- MLBr_01556|M.leprae_Br4923 MSP----RPGGAVGGGGPRPPRTGVPRPGGG-RP---------------- Mvan_2314|M.vanbaalenii_PYR-1 MPP----RPQGARPGGGPRP--GGGPRPGGGPRPTPG------------- Mflv_4416|M.gilvum_PYR-GCK IPG-------GPTGSGGPEG--------GGGSIPG--------------- MUL_0637|M.ulcerans_Agy99 LVG-------EETASLSVLG---------GGDAPP--------------- TH_3373|M.thermoresistible__bu VVG-------SAAAAVICLG--------GFGALVA--------------- * MMAR_2823|M.marinum_M ---GPTGGGGPGGGGG------------------------------TIPG MAV_2780|M.avium_104 ---GPTGGGGPGGGGG------------------------------SIPG MAB_3220|M.abscessus_ATCC_1997 ---GPTGGGGPEGGGG------------------------------HIPG Mb0767|M.bovis_AF2122/97 --AGAGGAGGVGGAGG----LLGAGGHGGAGGLG-----------AVTGG Rv3514|M.tuberculosis_H37Rv GTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGGTGGAGGDGVLGG MSMEG_5543|M.smegmatis_MC2_155 ---GPAGTAGPDGATG-----------------------------VIPGG MLBr_01556|M.leprae_Br4923 ---GAPVGGRSDAGGG----------------------------NYRGGG Mvan_2314|M.vanbaalenii_PYR-1 ---GAGRPGGGGGGGG----------------------------NYRGGG Mflv_4416|M.gilvum_PYR-GCK ---GPTGSGGPDGGGG-----------------------------SIPGG MUL_0637|M.ulcerans_Agy99 ---TMLAAAPVEGDAT-----------------------------STFDT TH_3373|M.thermoresistible__bu ---GAGPGDPLYGLRT-----------------------------MLFGD . MMAR_2823|M.marinum_M VGGGGG------------------------------GPGGGGG------- MAV_2780|M.avium_104 VGGGGG------------------------------GPGGGGG------- MAB_3220|M.abscessus_ATCC_1997 VGGGHG------------------------------GPGGGGG------- Mb0767|M.bovis_AF2122/97 VGGAGGAGGL--LAGL------------------LAGPGGAGG------- Rv3514|M.tuberculosis_H37Rv VGGTGGKGGVGGVAGLGGAGGAAGQLFSASGAAGNAGVGGAGGQGGDGGA MSMEG_5543|M.smegmatis_MC2_155 PGGT-------------------------------AGPGGASG------- MLBr_01556|M.leprae_Br4923 VG-ALPGGGSG----------------------GFRGRPGGGG------- Mvan_2314|M.vanbaalenii_PYR-1 AGGGAPAAGGG----------------------GFRGRPGGG-------- Mflv_4416|M.gilvum_PYR-GCK PTITG-------------------------------GPGGGSG------- MUL_0637|M.ulcerans_Agy99 LMTHLD------------------------------DEGGAPG------- TH_3373|M.thermoresistible__bu VVRDDP------------------------------VVLAAQT------- .. MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 ------------TGGRGFLN-DGGVGGAGGN--AGLLFGAGGTGGSGGAG Rv3514|M.tuberculosis_H37Rv GGAGADADQPGATGGTGFAGGAGGAGGAGGSSGAGGTNGSGGAGGQGGAG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 ---------------LGGDG------GAGGAGGNAGV--------LFGNA Rv3514|M.tuberculosis_H37Rv GAGGAGADNPTGIGGTGGDGGTGGAAGAGGAGGAAGTGGTGGMIGTTGNA MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 GSGGTGGFG----------DTD-----------GGAGGAGGDAGWLGSGG Rv3514|M.tuberculosis_H37Rv GVGGAGGQGGDGGAGGAGADADQPGATGGTGFAGGAGGAGGAGGSSGAGG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 VGGAGGFGETG-DGGVGGAG----------------GKAGLLIGNGGAG- Rv3514|M.tuberculosis_H37Rv TNGSGGAGGTGGQGGAGGAGGAGADNPTGIGGTGGDGGTGGAAGAGGAGG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M ---------CIGNI-CGSYP------------------------------ MAV_2780|M.avium_104 ---------CVGNV-CGAYP------------------------------ MAB_3220|M.abscessus_ATCC_1997 ---------CVDNVGCVSIP------------------------------ Mb0767|M.bovis_AF2122/97 -----GAGVLIGNGGNAGIGGTGPTAGDTGAG------------GISGLL Rv3514|M.tuberculosis_H37Rv AAGTGGTGGMIGTTGNAGVGGAGGQGGDGGAGGAGADADQPGATGGTGFA MSMEG_5543|M.smegmatis_MC2_155 ---------CIPNVGCATIPAP---------------------------- MLBr_01556|M.leprae_Br4923 -----HGGGGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPV Mvan_2314|M.vanbaalenii_PYR-1 ------GGGGRPGQRGGAAGAFGRPGGAPKRGRKSKRAKRAEYENMQAPV Mflv_4416|M.gilvum_PYR-GCK ---------SIPGGPTINIPVP---------------------------- MUL_0637|M.ulcerans_Agy99 ------EVLLVGSSEHTTVIADQFRDASTMRVEVPEDPTFALARGAAMAA TH_3373|M.thermoresistible__bu ---------QLAEVEQLIAQGDWEAAQERLQAVTTTVATVGDETRKQELV MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 LGADGFNAP----------ASASPLHTLKQQALAAIN-APTQTLTGRPLI Rv3514|M.tuberculosis_H37Rv GGAGGAGKAGGSSSAGGTNSSGSAGGTGRQSGTGGAGGAGADNPTGIGGT MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 VG--GVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVT Mvan_2314|M.vanbaalenii_PYR-1 VG--GVRLPHGNGETIRLARGASLSDFAEKINANPASLVQALFNLGEMVT Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 AGAGSTMAQQVLGGDAGEATTYLPPELAATASGQDEDEQLAYSQAGENEL TH_3373|M.thermoresistible__bu AEWQELSVKVESRNPDATVPPDAPPVTLPVIDPATSTEPTEPGTPSTEPA MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 G--NGTPGAVGSG------ATGAPG------------------------- Rv3514|M.tuberculosis_H37Rv GGDGGTGGAAGAGGAGGAAGTGGTGGMIGTTGNAGVGGAGGSSGAGGTNG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDE Mvan_2314|M.vanbaalenii_PYR-1 ATQSVGDETLELLGGEMNYVVQVVSPEDEDRELLESFDLTYGEDEGGEED Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 LPVTGADEYGDYGPDDDEFADDYEDEAP---------------------- TH_3373|M.thermoresistible__bu EPGEPTEP------------------------------------------ MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 ----GWLLGDGGAGGSGAAGSGAP------------------GGAGGAAG Rv3514|M.tuberculosis_H37Rv SGGAGGTDGQGGAGGAGGAGADNPTGIGGTGGDGGTGGAAGAGGAGGAAG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 LQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVGVD Mvan_2314|M.vanbaalenii_PYR-1 LEIRPPVVTVMGHVDHGKTRLLDTIRNATVREGEAGGITQHIGAYQVTVD Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 ---AGTRLSSRSLLISNAVVAFAVIGFASLAVAVAVAIRPTAASEPVEGH TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 LWGTG---------GAGGAGG------------------------WLLGD Rv3514|M.tuberculosis_H37Rv TGGTGGMIGTTGNAGVGGAGGQGGDGGAGGAGADADQPGATGGTGFAGGA MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 LDGSERLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEA Mvan_2314|M.vanbaalenii_PYR-1 LDGTERPITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEA Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 QNAQPGKFMPLLPTQQQAPVPPPPPDAPTAGFQGGTIPTVQGVVPRQATP TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 GGAGGIGGASTVLG-----------------------------GTGGGGG Rv3514|M.tuberculosis_H37Rv GGAGGSGGSSCAGGTNGSGGAGGTCGQVVAGGAGISFSNGSNGGTGGTGG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 INHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFID Mvan_2314|M.vanbaalenii_PYR-1 INHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVPEEYGGDAMFVD Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 TVPGPVAPAP----------------------------------AAAPGV TH_3373|M.thermoresistible__bu ------------------------------------------------GD MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 VGGLWGAGG-----AG--GAGGTGLVGGDGGAGGAGGTGGL-LAGLIGAG Rv3514|M.tuberculosis_H37Rv VGGTGGDGGNAGTGAGDPGKGGTGGTGGTGGSGGAGGSGGANFNGGTGGT MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ISAKVGTNIEALLEAVLLTADAALDLRANSGMEAQGVAIEAHLDRGRGPV Mvan_2314|M.vanbaalenii_PYR-1 ISAKQGTNIEALLEAVILTADASLDLRANPDMEAQGVAIEAHLDRGRGPV Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 VPAPIPLPIPIIIPPWPNWSPGMPTPSTVTVTPTTPTTTAPSTLTPTTPT TH_3373|M.thermoresistible__bu PDMPVDGTEPTSPGTEPTAGPDQPTVPPTVGPTSEPATSEPAMTAPTTTV MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 GGHGGTGGLNTN------------------------------GDGGVGGA Rv3514|M.tuberculosis_H37Rv GGTGGKGGLNTDGLSSATSGTGGTGGTGGKGGTGGAGDDSAGGTGGTGGA MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ATVLVQRG-----------------------------TLRIGDSVVAGDA Mvan_2314|M.vanbaalenii_PYR-1 ATVLIQRG-----------------------------TLRVGDSVVAGDA Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 TTAP---------------------------------------------- TH_3373|M.thermoresistible__bu PTSAPG-------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 GGNAGM-------------------------------------------- Rv3514|M.tuberculosis_H37Rv GGNAGAGGLANTGGTAGNAGIGGDGGQGGNGGQGDSGSGLGGQPGFAGGA MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 YG------------------------------------------------ Mvan_2314|M.vanbaalenii_PYR-1 YG------------------------------------------------ Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 --------------------------------------------LAGPGG Rv3514|M.tuberculosis_H37Rv GGKGGAGGSSGAGGTNGSGGAGGAGGQGGAGGAGISFSNGSNGGTGGTGG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ------------------------RVRRMVDEHGVDIEAALPSSPVQVIG Mvan_2314|M.vanbaalenii_PYR-1 ------------------------RVRRMVDEHGEDVEEALPSRPVQVIG Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -----------------------------------STLTPSTPTTTAPST TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 AGGAGGDGENLDT----------------GGDGGAGGSAGLLF------- Rv3514|M.tuberculosis_H37Rv VGGTGGDGGNAGTGAGDPGKGGTGGTGGTGGSGGAGGSGGANFNGGTGGT MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 FTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDS Mvan_2314|M.vanbaalenii_PYR-1 FTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARTRKRISLEDLDS Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 LTPTTPTTTVPSTVITPTTTAPITPITVAPTTVNPTTVAPTTVAPTTQQT TH_3373|M.thermoresistible__bu --------------------------SAVRTTTSAPTTATTTSGSTTAGP MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 -GSGGAGGAGGFGFLGGDGGAGGNAG--------LLLSSGGAGGFGGFGT Rv3514|M.tuberculosis_H37Rv GGTGGTGGKGGMGGIAGDGGPGGDGGNAGVGGKGGTNGNGGSGGTGGTGG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITE Mvan_2314|M.vanbaalenii_PYR-1 ALKETSQLNLILKGDNSGTVEALEEALLGIQVDDEVELRVIDRGVGGVTE Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 VVPQPTQETVAPPPTQQTVAPQPTIAPQPTQQALEPPSGGSSGGSSGGGS TH_3373|M.thermoresistible__bu TAGGPTSSGPATGPTSVPREPGAGAGTTEPTAPAARAGEDGVGGDGTVGG MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 AGGVGGAG------GNAGWLGFGGAGGIGGIGGNAN-------------- Rv3514|M.tuberculosis_H37Rv AGGNAGAGGLANTGGTAGNAGIGGDGGQGGNGGQGDSGSGLGGQPGFAGG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 TNVNLASASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEK Mvan_2314|M.vanbaalenii_PYR-1 TNVNLASASDAIIIGFNVRAEGKATELANREGVEIRYYSIIYQAIDEIES Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 SSGGGSSSGGGSSSGRGSSSGGSSSGGHSSGGGS---------------- TH_3373|M.thermoresistible__bu DGAFAEETVGEVPQLTATTTVVLPQSGAADAAGD---------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 ----GGAGGNGGTG------------------------------------ Rv3514|M.tuberculosis_H37Rv PGGKGGAGGNAGTGGTNGSGAGGAGGQGGAGGAGISFSNGSNGGTGGTGG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ALRGMLKPIYEEN------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 ALKGMLKPVYEEK------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 --------------------------GQLWGSGGAGGEGGAALS--VGDT Rv3514|M.tuberculosis_H37Rv VGGTGGDGGNAGTGAGDPGKGGTGGTGGTGGSGGAGGSGGANFNGGTGGT MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ---------------------------QLGRAEIRALFRSSKVGIIAGCI Mvan_2314|M.vanbaalenii_PYR-1 ---------------------------ELGRAEIRAIFRSSKVGNIAGCL Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 GGAGGVGGSAGL-------------------------------------- Rv3514|M.tuberculosis_H37Rv GGTGGTGGKGGMGGIAGDGGPGGDGGNAGVGGKGGTNGNGGSGGTGGTGG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ISSGVVRRNAKVR------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 VQSGIMRRNAKAR------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0767|M.bovis_AF2122/97 ----------------------------------IGTGGNGGNGGTGAN- Rv3514|M.tuberculosis_H37Rv PGGSGGAPTGSGTGGKGGAGGDGGDGADGGAATGVGDGGDGGNGGNGGNG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ------------------------------LLRDNIVVTDNLTVTSLRRE Mvan_2314|M.vanbaalenii_PYR-1 ------------------------------LLRDNVVVAENLTISSLKRE Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- TH_3373|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M ------------------------------------------- MAV_2780|M.avium_104 ------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 ------------------------------------------- Mb0767|M.bovis_AF2122/97 ---AGSPG-------TG-----GAGGLLLGQNGLNGLP----- Rv3514|M.tuberculosis_H37Rv GTGVGSPGGLGGAGGTGGLGGAGAGGGADGDDGDDGQPGNNGS MSMEG_5543|M.smegmatis_MC2_155 ------------------------------------------- MLBr_01556|M.leprae_Br4923 KDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA---- Mvan_2314|M.vanbaalenii_PYR-1 KDDVTEVRDGYECGLTLTYSDIKEGDVIETYELVEKART---- Mflv_4416|M.gilvum_PYR-GCK ------------------------------------------- MUL_0637|M.ulcerans_Agy99 ------------------------------------------- TH_3373|M.thermoresistible__bu -------------------------------------------