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M. bovis AF2122 / 97 Mb1485c (PE_PGRS27)

annotation: PE-PGRS family protein
coordinates: 1626985 - 1631211
length: 1408
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Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1485cPE_PGRS27-100% (1408)PE-PGRS family protein
M. bovis AF2122 / 97Mb3541PE_PGRS550.049.32% (1693) PE-PGRS family protein
M. bovis AF2122 / 97Mb0593cPE_PGRS70.051.40% (1430) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5091-1e-17846.01% (828) triple helix repeat-containing collagen
M. tuberculosis H37RvRv1450cPE_PGRS270.087.10% (1248) PE-PGRS family protein
M. leprae Br4923MLBr_01556infB2e-1133.95% (162) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_4284c-6e-5131.49% (543) hypothetical protein MAB_4284c
M. marinum MMMAR_3763-0.056.10% (1542) PE-PGRS family protein
M. avium 104MAV_4827-5e-2543.02% (172) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-17841.67% (1099) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-6e-4738.91% (329) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.047.59% (1162) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-17345.10% (827) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb1485c|M.bovis_AF2122/97           ------------MSLVIVAPETVAAAALDVARIGSSIGVANSAAAGSTTS
Rv1450c|M.tuberculosis_H37Rv        ------------MSLVIVAPETVAAAALDVARIGSSIGAANAAAAGSTTS
MMAR_3763|M.marinum_M               ------------MSFVSVAPEAVATAASDLARIGSSIDAVNAAAAGATTT
MUL_4367|M.ulcerans_Agy99           ------------MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------MSIIDFILNLFRDPVEAASYVADPEAALANAG--
MAV_4827|M.avium_104                -------------------MNIVLGVSMAPSSIQMVVLEGEYADG-----
MLBr_01556|M.leprae_Br4923          ------------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASS-
                                                                                      

Mb1485c|M.bovis_AF2122/97           VLA----------AGADEVSAAIATLFG----SHAREYQAIST--QVAAF
Rv1450c|M.tuberculosis_H37Rv        VLA----------AGADEVSAAIATLFG----SHAREYQAIST--QVAAF
MMAR_3763|M.marinum_M               VLA----------AGADEVSVAIAALFG----THAQEYQAIST--RISAL
MUL_4367|M.ulcerans_Agy99           VLP----------AAGDEVSAAIAELFG----GFGREYQAMGA--RVALL
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------MMFL----APPGGPGPISA--AIQLT
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------LSAVSAAQVGAVMPVVAESVASNYGYQSQWVN
MAV_4827|M.avium_104                ---------------------------------ATVEEDAIDVTGADDAA
MLBr_01556|M.leprae_Br4923          ------------------------------TVEAPVARRLRESFGGIKPA
                                                                                      

Mb1485c|M.bovis_AF2122/97           HDRFAQTLSAAVGSYVSAEATNAAPLATLEHNVLNALNAPTQ--------
Rv1450c|M.tuberculosis_H37Rv        HDRFAQTLSAAVGSYVSAEATNAAPLATLEHNVLNALNAPTQ--------
MMAR_3763|M.marinum_M               NERFVALLTAGNNSYAASESASVSWLQAVEQDVLGLVNAPSQ--------
MUL_4367|M.ulcerans_Agy99           HDDFVRALTAGGSAYGQAEALNMWPLQELEQQALGVVNAPSM--------
Mflv_5091|M.gilvum_PYR-GCK          -----------MVTFGGGATPTPTSLGAAAVDLSGTSCG-----------
Mvan_1264|M.vanbaalenii_PYR-1       STGSEATEPWYVVSFGGSGAPTPNNLAASLVDLSGTSCG-----------
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPR----------------
MAV_4827|M.avium_104                TASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALR-------
MLBr_01556|M.leprae_Br4923          ADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP-------
                                                                                      

Mb1485c|M.bovis_AF2122/97           --------------------------------------------------
Rv1450c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3763|M.marinum_M               --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           ----------------------------------ALLGRPLIGDGAAGAP
Rv1450c|M.tuberculosis_H37Rv        ----------------------------------ALLGRPLIGDGAAGAP
MMAR_3763|M.marinum_M               ----------------------------------NWFGRPLIGNGADGVA
MUL_4367|M.ulcerans_Agy99           ----------------------------------ALFGRPSIGNGVDGVA
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------LICNGQD---
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------LICNGQD---
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGING-T
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------DNDFLSHNDTDFA
MAV_4827|M.avium_104                --------------------------------------DALAARRIDNVM
MLBr_01556|M.leprae_Br4923          ------------------------------------VQVDHSAAVVPIVA
                                                                                      

Mb1485c|M.bovis_AF2122/97           GTGQAGGAGGILWGNGGAGG-SGAPGQVGGAGGAAGLFGTGGAGGAG---
Rv1450c|M.tuberculosis_H37Rv        GTGQAGGAGGILWGNGGAGG-SGAPGQVGGAGGAAGLFGTGGAGGAG---
MMAR_3763|M.marinum_M               GTGQAGGAGGILWGNGGAGG-SGAVGQSGGAGGSAGLLGHGGAGGAGGQA
MUL_4367|M.ulcerans_Agy99           GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAG---
Mflv_5091|M.gilvum_PYR-GCK          GTGQN---GGILFGNGGSGWNSDVVGMDGGNGGNGGLFG--GNGGNG---
Mvan_1264|M.vanbaalenii_PYR-1       GTGQN---GGILFGNGGSGWNSEIAGVSGGNGGNAGLFG--GNGGNG---
MSMEG_0868|M.smegmatis_MC2_155      ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVG---
TH_3810|M.thermoresistible__bu      ------------------------VDGDGGSGGRTGLFSKLSRGGDG---
MAB_4284c|M.abscessus_ATCC_199      SHNPIASGNQVMSPSGNVDSFNRGPLLDLSFG--DLQFGNRDTTAIG---
MAV_4827|M.avium_104                LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP---
MLBr_01556|M.leprae_Br4923          GEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTG---
                                                                   .                  

Mb1485c|M.bovis_AF2122/97           ---GAGAAGGAGGSGGWLLGNGGVG-------------------------
Rv1450c|M.tuberculosis_H37Rv        ---GAGAAGGAGGSGGWLLGNGGVG-------------------------
MMAR_3763|M.marinum_M               GASGTGGVGGAGGAGGWLYGNGGTGGVGGEGPVNGGVGGAGGRAWLLGAG
MUL_4367|M.ulcerans_Agy99           ---GVGAAGMTGGSG-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ---GNGLGGGNGGNG-----------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---GNGLGSGDGGNG-----------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ---WAGLDGGNGGSG-----------------------------------
TH_3810|M.thermoresistible__bu      ---GDGGLGGNGGHG-----------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----DGAVAVGGSNS-----------------------------------
MAV_4827|M.avium_104                --DVYKQQIRAESYG-----------------------------------
MLBr_01556|M.leprae_Br4923          --PHPGPAPKPGGRP-----------------------------------
                                                .                                     

Mb1485c|M.bovis_AF2122/97           ---GAGGQSL-LGGATGGAGGNAGLFGVGGTG------------GPGGPG
Rv1450c|M.tuberculosis_H37Rv        ---GAGGQSL-LGGATGGAGGNAGLFGVGGTG------------GPGGPG
MMAR_3763|M.marinum_M               GSGGAGGQGLGLNGGAGGAGGNGGLFGIGGTGGAGGDSAGSGSAGAGGDG
MUL_4367|M.ulcerans_Agy99           ----------------GAGGGGGWLWGAGGSG------------------
Mflv_5091|M.gilvum_PYR-GCK          -----------------GNAGAFALFGNGGNG------------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------------GDAGLFSLFGRGGNG------------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------------GLLMGIGGAG------------------
TH_3810|M.thermoresistible__bu      ----------------------------GGTG------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------GPIASG---------------------
MAV_4827|M.avium_104                -------------------------DAAGQLS------------------
MLBr_01556|M.leprae_Br4923          -------------------------PRVGNNP------------------
                                                                *                     

Mb1485c|M.bovis_AF2122/97           GPGGPGGPGGPGGVG---------GTGGAGGLGGTLYGAGGHGGAGGPGP
Rv1450c|M.tuberculosis_H37Rv        G---------PGGVG---------GTGGAGGLGGTLYGAGGHGGAGGPGP
MMAR_3763|M.marinum_M               GHGGLWGRGGAGGIGGVNSDSGDGGAGGGGGAGGRLFGSGGAGGAGGTGA
MUL_4367|M.ulcerans_Agy99           --------GAAG-------------AGGSGGSGGWLWGNAGQTAGAG---
Mflv_5091|M.gilvum_PYR-GCK          ---------------------------GNGGVG-----------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------------GNGGVG-----------------
MSMEG_0868|M.smegmatis_MC2_155      ------------------------GAGGVGADGTSAHVDGGTGGTGGTG-
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           IGGVGGHGGVGGAAG-LLGVGGHGGAGGHGAAGIAGAAGKGGIFPDGSNG
Rv1450c|M.tuberculosis_H37Rv        IGGVGGHGGVGGAAG-LLGVGGHGGAGGHGAEGVAGAAG-EDLSPHGTSG
MMAR_3763|M.marinum_M               VAGSGGDGGAGGAAVGLWGLGGHGGAGGDGAVGLAGGVG--------EAG
MUL_4367|M.ulcerans_Agy99           VGGAGGAGGAGDAGD--QGVSG-VAPGEAGAVGFAGGAG-----------
Mflv_5091|M.gilvum_PYR-GCK          VVGATGAVGAPGVAG------------ATGATGVTSGVV-----------
Mvan_1264|M.vanbaalenii_PYR-1       IAGATGAVGAPGVAG------------ATGATGVTSNVT-----------
MSMEG_0868|M.smegmatis_MC2_155      -GGTGGTGGIGGTGG-----GLFGLLGHSGSTGAAGAAG-----------
TH_3810|M.thermoresistible__bu      ------------------------------IISLLSLAG-----------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------QGSTAVNGDVR-----------
MAV_4827|M.avium_104                -------------------------AMVAGLEKLESLPG-----------
MLBr_01556|M.leprae_Br4923          ---------------------------FSSAQSVARPIP-----------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GAGGDAGDGGTGGRGGWLAGAGGAGGDGGIGGTGGAGGAGFSRALIVAGD
Rv1450c|M.tuberculosis_H37Rv        GVGGDAGDGGTGGRGGWLAGAGGAGGAGGVGGTGGAGGAGFSRALIVAGD
MMAR_3763|M.marinum_M               GEGGSAGNGGAGGLGGWLIGSGGAGGLGGVGGAGGAGGAG--AAGIAPGS
MUL_4367|M.ulcerans_Agy99           GAGGAGGNGVGGG----VNGAGGAGGAGGVGGGGGAGASG-----VGAGV
Mflv_5091|M.gilvum_PYR-GCK          --GGNGED---------AVGYGATGAAGAAGAAGAAGAAG----------
Mvan_1264|M.vanbaalenii_PYR-1       --GGNGAD---------AVGYGATGAAGAAGAAGAAGKAG----------
MSMEG_0868|M.smegmatis_MC2_155      -NGGDGGNGGFG--YVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPG-
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------DSNIINADHGSNVGVDQSQ----------
MAV_4827|M.avium_104                -------------------------GLLLVGSGVDVAP------------
MLBr_01556|M.leprae_Br4923          --------------RPPAPRPSASPSSMSPRPGGAVGGGG----------
                                                                                      

Mb1485c|M.bovis_AF2122/97           NGGDGGNGGMGGAGGAGGPGGAGGLISLLGGQGAGGDGGDGGAGGVGGDR
Rv1450c|M.tuberculosis_H37Rv        NGGD----------------------------------------------
MMAR_3763|M.marinum_M               NGGNGGNGGVGGAGGVGGSGGQGGFLRFLGGQGDGGAGGAGGAGGVAGDG
MUL_4367|M.ulcerans_Agy99           AGGDGGTG------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GAGANGNQAVNAGAGGAGGHGGDPGAGGAGGTGGAGSTIGAHGAAGASPT
Rv1450c|M.tuberculosis_H37Rv        -----------------------PGAGGAGGTGGAGSTIGAHGAAGASPT
MMAR_3763|M.marinum_M               GKGADAAAFSG-AAGGNGGHGGDNGAGGAGGTGGAGSTVGAHGADGFSPI
MUL_4367|M.ulcerans_Agy99           ------------------------GAGGAAGVGGAAGTGGTGGAAGVAGT
Mflv_5091|M.gilvum_PYR-GCK          -------------------------AVGSAGAAGEAGETGTWGNAGLPGK
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------AVGSAGTAGSAGAPGVWGNAGLPGA
MSMEG_0868|M.smegmatis_MC2_155      ------------------------KGGGGGGGGGGAILIGANGGTVDGHA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------TRVGGDYTNVSGHGSADIDKS
MAV_4827|M.avium_104                ----------------------------LKQVLQTTTFLDVSVAEEPETA
MLBr_01556|M.leprae_Br4923          ---------------------------PRPPRTGVPRPGGGRPGAPVGGR
                                                                                      

Mb1485c|M.bovis_AF2122/97           SGGNGGAGGNGAH--FSSGGKAGGNG-----GAGGAGGLVGNGGAGGAGG
Rv1450c|M.tuberculosis_H37Rv        SGGNGGAGGNGAH--FSSGGKAGGNG-----GAGGAGGLVGNGGAGGAGG
MMAR_3763|M.marinum_M               TGGNGGDGGNGASGPAASAGVAGGAG-----GAGGDGGLYGNGGAGGDGG
MUL_4367|M.ulcerans_Agy99           GGDGGDGGAGGAGSDASLAGQAGFAG-----GSGGAGGVGGSAGAGGVNG
Mflv_5091|M.gilvum_PYR-GCK          AGDAGGAGAVGAAGAAGTVGTAGATG-----GTG----------------
Mvan_1264|M.vanbaalenii_PYR-1       AGAAGGAGAIGTAGVAGAAGTAGATG-----GTG----------------
MSMEG_0868|M.smegmatis_MC2_155      IGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHST
TH_3810|M.thermoresistible__bu      ---NGGNGGNGYRTTDNNALDGGHGG------------------------
MAB_4284c|M.abscessus_ATCC_199      VTVVDDHSQRNTTNINDSFNTDRSTN------------------------
MAV_4827|M.avium_104                LARGAALAAANAPLFASSTAALAYAQ------------------------
MLBr_01556|M.leprae_Br4923          SDAGGGNYRGGGVGALPGGGSGGFRG------------------------
                                              .                                       

Mb1485c|M.bovis_AF2122/97           NGAPG-----APPSGGD-PNGGGGGAGGAGGKGGDGGAQAGD-GGAGGAG
Rv1450c|M.tuberculosis_H37Rv        NGAPG-----APPSGGD-PNGGGGGAGGAGGKGGDGGAQAGD-GGAGGAG
MMAR_3763|M.marinum_M               NGVAGGQGADATAAGASGENGGDGGAGGMGGAGGMGGVLGGH-GGAGGIG
MUL_4367|M.ulcerans_Agy99           S-------------------GGDGGAGAAGGAGGASATVAGS-GGVGGDG
Mflv_5091|M.gilvum_PYR-GCK          -------------------TGANGGAGGVGGVGGTG-AAGAA-GGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1       -------------------VGGNGGAGQAGGIGGTG-AAGAA-GQAGTAG
MSMEG_0868|M.smegmatis_MC2_155      GTG----------------IGGNGGIGSVYAYGNNGAVSGTATGGRGGDG
TH_3810|M.thermoresistible__bu      -------------------NGGNVGFFSLFNLGGAG--------GWGGSG
MAB_4284c|M.abscessus_ATCC_199      ---------------------IGSGNTTNTEIGSHNQANIGTSTSAGGSA
MAV_4827|M.avium_104                ----------------------DPGTGAVDQYSLPDYLYVPVDPEPGDDE
MLBr_01556|M.leprae_Br4923          --------------------RPGGGGHGGGGRPGQRGGAAGAFGRPGGAP
                                                          . *                     *   

Mb1485c|M.bovis_AF2122/97           GKGGNGGNGATGATGLNGLGAG-ADGTDGGKGGNGGAGGGGGAGGQGGKA
Rv1450c|M.tuberculosis_H37Rv        GKGGNGGNGATGATGLNGLGAG-ADGTDGGKGGNGGAGGGGGAGGQGGKA
MMAR_3763|M.marinum_M               GVGATGGSGGLGATGAEGVTGGNLHGGDGGNGGKGGIGGAGGDGGAGGKA
MUL_4367|M.ulcerans_Agy99           GAGGAAG-GGVGAASLG------------GDGGHAGAGGAGGEGLSGG--
Mflv_5091|M.gilvum_PYR-GCK          ETGTTGGAGGVG-----------------GQGTAGGTGGVGG--------
Mvan_1264|M.vanbaalenii_PYR-1       ETGVTGGVGGIG-----------------GQGTEGGTGGVGG--------
MSMEG_0868|M.smegmatis_MC2_155      IDGGTGGAGGMGEIYSG----------ADGEATGISAGGDGGSATGADSL
TH_3810|M.thermoresistible__bu      VDG---------------------------------VDVVGG--------
MAB_4284c|M.abscessus_ATCC_199      AVGGNAG-----------------------LAGNAGLAGNAG--------
MAV_4827|M.avium_104                LAYSAVG----------------------EEDAESPTVVIEKLFLP----
MLBr_01556|M.leprae_Br4923          RRGRKSKRQKRQ------------------EYDSMQAPVVGGVRLPHGNG
                                                                                      

Mb1485c|M.bovis_AF2122/97           LAATHQDGSMGAGGAGGNGGAGGMGGDGGNGAKGTFDNGGDGVGGNGGNG
Rv1450c|M.tuberculosis_H37Rv        LAATHQDGSMGAGGAGGNGGAGGMGGDGGNGAKGTFDNGGDGVGGNGGNG
MMAR_3763|M.marinum_M               QAAGFADGTEGVGGAGGEGGAGGVAGDGGKGADAAAFSG--AAGGNGGHG
MUL_4367|M.ulcerans_Agy99           ----FNTG--AAGGIGGAGGAGGTGGDSG------------GVGGVNGDG
Mflv_5091|M.gilvum_PYR-GCK          -----------IGGAGSTGAVGGVGGKGIQ-------------GGQGLQG
Mvan_1264|M.vanbaalenii_PYR-1       -----------VGGVGATGGAGGVGGKGIQ-------------GGQGLQG
MSMEG_0868|M.smegmatis_MC2_155      GGRGGTSWVQAGYGPTTGGKASGTAKAGHG-----------GKASDGGKG
TH_3810|M.thermoresistible__bu      ---------------NPDGGTPGAHGESHT---------------PGVYT
MAB_4284c|M.abscessus_ATCC_199      --------------LAGNAGLAGNAGLAGN----------------AGLA
MAV_4827|M.avium_104                --------------EDSEPRRRPVLLVGSG---------------LAVVG
MLBr_01556|M.leprae_Br4923          ETIRLARGASLSDFAEKIDANPAALVQALFNLG-----EMVTATQSVGDE
                                                               .                      

Mb1485c|M.bovis_AF2122/97           GSRGIGGAGGIGGAGSTAGADGARGATPTSGGNGGTGGNGAN--ATVAGG
Rv1450c|M.tuberculosis_H37Rv        GSRGIGGAGGIGGAGSTAGADGARGATPTSGGNGGTGGNGAN--ATVAGG
MMAR_3763|M.marinum_M               GDNGAGGAGGTGGAGSTVGAHGADGFSPITGGNGGDGGNGASGPAASAGV
MUL_4367|M.ulcerans_Agy99           GAGGGGGRGGDGGSSTSTSG---------VGGAGGAGGNGGN--------
Mflv_5091|M.gilvum_PYR-GCK          GKGGDGGAGGKGGDADSMGS---------AGATGGKGGNGGN--------
Mvan_1264|M.vanbaalenii_PYR-1       GQGGDGGTGGTGGDATSMGE---------AGATGGKGGNGGN--------
MSMEG_0868|M.smegmatis_MC2_155      GNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHG
TH_3810|M.thermoresistible__bu      DRQGEDGEDGTG------------------TGIGGRGGNGGS--------
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAGLAGNAGLAGN----------AGLAGNAGLAGN--------
MAV_4827|M.avium_104                ISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAPP--------
MLBr_01556|M.leprae_Br4923          TLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDE--------
                                                                         .            

Mb1485c|M.bovis_AF2122/97           AGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGSSPTTAGESGTSGQNGGA
Rv1450c|M.tuberculosis_H37Rv        AGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGSSPTTAGESGTSGQNGGA
MMAR_3763|M.marinum_M               AGGAGGAGGDGGLYGNGGAGGDGGNGVAGGQGADATAAGASGENGGDGGA
MUL_4367|M.ulcerans_Agy99           AGFGVSAGGTGGSAGDGGAGG-GAGGVDGVGGAS-----------GNGGA
Mflv_5091|M.gilvum_PYR-GCK          -------GGRGGLFGKGGNAGNGADGGTG----------------GAGGA
Mvan_1264|M.vanbaalenii_PYR-1       -------GGRGSLFGRGGNAGNGGNGGTG----------------GNGGN
MSMEG_0868|M.smegmatis_MC2_155      SITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGN
TH_3810|M.thermoresistible__bu      -------SSGTHPMAEDGEHVKALDGRPG----------------LDGGN
MAB_4284c|M.abscessus_ATCC_199      -------AGLAGNAGLAGNAGLAGNAGLAG----------------NAGL
MAV_4827|M.avium_104                --------PVQASAPQPKISVPEPVAAPKP---------------LSPPV
MLBr_01556|M.leprae_Br4923          ------LQVRPPVVTVMGHVDHGKTRLLDTIRKAN---------VREAEA
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGAGGAGGRGGDFGGDGGTGGAGGNGADGGAGGNGANGANATTPG-AKGG
Rv1450c|M.tuberculosis_H37Rv        GGAGGAGGRGGDFGGDGGTG---------GAGGNGANGANATTPG-AKGG
MMAR_3763|M.marinum_M               GGMGGAGGMGGVLGGHGGAGGIGGVGATGGSGGLGATGAEGVTGGNLHGG
MUL_4367|M.ulcerans_Agy99           AGAGGAGGSGIGAGIDGGAG---------GAGGTG--GAAGFPGG---GG
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGG-------AGGTG---------GTGGTGGIGGAGSTGG--TGG
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGG-------NGGTG---------GTGGTGGIGGAGSTGG--TGG
MSMEG_0868|M.smegmatis_MC2_155      GGDGGFNGTGGATGGRGGDG---------AGASVWKANGQHSTGQTDTGG
TH_3810|M.thermoresistible__bu      GSHG---------------------------------------------G
MAB_4284c|M.abscessus_ATCC_199      AGNAGLAG---------------------------------------NAG
MAV_4827|M.avium_104                AAPLPAAP---------------------PPAAPPLPEAPPIPAAPPVVP
MLBr_01556|M.leprae_Br4923          GGITQHIGAYQVGVDLDGSER--------LITFIDTPGHEAFTAMRARGA
                                    ..                                                

Mb1485c|M.bovis_AF2122/97           DGGHGGPGA---QGGNGGQGGPGGLAGNLFGQNGIQGVGGSGGKGGAGGL
Rv1450c|M.tuberculosis_H37Rv        DGGHGGPGA---QGGNGGQGGPGGLAGNLFGQNGIQGVGGSGGKGGAGGL
MMAR_3763|M.marinum_M               DGGNGGKGG---IGGAGGDGGAGGKAQAAGFADGTEGAGGAGGEGGAGGV
MUL_4367|M.ulcerans_Agy99           TTGAWGTGG---AGGAGGAGGAGDHGGVGVNPGDSGTAGWAGGAGGAGGA
Mflv_5091|M.gilvum_PYR-GCK          TGGTGGTGG---TGGTGGTGGTG-------------GTGGTGGKGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGTGG---TGGTGGTGGTG-------------GTGGTGGKGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      NGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGAL
TH_3810|M.thermoresistible__bu      NGGHGGRGG-------------------------FLGIGGSGGWGG----
MAB_4284c|M.abscessus_ATCC_199      LAGNAGLAG-------------------------NAGLAGNAGLAGNAAV
MAV_4827|M.avium_104                VPVVVPPVP----------------------VPVPVRIPVPDPVSPPQLL
MLBr_01556|M.leprae_Br4923          KATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAK
                                                                                .     

Mb1485c|M.bovis_AF2122/97           AGDGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSGGAGSTPGAKGAHG
Rv1450c|M.tuberculosis_H37Rv        AGDGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSGGAGSTPGAKGAHG
MMAR_3763|M.marinum_M               AGDGGKGAD-AAAFSGAAGGNGGHGGDNGAGGAGGTGGAGSTVGAHGADG
MUL_4367|M.ulcerans_Agy99           GG--------SAAFNGVNG-AGGAGGNGGAGGGGGAGASGIGAGVAGGDG
Mflv_5091|M.gilvum_PYR-GCK          GG------------------AGGTGGDGGTGGTGGTGGTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       GG------------------DGGTGGTGGTGGTGGTGGTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      GG--------NGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGG
TH_3810|M.thermoresistible__bu      --------------------HGGNGGDTDADG------------------
MAB_4284c|M.abscessus_ATCC_199      AG------------------NAAVAGNAAVAGNAAVGGVLNTGVSGAIGG
MAV_4827|M.avium_104                AP-------------------PRLSVPQPVQPPVRVPQPPSPPQVGGTVP
MLBr_01556|M.leprae_Br4923          IRG---------QLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLL
                                                            .                         

Mb1485c|M.bovis_AF2122/97           FTPTSGGDGGDGGNGGH---------------------------------
Rv1450c|M.tuberculosis_H37Rv        FTPTSGGDGGDGGNGGN---------------------------------
MMAR_3763|M.marinum_M               FSPTTGGNGGDGGSGGSGFQGVKGGAGGVGGDGGLYGNGGTGGTGGTGGI
MUL_4367|M.ulcerans_Agy99           GTGGTGGAAGTGGAAGT---------------------------------
Mflv_5091|M.gilvum_PYR-GCK          AGDGTGGTGGTGGTGGQ---------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       AGDGLGGTGGTGGTGGF---------------------------------
MSMEG_0868|M.smegmatis_MC2_155      NGGAGRIRVNNGTATGT---------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SSHVGGAINESLGGSGS---------------------------------
MAV_4827|M.avium_104                QSPPQHQTPPGEGTPPK---------------------------------
MLBr_01556|M.leprae_Br4923          TADAALDLRANSGMEAQG--------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           ----SQVVGG----------------------------------------
Rv1450c|M.tuberculosis_H37Rv        ----SQVVGG----------------------------------------
MMAR_3763|M.marinum_M               GFNGSTTIGGGNGGDGHTGLTGGDGGAGGKGGALAGHGGDGGTGGVGGTG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           -----------------NGGDGGNGGNGGSAGT-GGNGGRG---------
Rv1450c|M.tuberculosis_H37Rv        -----------------NGGDGGNGGNGGSAGT-GGNGGRG---------
MMAR_3763|M.marinum_M               GTGGSGGTGTSGIFSSANGGDGGNGGDGGTGGT-GGVGGLGGQAQAAGFA
MUL_4367|M.ulcerans_Agy99           ------------------GGTGGAAGAAGSAGD-GGAGGAG---------
Mflv_5091|M.gilvum_PYR-GCK          ------------------GGQGGQGGTGGTGGQ-GGLGGGG---------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------GGQGGQGGTGGTGGQ-GGLGGVG---------
MSMEG_0868|M.smegmatis_MC2_155      ----------------ATGGNGGNGGNGDADGHRGGKGGDG---------
TH_3810|M.thermoresistible__bu      -------------------GNGGDGGNGGSAGR-GGTGGLR---------
MAB_4284c|M.abscessus_ATCC_199      -----------------VGGSTAVGGGAHTGVGGGVSTGVG---------
MAV_4827|M.avium_104                -----------------PDGPGNYGGGHVPTPGAGGSGGSG---------
MLBr_01556|M.leprae_Br4923          --------------VAIEAHLDRGRGPVATVLVQRGTLRIG---------
                                                             *   .                    

Mb1485c|M.bovis_AF2122/97           -------GDGAFGGMSANATNPGE--------------------------
Rv1450c|M.tuberculosis_H37Rv        -------GDGAFGGMSANATNPGE--------------------------
MMAR_3763|M.marinum_M               DGTQGVGGAGGVGGTGGNAGNGGHGANADVGSGKAGGNGGDGGDPGVGGI
MUL_4367|M.ulcerans_Agy99           -------GAGDDGSAGVVSGDPGT--------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           ------------------------------NGPNGNPGGNGGAGGAGGAG
Rv1450c|M.tuberculosis_H37Rv        ------------------------------NGPNGNPGGNGGAGGAGGAG
MMAR_3763|M.marinum_M               GGQGGAGSIAGVEGAAGVAPTSGGNGGDGGNGASGATGVNGGAGGSGGDG
MUL_4367|M.ulcerans_Agy99           ---------------------------------AGKAGGAGGAGGVGGNG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------GTGGQGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------------GEALIRATVIGSNASG
TH_3810|M.thermoresistible__bu      -----------------------------------------GVFGINGGN
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------------VGSHVGGG
MAV_4827|M.avium_104                ----------------------------------------GGHVPTPGAG
MLBr_01556|M.leprae_Br4923          ----------------------------------------DSVVAGDAYG
                                                                                   . .

Mb1485c|M.bovis_AF2122/97           ---LNGGNGGAGGNGGLG-------------------GFGGNGAAGANGV
Rv1450c|M.tuberculosis_H37Rv        ---LNGGNGGAGGNGGLG-------------------GFGGNGAAGANGV
MMAR_3763|M.marinum_M               GLYGNGGDGGDGGNGGKGQVGSTGPVAGSAGGTGGTGGTGGQGGAGGSGG
MUL_4367|M.ulcerans_Agy99           ---VAGGVNGSGGAGGAG-------------------GAGGTGGAGASGV
Mflv_5091|M.gilvum_PYR-GCK          ------GQGGTGGTGGTG-------------------GTGGTGGAGG---
Mvan_1264|M.vanbaalenii_PYR-1       ------GQGGTGGTGGTG-------------------GTGGTGGAGG---
MSMEG_0868|M.smegmatis_MC2_155      --TATGGDGGNGGTLGATN------------------GTGGAATIVAYNV
TH_3810|M.thermoresistible__bu      ------GRAGLGGRGXXX--------------------------------
MAB_4284c|M.abscessus_ATCC_199      ISESLGGSGSVGGSTAVG--------------------------------
MAV_4827|M.avium_104                ------GSGGSGGGHVPT--------------------------------
MLBr_01556|M.leprae_Br4923          RVRRMVDEHGVDIEAALP--------------------------------
                                          .  . .                                      

Mb1485c|M.bovis_AF2122/97           AVGAPGQPG-GAGGHGGAGGNG----------------------------
Rv1450c|M.tuberculosis_H37Rv        AVGAPGQPG-GAGGHGGAGGNG----------------------------
MMAR_3763|M.marinum_M               ALAGHGGDG-GSGGDGGTGGTGGTGRNGANGITGADIDGGSGGKGGNGGT
MUL_4367|M.ulcerans_Agy99           PASVDGGDG-GAGGAGGAAGTG----------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----DGGLG-GLGGFGGSGGTG----------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----DGGLG-GLGGFGGVGGTG----------------------------
MSMEG_0868|M.smegmatis_MC2_155      VQANPQASGTATDGHGGSGING----------------------------
TH_3810|M.thermoresistible__bu      -------XG---GGVGAAVRSG----------------------------
MAB_4284c|M.abscessus_ATCC_199      --------GGAHTGVGGGVSTG----------------------------
MAV_4827|M.avium_104                ------------PGTGGPGGTG----------------------------
MLBr_01556|M.leprae_Br4923          ------SSPVQVIGFTSVPGAG----------------------------
                                                 *  .    *                            

Mb1485c|M.bovis_AF2122/97           -GAGGNGGQG------VVSDGAGGAGGAGGDGGAPGDGANGGNGQGAGAF
Rv1450c|M.tuberculosis_H37Rv        -GAGGNGGQG------VVSDGAGGAGGAGGDGGAPGDGANGGNGQGAGAF
MMAR_3763|M.marinum_M               GGAGGAGGQGGQAQAAGYSDGTQGVGGAGGDGGTAGIGGDGGDGANAVAG
MUL_4367|M.ulcerans_Agy99           -GSGGSAGNT----------GAGGAGGAGGAGGSAASTGVNGDG------
Mflv_5091|M.gilvum_PYR-GCK          -GQGGLGGPG------------GSTGGAGGAGGQAGTAGKGG--------
Mvan_1264|M.vanbaalenii_PYR-1       -GQGGQGGPG------------GSTGGAGGAGGQAGVAGKGG--------
MSMEG_0868|M.smegmatis_MC2_155      -GHGGNGGQG-----TIEANGPSAVASGIGAGGNGGDGIDGGLG------
TH_3810|M.thermoresistible__bu      ------------------------NGVFSGGGGTPSAG------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------VGVGSHVGGGISESLGGSGSVG------
MAV_4827|M.avium_104                -------------------------GSGGGHVPTPGAGTPGGSG------
MLBr_01556|M.leprae_Br4923          -DNFLVVDED---------RIARQIADRRSARKRNALAARSRKR------
                                                             .   .     .              

Mb1485c|M.bovis_AF2122/97           AGGGGGRGGDGGNAGNAGAGGPGGTGSTAGKAGPAGSILHDGGNGGHGGH
Rv1450c|M.tuberculosis_H37Rv        AGGGGGRGGDGGNAGNAGAGGPGGTGSTAGKAGPAGSILHDGGNGGHGGH
MMAR_3763|M.marinum_M               SGERGGDGGHGGDPGNAGAGGQAGAGPTSGGNGKAGSGVTTGGNGGDGGD
MUL_4367|M.ulcerans_Agy99           -----------------GAGGAGGVG------GLGGDSAATAGGGGAGGD
Mflv_5091|M.gilvum_PYR-GCK          -----------------LFGGSGSAG----KAGATGAAGASGGKGAQGAT
Mvan_1264|M.vanbaalenii_PYR-1       -----------------LFGGSGSAG----TAGVTGASGASGGKGAQGAT
MSMEG_0868|M.smegmatis_MC2_155      -----------------GNGGDGVVNTTANAANPGSATGTATGGDGGKAT
TH_3810|M.thermoresistible__bu      -------------------------------FGVPTTIQFPAGSCTSRAV
MAB_4284c|M.abscessus_ATCC_199      -----------------------------GSTAVGGGAHTGVGGGVNTGV
MAV_4827|M.avium_104                ----------------------------------GGHLPFPGAGSTPGGS
MLBr_01556|M.leprae_Br4923          --------------ISLEDLDSALKETSQLNLILKGDNAGTVEALEEALM
                                                                                      

Mb1485c|M.bovis_AF2122/97           G-----------AASGGNGGP----GGHGGNGGNGGTG------------
Rv1450c|M.tuberculosis_H37Rv        G-----------AASGGNGGP----GGHGGNGGNGGTG------------
MMAR_3763|M.marinum_M               GGSGAIGVKGGAGGAGGDGGL----YGNGGNGGDGGTGGKGTVGDSGATL
MUL_4367|M.ulcerans_Agy99           G---------------GKGGA----GGAGVNGVGGGDG------------
Mflv_5091|M.gilvum_PYR-GCK          G---------------AQGAT----GAQGATGATGAAG------------
Mvan_1264|M.vanbaalenii_PYR-1       G---------------AQGAT----GAQGATGATGASG------------
MSMEG_0868|M.smegmatis_MC2_155      G----------TASQGGNGGPSWVQSGYGSTLGGNATG------------
TH_3810|M.thermoresistible__bu      S-------------------------REGIMPSSRAAS------------
MAB_4284c|M.abscessus_ATCC_199      G--------------------------VGSHVGGGISES-----------
MAV_4827|M.avium_104                G------------------------GGHLPTPGAGTPG------------
MLBr_01556|M.leprae_Br4923          G------------------------IQVDDEVALRVIDR-----------
                                    .                                                 

Mb1485c|M.bovis_AF2122/97           -----------------------ANGGNGGIGGTGGAGSTGAKG------
Rv1450c|M.tuberculosis_H37Rv        -----------------------ANGGNGGIGGTGGAGSTGAKG------
MMAR_3763|M.marinum_M               SADGDRGGAGATGGVGGAGGDGGAKGGNGGLGGSGGTGGMGGTGGDGAHG
MUL_4367|M.ulcerans_Agy99           --------------------------GKGGTGGAGGAGGAGSDG------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------KAGATGAAGAAGAAGSAG------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------AQGSAGSAGSAGVAGSAG------
MSMEG_0868|M.smegmatis_MC2_155      ----------------------TATAGKGGEASNGGVAGNGGNA------
TH_3810|M.thermoresistible__bu      -------------------------------ARAGAACASSTSR------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------LGGSGSVGGSTAVG------
MAV_4827|M.avium_104                -------------------------------GGLGGFGGGHAPAP-----
MLBr_01556|M.leprae_Br4923          -----------------------------GVGGITETNVNLASAS-----
                                                                   .                  

Mb1485c|M.bovis_AF2122/97           -----VLGTNEGDGGDGGRGGNGGRGGNGGQG-----------LTGAGGN
Rv1450c|M.tuberculosis_H37Rv        -----VLGTNEGDGGDGGRGGNGGRGGNGGQG-----------LTGAGGN
MMAR_3763|M.marinum_M               ADMASGSGANGGYGGYGGFGGVGGAGGTGGVGGQAHAAGFTDGATGAGGD
MUL_4367|M.ulcerans_Agy99           -----IIPSNGGLGGNGGNGGNGGQAFGDGVG-------------GAGGI
Mflv_5091|M.gilvum_PYR-GCK          -----TTGAQGSAGTNGANGANGSQGAAGKAG------------------
Mvan_1264|M.vanbaalenii_PYR-1       -----TTGAQGSAGTNGANGANGSQGAAGKAG------------------
MSMEG_0868|M.smegmatis_MC2_155      --LVMAAGTTGVATGNTATGGDGGAATTAGATG------------GAGGF
TH_3810|M.thermoresistible__bu      --------SRRSFCCSRA--------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------GGAHTSAINDALGGSGSVGGSTAVG------------------
MAV_4827|M.avium_104                ---------------GGGLGGGGGHAPAPGGG------------------
MLBr_01556|M.leprae_Br4923          -------DAIIIGFNVRAEGKATELASREGVEIR----------------
                                                     .                                

Mb1485c|M.bovis_AF2122/97           GGTGGTPGN---GGNGGNGASGDLVTSP------GDGGGGGRGGDAGRGG
Rv1450c|M.tuberculosis_H37Rv        GGTGGTPGN---GGNGGNGASGDLVTSP------GDGGGGGRGGDAGRGG
MMAR_3763|M.marinum_M               GGQGGTGGLGAWGGNGGDGADGSISGPPQNGGKGGDGGGGGPGGLGGQGG
MUL_4367|M.ulcerans_Agy99           GGKG------------GNAAIGTIVING---------GVGGAGGSGGLGG
Mflv_5091|M.gilvum_PYR-GCK          -------------------ATGTT----------------GATGAAGEDG
Mvan_1264|M.vanbaalenii_PYR-1       -------------------ATGTT----------------GATGAAGDAG
MSMEG_0868|M.smegmatis_MC2_155      SNIAAIHG----------AITDSTAISG--------HGGAGNGGNGGKGA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------YYLVIYQAIDDI
                                                                                      

Mb1485c|M.bovis_AF2122/97           DAGLGGSSGPGGTPGDWG-TGGTGGTG------------GTGGQGANGG-
Rv1450c|M.tuberculosis_H37Rv        DAGLGGSSGPGGTPGDWG-TGGTGGTG------------GTGGQGANGG-
MMAR_3763|M.marinum_M               LSGDGSSTGAAGELGTFG-NGGSGGNGGIGGNATGFNAPGTGGAGGNGGN
MUL_4367|M.ulcerans_Agy99           ATEDG--------------VGGVGCAG------------GAGGNGGRGD-
Mflv_5091|M.gilvum_PYR-GCK          DAG----------------SGGSGING------------GAGGAGGAGG-
Mvan_1264|M.vanbaalenii_PYR-1       DPG----------------SEAVDING------------GAGGAGGAGG-
MSMEG_0868|M.smegmatis_MC2_155      DGWVQAYDPAGPVGSKIANSSAVAGNG------------GDGGVNGTGG-
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------------GGAHTSAIN--
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          EKALRGMLKPIYEENQLGRAEIRALFR-------------SSKVGIIAG-
                                                                                      

Mb1485c|M.bovis_AF2122/97           -------LTGGRGG-----TGGNGG-----------AGGTGGTGHNGSQ-
Rv1450c|M.tuberculosis_H37Rv        -------LTGGRGG-----TGGNGGNGNTGGT--GGAGGTGGTGHNGSQ-
MMAR_3763|M.marinum_M               GAFGGSGGTGGRGGSSSVGTGGAGGDGGDGGMGFGGIGGGGGTGGQGGSG
MUL_4367|M.ulcerans_Agy99           ----MLFTVGGSGG-----TGGDGGGGGSASG------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -------ASGGDGG-----NGGNTSVWKSGGQ------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           --------PGMGGNGGAGGFGGNGFAGVGGRGGMGGSGGTGGTG--DAGP
Rv1450c|M.tuberculosis_H37Rv        --------PGMGGNGGAGGFGGNGFAGVGGRGGMGGSGGTGGTG--DAGP
MMAR_3763|M.marinum_M               VDAQGIGGAGNGGVGGNGGDGGDGWDAPGGQGGKGGQGGNGGDGSPPVPP
MUL_4367|M.ulcerans_Agy99           --------SGTGGSGGTGGVGG-----IGGDGKLGGFGGDGGDG------
Mflv_5091|M.gilvum_PYR-GCK          ----------EGGEGGDGGKGG-----AGAEGGAGGGGGAGGSG------
Mvan_1264|M.vanbaalenii_PYR-1       ----------EGGEGGAGGAGG-----DGSEGGAGGSGGAGGSG------
MSMEG_0868|M.smegmatis_MC2_155      ------TADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTG------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------ESMNSSINASHSSSMNESFGSSMGSHGAAGTG---------
MAV_4827|M.avium_104                ---------------------------LGGFGGGHSGGGLGGLG------
MLBr_01556|M.leprae_Br4923          ----------CIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVT
                                                                                      

Mb1485c|M.bovis_AF2122/97           FGTGTGGTGGHGGQGGGGG----FSILLGLGGLGGLGSPGSIATGTAGGA
Rv1450c|M.tuberculosis_H37Rv        FGTGTGGTGGHGGQGGGGG----FSILLGLGGLGGLGSPGSIATGTAGGA
MMAR_3763|M.marinum_M               FGGSSGGTGGTGGTGGAGGDRFVDTELVGIGGAGHGGVTGGGPTGPALVD
MUL_4367|M.ulcerans_Agy99           ---GDGGFGVIGGQGGGGG----------FGGLGGTGAGG------APSD
Mflv_5091|M.gilvum_PYR-GCK          ----AGGAGGAGGSGGSGG---------------------------SGGS
Mvan_1264|M.vanbaalenii_PYR-1       ----TGGAGGAGGSGGSGG---------------------------SGGA
MSMEG_0868|M.smegmatis_MC2_155      --GTTAGGSGNGGNGGNGG---------------------------NGGA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------FEAQGHAQG---------------------------HASE
MAV_4827|M.avium_104                -----------GGHK-----------------------------------
MLBr_01556|M.leprae_Br4923          EVREGFECGMTLGYSDIKE----------------------------GDV
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGGGGFGGLGGGEFV
Rv1450c|M.tuberculosis_H37Rv        GGGGGFGGLGGGEFV
MMAR_3763|M.marinum_M               GGTGGAGGSGGTGAH
MUL_4367|M.ulcerans_Agy99           KGINGEPGNPG----
Mflv_5091|M.gilvum_PYR-GCK          GGSGGAAGDSDD---
Mvan_1264|M.vanbaalenii_PYR-1       GGSGGAAGDSD----
MSMEG_0868|M.smegmatis_MC2_155      DGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu      ---------------
MAB_4284c|M.abscessus_ATCC_199      TAHTTLPGAEHH---
MAV_4827|M.avium_104                ---------------
MLBr_01556|M.leprae_Br4923          IESYELVEKQRA---