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MSLVIVAPETVAAAALDVARIGSSIGVANSAAAGSTTSVLAAGADEVSAAIATLFGSHAREYQAISTQVA AFHDRFAQTLSAAVGSYVSAEATNAAPLATLEHNVLNALNAPTQALLGRPLIGDGAAGAPGTGQAGGAGG ILWGNGGAGGSGAPGQVGGAGGAAGLFGTGGAGGAGGAGAAGGAGGSGGWLLGNGGVGGAGGQSLLGGAT GGAGGNAGLFGVGGTGGPGGPGGPGGPGGPGGPGGVGGTGGAGGLGGTLYGAGGHGGAGGPGPIGGVGGH GGVGGAAGLLGVGGHGGAGGHGAAGIAGAAGKGGIFPDGSNGGAGGDAGDGGTGGRGGWLAGAGGAGGDG GIGGTGGAGGAGFSRALIVAGDNGGDGGNGGMGGAGGAGGPGGAGGLISLLGGQGAGGDGGDGGAGGVGG DRGAGANGNQAVNAGAGGAGGHGGDPGAGGAGGTGGAGSTIGAHGAAGASPTSGGNGGAGGNGAHFSSGG KAGGNGGAGGAGGLVGNGGAGGAGGNGAPGAPPSGGDPNGGGGGAGGAGGKGGDGGAQAGDGGAGGAGGK GGNGGNGATGATGLNGLGAGADGTDGGKGGNGGAGGGGGAGGQGGKALAATHQDGSMGAGGAGGNGGAGG MGGDGGNGAKGTFDNGGDGVGGNGGNGGSRGIGGAGGIGGAGSTAGADGARGATPTSGGNGGTGGNGANA TVAGGAGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGSSPTTAGESGTSGQNGGAGGAGGAGGRGGDFGG DGGTGGAGGNGADGGAGGNGANGANATTPGAKGGDGGHGGPGAQGGNGGQGGPGGLAGNLFGQNGIQGVG GSGGKGGAGGLAGDGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSGGAGSTPGAKGAHGFTPTSGGDG GDGGNGGHSQVVGGNGGDGGNGGNGGSAGTGGNGGRGGDGAFGGMSANATNPGENGPNGNPGGNGGAGGA GGAGLNGGNGGAGGNGGLGGFGGNGAAGANGVAVGAPGQPGGAGGHGGAGGNGGAGGNGGQGVVSDGAGG AGGAGGDGGAPGDGANGGNGQGAGAFAGGGGGRGGDGGNAGNAGAGGPGGTGSTAGKAGPAGSILHDGGN GGHGGHGAASGGNGGPGGHGGNGGNGGTGANGGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGGNGGR GGNGGQGLTGAGGNGGTGGTPGNGGNGGNGASGDLVTSPGDGGGGGRGGDAGRGGDAGLGGSSGPGGTPG DWGTGGTGGTGGTGGQGANGGLTGGRGGTGGNGGAGGTGGTGHNGSQPGMGGNGGAGGFGGNGFAGVGGR GGMGGSGGTGGTGDAGPFGTGTGGTGGHGGQGGGGGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFG GLGGGEFV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1485c | PE_PGRS27 | - | 100% (1408) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb3541 | PE_PGRS55 | 0.0 | 49.32% (1693) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb0593c | PE_PGRS7 | 0.0 | 51.40% (1430) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-178 | 46.01% (828) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv1450c | PE_PGRS27 | 0.0 | 87.10% (1248) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 2e-11 | 33.95% (162) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_4284c | - | 6e-51 | 31.49% (543) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_3763 | - | 0.0 | 56.10% (1542) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 5e-25 | 43.02% (172) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-178 | 41.67% (1099) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 6e-47 | 38.91% (329) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 47.59% (1162) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-173 | 45.10% (827) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb1485c|M.bovis_AF2122/97 ------------MSLVIVAPETVAAAALDVARIGSSIGVANSAAAGSTTS Rv1450c|M.tuberculosis_H37Rv ------------MSLVIVAPETVAAAALDVARIGSSIGAANAAAAGSTTS MMAR_3763|M.marinum_M ------------MSFVSVAPEAVATAASDLARIGSSIDAVNAAAAGATTT MUL_4367|M.ulcerans_Agy99 ------------MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------MSIIDFILNLFRDPVEAASYVADPEAALANAG-- MAV_4827|M.avium_104 -------------------MNIVLGVSMAPSSIQMVVLEGEYADG----- MLBr_01556|M.leprae_Br4923 ------------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASS- Mb1485c|M.bovis_AF2122/97 VLA----------AGADEVSAAIATLFG----SHAREYQAIST--QVAAF Rv1450c|M.tuberculosis_H37Rv VLA----------AGADEVSAAIATLFG----SHAREYQAIST--QVAAF MMAR_3763|M.marinum_M VLA----------AGADEVSVAIAALFG----THAQEYQAIST--RISAL MUL_4367|M.ulcerans_Agy99 VLP----------AAGDEVSAAIAELFG----GFGREYQAMGA--RVALL Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ------------------------MMFL----APPGGPGPISA--AIQLT MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------LSAVSAAQVGAVMPVVAESVASNYGYQSQWVN MAV_4827|M.avium_104 ---------------------------------ATVEEDAIDVTGADDAA MLBr_01556|M.leprae_Br4923 ------------------------------TVEAPVARRLRESFGGIKPA Mb1485c|M.bovis_AF2122/97 HDRFAQTLSAAVGSYVSAEATNAAPLATLEHNVLNALNAPTQ-------- Rv1450c|M.tuberculosis_H37Rv HDRFAQTLSAAVGSYVSAEATNAAPLATLEHNVLNALNAPTQ-------- MMAR_3763|M.marinum_M NERFVALLTAGNNSYAASESASVSWLQAVEQDVLGLVNAPSQ-------- MUL_4367|M.ulcerans_Agy99 HDDFVRALTAGGSAYGQAEALNMWPLQELEQQALGVVNAPSM-------- Mflv_5091|M.gilvum_PYR-GCK -----------MVTFGGGATPTPTSLGAAAVDLSGTSCG----------- Mvan_1264|M.vanbaalenii_PYR-1 STGSEATEPWYVVSFGGSGAPTPNNLAASLVDLSGTSCG----------- MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 TGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPR---------------- MAV_4827|M.avium_104 TASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALR------- MLBr_01556|M.leprae_Br4923 ADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP------- Mb1485c|M.bovis_AF2122/97 -------------------------------------------------- Rv1450c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3763|M.marinum_M -------------------------------------------------- MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 ----------------------------------ALLGRPLIGDGAAGAP Rv1450c|M.tuberculosis_H37Rv ----------------------------------ALLGRPLIGDGAAGAP MMAR_3763|M.marinum_M ----------------------------------NWFGRPLIGNGADGVA MUL_4367|M.ulcerans_Agy99 ----------------------------------ALFGRPSIGNGVDGVA Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------LICNGQD--- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------LICNGQD--- MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGING-T TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------DNDFLSHNDTDFA MAV_4827|M.avium_104 --------------------------------------DALAARRIDNVM MLBr_01556|M.leprae_Br4923 ------------------------------------VQVDHSAAVVPIVA Mb1485c|M.bovis_AF2122/97 GTGQAGGAGGILWGNGGAGG-SGAPGQVGGAGGAAGLFGTGGAGGAG--- Rv1450c|M.tuberculosis_H37Rv GTGQAGGAGGILWGNGGAGG-SGAPGQVGGAGGAAGLFGTGGAGGAG--- MMAR_3763|M.marinum_M GTGQAGGAGGILWGNGGAGG-SGAVGQSGGAGGSAGLLGHGGAGGAGGQA MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAG--- Mflv_5091|M.gilvum_PYR-GCK GTGQN---GGILFGNGGSGWNSDVVGMDGGNGGNGGLFG--GNGGNG--- Mvan_1264|M.vanbaalenii_PYR-1 GTGQN---GGILFGNGGSGWNSEIAGVSGGNGGNAGLFG--GNGGNG--- MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVG--- TH_3810|M.thermoresistible__bu ------------------------VDGDGGSGGRTGLFSKLSRGGDG--- MAB_4284c|M.abscessus_ATCC_199 SHNPIASGNQVMSPSGNVDSFNRGPLLDLSFG--DLQFGNRDTTAIG--- MAV_4827|M.avium_104 LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP--- MLBr_01556|M.leprae_Br4923 GEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTG--- . Mb1485c|M.bovis_AF2122/97 ---GAGAAGGAGGSGGWLLGNGGVG------------------------- Rv1450c|M.tuberculosis_H37Rv ---GAGAAGGAGGSGGWLLGNGGVG------------------------- MMAR_3763|M.marinum_M GASGTGGVGGAGGAGGWLYGNGGTGGVGGEGPVNGGVGGAGGRAWLLGAG MUL_4367|M.ulcerans_Agy99 ---GVGAAGMTGGSG----------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---GNGLGGGNGGNG----------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ---GNGLGSGDGGNG----------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ---WAGLDGGNGGSG----------------------------------- TH_3810|M.thermoresistible__bu ---GDGGLGGNGGHG----------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----DGAVAVGGSNS----------------------------------- MAV_4827|M.avium_104 --DVYKQQIRAESYG----------------------------------- MLBr_01556|M.leprae_Br4923 --PHPGPAPKPGGRP----------------------------------- . Mb1485c|M.bovis_AF2122/97 ---GAGGQSL-LGGATGGAGGNAGLFGVGGTG------------GPGGPG Rv1450c|M.tuberculosis_H37Rv ---GAGGQSL-LGGATGGAGGNAGLFGVGGTG------------GPGGPG MMAR_3763|M.marinum_M GSGGAGGQGLGLNGGAGGAGGNGGLFGIGGTGGAGGDSAGSGSAGAGGDG MUL_4367|M.ulcerans_Agy99 ----------------GAGGGGGWLWGAGGSG------------------ Mflv_5091|M.gilvum_PYR-GCK -----------------GNAGAFALFGNGGNG------------------ Mvan_1264|M.vanbaalenii_PYR-1 -----------------GDAGLFSLFGRGGNG------------------ MSMEG_0868|M.smegmatis_MC2_155 ----------------------GLLMGIGGAG------------------ TH_3810|M.thermoresistible__bu ----------------------------GGTG------------------ MAB_4284c|M.abscessus_ATCC_199 -----------------------GPIASG--------------------- MAV_4827|M.avium_104 -------------------------DAAGQLS------------------ MLBr_01556|M.leprae_Br4923 -------------------------PRVGNNP------------------ * Mb1485c|M.bovis_AF2122/97 GPGGPGGPGGPGGVG---------GTGGAGGLGGTLYGAGGHGGAGGPGP Rv1450c|M.tuberculosis_H37Rv G---------PGGVG---------GTGGAGGLGGTLYGAGGHGGAGGPGP MMAR_3763|M.marinum_M GHGGLWGRGGAGGIGGVNSDSGDGGAGGGGGAGGRLFGSGGAGGAGGTGA MUL_4367|M.ulcerans_Agy99 --------GAAG-------------AGGSGGSGGWLWGNAGQTAGAG--- Mflv_5091|M.gilvum_PYR-GCK ---------------------------GNGGVG----------------- Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------GNGGVG----------------- MSMEG_0868|M.smegmatis_MC2_155 ------------------------GAGGVGADGTSAHVDGGTGGTGGTG- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 IGGVGGHGGVGGAAG-LLGVGGHGGAGGHGAAGIAGAAGKGGIFPDGSNG Rv1450c|M.tuberculosis_H37Rv IGGVGGHGGVGGAAG-LLGVGGHGGAGGHGAEGVAGAAG-EDLSPHGTSG MMAR_3763|M.marinum_M VAGSGGDGGAGGAAVGLWGLGGHGGAGGDGAVGLAGGVG--------EAG MUL_4367|M.ulcerans_Agy99 VGGAGGAGGAGDAGD--QGVSG-VAPGEAGAVGFAGGAG----------- Mflv_5091|M.gilvum_PYR-GCK VVGATGAVGAPGVAG------------ATGATGVTSGVV----------- Mvan_1264|M.vanbaalenii_PYR-1 IAGATGAVGAPGVAG------------ATGATGVTSNVT----------- MSMEG_0868|M.smegmatis_MC2_155 -GGTGGTGGIGGTGG-----GLFGLLGHSGSTGAAGAAG----------- TH_3810|M.thermoresistible__bu ------------------------------IISLLSLAG----------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------QGSTAVNGDVR----------- MAV_4827|M.avium_104 -------------------------AMVAGLEKLESLPG----------- MLBr_01556|M.leprae_Br4923 ---------------------------FSSAQSVARPIP----------- Mb1485c|M.bovis_AF2122/97 GAGGDAGDGGTGGRGGWLAGAGGAGGDGGIGGTGGAGGAGFSRALIVAGD Rv1450c|M.tuberculosis_H37Rv GVGGDAGDGGTGGRGGWLAGAGGAGGAGGVGGTGGAGGAGFSRALIVAGD MMAR_3763|M.marinum_M GEGGSAGNGGAGGLGGWLIGSGGAGGLGGVGGAGGAGGAG--AAGIAPGS MUL_4367|M.ulcerans_Agy99 GAGGAGGNGVGGG----VNGAGGAGGAGGVGGGGGAGASG-----VGAGV Mflv_5091|M.gilvum_PYR-GCK --GGNGED---------AVGYGATGAAGAAGAAGAAGAAG---------- Mvan_1264|M.vanbaalenii_PYR-1 --GGNGAD---------AVGYGATGAAGAAGAAGAAGKAG---------- MSMEG_0868|M.smegmatis_MC2_155 -NGGDGGNGGFG--YVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPG- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------DSNIINADHGSNVGVDQSQ---------- MAV_4827|M.avium_104 -------------------------GLLLVGSGVDVAP------------ MLBr_01556|M.leprae_Br4923 --------------RPPAPRPSASPSSMSPRPGGAVGGGG---------- Mb1485c|M.bovis_AF2122/97 NGGDGGNGGMGGAGGAGGPGGAGGLISLLGGQGAGGDGGDGGAGGVGGDR Rv1450c|M.tuberculosis_H37Rv NGGD---------------------------------------------- MMAR_3763|M.marinum_M NGGNGGNGGVGGAGGVGGSGGQGGFLRFLGGQGDGGAGGAGGAGGVAGDG MUL_4367|M.ulcerans_Agy99 AGGDGGTG------------------------------------------ Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GAGANGNQAVNAGAGGAGGHGGDPGAGGAGGTGGAGSTIGAHGAAGASPT Rv1450c|M.tuberculosis_H37Rv -----------------------PGAGGAGGTGGAGSTIGAHGAAGASPT MMAR_3763|M.marinum_M GKGADAAAFSG-AAGGNGGHGGDNGAGGAGGTGGAGSTVGAHGADGFSPI MUL_4367|M.ulcerans_Agy99 ------------------------GAGGAAGVGGAAGTGGTGGAAGVAGT Mflv_5091|M.gilvum_PYR-GCK -------------------------AVGSAGAAGEAGETGTWGNAGLPGK Mvan_1264|M.vanbaalenii_PYR-1 -------------------------AVGSAGTAGSAGAPGVWGNAGLPGA MSMEG_0868|M.smegmatis_MC2_155 ------------------------KGGGGGGGGGGAILIGANGGTVDGHA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------------TRVGGDYTNVSGHGSADIDKS MAV_4827|M.avium_104 ----------------------------LKQVLQTTTFLDVSVAEEPETA MLBr_01556|M.leprae_Br4923 ---------------------------PRPPRTGVPRPGGGRPGAPVGGR Mb1485c|M.bovis_AF2122/97 SGGNGGAGGNGAH--FSSGGKAGGNG-----GAGGAGGLVGNGGAGGAGG Rv1450c|M.tuberculosis_H37Rv SGGNGGAGGNGAH--FSSGGKAGGNG-----GAGGAGGLVGNGGAGGAGG MMAR_3763|M.marinum_M TGGNGGDGGNGASGPAASAGVAGGAG-----GAGGDGGLYGNGGAGGDGG MUL_4367|M.ulcerans_Agy99 GGDGGDGGAGGAGSDASLAGQAGFAG-----GSGGAGGVGGSAGAGGVNG Mflv_5091|M.gilvum_PYR-GCK AGDAGGAGAVGAAGAAGTVGTAGATG-----GTG---------------- Mvan_1264|M.vanbaalenii_PYR-1 AGAAGGAGAIGTAGVAGAAGTAGATG-----GTG---------------- MSMEG_0868|M.smegmatis_MC2_155 IGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHST TH_3810|M.thermoresistible__bu ---NGGNGGNGYRTTDNNALDGGHGG------------------------ MAB_4284c|M.abscessus_ATCC_199 VTVVDDHSQRNTTNINDSFNTDRSTN------------------------ MAV_4827|M.avium_104 LARGAALAAANAPLFASSTAALAYAQ------------------------ MLBr_01556|M.leprae_Br4923 SDAGGGNYRGGGVGALPGGGSGGFRG------------------------ . Mb1485c|M.bovis_AF2122/97 NGAPG-----APPSGGD-PNGGGGGAGGAGGKGGDGGAQAGD-GGAGGAG Rv1450c|M.tuberculosis_H37Rv NGAPG-----APPSGGD-PNGGGGGAGGAGGKGGDGGAQAGD-GGAGGAG MMAR_3763|M.marinum_M NGVAGGQGADATAAGASGENGGDGGAGGMGGAGGMGGVLGGH-GGAGGIG MUL_4367|M.ulcerans_Agy99 S-------------------GGDGGAGAAGGAGGASATVAGS-GGVGGDG Mflv_5091|M.gilvum_PYR-GCK -------------------TGANGGAGGVGGVGGTG-AAGAA-GGAGGLG Mvan_1264|M.vanbaalenii_PYR-1 -------------------VGGNGGAGQAGGIGGTG-AAGAA-GQAGTAG MSMEG_0868|M.smegmatis_MC2_155 GTG----------------IGGNGGIGSVYAYGNNGAVSGTATGGRGGDG TH_3810|M.thermoresistible__bu -------------------NGGNVGFFSLFNLGGAG--------GWGGSG MAB_4284c|M.abscessus_ATCC_199 ---------------------IGSGNTTNTEIGSHNQANIGTSTSAGGSA MAV_4827|M.avium_104 ----------------------DPGTGAVDQYSLPDYLYVPVDPEPGDDE MLBr_01556|M.leprae_Br4923 --------------------RPGGGGHGGGGRPGQRGGAAGAFGRPGGAP . * * Mb1485c|M.bovis_AF2122/97 GKGGNGGNGATGATGLNGLGAG-ADGTDGGKGGNGGAGGGGGAGGQGGKA Rv1450c|M.tuberculosis_H37Rv GKGGNGGNGATGATGLNGLGAG-ADGTDGGKGGNGGAGGGGGAGGQGGKA MMAR_3763|M.marinum_M GVGATGGSGGLGATGAEGVTGGNLHGGDGGNGGKGGIGGAGGDGGAGGKA MUL_4367|M.ulcerans_Agy99 GAGGAAG-GGVGAASLG------------GDGGHAGAGGAGGEGLSGG-- Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG-----------------GQGTAGGTGGVGG-------- Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG-----------------GQGTEGGTGGVGG-------- MSMEG_0868|M.smegmatis_MC2_155 IDGGTGGAGGMGEIYSG----------ADGEATGISAGGDGGSATGADSL TH_3810|M.thermoresistible__bu VDG---------------------------------VDVVGG-------- MAB_4284c|M.abscessus_ATCC_199 AVGGNAG-----------------------LAGNAGLAGNAG-------- MAV_4827|M.avium_104 LAYSAVG----------------------EEDAESPTVVIEKLFLP---- MLBr_01556|M.leprae_Br4923 RRGRKSKRQKRQ------------------EYDSMQAPVVGGVRLPHGNG Mb1485c|M.bovis_AF2122/97 LAATHQDGSMGAGGAGGNGGAGGMGGDGGNGAKGTFDNGGDGVGGNGGNG Rv1450c|M.tuberculosis_H37Rv LAATHQDGSMGAGGAGGNGGAGGMGGDGGNGAKGTFDNGGDGVGGNGGNG MMAR_3763|M.marinum_M QAAGFADGTEGVGGAGGEGGAGGVAGDGGKGADAAAFSG--AAGGNGGHG MUL_4367|M.ulcerans_Agy99 ----FNTG--AAGGIGGAGGAGGTGGDSG------------GVGGVNGDG Mflv_5091|M.gilvum_PYR-GCK -----------IGGAGSTGAVGGVGGKGIQ-------------GGQGLQG Mvan_1264|M.vanbaalenii_PYR-1 -----------VGGVGATGGAGGVGGKGIQ-------------GGQGLQG MSMEG_0868|M.smegmatis_MC2_155 GGRGGTSWVQAGYGPTTGGKASGTAKAGHG-----------GKASDGGKG TH_3810|M.thermoresistible__bu ---------------NPDGGTPGAHGESHT---------------PGVYT MAB_4284c|M.abscessus_ATCC_199 --------------LAGNAGLAGNAGLAGN----------------AGLA MAV_4827|M.avium_104 --------------EDSEPRRRPVLLVGSG---------------LAVVG MLBr_01556|M.leprae_Br4923 ETIRLARGASLSDFAEKIDANPAALVQALFNLG-----EMVTATQSVGDE . Mb1485c|M.bovis_AF2122/97 GSRGIGGAGGIGGAGSTAGADGARGATPTSGGNGGTGGNGAN--ATVAGG Rv1450c|M.tuberculosis_H37Rv GSRGIGGAGGIGGAGSTAGADGARGATPTSGGNGGTGGNGAN--ATVAGG MMAR_3763|M.marinum_M GDNGAGGAGGTGGAGSTVGAHGADGFSPITGGNGGDGGNGASGPAASAGV MUL_4367|M.ulcerans_Agy99 GAGGGGGRGGDGGSSTSTSG---------VGGAGGAGGNGGN-------- Mflv_5091|M.gilvum_PYR-GCK GKGGDGGAGGKGGDADSMGS---------AGATGGKGGNGGN-------- Mvan_1264|M.vanbaalenii_PYR-1 GQGGDGGTGGTGGDATSMGE---------AGATGGKGGNGGN-------- MSMEG_0868|M.smegmatis_MC2_155 GNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHG TH_3810|M.thermoresistible__bu DRQGEDGEDGTG------------------TGIGGRGGNGGS-------- MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAGN----------AGLAGNAGLAGN-------- MAV_4827|M.avium_104 ISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAPP-------- MLBr_01556|M.leprae_Br4923 TLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDE-------- . Mb1485c|M.bovis_AF2122/97 AGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGSSPTTAGESGTSGQNGGA Rv1450c|M.tuberculosis_H37Rv AGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGSSPTTAGESGTSGQNGGA MMAR_3763|M.marinum_M AGGAGGAGGDGGLYGNGGAGGDGGNGVAGGQGADATAAGASGENGGDGGA MUL_4367|M.ulcerans_Agy99 AGFGVSAGGTGGSAGDGGAGG-GAGGVDGVGGAS-----------GNGGA Mflv_5091|M.gilvum_PYR-GCK -------GGRGGLFGKGGNAGNGADGGTG----------------GAGGA Mvan_1264|M.vanbaalenii_PYR-1 -------GGRGSLFGRGGNAGNGGNGGTG----------------GNGGN MSMEG_0868|M.smegmatis_MC2_155 SITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGN TH_3810|M.thermoresistible__bu -------SSGTHPMAEDGEHVKALDGRPG----------------LDGGN MAB_4284c|M.abscessus_ATCC_199 -------AGLAGNAGLAGNAGLAGNAGLAG----------------NAGL MAV_4827|M.avium_104 --------PVQASAPQPKISVPEPVAAPKP---------------LSPPV MLBr_01556|M.leprae_Br4923 ------LQVRPPVVTVMGHVDHGKTRLLDTIRKAN---------VREAEA Mb1485c|M.bovis_AF2122/97 GGAGGAGGRGGDFGGDGGTGGAGGNGADGGAGGNGANGANATTPG-AKGG Rv1450c|M.tuberculosis_H37Rv GGAGGAGGRGGDFGGDGGTG---------GAGGNGANGANATTPG-AKGG MMAR_3763|M.marinum_M GGMGGAGGMGGVLGGHGGAGGIGGVGATGGSGGLGATGAEGVTGGNLHGG MUL_4367|M.ulcerans_Agy99 AGAGGAGGSGIGAGIDGGAG---------GAGGTG--GAAGFPGG---GG Mflv_5091|M.gilvum_PYR-GCK GGTGGTGG-------AGGTG---------GTGGTGGIGGAGSTGG--TGG Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGG-------NGGTG---------GTGGTGGIGGAGSTGG--TGG MSMEG_0868|M.smegmatis_MC2_155 GGDGGFNGTGGATGGRGGDG---------AGASVWKANGQHSTGQTDTGG TH_3810|M.thermoresistible__bu GSHG---------------------------------------------G MAB_4284c|M.abscessus_ATCC_199 AGNAGLAG---------------------------------------NAG MAV_4827|M.avium_104 AAPLPAAP---------------------PPAAPPLPEAPPIPAAPPVVP MLBr_01556|M.leprae_Br4923 GGITQHIGAYQVGVDLDGSER--------LITFIDTPGHEAFTAMRARGA .. Mb1485c|M.bovis_AF2122/97 DGGHGGPGA---QGGNGGQGGPGGLAGNLFGQNGIQGVGGSGGKGGAGGL Rv1450c|M.tuberculosis_H37Rv DGGHGGPGA---QGGNGGQGGPGGLAGNLFGQNGIQGVGGSGGKGGAGGL MMAR_3763|M.marinum_M DGGNGGKGG---IGGAGGDGGAGGKAQAAGFADGTEGAGGAGGEGGAGGV MUL_4367|M.ulcerans_Agy99 TTGAWGTGG---AGGAGGAGGAGDHGGVGVNPGDSGTAGWAGGAGGAGGA Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGG---TGGTGGTGGTG-------------GTGGTGGKGGTGGT Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGG---TGGTGGTGGTG-------------GTGGTGGKGGTGGT MSMEG_0868|M.smegmatis_MC2_155 NGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGAL TH_3810|M.thermoresistible__bu NGGHGGRGG-------------------------FLGIGGSGGWGG---- MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAG-------------------------NAGLAGNAGLAGNAAV MAV_4827|M.avium_104 VPVVVPPVP----------------------VPVPVRIPVPDPVSPPQLL MLBr_01556|M.leprae_Br4923 KATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAK . Mb1485c|M.bovis_AF2122/97 AGDGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSGGAGSTPGAKGAHG Rv1450c|M.tuberculosis_H37Rv AGDGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSGGAGSTPGAKGAHG MMAR_3763|M.marinum_M AGDGGKGAD-AAAFSGAAGGNGGHGGDNGAGGAGGTGGAGSTVGAHGADG MUL_4367|M.ulcerans_Agy99 GG--------SAAFNGVNG-AGGAGGNGGAGGGGGAGASGIGAGVAGGDG Mflv_5091|M.gilvum_PYR-GCK GG------------------AGGTGGDGGTGGTGGTGGTGGTGGTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 GG------------------DGGTGGTGGTGGTGGTGGTGGTGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 GG--------NGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGG TH_3810|M.thermoresistible__bu --------------------HGGNGGDTDADG------------------ MAB_4284c|M.abscessus_ATCC_199 AG------------------NAAVAGNAAVAGNAAVGGVLNTGVSGAIGG MAV_4827|M.avium_104 AP-------------------PRLSVPQPVQPPVRVPQPPSPPQVGGTVP MLBr_01556|M.leprae_Br4923 IRG---------QLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLL . Mb1485c|M.bovis_AF2122/97 FTPTSGGDGGDGGNGGH--------------------------------- Rv1450c|M.tuberculosis_H37Rv FTPTSGGDGGDGGNGGN--------------------------------- MMAR_3763|M.marinum_M FSPTTGGNGGDGGSGGSGFQGVKGGAGGVGGDGGLYGNGGTGGTGGTGGI MUL_4367|M.ulcerans_Agy99 GTGGTGGAAGTGGAAGT--------------------------------- Mflv_5091|M.gilvum_PYR-GCK AGDGTGGTGGTGGTGGQ--------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 AGDGLGGTGGTGGTGGF--------------------------------- MSMEG_0868|M.smegmatis_MC2_155 NGGAGRIRVNNGTATGT--------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SSHVGGAINESLGGSGS--------------------------------- MAV_4827|M.avium_104 QSPPQHQTPPGEGTPPK--------------------------------- MLBr_01556|M.leprae_Br4923 TADAALDLRANSGMEAQG-------------------------------- Mb1485c|M.bovis_AF2122/97 ----SQVVGG---------------------------------------- Rv1450c|M.tuberculosis_H37Rv ----SQVVGG---------------------------------------- MMAR_3763|M.marinum_M GFNGSTTIGGGNGGDGHTGLTGGDGGAGGKGGALAGHGGDGGTGGVGGTG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 -----------------NGGDGGNGGNGGSAGT-GGNGGRG--------- Rv1450c|M.tuberculosis_H37Rv -----------------NGGDGGNGGNGGSAGT-GGNGGRG--------- MMAR_3763|M.marinum_M GTGGSGGTGTSGIFSSANGGDGGNGGDGGTGGT-GGVGGLGGQAQAAGFA MUL_4367|M.ulcerans_Agy99 ------------------GGTGGAAGAAGSAGD-GGAGGAG--------- Mflv_5091|M.gilvum_PYR-GCK ------------------GGQGGQGGTGGTGGQ-GGLGGGG--------- Mvan_1264|M.vanbaalenii_PYR-1 ------------------GGQGGQGGTGGTGGQ-GGLGGVG--------- MSMEG_0868|M.smegmatis_MC2_155 ----------------ATGGNGGNGGNGDADGHRGGKGGDG--------- TH_3810|M.thermoresistible__bu -------------------GNGGDGGNGGSAGR-GGTGGLR--------- MAB_4284c|M.abscessus_ATCC_199 -----------------VGGSTAVGGGAHTGVGGGVSTGVG--------- MAV_4827|M.avium_104 -----------------PDGPGNYGGGHVPTPGAGGSGGSG--------- MLBr_01556|M.leprae_Br4923 --------------VAIEAHLDRGRGPVATVLVQRGTLRIG--------- * . Mb1485c|M.bovis_AF2122/97 -------GDGAFGGMSANATNPGE-------------------------- Rv1450c|M.tuberculosis_H37Rv -------GDGAFGGMSANATNPGE-------------------------- MMAR_3763|M.marinum_M DGTQGVGGAGGVGGTGGNAGNGGHGANADVGSGKAGGNGGDGGDPGVGGI MUL_4367|M.ulcerans_Agy99 -------GAGDDGSAGVVSGDPGT-------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 ------------------------------NGPNGNPGGNGGAGGAGGAG Rv1450c|M.tuberculosis_H37Rv ------------------------------NGPNGNPGGNGGAGGAGGAG MMAR_3763|M.marinum_M GGQGGAGSIAGVEGAAGVAPTSGGNGGDGGNGASGATGVNGGAGGSGGDG MUL_4367|M.ulcerans_Agy99 ---------------------------------AGKAGGAGGAGGVGGNG Mflv_5091|M.gilvum_PYR-GCK --------------------------------------GTGGQGGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------GTGGTGGTGGTG MSMEG_0868|M.smegmatis_MC2_155 ----------------------------------GEALIRATVIGSNASG TH_3810|M.thermoresistible__bu -----------------------------------------GVFGINGGN MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------VGSHVGGG MAV_4827|M.avium_104 ----------------------------------------GGHVPTPGAG MLBr_01556|M.leprae_Br4923 ----------------------------------------DSVVAGDAYG . . Mb1485c|M.bovis_AF2122/97 ---LNGGNGGAGGNGGLG-------------------GFGGNGAAGANGV Rv1450c|M.tuberculosis_H37Rv ---LNGGNGGAGGNGGLG-------------------GFGGNGAAGANGV MMAR_3763|M.marinum_M GLYGNGGDGGDGGNGGKGQVGSTGPVAGSAGGTGGTGGTGGQGGAGGSGG MUL_4367|M.ulcerans_Agy99 ---VAGGVNGSGGAGGAG-------------------GAGGTGGAGASGV Mflv_5091|M.gilvum_PYR-GCK ------GQGGTGGTGGTG-------------------GTGGTGGAGG--- Mvan_1264|M.vanbaalenii_PYR-1 ------GQGGTGGTGGTG-------------------GTGGTGGAGG--- MSMEG_0868|M.smegmatis_MC2_155 --TATGGDGGNGGTLGATN------------------GTGGAATIVAYNV TH_3810|M.thermoresistible__bu ------GRAGLGGRGXXX-------------------------------- MAB_4284c|M.abscessus_ATCC_199 ISESLGGSGSVGGSTAVG-------------------------------- MAV_4827|M.avium_104 ------GSGGSGGGHVPT-------------------------------- MLBr_01556|M.leprae_Br4923 RVRRMVDEHGVDIEAALP-------------------------------- . . . Mb1485c|M.bovis_AF2122/97 AVGAPGQPG-GAGGHGGAGGNG---------------------------- Rv1450c|M.tuberculosis_H37Rv AVGAPGQPG-GAGGHGGAGGNG---------------------------- MMAR_3763|M.marinum_M ALAGHGGDG-GSGGDGGTGGTGGTGRNGANGITGADIDGGSGGKGGNGGT MUL_4367|M.ulcerans_Agy99 PASVDGGDG-GAGGAGGAAGTG---------------------------- Mflv_5091|M.gilvum_PYR-GCK ----DGGLG-GLGGFGGSGGTG---------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----DGGLG-GLGGFGGVGGTG---------------------------- MSMEG_0868|M.smegmatis_MC2_155 VQANPQASGTATDGHGGSGING---------------------------- TH_3810|M.thermoresistible__bu -------XG---GGVGAAVRSG---------------------------- MAB_4284c|M.abscessus_ATCC_199 --------GGAHTGVGGGVSTG---------------------------- MAV_4827|M.avium_104 ------------PGTGGPGGTG---------------------------- MLBr_01556|M.leprae_Br4923 ------SSPVQVIGFTSVPGAG---------------------------- * . * Mb1485c|M.bovis_AF2122/97 -GAGGNGGQG------VVSDGAGGAGGAGGDGGAPGDGANGGNGQGAGAF Rv1450c|M.tuberculosis_H37Rv -GAGGNGGQG------VVSDGAGGAGGAGGDGGAPGDGANGGNGQGAGAF MMAR_3763|M.marinum_M GGAGGAGGQGGQAQAAGYSDGTQGVGGAGGDGGTAGIGGDGGDGANAVAG MUL_4367|M.ulcerans_Agy99 -GSGGSAGNT----------GAGGAGGAGGAGGSAASTGVNGDG------ Mflv_5091|M.gilvum_PYR-GCK -GQGGLGGPG------------GSTGGAGGAGGQAGTAGKGG-------- Mvan_1264|M.vanbaalenii_PYR-1 -GQGGQGGPG------------GSTGGAGGAGGQAGVAGKGG-------- MSMEG_0868|M.smegmatis_MC2_155 -GHGGNGGQG-----TIEANGPSAVASGIGAGGNGGDGIDGGLG------ TH_3810|M.thermoresistible__bu ------------------------NGVFSGGGGTPSAG------------ MAB_4284c|M.abscessus_ATCC_199 ----------------------VGVGSHVGGGISESLGGSGSVG------ MAV_4827|M.avium_104 -------------------------GSGGGHVPTPGAGTPGGSG------ MLBr_01556|M.leprae_Br4923 -DNFLVVDED---------RIARQIADRRSARKRNALAARSRKR------ . . . Mb1485c|M.bovis_AF2122/97 AGGGGGRGGDGGNAGNAGAGGPGGTGSTAGKAGPAGSILHDGGNGGHGGH Rv1450c|M.tuberculosis_H37Rv AGGGGGRGGDGGNAGNAGAGGPGGTGSTAGKAGPAGSILHDGGNGGHGGH MMAR_3763|M.marinum_M SGERGGDGGHGGDPGNAGAGGQAGAGPTSGGNGKAGSGVTTGGNGGDGGD MUL_4367|M.ulcerans_Agy99 -----------------GAGGAGGVG------GLGGDSAATAGGGGAGGD Mflv_5091|M.gilvum_PYR-GCK -----------------LFGGSGSAG----KAGATGAAGASGGKGAQGAT Mvan_1264|M.vanbaalenii_PYR-1 -----------------LFGGSGSAG----TAGVTGASGASGGKGAQGAT MSMEG_0868|M.smegmatis_MC2_155 -----------------GNGGDGVVNTTANAANPGSATGTATGGDGGKAT TH_3810|M.thermoresistible__bu -------------------------------FGVPTTIQFPAGSCTSRAV MAB_4284c|M.abscessus_ATCC_199 -----------------------------GSTAVGGGAHTGVGGGVNTGV MAV_4827|M.avium_104 ----------------------------------GGHLPFPGAGSTPGGS MLBr_01556|M.leprae_Br4923 --------------ISLEDLDSALKETSQLNLILKGDNAGTVEALEEALM Mb1485c|M.bovis_AF2122/97 G-----------AASGGNGGP----GGHGGNGGNGGTG------------ Rv1450c|M.tuberculosis_H37Rv G-----------AASGGNGGP----GGHGGNGGNGGTG------------ MMAR_3763|M.marinum_M GGSGAIGVKGGAGGAGGDGGL----YGNGGNGGDGGTGGKGTVGDSGATL MUL_4367|M.ulcerans_Agy99 G---------------GKGGA----GGAGVNGVGGGDG------------ Mflv_5091|M.gilvum_PYR-GCK G---------------AQGAT----GAQGATGATGAAG------------ Mvan_1264|M.vanbaalenii_PYR-1 G---------------AQGAT----GAQGATGATGASG------------ MSMEG_0868|M.smegmatis_MC2_155 G----------TASQGGNGGPSWVQSGYGSTLGGNATG------------ TH_3810|M.thermoresistible__bu S-------------------------REGIMPSSRAAS------------ MAB_4284c|M.abscessus_ATCC_199 G--------------------------VGSHVGGGISES----------- MAV_4827|M.avium_104 G------------------------GGHLPTPGAGTPG------------ MLBr_01556|M.leprae_Br4923 G------------------------IQVDDEVALRVIDR----------- . Mb1485c|M.bovis_AF2122/97 -----------------------ANGGNGGIGGTGGAGSTGAKG------ Rv1450c|M.tuberculosis_H37Rv -----------------------ANGGNGGIGGTGGAGSTGAKG------ MMAR_3763|M.marinum_M SADGDRGGAGATGGVGGAGGDGGAKGGNGGLGGSGGTGGMGGTGGDGAHG MUL_4367|M.ulcerans_Agy99 --------------------------GKGGTGGAGGAGGAGSDG------ Mflv_5091|M.gilvum_PYR-GCK --------------------------KAGATGAAGAAGAAGSAG------ Mvan_1264|M.vanbaalenii_PYR-1 --------------------------AQGSAGSAGSAGVAGSAG------ MSMEG_0868|M.smegmatis_MC2_155 ----------------------TATAGKGGEASNGGVAGNGGNA------ TH_3810|M.thermoresistible__bu -------------------------------ARAGAACASSTSR------ MAB_4284c|M.abscessus_ATCC_199 ------------------------------LGGSGSVGGSTAVG------ MAV_4827|M.avium_104 -------------------------------GGLGGFGGGHAPAP----- MLBr_01556|M.leprae_Br4923 -----------------------------GVGGITETNVNLASAS----- . Mb1485c|M.bovis_AF2122/97 -----VLGTNEGDGGDGGRGGNGGRGGNGGQG-----------LTGAGGN Rv1450c|M.tuberculosis_H37Rv -----VLGTNEGDGGDGGRGGNGGRGGNGGQG-----------LTGAGGN MMAR_3763|M.marinum_M ADMASGSGANGGYGGYGGFGGVGGAGGTGGVGGQAHAAGFTDGATGAGGD MUL_4367|M.ulcerans_Agy99 -----IIPSNGGLGGNGGNGGNGGQAFGDGVG-------------GAGGI Mflv_5091|M.gilvum_PYR-GCK -----TTGAQGSAGTNGANGANGSQGAAGKAG------------------ Mvan_1264|M.vanbaalenii_PYR-1 -----TTGAQGSAGTNGANGANGSQGAAGKAG------------------ MSMEG_0868|M.smegmatis_MC2_155 --LVMAAGTTGVATGNTATGGDGGAATTAGATG------------GAGGF TH_3810|M.thermoresistible__bu --------SRRSFCCSRA-------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------GGAHTSAINDALGGSGSVGGSTAVG------------------ MAV_4827|M.avium_104 ---------------GGGLGGGGGHAPAPGGG------------------ MLBr_01556|M.leprae_Br4923 -------DAIIIGFNVRAEGKATELASREGVEIR---------------- . Mb1485c|M.bovis_AF2122/97 GGTGGTPGN---GGNGGNGASGDLVTSP------GDGGGGGRGGDAGRGG Rv1450c|M.tuberculosis_H37Rv GGTGGTPGN---GGNGGNGASGDLVTSP------GDGGGGGRGGDAGRGG MMAR_3763|M.marinum_M GGQGGTGGLGAWGGNGGDGADGSISGPPQNGGKGGDGGGGGPGGLGGQGG MUL_4367|M.ulcerans_Agy99 GGKG------------GNAAIGTIVING---------GVGGAGGSGGLGG Mflv_5091|M.gilvum_PYR-GCK -------------------ATGTT----------------GATGAAGEDG Mvan_1264|M.vanbaalenii_PYR-1 -------------------ATGTT----------------GATGAAGDAG MSMEG_0868|M.smegmatis_MC2_155 SNIAAIHG----------AITDSTAISG--------HGGAGNGGNGGKGA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 --------------------------------------YYLVIYQAIDDI Mb1485c|M.bovis_AF2122/97 DAGLGGSSGPGGTPGDWG-TGGTGGTG------------GTGGQGANGG- Rv1450c|M.tuberculosis_H37Rv DAGLGGSSGPGGTPGDWG-TGGTGGTG------------GTGGQGANGG- MMAR_3763|M.marinum_M LSGDGSSTGAAGELGTFG-NGGSGGNGGIGGNATGFNAPGTGGAGGNGGN MUL_4367|M.ulcerans_Agy99 ATEDG--------------VGGVGCAG------------GAGGNGGRGD- Mflv_5091|M.gilvum_PYR-GCK DAG----------------SGGSGING------------GAGGAGGAGG- Mvan_1264|M.vanbaalenii_PYR-1 DPG----------------SEAVDING------------GAGGAGGAGG- MSMEG_0868|M.smegmatis_MC2_155 DGWVQAYDPAGPVGSKIANSSAVAGNG------------GDGGVNGTGG- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------GGAHTSAIN-- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 EKALRGMLKPIYEENQLGRAEIRALFR-------------SSKVGIIAG- Mb1485c|M.bovis_AF2122/97 -------LTGGRGG-----TGGNGG-----------AGGTGGTGHNGSQ- Rv1450c|M.tuberculosis_H37Rv -------LTGGRGG-----TGGNGGNGNTGGT--GGAGGTGGTGHNGSQ- MMAR_3763|M.marinum_M GAFGGSGGTGGRGGSSSVGTGGAGGDGGDGGMGFGGIGGGGGTGGQGGSG MUL_4367|M.ulcerans_Agy99 ----MLFTVGGSGG-----TGGDGGGGGSASG------------------ Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------ASGGDGG-----NGGNTSVWKSGGQ------------------ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 --------PGMGGNGGAGGFGGNGFAGVGGRGGMGGSGGTGGTG--DAGP Rv1450c|M.tuberculosis_H37Rv --------PGMGGNGGAGGFGGNGFAGVGGRGGMGGSGGTGGTG--DAGP MMAR_3763|M.marinum_M VDAQGIGGAGNGGVGGNGGDGGDGWDAPGGQGGKGGQGGNGGDGSPPVPP MUL_4367|M.ulcerans_Agy99 --------SGTGGSGGTGGVGG-----IGGDGKLGGFGGDGGDG------ Mflv_5091|M.gilvum_PYR-GCK ----------EGGEGGDGGKGG-----AGAEGGAGGGGGAGGSG------ Mvan_1264|M.vanbaalenii_PYR-1 ----------EGGEGGAGGAGG-----DGSEGGAGGSGGAGGSG------ MSMEG_0868|M.smegmatis_MC2_155 ------TADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTG------ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------ESMNSSINASHSSSMNESFGSSMGSHGAAGTG--------- MAV_4827|M.avium_104 ---------------------------LGGFGGGHSGGGLGGLG------ MLBr_01556|M.leprae_Br4923 ----------CIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVT Mb1485c|M.bovis_AF2122/97 FGTGTGGTGGHGGQGGGGG----FSILLGLGGLGGLGSPGSIATGTAGGA Rv1450c|M.tuberculosis_H37Rv FGTGTGGTGGHGGQGGGGG----FSILLGLGGLGGLGSPGSIATGTAGGA MMAR_3763|M.marinum_M FGGSSGGTGGTGGTGGAGGDRFVDTELVGIGGAGHGGVTGGGPTGPALVD MUL_4367|M.ulcerans_Agy99 ---GDGGFGVIGGQGGGGG----------FGGLGGTGAGG------APSD Mflv_5091|M.gilvum_PYR-GCK ----AGGAGGAGGSGGSGG---------------------------SGGS Mvan_1264|M.vanbaalenii_PYR-1 ----TGGAGGAGGSGGSGG---------------------------SGGA MSMEG_0868|M.smegmatis_MC2_155 --GTTAGGSGNGGNGGNGG---------------------------NGGA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------FEAQGHAQG---------------------------HASE MAV_4827|M.avium_104 -----------GGHK----------------------------------- MLBr_01556|M.leprae_Br4923 EVREGFECGMTLGYSDIKE----------------------------GDV Mb1485c|M.bovis_AF2122/97 GGGGGFGGLGGGEFV Rv1450c|M.tuberculosis_H37Rv GGGGGFGGLGGGEFV MMAR_3763|M.marinum_M GGTGGAGGSGGTGAH MUL_4367|M.ulcerans_Agy99 KGINGEPGNPG---- Mflv_5091|M.gilvum_PYR-GCK GGSGGAAGDSDD--- Mvan_1264|M.vanbaalenii_PYR-1 GGSGGAAGDSD---- MSMEG_0868|M.smegmatis_MC2_155 DGTPGTAGTTGANNP TH_3810|M.thermoresistible__bu --------------- MAB_4284c|M.abscessus_ATCC_199 TAHTTLPGAEHH--- MAV_4827|M.avium_104 --------------- MLBr_01556|M.leprae_Br4923 IESYELVEKQRA---