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MKFGISTFPNEDTIDPVSLARAVEERGFAALAVAEHTHIPASRESAYPLGGELPKIYYRTLDPFVTLAAA AAVTSEIELITGIALLIQRDPIITAKEAASIDVISGGRFVFGVGAGWNIEELRHHGTDPKTRGALLDERI EAIKVLWTQEPAEYHGRFVDFDASYQRPKPVRKPHPPILIGGDSDATVRRIIRHGAGWIANPLPIDHLSR RIEQIREGAGGDVPLCQFGTPVKPEYWQAAEELGFGQLNLLLPTKSRDVSLRLLDDYAEQVARYIG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1017 | - | - | 100% (276) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_1871 | - | 3e-45 | 38.11% (286) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_1590 | - | 7e-30 | 36.54% (208) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 8e-74 | 51.27% (275) | hypothetical protein Mb3106c |
| M. tuberculosis H37Rv | Rv3079c | - | 8e-74 | 51.27% (275) | hypothetical protein Rv3079c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1059c | - | 8e-46 | 37.81% (283) | hypothetical protein MAB_1059c |
| M. marinum M | MMAR_3559 | - | 1e-127 | 78.47% (274) | hypothetical protein MMAR_3559 |
| M. avium 104 | MAV_1077 | - | 7e-47 | 39.86% (276) | hypothetical protein MAV_1077 |
| M. smegmatis MC2 155 | MSMEG_1996 | - | 1e-120 | 73.91% (276) | N5,N10- methylenetetrahydromethanopterin reductase-related |
| M. thermoresistible (build 8) | TH_2750 | - | 1e-127 | 78.62% (276) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_2792 | - | 1e-116 | 78.46% (246) | hypothetical protein MUL_2792 |
| M. vanbaalenii PYR-1 | Mvan_5819 | - | 1e-137 | 85.40% (274) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3106c|M.bovis_AF2122/97 -----------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAEHTHI
Rv3079c|M.tuberculosis_H37Rv -----------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAEHTHI
Mflv_1017|M.gilvum_PYR-GCK -----------MKFGISTFPNEDTIDPVSLARAVEERGFAALAVAEHTHI
Mvan_5819|M.vanbaalenii_PYR-1 -----------MKFGIATFVNDTTIDPVALARAVEDRGFGSLAVAEHTHI
TH_2750|M.thermoresistible__bu -----------MRFGISTFVNDDTIDPVSLATAIEERGFDALTVAEHTHI
MMAR_3559|M.marinum_M -----------MKFGISTFVNDDSIDPVSLARAIEERGFSSLVIAEHTHI
MUL_2792|M.ulcerans_Agy99 -----------MKFGISTFVNDDSIDPVSLARAIEERGFSSLVIAEHTHI
MSMEG_1996|M.smegmatis_MC2_155 MHTVINSQGTGMKIGISTFVNDDTIDAVTLARAIEERGFHSLVIAEHSHI
MAB_1059c|M.abscessus_ATCC_199 -----------MDYGLVLFTSDRGISPAIAAKAAEDGGFSTFYVPEHTHI
MAV_1077|M.avium_104 ----------------MLFTSDRGISPAAAAKLADDHGFATFYVPEHTHI
* .: *... . :. ** :: :.**:**
Mb3106c|M.bovis_AF2122/97 PVNTQSPYP--GGGPIP-EKYYRTLDPFVALAAAAATTQSLVLGTGIALI
Rv3079c|M.tuberculosis_H37Rv PVNTQSPYP--GGGPIP-EKYYRTLDPFVALAAAAATTQSLVLGTGIALI
Mflv_1017|M.gilvum_PYR-GCK PASRESAYP--LGGELP-KIYYRTLDPFVTLAAAAAVTSEIELITGIALL
Mvan_5819|M.vanbaalenii_PYR-1 PASRESAYP--LGGELP-SIYYRTLDPFVTLAAAAAVTTSIELVTGIALL
TH_2750|M.thermoresistible__bu PASRESPYP--EGGELP-SVYYRTLDPFVTLAAAAAVTSRIQLITGIALL
MMAR_3559|M.marinum_M PASRETPYP--GGGELP-GVYYRTLDPFVTLAAAAAVTSKIELFTGIALL
MUL_2792|M.ulcerans_Agy99 PASRETPYP--GGDELP-GVYYRTLDPFVTLAAAAAVTSKIELFTGIALL
MSMEG_1996|M.smegmatis_MC2_155 PASRESAYP--GGDELP-QKYYRTLDPFVTLAAAAAVTTKIELFTGVALL
MAB_1059c|M.abscessus_ATCC_199 PVKREAAHPGTGGAELPDDRYMRTLDPWVSLGAACAVTSKIRLATAVAIP
MAV_1077|M.avium_104 PIKREAAHPTTGDASLPDDRYMRTLDPWVSLGAACAVTSRVRLSTAVALP
* . ::.:* . :* * *****:*:*.**.*.* : * *.:*:
Mb3106c|M.bovis_AF2122/97 PERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRVI
Rv3079c|M.tuberculosis_H37Rv PERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRVI
Mflv_1017|M.gilvum_PYR-GCK IQRDPIITAKEAASIDVISGGRFVFGVGAGWNIEELRHHGTDPKTRGALL
Mvan_5819|M.vanbaalenii_PYR-1 IQRDPIITAKEAASIDLISNGRFVFGVGAGWNLEELRHHGTDPKTRGALL
TH_2750|M.thermoresistible__bu IQRDPIITAKEAASIDLISDGRFVFGVGAGWNLEEMRHHGTDPRTRGALL
MMAR_3559|M.marinum_M IQRDPITTAKEAASIDLISGGRFVFGVGAGWNIEELRDHGTDPKTRGALL
MUL_2792|M.ulcerans_Agy99 IQRDPITTAKEAASIDLISGGRFVFGVGAGWNIEELRDHGTDPKTRGALL
MSMEG_1996|M.smegmatis_MC2_155 IQRDVIHTAKEAASVDLISNGRFVFGVGAGWNLEEMRNHGTDPKTRGRLL
MAB_1059c|M.abscessus_ATCC_199 VEHDPITLAKSIATLDHMSGGRVTVGVGYGWNTDELADHHVPAGRRRTML
MAV_1077|M.avium_104 VEHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHGVPAGRRRTML
::* * **. *::* :* **. .*** ** :*: .* . . * ::
Mb3106c|M.bovis_AF2122/97 DERLRAIIEIWTQEQAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGGGP-A
Rv3079c|M.tuberculosis_H37Rv DERLRAIIEIWTQEQAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGGGP-A
Mflv_1017|M.gilvum_PYR-GCK DERIEAIKVLWTQEPAEYHGRFVDFDASYQRPKPVRKPHPPILIGGDSDA
Mvan_5819|M.vanbaalenii_PYR-1 DERIEAIKALWTAEPAEYHGKYVDFDASYLRPKPVQKPHPPILIGGDSDA
TH_2750|M.thermoresistible__bu DERIEAVKALWTDEPAEYHGRFVDFGPSYLRPKPVQKPHPPIVVGGNSDA
MMAR_3559|M.marinum_M DERIEAIKALWTDEPAEYHGKYVDFPPSYSRPKPVRQPHPPIYIGGNSDA
MUL_2792|M.ulcerans_Agy99 DERIEAIKALWTDEPAEYHGKYVDFPPSYSRPKPVRQPHPPIYIGGNSDA
MSMEG_1996|M.smegmatis_MC2_155 DEQIEAIKALWTQEPAEYHGKYVDIESSYMRPKPVQKPHPPIYIGGASEA
MAB_1059c|M.abscessus_ATCC_199 REYIEAMRRLWEEEEASYSGEFVNFGPSWAWPKTVQKHVPVIVGAGGTEK
MAV_1077|M.avium_104 REYLEAMRALWTQEEAAYDGEFVKFGPSWAWPKPVQPHIPVLVGAAGNEK
* :.*: :* * * : * :*.: . : **.* * : ..
Mb3106c|M.bovis_AF2122/97 NFPRIARLNAGWIAISPS--PQRLSGPLQRLRAMAGGD-VPVTVCQWGEA
Rv3079c|M.tuberculosis_H37Rv NFPRIARLNAGWIAISPS--PQRLSGPLQRLRAMAGGD-VPVTVCQWGEA
Mflv_1017|M.gilvum_PYR-GCK TVRRIIRHGAGWIANPLP--IDHLSRRIEQIREGAGGD-VPLCQFGT-PV
Mvan_5819|M.vanbaalenii_PYR-1 AVKRIIRHEAGWISNPLP--VDTLRRRVDQIRAGARHE-VPLSMFGT-PV
TH_2750|M.thermoresistible__bu TVRRIIRHGAGWMSNPHP--PEMLKRRVQQIRDGAGHD-VLLTTFGT-PV
MMAR_3559|M.marinum_M TVKRVVRHDAGWISNPLP--VRQLTQRVDQLRGAAGHD-VPLAMFGT-PN
MUL_2792|M.ulcerans_Agy99 TVKRVVRHDAGWISNPLP--VHQLTQRVDQLRSAAGHD-VPLAMFGT-RN
MSMEG_1996|M.smegmatis_MC2_155 TVKRVIRHDAGWISNPLP--VDFLSKFVTQMRDGLGHE-VPLAQFGT-PA
MAB_1059c|M.abscessus_ATCC_199 NFTWIAKNADGWMSTPRDEDIAGKIVALKEAWKAAGRDGDPLIYVLAGKP
MAV_1077|M.avium_104 NFKWIARSADGWITTPRDFDIDEPVKLLQDTWAAAGRDGAPQIVALDFKP
. : : **:: . : :
Mb3106c|M.bovis_AF2122/97 AAKDLEGYRHLGVE---RVLLELPTE-----------PRD--------PT
Rv3079c|M.tuberculosis_H37Rv AAKDLEGYRHLGVE---RVLLELPTE-----------PRD--------PT
Mflv_1017|M.gilvum_PYR-GCK KPEYWQAAEELGFG---QLNLLLPTK-----------SRD--------VS
Mvan_5819|M.vanbaalenii_PYR-1 KPEYWQAAEDLGFG---QLNLLLPTK-----------PRD--------ES
TH_2750|M.thermoresistible__bu DPGYWEVLEELGYQ---QANLLLPTR-----------PRD--------ES
MMAR_3559|M.marinum_M KPDYWRAAQDLGFG---QLALLLPT-----------CPRD--------ES
MUL_2792|M.ulcerans_Agy99 KPDYWRAAQDLGFGPAGAAAAHLPAGGVPAAARRIRCPGGSIPPVEVPGG
MSMEG_1996|M.smegmatis_MC2_155 DPEYWGAVEELGFG---QIALLLPT-----------LPTD--------ES
MAB_1059c|M.abscessus_ATCC_199 DPEQLAAWRELGVT---EAIFGMPDR-----------SEE--------EV
MAV_1077|M.avium_104 DAEKLARWAELGVT---EVLFGLPDK-----------SED--------EV
. .** :* .
Mb3106c|M.bovis_AF2122/97 LRYLDKLQAELARLA-----------------------------
Rv3079c|M.tuberculosis_H37Rv LRYLDKLQAELARLA-----------------------------
Mflv_1017|M.gilvum_PYR-GCK LRLLDDYAEQVARYIG----------------------------
Mvan_5819|M.vanbaalenii_PYR-1 LRLLDGYAEQVARY------------------------------
TH_2750|M.thermoresistible__bu LRMLDQFAERVAGYRG----------------------------
MMAR_3559|M.marinum_M LRLLDEYAALVAQYHR----------------------------
MUL_2792|M.ulcerans_Agy99 PSFLREPLARVSCASRRKIAPRFAAQCDFASARGGRLRVGSRPR
MSMEG_1996|M.smegmatis_MC2_155 LRMLDDYATAVEKYRG----------------------------
MAB_1059c|M.abscessus_ATCC_199 RAYIDRLSGKLAAFA-----------------------------
MAV_1077|M.avium_104 AAYVERLAGKLAALV-----------------------------
: :