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LSRCARWALEAPRRVVVCIALLTVAAGIIGFPVVSHLSAGGFADPGAESSQANRVLSEKFGKGDVQLILV VSGGEGDGEATAAEGRRIVDLLAGSPNVLGVLSPWTSPPEMAAGLRSADGRADLIVADLRGGESDGPGYA RELVERIDADLAAGGSSVSVTPGGSAMVFDQITTQTLRDVLIMESIAVPLSLAVLVWVFGGLLVAALPVL VAVVAIVATMAVLRLIAMGTDVSIFALNLASALGLALAIDYTLLIVSRFRDEMALDHDRSRALRTTMATA GRTIVFSALTVALSMSTLVLFDVPFLRSFGYAGVATVVLCAVAALVFSPALMVLLGDRLMRRPGRHRADG DGRDAVHHRFWFRSTQFVLRHALPVGLAGSALLVCAGLPFLGVKWGYPDDRVLPASASAHQVGDQLREQF VGLSGTETTVVAPDATGISDADWERYAADLSRVPDVTAVAAPAGTFVDGRPAGPAAVGAEIADGSAYLTV TGSAALFSAESEDQLADLKAVPGPGGRDVVMTGAAAVNRDSIHSIAEKLPTVLGLTAAVIFVVLFALTRS VVLPLKALVLNGLSLTAAFGALVWIFQDGHLGAFGTTPTGTLVATIPVLLFCIAFGLSMDYEVFLLARIR EFWLRSGRSAADLDRSVVLGLAYTGRVVTAAALIMTLSFAGLIAAQVSFMRMFGVGLVLAVLVDATLVRM VLLPAYMKLLGRFNWWAPRLPTRAVVRERV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0467 | - | - | 100% (731) | MMPL domain-containing protein |
| M. gilvum PYR-GCK | Mflv_2131 | - | 0.0 | 58.41% (743) | MMPL domain-containing protein |
| M. gilvum PYR-GCK | Mflv_5139 | - | 0.0 | 59.25% (719) | MMPL domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1177 | mmpL13 | 0.0 | 57.30% (740) | transmembrane transport protein MmpL13 |
| M. tuberculosis H37Rv | Rv1146 | mmpL13b | 1e-134 | 61.18% (425) | transmembrane transport protein MmpL13B |
| M. leprae Br4923 | MLBr_02620 | - | 7e-78 | 28.95% (746) | hypothetical protein MLBr_02620 |
| M. abscessus ATCC 19977 | MAB_1287 | - | 0.0 | 51.71% (731) | MmpL family membrane protein |
| M. marinum M | MMAR_4305 | mmpL13 | 0.0 | 57.47% (743) | transmembrane transport protein MmpL13 |
| M. avium 104 | MAV_1287 | - | 0.0 | 57.39% (737) | mmpL protein |
| M. smegmatis MC2 155 | MSMEG_5178 | - | 0.0 | 58.63% (730) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1538 | - | 0.0 | 54.52% (730) | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B |
| M. ulcerans Agy99 | MUL_0989 | mmpL13 | 0.0 | 57.20% (743) | transmembrane transport protein MmpL13 |
| M. vanbaalenii PYR-1 | Mvan_1577 | - | 0.0 | 62.71% (724) | polyprenyl synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0467|M.gilvum_PYR-GCK -----------------------MLSRCARWALEAPRRVVVCIALLTVAA
Mvan_1577|M.vanbaalenii_PYR-1 MPSGTTLSSEPALRPAVMEKRRRLLHRIALCAIAAPRRIVAIAALVMVGA
Mb1177|M.bovis_AF2122/97 -----------------------MLQRIARLAIAAPRRIIGFAVFVFIAA
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 -----------------------MLQKIARVAIAAPRRIIALGVLVFLAA
MMAR_4305|M.marinum_M -----------------------MLQGIARLAIAAPRRIIGVALLVFIAA
MUL_0989|M.ulcerans_Agy99 -----------------------MLQGIARLAIAAPRRIIGVALLVFIAA
MSMEG_5178|M.smegmatis_MC2_155 -----------------------MLQRIATTAIAAPRRILVVAALVMIAA
TH_1538|M.thermoresistible__bu -----------------------MLETLARRIVAAPRRVLALVVLVIVGA
MAB_1287|M.abscessus_ATCC_1997 ----------------------MMLERLARSVIAAPRLVLGMALLIAIAA
MLBr_02620|M.leprae_Br4923 -----------------------MFAWWGRTVYRYRFIVIGITVALCLCG
Mflv_0467|M.gilvum_PYR-GCK GIIGFPVVSHLSAGGFADPGAESSQANRVLSEKFGKGDVQLILVVSGGE-
Mvan_1577|M.vanbaalenii_PYR-1 AIFGVPVAGSLAAGGFQDPGSESARATRVLTETFGRGDMQLVFAVTDPA-
Mb1177|M.bovis_AF2122/97 AVFGVPVADSLSPGGFQDPRSESARAIEVLTDKFGQSGQKMLIVVTAAA-
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 AVFGIPVAKSLSPGGFQDPDSESARAIGVLTDKFGQSGQQMLILVTAPG-
MMAR_4305|M.marinum_M AVFGIPVANSLSPGGFQDPNAESARAIKVLADKFGQSGQQMLILVTAPG-
MUL_0989|M.ulcerans_Agy99 AVFGIPVANSLSRGGFQDPNAESARAIKVLADKFGQSGQQMLILVTAPG-
MSMEG_5178|M.smegmatis_MC2_155 GIFGIPVANKLSAGGFQDPTAESARATQLLADKFHRGDMQLVIAVTAEAP
TH_1538|M.thermoresistible__bu AMFGLPVAGSLSAGGFRDPHSESAQASALLAERFDQTDMQLLVTVSSSA-
MAB_1287|M.abscessus_ATCC_1997 ALFGVPVTKHLAAGGQQDPNSESAYVTKALRDKFDISDQSLVFMLTSEQ-
MLBr_02620|M.leprae_Br4923 GVFGLSLGKHVTQSGFYDDSSQSVKASILGDQVYGRDRSGHIVAIFHAPD
Mflv_0467|M.gilvum_PYR-GCK --GDGEATA-AEGRRIVDLLA--GSPNVLGVLSPWTSP---PEMAAGLRS
Mvan_1577|M.vanbaalenii_PYR-1 --GVDSASARAAGLAIATLVG--EDPAVADVVSTWTVA---PEAAAALIS
Mb1177|M.bovis_AF2122/97 --GADSPPAREVGTDIVEVLR--RSPLVYNVTSPWTVP---PTAAADLLS
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --GSNSDPARRVGTELVEQLQ--RSPLVYNVSSPWTAP---PQASADLVS
MMAR_4305|M.marinum_M --GVGTERARAVGTDIVAELN--HSPLVFNVSSPWTGPSADPKSAPDLVS
MUL_0989|M.ulcerans_Agy99 --GVGTERARAVGTDIVAELN--HSPLVFNVSSPWTGPSADPKSAPDLVS
MSMEG_5178|M.smegmatis_MC2_155 GGRADGGRAREVGTEIVSELK--ASPYVTEVTSAWTAP---PSAAAALVS
TH_1538|M.thermoresistible__bu --GVYGEAARRVGTEIVAALE--ASPQVAGVQSPWTVP---PGAGDRLVS
MAB_1287|M.abscessus_ATCC_1997 --GVKSPQMRAVAADLERQLK--DSGVVINLTSAWTAP---PQVAEELLG
MLBr_02620|M.leprae_Br4923 GKTVNDPAWAKKITDELNQFQRNNSNKVTGWAGYLRASDTTNTVVQGMAT
Mflv_0467|M.gilvum_PYR-GCK ADGRADLIVADLRGGESDGPGYARELVERIDADLAAGGSSVSVTPGGSAM
Mvan_1577|M.vanbaalenii_PYR-1 ADGRSGLVVAELTGDENTAPRIAQALVDEVATTVQPRHETVAVLAGGSSI
Mb1177|M.bovis_AF2122/97 TDGKSGLIVVNVKGGENDAQNHAQTLSDEVAHDRDG----VTVRAGGSAM
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 RDGKSGLIVVNLKGGENFVQNNAQTLADQFVHDRDG----VTVRAGGAAM
MMAR_4305|M.marinum_M KDGKSGLIVVNIKGGESNAQKNAQTLADEIVHDRDG----VTVRAGGSAM
MUL_0989|M.ulcerans_Agy99 KDGKSGLIVVNIKGGESNAQKNAQTLADEIVHDRDG----VTVRAGGSAM
MSMEG_5178|M.smegmatis_MC2_155 KDARTGLIVAGLNGGENGAQQHAKELTDQFVRDHDG----VRVRAGGEAM
TH_1538|M.thermoresistible__bu EDATAGLIVAPIRGNETESSDIARQLAAAVGSDRDR----VNVRAGGPAL
MAB_1287|M.abscessus_ATCC_1997 ADGKAGLIVAGLTGGENDAQKHAAKLIKSLAVDRDG----VAVKAGGVAT
MLBr_02620|M.leprae_Br4923 PDKKYTFVSIPLKGDDDDTILNNYKAIAPDLQKLDG----GTVQLAGLDP
Mflv_0467|M.gilvum_PYR-GCK VFDQITTQTLRDVLIMESIAVPLSLAVLVWVFGGLLVAALPVLVAVVAIV
Mvan_1577|M.vanbaalenii_PYR-1 VYSQINSQTLRDVLLMEAIAIPLTFLVLVWVFKGLLAAALPVAVGGLAIV
Mb1177|M.bovis_AF2122/97 EYAQINRQNKDDLLVMELIAIPLSFLVLIWVFGGLLAAGLPMAQAVLAVV
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 QYAQINTQNQADLLVMEMIALPLSFLVLIWVFGGLLAAALPMALGALAVV
MMAR_4305|M.marinum_M EYAQINKQNQDDLLVMELIAIPLSFLVLVWVFGGLLAAALPMALGALAVV
MUL_0989|M.ulcerans_Agy99 EYAQINKQNQDDLLVMELIAIPLSFLVLVWVFGGLLAAALPMALGALAVV
MSMEG_5178|M.smegmatis_MC2_155 IYVQINGQSEKDLLMMESIAIPLSFVVLVWVFGGLLAAALPLAVGGFAIL
TH_1538|M.thermoresistible__bu VNAQIDTQTEHDLLVMEAIAIPLSFVVLVWVFGGLLAAALPLAVGVLAIV
MAB_1287|M.abscessus_ATCC_1997 LYNQIVTQSEKDLLVMESIAIPISFVVLVWIFGGLYAALLPLVVGVFSIV
MLBr_02620|M.leprae_Br4923 IANALTSTIATDQRRMEVLALPLVAVVLFLVFGGVIAACLPVMVGGLSIA
Mflv_0467|M.gilvum_PYR-GCK ATMAVLRLIAMGTDVSIFALNLASALGLALAIDYTLLIVSRFRDEMALDH
Mvan_1577|M.vanbaalenii_PYR-1 ASMSVLRLVAMWTDVSIFALNLTTALGLALAVDYTLLIVSRFRDEVAAGA
Mb1177|M.bovis_AF2122/97 GSMAVLRLVTFATEVSTFALNLSTALGLALAIDYTLLIVSRYRDELAEGS
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 GSMSVLRLITFTTEVSIFALNLSTALGLALAIDYTLLIVSRYRDELAEGH
MMAR_4305|M.marinum_M GSMSVLRLVTFTTDVSIFALNLSTALGLALAIDYTLLIISRYRDELAEGS
MUL_0989|M.ulcerans_Agy99 GSMSVLRLVTFTTDVSIFALNLSTALGLALAIDYTLLIISRYRDELAEGS
MSMEG_5178|M.smegmatis_MC2_155 GSLAVLRLFTMVTDVSIFALNLTVAMGLALAIDYTLLIISRFRDELAEGA
TH_1538|M.thermoresistible__bu GSMAVLRTFTMFTEVSVFALNLSIAMGLALAIDYTLLLLNRYRDELAEGC
MAB_1287|M.abscessus_ATCC_1997 GAMSILRGLTYVTDVSVFALNLAVAMGLALAIDYSLLIISRYREEVNAGK
MLBr_02620|M.leprae_Br4923 GALGILRFIALFGPVHFFAQPVVSLIGLGIAVDYGLFVVSRFREEIAEGY
Mflv_0467|M.gilvum_PYR-GCK DRSRALRTTMATAGRTIVFSALTVALSMSTLVLFDVPFLRSFGYAGVATV
Mvan_1577|M.vanbaalenii_PYR-1 PRDRALVTTMVTAGRTVLFSALTVALSMAAMLLFPMYFLKSFAYAGLATV
Mb1177|M.bovis_AF2122/97 DRDEALIRTMATSGRTVLFSAVTVALSMSATALFPMYFLKSFAYAGVATV
Rv1146|M.tuberculosis_H37Rv ----------------------------------------------MATV
MAV_1287|M.avium_104 DRDQALIRTMATSGRTVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATV
MMAR_4305|M.marinum_M SREEALVRTMATSGRTVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATV
MUL_0989|M.ulcerans_Agy99 SREEALVRTMATSGRTVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATV
MSMEG_5178|M.smegmatis_MC2_155 DRETALVRTMMTAGRTVLFSAMTVALSMVAMVLFPMYFLKSFAYAGIAVV
TH_1538|M.thermoresistible__bu SREQAVIRTMTSAGRTVIFSAVIVATSMVPLALFPMYFLRSFAYAGVGVV
MAB_1287|M.abscessus_ATCC_1997 PRDEALVLTMTTAGRTVLFSALTVALALVALILFPMYFLKSFGYAGVAVV
MLBr_02620|M.leprae_Br4923 DTEAAVRRTVMTAGRTVTFSAVLIAASGASLLLLPQGFVKSLTYALIAAV
:..*
Mflv_0467|M.gilvum_PYR-GCK VLCAVAALVFSPALMVLLGDRLMRRPGR--HRADG---------------
Mvan_1577|M.vanbaalenii_PYR-1 ALCAVAAIVVTPAVIALFGDRLDAFDIRRMLRRTP---------------
Mb1177|M.bovis_AF2122/97 AFVATASIVITPAAIVLLGPRLDALDVRRLVRRLL---------------
Rv1146|M.tuberculosis_H37Rv AFVATASIVITPAAIVLLGPRLDALDVRRLVRRLL---------------
MAV_1287|M.avium_104 AFVATASIVITPAAIVLLGDRLDALDVRRLLRRAL---------------
MMAR_4305|M.marinum_M AFVATASIVVTPAAIVLLGPRLDALNVRRLARRML---------------
MUL_0989|M.ulcerans_Agy99 AFVATASIVVTPAAIVLLGPRLDALNVRRLARRML---------------
MSMEG_5178|M.smegmatis_MC2_155 ALAATAAIVLTPAAIVLLGDRLDAYDVRRFFRRVF---------------
TH_1538|M.thermoresistible__bu AFALCAALVITPAAITVLGARLDSWDIRRLIRRLMRR-------------
MAB_1287|M.abscessus_ATCC_1997 FVGAIAALVIVPAVVTLLGDRIDALDVRRLIRRVL---------------
MLBr_02620|M.leprae_Br4923 TLAALLSITLLPACLAILAKHVDALGVRTLFRVPLLRNWRMSHACLNWLA
. ::.. ** :.::. :: * *
Mflv_0467|M.gilvum_PYR-GCK --DGRDA----VHHRFWFRSTQFVLRHALPVGLAGSALLVCAGLPFLGVK
Mvan_1577|M.vanbaalenii_PYR-1 --AAEPR----GEQMFWYRSTKFVMRRALPVGLAGTALLVSLGLPFLGVS
Mb1177|M.bovis_AF2122/97 --GRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALLVLLGLPFLSVK
Rv1146|M.tuberculosis_H37Rv --GRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALLVLLGLPFLSVK
MAV_1287|M.avium_104 --RRAQPVRKPVEQLFWYRSSKFVMRRWAPVGLIVVGLLLLLGLPFFSVK
MMAR_4305|M.marinum_M --GRPEPQHKPVDQLFWYRSTKFVMRRALPVGLAVVAVLVILGLPFFSVK
MUL_0989|M.ulcerans_Agy99 --GRPKPQHKPVDQLFWYRSTKFVMRRALPVGLAVVAVLVILGLPFFSVK
MSMEG_5178|M.smegmatis_MC2_155 --GRPEPEPKPVEQGFWYRTAKAAMRRAVPIGVGIIALLVLLGVPFTGIK
TH_1538|M.thermoresistible__bu TPAAAEPAPRAVCGSKWYRWAKAVMRHWLVAGLAVTVVLLLLGAPFLGVR
MAB_1287|M.abscessus_ATCC_1997 --GRPEPVAKDVTQSFWYRTTKRVMARAVPIAIIIVSALVVLGLPFLDGK
MLBr_02620|M.leprae_Br4923 DRLQKTKTREEVEAGFWGKLVNFVMKRPLVFAIPIVIGMILLVIPLGNLS
* : : .: : . :: *: .
Mflv_0467|M.gilvum_PYR-GCK WGYPDDRVLPASASAHQVGDQLREQFVGLSGTETTVVAPDATGISDADWE
Mvan_1577|M.vanbaalenii_PYR-1 WGLPDDRVLPSSATAHRVGDMLRTEFSDNSEAAVTVLVPDAEGLTPQDFE
Mb1177|M.bovis_AF2122/97 WGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELD
Rv1146|M.tuberculosis_H37Rv WGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELD
MAV_1287|M.avium_104 WGFPDDRVLPRSASAHQVGDRLRSGFAHDSATSVPVVIPDAAGLSPADLD
MMAR_4305|M.marinum_M WGFPDDRVLPATASSHQVGDELRTNFAHDLAMAVPVVVPDVRGLVPADLD
MUL_0989|M.ulcerans_Agy99 WGFPDDRVLPATASSHQVGDELRTNFAHDLAMAVPVVVPDVHGLVPADLD
MSMEG_5178|M.smegmatis_MC2_155 WGFPDDRVLPQSASARQIGDEMRTNFAVDSATSVTVVLPDATTVAPAEID
TH_1538|M.thermoresistible__bu WGFPDERVLPRSASAHQVGHELRTNFATDSASDVTVVLPDAPGLTADELA
MAB_1287|M.abscessus_ATCC_1997 FGFPDDRVLPASASAHQVGNEMRRNFNNNSSTNLSVIAEGVGSVPPREID
MLBr_02620|M.leprae_Br4923 FGGMSEKYLPPNNAVRQSQEHFDQLFPGYRTNPLTLVIQTSN-HQPVTDQ
:* .:: ** . : :: . : * .::
Mflv_0467|M.gilvum_PYR-GCK RYAADLSRVPDVTAVAAPAGTFVDGRPAGPAAVGAEIADGSAYLTVTGSA
Mvan_1577|M.vanbaalenii_PYR-1 RYAAEASTIEDVSMVSAPTGTFADGRRVGPPAGGAGVQGGIAYLTVGSTT
Mb1177|M.bovis_AF2122/97 SYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTA
Rv1146|M.tuberculosis_H37Rv SYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTA
MAV_1287|M.avium_104 DYAAALSRVPDVSAVSAPGGTFTGGTRVGPPAGATGLGDGSAFLTVSSTA
MMAR_4305|M.marinum_M GYAADLSRVPDVASVTAPSGTFVNGSRVGPPAGATGFSDGSAFLTVDSTA
MUL_0989|M.ulcerans_Agy99 GYAADLSRVPDVASVTAPSGTFVNGSRVGPPAGATGFSDGSAFLTVDSTA
MSMEG_5178|M.smegmatis_MC2_155 RYAARLSQVADVSSVSAPGGTDVQGRHVGPPSAATGIGDGSAFLTVGSDA
TH_1538|M.thermoresistible__bu GYAARLSEVTDVAWVSAPAGTFVRGRSVGPPSAPTGIADGSAFVTVGSVA
MAB_1287|M.abscessus_ATCC_1997 EYAADLSNIEDVKEVAAPTGAFIRGMKVGPSASATGIKNDTALFTVQTAA
MLBr_02620|M.leprae_Br4923 EIADIRSKAMAISGFIEPDNNYVNMWQERTVAPGASKDPS---VRVLQNG
* * : . * . . : . . *
Mflv_0467|M.gilvum_PYR-GCK ALFSAESEDQLADLKAVPGPGGRDVVMTGAAAVNRDSIHSIAEKLPTVLG
Mvan_1577|M.vanbaalenii_PYR-1 ASFSPESERQLDRLRALPGPGGRPVQMTGIAQINRDSVESIMARLPIVLG
Mb1177|M.bovis_AF2122/97 PLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLG
Rv1146|M.tuberculosis_H37Rv PLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLG
MAV_1287|M.avium_104 PLFSTANDVQLKRLHEVPGPAGRSVEMGGVAQVNRDSVDAVTDRLPLVLG
MMAR_4305|M.marinum_M PLFSHASDIQLKRLHQVTGPAGRTVEMAGVAQVNRDSVDAVTERLPLVLG
MUL_0989|M.ulcerans_Agy99 PLFSHASDIQLKRLHQVTGPAGRTVEMAGVAQVNRDSVDAVTERLPLVLG
MSMEG_5178|M.smegmatis_MC2_155 PLFSDASEAQLDALHAVAAHA--EVQFTGVAQVNRDSSQAITSRLPLVLG
TH_1538|M.thermoresistible__bu PLFSDDSLEQLNDIRAVPAPGGTAVQLTGTAQINHDIVVAVTSRLTVVLT
MAB_1287|M.abscessus_ATCC_1997 KPYTEAAERQLDAIHALPGPADVLVRIGGGAQLDRDAVDGIVHKLPLVLA
MLBr_02620|M.leprae_Br4923 LINPNDASKKINELRSITPPKGLTVSVGGTPALEQDSIHSLVAQAPLMVI
. :: :: :. * . * . :::* .: : . ::
Mflv_0467|M.gilvum_PYR-GCK LTAAVIFVVLFALTRSVVLPLKALVLNGLSLTAAFGALVWIFQDGHLGAF
Mvan_1577|M.vanbaalenii_PYR-1 IIAVITFVLLFLLTGSLVLPVKALVLNALSLTAAFGALVWIFQDGNLGAL
Mb1177|M.bovis_AF2122/97 LIAAITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGAL
Rv1146|M.tuberculosis_H37Rv LIAAITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGAL
MAV_1287|M.avium_104 LMAAITFVLLFLLTGSVLLPAKALACNFLSLTAAFGALVWIFQDGHLGAL
MMAR_4305|M.marinum_M LMAAITFVLLFLLTGSVVLPAKALICNVLSLTAAFGALVWIFQDGHLGAL
MUL_0989|M.ulcerans_Agy99 LMAAITFVLLFLLTGSVVLPAKALICNVLSLTAAFGALVWIFQDGHLGAL
MSMEG_5178|M.smegmatis_MC2_155 IIAGITFVLLFLLTGSVVLPLKALVLNVLSLSAAFGALVWIFQDGHLGAL
TH_1538|M.thermoresistible__bu VIALTTLVWLFLLTGSIVLPIKALVLNALSLTAAFGALVWIFQDGHLGAL
MAB_1287|M.abscessus_ATCC_1997 IIAVVTFVLLFLLTGSVVLPIKALVLNVLSLTATFGALIWIFQEGHLGGF
MLBr_02620|M.leprae_Br4923 MLITTTMLLMFLAFGSFVLPIKAAVMSALTLGSTMGILTWIFVDGHLSKW
: : :* *.:** ** . *:* :::* * *** :*::.
Mflv_0467|M.gilvum_PYR-GCK GTTPTGTLVATIPVLLFCIAFGLSMDYEVFLLARIREFWLRSGRSA----
Mvan_1577|M.vanbaalenii_PYR-1 GTTPTGTLVVNMPVLLFCIAFGLSMDYEVFLLARIREFWLAGGR------
Mb1177|M.bovis_AF2122/97 GTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARR
Rv1146|M.tuberculosis_H37Rv GTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARR
MAV_1287|M.avium_104 GTTPSGTLVANMPVLLFCIAFGLSMDYEVFLLSRIREYWLASGAARPARP
MMAR_4305|M.marinum_M GTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVARIREYWLASGAARPATP
MUL_0989|M.ulcerans_Agy99 GTIPSGTLVANMPVLLFCIAFGLSMDYEVFLVARIREYWLASGAAGPATP
MSMEG_5178|M.smegmatis_MC2_155 GTTPTGTLVANLPVLLFCIAFGLSMDYEVFLVSRIREFWLQSDQSR----
TH_1538|M.thermoresistible__bu GTTPSGTMAVTMPALLLCVAFGISMDYEVFLIARIREHWLASSRTA----
MAB_1287|M.abscessus_ATCC_1997 GTEVTGTIVATMPMLLFCIAFGLSMDYEVFLISRIREYWMASGRTR----
MLBr_02620|M.leprae_Br4923 LNFTPTPLMVVIIALVVAVGYGLATDYEVFLVSRMVEARAESMSTQ----
. . .: . : *:..:.:*:: ******::*: * .
Mflv_0467|M.gilvum_PYR-GCK ------ADLDRSVVLGLAYTGRVVTAAALIMTLSFAGLIAAQVSFMRMFG
Mvan_1577|M.vanbaalenii_PYR-1 ------RDNDESVALGLAHTGRVVTAAALIMSISFGALIAAQVSFMRMFG
Mb1177|M.bovis_AF2122/97 SVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFG
Rv1146|M.tuberculosis_H37Rv SVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFG
MAV_1287|M.avium_104 TPKRAHAANDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFG
MMAR_4305|M.marinum_M SPAQAHAANDESVALGLARTGRVITAAALVMSMSFAALIAAHVSFMRMFG
MUL_0989|M.ulcerans_Agy99 SPAQAHAANDESVALGLARTGRVITAAALVMSMSFAALIAAHVSFMRMFG
MSMEG_5178|M.smegmatis_MC2_155 ------AANEESVALGLAHTGRVITAAALLMSISFAALIAAQVAFMRMFG
TH_1538|M.thermoresistible__bu ------AANDEAVALGVARTARVITAAALIMSISFAALIGAQVSFMRMIG
MAB_1287|M.abscessus_ATCC_1997 ------ADNDEAVALGVARTGRVVTAAALIMAIAFAALMAAQVSFMRMFG
MLBr_02620|M.leprae_Br4923 ----------EAVRIGTASTGRLITAAALVLAVVAGSFVFSDLVMMKYLA
.:* :* * *.*::*****:::: ..:: :.: :*: :.
Mflv_0467|M.gilvum_PYR-GCK VGLVLAVLVDATLVRMVLLPAYMKLLGRFNWWAP----------------
Mvan_1577|M.vanbaalenii_PYR-1 LGLMLAVLIDATLVRMVLLPAFMHLMGRWNWWAPAPLARWHARRTGTAEQ
Mb1177|M.bovis_AF2122/97 LGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFG-----
Rv1146|M.tuberculosis_H37Rv LGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFG-----
MAV_1287|M.avium_104 LGLTLAVFADATLVRMVVVPAFMHVMGRWNWWAPKPLAWLHDRFG-----
MMAR_4305|M.marinum_M LGLTLAVAADATLVRMVLVPAFMHVMGRWNWWAPKPLVWLHQRFG-----
MUL_0989|M.ulcerans_Agy99 LGLTLAMAADATLVRMVLVPAFMHVMGRWNWWAPKPLVWLHQRFG-----
MSMEG_5178|M.smegmatis_MC2_155 LGLTLAVLVDATLVRMLLVPAFMRVMGRWNWWAPAPLARLHERIG-----
TH_1538|M.thermoresistible__bu LGLMVAVLVDATLVRLILVPAFMHVMGRANWWAPAPLARWHDRFG-----
MAB_1287|M.abscessus_ATCC_1997 TGLTIAILVDATIIRMLLVPSFMRLLGRFNWWAPKPLVTLHERIG-----
MLBr_02620|M.leprae_Br4923 FGLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARLLQNRIG-----
** *: ***::*:.::*: *:: * ****
Mflv_0467|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 NANPTKSGAAIASNGRRRPRHGWVERGGGPQLSRGDGAGAQLAEPGLMAW
Mb1177|M.bovis_AF2122/97 -----------------------------------------------VSE
Rv1146|M.tuberculosis_H37Rv -----------------------------------------------VSE
MAV_1287|M.avium_104 -----------------------------------------------ISE
MMAR_4305|M.marinum_M -----------------------------------------------ISE
MUL_0989|M.ulcerans_Agy99 -----------------------------------------------ISE
MSMEG_5178|M.smegmatis_MC2_155 -----------------------------------------------FSE
TH_1538|M.thermoresistible__bu -----------------------------------------------IRE
MAB_1287|M.abscessus_ATCC_1997 -----------------------------------------------FSD
MLBr_02620|M.leprae_Br4923 --------------------------------------LGEIHLPDERRR
Mflv_0467|M.gilvum_PYR-GCK RLPTRAVVRERV--------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 RDTVRTAVREHLEDFVRGECARRLDGGGVDVAAELLCGFLDGGKYVRSTY
Mb1177|M.bovis_AF2122/97 AAEPVSRRRSHAGG--LGKIAGRSDGQT------------IPAS------
Rv1146|M.tuberculosis_H37Rv AAEPVSRRRSHAGG--LGKIAGRSDGQT------------IPAS------
MAV_1287|M.avium_104 AADEEPRLRACPRTRRIRRIARRRGRRTGAQHRLTAV---RPTARRVWRS
MMAR_4305|M.marinum_M TGAVGDADAAATEA------ADRRDRPT------------IPAA------
MUL_0989|M.ulcerans_Agy99 TGAVGGADAAATEA------ADRRDRPT------------IPAA------
MSMEG_5178|M.smegmatis_MC2_155 SGLPPDPKPQPASVG-----------------------------------
TH_1538|M.thermoresistible__bu AADAPDRPRSDPAPTPXXXDASVRKGPAPSS---------ISRDPAVPAY
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 PTVSGRPVRPPVTAASLAAPASRVPRGPTHPATLEPSQRARSGLASRPQI
Mflv_0467|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 MYLGWLCGEREDTAALRASASLELLHTFALIQDDVMDSSPMRRARPSAHV
Mb1177|M.bovis_AF2122/97 -----LTRNG----------------------------------------
Rv1146|M.tuberculosis_H37Rv -----LTRNG----------------------------------------
MAV_1287|M.avium_104 DPILRLIRGGRCTQA-----------------------------------
MMAR_4305|M.marinum_M -----LSGRG----------------------------------------
MUL_0989|M.ulcerans_Agy99 -----LSGRG----------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 -----MTQSG----------------------------------------
TH_1538|M.thermoresistible__bu VPDRPRTRSACRCSR-----------------------------------
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 KRPQELPSGASTARIQMRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQA
Mflv_0467|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 ALGRWHRDRALSGSASRFGESAAILLGDLCLVWAEEMLRRSGVDADALAR
Mb1177|M.bovis_AF2122/97 --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --------------------------------------------------
MMAR_4305|M.marinum_M --------------------------------------------------
MUL_0989|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------------------
TH_1538|M.thermoresistible__bu --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 VPLAATRHPLPTPSPASGQTRAMPVPANRSSDNASETAEPTTALPIMRPQ
Mflv_0467|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 VWPRYDAMRTELAIGQLSDLLNSCQTFPTLPEVLDVLRRKSGNYTVRRPL
Mb1177|M.bovis_AF2122/97 --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --------------------------------------------------
MMAR_4305|M.marinum_M --------------------------------------------------
MUL_0989|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------------------
TH_1538|M.thermoresistible__bu --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 DNDSEVATEKLNALGQGDNSRQHRRATGGGISAQDLLRREGRL-------
Mflv_0467|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 ELGAAMAGCSADVADALSGYGAAIGEAFQLRDDILGVFGSPSLTGKSVRS
Mb1177|M.bovis_AF2122/97 --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --------------------------------------------------
MMAR_4305|M.marinum_M --------------------------------------------------
MUL_0989|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------------------
TH_1538|M.thermoresistible__bu --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 --------------------------------------------------
Mflv_0467|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 DLEDGKATSIVVAAYELAGPRLRRQLAELMQSPEIGAADVDRWRTLIRAS
Mb1177|M.bovis_AF2122/97 --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --------------------------------------------------
MMAR_4305|M.marinum_M --------------------------------------------------
MUL_0989|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------------------
TH_1538|M.thermoresistible__bu --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 --------------------------------------------------
Mflv_0467|M.gilvum_PYR-GCK ----------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 GAVQWIEEQIARRHDAALRFLDGAAIPAAPRAALAEMAVACTQRAA
Mb1177|M.bovis_AF2122/97 ----------------------------------------------
Rv1146|M.tuberculosis_H37Rv ----------------------------------------------
MAV_1287|M.avium_104 ----------------------------------------------
MMAR_4305|M.marinum_M ----------------------------------------------
MUL_0989|M.ulcerans_Agy99 ----------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 ----------------------------------------------
TH_1538|M.thermoresistible__bu ----------------------------------------------
MAB_1287|M.abscessus_ATCC_1997 ----------------------------------------------
MLBr_02620|M.leprae_Br4923 ----------------------------------------------