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SPVRVPVAVLARAQAALGDLRADAEVLIGGRAALLGLAPDGRISAGGATRLLAGPDGWCALTLSRPDDVD AVPALLGADDLPDDMWSAIGRVIAETGVWVFAERARLLGLPVGVLGEATEAPTALCRNGERKAFGDLNGL LVADLSSMWAGPLCGRLLSDAGATVVKVETRTRPDGTRQGSAAFFDWMNSGKLAYAADLEDPGLRRLLGA ADVVIESSRPAALQRRGLGPTDVAGPAGRVWVRITGHGTDGARADWVAFGDDAAVSGGLVSGSPADPRFC GDAIADPLTGIRAAAEVLASRRRGGGELIELSMAGVAAEYAQLPRGDEKPCVATPVAAPRGPALGADNAA VDRLVADRATLPC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0444 | - | - | 100% (364) | hypothetical protein Mflv_0444 |
| M. gilvum PYR-GCK | Mflv_2443 | - | 4e-17 | 31.93% (238) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. gilvum PYR-GCK | Mflv_2423 | - | 4e-17 | 30.77% (247) | L-carnitine dehydratase/bile acid-inducible protein F |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 1e-14 | 29.90% (204) | hypothetical protein Mb3300 |
| M. tuberculosis H37Rv | Rv3272 | - | 1e-14 | 29.90% (204) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0824 | - | 2e-18 | 34.00% (200) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_4757 | - | 4e-18 | 30.52% (249) | acyl-CoA transferase |
| M. avium 104 | MAV_4956 | - | 2e-94 | 55.68% (370) | hypothetical protein MAV_4956 |
| M. smegmatis MC2 155 | MSMEG_0262 | - | 1e-109 | 59.89% (364) | hypothetical protein MSMEG_0262 |
| M. thermoresistible (build 8) | TH_3339 | - | 7e-20 | 33.33% (195) | PUTATIVE putative L-carnitine dehydratase/bile acid-inducible |
| M. ulcerans Agy99 | MUL_0328 | - | 3e-17 | 29.72% (249) | acyl-CoA transferase |
| M. vanbaalenii PYR-1 | Mvan_0223 | - | 1e-131 | 65.94% (367) | hypothetical protein Mvan_0223 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3300|M.bovis_AF2122/97 --------------------------------------------------
Rv3272|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0824|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3339|M.thermoresistible__bu --------------------------------------------------
MMAR_4757|M.marinum_M MEATPPPVQPPLAGYRVVDLSTGIAGAYCTKLLADGGADVVKVEPPEGDP
MUL_0328|M.ulcerans_Agy99 MEATPPPVQPPLAGYRVVDLSTGIAGAYCTKLLADGGADVVKVEPPEGDP
Mflv_0444|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0223|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0262|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4956|M.avium_104 --------------------------------------------------
Mb3300|M.bovis_AF2122/97 --------------------------------------------------
Rv3272|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0824|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3339|M.thermoresistible__bu --------------------------------------------------
MMAR_4757|M.marinum_M LRWWSASGTAIPEGNDGALFNFLAGSQHSVVAAPEFDGDLALVEALLAAA
MUL_0328|M.ulcerans_Agy99 LRWCSASGTAIPEGNDGALFNFLAGSQHSVVAAPESDRDLALVEALLAAA
Mflv_0444|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0223|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0262|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4956|M.avium_104 --------------------------------------------------
Mb3300|M.bovis_AF2122/97 --------------------------------------------------
Rv3272|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0824|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3339|M.thermoresistible__bu --------------------------------------------------
MMAR_4757|M.marinum_M DAVVWSPGSRVAEHPRLGPQELHRRHPQLTVTSITPFGLEGPWHDRPATE
MUL_0328|M.ulcerans_Agy99 DAVVWSPGSRVAEHPRLGPQELHRRHPQLTVTSITPFGLDGPWHDRPATE
Mflv_0444|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0223|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0262|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4956|M.avium_104 --------------------------------------------------
Mb3300|M.bovis_AF2122/97 --------------------------------------------------
Rv3272|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0824|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3339|M.thermoresistible__bu --------------------------------------------------
MMAR_4757|M.marinum_M FTLQAWSGAIIGLGRGLADRAPVFVGGQVGEYLAGAYASVATLASRHRRI
MUL_0328|M.ulcerans_Agy99 FTLQAWSGAIIGLGRGLADRAPVFVGGRVGEYLAGAYASVATLASRHRRI
Mflv_0444|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0223|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0262|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4956|M.avium_104 --------------------------------------------------
Mb3300|M.bovis_AF2122/97 --------------------------------------------------
Rv3272|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0824|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3339|M.thermoresistible__bu --------------------------------------------------
MMAR_4757|M.marinum_M SDGWGELIDLSMLETQILSQTYYPVTYFEMLGRPWRDARRLTVPGVACAQ
MUL_0328|M.ulcerans_Agy99 SDGWGELIDLSMLETQILSQTYYPVTYFEMLGRPWRDARRLTVPGVACAQ
Mflv_0444|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0223|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0262|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4956|M.avium_104 --------------------------------------------------
Mb3300|M.bovis_AF2122/97 --------------------------------------------------
Rv3272|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0824|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3339|M.thermoresistible__bu --------------------------------------------------
MMAR_4757|M.marinum_M DGLVDLGCGTAQQWFDLCAMVGHPEWIDEQSPLSITEQANLHAEEIYEWL
MUL_0328|M.ulcerans_Agy99 DGLVDLGCGTAQQWFDLCAMVGHPEWIDEQSPLSITEQANLHAEEIYDWL
Mflv_0444|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0223|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0262|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4956|M.avium_104 --------------------------------------------------
Mb3300|M.bovis_AF2122/97 --------------------------------------------------
Rv3272|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0824|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3339|M.thermoresistible__bu --------------------------------------------------
MMAR_4757|M.marinum_M RSHPSDEIRELATAFRIPNAPVANGANIASLDHFQARGSFVRNPRDGFLQ
MUL_0328|M.ulcerans_Agy99 RSHPSDEIREIATAFRIPNAPVANGANIASLDHFQARGSFVRNPRDGFLQ
Mflv_0444|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0223|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0262|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4956|M.avium_104 --------------------------------------------------
Mb3300|M.bovis_AF2122/97 ---------------------------------------MPTSNPAKPLD
Rv3272|M.tuberculosis_H37Rv ---------------------------------------MPTSNPAKPLD
MAB_0824|M.abscessus_ATCC_1997 -------------------------------------------MTAAALD
TH_3339|M.thermoresistible__bu --------------------------------MTTEVETTATQPTTGPLH
MMAR_4757|M.marinum_M PAHPYRISSVHLRRPGPAPRLGEHGDHYRTAELKPRPVPTPKVLTRLPLS
MUL_0328|M.ulcerans_Agy99 PAHPYRISSVHLRRPGPAPRLGEHGYHYRTAELKPRPVPTPKVLTRLPLS
Mflv_0444|M.gilvum_PYR-GCK ------------------------------------------------MS
Mvan_0223|M.vanbaalenii_PYR-1 ------------------------------------MHRRGAVTHNGPVT
MSMEG_0262|M.smegmatis_MC2_155 ------------------------------------------------MT
MAV_4956|M.avium_104 ----------------------MGDVSAAATDWGGSGLAYLTGLPDGPAD
Mb3300|M.bovis_AF2122/97 GFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAARQITS----VLP
Rv3272|M.tuberculosis_H37Rv GFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAARQITS----VLP
MAB_0824|M.abscessus_ATCC_1997 GLLVVDFSRVLAGPYATMMLGDFGAEVIKIERPVLGDDTRQWG----PPY
TH_3339|M.thermoresistible__bu GIRVVEMGSLLAGPIVGQMMGDLGADVVKIEDPGKGDPLRQWG----QNR
MMAR_4757|M.marinum_M GIRVLDLTTFWAGPSCTHLLAMLGAEVIHVESTRRPDGTRLIAGVPVTED
MUL_0328|M.ulcerans_Agy99 GIRVLDLTTFWAGPSCTHLLAMLGAEVIHVESTRRPDGTRLIAGVPVTED
Mflv_0444|M.gilvum_PYR-GCK PVR--VPVAVLARAQ--AALGDLRADAEVLIG-GRAALLGLAP----DGR
Mvan_0223|M.vanbaalenii_PYR-1 SVR--IPAAVLEHARSTAARAGIAADTDELLG-GRAALLGLRS----GGR
MSMEG_0262|M.smegmatis_MC2_155 GISGAVAARAQQVADAFARMTGVAVDARVLLT-GRAALLGMCP----QGC
MAV_4956|M.avium_104 FSRAPVLSRAHQVAAAIGARLGVDAAAAVLLS-GRAALLGLRR----AGQ
. . . . :
Mb3300|M.bovis_AF2122/97 GRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTADVVLEAFRPGT
Rv3272|M.tuberculosis_H37Rv GRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTADVVLEAFRPGT
MAB_0824|M.abscessus_ATCC_1997 DSDGQATYFNSVNRNKQSVVLDLTSPDGQHRARELAGRADVVVENFRAGT
TH_3339|M.thermoresistible__bu PK-GQSLWFSIVGRNKRSVTINLREPRGQELVRQLVAEADVLVENFRPGT
MMAR_4757|M.marinum_M QWWEKSPIFVALNTNKKGVTLDLGDSRGREVLHRLIATCDVIAENFTPRV
MUL_0328|M.ulcerans_Agy99 QWWEKSPIFVALNTNKKGGTLDLGDSRGREVLHRLIATCDVIAENFTPRV
Mflv_0444|M.gilvum_PYR-GCK ISAGGATRLLAGPDG--WCALTLSRPDDVDAVPALLGADDLPDDMWSAIG
Mvan_0223|M.vanbaalenii_PYR-1 VSAGGASRLMAAHDG--WCALTLSRPDDIAAVPALVEADAVVGDPWPAVE
MSMEG_0262|M.smegmatis_MC2_155 ISAGGATHLFPSRKGT-WCALTLSRPDDVAAVPALVQADTVDADPWPVVE
MAV_4956|M.avium_104 VSPGGATRLLAARDD--HCALTLSRADDLAAVPALLQVDDMAGDPWPALR
: : . .: * * : : :
Mb3300|M.bovis_AF2122/97 MEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDLVVAAEAGMTT
Rv3272|M.tuberculosis_H37Rv MEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDLVVAAEAGMTT
MAB_0824|M.abscessus_ATCC_1997 MEKFGLGYQSLKQLNPGLIYCAITGFG-RGAGADLPGYDLLVQAVGGLMS
TH_3339|M.thermoresistible__bu MERWGLGYSDLAEINPRLVIVRVSGFGQDGPYASRPGYGAIGEAMGGLRY
MMAR_4757|M.marinum_M LDQLGLDFTTVQSIRSDAILLRMPGFGLDGPWRDNPAFAYVIESAAGISW
MUL_0328|M.ulcerans_Agy99 MDQLGLDFATVQSIRSDAILLRMPGFGLDGPWRDNPAFAYVIESAAGISW
Mflv_0444|M.gilvum_PYR-GCK RVIAETGVWVFAER-ARLLGLPVGVLGEATEAPTALCRNGERKAFGDLNG
Mvan_0223|M.vanbaalenii_PYR-1 RNVHDRGVVAFAER-ARLLGLPVGVLGETGSAAPVFRRSGDPVQPCGLTG
MSMEG_0262|M.smegmatis_MC2_155 TWAAATEAHAITER-ARLLGLPAAVLGETVPAAPRITRMWPRGTGRPLTG
MAV_4956|M.avium_104 CWAAGRATAEIVER-ATLLDIPAAALGEARPAAERIQPIAPGGAPRSPRG
. . . : *
Mb3300|M.bovis_AF2122/97 GMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERNGVADVVQVAMY
Rv3272|M.tuberculosis_H37Rv GMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERNGVADVVQVAMY
MAB_0824|M.abscessus_ATCC_1997 VTGPDAAHPSKVGVALVDVLTALHALSGILAALSYRDRTGQGQRVDTDLM
TH_3339|M.thermoresistible__bu VVGDPSTPPSRVGISIGDTLAALFATIGALAALREREISGRGQMVDSAIY
MMAR_4757|M.marinum_M MTGYPDLTP-YEPYSVGDPNAGVHAANALLLALEHRRRTGRGVLVEAAMV
MUL_0328|M.ulcerans_Agy99 MTGYPDLTP-YEPYSVGDPNAGVHAANALLLALEHRRRTGRGVLVEAAMV
Mflv_0444|M.gilvum_PYR-GCK LLVADLSSMWAGPLCGRLLSDAGATVVKVETRTRPDGTRQGSAAFFDWMN
Mvan_0223|M.vanbaalenii_PYR-1 LLVADLSSMWAGPLCGQLLARAGATVVKVESATRPDGTRQGPPTFFDWMN
MSMEG_0262|M.smegmatis_MC2_155 LLVADLSSMWAGPLCGQLLRQAGATVVKVESHARPDGTRNGPQVFFDWMN
MAV_4956|M.avium_104 LLVADLSSMWAGPLCGQLLARAGATVVKVESPRRPDGTRAGNRAFFDWMN
. . :
Mb3300|M.bovis_AF2122/97 DVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGVGFATQPSDAFRTA
Rv3272|M.tuberculosis_H37Rv DVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGVGFATQPSDAFRTA
MAB_0824|M.abscessus_ATCC_1997 SVLLSSLVNQASGYLGAGVVPEALGNRHP----------SIAPYQTFETA
TH_3339|M.thermoresistible__bu EAVLGVMESLVPEWTVSGYQRERTGAILP----------KIAPSNVYPTS
MMAR_4757|M.marinum_M DAALNIAAEQVIEYSAYGRLLERAGNRGPAAVPQN--LYRSSDIDEFGRL
MUL_0328|M.ulcerans_Agy99 DAALNIAAEQVIEYSAYGRLLERAGNRGPAAVPQN--LYRSSDIDEFGRL
Mflv_0444|M.gilvum_PYR-GCK SGKLAYAADLE-DP-GLRRLLGAADVVIE----------SSRPAALQRRG
Mvan_0223|M.vanbaalenii_PYR-1 GGKLSYRADFT-RPDGVRRLLAVADVVIE----------SSRPAALERRG
MSMEG_0262|M.smegmatis_MC2_155 HGKLSYVADFG-EPSALGALLDVADVVIE----------SSRPTALVRRG
MAV_4956|M.avium_104 HGKLCYGIDFDRDADQLRELLTVSDIVIE----------GSRPAALRRRG
: .
Mb3300|M.bovis_AF2122/97 DG-YIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQRSRSINYAELTAEL
Rv3272|M.tuberculosis_H37Rv DG-YIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQRSRSINYAELTAEL
MAB_0824|M.abscessus_ATCC_1997 DR-PIAIAVGNDKQFRLLVQALEMPRLARDDRFATNPLRVRHRGELVRVL
TH_3339|M.thermoresistible__bu DDTWILIAANQDTVFRRLAEAMGRPELAEDERYATHVARGEHQAELDEIV
MMAR_4757|M.marinum_M DS-WVAIAVSTDQHWQQLGAALGSPSWAAEPRLATAAGRRTHEDVIDDHL
MUL_0328|M.ulcerans_Agy99 DS-WVAIAVSTDQHWQQLGAALGSPSWAAEPRLATAAGRRTHEDVIDDHL
Mflv_0444|M.gilvum_PYR-GCK LG-PTDVAGPAGRVWVRITGHGTDGARADWVAFGDDAAVSGGLVSGSPAD
Mvan_0223|M.vanbaalenii_PYR-1 LG-PADVPARRGRIWLRVTGHGTAGDRADWVAFGDDAAVSGGLVGGSADA
MSMEG_0262|M.smegmatis_MC2_155 LG-PDVVASREGRVWVRITGHGTTGEHADWVAFGDDAAVSGGLVKNHHGT
MAV_4956|M.avium_104 LG-PADIAPRPGRIWLQITAFD-----DDRPGFGDDAAVGGGLVGTSAAG
:. : : .
Mb3300|M.bovis_AF2122/97 ELALASKTATEWVQLLQANGLMACLAHTWKQVVDTPLFAESDLTLEVGRG
Rv3272|M.tuberculosis_H37Rv ELALASKTATEWVQLLQANGLMACLAHTWKQVVDTPLFAENDLTLEVGRG
MAB_0824|M.abscessus_ATCC_1997 EQRLREKNADDWYDTLTAVGVPAGPINDIAEAFRFAERLGLDVAVTVPGS
TH_3339|M.thermoresistible__bu AEFTRRHTAAEVEALMHKHNVPVGKIYRPKEMLADPQFRARESITSVDHP
MMAR_4757|M.marinum_M TAWCGQRGSDEIVATLWQAGVPVAKVMQPHRQSELAQLASRGFFEVVDHP
MUL_0328|M.ulcerans_Agy99 TAWCGQRGSDEIVATLWQAGVPVAKVMQPHRQSELAQLASRGFFEVVDHP
Mflv_0444|M.gilvum_PYR-GCK PRFCGDAIADPLTGIRAAAEVLASRRRGGGELIELSMAGVAAEYAQL---
Mvan_0223|M.vanbaalenii_PYR-1 PEFCGDAIADPLTGLHAALAVLESHARGGGELVEISMAAVAAGYAGL---
MSMEG_0262|M.smegmatis_MC2_155 PSFAGDAIADPLTGLHAAHAVAESLTRGGGDLIEFAMSAVAATYADL---
MAV_4956|M.avium_104 PVFCGDAIADPLTGLHAALAVAESLGRGGGELIRLSMAGVAAGYAALG--
: : . :
Mb3300|M.bovis_AF2122/97 ADTITVIRTPAR-YASFR-AVVTDPPPTAGEHNAVFLARP----------
Rv3272|M.tuberculosis_H37Rv ADTITVIRTPAR-YASFR-AVVTDPPPTAGEHNAVFLARP----------
MAB_0824|M.abscessus_ATCC_1997 PE--PQVANPIS-MSKTP-VVYRNGPPRLGQSRA----------------
TH_3339|M.thermoresistible__bu VLGEIQMQNVFPRLSRTR-GSIRWPGPGLGEHTDEVLRQLGLSDEELQKL
MMAR_4757|M.marinum_M VNGPVRLSTVPMRLSGWPGRFHTEPAPLLGQHNRELLTELGLTAAEISEL
MUL_0328|M.ulcerans_Agy99 VNGPVRLSTVPMRLSGWPGRFHTEPAPLLGQHNRELLTELGLTAAEISEL
Mflv_0444|M.gilvum_PYR-GCK ------PRGDEKPCVATPVAAPRGPA--LGADNAAVDRLVADRATLPC--
Mvan_0223|M.vanbaalenii_PYR-1 ------PGDDERYCAATPSVPDSGPE--LGSGNDVVDRLVADRLAAPC--
MSMEG_0262|M.smegmatis_MC2_155 ------ATTGADIATVEPASAPAGPA--LGADNGAVTRLIAG--SRPC--
MAV_4956|M.avium_104 ----TEPPTSDAPVSPPAPPPPSGPASALGADNAAVRHLVSQRRCRSC--
*
Mb3300|M.bovis_AF2122/97 ----------------
Rv3272|M.tuberculosis_H37Rv ----------------
MAB_0824|M.abscessus_ATCC_1997 ----------------
TH_3339|M.thermoresistible__bu HDAGVV----------
MMAR_4757|M.marinum_M ESDGVIGAAPAMYSAT
MUL_0328|M.ulcerans_Agy99 ESDGVIGAAPAMYSAT
Mflv_0444|M.gilvum_PYR-GCK ----------------
Mvan_0223|M.vanbaalenii_PYR-1 ----------------
MSMEG_0262|M.smegmatis_MC2_155 ----------------
MAV_4956|M.avium_104 ----------------