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GDVSAAATDWGGSGLAYLTGLPDGPADFSRAPVLSRAHQVAAAIGARLGVDAAAAVLLSGRAALLGLRRA GQVSPGGATRLLAARDDHCALTLSRADDLAAVPALLQVDDMAGDPWPALRCWAAGRATAEIVERATLLDI PAAALGEARPAAERIQPIAPGGAPRSPRGLLVADLSSMWAGPLCGQLLARAGATVVKVESPRRPDGTRAG NRAFFDWMNHGKLCYGIDFDRDADQLRELLTVSDIVIEGSRPAALRRRGLGPADIAPRPGRIWLQITAFD DDRPGFGDDAAVGGGLVGTSAAGPVFCGDAIADPLTGLHAALAVAESLGRGGGELIRLSMAGVAAGYAAL GTEPPTSDAPVSPPAPPPPSGPASALGADNAAVRHLVSQRRCRSC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4956 | - | - | 100% (396) | hypothetical protein MAV_4956 |
| M. avium 104 | MAV_5261 | - | 3e-16 | 33.33% (207) | caib/baif family protein |
| M. avium 104 | MAV_0893 | - | 8e-16 | 31.54% (241) | caib/baif family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 4e-14 | 29.36% (235) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_0444 | - | 3e-94 | 55.68% (370) | hypothetical protein Mflv_0444 |
| M. tuberculosis H37Rv | Rv3272 | - | 4e-14 | 29.36% (235) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0824 | - | 8e-16 | 31.94% (216) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_1267 | - | 3e-17 | 31.78% (236) | acyl-CoA transferase |
| M. smegmatis MC2 155 | MSMEG_0262 | - | 1e-101 | 58.08% (365) | hypothetical protein MSMEG_0262 |
| M. thermoresistible (build 8) | TH_3339 | - | 7e-16 | 30.34% (178) | PUTATIVE putative L-carnitine dehydratase/bile acid-inducible |
| M. ulcerans Agy99 | MUL_2621 | - | 2e-17 | 31.78% (236) | acyl-CoA transferase |
| M. vanbaalenii PYR-1 | Mvan_0223 | - | 1e-104 | 57.26% (379) | hypothetical protein Mvan_0223 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4956|M.avium_104 MGDVSAAATDWGGSGLAYLTGLPDGPADFSRAPVLSRAHQVAAAIGARLG
MSMEG_0262|M.smegmatis_MC2_155 ------------------MTGISG--------AVAARAQQVADAFARMTG
Mflv_0444|M.gilvum_PYR-GCK ---------------------MSP-------VRVPVAVLARAQ--AALGD
Mvan_0223|M.vanbaalenii_PYR-1 ---------MHRRGAVTHNGPVTS-------VRIPAAVLEHARSTAARAG
Mb3300|M.bovis_AF2122/97 ------------MPTSNPAKPLDG-------FRVLDFTQNVAGPLAGQVL
Rv3272|M.tuberculosis_H37Rv ------------MPTSNPAKPLDG-------FRVLDFTQNVAGPLAGQVL
MMAR_1267|M.marinum_M ------------MPEGNPAKPLDG-------FRVLDFTQNVAGPLAGQVL
MUL_2621|M.ulcerans_Agy99 ------------MPEGNPAKPLDG-------FRVLDFTQNVAGPLAGQVL
MAB_0824|M.abscessus_ATCC_1997 ----------------MTAAALDG-------LLVVDFSRVLAGPYATMML
TH_3339|M.thermoresistible__bu -----MTTEVETTATQPTTGPLHG-------IRVVEMGSLLAGPIVGQMM
: : *
MAV_4956|M.avium_104 VDAAAAVLLS---GRAALLGLRRAGQVSPGGATRLLAAR--DDHCALTLS
MSMEG_0262|M.smegmatis_MC2_155 VAVDARVLLT---GRAALLGMCPQGCISAGGATHLFPSRK-GTWCALTLS
Mflv_0444|M.gilvum_PYR-GCK LRADAEVLIG---GRAALLGLAPDGRISAGGATRLLAGP--DGWCALTLS
Mvan_0223|M.vanbaalenii_PYR-1 IAADTDELLG---GRAALLGLRSGGRVSAGGASRLMAAH--DGWCALTLS
Mb3300|M.bovis_AF2122/97 VDLGAEVIKVEAPGGEAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLT
Rv3272|M.tuberculosis_H37Rv VDLGAEVIKVEAPGGEAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLT
MMAR_1267|M.marinum_M ADLGAEVIKVEAPGGEAARHITAVLPHRPPLATYFLPNNRGKKSVSVDLS
MUL_2621|M.ulcerans_Agy99 ADLGAEVIKVEAPGGEAARHITAVLPHRPPLATYFLPNNRGKKSVSVDLS
MAB_0824|M.abscessus_ATCC_1997 GDFGAEVIKIERPVLGDDTRQWGPPYDSDGQATYFNSVNRNKQSVVLDLT
TH_3339|M.thermoresistible__bu GDLGADVVKIEDPGKGDPLRQWGQ-NRPKGQSLWFSIVGRNKRSVTINLR
: : : : : *
MAV_4956|M.avium_104 RADDLAAVPALLQVDDMAGDPWPALRCWAAGRATAEIVER-ATLLDIPAA
MSMEG_0262|M.smegmatis_MC2_155 RPDDVAAVPALVQADTVDADPWPVVETWAAATEAHAITER-ARLLGLPAA
Mflv_0444|M.gilvum_PYR-GCK RPDDVDAVPALLGADDLPDDMWSAIGRVIAETGVWVFAER-ARLLGLPVG
Mvan_0223|M.vanbaalenii_PYR-1 RPDDIAAVPALVEADAVVGDPWPAVERNVHDRGVVAFAER-ARLLGLPVG
Mb3300|M.bovis_AF2122/97 TEQAKQQMLRLADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLT
Rv3272|M.tuberculosis_H37Rv TEQAKQQMLRLADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLT
MMAR_1267|M.marinum_M TDTARRQILRLADTADVVLEGFRPGVMERMGLGPEDLRARNPKLIYARLS
MUL_2621|M.ulcerans_Agy99 TDTARRQILRLADTADVVLEGFRPGVMERMGLGPEDLRARNPKLIYARLS
MAB_0824|M.abscessus_ATCC_1997 SPDGQHRARELAGRADVVVENFRAGTMEKFGLGYQSLKQLNPGLIYCAIT
TH_3339|M.thermoresistible__bu EPRGQELVRQLVAEADVLVENFRPGTMERWGLGYSDLAEINPRLVIVRVS
* : : : : . *:
MAV_4956|M.avium_104 ALGEARPAAERIQPIAPGGAPRSPRGLLVADLS--SMWAGPLCGQLLARA
MSMEG_0262|M.smegmatis_MC2_155 VLGETVPAAPRITRMWPRGTGRPLTGLLVADLS--SMWAGPLCGQLLRQA
Mflv_0444|M.gilvum_PYR-GCK VLGEATEAPTALCRNGERKAFGDLNGLLVADLS--SMWAGPLCGRLLSDA
Mvan_0223|M.vanbaalenii_PYR-1 VLGETGSAAPVFRRSGDPVQPCGLTGLLVADLS--SMWAGPLCGQLLARA
Mb3300|M.bovis_AF2122/97 AYGGNGPHGSRPGIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHV
Rv3272|M.tuberculosis_H37Rv AYGGNGPHGSRPGIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHV
MMAR_1267|M.marinum_M AFGGNGPHGTRPGVDLMVAAEAGMTTGMPTPDGKPQIIPFQLVDNASGHV
MUL_2621|M.ulcerans_Agy99 AFGGNGPHGTRPGVDLMVAAEAGMTTGMPTPDGKPQIIPFQLVDNASGHV
MAB_0824|M.abscessus_ATCC_1997 GFGR-GAGADLPGYDLLVQAVGGLMSVTGPDAAHPSKVGVALVDVLTALH
TH_3339|M.thermoresistible__bu GFGQDGPYASRPGYGAIGEAMGGLRYVVGDPSTPPSRVGISIGDTLAALF
* . : .
MAV_4956|M.avium_104 GATVVKVESPRRPDGTRAG--NRAFFDWMNHGKLCYGIDFDRDAD-----
MSMEG_0262|M.smegmatis_MC2_155 GATVVKVESHARPDGTRNG--PQVFFDWMNHGKLSYVADFG-EPS-----
Mflv_0444|M.gilvum_PYR-GCK GATVVKVETRTRPDGTRQG--SAAFFDWMNSGKLAYAADLE-DP------
Mvan_0223|M.vanbaalenii_PYR-1 GATVVKVESATRPDGTRQG--PPTFFDWMNGGKLSYRADFT-RPD-----
Mb3300|M.bovis_AF2122/97 LAQAVLAALLHRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPK
Rv3272|M.tuberculosis_H37Rv LAQAVLAALLHRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPK
MMAR_1267|M.marinum_M LAQAVLAALLNRERHGVADTVRVAMYDVAVGLQANQLTMHLNRPSSDAPK
MUL_2621|M.ulcerans_Agy99 LAQAVLAALLNRERHGVADTVRVAMYDVAVGLQANQLTMHLNRPSSDAPK
MAB_0824|M.abscessus_ATCC_1997 ALSGILAALSYRDRTGQGQRVDTDLMSVLLSSLVNQASGYLGAG------
TH_3339|M.thermoresistible__bu ATIGALAALREREISGRGQMVDSAIYEAVLGVMESLVPEWTVSG------
. * : .
MAV_4956|M.avium_104 --QLRELLTVSDIVIEGSRPAALRRRGLGP-ADIAPRPGRIWLQITAFDD
MSMEG_0262|M.smegmatis_MC2_155 --ALGALLDVADVVIESSRPTALVRRGLGP-DVVASREGRVWVRITGHGT
Mflv_0444|M.gilvum_PYR-GCK --GLRRLLGAADVVIESSRPAALQRRGLGP-TDVAGPAGRVWVRITGHGT
Mvan_0223|M.vanbaalenii_PYR-1 --GVRRLLAVADVVIESSRPAALERRGLGP-ADVPARRGRIWLRVTGHGT
Mb3300|M.bovis_AF2122/97 -PEPAPKAKRRKGVGFATQPSDAFRTADGY-IVISAYVPKHWQKLCYLIG
Rv3272|M.tuberculosis_H37Rv -PEPAPKAKRRKGVGFATQPSDAFRTADGY-IVISAYVPKHWQKLCYLIG
MMAR_1267|M.marinum_M RPEQTPAGARRKRVAFATQPSDAFRAADGY-LLISAYVPKHWQRLCEIIG
MUL_2621|M.ulcerans_Agy99 RPEQTPAGARRKRVAFATQPSDAFRAADGY-LLISAYVPKHWQRLCEIIG
MAB_0824|M.abscessus_ATCC_1997 -----VVPEALGNRHPSIAPYQTFETADRP-IAIAVGNDKQFRLLVQALE
TH_3339|M.thermoresistible__bu -----YQRERTGAILPKIAPSNVYPTSDDTWILIAANQDTVFRRLAEAMG
* . :. : :
MAV_4956|M.avium_104 -----DRPGFGDDAAVGGGLVGTSAAGPVFCGDAIADPLTGLHAALAVAE
MSMEG_0262|M.smegmatis_MC2_155 TGEHADWVAFGDDAAVSGGLVKNHHGTPSFAGDAIADPLTGLHAAHAVAE
Mflv_0444|M.gilvum_PYR-GCK DGARADWVAFGDDAAVSGGLVSGSPADPRFCGDAIADPLTGIRAAAEVLA
Mvan_0223|M.vanbaalenii_PYR-1 AGDRADWVAFGDDAAVSGGLVGGSADAPEFCGDAIADPLTGLHAALAVLE
Mb3300|M.bovis_AF2122/97 RPDLVEDQRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMA
Rv3272|M.tuberculosis_H37Rv RPDLVEDQRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMA
MMAR_1267|M.marinum_M RPDLLDDERFIDQRARAINYAELTEELESALAAKTAAQWVELLHEGGLMA
MUL_2621|M.ulcerans_Agy99 QPDLLDDERFIDQRARAINYAELTEELESALAAKTAAQWVELLHEGGLMA
MAB_0824|M.abscessus_ATCC_1997 MPRLARDDRFATNPLRVRHRGELVRVLEQRLREKNADDWYDTLTAVGVPA
TH_3339|M.thermoresistible__bu RPELAEDERYATHVARGEHQAELDEIVAEFTRRHTAAEVEALMHKHNVPV
: . * :
MAV_4956|M.avium_104 SLGRGGGELIRLSMAGVAAGYAALGTEPPTSDAPVSPPAPPPPSGPASAL
MSMEG_0262|M.smegmatis_MC2_155 SLTRGGGDLIEFAMSAVAATYADLATTG--ADIATVEPASAP-AGP--AL
Mflv_0444|M.gilvum_PYR-GCK SRRRGGGELIELSMAGVAAEYAQLPRGD---EKPCVATPVAAPRGP--AL
Mvan_0223|M.vanbaalenii_PYR-1 SHARGGGELVEISMAAVAAGYAGLPGDD---ERYCAATPSVPDSGP--EL
Mb3300|M.bovis_AF2122/97 CLAHTWKQVVDTPLFAESDLTLEVGRGA--DTITVIRTPARYASFR-AVV
Rv3272|M.tuberculosis_H37Rv CLAHTWKQVVDTPLFAENDLTLEVGRGA--DTITVIRTPARYASFR-AVV
MMAR_1267|M.marinum_M CLAYTWKQVVTTPLFAENELALQVGSGD--DAVTVIRTPARYSSFS-AVL
MUL_2621|M.ulcerans_Agy99 CLAYTWKQVVTTPLFAENELALQVDSGD--DAVTVIRTPARYSSFS-AVL
MAB_0824|M.abscessus_ATCC_1997 GPIN---DIAEAFRFAERLGLDVAVTVPGSPEPQVANPIS-MSKTP-VVY
TH_3339|M.thermoresistible__bu GKIYRPKEMLADPQFRARESIT-SVDHPVLGEIQMQNVFPRLSRTR-GSI
::
MAV_4956|M.avium_104 GADNAAVRHLVSQRRCRSC---------------
MSMEG_0262|M.smegmatis_MC2_155 GADNGAVTRLIAG--SRPC---------------
Mflv_0444|M.gilvum_PYR-GCK GADNAAVDRLVADRATLPC---------------
Mvan_0223|M.vanbaalenii_PYR-1 GSGNDVVDRLVADRLAAPC---------------
Mb3300|M.bovis_AF2122/97 TDPPPTAGEHNAVFLARP----------------
Rv3272|M.tuberculosis_H37Rv TDPPPTAGEHNAVFLARP----------------
MMAR_1267|M.marinum_M AEPPAATGEHNETLLGES----------------
MUL_2621|M.ulcerans_Agy99 ADPPPATGEHNETLLGES----------------
MAB_0824|M.abscessus_ATCC_1997 RNGPPRLGQSRA----------------------
TH_3339|M.thermoresistible__bu RWPGPGLGEHTDEVLRQLGLSDEELQKLHDAGVV
.