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PAARRRRGRPAGSRVDPDERRTALLDAAERAIRAKGPSAGLVDIAGEAGFVRSAVYAMYPGRDALLAELS RRTAQRLLGEITTRAAGSTDLRQRMALFFDVISAWMQAEPNLYRALTGEPSTSVFEQLAGAVEQMLTTSS GSEQARRAAAPWSRAIVGSAVSAAEWWCRAGTMPRAELVEHLTALCWDGGAALPFNADDIRTIDSGPH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3154 | - | - | 100% (209) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4678 | - | 8e-10 | 26.92% (182) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4155 | - | 1e-07 | 24.55% (220) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3233 | - | 1e-08 | 24.64% (207) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0366 | - | 2e-14 | 30.00% (180) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3208 | - | 1e-08 | 24.64% (207) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02457 | - | 1e-09 | 24.75% (202) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2812 | - | 1e-27 | 36.27% (193) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0797 | - | 8e-10 | 25.74% (202) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0916 | - | 3e-11 | 25.91% (220) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0865 | - | 1e-12 | 28.71% (202) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_4540 | - | 4e-10 | 25.74% (202) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3360 | - | 1e-83 | 74.38% (203) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3154|M.avium_104 ----------------MPAARRRRG-----------RPAGSRVDPDERRT
Mvan_3360|M.vanbaalenii_PYR-1 ----------------MEAEKRRRG-----------RPTGSRVDPGERRA
MAB_2812|M.abscessus_ATCC_1997 ------------------MATRGRG-----------RPSGAPYDRKLRTE
MSMEG_0916|M.smegmatis_MC2_155 -----------MAQQTPPATVKTDG-----------RKRRWHQHKVERRN
TH_0865|M.thermoresistible__bu -----------VGQQTPPAAVKMDG-----------RKRRWHQHKVERRN
MMAR_0797|M.marinum_M -----------MVERIPAMTGKTDG-----------RKRRWHQHKVERRN
MUL_4540|M.ulcerans_Agy99 ------------------MTGKTDG-----------RKRRWHQHKVERRN
MLBr_02457|M.leprae_Br4923 -----------MAEHIPAVAVKTDG-----------RKRRWHQHKVERRN
Mb3233|M.bovis_AF2122/97 --------MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRG
Rv3208|M.tuberculosis_H37Rv --------MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRG
Mflv_0366|M.gilvum_PYR-GCK MAEADSEPFAPSASGRSTSPARRRG-----------RPVGGGNTSDQART
: * .
MAV_3154|M.avium_104 ALLDAAERAIRAKGPSAG-LVDIAGEAGFVRSAVYAMYPGRDALLAELSR
Mvan_3360|M.vanbaalenii_PYR-1 LLLDAAERAIRANGPDVG-LGDVAAEAGFVRSAVYAMYPNRDALLAALSE
MAB_2812|M.abscessus_ATCC_1997 ELLDAAERAIRNSGGTVS-IAEVAREAGFARSACYAVFPTKADLLRSLSR
MSMEG_0916|M.smegmatis_MC2_155 ELVDGTLEAIRRRGSNVS-MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMM
TH_0865|M.thermoresistible__bu ELVDGTLEAIRRRGSNVS-MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMM
MMAR_0797|M.marinum_M ELVDGTIVAIRRHGRFLS-MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMM
MUL_4540|M.ulcerans_Agy99 ELVDGTIVAIRRHGRFLS-MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMM
MLBr_02457|M.leprae_Br4923 ELVDGTIDAIRRQGRFLS-MDEIAGKIGVSKTVLYRYFIDKNDLTTAVMM
Mb3233|M.bovis_AF2122/97 QLLVVASDVFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLH
Rv3208|M.tuberculosis_H37Rv QLLVVASDVFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLH
Mflv_0366|M.gilvum_PYR-GCK VLMDAAERSILRRGFQASTMELVAREAGYSRAAIYRHFPSRRLLLEALVE
*: : : * . : :* . * :.. * : : * :
MAV_3154|M.avium_104 RTAQR-LLGEITTRAAGSTDLRQRMALFFDVISAWMQAEPNLYRALTGEP
Mvan_3360|M.vanbaalenii_PYR-1 RTAQR-LLADITRRAEGSSDLRQRMALFFDVVCGWIAAEPDVHRALNSDP
MAB_2812|M.abscessus_ATCC_1997 RHADR-LISGAWQHSMVG-DTRDQIRAFSTLVIDWISAEPELYIALDRDL
MSMEG_0916|M.smegmatis_MC2_155 RFAQTTLIPNMAAALSSNLDGFALTREIIRVYVETVAAEPEPYRFVMANN
TH_0865|M.thermoresistible__bu RFAQTTLIPNMAAALSTDLDGYDLTREIIRVYVETVAAEPEPYRFVMANN
MMAR_0797|M.marinum_M RFAQTTLIPNMAAALSSNLDGFDLAREIIRVYVETVAAEPEPYRFVMANS
MUL_4540|M.ulcerans_Agy99 RFAQTTLIPNMAAALSSNLDGFDLAREIIRVYVETVAAEPEPYRFVMANS
MLBr_02457|M.leprae_Br4923 RFAQTTLIPNMAAALSTNLDGFDLTREIIRVYVKTVAAEPEPYQFVMANS
Mb3233|M.bovis_AF2122/97 RHVEN-LVSGVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFEND
Rv3208|M.tuberculosis_H37Rv RHVEN-LVSGVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFEND
Mflv_0366|M.gilvum_PYR-GCK RKTRR-HQTEISARLTENASLADLLTEGLVIVATELIHDPLLRTLSEQTD
* . . : :.
MAV_3154|M.avium_104 ------STSVFEQLAGAVEQMLTTSSGSEQ--ARRAAAPWSRAIVGSAVS
Mvan_3360|M.vanbaalenii_PYR-1 ------ATGVFEQLAAAVEFMLTAAFAADA--RAPASAPWSRAIVGSAVS
MAB_2812|M.abscessus_ATCC_1997 TAQEQLDHGVFDLIAQVTEEHLHAQFPGDQ--MTRLAPIWSRLAVGGVLM
MSMEG_0916|M.smegmatis_MC2_155 SASKSKAVADSEQIIARMLAVMLRRRMAEVGMDTGGVEAWAFHTVGGVQL
TH_0865|M.thermoresistible__bu SAGKSKVVADSERIIARMLGVMLRRRMAEAGMDTRGVEPWSNLIVGGVQL
MMAR_0797|M.marinum_M SASKSKVIADSERIIARMLAVMLRRRMAEAGMDTGGVEPWAYLIVGGVQL
MUL_4540|M.ulcerans_Agy99 SASKSKVIADSERIIARMLAVMLRRRVAEAGMDTGGVEPWAYLIVGGVQL
MLBr_02457|M.leprae_Br4923 SASKSKVIADSERIIARMLAVMIRRRMQEAGMDAGGVEPWAYLIVGGVQL
Mb3233|M.bovis_AF2122/97 FVTEPEVAAQVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVD
Rv3208|M.tuberculosis_H37Rv FVTEPEVAAQVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVD
Mflv_0366|M.gilvum_PYR-GCK EGTVAHLVAGAARIPEQVEQLIAATDGGES--EKIFRPGVEAGDVGQFLI
. : : **
MAV_3154|M.avium_104 AAEWWCRAGT-MPRAELVEHLTALCWDGGAALPFNADDIRTIDSGPH---
Mvan_3360|M.vanbaalenii_PYR-1 AAEWWCRTGT-MTRAELVEHLTALCWDGGAALPFVDDDIKAIDIRRP---
MAB_2812|M.abscessus_ATCC_1997 TINWWSASRT-MTQDDLIGYIVETFAEG------IGEGSRLVAANC----
MSMEG_0916|M.smegmatis_MC2_155 ATHSWMSNPR-MTSDELIDYLTMLSWYALCGIVEVGGSLEKFNSQPHPSP
TH_0865|M.thermoresistible__bu ATHSWMSHPR-MTSDELIDYLTMLSWSALCGIVEVGGSLEKFREMPHPSX
MMAR_0797|M.marinum_M ATHSWMSDPR-MTSDELIDYLTMLSWSALCGIVEAGGSLEKFRDQPHPSP
MUL_4540|M.ulcerans_Agy99 ATHSWMSDPR-MTSDELIDYLTMLSWSALCGIVEAGGSLEKFRDQPHPSP
MLBr_02457|M.leprae_Br4923 ATHSWMSDPR-MSADELIDYLTMLSWNALCGIVEVGGSLEKFRKQPHPSP
Mb3233|M.bovis_AF2122/97 CARYWLDADKPISKSDAVEGTVQFAWGGLSHVPLTRS-------------
Rv3208|M.tuberculosis_H37Rv CARYWLDADKPISKSDAVEGTVQFAWGGLSHVPLTRS-------------
Mflv_0366|M.gilvum_PYR-GCK TAALTMLLGV-IPGIEDPETARRYVRTFVLPAILADPPAPQQVFRPR---
:. :
MAV_3154|M.avium_104 --------------------------------------------------
Mvan_3360|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2812|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0916|M.smegmatis_MC2_155 ---------------------------IPP--------------------
TH_0865|M.thermoresistible__bu XSSSLSGNGLNSPQPWGPSISMPSRTAAPPDIPTVGIANSGAVSKSISVC
MMAR_0797|M.marinum_M --------------------------IVPP--------------------
MUL_4540|M.ulcerans_Agy99 --------------------------IVPP--------------------
MLBr_02457|M.leprae_Br4923 --------------------------IIPP--------------------
Mb3233|M.bovis_AF2122/97 --------------------------------------------------
Rv3208|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0366|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3154|M.avium_104 ---------------------------
Mvan_3360|M.vanbaalenii_PYR-1 ---------------------------
MAB_2812|M.abscessus_ATCC_1997 ---------------------------
MSMEG_0916|M.smegmatis_MC2_155 --RHLLD--------------------
TH_0865|M.thermoresistible__bu TERKLADRARKRPEPGIRPGTRNRRRS
MMAR_0797|M.marinum_M ---RVDD--------------------
MUL_4540|M.ulcerans_Agy99 ---RVDD--------------------
MLBr_02457|M.leprae_Br4923 ---RGP---------------------
Mb3233|M.bovis_AF2122/97 ---------------------------
Rv3208|M.tuberculosis_H37Rv ---------------------------
Mflv_0366|M.gilvum_PYR-GCK ---------------------------