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M. gilvum PYR-GCK Mflv_0203 (-)

annotation: anti-sigma-factor antagonist
coordinates: 187854 - 188312
length: 152

MAISEALPPSSTQRVFRPDPTSFELREEHHRATFSACELPPTTVLVTIHGEIDATNNMPLAHYIEKRIGD
SRKLIVDLQTVEFFAASGFAALFNVNVVCHRRGVRWQLLAGPHVRRLLRVCDPQRELPVTGSSAKYTRTR
PRDRKLLVGGYH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0203--100% (152)anti-sigma-factor antagonist
M. gilvum PYR-GCKMflv_3879-4e-2441.53% (118) anti-sigma-factor antagonist
M. gilvum PYR-GCKMflv_4788-3e-1737.00% (100) anti-sigma-factor antagonist

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1939-7e-0826.32% (133) hypothetical protein Mb1939
M. tuberculosis H37RvRv1904-7e-0826.32% (133) hypothetical protein Rv1904
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2512-2e-1136.73% (98) hypothetical protein MAB_2512
M. marinum MMMAR_0853-1e-0836.49% (74) hypothetical protein MMAR_0853
M. avium 104MAV_4257-2e-1841.49% (94) STAS domain-containing protein
M. smegmatis MC2 155MSMEG_1786-1e-1438.14% (97) STAS domain-containing protein
M. thermoresistible (build 8)TH_2508-1e-1537.00% (100) PUTATIVE putative anti-sigma-factor antagonist
M. ulcerans Agy99MUL_0605-8e-0936.49% (74) hypothetical protein MUL_0605
M. vanbaalenii PYR-1Mvan_0702-2e-6781.21% (149) anti-sigma-factor antagonist

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_1786|M.smegmatis_MC2_155      ---------MPTISVAKRSSPHSG-SHAPQRAHFTTEQINTATAVVTVHG
TH_2508|M.thermoresistible__bu      -----------MILPVPRPSPGGGEAVTCHAADFATRWVNSATVVIRVDG
MAV_4257|M.avium_104                ------------MSVAQSWQ-------QSRTAQFTARWGLTG-TLITVDG
MMAR_0853|M.marinum_M               ---------MGIAITASSFADRQKNGTFECSGAVVRAHCRHLATIVTIRG
MUL_0605|M.ulcerans_Agy99           ---------MGIAITASSFADRQKNGTFECSGAVVRAHCRHLATIVTIRG
Mflv_0203|M.gilvum_PYR-GCK          MAISEALPPSSTQRVFRPDPTSFELREEHHRATFSACELPPTTVLVTIHG
Mvan_0702|M.vanbaalenii_PYR-1       MSITDPLPASSTQRVFRPDPTSFELREEHHRATFSACELPPSTVLVTIHG
Mb1939|M.bovis_AF2122/97            -MRTVAIGPGAGPSSTRPSSQPSDLHSGLR----AVTECTGSAVVVHVGG
Rv1904|M.tuberculosis_H37Rv         -MRTVAIGPGAGPSSTRPSSQPSDLHSGLR----AVTECTGSAVVVHVGG
MAB_2512|M.abscessus_ATCC_1997      --MSVIDQNASRFAARAKTGVVSLFSSADDTARFTAHWHRPSAVLVRATG
                                                                               .::   *

MSMEG_1786|M.smegmatis_MC2_155      DLDASNAGLLTDYALKALTRNAK---LVLDLSDVAFFGAACFTALHTLNV
TH_2508|M.thermoresistible__bu      ELDAANSPQLVDYALRHAGRIKY---LVADLTGVEFFGIAGFSAAHDING
MAV_4257|M.avium_104                ELDAANADQLAAYVQQSVNRSRR---VILDLRGLNFIGTAGFSALHRINV
MMAR_0853|M.marinum_M               EIDAVNVDQVTERIQHFIHGTNP---VVLDVGDVSHFSPAGISLLAAIDE
MUL_0605|M.ulcerans_Agy99           EIDAVNVDQVTERIQHFIHGTNP---VVLDVGDVSHFSPAGISLLAAIDE
Mflv_0203|M.gilvum_PYR-GCK          EIDATNNMPLAHYIEKRIGDSRK---LIVDLQTVEFFAASGFAALFNVNV
Mvan_0702|M.vanbaalenii_PYR-1       EVDATNSMALACYIEKRLGGARK---LILDLQTVEFFAASGFAALSNINV
Mb1939|M.bovis_AF2122/97            DIDASNEVAWQRLVSKSAAIAIAPGPFVIDIRDLDFMGSCAYAVLAQESV
Rv1904|M.tuberculosis_H37Rv         DIDASNEVAWQRLVSKSAAIAIAPGPFVIDIRDLDFMGSCAYAVLAQESV
MAB_2512|M.abscessus_ATCC_1997      EIDAVNANHLAEYATRYLDGHRT---LVLDLQGLRFFGTDGLVALDRVRR
                                    ::** *         :          .: *:  : .:.            

MSMEG_1786|M.smegmatis_MC2_155      RCAGADAEWVVVPS-KAVTRVLRICDPDSGLTTAPDVVSALSR------K
TH_2508|M.thermoresistible__bu      RCAHAKLTWTLVPS-PAVVRLLQICDPDGTLPLNTTVPDSVWD------N
MAV_4257|M.avium_104                ICSAAQTSWAMAPS-PAVARLLRLCDPDGTLPVTTPKAEPLLEPRRANGD
MMAR_0853|M.marinum_M               ECHAAGAEWTLVAG-PAVVELLG-EDMATMFPVAHSVHEALRNLAEAN-S
MUL_0605|M.ulcerans_Agy99           ECHAAGAEWTLVAG-PAVVELLG-EDMATMFPVAHSVHEALRNLAEAN-S
Mflv_0203|M.gilvum_PYR-GCK          VCHRRGVRWQLLAG-PHVRRLLRVCDPQRELPVTGSSAKYTRT------R
Mvan_0702|M.vanbaalenii_PYR-1       VCARSGVRWTLLAG-THVRRLLRICDPVRELPVAEPAAKYSRT------R
Mb1939|M.bovis_AF2122/97            RCRRRGVNMRLVSNQPIVARTIAACGLRRLIPLYAMVETALAP------P
Rv1904|M.tuberculosis_H37Rv         RCRRRGVNMRLVSNQPIVARTIAACGLRRLIPLYATVETALAP------P
MAB_2512|M.abscessus_ATCC_1997      HCKVQGIDWTVIPG-DAVTKLLTLSGDMAAYPVNDAIPDVWKK-------
                                     *        : ..   * . :   .     .                  

MSMEG_1786|M.smegmatis_MC2_155      SDQR-PLQLVENT-
TH_2508|M.thermoresistible__bu      GGSGGLFQLIPEAG
MAV_4257|M.avium_104                ESPGPLLQLVTKPR
MMAR_0853|M.marinum_M               SRRQLMLSLVRKTA
MUL_0605|M.ulcerans_Agy99           SRRQLMLSLVRKTA
Mflv_0203|M.gilvum_PYR-GCK          PRDRKLLVGGYH--
Mvan_0702|M.vanbaalenii_PYR-1       PSDRKLLVGRHD--
Mb1939|M.bovis_AF2122/97            PSAH----------
Rv1904|M.tuberculosis_H37Rv         PSAH----------
MAB_2512|M.abscessus_ATCC_1997      -----LAQ------