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VPHVPGPPTPPVPDSLICHTARFDTTWTDPATAIVAGKGEVDAANGIRFVDYALRHADQTQWLVIDLSGL SFFSTAGFSALHTLNVQCVGEDIRWALVPGTAVHRVLRICDPDSALPICPDVPSALVAVQEDPPRSFELI TKTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4788 | - | - | 100% (144) | anti-sigma-factor antagonist |
| M. gilvum PYR-GCK | Mflv_3879 | - | 8e-21 | 37.40% (131) | anti-sigma-factor antagonist |
| M. gilvum PYR-GCK | Mflv_0203 | - | 3e-17 | 37.00% (100) | anti-sigma-factor antagonist |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0529c | - | 7e-09 | 35.14% (111) | hypothetical protein Mb0529c |
| M. tuberculosis H37Rv | Rv0516c | - | 7e-09 | 35.14% (111) | hypothetical protein Rv0516c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2512 | - | 1e-16 | 37.50% (104) | hypothetical protein MAB_2512 |
| M. marinum M | MMAR_0853 | - | 2e-06 | 32.26% (93) | hypothetical protein MMAR_0853 |
| M. avium 104 | MAV_4257 | - | 1e-20 | 38.46% (130) | STAS domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_1786 | - | 6e-26 | 50.00% (114) | STAS domain-containing protein |
| M. thermoresistible (build 8) | TH_2508 | - | 1e-29 | 47.06% (119) | PUTATIVE putative anti-sigma-factor antagonist |
| M. ulcerans Agy99 | MUL_0605 | - | 2e-06 | 32.26% (93) | hypothetical protein MUL_0605 |
| M. vanbaalenii PYR-1 | Mvan_1661 | - | 7e-58 | 69.39% (147) | anti-sigma-factor antagonist |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4788|M.gilvum_PYR-GCK ---MPHVPGP---PTPPVPD------SLICHTARFDTTWTDPATAIVAGK
Mvan_1661|M.vanbaalenii_PYR-1 ---MPHVPDQHPAPPAPVSD------NVVCHTARFETRWPQPDTAIVSGL
MSMEG_1786|M.smegmatis_MC2_155 ---MPTISVAK--RSSPHSG------SHAPQRAHFTTEQINTATAVVTVH
TH_2508|M.thermoresistible__bu ----MILPVPR--PSPGGGE------AVTCHAADFATRWVNSATVVIRVD
MAV_4257|M.avium_104 --------------MSVAQS------WQQSRTAQFTARWGLTG-TLITVD
Mb0529c|M.bovis_AF2122/97 MTTTIPTSKSACSVTTRPGN------AAVDYGGAQIRAYLHHLATVVTIR
Rv0516c|M.tuberculosis_H37Rv MTTTIPTSKSACSVTTRPGN------AAVDYGGAQIRAYLHHLATVVTIR
MMAR_0853|M.marinum_M ----MGIAITASSFADRQKN------GTFECSGAVVRAHCRHLATIVTIR
MUL_0605|M.ulcerans_Agy99 ----MGIAITASSFADRQKN------GTFECSGAVVRAHCRHLATIVTIR
MAB_2512|M.abscessus_ATCC_1997 ---MSVIDQNASRFAARAKTGVVSLFSSADDTARFTAHWHRPSAVLVRAT
. .::
Mflv_4788|M.gilvum_PYR-GCK GEVDAANGIRFVDYALRHADQTQWLVIDLSGLSFFSTAGFSALHTLNVQC
Mvan_1661|M.vanbaalenii_PYR-1 GELDAANGIDFVGYALRHSDRAHWLVVDLSGLTFFSTAGFSALHTLNVQC
MSMEG_1786|M.smegmatis_MC2_155 GDLDASNAGLLTDYALKALTRNAKLVLDLSDVAFFGAACFTALHTLNVRC
TH_2508|M.thermoresistible__bu GELDAANSPQLVDYALRHAGRIKYLVADLTGVEFFGIAGFSAAHDINGRC
MAV_4257|M.avium_104 GELDAANADQLAAYVQQSVNRSRRVILDLRGLNFIGTAGFSALHRINVIC
Mb0529c|M.bovis_AF2122/97 GEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDC
Rv0516c|M.tuberculosis_H37Rv GEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDC
MMAR_0853|M.marinum_M GEIDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEEC
MUL_0605|M.ulcerans_Agy99 GEIDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEEC
MAB_2512|M.abscessus_ATCC_1997 GEIDAVNANHLAEYATRYLDGHRTLVLDLQGLRFFGTDGLVALDRVRRHC
*::** * . : :: *: : .:. : : *
Mflv_4788|M.gilvum_PYR-GCK VGEDIRWALVPGTAVHRVLR----ICDPDSALPICPDVPSALVAV-----
Mvan_1661|M.vanbaalenii_PYR-1 VSEDIRWALVPSKAVDRLLR----ICDPDHALPTCADVPTALTVV-----
MSMEG_1786|M.smegmatis_MC2_155 AGADAEWVVVPSKAVTRVLR----ICDPDSGLTTAPDVVSALSRK-----
TH_2508|M.thermoresistible__bu AHAKLTWTLVPSPAVVRLLQ----ICDPDGTLPLNTTVPDSVWDN-----
MAV_4257|M.avium_104 SAAQTSWAMAPSPAVARLLR----LCDPDGTLPVTTPKAEPLLEPRRANG
Mb0529c|M.bovis_AF2122/97 RAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAI-
Rv0516c|M.tuberculosis_H37Rv RAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAI-
MMAR_0853|M.marinum_M HAAGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEAN-
MUL_0605|M.ulcerans_Agy99 HAAGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEAN-
MAB_2512|M.abscessus_ATCC_1997 KVQGIDWTVIPGDAVTKLLT----LSGDMAAYPVNDAIPDVWKKLAQ---
*.: .. ** . * .
Mflv_4788|M.gilvum_PYR-GCK QEDPPRSFELITKTR
Mvan_1661|M.vanbaalenii_PYR-1 QQEPPRSLQLVAESR
MSMEG_1786|M.smegmatis_MC2_155 SDQ--RPLQLVENT-
TH_2508|M.thermoresistible__bu GGSG-GLFQLIPEAG
MAV_4257|M.avium_104 DESPGPLLQLVTKPR
Mb0529c|M.bovis_AF2122/97 DRRRQLVLPLISRSA
Rv0516c|M.tuberculosis_H37Rv DRRRQLVLPLISRSA
MMAR_0853|M.marinum_M SSRRQLMLSLVRKTA
MUL_0605|M.ulcerans_Agy99 SSRRQLMLSLVRKTA
MAB_2512|M.abscessus_ATCC_1997 ---------------