For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTVPPPPGPPWGPPPPYGQPQYGEPQYGQPQYGQPAYGQPYPPPPPLPYPNDPSDPSFGEAPRTNWWAIV SLIFGVIGGVLIALVCGVVGLIKAKQYRSGRGMAIAGIVLAAVWTVGIAVFLVLAANSDRVTATDVKVGD CLAEIPDGERVLTVKTISCEEPHAGEVFAVLMMPDGDFPGQAEVEAYHERCSPELVAYSPQSMLDESVQL YVLYPTAETWDNGDRAVTCIATLDPPRTGSIRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0183 | - | - | 100% (243) | hypothetical protein Mflv_0183 |
| M. gilvum PYR-GCK | Mflv_2210 | - | 3e-11 | 33.11% (148) | hypothetical protein Mflv_2210 |
| M. gilvum PYR-GCK | Mflv_2044 | - | 4e-08 | 34.33% (134) | integral membrane protein-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1265c | - | 2e-12 | 35.81% (148) | hypothetical protein Mb1265c |
| M. tuberculosis H37Rv | Rv1233c | - | 8e-13 | 36.84% (133) | hypothetical protein Rv1233c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3781 | - | 7e-40 | 37.21% (258) | hypothetical protein MAB_3781 |
| M. marinum M | MMAR_4208 | - | 2e-13 | 36.11% (144) | proline and glycine rich transmembrane protein |
| M. avium 104 | MAV_1372 | - | 8e-15 | 41.54% (130) | hypothetical protein MAV_1372 |
| M. smegmatis MC2 155 | MSMEG_0823 | - | 7e-45 | 42.19% (237) | hypothetical protein MSMEG_0823 |
| M. thermoresistible (build 8) | TH_4444 | - | 4e-24 | 45.37% (108) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1750 | - | 4e-09 | 45.61% (57) | proline and glycine rich transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_0722 | - | 8e-91 | 73.04% (204) | hypothetical protein Mvan_0722 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0183|M.gilvum_PYR-GCK ---MTVPPPPGPPWGPPPPYGQPQYGEPQYGQPQYGQP------------
Mvan_0722|M.vanbaalenii_PYR-1 ---MTVPPP-----------------------------------------
MSMEG_0823|M.smegmatis_MC2_155 ---MTTPPGPPPPPYG----------------------------------
TH_4444|M.thermoresistible__bu --------------------------------------------------
MAB_3781|M.abscessus_ATCC_1997 ---MTQPPAGPPPPDPGQPEFPPYPTPTSSGYPPVEPSPGAYPPIPPAAG
Mb1265c|M.bovis_AF2122/97 ---MTAPSGSSGESAHDAAGGPPPVGERPPEQPIA------------DAP
Rv1233c|M.tuberculosis_H37Rv ---MTAPSGSSGESAHDAAGGPPPVGERPPEQPIA------------DAP
MMAR_4208|M.marinum_M ---MTAPGGSFDEGAHDGAASPPP-GEQPSEQPFSPPP---------DAP
MAV_1372|M.avium_104 MNTMTAPGAGFGESAQHDHHGDQAHGDKPNDDATS-------------AP
MUL_1750|M.ulcerans_Agy99 ---MSQPPENPGNQADPQDGDQSTPGYPPP-------------------P
Mflv_0183|M.gilvum_PYR-GCK -----------AYGQPYPPPPPLP--------YPNDPSDPSFGEAPRTNW
Mvan_0722|M.vanbaalenii_PYR-1 ----------------YPPPPPLP--------YQGGPGQPYYPPPRRTNW
MSMEG_0823|M.smegmatis_MC2_155 -------------AHGYPPPPPLP--------YTNGTGPIPQPPKKPRRV
TH_4444|M.thermoresistible__bu --------------------------------------------------
MAB_3781|M.abscessus_ATCC_1997 PGAEPYPPYPQANPAGYPPPPGYPPPASPYGAYPAAGAYPPVESARGTNG
Mb1265c|M.bovis_AF2122/97 WAPP-ASSPMADHPPPAYPPSGYPP------AYQPGYPTDYPPPMP----
Rv1233c|M.tuberculosis_H37Rv WAPP-ASSPMANHPPPAYPPSGYPP------AYQPGYPTGYPPPMP----
MMAR_4208|M.marinum_M WAAPEAASPADDYPAPSYPPPAYPPEPVGPGGYPPDYATGYPP--P----
MAV_1372|M.avium_104 HAQPAPWEPPAGSVPPPYPPPGYPA------DYPPGYPPPYPPPAPS---
MUL_1750|M.ulcerans_Agy99 NYGTPPPPPPPGYGAPPAGPPGYGAP-----PPPPGYGTPPPPPPPGYGQ
Mflv_0183|M.gilvum_PYR-GCK WAIVSLIFGVIGGVL--IALVCGVVGLIKAKQY-----RSGRGMAIAGIV
Mvan_0722|M.vanbaalenii_PYR-1 WAVVSLIFGVIGGVL--ISLVCGIVGLAKVKQY-----QSGRGMAIAGIV
MSMEG_0823|M.smegmatis_MC2_155 WVLVAVVVAVL---------------------------------------
TH_4444|M.thermoresistible__bu --------------------------------------------------
MAB_3781|M.abscessus_ATCC_1997 FAIASLILGIVPICAGIFGVVFGFISLNQIKRTG----QNGRGMAIAGIV
Mb1265c|M.bovis_AF2122/97 -PGGYAPPGYPPPGTSSAGYGDIPYPPMPPP-------YGGSP-------
Rv1233c|M.tuberculosis_H37Rv -PGGYAPPGYPPPGTSSAGYGDIPYPPMPPP-------YGGSP-------
MMAR_4208|M.marinum_M -PG-YPPPGYPPYGAAAGEYGGTPYPPPPPPPAPMAAPYGAPPPNYPPP-
MAV_1372|M.avium_104 -PVPPPPPGYGPP--PPPGYGPPGYPGGYYP---------GPD-------
MUL_1750|M.ulcerans_Agy99 APGGYAPPGYNPPPPPPPGYGPPPAGYSTQPG------FGGPAKPPFSVG
Mflv_0183|M.gilvum_PYR-GCK LAAVWTVGIAVFLVL-------------AANSDRVT---------ATDVK
Mvan_0722|M.vanbaalenii_PYR-1 LSVLWSIAIVAIIIA-------------AVNDDTVN---------ATNVK
MSMEG_0823|M.smegmatis_MC2_155 --AMLVAGAAVALYY-------------VTEKDSTE---------ASQVK
TH_4444|M.thermoresistible__bu ---------------------------------------------VADVE
MAB_3781|M.abscessus_ATCC_1997 LGFIWMIVLAVVVAVGAGNSAKRDESGHVTQSGDMD---------VTKLR
Mb1265c|M.bovis_AF2122/97 -------------------------------GGYYP----------EPGY
Rv1233c|M.tuberculosis_H37Rv -------------------------------GGYYP----------EPGY
MMAR_4208|M.marinum_M ----------------------------SYPGGYYP----------PPDP
MAV_1372|M.avium_104 ------------------------------YGGYPP----------QPPL
MUL_1750|M.ulcerans_Agy99 EAISWAWNRFTQNAMALVVPIVIYGLILSAVGGVMVGLFFAFSDRTSTTY
Mflv_0183|M.gilvum_PYR-GCK VGDCLAEIPDGER-------------------------------------
Mvan_0722|M.vanbaalenii_PYR-1 LGDCLAEIPGGER-------------------------------------
MSMEG_0823|M.smegmatis_MC2_155 VGDCLAEIPDSSR-------------------------------------
TH_4444|M.thermoresistible__bu VGHCVAEVPDSSR-------------------------------------
MAB_3781|M.abscessus_ATCC_1997 VGDCVADLGEKSY-------------------------------------
Mb1265c|M.bovis_AF2122/97 LDGYGPSQPGMNT-------------------------------------
Rv1233c|M.tuberculosis_H37Rv LDGYGPSQPGMNT-------------------------------------
MMAR_4208|M.marinum_M MAGYGPALPGMNT-------------------------------------
MAV_1372|M.avium_104 LGG----QPGTNG-------------------------------------
MUL_1750|M.ulcerans_Agy99 TDAYGNTSETVNMTMSPLASIVMFIGYLAVFAVVLFMHAGITTGCLDIAD
.
Mflv_0183|M.gilvum_PYR-GCK --------------VLTVKTISCEEPHAGEVFAVLMMPDGDFPGQAEVEA
Mvan_0722|M.vanbaalenii_PYR-1 --------------VASVKTVSCDQPHAGEVFAVLTMRDGDFPGQAAVEA
MSMEG_0823|M.smegmatis_MC2_155 --------------VLYVETVACDQPHKGEVFAVMQMPDGDFPGEGAVLE
TH_4444|M.thermoresistible__bu --------------VTTLAVVDCTEQHRGEVFAVIPIPDGAYPPASVLEE
MAB_3781|M.abscessus_ATCC_1997 --------------YTTTKAIPCAQPHKAEVYAVLPLSGSSLPSQSVLDE
Mb1265c|M.bovis_AF2122/97 --------------MALVSLISALVGVLCCIGSIVGIVFGAIA-------
Rv1233c|M.tuberculosis_H37Rv --------------MALVSLISALVGVLCCIGSIVGIVFGAIA-------
MMAR_4208|M.marinum_M --------------MAIVALVSSLVGVFCCIGSVVAIVVGTIA-------
MAV_1372|M.avium_104 --------------LAIASLIASFTGLLCGIGSVVAIVLGAIA-------
MUL_1750|M.ulcerans_Agy99 GKPVTIGSFFKPRNLGMVILTGLLVIVLTAIGSVLCIVPGLIFGFLAQFA
: ::: : .
Mflv_0183|M.gilvum_PYR-GCK Y---HERCSPELVAYSPQSMLD---------ESVQLYVLYPTAETWDNGD
Mvan_0722|M.vanbaalenii_PYR-1 Y---HEKCSPELQRYSPESMTD---------DSVQLYVLYPTAETWEDGD
MSMEG_0823|M.smegmatis_MC2_155 F---TEKCGPALKEYAPAAADD---------KAIRAMVLYPTADSWQRGD
TH_4444|M.thermoresistible__bu H---QRRCRPALDGYATPAPD----------RPVEVFVLAPSEESWERGH
MAB_3781|M.abscessus_ATCC_1997 KG--NEECGAELESYAPSAFDD---------DSVQITYLYPTKRSWAQGD
Mb1265c|M.bovis_AF2122/97 -----------INQIKQTREEG--------------YGLAVAGIVIGIAT
Rv1233c|M.tuberculosis_H37Rv -----------INQIKQTREEG--------------YGLAVAGIVIGIAT
MMAR_4208|M.marinum_M -----------INQIKQTREDG--------------YGLAVAGIVIAVAT
MAV_1372|M.avium_104 -----------LDQIKRTRQDG--------------FGLAVAGIVIGIAT
MUL_1750|M.ulcerans_Agy99 IIAAVDRSLSPIDSIKSSCATVRAELGNTALSWLVQYAVVLAGELLCFVG
: : :
Mflv_0183|M.gilvum_PYR-GCK RAVTCIATLDPPRTGSIRG-------------------------------
Mvan_0722|M.vanbaalenii_PYR-1 RTVTCIATLDPPRTGSLKG-------------------------------
MSMEG_0823|M.smegmatis_MC2_155 RTVTCIATSENSRTGKIG--------------------------------
TH_4444|M.thermoresistible__bu RTVTCIAITDNYRTDTMR--------------------------------
MAB_3781|M.abscessus_ATCC_1997 RAIACVATFDTQRTASIKGK------------------------------
Mb1265c|M.bovis_AF2122/97 LLVYMIAGIFAIP-------------------------------------
Rv1233c|M.tuberculosis_H37Rv LLVYMIAGIFAIP-------------------------------------
MMAR_4208|M.marinum_M LLIYLVVGIFSIPSH-----------------------------------
MAV_1372|M.avium_104 LVVTLVVVLFALHTH-----------------------------------
MUL_1750|M.ulcerans_Agy99 MLVGVPVASLIQTYTWRKLSGGQVVELSQPGPPAGLPPGPPPGAPPGPQF
: .
Mflv_0183|M.gilvum_PYR-GCK -
Mvan_0722|M.vanbaalenii_PYR-1 -
MSMEG_0823|M.smegmatis_MC2_155 -
TH_4444|M.thermoresistible__bu -
MAB_3781|M.abscessus_ATCC_1997 -
Mb1265c|M.bovis_AF2122/97 -
Rv1233c|M.tuberculosis_H37Rv -
MMAR_4208|M.marinum_M -
MAV_1372|M.avium_104 -
MUL_1750|M.ulcerans_Agy99 G