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TTPPGPPPPPYGAHGYPPPPPLPYTNGTGPIPQPPKKPRRVWVLVAVVVAVLAMLVAGAAVALYYVTEKD STEASQVKVGDCLAEIPDSSRVLYVETVACDQPHKGEVFAVMQMPDGDFPGEGAVLEFTEKCGPALKEYA PAAADDKAIRAMVLYPTADSWQRGDRTVTCIATSENSRTGKIG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0823 | - | - | 100% (184) | hypothetical protein MSMEG_0823 |
| M. smegmatis MC2 155 | MSMEG_0047 | - | 1e-06 | 32.67% (101) | hypothetical protein MSMEG_0047 |
| M. smegmatis MC2 155 | MSMEG_5916 | - | 4e-05 | 44.19% (43) | hypothetical protein MSMEG_5916 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1107 | pra | 6e-06 | 55.26% (38) | proline-rich antigen |
| M. gilvum PYR-GCK | Mflv_0183 | - | 4e-45 | 42.19% (237) | hypothetical protein Mflv_0183 |
| M. tuberculosis H37Rv | Rv1078 | pra | 7e-06 | 55.26% (38) | proline-rich antigen |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3781 | - | 7e-26 | 30.49% (223) | hypothetical protein MAB_3781 |
| M. marinum M | MMAR_4389 | pra | 1e-06 | 52.78% (36) | proline-rich antigen, Pra |
| M. avium 104 | MAV_3282 | - | 2e-05 | 36.36% (77) | hypothetical protein MAV_3282 |
| M. thermoresistible (build 8) | TH_4444 | - | 6e-25 | 48.57% (105) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0202 | pra | 2e-07 | 60.61% (33) | proline-rich antigen Pra-like protein |
| M. vanbaalenii PYR-1 | Mvan_0722 | - | 2e-43 | 41.63% (209) | hypothetical protein Mvan_0722 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0823|M.smegmatis_MC2_155 -------------------------------------MTTPPGPPPPPYG
TH_4444|M.thermoresistible__bu --------------------------------------------------
Mflv_0183|M.gilvum_PYR-GCK -------------------------------------MTVPPPPGPPWGP
Mvan_0722|M.vanbaalenii_PYR-1 -------------------------------------MTVPPP-------
MAB_3781|M.abscessus_ATCC_1997 -------------------------------------MTQPPAGPPPPDP
Mb1107|M.bovis_AF2122/97 ------------------------------------MTEQPPPGGSYPPP
Rv1078|M.tuberculosis_H37Rv ------------------------------------MTEQPPPGGSYPPP
MMAR_4389|M.marinum_M ------------------------------------MTDQPPPGGSYPPP
MUL_0202|M.ulcerans_Agy99 ------------------------------------MTDQPPPGGSYPPP
MAV_3282|M.avium_104 MTPTPSLQRRVTLVVLALLTVLLVVLGVTIDVTMGVLARRNLHDRLLAAT
MSMEG_0823|M.smegmatis_MC2_155 -----------------------------------------------AHG
TH_4444|M.thermoresistible__bu --------------------------------------------------
Mflv_0183|M.gilvum_PYR-GCK PPPYGQPQYGEPQYGQPQYGQP-----------------------AYGQP
Mvan_0722|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3781|M.abscessus_ATCC_1997 GQPEFPPYPTPTSSGYPPVEPSPGAYPPIPPAAGPGAEPYPPYPQANPAG
Mb1107|M.bovis_AF2122/97 PPPPGPSGGHEP--------PPAAP--------------------PGGSG
Rv1078|M.tuberculosis_H37Rv PPPPGPSGGHEP--------PPAAP--------------------PGGSG
MMAR_4389|M.marinum_M PPPPGSSGGSEPPAGGYQAPPPPSA--------------------PSGGG
MUL_0202|M.ulcerans_Agy99 PPPPGSSGGSEPPAGGYQAPPPPSA--------------------PSGGG
MAV_3282|M.avium_104 SRADALSAAHTAPDLLAAELNGGGIRALVVTADGQAYGDRVISPDLAEGP
MSMEG_0823|M.smegmatis_MC2_155 YPPPPPLP--------YTNGTGPIPQPPKK---------------PRRVW
TH_4444|M.thermoresistible__bu --------------------------------------------------
Mflv_0183|M.gilvum_PYR-GCK YPPPPPLP--------YPNDPSDPSFGEAP---------------RTNWW
Mvan_0722|M.vanbaalenii_PYR-1 YPPPPPLP--------YQGGPGQPYYPPPR---------------RTNWW
MAB_3781|M.abscessus_ATCC_1997 YPPPPGYPPPASPYGAYPAAGAYPPVESAR---------------GTNGF
Mb1107|M.bovis_AF2122/97 YAPPPPPS----------SGSGYPPPPPPP-----------------GGG
Rv1078|M.tuberculosis_H37Rv YAPPPPPS----------SGSGYPPPPPPP-----------------GGG
MMAR_4389|M.marinum_M YPPPPPPPS--------PSTSGYPPPPPPPSAPGGSAYPPPPPPPPLEGG
MUL_0202|M.ulcerans_Agy99 YPPPPPPPP--------PSTSGYPPPPPPP---------------PLEGG
MAV_3282|M.avium_104 VEPPPPYPPPLPP---PYPPPAYPPPYPPP--------------YPPPPG
MSMEG_0823|M.smegmatis_MC2_155 VLVAVVVAVLA---------------------------MLVAGAAVALYY
TH_4444|M.thermoresistible__bu --------------------------------------------------
Mflv_0183|M.gilvum_PYR-GCK AIVSLIFGVIGGVL--IALVCGVVGLIKAKQY-RSGRGMAIAGIVLAAVW
Mvan_0722|M.vanbaalenii_PYR-1 AVVSLIFGVIGGVL--ISLVCGIVGLAKVKQY-QSGRGMAIAGIVLSVLW
MAB_3781|M.abscessus_ATCC_1997 AIASLILGIVPICAGIFGVVFGFISLNQIKRTGQNGRGMAIAGIVLGFIW
Mb1107|M.bovis_AF2122/97 AYPPPPPSAGGYAPPPPGPAIRTMPTESYTPWITRVLAAFIDWAPYVVLV
Rv1078|M.tuberculosis_H37Rv AYPPPPPSAGGYAPPPPGPAIRTMPTESYTPWITRVLAAFIDWAPYVVLV
MMAR_4389|M.marinum_M YPPPPPPSAGGYAPPPPGPAIRALPAESYTPWITRVLAALIDFAPYVVVT
MUL_0202|M.ulcerans_Agy99 YPPPPPPSAGGYAPPPPGPAIRALPAESYTPWITRVLAALIDFAPYVVVT
MAV_3282|M.avium_104 PLPDTTATAVVHPLSGGARLILVADTTQTTQVTRQLRGLMIAAGIVTLLI
MSMEG_0823|M.smegmatis_MC2_155 ---------------------------------------VTEKDSTEASQ
TH_4444|M.thermoresistible__bu -----------------------------------------------VAD
Mflv_0183|M.gilvum_PYR-GCK TVGIAVFLVL-----------------------------AANSDRVTATD
Mvan_0722|M.vanbaalenii_PYR-1 SIAIVAIIIA-----------------------------AVNDDTVNATN
MAB_3781|M.abscessus_ATCC_1997 MIVLAVVVAVGAGNSAKRDESGH----------------VTQSGDMDVTK
Mb1107|M.bovis_AF2122/97 GIGWVIMLVT-----------------------------QTSSCVTSISE
Rv1078|M.tuberculosis_H37Rv GIGWVIMLVT-----------------------------QTSSCVTSISE
MMAR_4389|M.marinum_M GIGWLIMMVT-----------------------------TTSSCVTDISQ
MUL_0202|M.ulcerans_Agy99 GIGWLIMMVT-----------------------------TTPSCVTDISQ
MAV_3282|M.avium_104 AALLLIAVSRAALRPLDRLTALANAITTGDRGRRLRPHRADTELGRAASA
:
MSMEG_0823|M.smegmatis_MC2_155 VKVG-DCLAEIPDSSRVLYVETVACDQPHKGEVFAVMQMPDGDFPGEGAV
TH_4444|M.thermoresistible__bu VEVG-HCVAEVPDSSRVTTLAVVDCTEQHRGEVFAVIPIPDGAYPPASVL
Mflv_0183|M.gilvum_PYR-GCK VKVG-DCLAEIPDGERVLTVKTISCEEPHAGEVFAVLMMPDGDFPGQAEV
Mvan_0722|M.vanbaalenii_PYR-1 VKLG-DCLAEIPGGERVASVKTVSCDQPHAGEVFAVLTMRDGDFPGQAAV
MAB_3781|M.abscessus_ATCC_1997 LRVG-DCVADLGEKSYYTTTKAIPCAQPHKAEVYAVLPLSGSSLPSQSVL
Mb1107|M.bovis_AF2122/97 YDVGQFCVSQPSMIGQLVQWLLSVGGLAYLVWNYGYRQGTTGSSIGKSVL
Rv1078|M.tuberculosis_H37Rv YDVGQFCVSQPSMIGQLVQWLLSVGGLAYLVWNYGYRQGTIGSSIGKSVL
MMAR_4389|M.marinum_M YDIGQYCVSQPSMIGQLAQWLLSLVGLAYLVWDYGYRQGTTGSSIGKSIM
MUL_0202|M.ulcerans_Agy99 YDIGQYCVSQPSMIGQLAQWLLSLVGLAYLVWDYGYRQGTTGSSIGKSIM
MAV_3282|M.avium_104 FDTMLDALEMSERRAQQAAEAAQRAETATRRFLVDAAHELRTPIAGMQVA
.:
MSMEG_0823|M.smegmatis_MC2_155 LEF-TEKCGPALKE--------YAPAAADDKAIRAMVLYPTA----DSWQ
TH_4444|M.thermoresistible__bu EEH-QRRCRPALDG--------YATPAPD-RPVEVFVLAPSE----ESWE
Mflv_0183|M.gilvum_PYR-GCK EAY-HERCSPELVA--------YSPQSMLDESVQLYVLYPTA----ETWD
Mvan_0722|M.vanbaalenii_PYR-1 EAY-HEKCSPELQR--------YSPESMTDDSVQLYVLYPTA----ETWE
MAB_3781|M.abscessus_ATCC_1997 DEKGNEECGAELES--------YAPSAFDDDSVQITYLYPTK----RSWA
Mb1107|M.bovis_AF2122/97 KFKVVSETTGQPIG--------FGMSVVRQLAHFIDAIICFVGFLFPLWD
Rv1078|M.tuberculosis_H37Rv KFKVVSETTGQPIG--------FGMSVVRQLAHFIDAIICFVGFLFPLWD
MMAR_4389|M.marinum_M KFKVVSETTGEPLG--------FGMSVVRQLAHIVDAIICYIGFLFPLWD
MUL_0202|M.ulcerans_Agy99 KFKVVSETTGEPLG--------FGMSVVRQLAHIVDAVICYIGFLFPLWD
MAV_3282|M.avium_104 AEQLAHGASEHPDDGQYRRAGLLLSDARRAGRLVNDMLDLSRIDAGLPLE
:
MSMEG_0823|M.smegmatis_MC2_155 RGDRTVTCIATSENSRTGKIG-----------------------------
TH_4444|M.thermoresistible__bu RGHRTVTCIAITDNYRTDTMR-----------------------------
Mflv_0183|M.gilvum_PYR-GCK NGDRAVTCIATLDPPRTGSIRG----------------------------
Mvan_0722|M.vanbaalenii_PYR-1 DGDRTVTCIATLDPPRTGSLKG----------------------------
MAB_3781|M.abscessus_ATCC_1997 QGDRAIACVATFDTQRTASIKGK---------------------------
Mb1107|M.bovis_AF2122/97 AKRQTLADKIMTTVCVPI--------------------------------
Rv1078|M.tuberculosis_H37Rv AKRQTLADKIMTTVCVPI--------------------------------
MMAR_4389|M.marinum_M AKRQTLADKIMTTVCLPL--------------------------------
MUL_0202|M.ulcerans_Agy99 AKRQTLADKIMTTVCLPL--------------------------------
MAV_3282|M.avium_104 LHDVDVAAVLRDEADRAALLAPQIGVRRTGLTALNVRADATRLSQIVSNL
:: .
MSMEG_0823|M.smegmatis_MC2_155 --------------------------------------------------
TH_4444|M.thermoresistible__bu --------------------------------------------------
Mflv_0183|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0722|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3781|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 --------------------------------------------------
Rv1078|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4389|M.marinum_M --------------------------------------------------
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
MAV_3282|M.avium_104 LDNARRYTPAGGAIEIDLRAGDGAAEITVTDTGPGIPDDEREHIFDRLVR
MSMEG_0823|M.smegmatis_MC2_155 --------------------------------------------------
TH_4444|M.thermoresistible__bu --------------------------------------------------
Mflv_0183|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0722|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3781|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 --------------------------------------------------
Rv1078|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4389|M.marinum_M --------------------------------------------------
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
MAV_3282|M.avium_104 LDAGRARDHGGAGLGLAIARALARAHGGDLVCLPHQGGARFRLTLPRATT
MSMEG_0823|M.smegmatis_MC2_155 -
TH_4444|M.thermoresistible__bu -
Mflv_0183|M.gilvum_PYR-GCK -
Mvan_0722|M.vanbaalenii_PYR-1 -
MAB_3781|M.abscessus_ATCC_1997 -
Mb1107|M.bovis_AF2122/97 -
Rv1078|M.tuberculosis_H37Rv -
MMAR_4389|M.marinum_M -
MUL_0202|M.ulcerans_Agy99 -
MAV_3282|M.avium_104 Q