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MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADEVSARIAALFGGFGLEYQAISAQVA AYHQRFVQALSTGAGAYASAEAAAAEQIVLGVINAPTQALLGRPLIGDGANATTPGGAGGAGGLLFGNGG AGAAGAPGQAGGPGGPAGLWGNGGPGGAGGSGGGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGL IWGGGGAGGVGGAGGGTGGAGGRAELLFGAGGAGGAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAG GAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGGTGGAGGDGVLGGV GGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVGVGGTGGQGGAGGMGGSGADNASGIGADGGAGGTG GNAGAGGAGGAAGTGGTGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDATATGATGGTGFSGGAGGAGGAG GNTGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIGGAGGTGGAGGTGGTGGAAGAGGAGGAVGTGGT GGVVGDVGNAGIGGTGGKGGAGGTGFAGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADN PTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVGGAGGAGAAAAAGSSATG GAGFAGGAGGEGGAGGNSGVGGTNGSGGAGGAGGKGGTGGAGGSGADNPTGAGFAGGAGGTGGAAGAGGA GGATGTGGTGGVVGATGSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGDGGSAGAGGINGAGGA GGDGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDN NFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGAGGG GGFGGAAGKAGGGGNGGVGGDGGEGATGLGLDLSGFAGGQGGQGGAGGNAGAGGINGAGGTGGTGGAGGD GAPATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGGAGDAGADGDPSIDGGQG GAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGAGGLANTGGT AGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGGAGGNAGAGGINGAGGTGGTGGAGGDGAPAT LIGGPDGGDGGQGGGAGFGSGVAGAAGAGGNGGKGGDGGTGGTGGTNFAGGQGGAGGRGGAGGNGANGVG DNAAGGDGGNGGAGGLGGGGGTGGTNGNGGLGGGGGNGGAGGAGGTPTGSGTEGTGGDGGDAGAGGNGGS ATGVGNGGNGGDGGNGGDGGNGAPGGFGGGAGAGGLGGSGAGGGTDGDDGNGGSPGTDGS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3538 | PE_PGRS54 | - | 100% (1460) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb3541 | PE_PGRS55 | 0.0 | 50.47% (1811) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb3543 | PE_PGRS57 | 0.0 | 74.56% (1022) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_5091 | - | 0.0 | 50.36% (824) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 0.0 | 71.71% (1697) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 9e-14 | 41.76% (91) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 5e-59 | 33.08% (520) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_1594 | - | 0.0 | 55.77% (1594) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 1e-28 | 48.81% (168) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-171 | 41.94% (1061) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 2e-51 | 41.53% (301) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 53.54% (1117) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 0.0 | 47.56% (862) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb3538|M.bovis_AF2122/97 --------------------------------MSFVLIAPEFVTAAAGD- Rv3508|M.tuberculosis_H37Rv --------------------------------MSFVLIAPEFVTAAAGD- MMAR_1594|M.marinum_M --------------------------------MSYMSISPEIVSSAAGE- MUL_4367|M.ulcerans_Agy99 --------------------------------MSFVSVGPGLLEAAARD- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------MSIIDF MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------------------------------MNIVLGVSMAP Mb3538|M.bovis_AF2122/97 -LTNLGSSISAANASAASATTQVLA-----AGADEVSARIAALFGGFGLE Rv3508|M.tuberculosis_H37Rv -LTNLGSSISAANASAASATTQVLA-----AGADEVSARIAALFGGFGLE MMAR_1594|M.marinum_M -LANIGSTVSAANAAAAVATTELLA-----AGSDEVSTRIAALFGANGVE MUL_4367|M.ulcerans_Agy99 -LAGLGAGLREANLAAAGATVGVLP-----AAGDEVSAAIAELFGGFGRE Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------MVTFGGGA-- Mvan_1264|M.vanbaalenii_PYR-1 ----MMFLAPPGGPGPISAAIQLTS-----TGSEATEPWYVVSFGGSG-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ILNLFRDPVEAASYVADPEAALANAG---------LSAVSAAQVGAVMPV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 SSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREG Mb3538|M.bovis_AF2122/97 YQAISAQVAAYHQRFVQALSTGAGAYASAEAA------AAEQIVLGVINA Rv3508|M.tuberculosis_H37Rv YQAISAQVAAYHQRFVQALSTGAGAYASAEAA------AAEQIVLGVINA MMAR_1594|M.marinum_M YQAISAQIASFHDRFVAALNTGTSSYVWAEAT------NVEQNLLNAVNA MUL_4367|M.ulcerans_Agy99 YQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQELEQQALGVVNA Mflv_5091|M.gilvum_PYR-GCK ----TPTPTSLGAAAVDLSGTSCG-------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----APTPNNLAASLVDLSGTSCG-------------------------- MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VAESVASNYGYQSQWVNTGNPIHDLSGNLQN------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AADAGLQLSSIGVTWTDQLEAAALRDALAARR------------------ Mb3538|M.bovis_AF2122/97 PTQ----------------------------------------------- Rv3508|M.tuberculosis_H37Rv PTQ----------------------------------------------- MMAR_1594|M.marinum_M PVQ----------------------------------------------- MUL_4367|M.ulcerans_Agy99 PSM----------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ----------------------------------ALLGRPLIGDGAN-AT Rv3508|M.tuberculosis_H37Rv ----------------------------------ALLGRPLIGDGAN-AT MMAR_1594|M.marinum_M ----------------------------------TLLGRPLIGNGAN-AT MUL_4367|M.ulcerans_Agy99 ----------------------------------ALFGRPSIGNGVDGVA Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------LICNGQD--- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------LICNGQD--- MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN-GT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------YYAAQPDGPSILS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------IDNVMLVSAFLAA Mb3538|M.bovis_AF2122/97 TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG Rv3508|M.tuberculosis_H37Rv TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG MMAR_1594|M.marinum_M TPGGAGGDGGLLYGSGGNGA-AGAPGQAGGAGGSAGLWGNGGSGGSGGIG MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGGVG Mflv_5091|M.gilvum_PYR-GCK ---GTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGLFG--GNGGNGGNG Mvan_1264|M.vanbaalenii_PYR-1 ---GTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGLFG--GNGGNGGNG MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAG TH_3810|M.thermoresistible__bu ------------------------VDGDGGSGGRTGLFSKLSRGGD---- MAB_4284c|M.abscessus_ATCC_199 PSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAES Mb3538|M.bovis_AF2122/97 GGTGGAGGAGGWLFGVGGAGGVGGAGGG---------------------- Rv3508|M.tuberculosis_H37Rv GGTGGAGGAGGWLFGVGGAGGVGGAGGG---------------------- MMAR_1594|M.marinum_M GGTGGNGGSGGWLLGRGGIGGAGGTGGGSGGSGGGAWLFGDGGAGGMGGT MUL_4367|M.ulcerans_Agy99 -AAGMTGGS----------------------------------------- Mflv_5091|M.gilvum_PYR-GCK LGGGN--------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 LGSGD--------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 LD------------------------------------------------ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 FG------------------------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 YG------------------------------------------------ Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GGSGGGFGGTGGHGGLLYGNGGAGGAGATGQTGGSGGWAALWGRGGAGGA MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GGDNGGFAGGDGGHGGLLCGAGGDGGLGGGDGGNAGWLLGFGGHGGAGGD MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -----------------------------TGGAGGPGGLIWGGGGAGGVG Rv3508|M.tuberculosis_H37Rv -----------------------------TGGAGGPGGLIWGGGGAGGVG MMAR_1594|M.marinum_M GGFAGGEGGNGGWLLGFGGHGGTGGIGGGTGGAGGAGGLVMGFGGHGGTG MUL_4367|M.ulcerans_Agy99 ------------------------------GGAGGGGGWLWGAGGSGGAA Mflv_5091|M.gilvum_PYR-GCK ------------------------------GGNGGNAGAFALFGN----- Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------GGNGGDAGLFSLFGR----- MSMEG_0868|M.smegmatis_MC2_155 ------------------------------GGNGGSGGLLMGIGGAGGAG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GAGGGTGGAGGRAELLFGAGGAGGAGGAGTDGGPG--------------- Rv3508|M.tuberculosis_H37Rv GAGGGTGGAGGRAELLFGAGGAGGAG---TDGGPG--------------- MMAR_1594|M.marinum_M GIGGGAGGAGGQAALLFGHGGGGGAGGVGTAGGAGGAGGDGGNPGWLLGR MUL_4367|M.ulcerans_Agy99 GAGG---------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GVG----------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -----------------ATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAG Rv3508|M.tuberculosis_H37Rv -----------------ATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAG MMAR_1594|M.marinum_M AGSGGDGGAGGAATTVGATGGVGGHGGAGGRGGVLMGGGAGGDGGAGGAG MUL_4367|M.ulcerans_Agy99 ---------------------------SGGSGGWLWG----NAGQTAGAG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ----------------------------------ADGTSAHVDGGTGGTG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GAGSDGGALGG---TGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQG Rv3508|M.tuberculosis_H37Rv GAGSDGGALGG---TGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQG MMAR_1594|M.marinum_M ADGSNGVGDGGNGATGGGGGVGGDGGAGGQAALLFGCGGTGGHAGAGGAG MUL_4367|M.ulcerans_Agy99 --------------VGGAGGAGGAGDAGDQGVSGVAPGEAGAVGFAGGAG Mflv_5091|M.gilvum_PYR-GCK ---------------GGNGGNGGVGVVG-------------ATGAVGAPG Mvan_1264|M.vanbaalenii_PYR-1 ---------------GGNGGNGGVGIAG-------------ATGAVGAPG MSMEG_0868|M.smegmatis_MC2_155 ---------------GTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAA TH_3810|M.thermoresistible__bu ---------------GGDGGLGGNGGHG---------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------DLQFGNRDTTAIG---------DGAVAVGGSNSGP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------DAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAP Mb3538|M.bovis_AF2122/97 GTGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVG Rv3508|M.tuberculosis_H37Rv GTGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVG MMAR_1594|M.marinum_M GGGGTGADSLTG-IGGAGGDGGIGGASGQAGAG-GAGNLFSHNGSRGHAG MUL_4367|M.ulcerans_Agy99 GAGGAGGNGVGGGVNGAGGAGGAG-------------------------G Mflv_5091|M.gilvum_PYR-GCK VAGATGATGVTSGVVGGNGEDAVG-------------------------- Mvan_1264|M.vanbaalenii_PYR-1 VAGATGATGVTSNVTGGNGADAVG-------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGDGGNGGFGYVLIAGPNVTVG-----------------------SET TH_3810|M.thermoresistible__bu -----GGTGIISLLSLAG-------------------------------- MAB_4284c|M.abscessus_ATCC_199 IASGQGSTAVNGDVRDSNIINADHG-----------------------SN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 LKQVLQTTTFLDVSVAEEPETALAR------------------------- Mb3538|M.bovis_AF2122/97 VGGTGGQGGAG--------------------------------------- Rv3508|M.tuberculosis_H37Rv VGGTGGQGGAGGAGAAGADAPASTGLTGGTGFAGGAGGVGGQGGNAIAGG MMAR_1594|M.marinum_M IGGDGGDGGTGGTGGEGTDAAAGSGLTGGTGYAGGTGGTGGAGGNSGLGG MUL_4367|M.ulcerans_Agy99 VGGGGGAGASG--------------------------------------- Mflv_5091|M.gilvum_PYR-GCK YGATGAAGAAG--------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 YGATGAAGAAG--------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 RGGTGGAGGTG--------------------------------------- TH_3810|M.thermoresistible__bu ---NGGNGGNG--------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VGVDQSQTRVG--------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -GAALAAANAP--------------------------------------- Mb3538|M.bovis_AF2122/97 -----------------GMGGSGADNASGIGADGGAGGTGGNAGAGGAGG Rv3508|M.tuberculosis_H37Rv INGSGGAGGTGGQGGAGGMGGSGADNASGIGADGGAGGTGGNAGAGGAGG MMAR_1594|M.marinum_M TNGSGGHGGTGGTGGTGGTGGSGADNTTGIGGDGGQGGTGGDAGAGGAGG MUL_4367|M.ulcerans_Agy99 ---------------------------VGAGVAGGDGGTGGAGGAAGVGG Mflv_5091|M.gilvum_PYR-GCK --------------------------------------AAGAAGAAGAVG Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------AAGAAGKAGAVG MSMEG_0868|M.smegmatis_MC2_155 ---------------------------GQSTAAGPGKGGGGGGGGGGAIL TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------GDYTNVSGHGSAD MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------------------------LFASSTAALAYAQDPGT Mb3538|M.bovis_AF2122/97 AAGTGGTGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDATA--TGATGGTG Rv3508|M.tuberculosis_H37Rv AAGTGGTGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDATA--TGATGGTG MMAR_1594|M.marinum_M NSGFGGTGGTTGTHGDAGIGGDGGDGGTGGTGGQGTDAAAG-TGLTGGTG MUL_4367|M.ulcerans_Agy99 AAGTGGTG------GAAGVAGTGGDGGDGGAGGAGSDASL-----AGQAG Mflv_5091|M.gilvum_PYR-GCK SAGAAGEAGETGTWGNAGLPGKAG--DAGGAGAVGAAGAA------GTVG Mvan_1264|M.vanbaalenii_PYR-1 SAGTAGSAGAPGVWGNAGLPGAAG--AAGGAGAIGTAGVA------GAAG MSMEG_0868|M.smegmatis_MC2_155 IGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVI-AEGTGSTA TH_3810|M.thermoresistible__bu ---------------------------------------------YRTTD MAB_4284c|M.abscessus_ATCC_199 IDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPED Mb3538|M.bovis_AF2122/97 FSGGAGGAGGAGGNTGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIG Rv3508|M.tuberculosis_H37Rv FSGGAGGAGGAGGNTGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIG MMAR_1594|M.marinum_M YAGGTGGAGGAGGNSGLGGTNGSGGHGGTGGTGGTGGTGGSGADALDGSG MUL_4367|M.ulcerans_Agy99 FAGGSGGAGGVGGSAGAGGVNGSGGDGGAGAAGGAGGASAT--------- Mflv_5091|M.gilvum_PYR-GCK TAGATGGTG-TGANGGAGGVGGVGGTGAAGAAGGAG-------------- Mvan_1264|M.vanbaalenii_PYR-1 TAGATGGTG-VGGNGGAGQAGGIGGTGAAGAAGQAG-------------- MSMEG_0868|M.smegmatis_MC2_155 EGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATG--------- TH_3810|M.thermoresistible__bu NNALDGGHGGNGGNVGFFSLFNLGGAGGWG-------------------- MAB_4284c|M.abscessus_ATCC_199 TSTSAGGSAAVGGNAGLAGNAGLAGNAGLAGNAGLAGN------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 SEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTG------------ Mb3538|M.bovis_AF2122/97 GAGGTGG------------------------------------------- Rv3508|M.tuberculosis_H37Rv GTGGTGGKGGAGGAGGQGGS-------SGAGGTNGSGGAGGTGGQGGAGG MMAR_1594|M.marinum_M ASGHDGGDSGAGGDGGTGGAGGNAGTGAGAAGNNGDGGAGGTGGNSGAQA MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 --------------AGGTGGTGGAAGAGGAGG------------------ Rv3508|M.tuberculosis_H37Rv AGGAGADNPTGIGGAGGTGGTGGAAGAGGAGG------------------ MMAR_1594|M.marinum_M GDGGAGAANTTIGGTGGAGGSGGNIGAGGAGGQGGAAGTTSGVGGASGTS MUL_4367|M.ulcerans_Agy99 --------------VAGSGGVGGDGGAGGAAG------------------ Mflv_5091|M.gilvum_PYR-GCK ----------------GLGETGTTGGAGGVGG------------------ Mvan_1264|M.vanbaalenii_PYR-1 ----------------TAGETGVTGGVGGIGG------------------ MSMEG_0868|M.smegmatis_MC2_155 ----------------GRGGDGIDGGTGGAGGMG---------------- TH_3810|M.thermoresistible__bu ----------------GSGVDGVDVVGGNPDG------------------ MAB_4284c|M.abscessus_ATCC_199 ---------------AGLAGNAGLAGNAGLAG------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------TVALQPTPNQHLIVPTEQ------------------ Mb3538|M.bovis_AF2122/97 -----AVGTGGTGGVVGDVGN----------------------------- Rv3508|M.tuberculosis_H37Rv -----AIGTGGTGGAVGSVGN----------------------------- MMAR_1594|M.marinum_M GTSGQSIGTGGDGGAGGDGGTGTTGADAAAGSGLGGDIGGTGGAGGAGGT MUL_4367|M.ulcerans_Agy99 ---------GGVGAAS---------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -----EIYSGADGEATG--------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------AGIGGTGGKGGAGGTG-----------------FAGGAGGAGG Rv3508|M.tuberculosis_H37Rv -------AGIGGTGGTGGVGGAGGAGAAAAAGSSATGGAGFAGGAGGEGG MMAR_1594|M.marinum_M GGSGGTDSGVGGSGGVGGVGGTGGQGGAGSDNSANAGVAGGAGGQGGAGG MUL_4367|M.ulcerans_Agy99 ---------LGGDGG--------------------------HAGAGGAGG Mflv_5091|M.gilvum_PYR-GCK -----------------------------------------QGTAGGTGG Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------------QGTEGGTGG MSMEG_0868|M.smegmatis_MC2_155 -------ISAGGDGGS-------------------------ATGADSLGG TH_3810|M.thermoresistible__bu -------------------------------------------GTPGAHG MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------NAGLAGNAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------------APAPPPVQA Mb3538|M.bovis_AF2122/97 QGGSSGAG-------------------------------------GTNGS Rv3508|M.tuberculosis_H37Rv AGGNSGVG-------------------------------------GTNGS MMAR_1594|M.marinum_M TGGAAGSGGTGSVAGADGSSGDGGTGGLGGDGGAGGTGSMGAVDGGTGGQ MUL_4367|M.ulcerans_Agy99 EGLSGGFN--------------------------------------TGAA Mflv_5091|M.gilvum_PYR-GCK VGGIGGAG-------------------------------------STGAV Mvan_1264|M.vanbaalenii_PYR-1 VGGVGGVG-------------------------------------ATGGA MSMEG_0868|M.smegmatis_MC2_155 RGGTSWVQAG--------------------------------YGPTTGGK TH_3810|M.thermoresistible__bu ESHTPGVY--------------------------------------TDRQ MAB_4284c|M.abscessus_ATCC_199 LAGNAG---------------------------------------LAGNA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 SAPQPKIS-------------------------------------VPEPV Mb3538|M.bovis_AF2122/97 GGAGGTGGQGGAGGAGGAGADNPTGIGGAGGTGGTG-------------- Rv3508|M.tuberculosis_H37Rv GGAGGAGGKGGTGGAGGSGADNPTGAGFAGGAGGTG-------------- MMAR_1594|M.marinum_M GASGGAGGQGGTGGAAGAGTGGIQGAGGQGGTGGTGGTGGTGGDGAESTD MUL_4367|M.ulcerans_Agy99 GGIGGAGGAGGTG----------------GDSGGVG-------------- Mflv_5091|M.gilvum_PYR-GCK GGVGGKGIQGGQG------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GGVGGKGIQGGQG------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATG------------ TH_3810|M.thermoresistible__bu G------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAG------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AAPKPLSPPVAAP------------------------------------- Mb3538|M.bovis_AF2122/97 --------GAAGAGGAGGA-IGTGGTGGAVGSVGNAGIG----------- Rv3508|M.tuberculosis_H37Rv --------GAAGAGGAGGA-TGTGGTGGVVGATGSAGIGGAGGRGGDGGD MMAR_1594|M.marinum_M PSLAGQAGGQGGTGGTGGA-AGQGGTGSVTGAEGSAGDGGTGGLGGDGGT MUL_4367|M.ulcerans_Agy99 --------GVNGDGGAGGG-GGRGGDGGSSTSTS---------------- Mflv_5091|M.gilvum_PYR-GCK --------LQGGKGGDGGA-GGKGGDADSMGSAG---------------- Mvan_1264|M.vanbaalenii_PYR-1 --------LQGGQGGDGGT-GGTGGDATSMGEAG---------------- MSMEG_0868|M.smegmatis_MC2_155 ------NTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSG--- TH_3810|M.thermoresistible__bu ---------EDGEDGTGTG------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------LAGNAGLAGN-AGLAGNAGLAGNAG---------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------LPAAPPPAAPPLPEAPPIPAAPPVVP---------------- Mb3538|M.bovis_AF2122/97 ----------------------------------------------GTGG Rv3508|M.tuberculosis_H37Rv GASGLGLGLSGFDGGQGGQGGAGGSAGAGGIN--------------GAGG MMAR_1594|M.marinum_M GADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGG MUL_4367|M.ulcerans_Agy99 ----------------------------------------------GVGG Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------------ATGG Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------------ATGG MSMEG_0868|M.smegmatis_MC2_155 ---------------------------------------------HGGAA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------LAGNAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------------------------------------VPVVV Mb3538|M.bovis_AF2122/97 TGGVGGAGGA-----------------------------------GAAAA Rv3508|M.tuberculosis_H37Rv AGGNGGDGGD-----------------------------------GATGA MMAR_1594|M.marinum_M TGGQGGTGGDGAESTDPTLAAQAGGQGGTGGTGGAAGQGGTGSTMGAEGS MUL_4367|M.ulcerans_Agy99 AGGAGGNGGN------------------------------------AGFG Mflv_5091|M.gilvum_PYR-GCK KGGNGGNGGR-------------------------------------GGL Mvan_1264|M.vanbaalenii_PYR-1 KGGNGGNGGR-------------------------------------GSL MSMEG_0868|M.smegmatis_MC2_155 QGGNGGNGGN-----------------------------------GWVQA TH_3810|M.thermoresistible__bu IGGRGGNGGS---------------------------------------- MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGN-------------------------------------AGL MLBr_01183|M.leprae_Br4923 -----------------------------------------------MPL MAV_4827|M.avium_104 PPVPVPVPVR-------------------------------------IPV Mb3538|M.bovis_AF2122/97 AGSSATGGAGFAG----------------------GAG------------ Rv3508|M.tuberculosis_H37Rv AGLGDNGGVGGDG----------------------GAGGAAGNGGNAGVG MMAR_1594|M.marinum_M SGDGGTGGLGGDGGAGADNTTTVSTGAQGATGGTGGAGGQGGTGGAAGTG MUL_4367|M.ulcerans_Agy99 VSAGGTGGSAGDG----------------------GAG------------ Mflv_5091|M.gilvum_PYR-GCK FGKGGNAGNGADG------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 FGRGGNAGNGGNG------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 YDPNGPAGTTIDK------------------------------------- TH_3810|M.thermoresistible__bu --SSGTHPMAEDG------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAAVAG------------------------------------ MLBr_01183|M.leprae_Br4923 FLNAEPQALTAAA------------------------------------- MAV_4827|M.avium_104 PDPVSPPQLLAPPR------------------------------------ Mb3538|M.bovis_AF2122/97 -----GEGGAGGNSGVGGTNGSGGAG------------------------ Rv3508|M.tuberculosis_H37Rv LTAKAGDGGAAGNGGNGGAGGAGGAGDN---------------------- MMAR_1594|M.marinum_M TGGIQGAGGQGGTGGTGGTGGSGGDGTDNSTTPGAAGGAGGQGGTGGTGG MUL_4367|M.ulcerans_Agy99 -------GGAGGVDGVGGASGNGGAA------------------------ Mflv_5091|M.gilvum_PYR-GCK --------GTGGAGGAGGTGGTGGAG------------------------ Mvan_1264|M.vanbaalenii_PYR-1 --------GTGGNGGNGGTGGTGGNG------------------------ MSMEG_0868|M.smegmatis_MC2_155 ------GKAAGGNGGDGGFNGTGGAT------------------------ TH_3810|M.thermoresistible__bu -------------EHVKALDGRPGLD------------------------ MAB_4284c|M.abscessus_ATCC_199 ---------NAAVAGNAAVAGNAAVG------------------------ MLBr_01183|M.leprae_Br4923 ----------------NTLEGLSAAT------------------------ MAV_4827|M.avium_104 ------LSVPQPVQPPVRVPQPPSPP------------------------ . Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv --------------------------------------------NFNGGQ MMAR_1594|M.marinum_M AAGSGGTGSTMGAEGSSGDGGTGGLGGDGGEGGQGTTAWNPGDTGGQGAS MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -GAGGKGGTGGAGGSGADNPTGAGFAGGAGGTGGAAGAGGAG-------- Rv3508|M.tuberculosis_H37Rv GGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGGAGGAGTL------ MMAR_1594|M.marinum_M GGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGDGTDNSTTPG MUL_4367|M.ulcerans_Agy99 -GAGGAGGSGIGAG-------IDGGAGGAGGTGGAAGFPGGG-------- Mflv_5091|M.gilvum_PYR-GCK -GTGGTGGTG-----------GIGGAGSTGGTGGTGGTGGTG-------- Mvan_1264|M.vanbaalenii_PYR-1 -GTGGTGGTG-----------GIGGAGSTGGTGGTGGTGGTG-------- MSMEG_0868|M.smegmatis_MC2_155 ---GGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVN------ TH_3810|M.thermoresistible__bu -----------------------------GGNGSHGGNGGHG-------- MAB_4284c|M.abscessus_ATCC_199 ---------------------GVLNTGVSGAIGGSSHVGGAIN------- MLBr_01183|M.leprae_Br4923 ----------------------------VASNAAAAQLTTEI-------- MAV_4827|M.avium_104 ----------------------QVGGTVPQSPPQHQTPPGEGTP------ . Mb3538|M.bovis_AF2122/97 ---------------GATGTGGTGGVVGATGSA-GIGGAGGRGGDGGDG- Rv3508|M.tuberculosis_H37Rv ---GVGGSGGTGGDGGDAGSGGGGGFGGAAGKA-GGGGNGGRGGDGGDG- MMAR_1594|M.marinum_M AAGGAGGQGGTGGTGGAAGTGGTGSTMGAEGSS-GDGGSGGLGGDGGAGG MUL_4367|M.ulcerans_Agy99 ---------------GTTGAWGTGGAGGAGGAG-GAGDHGGVGVNPGDS- Mflv_5091|M.gilvum_PYR-GCK ------------------GTGGTGGTGGTGGTG-GTGGKGGTGGTGGAG- Mvan_1264|M.vanbaalenii_PYR-1 ------------------GTGGTGGTGGTGGTG-GTGGKGGTGGTGGDG- MSMEG_0868|M.smegmatis_MC2_155 -----------------AGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG- TH_3810|M.thermoresistible__bu ---------------------GRGGFLGIGGSG-GWGGHGGNGGDTDAD- MAB_4284c|M.abscessus_ATCC_199 -----------------ESLGGSGSVGGSTAVG--GGAHTGVGGGVSTG- MLBr_01183|M.leprae_Br4923 ---------------------APPAADDVSILL--AHFFSGHGRQYQAH- MAV_4827|M.avium_104 -----------------PKPDGPGNYGGGHVPTPGAGGSGGSGGGHVPT- . . * * Mb3538|M.bovis_AF2122/97 -----ASGLGLGLSGFDGGQGGQGGDGGSAGAG--GINGAGGAGGDGGDG Rv3508|M.tuberculosis_H37Rv -----ASGLGLGLSGFDGGQGGQGGAGGSAGAG--GINGAGGAGGNGGDG MMAR_1594|M.marinum_M QGTTGTAGAGTGGQGASGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTG MUL_4367|M.ulcerans_Agy99 -----------GTAGWAGGAGGAGGAGGSAAFN--GVNGAGGAGGNGGAG Mflv_5091|M.gilvum_PYR-GCK ------------------GTGGDGGTGGTGGTG-----GTGGTGGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 ------------------GTGGTGGTGGTGGTG-----GTGGTGGTGGTG MSMEG_0868|M.smegmatis_MC2_155 ------------------GDGALGGNGGTGGVG----LGNGGKGGNGGNG TH_3810|M.thermoresistible__bu -------------------------------------------GGNGGDG MAB_4284c|M.abscessus_ATCC_199 -----------------VGVGSHVGGGISESLG--------GSGSVGGST MLBr_01183|M.leprae_Br4923 -------------------------------------------ASQGATN MAV_4827|M.avium_104 -------------------------------------------PGAGGSG . *. Mb3538|M.bovis_AF2122/97 GDG-----------------------------------------ATGAAG Rv3508|M.tuberculosis_H37Rv GDG-----------------------------------------ATGAAG MMAR_1594|M.marinum_M GTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTGSTIGSAGTAG MUL_4367|M.ulcerans_Agy99 GGG-----------------------------------------GAGASG Mflv_5091|M.gilvum_PYR-GCK GAG----------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GAG----------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNG-------------------------------------------GTYV TH_3810|M.thermoresistible__bu GNG----------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AVG----------------------------------------------- MLBr_01183|M.leprae_Br4923 HQD----------------------------------------------- MAV_4827|M.avium_104 GSG----------------------------------------------- . Mb3538|M.bovis_AF2122/97 LGDNGGVGGDG----------------------GAGGAAGNGGNAGVGLT Rv3508|M.tuberculosis_H37Rv LGDNGGVGGDG----------------------GAGGAAGNGGNAGVGLT MMAR_1594|M.marinum_M DGGTGGLGGDGGTGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTG MUL_4367|M.ulcerans_Agy99 IG-AGVAGGDG-------------------------GTGGTGGAAGT--- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 DPSHTGAGGNG----------------------GNGGAGRIRVNNGTATG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 AKAGDGGAAGNGGNGGAGGAGGAGDNNFN-------GGQGGAGGQGGQGG Rv3508|M.tuberculosis_H37Rv AKAGDGGAAGNGGNGGAGGAGGAGDNNFN-------GGQGGAGGQGGQGG MMAR_1594|M.marinum_M GIQGAGGQGGTGGTGGQGGTGGDGADSTDPTLAGQAGGQGGTGGTGGAAG MUL_4367|M.ulcerans_Agy99 -----GGAAGTGGTGGAAGAAGS-------------AGDGGAGGAGGAGD Mflv_5091|M.gilvum_PYR-GCK -----DGTGGTGGTGGTGGQGGQ-------------GGQGGTGGTGGQGG Mvan_1264|M.vanbaalenii_PYR-1 -----DGLGGTGGTGGTGGFGGQ-------------GGQGGTGGTGGQGG MSMEG_0868|M.smegmatis_MC2_155 -----TATGGNGGNGGNGDADGHR------------GGKGGDGGEALIRA TH_3810|M.thermoresistible__bu ------GSAGRGGTGGLRGVFGIN------------GGNGRAG------- MAB_4284c|M.abscessus_ATCC_199 ------GGAHTGVGGGVSTGVGVG-------------SHVGGGISESLGG MLBr_01183|M.leprae_Br4923 --------LIQSLLTSSSAYAGT--------------ETANHDSL----- MAV_4827|M.avium_104 -----GGHVPTPGTGGPGGTGGSG------------GGHVPTPGAGTPGG . * Mb3538|M.bovis_AF2122/97 LGGASTTS-----------------------------------INANGGA Rv3508|M.tuberculosis_H37Rv LGGASTTS-----------------------------------INANGGA MMAR_1594|M.marinum_M QGGTGSTSGSEGSSGDGGTGGLGGDGGAGADNTTTVSAGAQGATGGTGGA MUL_4367|M.ulcerans_Agy99 DGSAGVVS------------------------------------------ Mflv_5091|M.gilvum_PYR-GCK LGGGGGTG------------------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 LGGVGGTG------------------------------------------ MSMEG_0868|M.smegmatis_MC2_155 TVIGSNASG-----------------------------------TATGGD TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SGSVGG-------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 SGGGHLPFP----------------------------------------- Mb3538|M.bovis_AF2122/97 GGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGAGGG------------ Rv3508|M.tuberculosis_H37Rv GGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGG------------ MMAR_1594|M.marinum_M GGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAG MUL_4367|M.ulcerans_Agy99 -GDPGTAGKAG--------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGNGGTLGATN--------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 --------GGFGGAAG------------KAGGGGNGGVGGDGGEG----- Rv3508|M.tuberculosis_H37Rv --------GGFGGAAG------------KAGGGGNGGVGGDGGEG----- MMAR_1594|M.marinum_M GAGGQGGTGGTGGAAGQGGTGSTMGSDGSSGDGGTGGLGGDGGEGGQGTT MUL_4367|M.ulcerans_Agy99 ------------------------------GAGGAGGVGGN--------- Mflv_5091|M.gilvum_PYR-GCK ------------------------------GQGGTGG------------- Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------GTGGTGG------------- MSMEG_0868|M.smegmatis_MC2_155 ------------------------------GTGGAATIVAYNVVQAN--- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ------------------------ATGLGLD------------------- Rv3508|M.tuberculosis_H37Rv ------------------------ASGLGLG------------------- MMAR_1594|M.marinum_M GTAGAGTGGQGASGGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ------------LSGFAGGQGGQGGAGGNAG------------------- Rv3508|M.tuberculosis_H37Rv ------------LSGFDGGQGGQGGAGGSAG------------------- MMAR_1594|M.marinum_M TGGDGADSTDPTLAGQAGGQGGTGGTGGAAGQGGTGSVAGTDGSSGDGGT MUL_4367|M.ulcerans_Agy99 --------------GVAGGVNGSGGAG----------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------TGGQGGTGGTG----------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------------TGGQGGTGGTG----------------------- MSMEG_0868|M.smegmatis_MC2_155 ---------PQASGTATDGHGGSGING----------------------- TH_3810|M.thermoresistible__bu -------------------LGGRGXXX----------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------STAVGGGAHTG----------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 --------------------------------------------AGGING Rv3508|M.tuberculosis_H37Rv --------------------------------------------AGGING MMAR_1594|M.marinum_M GGLGGHGGAGADNTTTVSAGAQGATGGTGGAGGTGGTGGAAGTGTGGIQG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------G Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------G Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------G MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------G TH_3810|M.thermoresistible__bu -------------------------------------------------X MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------------VG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------G Mb3538|M.bovis_AF2122/97 AGGTGGTG------GAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFG- Rv3508|M.tuberculosis_H37Rv AGGAGGTG------GAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFG- MMAR_1594|M.marinum_M AGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGQGG MUL_4367|M.ulcerans_Agy99 AGGAGGTG------GAGASGVPASVD----GGDGGAGGAGGAAGTGGSG- Mflv_5091|M.gilvum_PYR-GCK TGGTGGTG------GAGGD-----------GGLGGLGGFGGSGGTGGQG- Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTG------GAGGD-----------GGLGGLGGFGGVGGTGGQG- MSMEG_0868|M.smegmatis_MC2_155 HGGNGGQG------TIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDG- TH_3810|M.thermoresistible__bu GGGVG------------------------AAVRSGNGVFSGGGGTPSAG- MAB_4284c|M.abscessus_ATCC_199 GGVNTGVG---------------------VGSHVGGGISESLGGSGSVG- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AGSTP-------------------------GGSGGGHLPTPGAGTPGGG- Mb3538|M.bovis_AF2122/97 -------AGVPGDGGIGG-------------------------------- Rv3508|M.tuberculosis_H37Rv -------AGVPGDGGDGGNAGFGA-------------------------- MMAR_1594|M.marinum_M TGSTSGSAGSSGDGGTGGLGGDGGEGGQGTTGTAGAGTGGQGASGGAGGQ MUL_4367|M.ulcerans_Agy99 --------GSAGNTGAGG-------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ----------------TGGAGGAGGAGGAGDAGADGDPSID-------GG Rv3508|M.tuberculosis_H37Rv ------------GVPGDGGIGGTGGAGGAGGAGADGDPSID-------GG MMAR_1594|M.marinum_M GGTGGAAGTGTGGTQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGG MUL_4367|M.ulcerans_Agy99 ----------------AGGAGGAGGSAASTGVNGDG-------------G Mflv_5091|M.gilvum_PYR-GCK ------------------GLGGPGGSTG---------------------G Mvan_1264|M.vanbaalenii_PYR-1 ------------------GQGGPGGSTG---------------------G MSMEG_0868|M.smegmatis_MC2_155 ------------VVNTTANAANPGSATGTATGG----------------D TH_3810|M.thermoresistible__bu -------------------FGVPTTIQFP--------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------GSTAVGGGAHTSAIN---------------DA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------LGGFGGGHAPAPGG----------------G Mb3538|M.bovis_AF2122/97 QGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGD------- Rv3508|M.tuberculosis_H37Rv QGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGD------- MMAR_1594|M.marinum_M QGGTGGTGGAAGQGGTGSTMGSAGTAGDGGTGGLGGHGGTGADNTTTVSA MUL_4367|M.ulcerans_Agy99 AGGAGGVGGLGGDS--AATAGGGGAGGDGGKGGAGGAGVNGVG------- Mflv_5091|M.gilvum_PYR-GCK AGGAGGQAGTAGKG-----------GLFGGSGSAGKAGATGAA------- Mvan_1264|M.vanbaalenii_PYR-1 AGGAGGQAGVAGKG-----------GLFGGSGSAGTAGVTGAS------- MSMEG_0868|M.smegmatis_MC2_155 GGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEAS------ TH_3810|M.thermoresistible__bu -AGSCTSRAVSREG-----------IMPSSRAASARAGAACAS------- MAB_4284c|M.abscessus_ATCC_199 LGGSGSVGGSTAVG------------GGAHTSAINESMNSSIN------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 LGGGGGHAPAPGGG------------LGGFGGGHSGGGLGGLG------- Mb3538|M.bovis_AF2122/97 -------GDGFIGGSGGTG-----GTGGDAGAGGLANTGGTAGNAGIG-- Rv3508|M.tuberculosis_H37Rv -------GDGFIGGSGGTG-----GTGGDAGVGGLANTGGTAGNAGIG-- MMAR_1594|M.marinum_M GAQGATGGTGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGQGGTGGT MUL_4367|M.ulcerans_Agy99 ---------GGDGGKGGTG-----GAGGAGGAGSDGIIPSNGGLG----- Mflv_5091|M.gilvum_PYR-GCK ---------GASGGKGAQG-----ATGAQGATGAQGATG----------- Mvan_1264|M.vanbaalenii_PYR-1 ---------GASGGKGAQG-----ATGAQGATGAQGATG----------- MSMEG_0868|M.smegmatis_MC2_155 --------NGGVAGNGGNA--LVMAAGTTGVATGNTATGGDGGAAT---- TH_3810|M.thermoresistible__bu ------------------------STSRSRRSFCCSRA------------ MAB_4284c|M.abscessus_ATCC_199 ------------------------ASHSSSMNESFGSSMG---------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------GGHK-------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GTDSTDPTLVGQAGGQGGTGGTGGAAGQGGTGSVTGAEGSAGDGGSGGLG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------GAGGRGGDGGAGDS------GALSQ Rv3508|M.tuberculosis_H37Rv -------------------------GAGGRGGDGGAGDS------GALSQ MMAR_1594|M.marinum_M GHGGTGADNTTAVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQ MUL_4367|M.ulcerans_Agy99 -------------------------GNGGNGGNGGQAFG----------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 DGNGFAGGQGGQG------------------------------------- Rv3508|M.tuberculosis_H37Rv DGNGFAGGQGGQG------------------------------------- MMAR_1594|M.marinum_M GGTGGTGGQGGTGGTGTDSTDPTLAGQAGGQGGTGGTGGAAGSGGTGSTM MUL_4367|M.ulcerans_Agy99 DGVGGAGGIGGKG------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -ATGAAGKAGATG------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -ATGASGAQGSAG------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -TAGATGGAGGFSN------------------------------------ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -SHGAAGTGFEAQG------------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GAEGSSGDGGTGGLGGDGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ----GAGGNAGAGGINGAGGTGGTGGAGGDGAPATLIGGPDGGDGGQGG- Rv3508|M.tuberculosis_H37Rv ----GVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGD MMAR_1594|M.marinum_M AAGTGTGGTQGAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGT MUL_4367|M.ulcerans_Agy99 -------GNAAIGTIVINGGVGGAGGSGG--------------------- Mflv_5091|M.gilvum_PYR-GCK --------AAGAAGAAGSAGTTGAQGSAG--------------------- Mvan_1264|M.vanbaalenii_PYR-1 --------SAGSAGVAGSAGTTGAQGSAG--------------------- MSMEG_0868|M.smegmatis_MC2_155 -------IAAIHGAITDSTAISGHGGAGN--------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------HAQGHASETAHTTLPGAEHH----------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGQG---------------------------------------------- MMAR_1594|M.marinum_M GGTGGAAGSGGTGSTMGAEGSSGDGGTGGLGGDGGTGGQGTTAVNPGDTG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ----------------GAGFGSG----VAG-------------------- Rv3508|M.tuberculosis_H37Rv ---------GIGGAGGNAGFGAG----VPGDGGIGGTGGAGGAGGAGAD- MMAR_1594|M.marinum_M GQGASGGAGGTGGTGGAAGTGTGGTQGAGGQGGTGGTGGQGGTGGDGTDN MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ---------------------------------------------AAGAG Rv3508|M.tuberculosis_H37Rv ----GDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAG MMAR_1594|M.marinum_M STTPGAAGGAGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDGGTGGLGGAG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GNGGKG----------------GDGGTGGTG------------------- Rv3508|M.tuberculosis_H37Rv GNGGDGDGFI-----------GGSGGTGGTGGDAGVGGLANTGGTAGNAG MMAR_1594|M.marinum_M GTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAAGTG-TGGIQGAGGQGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ----------------------GTNFAGGQGG------------------ Rv3508|M.tuberculosis_H37Rv IGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGI----- MMAR_1594|M.marinum_M TGGAGGSGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGSGGTGSTMG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------AGGRGGA Rv3508|M.tuberculosis_H37Rv --------------------------------------NGAGGTGGTGGA MMAR_1594|M.marinum_M AEGSSGDGGTGGLGGAGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGA MUL_4367|M.ulcerans_Agy99 ----------------------------------------------LGGA Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------------TNGA Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------------TNGA MSMEG_0868|M.smegmatis_MC2_155 -----------------------------------------------GGN TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GGNGANG------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGG MMAR_1594|M.marinum_M AGTGTGGIQGAGGQGGTGGTGGQGGTGGDGAESTDPTLAGQAGGQGGTGG MUL_4367|M.ulcerans_Agy99 TEDGVGG------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK N--GANG------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 N--GANG------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGKGADGWVQAYDPAGPVG------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv TGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAAS-GD MMAR_1594|M.marinum_M TGGAAGQGGTGSVAGTDGSAGDGGTGGLGGHGGAGADNTTTVSAGAQGAT MUL_4367|M.ulcerans_Agy99 -------------------------------------------------V Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -----------------------------------------------SKI TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 VGDNAAGGDGGNG-----------GAGGLGGGGGTGGTN----------- Rv3508|M.tuberculosis_H37Rv GGNGGAGGAGGNG-----------GAGGLGGGGGTGGTN----------- MMAR_1594|M.marinum_M GGTGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGTGGIGGTGTDSTD MUL_4367|M.ulcerans_Agy99 GCAGGAGGNGGRG-------------DMLFTVGGSGGTG----------- Mflv_5091|M.gilvum_PYR-GCK -SQGAAGKAGATG-----------------TTGATGAAG----------- Mvan_1264|M.vanbaalenii_PYR-1 -SQGAAGKAGATG-----------------TTGATGAAG----------- MSMEG_0868|M.smegmatis_MC2_155 ANSSAVAGNGGDG-----------------GVNGTGGAS----------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 --------------------------------------GNGGLGGGGGN- Rv3508|M.tuberculosis_H37Rv --------------------------------------GNGGLGGGGGN- MMAR_1594|M.marinum_M PSQIAQAGGQGGTGGTGGAAGQGGTGSTMGSAGTAGDGGTGGLGGGGGTG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ------------------------GGAGGAGGTPTG-------------- Rv3508|M.tuberculosis_H37Rv ------------------------GGAGGAGGTPTG-------------- MMAR_1594|M.marinum_M ADNTTAVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGT MUL_4367|M.ulcerans_Agy99 -------------------------GDGGGGGSASG-------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------EDGDAGSGGSG-------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------DAGDPGSEAVD-------------- MSMEG_0868|M.smegmatis_MC2_155 ------------------------GGDGGNGGNTSVWK------------ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------SGTEGTG Rv3508|M.tuberculosis_H37Rv -------------------------------------------SGTEGTG MMAR_1594|M.marinum_M GGTGGIGGTGTDSTDPTLAGQAGGQGGTGGTGGAAGTGGTGSVTGTDGTA MUL_4367|M.ulcerans_Agy99 -------------------------------------------SGTGGSG Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------INGGAG Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------INGGAG MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------SGGQTAD TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GDGGDAGAGGNGGS------------------------------ATGVGN Rv3508|M.tuberculosis_H37Rv GDGGDAGAGGNGGS------------------------------ATGVGN MMAR_1594|M.marinum_M GDGGTGGLGGHGGAGADNTTTVSAGAQGATGGTGGAGGTGGTGGAAGTGT MUL_4367|M.ulcerans_Agy99 GTGGVGGIGGDGKL------------------------------------ Mflv_5091|M.gilvum_PYR-GCK GAGGAGGEGGEGGD------------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 GAGGAGGEGGEGGA------------------------------------ MSMEG_0868|M.smegmatis_MC2_155 GEHNTGGNGGNGGD------------------------------------ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GGNGGDGGN--GGDGGNGAPGGFGGG----------AGAGGLGGSGAGGG Rv3508|M.tuberculosis_H37Rv GGNGGDGGN--GGDGGNGAPGGFGGG----------AGAGGLGGSGAGGG MMAR_1594|M.marinum_M GGTQGAGGQ--GGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGG MUL_4367|M.ulcerans_Agy99 GGFGGDGGD--GGDGGFGVIGGQGGG----------GGFGGLGGTGAGG- Mflv_5091|M.gilvum_PYR-GCK GGKGGAGAE--GGAGGGGGAGGSGAG-----------GAGGAGGSGGSGG Mvan_1264|M.vanbaalenii_PYR-1 GGAGGDGSE--GGAGGSGGAGGSGTG-----------GAGGAGGSGGSGG MSMEG_0868|M.smegmatis_MC2_155 GSEPGPGGNGAGGAGGNGGTGGTTAGG---------SGNGGNGGNGGNGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 TDGDDGNGGSPGTDGS---------------------------------- Rv3508|M.tuberculosis_H37Rv TDGDDGNGGSPGTDGS---------------------------------- MMAR_1594|M.marinum_M AAGSGGTGSVTGTDGTAGDGGTGGLGGDGGAGADNTTTVSAGAQGATGGT MUL_4367|M.ulcerans_Agy99 APSDKGINGEPGNPG----------------------------------- Mflv_5091|M.gilvum_PYR-GCK SGGSGGSGGAAGDSDD---------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 SGGAGGSGGAAGDSD----------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ADGTPGTAGTTGANNP---------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGAGGSGGTGGDGTDNSTTPG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M AAGGAGGQGGTGGTGGAAGQGGTGSTMGSDGSSGDGGTGGLGGDGGGAGQ MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GTTGTAGAGTGGQGASGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M TGGTGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTGSTMGAEGSSGD MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GGTGGLGGHGGAGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M TQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQ MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GGTGSTMGSAGTAGDGGTGGLGGGGGTGADNTTTVSAGAQGATGGTGGAG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GQGGTGGAAGTGTGGIQGAGGQGGTGGTGGTGGIGGTGTDSTDPTLAGQA MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------- Rv3508|M.tuberculosis_H37Rv -------------------- MMAR_1594|M.marinum_M GGQGGTGETGGAAGSGGTGS MUL_4367|M.ulcerans_Agy99 -------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------- TH_3810|M.thermoresistible__bu -------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------- MLBr_01183|M.leprae_Br4923 -------------------- MAV_4827|M.avium_104 --------------------