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M. bovis AF2122 / 97 Mb3538 (PE_PGRS54)

annotation: PE-PGRS family protein
coordinates: 3876565 - 3880947
length: 1460

MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADEVSARIAALFGGFGLEYQAISAQVA
AYHQRFVQALSTGAGAYASAEAAAAEQIVLGVINAPTQALLGRPLIGDGANATTPGGAGGAGGLLFGNGG
AGAAGAPGQAGGPGGPAGLWGNGGPGGAGGSGGGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGL
IWGGGGAGGVGGAGGGTGGAGGRAELLFGAGGAGGAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAG
GAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGGTGGAGGDGVLGGV
GGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVGVGGTGGQGGAGGMGGSGADNASGIGADGGAGGTG
GNAGAGGAGGAAGTGGTGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDATATGATGGTGFSGGAGGAGGAG
GNTGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIGGAGGTGGAGGTGGTGGAAGAGGAGGAVGTGGT
GGVVGDVGNAGIGGTGGKGGAGGTGFAGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADN
PTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVGGAGGAGAAAAAGSSATG
GAGFAGGAGGEGGAGGNSGVGGTNGSGGAGGAGGKGGTGGAGGSGADNPTGAGFAGGAGGTGGAAGAGGA
GGATGTGGTGGVVGATGSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGDGGSAGAGGINGAGGA
GGDGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDN
NFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGAGGG
GGFGGAAGKAGGGGNGGVGGDGGEGATGLGLDLSGFAGGQGGQGGAGGNAGAGGINGAGGTGGTGGAGGD
GAPATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGGAGDAGADGDPSIDGGQG
GAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGAGGLANTGGT
AGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGGAGGNAGAGGINGAGGTGGTGGAGGDGAPAT
LIGGPDGGDGGQGGGAGFGSGVAGAAGAGGNGGKGGDGGTGGTGGTNFAGGQGGAGGRGGAGGNGANGVG
DNAAGGDGGNGGAGGLGGGGGTGGTNGNGGLGGGGGNGGAGGAGGTPTGSGTEGTGGDGGDAGAGGNGGS
ATGVGNGGNGGDGGNGGDGGNGAPGGFGGGAGAGGLGGSGAGGGTDGDDGNGGSPGTDGS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3538PE_PGRS54-100% (1460)PE-PGRS family protein
M. bovis AF2122 / 97Mb3541PE_PGRS550.050.47% (1811) PE-PGRS family protein
M. bovis AF2122 / 97Mb3543PE_PGRS570.074.56% (1022) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5091-0.050.36% (824) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3508PE_PGRS540.071.71% (1697) PE-PGRS family protein
M. leprae Br4923MLBr_01183-9e-1441.76% (91) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-5e-5933.08% (520) hypothetical protein MAB_4284c
M. marinum MMMAR_1594-0.055.77% (1594) PE-PGRS family protein
M. avium 104MAV_4827-1e-2848.81% (168) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-17141.94% (1061) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-2e-5141.53% (301) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.053.54% (1117) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-0.047.56% (862) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb3538|M.bovis_AF2122/97            --------------------------------MSFVLIAPEFVTAAAGD-
Rv3508|M.tuberculosis_H37Rv         --------------------------------MSFVLIAPEFVTAAAGD-
MMAR_1594|M.marinum_M               --------------------------------MSYMSISPEIVSSAAGE-
MUL_4367|M.ulcerans_Agy99           --------------------------------MSFVSVGPGLLEAAARD-
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------MSIIDF
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------------------------------MNIVLGVSMAP
                                                                                      

Mb3538|M.bovis_AF2122/97            -LTNLGSSISAANASAASATTQVLA-----AGADEVSARIAALFGGFGLE
Rv3508|M.tuberculosis_H37Rv         -LTNLGSSISAANASAASATTQVLA-----AGADEVSARIAALFGGFGLE
MMAR_1594|M.marinum_M               -LANIGSTVSAANAAAAVATTELLA-----AGSDEVSTRIAALFGANGVE
MUL_4367|M.ulcerans_Agy99           -LAGLGAGLREANLAAAGATVGVLP-----AAGDEVSAAIAELFGGFGRE
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------MVTFGGGA--
Mvan_1264|M.vanbaalenii_PYR-1       ----MMFLAPPGGPGPISAAIQLTS-----TGSEATEPWYVVSFGGSG--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ILNLFRDPVEAASYVADPEAALANAG---------LSAVSAAQVGAVMPV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                SSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREG
                                                                                      

Mb3538|M.bovis_AF2122/97            YQAISAQVAAYHQRFVQALSTGAGAYASAEAA------AAEQIVLGVINA
Rv3508|M.tuberculosis_H37Rv         YQAISAQVAAYHQRFVQALSTGAGAYASAEAA------AAEQIVLGVINA
MMAR_1594|M.marinum_M               YQAISAQIASFHDRFVAALNTGTSSYVWAEAT------NVEQNLLNAVNA
MUL_4367|M.ulcerans_Agy99           YQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQELEQQALGVVNA
Mflv_5091|M.gilvum_PYR-GCK          ----TPTPTSLGAAAVDLSGTSCG--------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----APTPNNLAASLVDLSGTSCG--------------------------
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VAESVASNYGYQSQWVNTGNPIHDLSGNLQN-------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AADAGLQLSSIGVTWTDQLEAAALRDALAARR------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            PTQ-----------------------------------------------
Rv3508|M.tuberculosis_H37Rv         PTQ-----------------------------------------------
MMAR_1594|M.marinum_M               PVQ-----------------------------------------------
MUL_4367|M.ulcerans_Agy99           PSM-----------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----------------------------------ALLGRPLIGDGAN-AT
Rv3508|M.tuberculosis_H37Rv         ----------------------------------ALLGRPLIGDGAN-AT
MMAR_1594|M.marinum_M               ----------------------------------TLLGRPLIGNGAN-AT
MUL_4367|M.ulcerans_Agy99           ----------------------------------ALFGRPSIGNGVDGVA
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------LICNGQD---
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------LICNGQD---
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN-GT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------YYAAQPDGPSILS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------------------IDNVMLVSAFLAA
                                                                                      

Mb3538|M.bovis_AF2122/97            TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG
Rv3508|M.tuberculosis_H37Rv         TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG
MMAR_1594|M.marinum_M               TPGGAGGDGGLLYGSGGNGA-AGAPGQAGGAGGSAGLWGNGGSGGSGGIG
MUL_4367|M.ulcerans_Agy99           GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGGVG
Mflv_5091|M.gilvum_PYR-GCK          ---GTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGLFG--GNGGNGGNG
Mvan_1264|M.vanbaalenii_PYR-1       ---GTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGLFG--GNGGNGGNG
MSMEG_0868|M.smegmatis_MC2_155      ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAG
TH_3810|M.thermoresistible__bu      ------------------------VDGDGGSGGRTGLFSKLSRGGD----
MAB_4284c|M.abscessus_ATCC_199      PSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAES
                                                                                      

Mb3538|M.bovis_AF2122/97            GGTGGAGGAGGWLFGVGGAGGVGGAGGG----------------------
Rv3508|M.tuberculosis_H37Rv         GGTGGAGGAGGWLFGVGGAGGVGGAGGG----------------------
MMAR_1594|M.marinum_M               GGTGGNGGSGGWLLGRGGIGGAGGTGGGSGGSGGGAWLFGDGGAGGMGGT
MUL_4367|M.ulcerans_Agy99           -AAGMTGGS-----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          LGGGN---------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       LGSGD---------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      LD------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      FG------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                YG------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GGSGGGFGGTGGHGGLLYGNGGAGGAGATGQTGGSGGWAALWGRGGAGGA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GGDNGGFAGGDGGHGGLLCGAGGDGGLGGGDGGNAGWLLGFGGHGGAGGD
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -----------------------------TGGAGGPGGLIWGGGGAGGVG
Rv3508|M.tuberculosis_H37Rv         -----------------------------TGGAGGPGGLIWGGGGAGGVG
MMAR_1594|M.marinum_M               GGFAGGEGGNGGWLLGFGGHGGTGGIGGGTGGAGGAGGLVMGFGGHGGTG
MUL_4367|M.ulcerans_Agy99           ------------------------------GGAGGGGGWLWGAGGSGGAA
Mflv_5091|M.gilvum_PYR-GCK          ------------------------------GGNGGNAGAFALFGN-----
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------GGNGGDAGLFSLFGR-----
MSMEG_0868|M.smegmatis_MC2_155      ------------------------------GGNGGSGGLLMGIGGAGGAG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GAGGGTGGAGGRAELLFGAGGAGGAGGAGTDGGPG---------------
Rv3508|M.tuberculosis_H37Rv         GAGGGTGGAGGRAELLFGAGGAGGAG---TDGGPG---------------
MMAR_1594|M.marinum_M               GIGGGAGGAGGQAALLFGHGGGGGAGGVGTAGGAGGAGGDGGNPGWLLGR
MUL_4367|M.ulcerans_Agy99           GAGG----------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GVG-----------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -----------------ATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAG
Rv3508|M.tuberculosis_H37Rv         -----------------ATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAG
MMAR_1594|M.marinum_M               AGSGGDGGAGGAATTVGATGGVGGHGGAGGRGGVLMGGGAGGDGGAGGAG
MUL_4367|M.ulcerans_Agy99           ---------------------------SGGSGGWLWG----NAGQTAGAG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------------ADGTSAHVDGGTGGTG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GAGSDGGALGG---TGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQG
Rv3508|M.tuberculosis_H37Rv         GAGSDGGALGG---TGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQG
MMAR_1594|M.marinum_M               ADGSNGVGDGGNGATGGGGGVGGDGGAGGQAALLFGCGGTGGHAGAGGAG
MUL_4367|M.ulcerans_Agy99           --------------VGGAGGAGGAGDAGDQGVSGVAPGEAGAVGFAGGAG
Mflv_5091|M.gilvum_PYR-GCK          ---------------GGNGGNGGVGVVG-------------ATGAVGAPG
Mvan_1264|M.vanbaalenii_PYR-1       ---------------GGNGGNGGVGIAG-------------ATGAVGAPG
MSMEG_0868|M.smegmatis_MC2_155      ---------------GTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAA
TH_3810|M.thermoresistible__bu      ---------------GGDGGLGGNGGHG----------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------DLQFGNRDTTAIG---------DGAVAVGGSNSGP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------DAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAP
                                                                                      

Mb3538|M.bovis_AF2122/97            GTGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVG
Rv3508|M.tuberculosis_H37Rv         GTGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVG
MMAR_1594|M.marinum_M               GGGGTGADSLTG-IGGAGGDGGIGGASGQAGAG-GAGNLFSHNGSRGHAG
MUL_4367|M.ulcerans_Agy99           GAGGAGGNGVGGGVNGAGGAGGAG-------------------------G
Mflv_5091|M.gilvum_PYR-GCK          VAGATGATGVTSGVVGGNGEDAVG--------------------------
Mvan_1264|M.vanbaalenii_PYR-1       VAGATGATGVTSNVTGGNGADAVG--------------------------
MSMEG_0868|M.smegmatis_MC2_155      GNGGDGGNGGFGYVLIAGPNVTVG-----------------------SET
TH_3810|M.thermoresistible__bu      -----GGTGIISLLSLAG--------------------------------
MAB_4284c|M.abscessus_ATCC_199      IASGQGSTAVNGDVRDSNIINADHG-----------------------SN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                LKQVLQTTTFLDVSVAEEPETALAR-------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            VGGTGGQGGAG---------------------------------------
Rv3508|M.tuberculosis_H37Rv         VGGTGGQGGAGGAGAAGADAPASTGLTGGTGFAGGAGGVGGQGGNAIAGG
MMAR_1594|M.marinum_M               IGGDGGDGGTGGTGGEGTDAAAGSGLTGGTGYAGGTGGTGGAGGNSGLGG
MUL_4367|M.ulcerans_Agy99           VGGGGGAGASG---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          YGATGAAGAAG---------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       YGATGAAGAAG---------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      RGGTGGAGGTG---------------------------------------
TH_3810|M.thermoresistible__bu      ---NGGNGGNG---------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VGVDQSQTRVG---------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -GAALAAANAP---------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -----------------GMGGSGADNASGIGADGGAGGTGGNAGAGGAGG
Rv3508|M.tuberculosis_H37Rv         INGSGGAGGTGGQGGAGGMGGSGADNASGIGADGGAGGTGGNAGAGGAGG
MMAR_1594|M.marinum_M               TNGSGGHGGTGGTGGTGGTGGSGADNTTGIGGDGGQGGTGGDAGAGGAGG
MUL_4367|M.ulcerans_Agy99           ---------------------------VGAGVAGGDGGTGGAGGAAGVGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------AAGAAGAAGAVG
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------AAGAAGKAGAVG
MSMEG_0868|M.smegmatis_MC2_155      ---------------------------GQSTAAGPGKGGGGGGGGGGAIL
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------GDYTNVSGHGSAD
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------------------------LFASSTAALAYAQDPGT
                                                                                      

Mb3538|M.bovis_AF2122/97            AAGTGGTGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDATA--TGATGGTG
Rv3508|M.tuberculosis_H37Rv         AAGTGGTGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDATA--TGATGGTG
MMAR_1594|M.marinum_M               NSGFGGTGGTTGTHGDAGIGGDGGDGGTGGTGGQGTDAAAG-TGLTGGTG
MUL_4367|M.ulcerans_Agy99           AAGTGGTG------GAAGVAGTGGDGGDGGAGGAGSDASL-----AGQAG
Mflv_5091|M.gilvum_PYR-GCK          SAGAAGEAGETGTWGNAGLPGKAG--DAGGAGAVGAAGAA------GTVG
Mvan_1264|M.vanbaalenii_PYR-1       SAGTAGSAGAPGVWGNAGLPGAAG--AAGGAGAIGTAGVA------GAAG
MSMEG_0868|M.smegmatis_MC2_155      IGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVI-AEGTGSTA
TH_3810|M.thermoresistible__bu      ---------------------------------------------YRTTD
MAB_4284c|M.abscessus_ATCC_199      IDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPED
                                                                                      

Mb3538|M.bovis_AF2122/97            FSGGAGGAGGAGGNTGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIG
Rv3508|M.tuberculosis_H37Rv         FSGGAGGAGGAGGNTGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIG
MMAR_1594|M.marinum_M               YAGGTGGAGGAGGNSGLGGTNGSGGHGGTGGTGGTGGTGGSGADALDGSG
MUL_4367|M.ulcerans_Agy99           FAGGSGGAGGVGGSAGAGGVNGSGGDGGAGAAGGAGGASAT---------
Mflv_5091|M.gilvum_PYR-GCK          TAGATGGTG-TGANGGAGGVGGVGGTGAAGAAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1       TAGATGGTG-VGGNGGAGQAGGIGGTGAAGAAGQAG--------------
MSMEG_0868|M.smegmatis_MC2_155      EGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATG---------
TH_3810|M.thermoresistible__bu      NNALDGGHGGNGGNVGFFSLFNLGGAGGWG--------------------
MAB_4284c|M.abscessus_ATCC_199      TSTSAGGSAAVGGNAGLAGNAGLAGNAGLAGNAGLAGN------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                SEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTG------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GAGGTGG-------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GTGGTGGKGGAGGAGGQGGS-------SGAGGTNGSGGAGGTGGQGGAGG
MMAR_1594|M.marinum_M               ASGHDGGDSGAGGDGGTGGAGGNAGTGAGAAGNNGDGGAGGTGGNSGAQA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------AGGTGGTGGAAGAGGAGG------------------
Rv3508|M.tuberculosis_H37Rv         AGGAGADNPTGIGGAGGTGGTGGAAGAGGAGG------------------
MMAR_1594|M.marinum_M               GDGGAGAANTTIGGTGGAGGSGGNIGAGGAGGQGGAAGTTSGVGGASGTS
MUL_4367|M.ulcerans_Agy99           --------------VAGSGGVGGDGGAGGAAG------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------GLGETGTTGGAGGVGG------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------TAGETGVTGGVGGIGG------------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------GRGGDGIDGGTGGAGGMG----------------
TH_3810|M.thermoresistible__bu      ----------------GSGVDGVDVVGGNPDG------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------AGLAGNAGLAGNAGLAG------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------TVALQPTPNQHLIVPTEQ------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -----AVGTGGTGGVVGDVGN-----------------------------
Rv3508|M.tuberculosis_H37Rv         -----AIGTGGTGGAVGSVGN-----------------------------
MMAR_1594|M.marinum_M               GTSGQSIGTGGDGGAGGDGGTGTTGADAAAGSGLGGDIGGTGGAGGAGGT
MUL_4367|M.ulcerans_Agy99           ---------GGVGAAS----------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -----EIYSGADGEATG---------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -------AGIGGTGGKGGAGGTG-----------------FAGGAGGAGG
Rv3508|M.tuberculosis_H37Rv         -------AGIGGTGGTGGVGGAGGAGAAAAAGSSATGGAGFAGGAGGEGG
MMAR_1594|M.marinum_M               GGSGGTDSGVGGSGGVGGVGGTGGQGGAGSDNSANAGVAGGAGGQGGAGG
MUL_4367|M.ulcerans_Agy99           ---------LGGDGG--------------------------HAGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------------QGTAGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------------------QGTEGGTGG
MSMEG_0868|M.smegmatis_MC2_155      -------ISAGGDGGS-------------------------ATGADSLGG
TH_3810|M.thermoresistible__bu      -------------------------------------------GTPGAHG
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------------NAGLAGNAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------------------------APAPPPVQA
                                                                                      

Mb3538|M.bovis_AF2122/97            QGGSSGAG-------------------------------------GTNGS
Rv3508|M.tuberculosis_H37Rv         AGGNSGVG-------------------------------------GTNGS
MMAR_1594|M.marinum_M               TGGAAGSGGTGSVAGADGSSGDGGTGGLGGDGGAGGTGSMGAVDGGTGGQ
MUL_4367|M.ulcerans_Agy99           EGLSGGFN--------------------------------------TGAA
Mflv_5091|M.gilvum_PYR-GCK          VGGIGGAG-------------------------------------STGAV
Mvan_1264|M.vanbaalenii_PYR-1       VGGVGGVG-------------------------------------ATGGA
MSMEG_0868|M.smegmatis_MC2_155      RGGTSWVQAG--------------------------------YGPTTGGK
TH_3810|M.thermoresistible__bu      ESHTPGVY--------------------------------------TDRQ
MAB_4284c|M.abscessus_ATCC_199      LAGNAG---------------------------------------LAGNA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                SAPQPKIS-------------------------------------VPEPV
                                                                                      

Mb3538|M.bovis_AF2122/97            GGAGGTGGQGGAGGAGGAGADNPTGIGGAGGTGGTG--------------
Rv3508|M.tuberculosis_H37Rv         GGAGGAGGKGGTGGAGGSGADNPTGAGFAGGAGGTG--------------
MMAR_1594|M.marinum_M               GASGGAGGQGGTGGAAGAGTGGIQGAGGQGGTGGTGGTGGTGGDGAESTD
MUL_4367|M.ulcerans_Agy99           GGIGGAGGAGGTG----------------GDSGGVG--------------
Mflv_5091|M.gilvum_PYR-GCK          GGVGGKGIQGGQG-------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGVGGKGIQGGQG-------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATG------------
TH_3810|M.thermoresistible__bu      G-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GLAGNAGLAGNAG-------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AAPKPLSPPVAAP-------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------GAAGAGGAGGA-IGTGGTGGAVGSVGNAGIG-----------
Rv3508|M.tuberculosis_H37Rv         --------GAAGAGGAGGA-TGTGGTGGVVGATGSAGIGGAGGRGGDGGD
MMAR_1594|M.marinum_M               PSLAGQAGGQGGTGGTGGA-AGQGGTGSVTGAEGSAGDGGTGGLGGDGGT
MUL_4367|M.ulcerans_Agy99           --------GVNGDGGAGGG-GGRGGDGGSSTSTS----------------
Mflv_5091|M.gilvum_PYR-GCK          --------LQGGKGGDGGA-GGKGGDADSMGSAG----------------
Mvan_1264|M.vanbaalenii_PYR-1       --------LQGGQGGDGGT-GGTGGDATSMGEAG----------------
MSMEG_0868|M.smegmatis_MC2_155      ------NTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSG---
TH_3810|M.thermoresistible__bu      ---------EDGEDGTGTG-------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------LAGNAGLAGN-AGLAGNAGLAGNAG----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------LPAAPPPAAPPLPEAPPIPAAPPVVP----------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----------------------------------------------GTGG
Rv3508|M.tuberculosis_H37Rv         GASGLGLGLSGFDGGQGGQGGAGGSAGAGGIN--------------GAGG
MMAR_1594|M.marinum_M               GADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGG
MUL_4367|M.ulcerans_Agy99           ----------------------------------------------GVGG
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------------ATGG
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------------ATGG
MSMEG_0868|M.smegmatis_MC2_155      ---------------------------------------------HGGAA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------LAGNAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------------------------------------VPVVV
                                                                                      

Mb3538|M.bovis_AF2122/97            TGGVGGAGGA-----------------------------------GAAAA
Rv3508|M.tuberculosis_H37Rv         AGGNGGDGGD-----------------------------------GATGA
MMAR_1594|M.marinum_M               TGGQGGTGGDGAESTDPTLAAQAGGQGGTGGTGGAAGQGGTGSTMGAEGS
MUL_4367|M.ulcerans_Agy99           AGGAGGNGGN------------------------------------AGFG
Mflv_5091|M.gilvum_PYR-GCK          KGGNGGNGGR-------------------------------------GGL
Mvan_1264|M.vanbaalenii_PYR-1       KGGNGGNGGR-------------------------------------GSL
MSMEG_0868|M.smegmatis_MC2_155      QGGNGGNGGN-----------------------------------GWVQA
TH_3810|M.thermoresistible__bu      IGGRGGNGGS----------------------------------------
MAB_4284c|M.abscessus_ATCC_199      LAGNAGLAGN-------------------------------------AGL
MLBr_01183|M.leprae_Br4923          -----------------------------------------------MPL
MAV_4827|M.avium_104                PPVPVPVPVR-------------------------------------IPV
                                                                                      

Mb3538|M.bovis_AF2122/97            AGSSATGGAGFAG----------------------GAG------------
Rv3508|M.tuberculosis_H37Rv         AGLGDNGGVGGDG----------------------GAGGAAGNGGNAGVG
MMAR_1594|M.marinum_M               SGDGGTGGLGGDGGAGADNTTTVSTGAQGATGGTGGAGGQGGTGGAAGTG
MUL_4367|M.ulcerans_Agy99           VSAGGTGGSAGDG----------------------GAG------------
Mflv_5091|M.gilvum_PYR-GCK          FGKGGNAGNGADG-------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       FGRGGNAGNGGNG-------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      YDPNGPAGTTIDK-------------------------------------
TH_3810|M.thermoresistible__bu      --SSGTHPMAEDG-------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AGNAGLAGNAAVAG------------------------------------
MLBr_01183|M.leprae_Br4923          FLNAEPQALTAAA-------------------------------------
MAV_4827|M.avium_104                PDPVSPPQLLAPPR------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -----GEGGAGGNSGVGGTNGSGGAG------------------------
Rv3508|M.tuberculosis_H37Rv         LTAKAGDGGAAGNGGNGGAGGAGGAGDN----------------------
MMAR_1594|M.marinum_M               TGGIQGAGGQGGTGGTGGTGGSGGDGTDNSTTPGAAGGAGGQGGTGGTGG
MUL_4367|M.ulcerans_Agy99           -------GGAGGVDGVGGASGNGGAA------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------GTGGAGGAGGTGGTGGAG------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------GTGGNGGNGGTGGTGGNG------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------GKAAGGNGGDGGFNGTGGAT------------------------
TH_3810|M.thermoresistible__bu      -------------EHVKALDGRPGLD------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------NAAVAGNAAVAGNAAVG------------------------
MLBr_01183|M.leprae_Br4923          ----------------NTLEGLSAAT------------------------
MAV_4827|M.avium_104                ------LSVPQPVQPPVRVPQPPSPP------------------------
                                                           .                          

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------NFNGGQ
MMAR_1594|M.marinum_M               AAGSGGTGSTMGAEGSSGDGGTGGLGGDGGEGGQGTTAWNPGDTGGQGAS
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -GAGGKGGTGGAGGSGADNPTGAGFAGGAGGTGGAAGAGGAG--------
Rv3508|M.tuberculosis_H37Rv         GGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGGAGGAGTL------
MMAR_1594|M.marinum_M               GGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGDGTDNSTTPG
MUL_4367|M.ulcerans_Agy99           -GAGGAGGSGIGAG-------IDGGAGGAGGTGGAAGFPGGG--------
Mflv_5091|M.gilvum_PYR-GCK          -GTGGTGGTG-----------GIGGAGSTGGTGGTGGTGGTG--------
Mvan_1264|M.vanbaalenii_PYR-1       -GTGGTGGTG-----------GIGGAGSTGGTGGTGGTGGTG--------
MSMEG_0868|M.smegmatis_MC2_155      ---GGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVN------
TH_3810|M.thermoresistible__bu      -----------------------------GGNGSHGGNGGHG--------
MAB_4284c|M.abscessus_ATCC_199      ---------------------GVLNTGVSGAIGGSSHVGGAIN-------
MLBr_01183|M.leprae_Br4923          ----------------------------VASNAAAAQLTTEI--------
MAV_4827|M.avium_104                ----------------------QVGGTVPQSPPQHQTPPGEGTP------
                                                                  .                   

Mb3538|M.bovis_AF2122/97            ---------------GATGTGGTGGVVGATGSA-GIGGAGGRGGDGGDG-
Rv3508|M.tuberculosis_H37Rv         ---GVGGSGGTGGDGGDAGSGGGGGFGGAAGKA-GGGGNGGRGGDGGDG-
MMAR_1594|M.marinum_M               AAGGAGGQGGTGGTGGAAGTGGTGSTMGAEGSS-GDGGSGGLGGDGGAGG
MUL_4367|M.ulcerans_Agy99           ---------------GTTGAWGTGGAGGAGGAG-GAGDHGGVGVNPGDS-
Mflv_5091|M.gilvum_PYR-GCK          ------------------GTGGTGGTGGTGGTG-GTGGKGGTGGTGGAG-
Mvan_1264|M.vanbaalenii_PYR-1       ------------------GTGGTGGTGGTGGTG-GTGGKGGTGGTGGDG-
MSMEG_0868|M.smegmatis_MC2_155      -----------------AGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG-
TH_3810|M.thermoresistible__bu      ---------------------GRGGFLGIGGSG-GWGGHGGNGGDTDAD-
MAB_4284c|M.abscessus_ATCC_199      -----------------ESLGGSGSVGGSTAVG--GGAHTGVGGGVSTG-
MLBr_01183|M.leprae_Br4923          ---------------------APPAADDVSILL--AHFFSGHGRQYQAH-
MAV_4827|M.avium_104                -----------------PKPDGPGNYGGGHVPTPGAGGSGGSGGGHVPT-
                                                         .     .            * *       

Mb3538|M.bovis_AF2122/97            -----ASGLGLGLSGFDGGQGGQGGDGGSAGAG--GINGAGGAGGDGGDG
Rv3508|M.tuberculosis_H37Rv         -----ASGLGLGLSGFDGGQGGQGGAGGSAGAG--GINGAGGAGGNGGDG
MMAR_1594|M.marinum_M               QGTTGTAGAGTGGQGASGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTG
MUL_4367|M.ulcerans_Agy99           -----------GTAGWAGGAGGAGGAGGSAAFN--GVNGAGGAGGNGGAG
Mflv_5091|M.gilvum_PYR-GCK          ------------------GTGGDGGTGGTGGTG-----GTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       ------------------GTGGTGGTGGTGGTG-----GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      ------------------GDGALGGNGGTGGVG----LGNGGKGGNGGNG
TH_3810|M.thermoresistible__bu      -------------------------------------------GGNGGDG
MAB_4284c|M.abscessus_ATCC_199      -----------------VGVGSHVGGGISESLG--------GSGSVGGST
MLBr_01183|M.leprae_Br4923          -------------------------------------------ASQGATN
MAV_4827|M.avium_104                -------------------------------------------PGAGGSG
                                                                                . *.  

Mb3538|M.bovis_AF2122/97            GDG-----------------------------------------ATGAAG
Rv3508|M.tuberculosis_H37Rv         GDG-----------------------------------------ATGAAG
MMAR_1594|M.marinum_M               GTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTGSTIGSAGTAG
MUL_4367|M.ulcerans_Agy99           GGG-----------------------------------------GAGASG
Mflv_5091|M.gilvum_PYR-GCK          GAG-----------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GAG-----------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GNG-------------------------------------------GTYV
TH_3810|M.thermoresistible__bu      GNG-----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AVG-----------------------------------------------
MLBr_01183|M.leprae_Br4923          HQD-----------------------------------------------
MAV_4827|M.avium_104                GSG-----------------------------------------------
                                      .                                               

Mb3538|M.bovis_AF2122/97            LGDNGGVGGDG----------------------GAGGAAGNGGNAGVGLT
Rv3508|M.tuberculosis_H37Rv         LGDNGGVGGDG----------------------GAGGAAGNGGNAGVGLT
MMAR_1594|M.marinum_M               DGGTGGLGGDGGTGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTG
MUL_4367|M.ulcerans_Agy99           IG-AGVAGGDG-------------------------GTGGTGGAAGT---
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      DPSHTGAGGNG----------------------GNGGAGRIRVNNGTATG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            AKAGDGGAAGNGGNGGAGGAGGAGDNNFN-------GGQGGAGGQGGQGG
Rv3508|M.tuberculosis_H37Rv         AKAGDGGAAGNGGNGGAGGAGGAGDNNFN-------GGQGGAGGQGGQGG
MMAR_1594|M.marinum_M               GIQGAGGQGGTGGTGGQGGTGGDGADSTDPTLAGQAGGQGGTGGTGGAAG
MUL_4367|M.ulcerans_Agy99           -----GGAAGTGGTGGAAGAAGS-------------AGDGGAGGAGGAGD
Mflv_5091|M.gilvum_PYR-GCK          -----DGTGGTGGTGGTGGQGGQ-------------GGQGGTGGTGGQGG
Mvan_1264|M.vanbaalenii_PYR-1       -----DGLGGTGGTGGTGGFGGQ-------------GGQGGTGGTGGQGG
MSMEG_0868|M.smegmatis_MC2_155      -----TATGGNGGNGGNGDADGHR------------GGKGGDGGEALIRA
TH_3810|M.thermoresistible__bu      ------GSAGRGGTGGLRGVFGIN------------GGNGRAG-------
MAB_4284c|M.abscessus_ATCC_199      ------GGAHTGVGGGVSTGVGVG-------------SHVGGGISESLGG
MLBr_01183|M.leprae_Br4923          --------LIQSLLTSSSAYAGT--------------ETANHDSL-----
MAV_4827|M.avium_104                -----GGHVPTPGTGGPGGTGGSG------------GGHVPTPGAGTPGG
                                                   .     *                            

Mb3538|M.bovis_AF2122/97            LGGASTTS-----------------------------------INANGGA
Rv3508|M.tuberculosis_H37Rv         LGGASTTS-----------------------------------INANGGA
MMAR_1594|M.marinum_M               QGGTGSTSGSEGSSGDGGTGGLGGDGGAGADNTTTVSAGAQGATGGTGGA
MUL_4367|M.ulcerans_Agy99           DGSAGVVS------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          LGGGGGTG------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       LGGVGGTG------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TVIGSNASG-----------------------------------TATGGD
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SGSVGG--------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                SGGGHLPFP-----------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGAGGG------------
Rv3508|M.tuberculosis_H37Rv         GGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGG------------
MMAR_1594|M.marinum_M               GGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAG
MUL_4367|M.ulcerans_Agy99           -GDPGTAGKAG---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGTLGATN---------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------GGFGGAAG------------KAGGGGNGGVGGDGGEG-----
Rv3508|M.tuberculosis_H37Rv         --------GGFGGAAG------------KAGGGGNGGVGGDGGEG-----
MMAR_1594|M.marinum_M               GAGGQGGTGGTGGAAGQGGTGSTMGSDGSSGDGGTGGLGGDGGEGGQGTT
MUL_4367|M.ulcerans_Agy99           ------------------------------GAGGAGGVGGN---------
Mflv_5091|M.gilvum_PYR-GCK          ------------------------------GQGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------GTGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155      ------------------------------GTGGAATIVAYNVVQAN---
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ------------------------ATGLGLD-------------------
Rv3508|M.tuberculosis_H37Rv         ------------------------ASGLGLG-------------------
MMAR_1594|M.marinum_M               GTAGAGTGGQGASGGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ------------LSGFAGGQGGQGGAGGNAG-------------------
Rv3508|M.tuberculosis_H37Rv         ------------LSGFDGGQGGQGGAGGSAG-------------------
MMAR_1594|M.marinum_M               TGGDGADSTDPTLAGQAGGQGGTGGTGGAAGQGGTGSVAGTDGSSGDGGT
MUL_4367|M.ulcerans_Agy99           --------------GVAGGVNGSGGAG-----------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------TGGQGGTGGTG-----------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------TGGQGGTGGTG-----------------------
MSMEG_0868|M.smegmatis_MC2_155      ---------PQASGTATDGHGGSGING-----------------------
TH_3810|M.thermoresistible__bu      -------------------LGGRGXXX-----------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------STAVGGGAHTG-----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------AGGING
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------AGGING
MMAR_1594|M.marinum_M               GGLGGHGGAGADNTTTVSAGAQGATGGTGGAGGTGGTGGAAGTGTGGIQG
MUL_4367|M.ulcerans_Agy99           -------------------------------------------------G
Mflv_5091|M.gilvum_PYR-GCK          -------------------------------------------------G
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------------------------G
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------------------------G
TH_3810|M.thermoresistible__bu      -------------------------------------------------X
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------------------VG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------------------------------G
                                                                                      

Mb3538|M.bovis_AF2122/97            AGGTGGTG------GAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFG-
Rv3508|M.tuberculosis_H37Rv         AGGAGGTG------GAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFG-
MMAR_1594|M.marinum_M               AGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGQGG
MUL_4367|M.ulcerans_Agy99           AGGAGGTG------GAGASGVPASVD----GGDGGAGGAGGAAGTGGSG-
Mflv_5091|M.gilvum_PYR-GCK          TGGTGGTG------GAGGD-----------GGLGGLGGFGGSGGTGGQG-
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGTG------GAGGD-----------GGLGGLGGFGGVGGTGGQG-
MSMEG_0868|M.smegmatis_MC2_155      HGGNGGQG------TIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDG-
TH_3810|M.thermoresistible__bu      GGGVG------------------------AAVRSGNGVFSGGGGTPSAG-
MAB_4284c|M.abscessus_ATCC_199      GGVNTGVG---------------------VGSHVGGGISESLGGSGSVG-
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AGSTP-------------------------GGSGGGHLPTPGAGTPGGG-
                                                                                      

Mb3538|M.bovis_AF2122/97            -------AGVPGDGGIGG--------------------------------
Rv3508|M.tuberculosis_H37Rv         -------AGVPGDGGDGGNAGFGA--------------------------
MMAR_1594|M.marinum_M               TGSTSGSAGSSGDGGTGGLGGDGGEGGQGTTGTAGAGTGGQGASGGAGGQ
MUL_4367|M.ulcerans_Agy99           --------GSAGNTGAGG--------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----------------TGGAGGAGGAGGAGDAGADGDPSID-------GG
Rv3508|M.tuberculosis_H37Rv         ------------GVPGDGGIGGTGGAGGAGGAGADGDPSID-------GG
MMAR_1594|M.marinum_M               GGTGGAAGTGTGGTQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGG
MUL_4367|M.ulcerans_Agy99           ----------------AGGAGGAGGSAASTGVNGDG-------------G
Mflv_5091|M.gilvum_PYR-GCK          ------------------GLGGPGGSTG---------------------G
Mvan_1264|M.vanbaalenii_PYR-1       ------------------GQGGPGGSTG---------------------G
MSMEG_0868|M.smegmatis_MC2_155      ------------VVNTTANAANPGSATGTATGG----------------D
TH_3810|M.thermoresistible__bu      -------------------FGVPTTIQFP---------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------GSTAVGGGAHTSAIN---------------DA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------LGGFGGGHAPAPGG----------------G
                                                                                      

Mb3538|M.bovis_AF2122/97            QGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGD-------
Rv3508|M.tuberculosis_H37Rv         QGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGD-------
MMAR_1594|M.marinum_M               QGGTGGTGGAAGQGGTGSTMGSAGTAGDGGTGGLGGHGGTGADNTTTVSA
MUL_4367|M.ulcerans_Agy99           AGGAGGVGGLGGDS--AATAGGGGAGGDGGKGGAGGAGVNGVG-------
Mflv_5091|M.gilvum_PYR-GCK          AGGAGGQAGTAGKG-----------GLFGGSGSAGKAGATGAA-------
Mvan_1264|M.vanbaalenii_PYR-1       AGGAGGQAGVAGKG-----------GLFGGSGSAGTAGVTGAS-------
MSMEG_0868|M.smegmatis_MC2_155      GGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEAS------
TH_3810|M.thermoresistible__bu      -AGSCTSRAVSREG-----------IMPSSRAASARAGAACAS-------
MAB_4284c|M.abscessus_ATCC_199      LGGSGSVGGSTAVG------------GGAHTSAINESMNSSIN-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                LGGGGGHAPAPGGG------------LGGFGGGHSGGGLGGLG-------
                                                                                      

Mb3538|M.bovis_AF2122/97            -------GDGFIGGSGGTG-----GTGGDAGAGGLANTGGTAGNAGIG--
Rv3508|M.tuberculosis_H37Rv         -------GDGFIGGSGGTG-----GTGGDAGVGGLANTGGTAGNAGIG--
MMAR_1594|M.marinum_M               GAQGATGGTGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGQGGTGGT
MUL_4367|M.ulcerans_Agy99           ---------GGDGGKGGTG-----GAGGAGGAGSDGIIPSNGGLG-----
Mflv_5091|M.gilvum_PYR-GCK          ---------GASGGKGAQG-----ATGAQGATGAQGATG-----------
Mvan_1264|M.vanbaalenii_PYR-1       ---------GASGGKGAQG-----ATGAQGATGAQGATG-----------
MSMEG_0868|M.smegmatis_MC2_155      --------NGGVAGNGGNA--LVMAAGTTGVATGNTATGGDGGAAT----
TH_3810|M.thermoresistible__bu      ------------------------STSRSRRSFCCSRA------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------ASHSSSMNESFGSSMG----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------GGHK--------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GTDSTDPTLVGQAGGQGGTGGTGGAAGQGGTGSVTGAEGSAGDGGSGGLG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -------------------------GAGGRGGDGGAGDS------GALSQ
Rv3508|M.tuberculosis_H37Rv         -------------------------GAGGRGGDGGAGDS------GALSQ
MMAR_1594|M.marinum_M               GHGGTGADNTTAVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQ
MUL_4367|M.ulcerans_Agy99           -------------------------GNGGNGGNGGQAFG-----------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            DGNGFAGGQGGQG-------------------------------------
Rv3508|M.tuberculosis_H37Rv         DGNGFAGGQGGQG-------------------------------------
MMAR_1594|M.marinum_M               GGTGGTGGQGGTGGTGTDSTDPTLAGQAGGQGGTGGTGGAAGSGGTGSTM
MUL_4367|M.ulcerans_Agy99           DGVGGAGGIGGKG-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          -ATGAAGKAGATG-------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -ATGASGAQGSAG-------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -TAGATGGAGGFSN------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -SHGAAGTGFEAQG------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GAEGSSGDGGTGGLGGDGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----GAGGNAGAGGINGAGGTGGTGGAGGDGAPATLIGGPDGGDGGQGG-
Rv3508|M.tuberculosis_H37Rv         ----GVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGD
MMAR_1594|M.marinum_M               AAGTGTGGTQGAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGT
MUL_4367|M.ulcerans_Agy99           -------GNAAIGTIVINGGVGGAGGSGG---------------------
Mflv_5091|M.gilvum_PYR-GCK          --------AAGAAGAAGSAGTTGAQGSAG---------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------SAGSAGVAGSAGTTGAQGSAG---------------------
MSMEG_0868|M.smegmatis_MC2_155      -------IAAIHGAITDSTAISGHGGAGN---------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------HAQGHASETAHTTLPGAEHH-----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GGQG----------------------------------------------
MMAR_1594|M.marinum_M               GGTGGAAGSGGTGSTMGAEGSSGDGGTGGLGGDGGTGGQGTTAVNPGDTG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----------------GAGFGSG----VAG--------------------
Rv3508|M.tuberculosis_H37Rv         ---------GIGGAGGNAGFGAG----VPGDGGIGGTGGAGGAGGAGAD-
MMAR_1594|M.marinum_M               GQGASGGAGGTGGTGGAAGTGTGGTQGAGGQGGTGGTGGQGGTGGDGTDN
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ---------------------------------------------AAGAG
Rv3508|M.tuberculosis_H37Rv         ----GDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAG
MMAR_1594|M.marinum_M               STTPGAAGGAGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDGGTGGLGGAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GNGGKG----------------GDGGTGGTG-------------------
Rv3508|M.tuberculosis_H37Rv         GNGGDGDGFI-----------GGSGGTGGTGGDAGVGGLANTGGTAGNAG
MMAR_1594|M.marinum_M               GTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAAGTG-TGGIQGAGGQGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----------------------GTNFAGGQGG------------------
Rv3508|M.tuberculosis_H37Rv         IGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGI-----
MMAR_1594|M.marinum_M               TGGAGGSGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGSGGTGSTMG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -------------------------------------------AGGRGGA
Rv3508|M.tuberculosis_H37Rv         --------------------------------------NGAGGTGGTGGA
MMAR_1594|M.marinum_M               AEGSSGDGGTGGLGGAGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGA
MUL_4367|M.ulcerans_Agy99           ----------------------------------------------LGGA
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------------TNGA
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------------TNGA
MSMEG_0868|M.smegmatis_MC2_155      -----------------------------------------------GGN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGNGANG-------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGG
MMAR_1594|M.marinum_M               AGTGTGGIQGAGGQGGTGGTGGQGGTGGDGAESTDPTLAGQAGGQGGTGG
MUL_4367|M.ulcerans_Agy99           TEDGVGG-------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          N--GANG-------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       N--GANG-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGKGADGWVQAYDPAGPVG-------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         TGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAAS-GD
MMAR_1594|M.marinum_M               TGGAAGQGGTGSVAGTDGSAGDGGTGGLGGHGGAGADNTTTVSAGAQGAT
MUL_4367|M.ulcerans_Agy99           -------------------------------------------------V
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -----------------------------------------------SKI
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            VGDNAAGGDGGNG-----------GAGGLGGGGGTGGTN-----------
Rv3508|M.tuberculosis_H37Rv         GGNGGAGGAGGNG-----------GAGGLGGGGGTGGTN-----------
MMAR_1594|M.marinum_M               GGTGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGTGGIGGTGTDSTD
MUL_4367|M.ulcerans_Agy99           GCAGGAGGNGGRG-------------DMLFTVGGSGGTG-----------
Mflv_5091|M.gilvum_PYR-GCK          -SQGAAGKAGATG-----------------TTGATGAAG-----------
Mvan_1264|M.vanbaalenii_PYR-1       -SQGAAGKAGATG-----------------TTGATGAAG-----------
MSMEG_0868|M.smegmatis_MC2_155      ANSSAVAGNGGDG-----------------GVNGTGGAS-----------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------GNGGLGGGGGN-
Rv3508|M.tuberculosis_H37Rv         --------------------------------------GNGGLGGGGGN-
MMAR_1594|M.marinum_M               PSQIAQAGGQGGTGGTGGAAGQGGTGSTMGSAGTAGDGGTGGLGGGGGTG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ------------------------GGAGGAGGTPTG--------------
Rv3508|M.tuberculosis_H37Rv         ------------------------GGAGGAGGTPTG--------------
MMAR_1594|M.marinum_M               ADNTTAVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGT
MUL_4367|M.ulcerans_Agy99           -------------------------GDGGGGGSASG--------------
Mflv_5091|M.gilvum_PYR-GCK          -------------------------EDGDAGSGGSG--------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------DAGDPGSEAVD--------------
MSMEG_0868|M.smegmatis_MC2_155      ------------------------GGDGGNGGNTSVWK------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -------------------------------------------SGTEGTG
Rv3508|M.tuberculosis_H37Rv         -------------------------------------------SGTEGTG
MMAR_1594|M.marinum_M               GGTGGIGGTGTDSTDPTLAGQAGGQGGTGGTGGAAGTGGTGSVTGTDGTA
MUL_4367|M.ulcerans_Agy99           -------------------------------------------SGTGGSG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------INGGAG
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------INGGAG
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------------------SGGQTAD
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GDGGDAGAGGNGGS------------------------------ATGVGN
Rv3508|M.tuberculosis_H37Rv         GDGGDAGAGGNGGS------------------------------ATGVGN
MMAR_1594|M.marinum_M               GDGGTGGLGGHGGAGADNTTTVSAGAQGATGGTGGAGGTGGTGGAAGTGT
MUL_4367|M.ulcerans_Agy99           GTGGVGGIGGDGKL------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GAGGAGGEGGEGGD------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GAGGAGGEGGEGGA------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GEHNTGGNGGNGGD------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGNGGDGGN--GGDGGNGAPGGFGGG----------AGAGGLGGSGAGGG
Rv3508|M.tuberculosis_H37Rv         GGNGGDGGN--GGDGGNGAPGGFGGG----------AGAGGLGGSGAGGG
MMAR_1594|M.marinum_M               GGTQGAGGQ--GGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGG
MUL_4367|M.ulcerans_Agy99           GGFGGDGGD--GGDGGFGVIGGQGGG----------GGFGGLGGTGAGG-
Mflv_5091|M.gilvum_PYR-GCK          GGKGGAGAE--GGAGGGGGAGGSGAG-----------GAGGAGGSGGSGG
Mvan_1264|M.vanbaalenii_PYR-1       GGAGGDGSE--GGAGGSGGAGGSGTG-----------GAGGAGGSGGSGG
MSMEG_0868|M.smegmatis_MC2_155      GSEPGPGGNGAGGAGGNGGTGGTTAGG---------SGNGGNGGNGGNGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            TDGDDGNGGSPGTDGS----------------------------------
Rv3508|M.tuberculosis_H37Rv         TDGDDGNGGSPGTDGS----------------------------------
MMAR_1594|M.marinum_M               AAGSGGTGSVTGTDGTAGDGGTGGLGGDGGAGADNTTTVSAGAQGATGGT
MUL_4367|M.ulcerans_Agy99           APSDKGINGEPGNPG-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK          SGGSGGSGGAAGDSDD----------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       SGGAGGSGGAAGDSD-----------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ADGTPGTAGTTGANNP----------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGAGGSGGTGGDGTDNSTTPG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               AAGGAGGQGGTGGTGGAAGQGGTGSTMGSDGSSGDGGTGGLGGDGGGAGQ
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GTTGTAGAGTGGQGASGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               TGGTGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTGSTMGAEGSSGD
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GGTGGLGGHGGAGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               TQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQ
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GGTGSTMGSAGTAGDGGTGGLGGGGGTGADNTTTVSAGAQGATGGTGGAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GQGGTGGAAGTGTGGIQGAGGQGGTGGTGGTGGIGGTGTDSTDPTLAGQA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------
Rv3508|M.tuberculosis_H37Rv         --------------------
MMAR_1594|M.marinum_M               GGQGGTGETGGAAGSGGTGS
MUL_4367|M.ulcerans_Agy99           --------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------
TH_3810|M.thermoresistible__bu      --------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------
MLBr_01183|M.leprae_Br4923          --------------------
MAV_4827|M.avium_104                --------------------