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M. tuberculosis H37Rv Rv3512 (PE_PGRS56)

annotation: PE-PGRS FAMILY PROTEIN
coordinates: 3941724 - 3944963
length: 1079
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Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3512PE_PGRS56-100% (1079)PE-PGRS FAMILY PROTEIN
M. tuberculosis H37RvRv3514PE_PGRS570.052.60% (1194) PE-PGRS family protein
M. tuberculosis H37RvRv3508PE_PGRS540.051.16% (1245) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3541PE_PGRS550.095.97% (1117) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-0.049.34% (835) triple helix repeat-containing collagen
M. leprae Br4923MLBr_01556infB1e-1035.83% (120) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_4284c-2e-6232.80% (561) hypothetical protein MAB_4284c
M. marinum MMMAR_1594-0.053.15% (1240) PE-PGRS family protein
M. avium 104MAV_4827-2e-2742.93% (184) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-0.041.61% (1091) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-5e-5144.67% (291) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.051.03% (1017) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-0.048.10% (842) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADEVSAR
MMAR_1594|M.marinum_M               MSYMSISPEIVSSAAGELANIGSTVSAANAAAAVATTELLAAGSDEVSTR
MUL_4367|M.ulcerans_Agy99           MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDEVSAA
MSMEG_0868|M.smegmatis_MC2_155      -----MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            IAALFGMYGLEYQAISAQVAAYHQQFVQTLRTGAASYMLAEAT------N
MMAR_1594|M.marinum_M               IAALFGANGVEYQAISAQIASFHDRFVAALNTGTSSYVWAEAT------N
MUL_4367|M.ulcerans_Agy99           IAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQE
MSMEG_0868|M.smegmatis_MC2_155      LAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            VEQNLLNLINAPTQTLLGRPLIGDGANATTPGGAGGDGGLLFGSGGNGAP
MMAR_1594|M.marinum_M               VEQNLLNAVNAPVQTLLGRPLIGNGANATTPGGAGGDGGLLYGSGGNGAA
MUL_4367|M.ulcerans_Agy99           LEQQALGVVNAPSMALFGRPSIGN--------------------------
MSMEG_0868|M.smegmatis_MC2_155      TDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GAPGQAGGAGGSAGLLGNGGSGGAGGTG-APGGNGGNAGWLYGRGGVGGA
MMAR_1594|M.marinum_M               GAPGQAGGAGGSAGLWGNGGSGGSGGIGGGTGGNGGSGGWLLGRGGIGGA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      LIPNAPTEPADMPGVWAVMAWAR---------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GGIGGGTGGAGGHAWLFGHGGTG---------------------------
MMAR_1594|M.marinum_M               GGTGGGSGGSGGGAWLFGDGGAGGMGGTGGSGGGFGGTGGHGGLLYGNGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1594|M.marinum_M               AGGAGATGQTGGSGGWAALWGRGGAGGAGGDNGGFAGGDGGHGGLLCGAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            ---GIGGGPGGNGGWLLGNGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGG
MMAR_1594|M.marinum_M               GDGGLGGGDGGNAGWLLGFGGHGGAGGDGGFAGGEGGNGGWLLGFGGHGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            AGGTGGGAGGTGGNAAWLLGGGGTGGAGGIGGGNGGHGGNGGWLLGNGGN
MMAR_1594|M.marinum_M               TGGIGGGTGGAGGAGGLVMGFGGHGGTGGIGGGAGGAGGQAALLFGHGGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGAGSTGTAGGGSGGT
MMAR_1594|M.marinum_M               GGAGGVGTAGGAGGAGGDGGNPGWLLGRAGSGGDGGAGGAATTVGATGGV
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GGDGGTGGRGGLLMGAGAGGHGGTGGAGGAGVDGGGAGG------AGGAG
MMAR_1594|M.marinum_M               GGHGGAGGRGGVLMGGGAGGDGGAGGAGADGSNGVGDGGNGATGGGGGVG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GNGGAGGQAALLFGRGGTGGAGGYGGDGGGGGDGFDGTMAGLGGTGGSGG
MMAR_1594|M.marinum_M               GDGGAGGQAALLFGCGGTGGHAGAGGAGGGGGTGADS----LTGIGGAGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            TGGDGGAPGNGGAGGAGQLLSHSGVAGASGKGGAGGTGGNGGAGSAGADA
MMAR_1594|M.marinum_M               DGGIGGASGQAGAGGAGNLFSHNGSRGHAGIGGDGGDGGTGGTGGEGTDA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            PAGSGAMGSTGFAGGAGGDGGNGGGSGA----------------------
MMAR_1594|M.marinum_M               AAGSGLTGGTGYAGGTGGTGGAGGNSGLGGTNGSGGHGGTGGTGGTGGTG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1594|M.marinum_M               GSGADNTTGIGGDGGQGGTGGDAGAGGAGGNSGFGGTGGTTGTHGDAGIG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            ------------------------------------------------SQ
MMAR_1594|M.marinum_M               GDGGDGGTGGTGGQGTDAAAGTGLTGGTGYAGGTGGAGGAGGNSGLGGTN
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GNGGNGGNGGTGGKGGTGGAGMNSLDP-----------------------
MMAR_1594|M.marinum_M               GSGGHGGTGGTGGTGGTGGSGADALDGSGASGHDGGDSGAGGDGGTGGAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1594|M.marinum_M               GNAGTGAGAAGNNGDGGAGGTGGNSGAQAGDGGAGAANTTIGGTGGAGGS
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1594|M.marinum_M               GGNIGAGGAGGQGGAAGTTSGVGGASGTSGTSGQSIGTGGDGGAGGDGGT
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1594|M.marinum_M               GTTGADAAAGSGLGGDIGGTGGAGGAGGTGGSGGTDSGVGGSGGVGGVGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            ---------------LLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAG
MMAR_1594|M.marinum_M               TGGQGGAGSDNSANAGVAGGAGGQGGAGGTGGAAGSGGTGSVAGADGSSG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            NGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTG
MMAR_1594|M.marinum_M               DGGTGGLGGDGGAGGTGSMGAVDGGTGGQGASGGAGGQGGTGGAAGAGTG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAG
MMAR_1594|M.marinum_M               GIQGAGGQGGTGGTGGTGGTGGDGAESTDPSLAGQAGGQGGTGGTGGAAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            AGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGA
MMAR_1594|M.marinum_M               QGGTGSVTGAEGSAGDGGTGGLGGDGGTGADNTTTVSAGAQGATGGTGGA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQ
MMAR_1594|M.marinum_M               GGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGDGAESTDPTLAAQ
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP
Rv3512|M.tuberculosis_H37Rv         ---------------------PQGADGNAGNGGDGGVGGNGGNGADNTTT
Mb3541|M.bovis_AF2122/97            DGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTT
MMAR_1594|M.marinum_M               AGGQGGTGGTGGAAGQGGTGSTMGAEGSSGDGGTGGLGGDGGAGADNTTT
MUL_4367|M.ulcerans_Agy99           -----------------------GVDGVAGTGQAGGAGGILWGNGGNGGL
MSMEG_0868|M.smegmatis_MC2_155      ------RQPMYSDPAMRTTVNPQAQLPVPTVASAVLDPTQIVNWLIYQPL
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------MSIIDFILNLFRDPVEAASYVADPEAAL
MAV_4827|M.avium_104                -------------------------------MNIVLGVSMAPSSIQMVVL
MLBr_01556|M.leprae_Br4923          ----------------------MAGKARVHELAKELGVTSKEVLARLNEQ
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --MVTFGGGATPTPTSLGAAAVDLSGT---SCGLICNGQDGTGQNGGILF
Mvan_1264|M.vanbaalenii_PYR-1       WYVVSFGGSGAPTPNNLAASLVDLSGT---SCGLICNGQDGTGQNGGILF
Rv3512|M.tuberculosis_H37Rv         AAAGTTGGAGGAGGAGGTGGTGGAAGTG--TGGQQGNGGNGGNGGTGGKG
Mb3541|M.bovis_AF2122/97            AAAGTTGGAGGAGGAGGTGGTGGAAGTG--TGGQQGNGGNGGNGGTGGKG
MMAR_1594|M.marinum_M               VSTGAQGATGGTGGAGGQGGTGGAAGTG--TGGIQGAGGQGGTGGTGGTG
MUL_4367|M.ulcerans_Agy99           GAAGANGGAGGSAGLIGTGGVGGAGGVG--AAGMTGGSGGAG-GGGGWLW
MSMEG_0868|M.smegmatis_MC2_155      HAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTADNPNGGTGGLLF
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQN
MAV_4827|M.avium_104                EGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQL
MLBr_01556|M.leprae_Br4923          GEFVKSASSTVEAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESL
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GNGGSG----------WNSDVVGMDGGNGGNGGLFG--------GNGGNG
Mvan_1264|M.vanbaalenii_PYR-1       GNGGSG----------WNSEIAGVSGGNGGNAGLFG--------GNGGNG
Rv3512|M.tuberculosis_H37Rv         GTGGDG-------ALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDG
Mb3541|M.bovis_AF2122/97            GTGGDG-------ALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDG
MMAR_1594|M.marinum_M               GSGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDG
MUL_4367|M.ulcerans_Agy99           GAGGSG-----------GAAGAGGSGGSGG--WLWGNAGQTAGAGVGGAG
MSMEG_0868|M.smegmatis_MC2_155      GDGGHG----------YDGSAAGLAGGNGGNAGLFG---------NGGNG
TH_3810|M.thermoresistible__bu      ---------------------VDGDGGSGGRTGLFS------KLSRGGDG
MAB_4284c|M.abscessus_ATCC_199      YYAAQP----------DGPSILSPSLLSPRDNDFLSHNDTDFASHNPIAS
MAV_4827|M.avium_104                SSIGVT----------WTDQLEAAALRDALAARRIDNVMLVSAFLAAAAL
MLBr_01556|M.leprae_Br4923          DQTLDR----------ALDKAVAGNGATTAAPVQVDHSAAVVPIVAGEGP
                                                                       .              

Mflv_5091|M.gilvum_PYR-GCK          GNGLGGGNGGNG------------GNAGAFALFG-NGGNGGNGGVGVVG-
Mvan_1264|M.vanbaalenii_PYR-1       GNGLGSGDGGNG------------GDAGLFSLFG-RGGNGGNGGVGIAG-
Rv3512|M.tuberculosis_H37Rv         GKGGNGGIGAAGTTG-----PVGTGASGGTGGSGGAGGTGGDGGAANGG-
Mb3541|M.bovis_AF2122/97            GKGGNGGIGAAGTTG-----PVGTGASGGTGGSGGAGGTGGDGGAANGG-
MMAR_1594|M.marinum_M               GTGGLGGDGGEGGQGTTAWNPGDTGGQGASGGAGGTGGTGGAAGTGTGG-
MUL_4367|M.ulcerans_Agy99           GAGGAGDAGDQGVSG------VAPGEAGAVGFAGGAGGAGGAGGNGVGGG
MSMEG_0868|M.smegmatis_MC2_155      GVGWAGLDGGNG---------------GSGGLLMGIGGAGGAGGVGADG-
TH_3810|M.thermoresistible__bu      GDGGLGGNGGHG------------------------GGTGIISLLSLAG-
MAB_4284c|M.abscessus_ATCC_199      GNQVMSPSGNVDSFN----------RGPLLDLSFGDLQFGNRDTTAIG--
MAV_4827|M.avium_104                AQNVGGAMGYER---------------TAVLLVEPDTATLAVVETSDGSI
MLBr_01556|M.leprae_Br4923          STAHREELAPPAGQP----------SEQPGVPLPGQQGTPAAPHPGHPGM
                                    .       .                                    .    

Mflv_5091|M.gilvum_PYR-GCK          --ATGAVGAPGVAGATGATG-------VTSGVVGGNGEDAVGYGATGAAG
Mvan_1264|M.vanbaalenii_PYR-1       --ATGAVGAPGVAGATGATG-------VTSNVTGGNGADAVGYGATGAAG
Rv3512|M.tuberculosis_H37Rv         TAGAGGAGGNGGKGGDGGAG-------VTSSTAGNSGGAGGSGGKGGDAG
Mb3541|M.bovis_AF2122/97            TAGAGGAGGNGGKGGDGGAG-------VTSSTAGNSGGAGGSGGKGGDAG
MMAR_1594|M.marinum_M               IQGAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAG
MUL_4367|M.ulcerans_Agy99           VNGAGGAGGAGGVGGGGGAGASG----VGAGVAGGDGGTGGAGGAAGVGG
MSMEG_0868|M.smegmatis_MC2_155      ----TSAHVDGGTGGTGGTG----------GGTGGTGGIGGTGG--GLFG
TH_3810|M.thermoresistible__bu      ---------NGGNGGNG---------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---DGAVAVGGSNSGPIASG---------------QGSTAVNGDVRDSNI
MAV_4827|M.avium_104                PDVYKQQIRAESYGDAAG---------------------------QLSAM
MLBr_01556|M.leprae_Br4923          PTGPHPGPAPKPGGRPPRVG-----------NNPFSSAQSVARPIPRPPA
                                                 .                                    

Mflv_5091|M.gilvum_PYR-GCK          AAGAAGAAGAAGAVGSAGAA-----GEAGETGTWG-NAGLP-GKAGDAGG
Mvan_1264|M.vanbaalenii_PYR-1       AAGAAGAAGKAGAVGSAGTA-----GSAGAPGVWG-NAGLP-GAAGAAGG
Rv3512|M.tuberculosis_H37Rv         AGGAGATPGANGIAGNGGDG---GDGAAGAVGISG-ATGAGDGGHGGTGA
Mb3541|M.bovis_AF2122/97            AGGAGATPGANGIAGNGGDG---GDGAAGAVGISG-ATGAGDGGHGGTGG
MMAR_1594|M.marinum_M               TGGTGSTMGAEGSSGDGGSGGLGGDGGAGGQGTTG-TAGAGTGGQGASGG
MUL_4367|M.ulcerans_Agy99           AAGTGGTGGAAGVAGTGGDG---GDGGAGGAGSDA-SLAGQAGFAGGSGG
MSMEG_0868|M.smegmatis_MC2_155      LLGHSGSTGAAGAAGNGGDG---GNGGFGYVLIAGPNVTVGSETRGGTGG
TH_3810|M.thermoresistible__bu      ---YRTTDNNALDGGHGGNG-----GNVGFFSLFN------------LGG
MAB_4284c|M.abscessus_ATCC_199      INADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTN
MAV_4827|M.avium_104                VAGLEKLESLPGGLLLVGSG----VDVAPLKQVLQTTTFLDVSVAEEPET
MLBr_01556|M.leprae_Br4923          PRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGG
                                                       .                              

Mflv_5091|M.gilvum_PYR-GCK          AGAVGAAGAAGTVG--------------------TAGATGGT--------
Mvan_1264|M.vanbaalenii_PYR-1       AGAIGTAGVAGAAG--------------------TAGATGGT--------
Rv3512|M.tuberculosis_H37Rv         AGGNGGTGGAGGSGIDGVG--GGTGGTGGNGGNGAIGGAGGD--------
Mb3541|M.bovis_AF2122/97            AGGNGGTGGAGGSGIDGVG--GGTGGTGGNGGNGAIGGAGGD--------
MMAR_1594|M.marinum_M               AGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQIA
MUL_4367|M.ulcerans_Agy99           AGGVGGSAGAGG-----------------------VNGSGGD--------
MSMEG_0868|M.smegmatis_MC2_155      AGGTGGQSTAAGPGKGGGG-------GGGGGGAILIGANGGTVDG-----
TH_3810|M.thermoresistible__bu      AGGWGGSGVDG------------------------VDVVGGN--------
MAB_4284c|M.abscessus_ATCC_199      INDSFNTDRSTNIG------------------------SGNT--------
MAV_4827|M.avium_104                ALARGAALAAANAP--------------------LFASSTAALAY-----
MLBr_01556|M.leprae_Br4923          GNYRGGGVGALPGG----------------GSGGFRGRPGGG--------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         -AGGSGNSGGNG--------------------------------------
Mb3541|M.bovis_AF2122/97            -AGGSGNSGGNG--------------------------------------
MMAR_1594|M.marinum_M               QAGGQGGTGGTGGAAGQGGTGSTIGSAGTAGDGGTGGLGGDGGTGADNTT
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------GTGANGGAG-----------------------GVGG
Mvan_1264|M.vanbaalenii_PYR-1       --------------GVGGNGGAG-----------------------QAGG
Rv3512|M.tuberculosis_H37Rv         -----------GIGGKGGNAGAGGAAGS-------------NGGTVGANG
Mb3541|M.bovis_AF2122/97            -----------GTGGKGGNAGAGGAAGS-------------NGGTVGANG
MMAR_1594|M.marinum_M               TVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGG
MUL_4367|M.ulcerans_Agy99           -------------GGAGAAGGAGGASAT----------------VAGSGG
MSMEG_0868|M.smegmatis_MC2_155      ----------HAIGGNGGNGGNGSTTAAG-----------------GNGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          VGGT--------------------GAAGAAG-------------------
Mvan_1264|M.vanbaalenii_PYR-1       IGGT--------------------GAAGAAG-------------------
Rv3512|M.tuberculosis_H37Rv         TGGD-------------------GGNGGAAG-------AATAGSNGGAGT
Mb3541|M.bovis_AF2122/97            TGGD-------------------GGNGGAAG-------AATAGSNGGAGT
MMAR_1594|M.marinum_M               TGGDGADSTDPTLAGQAGGQGGTGGTGGAAGQGGTGSTSGSEGSSGDGGT
MUL_4367|M.ulcerans_Agy99           VGGD-------------------GGAGGAAG--------------GGVG-
MSMEG_0868|M.smegmatis_MC2_155      TGGTG--------------RVIAEGTGSTAEG-------TATGGDGGHST
TH_3810|M.thermoresistible__bu      ------------------------PDGGTPG-------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------TNTEIG-------------------
MAV_4827|M.avium_104                ------------------------AQDPGTG-------------------
MLBr_01556|M.leprae_Br4923          ------------------------GHGGGGR-------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -------------------------------------------------G
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------------------------Q
Rv3512|M.tuberculosis_H37Rv         G------------------------------------------------S
Mb3541|M.bovis_AF2122/97            G------------------------------------------------S
MMAR_1594|M.marinum_M               GGLGGDGGAGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGTQG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      G-----------------------------------------------TG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          AGGLGETG---TTGGAGGVGGQ----------------------------
Mvan_1264|M.vanbaalenii_PYR-1       AGTAGETG---VTGGVGGIGGQ----------------------------
Rv3512|M.tuberculosis_H37Rv         AGGNGGTG---GRGGSGGAGGD----------------------------
Mb3541|M.bovis_AF2122/97            AGGNGGTG---GRGGSGGAGGD----------------------------
MMAR_1594|M.marinum_M               AGGQGGTG---GTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAG
MUL_4367|M.ulcerans_Agy99           AASLGGDG---GHAGAGGAGGE----------------------------
MSMEG_0868|M.smegmatis_MC2_155      IGGNGGIGSVYAYGNNGAVSGTATG-------------------------
TH_3810|M.thermoresistible__bu      AHGESHTP---------GVYTD----------------------------
MAB_4284c|M.abscessus_ATCC_199      SHNQANIG------------------------------------------
MAV_4827|M.avium_104                AVDQYSLPDYLYVPVDPEPGDD----------------------------
MLBr_01556|M.leprae_Br4923          PGQRGGAAGAFGRPGGAPRRGR----------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------GTAGGT
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------GTEGGT
Rv3512|M.tuberculosis_H37Rv         -----------------GIGGVGG---------------GKGGNGADGEV
Mb3541|M.bovis_AF2122/97            -----------------GIGGVGG---------------GKGGNGADGEV
MMAR_1594|M.marinum_M               QGGTGSTMGSDGSSGDGGTGGLGGDGGEGGQGTTGTAGAGTGGQGASGGA
MUL_4367|M.ulcerans_Agy99           ---------------------------------------GLSGGFNTGAA
MSMEG_0868|M.smegmatis_MC2_155      ---------------------------------------GRGGDGIDGGT
TH_3810|M.thermoresistible__bu      ----------------------------------------------RQGE
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------------------TSTSA
MAV_4827|M.avium_104                -------------------------------------------ELAYSAV
MLBr_01556|M.leprae_Br4923          -------------------------------------------KSKRQKR
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GGVGGIG-------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGVGGVG-------------------------------------------
Rv3512|M.tuberculosis_H37Rv         GGAGGAG-----------GSGPNTSPGGNGGQG-----------------
Mb3541|M.bovis_AF2122/97            GGAGGAG-----------GSGPNTSPGGNGGQG-----------------
MMAR_1594|M.marinum_M               GGTGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGDGADSTDPTLAGQ
MUL_4367|M.ulcerans_Agy99           GGIGGAG-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGAGGMG-------------------------------------------
TH_3810|M.thermoresistible__bu      DGEDGTG-------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGSAAVG-------------------------------------------
MAV_4827|M.avium_104                GEEDAES-------------------------------------------
MLBr_01556|M.leprae_Br4923          QEYDSMQAP-----------------------------------------
                                        .                                             

Mflv_5091|M.gilvum_PYR-GCK          -----GAGSTG------------AVGGVGGKGIQGGQ-GLQGGKG-----
Mvan_1264|M.vanbaalenii_PYR-1       -----GVGATG------------GAGGVGGKGIQGGQ-GLQGGQG-----
Rv3512|M.tuberculosis_H37Rv         --GQGGSGGAGGAAGAGGAG--GGANGTAGNGGQGGA-GGTGGAGAASSA
Mb3541|M.bovis_AF2122/97            --GQGGSGGAGGAAGAGGAG--GGANGTAGNGGQGGA-GGTGGAGAASSA
MMAR_1594|M.marinum_M               AGGQGGTGGTGGAAGQGGTGSVAGTDGSSGDGGTGGL-GGHGGAGADNTT
MUL_4367|M.ulcerans_Agy99           -----GAGGTGGDSG--------GVGGVNGDGGAGGG-GGRGGDGGSSTS
MSMEG_0868|M.smegmatis_MC2_155      ---EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGG
TH_3810|M.thermoresistible__bu      -------------------------TGIGGRGGNGGS-------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------GNAGLAGNAGLAGN-------------
MAV_4827|M.avium_104                -----------------------PTVVIEKLFLPEDS-------------
MLBr_01556|M.leprae_Br4923          -----------------------VVGGVRLPHGNGETIRLARGASLSDFA
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -----------GDGGAGGKGGDA----------------------DSMG-
Mvan_1264|M.vanbaalenii_PYR-1       -----------GDGGTGGTGGDA----------------------TSMG-
Rv3512|M.tuberculosis_H37Rv         TN--------GGSGGAGGTGGDG--------------------GSGGAGG
Mb3541|M.bovis_AF2122/97            TN--------GGSGGAGGTGGAG--------------------GTGGAGG
MMAR_1594|M.marinum_M               TVSAGAQGATGGTGGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGG
MUL_4367|M.ulcerans_Agy99           TS---------GVGGAGGAGGNG--------------------GNAGFG-
MSMEG_0868|M.smegmatis_MC2_155      KASG------TAKAGHGGKASDG--------------------GKGGNGG
TH_3810|M.thermoresistible__bu      ------------SSGTHPMAEDG---------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------AGLAGNAGLAG---------------------------
MAV_4827|M.avium_104                ----------EPRRRPVLLVGSG---------------------------
MLBr_01556|M.leprae_Br4923          EKIDAN-----PAALVQALFNLG---------------------------
                                                          .                           

Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------------SAGA
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------------EAGA
Rv3512|M.tuberculosis_H37Rv         TGG--------------------------------------------AGG
Mb3541|M.bovis_AF2122/97            DGVGGAG-----------GGNGGHGGDAGDGGNGANGNNRSSGSFLAAGG
MMAR_1594|M.marinum_M               TGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGQGGTGSTSGSAGSSGDGG
MUL_4367|M.ulcerans_Agy99           ---------------------------------------------VSAGG
MSMEG_0868|M.smegmatis_MC2_155      D-----------------------------------------ALVMAAGA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------LAVVGI
MLBr_01556|M.leprae_Br4923          ---------------------------------------------EMVTA
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          TGGKGGNGGNGGR----------------GGLFG----------------
Mvan_1264|M.vanbaalenii_PYR-1       TGGKGGNGGNGGR----------------GSLFG----------------
Rv3512|M.tuberculosis_H37Rv         TGGAAGDGGQGGQ----------------GGAGG----------------
Mb3541|M.bovis_AF2122/97            TGGAAGDGGQGGQ----------------GGAGG----------------
MMAR_1594|M.marinum_M               TGGLGGDGGEGGQGTTGTAGAGTGGQGASGGAGGQGGTGGAAGTGTGGTQ
MUL_4367|M.ulcerans_Agy99           TGGSAGDGGAGGG---------------AGGVDGVG--------------
MSMEG_0868|M.smegmatis_MC2_155      TGVATGNTAIGGN----------------GGAAS----------------
TH_3810|M.thermoresistible__bu      EHVKALDGRPGLD-------------------------------------
MAB_4284c|M.abscessus_ATCC_199      NAGLAGNAGLAGN-------------------------------------
MAV_4827|M.avium_104                SAVLALEIALAIG-------------------------------------
MLBr_01556|M.leprae_Br4923          TQSVGDETLELLG-------------------------------------
                                          :                                           

Mflv_5091|M.gilvum_PYR-GCK          -KGGNAGNGADGGTGGAGGA------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -RGGNAGNGGNGGTGGNGGN------------------------------
Rv3512|M.tuberculosis_H37Rv         GAGGQGGAGGAGGTGGNGGN------------------------------
Mb3541|M.bovis_AF2122/97            GAGGQGGAGGAGGTGGNGGN------------------------------
MMAR_1594|M.marinum_M               GAGGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGG
MUL_4367|M.ulcerans_Agy99           GASGNGGAAGAGGAGGSGIG------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ANGAVGGNGGFTNIAAIHGS------------------------------
TH_3810|M.thermoresistible__bu      --GGNGSHGGNGGHGGR---------------------------------
MAB_4284c|M.abscessus_ATCC_199      --AGLAGNAGLAGNAGLAGN------------------------------
MAV_4827|M.avium_104                --IRTTGTVALQPTPNQHLIVP----------------------------
MLBr_01556|M.leprae_Br4923          --SEMNYNVQVVSPEDEDRELLEP--------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------------GGTGGTGGA
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------------------GGTGGTGGN
Rv3512|M.tuberculosis_H37Rv         ---------------------------------------ITGGTAGTAGA
Mb3541|M.bovis_AF2122/97            ---------------------------------------ITGGTAGTAGA
MMAR_1594|M.marinum_M               TGSTMGSAGTAGDGGTGGLGGHGGTGADNTTTVSAGAQGATGGTGGAGGQ
MUL_4367|M.ulcerans_Agy99           ----------------------------------------AGIDGGAGGA
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------------ITDSSATSGHGGA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          G--GTGGTGGTG-----GIGGAGSTG--------GTG-------------
Mvan_1264|M.vanbaalenii_PYR-1       G--GTGGTGGTG-----GIGGAGSTG--------GTG-------------
Rv3512|M.tuberculosis_H37Rv         A--GNGGAAGKG-----GAGGQGGTG-------GGTG-------------
Mb3541|M.bovis_AF2122/97            A--GNGGAAGKG-----GAGGQGGTG-------GGTG-------------
MMAR_1594|M.marinum_M               G--GTGGAAGTGTGGTQGAGGQGGTGGTGG--QGGTGGTGTDSTDPTLVG
MUL_4367|M.ulcerans_Agy99           G--GTGGAAGFP-------GGGGTTG------AWGTG-------------
MSMEG_0868|M.smegmatis_MC2_155      AQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNG-------------
TH_3810|M.thermoresistible__bu      ------------------------------------G-------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ---GTGGTGGTGGT-GGTGG------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---GTGGTGGTGGT-GGTGG------------------------------
Rv3512|M.tuberculosis_H37Rv         ---GQGGAGGDGGA-GGTGGDRTVGGGTVPAGSGG---------------
Mb3541|M.bovis_AF2122/97            ---GQGGAGGDGGA-GGTGGDRTVGGGTVPAGSGG---------------
MMAR_1594|M.marinum_M               QAGGQGGTGGTGGA-AGQGGTGSVTGAEGSAGDGGSGGLGGHGGTGADNT
MUL_4367|M.ulcerans_Agy99           ---GAGGAGGAGGA-GDHGGVGVNPGDSGTAGWAG---------------
MSMEG_0868|M.smegmatis_MC2_155      ---GDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG-------------
TH_3810|M.thermoresistible__bu      ---GFLGIGGS---------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --AGLAGNAGLAGN------------------------------------
MAV_4827|M.avium_104                ---TEQAPAPPP--------------------------------------
MLBr_01556|M.leprae_Br4923          FDLTYGEDQGDEDELQVRPPVVT---------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----------TGGTGGTGG-----------------------TGGKGGTG
Mvan_1264|M.vanbaalenii_PYR-1       ----------TGGTGGTGG-----------------------TGGKGGTG
Rv3512|M.tuberculosis_H37Rv         -------QGGNAGGGGAGGQGGAD----------------GGSGGDGGDA
Mb3541|M.bovis_AF2122/97            -------QGGNAGGGGAGGQGGAD----------------GGSGGDGGDA
MMAR_1594|M.marinum_M               TAVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQG
MUL_4367|M.ulcerans_Agy99           ---------GAGGAGGAGGSAAFN-----------------GVNGAGGAG
MSMEG_0868|M.smegmatis_MC2_155      -------QTDTGGNGGRGGDGGTFVN--------------AGANGNGGAG
TH_3810|M.thermoresistible__bu      -------------------------------------------GGWGGHG
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------------AGLAGNA
MAV_4827|M.avium_104                ------------------------------------------VQASAPQP
MLBr_01556|M.leprae_Br4923          ------------------------------------------VMGHVDHG
                                                                                .     

Mflv_5091|M.gilvum_PYR-GCK          GTGGA-------------------GGTGGDGGTG---------------G
Mvan_1264|M.vanbaalenii_PYR-1       GTGGD-------------------GGTGGTGGTG---------------G
Rv3512|M.tuberculosis_H37Rv         GTGGN-------------------GGNGGNRNSG--------------NG
Mb3541|M.bovis_AF2122/97            GTGGN-------------------GGNGGNRNSG--------------NG
MMAR_1594|M.marinum_M               GTGGTGTDSTDPTLAGQAGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDGG
MUL_4367|M.ulcerans_Agy99           GNGGA-------------------GGGGGAGASG--------------IG
MSMEG_0868|M.smegmatis_MC2_155      GAGGVS------------------EGEGGTGGHG---------------G
TH_3810|M.thermoresistible__bu      GNGGD---------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GLAGN---------------------------------------------
MAV_4827|M.avium_104                KISVP---------------------------------------------
MLBr_01556|M.leprae_Br4923          KTRLLDTIR---------------------------------------KA
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          TGGTGGTG-------------------GTGGTGGTGGAG-----------
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGTG-------------------GTGGTGGTGGAG-----------
Rv3512|M.tuberculosis_H37Rv         TGGAGGNG----------------GGGANGGAGGAGGSG-----------
Mb3541|M.bovis_AF2122/97            TGGAGGNG----------------GGGANGGAGGAGGSG-----------
MMAR_1594|M.marinum_M               TGGLGGDGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAAGTGTGGTQ
MUL_4367|M.ulcerans_Agy99           AGVAGGDG-------------------GTGGTGGAAGTG-----------
MSMEG_0868|M.smegmatis_MC2_155      DGGRGGDG-------------------ALGGNGGTGGVG-----------
TH_3810|M.thermoresistible__bu      TDADGGNG-------------------GDGGNGGSAGRG-----------
MAB_4284c|M.abscessus_ATCC_199      AGLAGNAG-------------------LAGNAGLAGNAG-----------
MAV_4827|M.avium_104                EPVAAPKP-------------------LSPPVAAPLPAAP----------
MLBr_01556|M.leprae_Br4923          NVREAEAG-------------------GITQHIGAYQVG-----------
                                        .                             .   .           

Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------DGTGGTGGTGGTGGQG
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------DGLGGTGGTGGTGGFG
Rv3512|M.tuberculosis_H37Rv         -------------------------------GGTGGNGGAGGDAGDAGNG
Mb3541|M.bovis_AF2122/97            -------------------------------GGTGGNGGAGGDAGDAGNG
MMAR_1594|M.marinum_M               GAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGSG
MUL_4367|M.ulcerans_Agy99           --------------------------------GAAGTGGTGGAAGAAGSA
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------LGNGGKGGNGGNGGNGGTY
TH_3810|M.thermoresistible__bu      --------------------------------------GTGGLRGVFGIN
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------LAGNAGLAGNAGLAGNA
MAV_4827|M.avium_104                ---------------------------------PPAAPPLPEAPPIPAAP
MLBr_01556|M.leprae_Br4923          -------------------------------VDLDGSERLITFIDTPGHE
                                                                                   .  

Mflv_5091|M.gilvum_PYR-GCK          GQGGQGGTGGTGGQGGLGGGGGTGGQG-----------------------
Mvan_1264|M.vanbaalenii_PYR-1       GQGGQGGTGGTGGQGGLGGVGGTGGTG-----------------------
Rv3512|M.tuberculosis_H37Rv         GNGNGTGNGGNGGNGGIAGMGGNGGAG-----------------------
Mb3541|M.bovis_AF2122/97            GNGNGTGNGGNGGNGGIAGMGGNGGAG-----------------------
MMAR_1594|M.marinum_M               GTGSTMGAEGSSGDGGTGGLGGDGGTGGQGTTAVNPGDTGGQGASGGAGG
MUL_4367|M.ulcerans_Agy99           GDGGAGGAGGAGDDGSAGVVSGDPGTAG----------------------
MSMEG_0868|M.smegmatis_MC2_155      VDPSHTGAGGNGGNGGAGRIRVNNGTATG---------------------
TH_3810|M.thermoresistible__bu      GGNGRAGLGGRGXXX-----------------------------------
MAB_4284c|M.abscessus_ATCC_199      GLAGNAGLAGNAAVAGNAAVAGNAAVAG----------------------
MAV_4827|M.avium_104                PVVPVPVVVPPVPVPVPVRIPVPDPVS-----------------------
MLBr_01556|M.leprae_Br4923          AFTAMRARGAKATDIAILVVAADDGVMP----------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----------GTGGTGGQGGTG-GTGGTGGTGGTGG--------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------GTGGTGGQGGTG-GTGGTGGTGGTGG--------------
Rv3512|M.tuberculosis_H37Rv         -------TGSGNGGNGGSGGNG-GNAGMGGNSGTGS--------------
Mb3541|M.bovis_AF2122/97            -------TGSGNGGNGGSGGNG-GNAGMGGNSGTGS--------------
MMAR_1594|M.marinum_M               TGGTGGAAGTGTGGTQGAGGQG-GTGGTGGQGGTGGDGTDNSTTPGAAGG
MUL_4367|M.ulcerans_Agy99           ----------KAGGAGGAGGVG-GNGVAGGVNGSGG--------------
MSMEG_0868|M.smegmatis_MC2_155      ---------TATGGNGGNGGNGDADGHRGGKGGDGGE------------A
TH_3810|M.thermoresistible__bu      ----------XGGGVGAAVRSG--NGVFSGGGGTPSAGFG----------
MAB_4284c|M.abscessus_ATCC_199      -----------NAAVGGVLNTG-VSGAIGGSSHVGG--------------
MAV_4827|M.avium_104                -----------PPQLLAPPRLSVPQPVQPPVRVPQP--------------
MLBr_01556|M.leprae_Br4923          -----QTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRG----------
                                                    .                                 

Mflv_5091|M.gilvum_PYR-GCK          ------AGGDGGLGGLGGFG------------------GSGGTGG-----
Mvan_1264|M.vanbaalenii_PYR-1       ------AGGDGGLGGLGGFG------------------GVGGTGG-----
Rv3512|M.tuberculosis_H37Rv         --GDGGAGGNGGAAGTGGTG------------GDGGLTGTGGTGG-----
Mb3541|M.bovis_AF2122/97            --GDGGAGGNGGAAGTGGTG------------GDGGLTGTGGTGG-----
MMAR_1594|M.marinum_M               AGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDGGTGGLGGAGGTGGQGTTA
MUL_4367|M.ulcerans_Agy99           ------AGGAGGAGGTGGAG----------------ASGVPASVD-----
MSMEG_0868|M.smegmatis_MC2_155      LIRATVIGSNASGTATGGDG------------------GNGGTLG-----
TH_3810|M.thermoresistible__bu      ---------------------------------------VPTTIQ-----
MAB_4284c|M.abscessus_ATCC_199      -------AINESLGGSGSVG------------------GSTAVGG-----
MAV_4827|M.avium_104                -------PSPPQVGGTVPQS-------------------PPQHQT-----
MLBr_01556|M.leprae_Br4923          ------QLTEYGLVAEDFGG-------------DTMFIDISAKVG-----
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -------------------------------------QGGLGGPGGSTGG
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------------QGGQGGPGGSTGG
Rv3512|M.tuberculosis_H37Rv         ----------------------------------SGGTGGDGGNGGNG--
Mb3541|M.bovis_AF2122/97            ----------------------------------SGGTGGDGGNGGNGGN
MMAR_1594|M.marinum_M               VNPGDTGGQGASGGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGAGGSGGT
MUL_4367|M.ulcerans_Agy99           -----------------------------------GGDGGAGGAGGAAG-
MSMEG_0868|M.smegmatis_MC2_155      ------------------------------------ATNGTGGAATIVAY
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------TNIEALLEAVLL
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -------------AGGAGGQAGTAGKGGLFG-----GSGSAGKAGATGAA
Mvan_1264|M.vanbaalenii_PYR-1       -------------AGGAGGQAGVAGKGGLFG-----GSGSAGTAGVTGAS
Rv3512|M.tuberculosis_H37Rv         -ADNTANMTAQ--AGGDGGNGGDGGFGGGAG-----AGGGGLTAGANGTG
Mb3541|M.bovis_AF2122/97            GADNTANMTAQ--AGGDGGNGGDGGFGGGAG-----AGGGGLTAGANGTG
MMAR_1594|M.marinum_M               GGDGTDNSTTPGAAGGAGGQGGTGGTGGAAG-----SGGTGSTMGAEGSS
MUL_4367|M.ulcerans_Agy99           -------------TGGSGGSAGNTGAGGAGG-----AGGAGGSAASTGVN
MSMEG_0868|M.smegmatis_MC2_155      NVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAG
TH_3810|M.thermoresistible__bu      ------------FPAGSCTSRAVSREGIMPS-----SRAASARAGAACAS
MAB_4284c|M.abscessus_ATCC_199      ----------GAHTGVGGGVSTGVGVGSHVG------GGISESLGGSGSV
MAV_4827|M.avium_104                -------------PPGEGTPPKPDGPGNYGG-----GHVPTPGAGGSGGS
MLBr_01556|M.leprae_Br4923          TADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVA
                                                                                .     

Mflv_5091|M.gilvum_PYR-GCK          G--ASGGKGAQGATGAQG--------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       G--ASGGKGAQGATGAQG--------------------------------
Rv3512|M.tuberculosis_H37Rv         GQGGAGGDGGNGAIGGHGPLTDDPG-------------------------
Mb3541|M.bovis_AF2122/97            GQGGAGGDGGNGAIGGHGPLTDDPG-------------------------
MMAR_1594|M.marinum_M               GDGGTGGLGGAGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAAGTGT
MUL_4367|M.ulcerans_Agy99           GDGGAGGAGGVGGLGGDSAATAGGG-------------------------
MSMEG_0868|M.smegmatis_MC2_155      GNGGDGIDGGLGGNGGDGVVNTTAN-------------------------
TH_3810|M.thermoresistible__bu      STSRSRRSFCCSRA------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGSTAVGGGAHTGVGGGVSTGVGVG-------------------------
MAV_4827|M.avium_104                GGGHVPTPGAGGSGGSGGGHVPTPG-------------------------
MLBr_01556|M.leprae_Br4923          GDAYGRVRRMVDEHGVDIEAALPSS-------------------------
                                    .                                                 

Mflv_5091|M.gilvum_PYR-GCK          ----------ATGAQGATGATGA---------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------ATGAQGATGATGA---------------------------
Rv3512|M.tuberculosis_H37Rv         -------GNGGTGGNGGTGGTGG---------------------------
Mb3541|M.bovis_AF2122/97            -------GNGGTGGNGGTGGTGG---------------------------
MMAR_1594|M.marinum_M               GGIQGAGGQGGTGGTGGQGGTGGDGAESTDPTLAGQAGGQGGTGGTGGAA
MUL_4367|M.ulcerans_Agy99           ----------GAGGDGGKGGAGG---------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------AANPGSATGTATGGDGGKATG-----------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------SHVGGGISESLGG---------------------------
MAV_4827|M.avium_104                -----------TGGPGGTGGSGG---------------------------
MLBr_01556|M.leprae_Br4923          --------PVQVIGFTSVPGAGDNFLVVD---------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         -----------------AGIGSLG--------------------------
Mb3541|M.bovis_AF2122/97            -----------------AGIGSLG--------------------------
MMAR_1594|M.marinum_M               GQGGTGSVAGTDGSAGDGGTGGLGGHGGAGADNTTTVSAGAQGATGGTGG
MUL_4367|M.ulcerans_Agy99           -----------------AGVNGVG--------------------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------TASQGGNG--------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------AGKAGATGAAGAAGAAGSA-----------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------SGAQGSAGSAGSAGVAGSA-----------
Rv3512|M.tuberculosis_H37Rv         ---------------GGTGGDGGNG---GNGGTGGEGGE-----------
Mb3541|M.bovis_AF2122/97            ---------------GGTGGDGGNGGTGGNGGTGGEGGE-----------
MMAR_1594|M.marinum_M               AGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQIA
MUL_4367|M.ulcerans_Agy99           ------------------GGDGGKGGTGGAGGAGGAGSD-----------
MSMEG_0868|M.smegmatis_MC2_155      ---------------GPSWVQSGYGSTLGGNATGTATAG-----------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------SGSVGGSTAVGGGAHTGVG-----------
MAV_4827|M.avium_104                ----------------------GHVPTPGAGTPGGSGGG-----------
MLBr_01556|M.leprae_Br4923          ---------------EDRIARQIADRRSARKRNALAARSRKRISLEDLDS
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -----GTTGAQGSAGTNG------------ANGANGSQ------------
Mvan_1264|M.vanbaalenii_PYR-1       -----GTTGAQGSAGTNG------------ANGANGSQ------------
Rv3512|M.tuberculosis_H37Rv         ----VGGAGGTGGAAGNG------------GDGGTGGTGGGD--------
Mb3541|M.bovis_AF2122/97            ----VGGAGGTGGAAGNG------------GDGGTGGTGGGD--------
MMAR_1594|M.marinum_M               QAGGQGGTGGTGGAAGQGGTGSTMGSAGTAGDGGTGGLGGGGGTGADNTT
MUL_4367|M.ulcerans_Agy99           -----GIIPSNGGLGGNG------------GNGGNGGQAFGDG-------
MSMEG_0868|M.smegmatis_MC2_155      ----KGGEASNGGVAGNGG------NALVMAAGTTGVATGNTATGGD---
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----GGVNTGVGVGSHVG-------------------------------
MAV_4827|M.avium_104                ------HLPFPGAGSTPG--------------------------------
MLBr_01556|M.leprae_Br4923          ALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDR-------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ------------------------------------GAAGKAGATGTTGA
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------GAAGKAGATGTTGA
Rv3512|M.tuberculosis_H37Rv         ------------------------------------GGAGGTGGTGGTGG
Mb3541|M.bovis_AF2122/97            ------------------------------------GGAGGTGGTGGTGG
MMAR_1594|M.marinum_M               AVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGTGG
MUL_4367|M.ulcerans_Agy99           -----------------------------------VGGAGGIGGKGGNAA
MSMEG_0868|M.smegmatis_MC2_155      -----------------------------------GGAATTAGATGGAGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------GGISESLGGSGS
MAV_4827|M.avium_104                ------------------------------------GSGGGHLPTPGAGT
MLBr_01556|M.leprae_Br4923          ------------------------------------GVGGITETNVNLAS
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          TG------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       TG------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         LGDP----------------------------------------------
Mb3541|M.bovis_AF2122/97            LGDP----------------------------------------------
MMAR_1594|M.marinum_M               IGGTGTDSTDPTLAGQAGGQGGTGGTGGAAGTGGTGSVTGTDGTAGDGGT
MUL_4367|M.ulcerans_Agy99           IGTIVIN-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      FSNIAAIH------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VG------------------------------------------------
MAV_4827|M.avium_104                PG------------------------------------------------
MLBr_01556|M.leprae_Br4923          ASDAIIIG------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ---------------------------AAGEDGDAGSGGSGIN-------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------------AAGDAGDPGSEAVDIN-------
Rv3512|M.tuberculosis_H37Rv         -----------------------RVGGSGGDGGTGGSGGAAGN-------
Mb3541|M.bovis_AF2122/97            -----------------------RVGGSGGDGGTGGSGGAAGN-------
MMAR_1594|M.marinum_M               GGLGGHGGAGADNTTTVSAGAQGATGGTGGAGGTGGTGGAAGTGTGGTQG
MUL_4367|M.ulcerans_Agy99           -------------------------GGVGGAGGSGGLGGATED-------
MSMEG_0868|M.smegmatis_MC2_155      -------------------------GAITDSTAISGHGGAGNG-------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------GSTAVGGGAHTSAIN-------
MAV_4827|M.avium_104                ----------------------------GGLGGFGGGHAPAPG-------
MLBr_01556|M.leprae_Br4923          ----------------------FNVRAEGKATELASREGVEIR-------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------GGNGGNAGAGGN
Mb3541|M.bovis_AF2122/97            --------------------------------------GGNGGNAGAGGN
MMAR_1594|M.marinum_M               AGGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGSGGT
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1594|M.marinum_M               GSVTGTDGTAGDGGTGGLGGDGGAGADNTTTVSAGAQGATGGTGGAGGQG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -------------------GGAGGAGGAGG--EGGEGGD--------GGK
Mvan_1264|M.vanbaalenii_PYR-1       -------------------GGAGGAGGAGG--EGGEGGA--------GGA
Rv3512|M.tuberculosis_H37Rv         -----------------GNGGTGGAGGIGG--TGGNGGD--AEPGVPPGA
Mb3541|M.bovis_AF2122/97            -----------------GNGGTGGAGGIGG--TGGNGGD--AEPGVPPGA
MMAR_1594|M.marinum_M               GTGGAAGTGTGGIQGAGGQGGTGGAGGSGG--TGGDGTDNSTTPGAAGGA
MUL_4367|M.ulcerans_Agy99           -----------------GVGGVGCAGGAGG--NGG-RGDMLFTVGGSGGT
MSMEG_0868|M.smegmatis_MC2_155      -----------------GNGGKGADGWVQAYDPAGPVGSKIANSSAVAGN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------DALGGSGSVGGSTAVGGGAHTSAINESMNSS
MAV_4827|M.avium_104                -------------------GGLGGGGGHAP---------------APGGG
MLBr_01556|M.leprae_Br4923          --------YYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSK
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GGAGAEGGAGGG-GGAGGSG-------AGGAGGAG---------------
Mvan_1264|M.vanbaalenii_PYR-1       GGDGSEGGAGGS-GGAGGSG-------TGGAGGAG---------------
Rv3512|M.tuberculosis_H37Rv         GGAGGAGTTGGK-GGTGGNGSGTGSGGTGGDGGTG---------------
Mb3541|M.bovis_AF2122/97            GGAGGAGTTGGK-GGTGGNGSGTGSGGTGGDGGTG---------------
MMAR_1594|M.marinum_M               GGQGGTGGTGGA-AGQGGTGSTMGSDGSSGDGGTGGLGGDGGGAGQGTTG
MUL_4367|M.ulcerans_Agy99           GGDGGGGGSASG-SGTGGSGGTGGVGGIGGDGKLG---------------
MSMEG_0868|M.smegmatis_MC2_155      GGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADG---------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      INASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQG---------------
MAV_4827|M.avium_104                LGGFGGGHSGGGLGGLGGGHK-----------------------------
MLBr_01556|M.leprae_Br4923          VGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLR-----------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ---------------------------------GSGGSGGSGGSGG----
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------------------GSGGSGGSGGAGG----
Rv3512|M.tuberculosis_H37Rv         ---------------------------------GGGGNGGTGWNGGKGDT
Mb3541|M.bovis_AF2122/97            ---------------------------------GGGGNGGTGWNGGKGDT
MMAR_1594|M.marinum_M               TAGAGTGGQGASGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGTGGT
MUL_4367|M.ulcerans_Agy99           ---------------------------------GFGGDGGDGGDGGFGVI
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------EHNTGGNGGNGGDGSEPGP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------HASETAHTTLPGAEHH-
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ---------------------------------REKDDVTEVREGFECGM
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ------------------------SGGAAGDSDD----------------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------SGGAAGDSD-----------------
Rv3512|M.tuberculosis_H37Rv         G-----------------------SGGGAGDGGK----------------
Mb3541|M.bovis_AF2122/97            G-----------------------SGGGAGDGGK----------------
MMAR_1594|M.marinum_M               GGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTGSTMGAEGSSGDGGTG
MUL_4367|M.ulcerans_Agy99           GG----------------------QGGGGGFGGLG---------------
MSMEG_0868|M.smegmatis_MC2_155      GGNG--------------------AGGAGGNGGTG---------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          TLG--------------------YSDIKEGDVIESYELVEKQRA------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         ---------------------APAGGTGGAGGDG--------------GA
Mb3541|M.bovis_AF2122/97            ---------------------APAGGTGGAGGDG--------------GA
MMAR_1594|M.marinum_M               GLGGHGGAGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGTQGA
MUL_4367|M.ulcerans_Agy99           -----------------------GTGAGGAPSDK--------------GI
MSMEG_0868|M.smegmatis_MC2_155      ------------------GTTAGGSGNGGNGGNG--------------GN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         GGKGGSGGV-----------------------------------------
Mb3541|M.bovis_AF2122/97            GGKGGSGGV-----------------------------------------
MMAR_1594|M.marinum_M               GGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTG
MUL_4367|M.ulcerans_Agy99           NGEPGNPG------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGADGTPGTAGTTGANNP--------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1594|M.marinum_M               STMGSAGTAGDGGTGGLGGGGGTGADNTTTVSAGAQGATGGTGGAGGQGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1594|M.marinum_M               TGGAAGTGTGGIQGAGGQGGTGGTGGTGGIGGTGTDSTDPTLAGQAGGQG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------
Rv3512|M.tuberculosis_H37Rv         ----------------
Mb3541|M.bovis_AF2122/97            ----------------
MMAR_1594|M.marinum_M               GTGETGGAAGSGGTGS
MUL_4367|M.ulcerans_Agy99           ----------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------
TH_3810|M.thermoresistible__bu      ----------------
MAB_4284c|M.abscessus_ATCC_199      ----------------
MAV_4827|M.avium_104                ----------------
MLBr_01556|M.leprae_Br4923          ----------------