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PQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGGNGGN GGTGGKGGTGGDGALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDGGKGGNGGIGAAGTTGPVGTG ASGGTGGSGGAGGTGGDGGAANGGTAGAGGAGGNGGKGGDGGAGVTSSTAGNSGGAGGSGGKGGDAGAGG AGATPGANGIAGNGGDGGDGAAGAVGISGATGAGDGGHGGTGAAGGNGGTGGAGGSGIDGVGGGTGGTGG NGGNGAIGGAGGDAGGSGNSGGNGGIGGKGGNAGAGGAAGSNGGTVGANGTGGDGGNGGAAGAATAGSNG GAGTGSAGGNGGTGGRGGSGGAGGDGIGGVGGGKGGNGADGEVGGAGGAGGSGPNTSPGGNGGQGGQGGS GGAGGAAGAGGAGGGANGTAGNGGQGGAGGTGGAGAASSATNGGSGGAGGTGGDGGSGGAGGTGGAGGTG GAAGDGGQGGQGGAGGGAGGQGGAGGAGGTGGNGGNITGGTAGTAGAAGNGGAAGKGGAGGQGGTGGGTG GQGGAGGDGGAGGTGGDRTVGGGTVPAGSGGQGGNAGGGGAGGQGGADGGSGGDGGDAGTGGNGGNGGNR NSGNGTGGAGGNGGGGANGGAGGAGGSGGGTGGNGGAGGDAGDAGNGGNGNGTGNGGNGGNGGIAGMGGN GGAGTGSGNGGNGGSGGNGGNAGMGGNSGTGSGDGGAGGNGGAAGTGGTGGDGGLTGTGGTGGSGGTGGD GGNGGNGADNTANMTAQAGGDGGNGGDGGFGGGAGAGGGGLTAGANGTGGQGGAGGDGGNGAIGGHGPLT DDPGGNGGTGGNGGTGGTGGAGIGSLGGGTGGDGGNGGNGGTGGEGGEVGGAGGTGGAAGNGGDGGTGGT GGGDGGAGGTGGTGGTGGLGDPRVGGSGGDGGTGGSGGAAGNGGNGGNAGAGGNGNGGTGGAGGIGGTGG NGGDAEPGVPPGAGGAGGAGTTGGKGGTGGNGSGTGSGGTGGDGGTGGGGGNGGTGWNGGKGDTGSGGGA GDGGKAPAGGTGGAGGDGGAGGKGGSGGV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3512 | PE_PGRS56 | - | 100% (1079) | PE-PGRS FAMILY PROTEIN |
M. tuberculosis H37Rv | Rv3514 | PE_PGRS57 | 0.0 | 52.60% (1194) | PE-PGRS family protein |
M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 0.0 | 51.16% (1245) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3541 | PE_PGRS55 | 0.0 | 95.97% (1117) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 0.0 | 49.34% (835) | triple helix repeat-containing collagen |
M. leprae Br4923 | MLBr_01556 | infB | 1e-10 | 35.83% (120) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_4284c | - | 2e-62 | 32.80% (561) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_1594 | - | 0.0 | 53.15% (1240) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 2e-27 | 42.93% (184) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 0.0 | 41.61% (1091) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 5e-51 | 44.67% (291) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 51.03% (1017) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 0.0 | 48.10% (842) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADEVSAR MMAR_1594|M.marinum_M MSYMSISPEIVSSAAGELANIGSTVSAANAAAAVATTELLAAGSDEVSTR MUL_4367|M.ulcerans_Agy99 MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDEVSAA MSMEG_0868|M.smegmatis_MC2_155 -----MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 IAALFGMYGLEYQAISAQVAAYHQQFVQTLRTGAASYMLAEAT------N MMAR_1594|M.marinum_M IAALFGANGVEYQAISAQIASFHDRFVAALNTGTSSYVWAEAT------N MUL_4367|M.ulcerans_Agy99 IAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQE MSMEG_0868|M.smegmatis_MC2_155 LAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 VEQNLLNLINAPTQTLLGRPLIGDGANATTPGGAGGDGGLLFGSGGNGAP MMAR_1594|M.marinum_M VEQNLLNAVNAPVQTLLGRPLIGNGANATTPGGAGGDGGLLYGSGGNGAA MUL_4367|M.ulcerans_Agy99 LEQQALGVVNAPSMALFGRPSIGN-------------------------- MSMEG_0868|M.smegmatis_MC2_155 TDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GAPGQAGGAGGSAGLLGNGGSGGAGGTG-APGGNGGNAGWLYGRGGVGGA MMAR_1594|M.marinum_M GAPGQAGGAGGSAGLWGNGGSGGSGGIGGGTGGNGGSGGWLLGRGGIGGA MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 LIPNAPTEPADMPGVWAVMAWAR--------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGIGGGTGGAGGHAWLFGHGGTG--------------------------- MMAR_1594|M.marinum_M GGTGGGSGGSGGGAWLFGDGGAGGMGGTGGSGGGFGGTGGHGGLLYGNGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1594|M.marinum_M AGGAGATGQTGGSGGWAALWGRGGAGGAGGDNGGFAGGDGGHGGLLCGAG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ---GIGGGPGGNGGWLLGNGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGG MMAR_1594|M.marinum_M GDGGLGGGDGGNAGWLLGFGGHGGAGGDGGFAGGEGGNGGWLLGFGGHGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 AGGTGGGAGGTGGNAAWLLGGGGTGGAGGIGGGNGGHGGNGGWLLGNGGN MMAR_1594|M.marinum_M TGGIGGGTGGAGGAGGLVMGFGGHGGTGGIGGGAGGAGGQAALLFGHGGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGAGSTGTAGGGSGGT MMAR_1594|M.marinum_M GGAGGVGTAGGAGGAGGDGGNPGWLLGRAGSGGDGGAGGAATTVGATGGV MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGDGGTGGRGGLLMGAGAGGHGGTGGAGGAGVDGGGAGG------AGGAG MMAR_1594|M.marinum_M GGHGGAGGRGGVLMGGGAGGDGGAGGAGADGSNGVGDGGNGATGGGGGVG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GNGGAGGQAALLFGRGGTGGAGGYGGDGGGGGDGFDGTMAGLGGTGGSGG MMAR_1594|M.marinum_M GDGGAGGQAALLFGCGGTGGHAGAGGAGGGGGTGADS----LTGIGGAGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 TGGDGGAPGNGGAGGAGQLLSHSGVAGASGKGGAGGTGGNGGAGSAGADA MMAR_1594|M.marinum_M DGGIGGASGQAGAGGAGNLFSHNGSRGHAGIGGDGGDGGTGGTGGEGTDA MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 PAGSGAMGSTGFAGGAGGDGGNGGGSGA---------------------- MMAR_1594|M.marinum_M AAGSGLTGGTGYAGGTGGTGGAGGNSGLGGTNGSGGHGGTGGTGGTGGTG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1594|M.marinum_M GSGADNTTGIGGDGGQGGTGGDAGAGGAGGNSGFGGTGGTTGTHGDAGIG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ------------------------------------------------SQ MMAR_1594|M.marinum_M GDGGDGGTGGTGGQGTDAAAGTGLTGGTGYAGGTGGAGGAGGNSGLGGTN MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GNGGNGGNGGTGGKGGTGGAGMNSLDP----------------------- MMAR_1594|M.marinum_M GSGGHGGTGGTGGTGGTGGSGADALDGSGASGHDGGDSGAGGDGGTGGAG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1594|M.marinum_M GNAGTGAGAAGNNGDGGAGGTGGNSGAQAGDGGAGAANTTIGGTGGAGGS MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1594|M.marinum_M GGNIGAGGAGGQGGAAGTTSGVGGASGTSGTSGQSIGTGGDGGAGGDGGT MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1594|M.marinum_M GTTGADAAAGSGLGGDIGGTGGAGGAGGTGGSGGTDSGVGGSGGVGGVGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ---------------LLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAG MMAR_1594|M.marinum_M TGGQGGAGSDNSANAGVAGGAGGQGGAGGTGGAAGSGGTGSVAGADGSSG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 NGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTG MMAR_1594|M.marinum_M DGGTGGLGGDGGAGGTGSMGAVDGGTGGQGASGGAGGQGGTGGAAGAGTG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAG MMAR_1594|M.marinum_M GIQGAGGQGGTGGTGGTGGTGGDGAESTDPSLAGQAGGQGGTGGTGGAAG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 AGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGA MMAR_1594|M.marinum_M QGGTGSVTGAEGSAGDGGTGGLGGDGGTGADNTTTVSAGAQGATGGTGGA MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQ MMAR_1594|M.marinum_M GGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGDGAESTDPTLAAQ MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ---------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP Rv3512|M.tuberculosis_H37Rv ---------------------PQGADGNAGNGGDGGVGGNGGNGADNTTT Mb3541|M.bovis_AF2122/97 DGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTT MMAR_1594|M.marinum_M AGGQGGTGGTGGAAGQGGTGSTMGAEGSSGDGGTGGLGGDGGAGADNTTT MUL_4367|M.ulcerans_Agy99 -----------------------GVDGVAGTGQAGGAGGILWGNGGNGGL MSMEG_0868|M.smegmatis_MC2_155 ------RQPMYSDPAMRTTVNPQAQLPVPTVASAVLDPTQIVNWLIYQPL TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------MSIIDFILNLFRDPVEAASYVADPEAAL MAV_4827|M.avium_104 -------------------------------MNIVLGVSMAPSSIQMVVL MLBr_01556|M.leprae_Br4923 ----------------------MAGKARVHELAKELGVTSKEVLARLNEQ Mflv_5091|M.gilvum_PYR-GCK --MVTFGGGATPTPTSLGAAAVDLSGT---SCGLICNGQDGTGQNGGILF Mvan_1264|M.vanbaalenii_PYR-1 WYVVSFGGSGAPTPNNLAASLVDLSGT---SCGLICNGQDGTGQNGGILF Rv3512|M.tuberculosis_H37Rv AAAGTTGGAGGAGGAGGTGGTGGAAGTG--TGGQQGNGGNGGNGGTGGKG Mb3541|M.bovis_AF2122/97 AAAGTTGGAGGAGGAGGTGGTGGAAGTG--TGGQQGNGGNGGNGGTGGKG MMAR_1594|M.marinum_M VSTGAQGATGGTGGAGGQGGTGGAAGTG--TGGIQGAGGQGGTGGTGGTG MUL_4367|M.ulcerans_Agy99 GAAGANGGAGGSAGLIGTGGVGGAGGVG--AAGMTGGSGGAG-GGGGWLW MSMEG_0868|M.smegmatis_MC2_155 HAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTADNPNGGTGGLLF TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQN MAV_4827|M.avium_104 EGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQL MLBr_01556|M.leprae_Br4923 GEFVKSASSTVEAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESL Mflv_5091|M.gilvum_PYR-GCK GNGGSG----------WNSDVVGMDGGNGGNGGLFG--------GNGGNG Mvan_1264|M.vanbaalenii_PYR-1 GNGGSG----------WNSEIAGVSGGNGGNAGLFG--------GNGGNG Rv3512|M.tuberculosis_H37Rv GTGGDG-------ALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDG Mb3541|M.bovis_AF2122/97 GTGGDG-------ALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDG MMAR_1594|M.marinum_M GSGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDG MUL_4367|M.ulcerans_Agy99 GAGGSG-----------GAAGAGGSGGSGG--WLWGNAGQTAGAGVGGAG MSMEG_0868|M.smegmatis_MC2_155 GDGGHG----------YDGSAAGLAGGNGGNAGLFG---------NGGNG TH_3810|M.thermoresistible__bu ---------------------VDGDGGSGGRTGLFS------KLSRGGDG MAB_4284c|M.abscessus_ATCC_199 YYAAQP----------DGPSILSPSLLSPRDNDFLSHNDTDFASHNPIAS MAV_4827|M.avium_104 SSIGVT----------WTDQLEAAALRDALAARRIDNVMLVSAFLAAAAL MLBr_01556|M.leprae_Br4923 DQTLDR----------ALDKAVAGNGATTAAPVQVDHSAAVVPIVAGEGP . Mflv_5091|M.gilvum_PYR-GCK GNGLGGGNGGNG------------GNAGAFALFG-NGGNGGNGGVGVVG- Mvan_1264|M.vanbaalenii_PYR-1 GNGLGSGDGGNG------------GDAGLFSLFG-RGGNGGNGGVGIAG- Rv3512|M.tuberculosis_H37Rv GKGGNGGIGAAGTTG-----PVGTGASGGTGGSGGAGGTGGDGGAANGG- Mb3541|M.bovis_AF2122/97 GKGGNGGIGAAGTTG-----PVGTGASGGTGGSGGAGGTGGDGGAANGG- MMAR_1594|M.marinum_M GTGGLGGDGGEGGQGTTAWNPGDTGGQGASGGAGGTGGTGGAAGTGTGG- MUL_4367|M.ulcerans_Agy99 GAGGAGDAGDQGVSG------VAPGEAGAVGFAGGAGGAGGAGGNGVGGG MSMEG_0868|M.smegmatis_MC2_155 GVGWAGLDGGNG---------------GSGGLLMGIGGAGGAGGVGADG- TH_3810|M.thermoresistible__bu GDGGLGGNGGHG------------------------GGTGIISLLSLAG- MAB_4284c|M.abscessus_ATCC_199 GNQVMSPSGNVDSFN----------RGPLLDLSFGDLQFGNRDTTAIG-- MAV_4827|M.avium_104 AQNVGGAMGYER---------------TAVLLVEPDTATLAVVETSDGSI MLBr_01556|M.leprae_Br4923 STAHREELAPPAGQP----------SEQPGVPLPGQQGTPAAPHPGHPGM . . . Mflv_5091|M.gilvum_PYR-GCK --ATGAVGAPGVAGATGATG-------VTSGVVGGNGEDAVGYGATGAAG Mvan_1264|M.vanbaalenii_PYR-1 --ATGAVGAPGVAGATGATG-------VTSNVTGGNGADAVGYGATGAAG Rv3512|M.tuberculosis_H37Rv TAGAGGAGGNGGKGGDGGAG-------VTSSTAGNSGGAGGSGGKGGDAG Mb3541|M.bovis_AF2122/97 TAGAGGAGGNGGKGGDGGAG-------VTSSTAGNSGGAGGSGGKGGDAG MMAR_1594|M.marinum_M IQGAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAG MUL_4367|M.ulcerans_Agy99 VNGAGGAGGAGGVGGGGGAGASG----VGAGVAGGDGGTGGAGGAAGVGG MSMEG_0868|M.smegmatis_MC2_155 ----TSAHVDGGTGGTGGTG----------GGTGGTGGIGGTGG--GLFG TH_3810|M.thermoresistible__bu ---------NGGNGGNG--------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---DGAVAVGGSNSGPIASG---------------QGSTAVNGDVRDSNI MAV_4827|M.avium_104 PDVYKQQIRAESYGDAAG---------------------------QLSAM MLBr_01556|M.leprae_Br4923 PTGPHPGPAPKPGGRPPRVG-----------NNPFSSAQSVARPIPRPPA . Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGAAGAVGSAGAA-----GEAGETGTWG-NAGLP-GKAGDAGG Mvan_1264|M.vanbaalenii_PYR-1 AAGAAGAAGKAGAVGSAGTA-----GSAGAPGVWG-NAGLP-GAAGAAGG Rv3512|M.tuberculosis_H37Rv AGGAGATPGANGIAGNGGDG---GDGAAGAVGISG-ATGAGDGGHGGTGA Mb3541|M.bovis_AF2122/97 AGGAGATPGANGIAGNGGDG---GDGAAGAVGISG-ATGAGDGGHGGTGG MMAR_1594|M.marinum_M TGGTGSTMGAEGSSGDGGSGGLGGDGGAGGQGTTG-TAGAGTGGQGASGG MUL_4367|M.ulcerans_Agy99 AAGTGGTGGAAGVAGTGGDG---GDGGAGGAGSDA-SLAGQAGFAGGSGG MSMEG_0868|M.smegmatis_MC2_155 LLGHSGSTGAAGAAGNGGDG---GNGGFGYVLIAGPNVTVGSETRGGTGG TH_3810|M.thermoresistible__bu ---YRTTDNNALDGGHGGNG-----GNVGFFSLFN------------LGG MAB_4284c|M.abscessus_ATCC_199 INADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTN MAV_4827|M.avium_104 VAGLEKLESLPGGLLLVGSG----VDVAPLKQVLQTTTFLDVSVAEEPET MLBr_01556|M.leprae_Br4923 PRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGG . Mflv_5091|M.gilvum_PYR-GCK AGAVGAAGAAGTVG--------------------TAGATGGT-------- Mvan_1264|M.vanbaalenii_PYR-1 AGAIGTAGVAGAAG--------------------TAGATGGT-------- Rv3512|M.tuberculosis_H37Rv AGGNGGTGGAGGSGIDGVG--GGTGGTGGNGGNGAIGGAGGD-------- Mb3541|M.bovis_AF2122/97 AGGNGGTGGAGGSGIDGVG--GGTGGTGGNGGNGAIGGAGGD-------- MMAR_1594|M.marinum_M AGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQIA MUL_4367|M.ulcerans_Agy99 AGGVGGSAGAGG-----------------------VNGSGGD-------- MSMEG_0868|M.smegmatis_MC2_155 AGGTGGQSTAAGPGKGGGG-------GGGGGGAILIGANGGTVDG----- TH_3810|M.thermoresistible__bu AGGWGGSGVDG------------------------VDVVGGN-------- MAB_4284c|M.abscessus_ATCC_199 INDSFNTDRSTNIG------------------------SGNT-------- MAV_4827|M.avium_104 ALARGAALAAANAP--------------------LFASSTAALAY----- MLBr_01556|M.leprae_Br4923 GNYRGGGVGALPGG----------------GSGGFRGRPGGG-------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -AGGSGNSGGNG-------------------------------------- Mb3541|M.bovis_AF2122/97 -AGGSGNSGGNG-------------------------------------- MMAR_1594|M.marinum_M QAGGQGGTGGTGGAAGQGGTGSTIGSAGTAGDGGTGGLGGDGGTGADNTT MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------GTGANGGAG-----------------------GVGG Mvan_1264|M.vanbaalenii_PYR-1 --------------GVGGNGGAG-----------------------QAGG Rv3512|M.tuberculosis_H37Rv -----------GIGGKGGNAGAGGAAGS-------------NGGTVGANG Mb3541|M.bovis_AF2122/97 -----------GTGGKGGNAGAGGAAGS-------------NGGTVGANG MMAR_1594|M.marinum_M TVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGG MUL_4367|M.ulcerans_Agy99 -------------GGAGAAGGAGGASAT----------------VAGSGG MSMEG_0868|M.smegmatis_MC2_155 ----------HAIGGNGGNGGNGSTTAAG-----------------GNGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK VGGT--------------------GAAGAAG------------------- Mvan_1264|M.vanbaalenii_PYR-1 IGGT--------------------GAAGAAG------------------- Rv3512|M.tuberculosis_H37Rv TGGD-------------------GGNGGAAG-------AATAGSNGGAGT Mb3541|M.bovis_AF2122/97 TGGD-------------------GGNGGAAG-------AATAGSNGGAGT MMAR_1594|M.marinum_M TGGDGADSTDPTLAGQAGGQGGTGGTGGAAGQGGTGSTSGSEGSSGDGGT MUL_4367|M.ulcerans_Agy99 VGGD-------------------GGAGGAAG--------------GGVG- MSMEG_0868|M.smegmatis_MC2_155 TGGTG--------------RVIAEGTGSTAEG-------TATGGDGGHST TH_3810|M.thermoresistible__bu ------------------------PDGGTPG------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------TNTEIG------------------- MAV_4827|M.avium_104 ------------------------AQDPGTG------------------- MLBr_01556|M.leprae_Br4923 ------------------------GHGGGGR------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------G Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------Q Rv3512|M.tuberculosis_H37Rv G------------------------------------------------S Mb3541|M.bovis_AF2122/97 G------------------------------------------------S MMAR_1594|M.marinum_M GGLGGDGGAGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGTQG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 G-----------------------------------------------TG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK AGGLGETG---TTGGAGGVGGQ---------------------------- Mvan_1264|M.vanbaalenii_PYR-1 AGTAGETG---VTGGVGGIGGQ---------------------------- Rv3512|M.tuberculosis_H37Rv AGGNGGTG---GRGGSGGAGGD---------------------------- Mb3541|M.bovis_AF2122/97 AGGNGGTG---GRGGSGGAGGD---------------------------- MMAR_1594|M.marinum_M AGGQGGTG---GTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAG MUL_4367|M.ulcerans_Agy99 AASLGGDG---GHAGAGGAGGE---------------------------- MSMEG_0868|M.smegmatis_MC2_155 IGGNGGIGSVYAYGNNGAVSGTATG------------------------- TH_3810|M.thermoresistible__bu AHGESHTP---------GVYTD---------------------------- MAB_4284c|M.abscessus_ATCC_199 SHNQANIG------------------------------------------ MAV_4827|M.avium_104 AVDQYSLPDYLYVPVDPEPGDD---------------------------- MLBr_01556|M.leprae_Br4923 PGQRGGAAGAFGRPGGAPRRGR---------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------GTAGGT Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------GTEGGT Rv3512|M.tuberculosis_H37Rv -----------------GIGGVGG---------------GKGGNGADGEV Mb3541|M.bovis_AF2122/97 -----------------GIGGVGG---------------GKGGNGADGEV MMAR_1594|M.marinum_M QGGTGSTMGSDGSSGDGGTGGLGGDGGEGGQGTTGTAGAGTGGQGASGGA MUL_4367|M.ulcerans_Agy99 ---------------------------------------GLSGGFNTGAA MSMEG_0868|M.smegmatis_MC2_155 ---------------------------------------GRGGDGIDGGT TH_3810|M.thermoresistible__bu ----------------------------------------------RQGE MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------TSTSA MAV_4827|M.avium_104 -------------------------------------------ELAYSAV MLBr_01556|M.leprae_Br4923 -------------------------------------------KSKRQKR Mflv_5091|M.gilvum_PYR-GCK GGVGGIG------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GGVGGVG------------------------------------------- Rv3512|M.tuberculosis_H37Rv GGAGGAG-----------GSGPNTSPGGNGGQG----------------- Mb3541|M.bovis_AF2122/97 GGAGGAG-----------GSGPNTSPGGNGGQG----------------- MMAR_1594|M.marinum_M GGTGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGDGADSTDPTLAGQ MUL_4367|M.ulcerans_Agy99 GGIGGAG------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGAGGMG------------------------------------------- TH_3810|M.thermoresistible__bu DGEDGTG------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGSAAVG------------------------------------------- MAV_4827|M.avium_104 GEEDAES------------------------------------------- MLBr_01556|M.leprae_Br4923 QEYDSMQAP----------------------------------------- . Mflv_5091|M.gilvum_PYR-GCK -----GAGSTG------------AVGGVGGKGIQGGQ-GLQGGKG----- Mvan_1264|M.vanbaalenii_PYR-1 -----GVGATG------------GAGGVGGKGIQGGQ-GLQGGQG----- Rv3512|M.tuberculosis_H37Rv --GQGGSGGAGGAAGAGGAG--GGANGTAGNGGQGGA-GGTGGAGAASSA Mb3541|M.bovis_AF2122/97 --GQGGSGGAGGAAGAGGAG--GGANGTAGNGGQGGA-GGTGGAGAASSA MMAR_1594|M.marinum_M AGGQGGTGGTGGAAGQGGTGSVAGTDGSSGDGGTGGL-GGHGGAGADNTT MUL_4367|M.ulcerans_Agy99 -----GAGGTGGDSG--------GVGGVNGDGGAGGG-GGRGGDGGSSTS MSMEG_0868|M.smegmatis_MC2_155 ---EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGG TH_3810|M.thermoresistible__bu -------------------------TGIGGRGGNGGS------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------GNAGLAGNAGLAGN------------- MAV_4827|M.avium_104 -----------------------PTVVIEKLFLPEDS------------- MLBr_01556|M.leprae_Br4923 -----------------------VVGGVRLPHGNGETIRLARGASLSDFA Mflv_5091|M.gilvum_PYR-GCK -----------GDGGAGGKGGDA----------------------DSMG- Mvan_1264|M.vanbaalenii_PYR-1 -----------GDGGTGGTGGDA----------------------TSMG- Rv3512|M.tuberculosis_H37Rv TN--------GGSGGAGGTGGDG--------------------GSGGAGG Mb3541|M.bovis_AF2122/97 TN--------GGSGGAGGTGGAG--------------------GTGGAGG MMAR_1594|M.marinum_M TVSAGAQGATGGTGGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGG MUL_4367|M.ulcerans_Agy99 TS---------GVGGAGGAGGNG--------------------GNAGFG- MSMEG_0868|M.smegmatis_MC2_155 KASG------TAKAGHGGKASDG--------------------GKGGNGG TH_3810|M.thermoresistible__bu ------------SSGTHPMAEDG--------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------AGLAGNAGLAG--------------------------- MAV_4827|M.avium_104 ----------EPRRRPVLLVGSG--------------------------- MLBr_01556|M.leprae_Br4923 EKIDAN-----PAALVQALFNLG--------------------------- . Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------------SAGA Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------------EAGA Rv3512|M.tuberculosis_H37Rv TGG--------------------------------------------AGG Mb3541|M.bovis_AF2122/97 DGVGGAG-----------GGNGGHGGDAGDGGNGANGNNRSSGSFLAAGG MMAR_1594|M.marinum_M TGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGQGGTGSTSGSAGSSGDGG MUL_4367|M.ulcerans_Agy99 ---------------------------------------------VSAGG MSMEG_0868|M.smegmatis_MC2_155 D-----------------------------------------ALVMAAGA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------------------------LAVVGI MLBr_01556|M.leprae_Br4923 ---------------------------------------------EMVTA Mflv_5091|M.gilvum_PYR-GCK TGGKGGNGGNGGR----------------GGLFG---------------- Mvan_1264|M.vanbaalenii_PYR-1 TGGKGGNGGNGGR----------------GSLFG---------------- Rv3512|M.tuberculosis_H37Rv TGGAAGDGGQGGQ----------------GGAGG---------------- Mb3541|M.bovis_AF2122/97 TGGAAGDGGQGGQ----------------GGAGG---------------- MMAR_1594|M.marinum_M TGGLGGDGGEGGQGTTGTAGAGTGGQGASGGAGGQGGTGGAAGTGTGGTQ MUL_4367|M.ulcerans_Agy99 TGGSAGDGGAGGG---------------AGGVDGVG-------------- MSMEG_0868|M.smegmatis_MC2_155 TGVATGNTAIGGN----------------GGAAS---------------- TH_3810|M.thermoresistible__bu EHVKALDGRPGLD------------------------------------- MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGN------------------------------------- MAV_4827|M.avium_104 SAVLALEIALAIG------------------------------------- MLBr_01556|M.leprae_Br4923 TQSVGDETLELLG------------------------------------- : Mflv_5091|M.gilvum_PYR-GCK -KGGNAGNGADGGTGGAGGA------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 -RGGNAGNGGNGGTGGNGGN------------------------------ Rv3512|M.tuberculosis_H37Rv GAGGQGGAGGAGGTGGNGGN------------------------------ Mb3541|M.bovis_AF2122/97 GAGGQGGAGGAGGTGGNGGN------------------------------ MMAR_1594|M.marinum_M GAGGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGG MUL_4367|M.ulcerans_Agy99 GASGNGGAAGAGGAGGSGIG------------------------------ MSMEG_0868|M.smegmatis_MC2_155 ANGAVGGNGGFTNIAAIHGS------------------------------ TH_3810|M.thermoresistible__bu --GGNGSHGGNGGHGGR--------------------------------- MAB_4284c|M.abscessus_ATCC_199 --AGLAGNAGLAGNAGLAGN------------------------------ MAV_4827|M.avium_104 --IRTTGTVALQPTPNQHLIVP---------------------------- MLBr_01556|M.leprae_Br4923 --SEMNYNVQVVSPEDEDRELLEP-------------------------- Mflv_5091|M.gilvum_PYR-GCK -----------------------------------------GGTGGTGGA Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------------GGTGGTGGN Rv3512|M.tuberculosis_H37Rv ---------------------------------------ITGGTAGTAGA Mb3541|M.bovis_AF2122/97 ---------------------------------------ITGGTAGTAGA MMAR_1594|M.marinum_M TGSTMGSAGTAGDGGTGGLGGHGGTGADNTTTVSAGAQGATGGTGGAGGQ MUL_4367|M.ulcerans_Agy99 ----------------------------------------AGIDGGAGGA MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------ITDSSATSGHGGA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK G--GTGGTGGTG-----GIGGAGSTG--------GTG------------- Mvan_1264|M.vanbaalenii_PYR-1 G--GTGGTGGTG-----GIGGAGSTG--------GTG------------- Rv3512|M.tuberculosis_H37Rv A--GNGGAAGKG-----GAGGQGGTG-------GGTG------------- Mb3541|M.bovis_AF2122/97 A--GNGGAAGKG-----GAGGQGGTG-------GGTG------------- MMAR_1594|M.marinum_M G--GTGGAAGTGTGGTQGAGGQGGTGGTGG--QGGTGGTGTDSTDPTLVG MUL_4367|M.ulcerans_Agy99 G--GTGGAAGFP-------GGGGTTG------AWGTG------------- MSMEG_0868|M.smegmatis_MC2_155 AQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNG------------- TH_3810|M.thermoresistible__bu ------------------------------------G------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---GTGGTGGTGGT-GGTGG------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGTGGTGGT-GGTGG------------------------------ Rv3512|M.tuberculosis_H37Rv ---GQGGAGGDGGA-GGTGGDRTVGGGTVPAGSGG--------------- Mb3541|M.bovis_AF2122/97 ---GQGGAGGDGGA-GGTGGDRTVGGGTVPAGSGG--------------- MMAR_1594|M.marinum_M QAGGQGGTGGTGGA-AGQGGTGSVTGAEGSAGDGGSGGLGGHGGTGADNT MUL_4367|M.ulcerans_Agy99 ---GAGGAGGAGGA-GDHGGVGVNPGDSGTAGWAG--------------- MSMEG_0868|M.smegmatis_MC2_155 ---GDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG------------- TH_3810|M.thermoresistible__bu ---GFLGIGGS--------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --AGLAGNAGLAGN------------------------------------ MAV_4827|M.avium_104 ---TEQAPAPPP-------------------------------------- MLBr_01556|M.leprae_Br4923 FDLTYGEDQGDEDELQVRPPVVT--------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------TGGTGGTGG-----------------------TGGKGGTG Mvan_1264|M.vanbaalenii_PYR-1 ----------TGGTGGTGG-----------------------TGGKGGTG Rv3512|M.tuberculosis_H37Rv -------QGGNAGGGGAGGQGGAD----------------GGSGGDGGDA Mb3541|M.bovis_AF2122/97 -------QGGNAGGGGAGGQGGAD----------------GGSGGDGGDA MMAR_1594|M.marinum_M TAVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQG MUL_4367|M.ulcerans_Agy99 ---------GAGGAGGAGGSAAFN-----------------GVNGAGGAG MSMEG_0868|M.smegmatis_MC2_155 -------QTDTGGNGGRGGDGGTFVN--------------AGANGNGGAG TH_3810|M.thermoresistible__bu -------------------------------------------GGWGGHG MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------AGLAGNA MAV_4827|M.avium_104 ------------------------------------------VQASAPQP MLBr_01556|M.leprae_Br4923 ------------------------------------------VMGHVDHG . Mflv_5091|M.gilvum_PYR-GCK GTGGA-------------------GGTGGDGGTG---------------G Mvan_1264|M.vanbaalenii_PYR-1 GTGGD-------------------GGTGGTGGTG---------------G Rv3512|M.tuberculosis_H37Rv GTGGN-------------------GGNGGNRNSG--------------NG Mb3541|M.bovis_AF2122/97 GTGGN-------------------GGNGGNRNSG--------------NG MMAR_1594|M.marinum_M GTGGTGTDSTDPTLAGQAGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDGG MUL_4367|M.ulcerans_Agy99 GNGGA-------------------GGGGGAGASG--------------IG MSMEG_0868|M.smegmatis_MC2_155 GAGGVS------------------EGEGGTGGHG---------------G TH_3810|M.thermoresistible__bu GNGGD--------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGN--------------------------------------------- MAV_4827|M.avium_104 KISVP--------------------------------------------- MLBr_01556|M.leprae_Br4923 KTRLLDTIR---------------------------------------KA Mflv_5091|M.gilvum_PYR-GCK TGGTGGTG-------------------GTGGTGGTGGAG----------- Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTG-------------------GTGGTGGTGGAG----------- Rv3512|M.tuberculosis_H37Rv TGGAGGNG----------------GGGANGGAGGAGGSG----------- Mb3541|M.bovis_AF2122/97 TGGAGGNG----------------GGGANGGAGGAGGSG----------- MMAR_1594|M.marinum_M TGGLGGDGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAAGTGTGGTQ MUL_4367|M.ulcerans_Agy99 AGVAGGDG-------------------GTGGTGGAAGTG----------- MSMEG_0868|M.smegmatis_MC2_155 DGGRGGDG-------------------ALGGNGGTGGVG----------- TH_3810|M.thermoresistible__bu TDADGGNG-------------------GDGGNGGSAGRG----------- MAB_4284c|M.abscessus_ATCC_199 AGLAGNAG-------------------LAGNAGLAGNAG----------- MAV_4827|M.avium_104 EPVAAPKP-------------------LSPPVAAPLPAAP---------- MLBr_01556|M.leprae_Br4923 NVREAEAG-------------------GITQHIGAYQVG----------- . . . Mflv_5091|M.gilvum_PYR-GCK ----------------------------------DGTGGTGGTGGTGGQG Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------DGLGGTGGTGGTGGFG Rv3512|M.tuberculosis_H37Rv -------------------------------GGTGGNGGAGGDAGDAGNG Mb3541|M.bovis_AF2122/97 -------------------------------GGTGGNGGAGGDAGDAGNG MMAR_1594|M.marinum_M GAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGSG MUL_4367|M.ulcerans_Agy99 --------------------------------GAAGTGGTGGAAGAAGSA MSMEG_0868|M.smegmatis_MC2_155 -------------------------------LGNGGKGGNGGNGGNGGTY TH_3810|M.thermoresistible__bu --------------------------------------GTGGLRGVFGIN MAB_4284c|M.abscessus_ATCC_199 ---------------------------------LAGNAGLAGNAGLAGNA MAV_4827|M.avium_104 ---------------------------------PPAAPPLPEAPPIPAAP MLBr_01556|M.leprae_Br4923 -------------------------------VDLDGSERLITFIDTPGHE . Mflv_5091|M.gilvum_PYR-GCK GQGGQGGTGGTGGQGGLGGGGGTGGQG----------------------- Mvan_1264|M.vanbaalenii_PYR-1 GQGGQGGTGGTGGQGGLGGVGGTGGTG----------------------- Rv3512|M.tuberculosis_H37Rv GNGNGTGNGGNGGNGGIAGMGGNGGAG----------------------- Mb3541|M.bovis_AF2122/97 GNGNGTGNGGNGGNGGIAGMGGNGGAG----------------------- MMAR_1594|M.marinum_M GTGSTMGAEGSSGDGGTGGLGGDGGTGGQGTTAVNPGDTGGQGASGGAGG MUL_4367|M.ulcerans_Agy99 GDGGAGGAGGAGDDGSAGVVSGDPGTAG---------------------- MSMEG_0868|M.smegmatis_MC2_155 VDPSHTGAGGNGGNGGAGRIRVNNGTATG--------------------- TH_3810|M.thermoresistible__bu GGNGRAGLGGRGXXX----------------------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAAVAGNAAVAGNAAVAG---------------------- MAV_4827|M.avium_104 PVVPVPVVVPPVPVPVPVRIPVPDPVS----------------------- MLBr_01556|M.leprae_Br4923 AFTAMRARGAKATDIAILVVAADDGVMP---------------------- Mflv_5091|M.gilvum_PYR-GCK ----------GTGGTGGQGGTG-GTGGTGGTGGTGG-------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------GTGGTGGQGGTG-GTGGTGGTGGTGG-------------- Rv3512|M.tuberculosis_H37Rv -------TGSGNGGNGGSGGNG-GNAGMGGNSGTGS-------------- Mb3541|M.bovis_AF2122/97 -------TGSGNGGNGGSGGNG-GNAGMGGNSGTGS-------------- MMAR_1594|M.marinum_M TGGTGGAAGTGTGGTQGAGGQG-GTGGTGGQGGTGGDGTDNSTTPGAAGG MUL_4367|M.ulcerans_Agy99 ----------KAGGAGGAGGVG-GNGVAGGVNGSGG-------------- MSMEG_0868|M.smegmatis_MC2_155 ---------TATGGNGGNGGNGDADGHRGGKGGDGGE------------A TH_3810|M.thermoresistible__bu ----------XGGGVGAAVRSG--NGVFSGGGGTPSAGFG---------- MAB_4284c|M.abscessus_ATCC_199 -----------NAAVGGVLNTG-VSGAIGGSSHVGG-------------- MAV_4827|M.avium_104 -----------PPQLLAPPRLSVPQPVQPPVRVPQP-------------- MLBr_01556|M.leprae_Br4923 -----QTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRG---------- . Mflv_5091|M.gilvum_PYR-GCK ------AGGDGGLGGLGGFG------------------GSGGTGG----- Mvan_1264|M.vanbaalenii_PYR-1 ------AGGDGGLGGLGGFG------------------GVGGTGG----- Rv3512|M.tuberculosis_H37Rv --GDGGAGGNGGAAGTGGTG------------GDGGLTGTGGTGG----- Mb3541|M.bovis_AF2122/97 --GDGGAGGNGGAAGTGGTG------------GDGGLTGTGGTGG----- MMAR_1594|M.marinum_M AGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDGGTGGLGGAGGTGGQGTTA MUL_4367|M.ulcerans_Agy99 ------AGGAGGAGGTGGAG----------------ASGVPASVD----- MSMEG_0868|M.smegmatis_MC2_155 LIRATVIGSNASGTATGGDG------------------GNGGTLG----- TH_3810|M.thermoresistible__bu ---------------------------------------VPTTIQ----- MAB_4284c|M.abscessus_ATCC_199 -------AINESLGGSGSVG------------------GSTAVGG----- MAV_4827|M.avium_104 -------PSPPQVGGTVPQS-------------------PPQHQT----- MLBr_01556|M.leprae_Br4923 ------QLTEYGLVAEDFGG-------------DTMFIDISAKVG----- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------QGGLGGPGGSTGG Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------QGGQGGPGGSTGG Rv3512|M.tuberculosis_H37Rv ----------------------------------SGGTGGDGGNGGNG-- Mb3541|M.bovis_AF2122/97 ----------------------------------SGGTGGDGGNGGNGGN MMAR_1594|M.marinum_M VNPGDTGGQGASGGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGAGGSGGT MUL_4367|M.ulcerans_Agy99 -----------------------------------GGDGGAGGAGGAAG- MSMEG_0868|M.smegmatis_MC2_155 ------------------------------------ATNGTGGAATIVAY TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 --------------------------------------TNIEALLEAVLL Mflv_5091|M.gilvum_PYR-GCK -------------AGGAGGQAGTAGKGGLFG-----GSGSAGKAGATGAA Mvan_1264|M.vanbaalenii_PYR-1 -------------AGGAGGQAGVAGKGGLFG-----GSGSAGTAGVTGAS Rv3512|M.tuberculosis_H37Rv -ADNTANMTAQ--AGGDGGNGGDGGFGGGAG-----AGGGGLTAGANGTG Mb3541|M.bovis_AF2122/97 GADNTANMTAQ--AGGDGGNGGDGGFGGGAG-----AGGGGLTAGANGTG MMAR_1594|M.marinum_M GGDGTDNSTTPGAAGGAGGQGGTGGTGGAAG-----SGGTGSTMGAEGSS MUL_4367|M.ulcerans_Agy99 -------------TGGSGGSAGNTGAGGAGG-----AGGAGGSAASTGVN MSMEG_0868|M.smegmatis_MC2_155 NVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAG TH_3810|M.thermoresistible__bu ------------FPAGSCTSRAVSREGIMPS-----SRAASARAGAACAS MAB_4284c|M.abscessus_ATCC_199 ----------GAHTGVGGGVSTGVGVGSHVG------GGISESLGGSGSV MAV_4827|M.avium_104 -------------PPGEGTPPKPDGPGNYGG-----GHVPTPGAGGSGGS MLBr_01556|M.leprae_Br4923 TADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVA . Mflv_5091|M.gilvum_PYR-GCK G--ASGGKGAQGATGAQG-------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 G--ASGGKGAQGATGAQG-------------------------------- Rv3512|M.tuberculosis_H37Rv GQGGAGGDGGNGAIGGHGPLTDDPG------------------------- Mb3541|M.bovis_AF2122/97 GQGGAGGDGGNGAIGGHGPLTDDPG------------------------- MMAR_1594|M.marinum_M GDGGTGGLGGAGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAAGTGT MUL_4367|M.ulcerans_Agy99 GDGGAGGAGGVGGLGGDSAATAGGG------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGDGIDGGLGGNGGDGVVNTTAN------------------------- TH_3810|M.thermoresistible__bu STSRSRRSFCCSRA------------------------------------ MAB_4284c|M.abscessus_ATCC_199 GGSTAVGGGAHTGVGGGVSTGVGVG------------------------- MAV_4827|M.avium_104 GGGHVPTPGAGGSGGSGGGHVPTPG------------------------- MLBr_01556|M.leprae_Br4923 GDAYGRVRRMVDEHGVDIEAALPSS------------------------- . Mflv_5091|M.gilvum_PYR-GCK ----------ATGAQGATGATGA--------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGAQGATGATGA--------------------------- Rv3512|M.tuberculosis_H37Rv -------GNGGTGGNGGTGGTGG--------------------------- Mb3541|M.bovis_AF2122/97 -------GNGGTGGNGGTGGTGG--------------------------- MMAR_1594|M.marinum_M GGIQGAGGQGGTGGTGGQGGTGGDGAESTDPTLAGQAGGQGGTGGTGGAA MUL_4367|M.ulcerans_Agy99 ----------GAGGDGGKGGAGG--------------------------- MSMEG_0868|M.smegmatis_MC2_155 ------AANPGSATGTATGGDGGKATG----------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------SHVGGGISESLGG--------------------------- MAV_4827|M.avium_104 -----------TGGPGGTGGSGG--------------------------- MLBr_01556|M.leprae_Br4923 --------PVQVIGFTSVPGAGDNFLVVD--------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -----------------AGIGSLG-------------------------- Mb3541|M.bovis_AF2122/97 -----------------AGIGSLG-------------------------- MMAR_1594|M.marinum_M GQGGTGSVAGTDGSAGDGGTGGLGGHGGAGADNTTTVSAGAQGATGGTGG MUL_4367|M.ulcerans_Agy99 -----------------AGVNGVG-------------------------- MSMEG_0868|M.smegmatis_MC2_155 ----------------TASQGGNG-------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------AGKAGATGAAGAAGAAGSA----------- Mvan_1264|M.vanbaalenii_PYR-1 --------------------SGAQGSAGSAGSAGVAGSA----------- Rv3512|M.tuberculosis_H37Rv ---------------GGTGGDGGNG---GNGGTGGEGGE----------- Mb3541|M.bovis_AF2122/97 ---------------GGTGGDGGNGGTGGNGGTGGEGGE----------- MMAR_1594|M.marinum_M AGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQIA MUL_4367|M.ulcerans_Agy99 ------------------GGDGGKGGTGGAGGAGGAGSD----------- MSMEG_0868|M.smegmatis_MC2_155 ---------------GPSWVQSGYGSTLGGNATGTATAG----------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------SGSVGGSTAVGGGAHTGVG----------- MAV_4827|M.avium_104 ----------------------GHVPTPGAGTPGGSGGG----------- MLBr_01556|M.leprae_Br4923 ---------------EDRIARQIADRRSARKRNALAARSRKRISLEDLDS Mflv_5091|M.gilvum_PYR-GCK -----GTTGAQGSAGTNG------------ANGANGSQ------------ Mvan_1264|M.vanbaalenii_PYR-1 -----GTTGAQGSAGTNG------------ANGANGSQ------------ Rv3512|M.tuberculosis_H37Rv ----VGGAGGTGGAAGNG------------GDGGTGGTGGGD-------- Mb3541|M.bovis_AF2122/97 ----VGGAGGTGGAAGNG------------GDGGTGGTGGGD-------- MMAR_1594|M.marinum_M QAGGQGGTGGTGGAAGQGGTGSTMGSAGTAGDGGTGGLGGGGGTGADNTT MUL_4367|M.ulcerans_Agy99 -----GIIPSNGGLGGNG------------GNGGNGGQAFGDG------- MSMEG_0868|M.smegmatis_MC2_155 ----KGGEASNGGVAGNGG------NALVMAAGTTGVATGNTATGGD--- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----GGVNTGVGVGSHVG------------------------------- MAV_4827|M.avium_104 ------HLPFPGAGSTPG-------------------------------- MLBr_01556|M.leprae_Br4923 ALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDR------- Mflv_5091|M.gilvum_PYR-GCK ------------------------------------GAAGKAGATGTTGA Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------GAAGKAGATGTTGA Rv3512|M.tuberculosis_H37Rv ------------------------------------GGAGGTGGTGGTGG Mb3541|M.bovis_AF2122/97 ------------------------------------GGAGGTGGTGGTGG MMAR_1594|M.marinum_M AVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGTGG MUL_4367|M.ulcerans_Agy99 -----------------------------------VGGAGGIGGKGGNAA MSMEG_0868|M.smegmatis_MC2_155 -----------------------------------GGAATTAGATGGAGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------GGISESLGGSGS MAV_4827|M.avium_104 ------------------------------------GSGGGHLPTPGAGT MLBr_01556|M.leprae_Br4923 ------------------------------------GVGGITETNVNLAS Mflv_5091|M.gilvum_PYR-GCK TG------------------------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 TG------------------------------------------------ Rv3512|M.tuberculosis_H37Rv LGDP---------------------------------------------- Mb3541|M.bovis_AF2122/97 LGDP---------------------------------------------- MMAR_1594|M.marinum_M IGGTGTDSTDPTLAGQAGGQGGTGGTGGAAGTGGTGSVTGTDGTAGDGGT MUL_4367|M.ulcerans_Agy99 IGTIVIN------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 FSNIAAIH------------------------------------------ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VG------------------------------------------------ MAV_4827|M.avium_104 PG------------------------------------------------ MLBr_01556|M.leprae_Br4923 ASDAIIIG------------------------------------------ Mflv_5091|M.gilvum_PYR-GCK ---------------------------AAGEDGDAGSGGSGIN------- Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------AAGDAGDPGSEAVDIN------- Rv3512|M.tuberculosis_H37Rv -----------------------RVGGSGGDGGTGGSGGAAGN------- Mb3541|M.bovis_AF2122/97 -----------------------RVGGSGGDGGTGGSGGAAGN------- MMAR_1594|M.marinum_M GGLGGHGGAGADNTTTVSAGAQGATGGTGGAGGTGGTGGAAGTGTGGTQG MUL_4367|M.ulcerans_Agy99 -------------------------GGVGGAGGSGGLGGATED------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------GAITDSTAISGHGGAGNG------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------GSTAVGGGAHTSAIN------- MAV_4827|M.avium_104 ----------------------------GGLGGFGGGHAPAPG------- MLBr_01556|M.leprae_Br4923 ----------------------FNVRAEGKATELASREGVEIR------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv --------------------------------------GGNGGNAGAGGN Mb3541|M.bovis_AF2122/97 --------------------------------------GGNGGNAGAGGN MMAR_1594|M.marinum_M AGGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGSGGT MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1594|M.marinum_M GSVTGTDGTAGDGGTGGLGGDGGAGADNTTTVSAGAQGATGGTGGAGGQG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------GGAGGAGGAGG--EGGEGGD--------GGK Mvan_1264|M.vanbaalenii_PYR-1 -------------------GGAGGAGGAGG--EGGEGGA--------GGA Rv3512|M.tuberculosis_H37Rv -----------------GNGGTGGAGGIGG--TGGNGGD--AEPGVPPGA Mb3541|M.bovis_AF2122/97 -----------------GNGGTGGAGGIGG--TGGNGGD--AEPGVPPGA MMAR_1594|M.marinum_M GTGGAAGTGTGGIQGAGGQGGTGGAGGSGG--TGGDGTDNSTTPGAAGGA MUL_4367|M.ulcerans_Agy99 -----------------GVGGVGCAGGAGG--NGG-RGDMLFTVGGSGGT MSMEG_0868|M.smegmatis_MC2_155 -----------------GNGGKGADGWVQAYDPAGPVGSKIANSSAVAGN TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------DALGGSGSVGGSTAVGGGAHTSAINESMNSS MAV_4827|M.avium_104 -------------------GGLGGGGGHAP---------------APGGG MLBr_01556|M.leprae_Br4923 --------YYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSK Mflv_5091|M.gilvum_PYR-GCK GGAGAEGGAGGG-GGAGGSG-------AGGAGGAG--------------- Mvan_1264|M.vanbaalenii_PYR-1 GGDGSEGGAGGS-GGAGGSG-------TGGAGGAG--------------- Rv3512|M.tuberculosis_H37Rv GGAGGAGTTGGK-GGTGGNGSGTGSGGTGGDGGTG--------------- Mb3541|M.bovis_AF2122/97 GGAGGAGTTGGK-GGTGGNGSGTGSGGTGGDGGTG--------------- MMAR_1594|M.marinum_M GGQGGTGGTGGA-AGQGGTGSTMGSDGSSGDGGTGGLGGDGGGAGQGTTG MUL_4367|M.ulcerans_Agy99 GGDGGGGGSASG-SGTGGSGGTGGVGGIGGDGKLG--------------- MSMEG_0868|M.smegmatis_MC2_155 GGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADG--------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 INASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQG--------------- MAV_4827|M.avium_104 LGGFGGGHSGGGLGGLGGGHK----------------------------- MLBr_01556|M.leprae_Br4923 VGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLR----------- Mflv_5091|M.gilvum_PYR-GCK ---------------------------------GSGGSGGSGGSGG---- Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------GSGGSGGSGGAGG---- Rv3512|M.tuberculosis_H37Rv ---------------------------------GGGGNGGTGWNGGKGDT Mb3541|M.bovis_AF2122/97 ---------------------------------GGGGNGGTGWNGGKGDT MMAR_1594|M.marinum_M TAGAGTGGQGASGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGTGGT MUL_4367|M.ulcerans_Agy99 ---------------------------------GFGGDGGDGGDGGFGVI MSMEG_0868|M.smegmatis_MC2_155 -------------------------------EHNTGGNGGNGGDGSEPGP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------------------HASETAHTTLPGAEHH- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ---------------------------------REKDDVTEVREGFECGM Mflv_5091|M.gilvum_PYR-GCK ------------------------SGGAAGDSDD---------------- Mvan_1264|M.vanbaalenii_PYR-1 ------------------------SGGAAGDSD----------------- Rv3512|M.tuberculosis_H37Rv G-----------------------SGGGAGDGGK---------------- Mb3541|M.bovis_AF2122/97 G-----------------------SGGGAGDGGK---------------- MMAR_1594|M.marinum_M GGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTGSTMGAEGSSGDGGTG MUL_4367|M.ulcerans_Agy99 GG----------------------QGGGGGFGGLG--------------- MSMEG_0868|M.smegmatis_MC2_155 GGNG--------------------AGGAGGNGGTG--------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 TLG--------------------YSDIKEGDVIESYELVEKQRA------ Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv ---------------------APAGGTGGAGGDG--------------GA Mb3541|M.bovis_AF2122/97 ---------------------APAGGTGGAGGDG--------------GA MMAR_1594|M.marinum_M GLGGHGGAGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGTQGA MUL_4367|M.ulcerans_Agy99 -----------------------GTGAGGAPSDK--------------GI MSMEG_0868|M.smegmatis_MC2_155 ------------------GTTAGGSGNGGNGGNG--------------GN TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv GGKGGSGGV----------------------------------------- Mb3541|M.bovis_AF2122/97 GGKGGSGGV----------------------------------------- MMAR_1594|M.marinum_M GGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTG MUL_4367|M.ulcerans_Agy99 NGEPGNPG------------------------------------------ MSMEG_0868|M.smegmatis_MC2_155 GGADGTPGTAGTTGANNP-------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1594|M.marinum_M STMGSAGTAGDGGTGGLGGGGGTGADNTTTVSAGAQGATGGTGGAGGQGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1594|M.marinum_M TGGAAGTGTGGIQGAGGQGGTGGTGGTGGIGGTGTDSTDPTLAGQAGGQG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---------------- Mvan_1264|M.vanbaalenii_PYR-1 ---------------- Rv3512|M.tuberculosis_H37Rv ---------------- Mb3541|M.bovis_AF2122/97 ---------------- MMAR_1594|M.marinum_M GTGETGGAAGSGGTGS MUL_4367|M.ulcerans_Agy99 ---------------- MSMEG_0868|M.smegmatis_MC2_155 ---------------- TH_3810|M.thermoresistible__bu ---------------- MAB_4284c|M.abscessus_ATCC_199 ---------------- MAV_4827|M.avium_104 ---------------- MLBr_01556|M.leprae_Br4923 ----------------