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M. bovis AF2122 / 97 Mb0572 (pimB)

annotation: mannosyltransferase PIMB
coordinates: 649779 - 650915
length: 378

VCGVRVAIVAESFLPQVNGVSNSVVKVLEHLRRTGHEALVIAPDTPPGEDRAERLHDGVRVHRVPSRMFP
KVTTLPLGVPTFRMLRALRGFDPDVVHLASPALLGYGGLHAARRLGVPTVAVYQTDVPGFASSYGIPMTA
RAAWAWFRHLHRLADRTLAPSTATMESLIAQGIPRVHRWARGVDVQRFAPSARNEVLRRRWSPDGKPIVG
FVGRLAPEKHVDRLTGLAASGAVRLVIVGDGIDRARLQSAMPTAVFTGARYGKELAEAYASMDVFVHSGE
HETFCQVVQEALASGLPVIAPDAGGPRDLITPHRTGLLLPVGEFEHRLPDAVAHLVHERQRYALAARRSV
LGRSWPVVCDELLGHYEAVRGRRTTQAA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0572pimB-100% (378)mannosyltransferase PIMB
M. bovis AF2122 / 97Mb1785c-4e-1529.50% (322) hypothetical protein Mb1785c
M. bovis AF2122 / 97Mb2211c-3e-1226.98% (378) hypothetical protein Mb2211c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5260-1e-16876.80% (375) glycosyl transferase, group 1
M. tuberculosis H37RvRv0557pimB0.0100.00% (378) mannosyltransferase PIMB
M. leprae Br4923MLBr_00886-7e-1527.27% (374) putative glycosyl transferase
M. abscessus ATCC 19977MAB_3931c-1e-14367.84% (370) glycosyl transferase
M. marinum MMMAR_0903pimB1e-18084.43% (366) mannosyltransferase, PimB
M. avium 104MAV_4586-0.086.61% (366) glycosyl transferase
M. smegmatis MC2 155MSMEG_1113-1e-16574.93% (375) glycosyl transferase
M. thermoresistible (build 8)TH_1121-1e-16577.32% (366) MANNOSYLTRANSFERASE PIMB
M. ulcerans Agy99MUL_0656pimB1e-17783.33% (366) mannosyltransferase, PimB
M. vanbaalenii PYR-1Mvan_0978-1e-16674.67% (375) glycosyl transferase, group 1

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5260|M.gilvum_PYR-GCK          ---MRVAIVAESFLPNVNGVTNSVLRVIEHLRRTG-HEALVIAPDTPRGE
Mvan_0978|M.vanbaalenii_PYR-1       ---MRVAIVAESFLPNVNGVTNSVLRVIEHLRRTG-HEVLVIAPDTPRGQ
MSMEG_1113|M.smegmatis_MC2_155      ---MRVAIVAESFLPNVNGVTNSVLRVIDHLRRTG-HEVLVIAPDTPRGQ
TH_1121|M.thermoresistible__bu      ---VRVAIVTESFLPHVNGVTNSVLRVVEHLRGTG-HEVLVIAPDTPPGQ
Mb0572|M.bovis_AF2122/97            MCGVRVAIVAESFLPQVNGVSNSVVKVLEHLRRTG-HEALVIAPDTPPGE
Rv0557|M.tuberculosis_H37Rv         MCGVRVAIVAESFLPQVNGVSNSVVKVLEHLRRTG-HEALVIAPDTPPGE
MAV_4586|M.avium_104                ---MRVAIVAESFLPEVNGVSNSVIRVLEHLRRTG-HEALVIAPDTPPGQ
MMAR_0903|M.marinum_M               ---MRVAIVAESFLPNVNGVSNSVVRVLEHLRRTG-HEALVIAPDNPPGE
MUL_0656|M.ulcerans_Agy99           ---MRVAIVAESFLPNVNGVSNSVVRVLEHLRRTG-HEALVIAPDNPPGE
MAB_3931c|M.abscessus_ATCC_199      ---MRIAIVAESFLPNVNGVSNSVLRVLEHFRRTG-HEAIVIAPDTPRGQ
MLBr_00886|M.leprae_Br4923          --MSRVLLVTNDFPPRRGGIQSYLGEFVDRLINIGSHDVMVYAPQWTGAD
                                        *: :*::.* *. .*: . : ..::::   * *:.:* **: . .:

Mflv_5260|M.gilvum_PYR-GCK          PPADRVYDGVRVHRVPSAMFPKVTSLPLGVPRPRMVGVLRGFDPDVVHLA
Mvan_0978|M.vanbaalenii_PYR-1       PAADKVYEGVRVHRVPSMMFPKITSLPLGVPRPRMVGVLRGFDPDVVHLA
MSMEG_1113|M.smegmatis_MC2_155      PPADRIHDGVRVHRVPSRMFPKITSLPLGVPRPRMIGVLRGFDPDVVHLA
TH_1121|M.thermoresistible__bu      PPAERVHDGVRIHRVPSRMFPKITSLPLGIPRPRMIGVLRGFDPDVVHLA
Mb0572|M.bovis_AF2122/97            DRAERLHDGVRVHRVPSRMFPKVTTLPLGVPTFRMLRALRGFDPDVVHLA
Rv0557|M.tuberculosis_H37Rv         DRAERLHDGVRVHRVPSRMFPKVTTLPLGVPTFRMLRALRGFDPDVVHLA
MAV_4586|M.avium_104                PRAERIHDGIRVHRVPSRMFPKVTTLPLGVPTPRLVSVLRGFDPHVVHLA
MMAR_0903|M.marinum_M               PRADRLHDGVRVHRTPARMFPKVTTLPLGVPTPRILRVLRGFEPDVVHLA
MUL_0656|M.ulcerans_Agy99           PRADRLHDGVRVHRTPARMFPEVTTLPLGVPTPRILRVLRGFEPDVVHLA
MAB_3931c|M.abscessus_ATCC_199      APAATEYAGVPVHRVPAIMFPKVSTLPLGVPQPRMVRIFREFAPDVVHLA
MLBr_00886|M.leprae_Br4923          TFDNAAHDGG----YQVVRHPGTLMLPGPAVDARMRRLIVDHGIDTVWFG
                                          : *          .*    **      *:   :  .  ..* :.

Mflv_5260|M.gilvum_PYR-GCK          SPALLGWGGVHAARHLGVPTVAVFQTDVAGFAQSYGIGMMSRASWAWTRR
Mvan_0978|M.vanbaalenii_PYR-1       SPALLGWGGVHAARRLGIPTVAVFQTDVAGFAESYGIGMLSHASWAWTRR
MSMEG_1113|M.smegmatis_MC2_155      SPALLGYGGLHAARHLGVPSVAVFQTDVAGFAESYGMGVASRAAWAWTRH
TH_1121|M.thermoresistible__bu      SPALLGYGGLLAARRLRVPTVAVFQTDVAGFAASYGMGVAARAAWAWTRH
Mb0572|M.bovis_AF2122/97            SPALLGYGGLHAARRLGVPTVAVYQTDVPGFASSYGIPMTARAAWAWFRH
Rv0557|M.tuberculosis_H37Rv         SPALLGYGGLHAARRLGVPTVAVYQTDVPGFASSYGIPMTARAAWAWFRH
MAV_4586|M.avium_104                SPALLGYGGLRAARWLGVPTVAVYQTDVPGFAASYGIPMTARAAWAWFRH
MMAR_0903|M.marinum_M               SPALLGYGALRAARRLGVPTVAVYQTDVPGFAASYGIAATSRAAWAWFRH
MUL_0656|M.ulcerans_Agy99           SPALLGYGALRAARRLGVPTVAVYQTDVLGFAASYGIAATSRAAWAWFRH
MAB_3931c|M.abscessus_ATCC_199      SPFVLGYGGLRAAQHLDVPVVAVYQTDVAGFADSYGAGFAARAAWRWTKH
MLBr_00886|M.leprae_Br4923          SAAPLALLAPCARKAGATRVLASTHGHEVGWSMLPVARSVLRRIGDVTDV
                                    *.  *.  .  * :      :*  : .  *::         :        

Mflv_5260|M.gilvum_PYR-GCK          LHSKADRTLAPSTSAMENLAAHGIPRVHKWARGVDVTGFAP-SARDQRLR
Mvan_0978|M.vanbaalenii_PYR-1       LHSKADRTLAPSTSAMENLAAHRIPRVHKWARGVDVTGFAP-SARDERLR
MSMEG_1113|M.smegmatis_MC2_155      LHSRADRTLAPSTSAMENLAAHRIPRVHRWGRGVDITGFVP-SARDEHLR
TH_1121|M.thermoresistible__bu      LHRLADRTLAPSTAAMRDLARHGVPRVHLWARGVDVGGFAP-SARDEQLR
Mb0572|M.bovis_AF2122/97            LHRLADRTLAPSTATMESLIAQGIPRVHRWARGVDVQRFAP-SARNEVLR
Rv0557|M.tuberculosis_H37Rv         LHRLADRTLAPSTATMESLIAQGIPRVHRWARGVDVQRFAP-SARNEVLR
MAV_4586|M.avium_104                LHTLADRTLAPSTVTMESLVAHRFPRVHRWARGVDVLRFAP-SARSEALR
MMAR_0903|M.marinum_M               LHGLADRTLAPSTPTMQTLLDQGFPRVHRWARGVDLIRFAP-SARDESLR
MUL_0656|M.ulcerans_Agy99           LHGLADRTLAPSTPTMQTLLDQGFPRVHRWARGVDLIRFAP-SARDESLR
MAB_3931c|M.abscessus_ATCC_199      LHGRADRTLAPSSSAMEDLAMHGIPRVFRWSRGVDIERFAP-SARDDELR
MLBr_00886|M.leprae_Br4923          VTFVSRYTRSRVTAAFGPRAALEY-----LPPGVDADRFRPDPASRAELR
                                    :   :  * :  : ::                ***   * * .*    **

Mflv_5260|M.gilvum_PYR-GCK          QSWSPQGKPIVGFVGRLAPEKH----VERLAPLHARDD-IQLVIVGDGVD
Mvan_0978|M.vanbaalenii_PYR-1       RSWSPDGRPIIGFVGRLAPEKH----VERLAALHARDD-LQIVVVGDGVD
MSMEG_1113|M.smegmatis_MC2_155      RTWSPDGRPIVGFVGRLAPEKH----VERLAVLAARDD-LQLVIVGDGVD
TH_1121|M.thermoresistible__bu      RRWSPDGKPIVGFVGRLAPEKH----VERLRALAPRTD-LQLVIVGDGVD
Mb0572|M.bovis_AF2122/97            RRWSPDGKPIVGFVGRLAPEKH----VDRLTGLAASGA-VRLVIVGDGID
Rv0557|M.tuberculosis_H37Rv         RRWSPDGKPIVGFVGRLAPEKH----VDRLTGLAASGA-VRLVIVGDGID
MAV_4586|M.avium_104                RRWSPQGKPIVGFVGRLAPEKH----VERLAGLAASDA-VQLVVVGDGVD
MMAR_0903|M.marinum_M               RRWSPDGRPIVGFVGRLAPEKH----AERLAGLAASGA-VTLVIVGAGVD
MUL_0656|M.ulcerans_Agy99           RRWSPDGRPIVGFVGRLAPEKD----AERLAGLAASGA-VTLVIVGAGVD
MAB_3931c|M.abscessus_ATCC_199      RAWSPKGKPIIGFVGRLAPEKH----VERLAVLAGRDD-LQLVIVGGGVE
MLBr_00886|M.leprae_Br4923          NRYRLGERPTVVCLARLVPRKGQDMLIRALPSIRQRADGAALMIVGGGPY
                                    . :    :* :  :.**.*.*        *  :        :::** *  

Mflv_5260|M.gilvum_PYR-GCK          RARLESAFP------RAVFTGALYGPELAAAYASMDVFVHGG-------E
Mvan_0978|M.vanbaalenii_PYR-1       RAKLESELP------RAVFTGALYGDELAAAYASMDVFVHPG-------E
MSMEG_1113|M.smegmatis_MC2_155      RVKLQTVLP------TAVFTGELRGAALAAAYASMDVFVHPG-------E
TH_1121|M.thermoresistible__bu      RRKLENLLP------TAVFTGALYGEQLAAAYASMDVFVHPG-------E
Mb0572|M.bovis_AF2122/97            RARLQSAMP------TAVFTGARYGKELAEAYASMDVFVHSG-------E
Rv0557|M.tuberculosis_H37Rv         RARLQSAMP------TAVFTGARYGKELAEAYASMDVFVHSG-------E
MAV_4586|M.avium_104                RAKLQSAMP------TAVFTGALYGDELAAAYASMDVFVHPG-------E
MMAR_0903|M.marinum_M               RRKLELAMP------TAVFTGALYGDELAAAYASMDVFVHAG-------E
MUL_0656|M.ulcerans_Agy99           RRKLELAMP------TAVFTGALYGDELAAAYASMDVFVHAG-------E
MAB_3931c|M.abscessus_ATCC_199      REALEKLMP------TAVFTGELTGSALSRAYASLDVFIHPG-------E
MLBr_00886|M.leprae_Br4923          LGTLRKLAQGCGVADHVIFAGGVAAVEVPAHYTLADVFAMPCRTRGGGMD
                                       *.           .:*:*   .  :.  *:  ***           :

Mflv_5260|M.gilvum_PYR-GCK          HETFCQAVQEAMASGLPVIAPDAGGPRDLVAPYRSGLLLPVAEFEDRLSE
Mvan_0978|M.vanbaalenii_PYR-1       HETFCQAVQEAMASGLPVIAPDAGGPRDLVAPYRTGLLLPVAEFESRLAE
MSMEG_1113|M.smegmatis_MC2_155      HETFCQTVQEAMASGVPVIAPDAGGPRDLVAPCRTGLLLDVDGFECALPA
TH_1121|M.thermoresistible__bu      HETFCQAVQEALASGLPVIAPDAGGPRDLVAPCRTGLLLPVEEFETRLAG
Mb0572|M.bovis_AF2122/97            HETFCQVVQEALASGLPVIAPDAGGPRDLITPHRTGLLLPVGEFEHRLPD
Rv0557|M.tuberculosis_H37Rv         HETFCQVVQEALASGLPVIAPDAGGPRDLITPHRTGLLLPVGEFEHRLPD
MAV_4586|M.avium_104                HETFCQVVQEALASGLPVIAPDAGGPRDLVTPWRTGLLLAVDEFETKLPA
MMAR_0903|M.marinum_M               HETFCQVVQEALASGLPVIAPDAGGPRDLVTPQRTGLLLPVDGFETQLPA
MUL_0656|M.ulcerans_Agy99           HETFCQVVQEALASGLPVIAPDAGGPRDLVAPQRTGLLLPVDGFETQLPA
MAB_3931c|M.abscessus_ATCC_199      HETFCQAVQEALASGVPSIAPDAGGPRDLVIPGRNGMLLPVADFEARLGM
MLBr_00886|M.leprae_Br4923          VEGLGIVFLEASATGVPVIAGKSGGAPEAVQHNKTGLVVDGRSVN-MVAD
                                     * :  .. ** *:*:* ** .:**. : :   :.*:::    .:  :  

Mflv_5260|M.gilvum_PYR-GCK          SVDHLVV--ERRRYSQAARRSVLGRTWPVICDELVGHYEAVVG---ARAL
Mvan_0978|M.vanbaalenii_PYR-1       SVDHLVA--ERRRYSVAARRSVLGRTWPVICDELLGHYEAVMG---ARRL
MSMEG_1113|M.smegmatis_MC2_155      AVTHLIA--ERRRYGIAARRSVLARTWPVVCDELIGHYEAVLG---RRSL
TH_1121|M.thermoresistible__bu      AVDHLLA--ERPRYAVAARRSVLGRTWPAICDQLLEHYAAVXX---AVAH
Mb0572|M.bovis_AF2122/97            AVAHLVH--ERQRYALAARRSVLGRSWPVVCDELLGHYEAVRG---RRTT
Rv0557|M.tuberculosis_H37Rv         AVAHLVH--ERQRYALAARRSVLGRSWPVVCDELLGHYEAVRG---RRTT
MAV_4586|M.avium_104                AVAHLIG--ERHRYAPAARRSVLGRSWPVICDELLGHYEAVLSPFVRRQV
MMAR_0903|M.marinum_M               AVAHLVH--ERQRYSQAARRSVLGRSWSVICDELLDHYAEVLAPTGRAQD
MUL_0656|M.ulcerans_Agy99           AVAHLVH--ERQRYSQAARRSVLGRSWSVICDELLDHYAEVLAPTGRAQD
MAB_3931c|M.abscessus_ATCC_199      AVDHLVQPATRSRFSAAARRGVLARTWPAICDELLEHYAAAAGTTLGRGI
MLBr_00886|M.leprae_Br4923          AVTELLTDRDRAAAMGAAGRHWVTAEWR--WDTLAARLADLLCGNDSR--
                                    :* .*:    *     ** *  :   *    * *  :             

Mflv_5260|M.gilvum_PYR-GCK          RAA------
Mvan_0978|M.vanbaalenii_PYR-1       RAA------
MSMEG_1113|M.smegmatis_MC2_155      RAA------
TH_1121|M.thermoresistible__bu      PAPHRHAG-
Mb0572|M.bovis_AF2122/97            QAA------
Rv0557|M.tuberculosis_H37Rv         QAA------
MAV_4586|M.avium_104                RAGRYAQGE
MMAR_0903|M.marinum_M               WLWRRRRA-
MUL_0656|M.ulcerans_Agy99           WLWRRRRA-
MAB_3931c|M.abscessus_ATCC_199      MTA------
MLBr_00886|M.leprae_Br4923          ---------