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MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDARVVILFSDIEESTALDE RIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCGIDIQDALRNSAKRKRNQGI RVRIGTTWGARCGTVTICSAATSQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1151c | - | - | 100% (164) | hypothetical protein Mb1151c |
| M. bovis AF2122 / 97 | Mb1935c | lipJ | 6e-10 | 37.08% (89) | lignin peroxidase LIPJ |
| M. bovis AF2122 / 97 | Mb2515c | - | 3e-08 | 33.33% (117) | LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2091 | - | 7e-51 | 65.10% (149) | putative adenylate/guanylate cyclase |
| M. tuberculosis H37Rv | Rv1120c | - | 1e-91 | 99.39% (164) | hypothetical protein Rv1120c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4340 | - | 8e-67 | 83.22% (149) | hypothetical protein MMAR_4340 |
| M. avium 104 | MAV_1250 | - | 2e-64 | 79.87% (149) | adenylate and guanylate cyclase catalytic domain-containing |
| M. smegmatis MC2 155 | MSMEG_4477 | - | 5e-05 | 32.18% (87) | hydrolase, alpha/beta hydrolase fold family protein |
| M. thermoresistible (build 8) | TH_1244 | - | 1e-49 | 63.09% (149) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0150 | - | 5e-66 | 81.88% (149) | hypothetical protein MUL_0150 |
| M. vanbaalenii PYR-1 | Mvan_4613 | - | 1e-49 | 66.21% (145) | putative adenylate/guanylate cyclase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4613|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1244|M.thermoresistible__bu --------------------------------------------------
Mb1151c|M.bovis_AF2122/97 --------------------------------------------------
Rv1120c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4340|M.marinum_M --------------------------------------------------
MUL_0150|M.ulcerans_Agy99 --------------------------------------------------
MAV_1250|M.avium_104 --------------------------------------------------
MSMEG_4477|M.smegmatis_MC2_155 MAETSYASCGDLSLAYQLFGDGPIPLVFVGPFVGHVELFWTVPEFKSFFD
Mflv_2091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4613|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1244|M.thermoresistible__bu -----------------------------VAARPLPLAVAAAPGSPIPRR
Mb1151c|M.bovis_AF2122/97 --------------------------------------------------
Rv1120c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4340|M.marinum_M --------------------------------------------------
MUL_0150|M.ulcerans_Agy99 --------------------------------------------------
MAV_1250|M.avium_104 --------------------------------------------------
MSMEG_4477|M.smegmatis_MC2_155 QLASFCRVAIFDKAGTGLSDPVPKVRTLDDRAAEIEAVMDAVGFDDAVVL
Mflv_2091|M.gilvum_PYR-GCK ---------MLILVCVLAVLAAGLGIALAVQTRRLTSARQEAEELRHRLD
Mvan_4613|M.vanbaalenii_PYR-1 -----------MALLVLAAVVVGLAVALAVQSRRLRTARQEADELRRRLD
TH_1244|M.thermoresistible__bu VGQDGAVTQIAIVVVALAGLALAEAVALAVLWGRLRRERRAADELRRRLD
Mb1151c|M.bovis_AF2122/97 --------------------------------------------------
Rv1120c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4340|M.marinum_M -----MTDALHIAVYVLAGVAALEAAALIALWRLLARARQENDELRQRAD
MUL_0150|M.ulcerans_Agy99 --------------------------------------------MRQRAD
MAV_1250|M.avium_104 -----MGDVLHVTVYILAGLAAVEAGALAVLWRRLVRSRAELDELRQRTD
MSMEG_4477|M.smegmatis_MC2_155 AMSEGGPASILFAANRPGRVRTLVAYGSFATMAGCRWEDLDGDPVDIRAR
Mflv_2091|M.gilvum_PYR-GCK TRQLLVSGGTKAVKTVWQTANILRKD----GFGAAVRSSIEEL-------
Mvan_4613|M.vanbaalenii_PYR-1 TRQMLVTGSTKAVKTVWQTANILRRD----GFGAAVRSSIEEL-------
TH_1244|M.thermoresistible__bu TRTTLMAGGREAVRTVWQTANILRTD----GLGAAARSSIEDL-------
Mb1151c|M.bovis_AF2122/97 ----MLSGGREAVKTVWQTANLVRKE----GFGAAVRSSIEDP-------
Rv1120c|M.tuberculosis_H37Rv ----MLSGGREAVKTVWQTANLVRKE----GFGAAVRSSIEDP-------
MMAR_4340|M.marinum_M SRNWLLTGGREAVKTVWQTANLMRKE----GFGAAVRSSIEDL-------
MUL_0150|M.ulcerans_Agy99 SRNWLLTGGREAVKTVWQTANLMRKE----GFGAAVRSSIEDL-------
MAV_1250|M.avium_104 ARNWLLAGGREAVKTVWNTANLVRKE----GFGAAVRSSIEEL-------
MSMEG_4477|M.smegmatis_MC2_155 SVAEMGDEYAPTVEQVIHFQEQARAVRGQWGSGAAVRCAMPSMGSMRQLG
: :*. * : : * * ***.*.:: .
Mflv_2091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4613|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1244|M.thermoresistible__bu --------------------------------------------------
Mb1151c|M.bovis_AF2122/97 --------------------------------------------------
Rv1120c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4340|M.marinum_M --------------------------------------------------
MUL_0150|M.ulcerans_Agy99 --------------------------------------------------
MAV_1250|M.avium_104 --------------------------------------------------
MSMEG_4477|M.smegmatis_MC2_155 MFERLCASPGMARATFEAAFRIDVRPILPTIAAPTLVIHARDDPAVPVQC
Mflv_2091|M.gilvum_PYR-GCK ----------ADWAEVERPDLARLSLNGR---------------------
Mvan_4613|M.vanbaalenii_PYR-1 ----------ADWAEVERPDLARLAPNGR---------------------
TH_1244|M.thermoresistible__bu ----------ADWAEVERPDLARLAANGK---------------------
Mb1151c|M.bovis_AF2122/97 ----------ADWAEVERPDLARVTPDAR---------------------
Rv1120c|M.tuberculosis_H37Rv ----------ADWAEVERPDLARVTPDGR---------------------
MMAR_4340|M.marinum_M ----------ADWAEVERPDLARVTPDGR---------------------
MUL_0150|M.ulcerans_Agy99 ----------ADWAEVERPDLARVTPDGR---------------------
MAV_1250|M.avium_104 ----------ADWAEVERPDLARVTPDGR---------------------
MSMEG_4477|M.smegmatis_MC2_155 SRYLADHISGARWLEVDGVDHAPWFTEADRVLTEIEEFVTGNHAAPHNSH
* * **: * * :.
Mflv_2091|M.gilvum_PYR-GCK ---LTIMFSDIEESTALNERIGDRAFVRLIGRHDKSVRKFVDKHEGHVVK
Mvan_4613|M.vanbaalenii_PYR-1 ---VAIMFSDIEESTALNERIGDRAFVRLLGRHDKPVRRHVDAHDGYVVK
TH_1244|M.thermoresistible__bu ---VVILFSDIEGSTALNNRIGDRAWVRLIDRHSRLVRRFVKKHDGYVIK
Mb1151c|M.bovis_AF2122/97 ---VVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVT
Rv1120c|M.tuberculosis_H37Rv ---VVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVT
MMAR_4340|M.marinum_M ---VVILFSDIEESTALNERIGDRAWVKLIGAHDKMVHEFVHRHGGHVVK
MUL_0150|M.ulcerans_Agy99 ---VVILFSDIEESTVLNERIGNRAWVKLIGAHDKMVHEFVHRHGGHVVK
MAV_1250|M.avium_104 ---VVILFTDIEESTALNERIGDRAWVKLISSHDKLVSDLVRRQSGHVVK
MSMEG_4477|M.smegmatis_MC2_155 RALRTVLFTDIVASTQHAASNGDERWRAVLQRFGEVTEELSGRFGGVVVK
.::*:** ** *:. : :: ... . * ::.
Mflv_2091|M.gilvum_PYR-GCK SQGDGFMVAFAKPEQAVRCGLDIQHSLA-----RRPNDIRVRMGVHTGKS
Mvan_4613|M.vanbaalenii_PYR-1 SQGDGFMVAFARPEQAVRCGLAIQHSLD-----KRPNGIRVRIGIHVGKS
TH_1244|M.thermoresistible__bu SQGDGFMVAFARPEQAVRCSVELQRALR-----KRPDRIRVRIGIHLGRS
Mb1151c|M.bovis_AF2122/97 SQGDGFMIAFARAEQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWG--
Rv1120c|M.tuberculosis_H37Rv SQGDGFMIAFARAEQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWG--
MMAR_4340|M.marinum_M SQGDGFMIAFARAEQAVRCGLDIQRALSREAKRKPRNGIRVRIGIHMGRS
MUL_0150|M.ulcerans_Agy99 SQGDGFMIAFARAEQAVRCGLDIQHALSREAKRKPRNGIRVRIGIHMGRS
MAV_1250|M.avium_104 SQGDGFMVAFARPEQAVRCGIELQRALRRNANRKRHEEIRVRIGIHMGRS
MSMEG_4477|M.smegmatis_MC2_155 STGDGHLSTFEGPTHAIRYAEALRSDAET-------LGIQIRAAIHTGEC
* ***.: :* . :*:* . :: *::* . *
Mflv_2091|M.gilvum_PYR-GCK VLRGDDVFGRNVAMAARVAAAADGGEILVSSAVHRALADCEDLA------
Mvan_4613|M.vanbaalenii_PYR-1 VLRGDDLFGRNVAMAARVAAEADGGEVLVSSAVRDALTDADDIV------
TH_1244|M.thermoresistible__bu VRRGDDLFGRNVALAARVAGAAEGGEVLVSQAVRDALNSAGDAGSDEVAG
Mb1151c|M.bovis_AF2122/97 ARCG------TVTICSAATSQ-----------------------------
Rv1120c|M.tuberculosis_H37Rv ARCG------TVTICSAATSQ-----------------------------
MMAR_4340|M.marinum_M VRRGDDLFGRNVAMAARVAGQAGGGQILVSEPVRDAVRDCGDIR------
MUL_0150|M.ulcerans_Agy99 VRRGDDLFGRNVAMAARVAGQAVGGQILVSEPVRDAVRDCGDIR------
MAV_1250|M.avium_104 VRRGDDLFGRNVAMAARVAAQAAGGEILVSQPVRDALSRSDGIR------
MSMEG_4477|M.smegmatis_MC2_155 ELLGDDIGGIAVHIAARILGQARAGEILVSRTVRDLVVGSGTSF------
* * :.: .
Mflv_2091|M.gilvum_PYR-GCK --FDEQRDVELKGFSGSHTLYPVRSASASR--------------------
Mvan_4613|M.vanbaalenii_PYR-1 --VDGERDAHLKGFSGSHTLYSVRSASASR--------------------
TH_1244|M.thermoresistible__bu FDVDDGREVSLKGFPGRHRLFAVRGQAGFRPRPRPE--------------
Mb1151c|M.bovis_AF2122/97 --------------------------------------------------
Rv1120c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4340|M.marinum_M --VDDGRDVELKGFSGSYRLFGVETAPECEPD------------------
MUL_0150|M.ulcerans_Agy99 --VDDGRDVELKGFSGSYRLFGVETAPECEPD------------------
MAV_1250|M.avium_104 --FDDGREVELKGFSGTYRLFAVLASPDPG--------------------
MSMEG_4477|M.smegmatis_MC2_155 ---ADRGNVELRGVPGTWQLLAVGDGAGGGSPAGSVEALLAAEPTPAART
Mflv_2091|M.gilvum_PYR-GCK ---------------------------------
Mvan_4613|M.vanbaalenii_PYR-1 ---------------------------------
TH_1244|M.thermoresistible__bu ---------------------------------
Mb1151c|M.bovis_AF2122/97 ---------------------------------
Rv1120c|M.tuberculosis_H37Rv ---------------------------------
MMAR_4340|M.marinum_M ---------------------------------
MUL_0150|M.ulcerans_Agy99 ---------------------------------
MAV_1250|M.avium_104 ---------------------------------
MSMEG_4477|M.smegmatis_MC2_155 ATRRADRAVAAVAKRTPWALRGVARLTMSATRR