For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSWVMVSPELVVAAAADLAGIGSAISSANAAAAVNTTGLLTAGADEVSTAIAALFGAQGQAYQAASAQAA AFYAQFVQALSAGGGAYAAAEAAAVSPLLAPINAQFVAATGRPLIGNGANGAPGTGANGGPGGWLIGNGG AGGSGAPGAGAGGNGGAGGLFGSGGAGGAGGNAFGAGEVGGAGGAGGNAMLFGAGGAGGAGGAGGNAGML FGAAGVGGVGGFSNGGATGGAGGAGGAGGLFTTGGVGGAGGAGGDGGDGGAGGLFGAGGTGGAGGFGTAV LAGTGGAGGPGGAGGLFGAGGEGGSGGSGNLTGGAGGAGGNAGTLATGDGGAGGTGGASRSGGFGGAGGA GGDAGMFFGSGGSGGAGGAGGSGGFGLPSGGKGGAGGDAGMLFGSGGSGGAGGISRSVGDGAAGGAGGAP GLIGNGGNGGNGGASTGGGDGGPGGAGGTGVLIGNGGSGGTGATLGKAGIGGTGGVLLGLDGFTAPASTS PLHTLQQDVINMVNDPFQTLTGRPLIGNGANGTPGTGADGGAGGWLFGNGGNGGQGTIGGVNGGAGGAGG AGGILFGTGGTGGSGGPGATGLGGIGGAGGAALLFGSGGAGGSGGAGAVGGNGGAGGNAGALLGAAGAGG AGGAGAVGGNGGAGGNGGLFANGGAGGPGGFGSPAGAGGIGGAGGNGGLFGAGGTGGAGGGSTLAGGAGG AGGNGGLFGAGGTGGAGSHSTAAGVSGGAGGAGGDAGLLSLGASGGAGGSGGSSLTAAGVVGGIGGAGGL LFGSGGAGGSGGFSNSGNGGAGGAGGDAGLLVGSGGAGGAGASATGAATGGDGGAGGKSGAFGLGGDGGA GGATGLSGAFHIGGKGGVGGSAVLIGNGGNGGNGGNSGNAGKSGGAPGPSGAGGAGGLLLGENGLNGLM
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0768 | PE_PGRS10 | - | 100% (909) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0286c | PE_PGRS3 | 0.0 | 72.80% (919) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1789c | wag22b | 0.0 | 68.16% (851) | hypothetical protein Mb1789c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-168 | 46.70% (803) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0747 | PE_PGRS10 | 0.0 | 82.87% (759) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 7e-11 | 38.37% (86) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-50 | 32.57% (525) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4399 | - | 0.0 | 57.63% (963) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 5e-24 | 45.51% (167) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-142 | 38.43% (1054) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-40 | 37.28% (346) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 54.00% (950) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-167 | 45.84% (853) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0768|M.bovis_AF2122/97 --------------------------------------------------
Rv0747|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4399|M.marinum_M --------------------------------------------------
MUL_3062|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0768|M.bovis_AF2122/97 --------------------MSWVMVSPELVVAAAADLAGIG--------
Rv0747|M.tuberculosis_H37Rv --------------------MSWVMVSPELVVAAAADLAGIG--------
MMAR_4399|M.marinum_M --------------------MSYVIAVPDLVAGAASELAGVG--------
MUL_3062|M.ulcerans_Agy99 --------------------MAFVLAVPDMVAEAAADLAGVG--------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------MSIIDFILNLFRDPVEAASYVADPEA-------
MAV_4827|M.avium_104 --------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEED----
Mb0768|M.bovis_AF2122/97 -------------------------------------SAISSANAAAAVN
Rv0747|M.tuberculosis_H37Rv -------------------------------------SAISSANAAAAVN
MMAR_4399|M.marinum_M -------------------------------------STLSTATTAAAAQ
MUL_3062|M.ulcerans_Agy99 -------------------------------------SVIDAANTAAAGS
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------ALANAGLSAVSAA
MAV_4827|M.avium_104 -----------------------------------AIDVTGADDAATASA
Mb0768|M.bovis_AF2122/97 TTG--------------------------------------LLTAGADEV
Rv0747|M.tuberculosis_H37Rv TTG--------------------------------------LLTAGADEV
MMAR_4399|M.marinum_M TTG--------------------------------------VLAAAGDEV
MUL_3062|M.ulcerans_Agy99 TTG--------------------------------------IVAAAEDEV
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 QVG-------------------------------------AVMPVVAESV
MAV_4827|M.avium_104 PDR--------------------------------------VISAILGTR
Mb0768|M.bovis_AF2122/97 S---------------------TAIAALFGAQGQAYQAASAQAAAFYAQF
Rv0747|M.tuberculosis_H37Rv S---------------------TAIAALFGAQGQAYQAASAQAAAFYAQF
MMAR_4399|M.marinum_M S---------------------AAIAAVFSAHGQSYQTLSAQAETFHAQF
MUL_3062|M.ulcerans_Agy99 S---------------------AAIAALFSGHGQAYQQISTRVAEFHAQF
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ASN-------------------YGYQSQWVNTGNPIHDLSGNLQNYYAAQ
MAV_4827|M.avium_104 EG-------------------AADAGLQLSSIGVTWTDQLEAAALRDALA
Mb0768|M.bovis_AF2122/97 VQALSAGGGAYAAAEAAAVS-------PLLAPINAQFVAATGRPLIGNGA
Rv0747|M.tuberculosis_H37Rv VQALSAGGGAYAAAEAAAVS-------PLLAPINAQFVAATGRPLIGNGA
MMAR_4399|M.marinum_M VQALSAGASAYTQAEAASAS----PLAGLLAAINAPVQSLTGRPLIGNGA
MUL_3062|M.ulcerans_Agy99 ERVFAAGVQAYSGAEAANASFLQDPLQTALNATNKPVQDLTGRPLVGNGA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWN----SDVVGMDGGNGGNGGLFGGNGGNGGN
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWN----SEIAGVSGGNGGNAGLFGGNGGNGGN
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYD----GSAAGLAGGNGGNAGLFG-NGGNGGV
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLS---HNDTDFASHNPIASGNQVMSPSGNVD
MAV_4827|M.avium_104 ARRIDNVMLVSAFLAAAALAQN-----VGGAMGYERTAVLLVEPDTATLA
Mb0768|M.bovis_AF2122/97 NGAPGTGANGGPGG--WLIGNGGAGGSGAPGAGAGGNGGAGGLFGSGGAG
Rv0747|M.tuberculosis_H37Rv NGAPGTGANGGPGG--WLIGNGGAGGSGAPGAGAGGNGGAGGLFGSGGAG
MMAR_4399|M.marinum_M NGTPGTGADGAPGG--WLLGDGGAGGSGAPGL-NGGAGGAAGLLGSGGAG
MUL_3062|M.ulcerans_Agy99 NGVPGTGANGAAGG--WLLGNGGAGGSGAAGQ-AGGDGGAAGLIGAGGAG
Mflv_5091|M.gilvum_PYR-GCK GLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGAT
Mvan_1264|M.vanbaalenii_PYR-1 GLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGAT
MSMEG_0868|M.smegmatis_MC2_155 GWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTG
TH_3810|M.thermoresistible__bu --VDGDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVN
MAV_4827|M.avium_104 VVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVG
Mb0768|M.bovis_AF2122/97 GAGGNAFGAGEVGGAGGAGGNA--MLFGAGGAGGAG--------------
Rv0747|M.tuberculosis_H37Rv GAS------TDV----------------AGGAGGAG--------------
MMAR_4399|M.marinum_M GAGGSS---TSTNGGAGGAGGAGGWLSGNAGVGGAGGASTVAN-------
MUL_3062|M.ulcerans_Agy99 GAGGNSPLRNTANGGNGGTGGAGGLLFGPGGVGGAGGASFLT--------
Mflv_5091|M.gilvum_PYR-GCK GATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-----------
Mvan_1264|M.vanbaalenii_PYR-1 GATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-----------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAG
TH_3810|M.thermoresistible__bu GGTGIIS--------------------LLSLAGNGGNGG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GDVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKS------
MAV_4827|M.avium_104 SGVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAANAP--------
Mb0768|M.bovis_AF2122/97 ----GAGGNAGMLFGAAGVGGVGGFSNGG-ATGGAGGAGGAGGLFTTGGV
Rv0747|M.tuberculosis_H37Rv ----GAGGNAGMLFGAAGVGGVGGFSNGG-ATGGAGGAGGAG--------
MMAR_4399|M.marinum_M -GGAGGAGGAGGLLGGGGLGGAGGASTSATASGGAGGQGGAAGLLSG---
MUL_3062|M.ulcerans_Agy99 -GGTGGDGGAGGLFGAGGLGGVGGSGN----VGGNGGAGGAGGLLAG---
Mflv_5091|M.gilvum_PYR-GCK ---AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG------------
Mvan_1264|M.vanbaalenii_PYR-1 ---AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG------------
MSMEG_0868|M.smegmatis_MC2_155 PNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGT
TH_3810|M.thermoresistible__bu ----NGYRTTDNNALDGGHGG-----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----VTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIG--------
MAV_4827|M.avium_104 --LFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDD--------
Mb0768|M.bovis_AF2122/97 GGAGGAGGDGGDGGAGGLFGAGGTGGAGGFGTAVLAGTGGAGGPGGAGGL
Rv0747|M.tuberculosis_H37Rv ------------------------------------------------GL
MMAR_4399|M.marinum_M ----FVGADGGHGGAGGHGAAGGDGGAGG----------------DGGPL
MUL_3062|M.ulcerans_Agy99 ----LVGAGGGDGGSGGLGAAGGDGGNGG----------------RAGLF
Mflv_5091|M.gilvum_PYR-GCK ----AVGAAGAAG------TVGTAGATGGTG---------------TGAN
Mvan_1264|M.vanbaalenii_PYR-1 ----AIGTAGVAG------AAGTAGATGGTG---------------VGGN
MSMEG_0868|M.smegmatis_MC2_155 VDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGD
TH_3810|M.thermoresistible__bu ----------------------------------------------NGGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------------SHNQ
MAV_4827|M.avium_104 ----------------------------------------------ELAY
Mb0768|M.bovis_AF2122/97 FGAGGEGGSGGSGNLT-------------------GGAGGAGGNAGTLAT
Rv0747|M.tuberculosis_H37Rv FGAGRERGSGGSGNLT-------------------GGAGGAGGNAGTLAT
MMAR_4399|M.marinum_M AGAGGSGGTGGSGNAG-------------------GGAGGAGGNAG-LLF
MUL_3062|M.ulcerans_Agy99 GGAGGAGGMGATGGHS-------------------GGDGGAGGDAG-LLF
Mflv_5091|M.gilvum_PYR-GCK GGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGV
Mvan_1264|M.vanbaalenii_PYR-1 GGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGI
MSMEG_0868|M.smegmatis_MC2_155 GGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGM
TH_3810|M.thermoresistible__bu VGFFSLFNLGG--------------------AGGWGGSGVDG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ANIGTSTSAGGSAAVG----------------GNAGLAGNAGLAGNAGLA
MAV_4827|M.avium_104 SAVGEEDAESPTVVIEKLFLP--------------EDSEPRRRPVLLVGS
Mb0768|M.bovis_AF2122/97 GDGGAGGTGGASRSGGFGGAGGAGGDAGMFFGSGGSGGAGGAGGSGGFGL
Rv0747|M.tuberculosis_H37Rv GDGGAGGTGGASRSGGFGGAGGAGGDAGMFFGSGGSGGAG----------
MMAR_4399|M.marinum_M GDGGVGGTGGTSGQG-VGGIGGDGGSAGLLFSNGGAGGAGGAGTA--LIS
MUL_3062|M.ulcerans_Agy99 GTGGAGGAGGHAFDG-DGGAGGAGGNAGLMFSSGGSGGVGGAG------S
Mflv_5091|M.gilvum_PYR-GCK GGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-------
Mvan_1264|M.vanbaalenii_PYR-1 GGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-------
MSMEG_0868|M.smegmatis_MC2_155 GEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKA
TH_3810|M.thermoresistible__bu -------------VDVVGGNP-----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG-------
MAV_4827|M.avium_104 GLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAP-----
Mb0768|M.bovis_AF2122/97 PSGGKGGAGGDAGMLFGSGGSGGAGGISR--------SVGDGAAGGAGGA
Rv0747|M.tuberculosis_H37Rv -------------------------GISK--------SVGDSAAGGAGGA
MMAR_4399|M.marinum_M GNGGAGGNGGNGGWLFSNGGVGGAGGAGAPAMPSLGISAGSGGVGGAGGT
MUL_3062|M.ulcerans_Agy99 IDGGAGGAGGDAGWLGG-GGAGGAGGFGT-------ISD--GGAGGRGGG
Mflv_5091|M.gilvum_PYR-GCK ------LQGGKGGDGGAGGKGGDADSMGS------------------AGA
Mvan_1264|M.vanbaalenii_PYR-1 ------LQGGQGGDGGTGGTGGDATSMGE------------------AGA
MSMEG_0868|M.smegmatis_MC2_155 SGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASA
TH_3810|M.thermoresistible__bu -------------DGGTPG------------------------------A
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------------------A
Mb0768|M.bovis_AF2122/97 PG-LIGNGGNGGNGGAS------------TGGGDGGPGGAGGTGVLIG--
Rv0747|M.tuberculosis_H37Rv PG-LIGNGGNGGNGGAS------------TGGGDGGPGGAGGTGVLIG--
MMAR_4399|M.marinum_M GGLLLGNGGAGGAGGTSG-----------NGGGTGGAGGAAGSGVLIG--
MUL_3062|M.ulcerans_Agy99 GGQLLGNGGAGGAGGQGG-----------NDGGAGGLG---GNGVLIG--
Mflv_5091|M.gilvum_PYR-GCK TGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-------
Mvan_1264|M.vanbaalenii_PYR-1 TGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-------
MSMEG_0868|M.smegmatis_MC2_155 NGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYD
TH_3810|M.thermoresistible__bu HGESHTPGVYTDRQ------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAGLAG--------------------------------
MAV_4827|M.avium_104 PPPVQASAPQPKISVPEP--------------------------------
Mb0768|M.bovis_AF2122/97 -----------------NGG---SGGTGATLGKAGIGGTGGVLLGLDG--
Rv0747|M.tuberculosis_H37Rv -----------------NGGNGGSGGTGATLGKAGIGGTGGVLLGLDG--
MMAR_4399|M.marinum_M -----------------NGGNGGIGGAGPTPGGNGIGGTSGLLLGLDG--
MUL_3062|M.ulcerans_Agy99 -----------------NGGNGGVGGVGETPGGDGGGGISGLLLGADG--
Mflv_5091|M.gilvum_PYR-GCK ---------------GGTGGAGGAGGTGG-TGGAGGTGG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------GGTGGNGGNGGTGG-TGGNGGTGG-----------
MSMEG_0868|M.smegmatis_MC2_155 PNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQH
TH_3810|M.thermoresistible__bu -------------------GEDGEDGTGTGIGGRGGNGG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------NAGLAGNAGLAGNAGLAGNAG---------
MAV_4827|M.avium_104 --------------------VAAPKPLSPPVAAPLPAAP-----------
Mb0768|M.bovis_AF2122/97 ---FTAPASTSPLHTLQQDVINMVNDPFQTLTGRPLIGNGANGTPGTGAD
Rv0747|M.tuberculosis_H37Rv ---FTAPASTSPLHTLQQDVINMVNDPFQTLTGRPLIGNGANGTPGTGAD
MMAR_4399|M.marinum_M ---FNAPTSTSPIHTLQQQALNAINAPIQAATGRPLIGNGTPGDAGSGTD
MUL_3062|M.ulcerans_Agy99 ---FNAPAGSSPVHALQQQALAAINAPVQELTGRPLIGNGLPGSAGSGAA
Mflv_5091|M.gilvum_PYR-GCK ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 STGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGD
TH_3810|M.thermoresistible__bu -----SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGN
MLBr_01183|M.leprae_Br4923 ---------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIA
MAB_4284c|M.abscessus_ATCC_199 ------LAGNAGLAGNAGLAGNAGLAGNAGLAGN-AAVAGNAAVAGNAAV
MAV_4827|M.avium_104 ------PPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVS
Mb0768|M.bovis_AF2122/97 GGAGG--WLFGNGGNGGQGTIGGVNGGAGGAGGAGGI--------LFGTG
Rv0747|M.tuberculosis_H37Rv GGAGG--WLFGNGGNGGQGTIGGVNGGAGGAGGAGGI--------LFGTG
MMAR_4399|M.marinum_M GTPGG--WLLGDGGAG--GSGGT--GLDGGDGGAAG---------LMGTG
MUL_3062|M.ulcerans_Agy99 GAPGG--WLLGDGGAG--GSAAATPGAAGGAGGAAG---------LVGAG
Mflv_5091|M.gilvum_PYR-GCK GGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNG
TH_3810|M.thermoresistible__bu GGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADG
MLBr_01183|M.leprae_Br4923 PPAADDVSILLAHFFS-------------GHGRQ-----------YQAHA
MAB_4284c|M.abscessus_ATCC_199 AGNAAVGGVLNTGVSG-------AIGGSSHVGGAIN----------ESLG
MAV_4827|M.avium_104 PPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVP---------QSPPQ
*
Mb0768|M.bovis_AF2122/97 GTGGSG-------GPGATGLGGIGGAGG-AALLFGSGGAGGSGGAGAVGG
Rv0747|M.tuberculosis_H37Rv GTGGSG-------GPGATGLGGIGGAGG-AALLFGSGGAGGSGGAGAVGG
MMAR_4399|M.marinum_M GTGGAGGW--GGTDEITGGTGGAGGTGGGGGWLSGSGGIGGGGGAGGYGG
MUL_3062|M.ulcerans_Agy99 GAGGAG----ANTGISNPGFGGAGGAGG--------AGAGAGGGVG----
Mflv_5091|M.gilvum_PYR-GCK GTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG------
MSMEG_0868|M.smegmatis_MC2_155 GNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRA
TH_3810|M.thermoresistible__bu GNGGDG---------------GNGGSAG----------------------
MLBr_01183|M.leprae_Br4923 SQGATN--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSGSVG---------------GSTAVGG----------------------
MAV_4827|M.avium_104 HQTPPG--------------EGTPPKPD----------------------
.
Mb0768|M.bovis_AF2122/97 ----------NGGAGGNAGALLGAAGAGG---------------------
Rv0747|M.tuberculosis_H37Rv ----------NGGAGGNAGALLGAAGAGG---------------------
MMAR_4399|M.marinum_M AIIPGNGGAGGSAGAGGAGGLFGGGGTGG---------------------
MUL_3062|M.ulcerans_Agy99 -------------EAGGAGGLLGAGGTGG---------------------
Mflv_5091|M.gilvum_PYR-GCK -----------TGGTGGQGG-LGGGGGTG---------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------TGGTGGQGG-LGGVGGTG---------------------
MSMEG_0868|M.smegmatis_MC2_155 TVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTA
TH_3810|M.thermoresistible__bu -----------RGGTGGLRGVFGINGGNG---------------------
MLBr_01183|M.leprae_Br4923 -------------HQDLIQSLLTSSSAYA---------------------
MAB_4284c|M.abscessus_ATCC_199 ------------GAHTGVGGGVSTGVGVG---------------------
MAV_4827|M.avium_104 ------------GPGNYGGGHVPTPGAGG---------------------
. . .
Mb0768|M.bovis_AF2122/97 ---AGGAG-----------AVGGNGGAGGNGGLFANG-----GAGGPGGF
Rv0747|M.tuberculosis_H37Rv ---AGGAG-----------AVGGNGGAGGNGGLFANG-----GAGGPGGF
MMAR_4399|M.marinum_M ---AGGTGGPAGLGVFVGVPTFGDGGGGGAGGAGGAG-----GLLS-GLV
MUL_3062|M.ulcerans_Agy99 ---GGGVA-----------PSLVDGGTGGAGGAGGAG-----GLFG-GIF
Mflv_5091|M.gilvum_PYR-GCK --GQGGTG-----------GTGGQGGTGGTGGTGGTG--------GTGGA
Mvan_1264|M.vanbaalenii_PYR-1 --GTGGTG-----------GTGGQGGTGGTGGTGGTG--------GTGGA
MSMEG_0868|M.smegmatis_MC2_155 TDGHGGSG-----------INGGHGGNGGQGTIEANGPSAVASGIGAGGN
TH_3810|M.thermoresistible__bu ---RAGLG-----------GRGXXXXGGGVGAAVRSG-------------
MLBr_01183|M.leprae_Br4923 -----G------------------TETANHDSL-----------------
MAB_4284c|M.abscessus_ATCC_199 --SHVGGG-----------ISESLGGSGSVGGSTAVG-------------
MAV_4827|M.avium_104 ---SGGSG-------------GGHVPTPGAGGSGGSG-------------
* . .
Mb0768|M.bovis_AF2122/97 GSPAGAGGIGGAGGN--GGLFGAGGTGGAGGGSTLAGGAGGAGGNGGLFG
Rv0747|M.tuberculosis_H37Rv GSPAGAGGIGGAGGN--GGLFGAGGTGGAGGGSTLAGGAGGAGGNGGLFG
MMAR_4399|M.marinum_M GAGGGDGGAGGQGGIGFGGSGGSGGGGGVGGNAGLLGGPGGAGGSGGAAG
MUL_3062|M.ulcerans_Agy99 GAGGGDGGAGGFT----GGIDGAGGVGGAGGNTGLLGGPGGSGGSGGD-G
Mflv_5091|M.gilvum_PYR-GCK GGDGGLGGLGGFGGS--GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGK
Mvan_1264|M.vanbaalenii_PYR-1 GGDGGLGGLGGFGGV--GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGK
MSMEG_0868|M.smegmatis_MC2_155 GGDGIDGGLGGNGGD--GVVNTTANAANPGSATGTATGGDGGKATGTASQ
TH_3810|M.thermoresistible__bu --NGVFSGGGGTPSA--GFGVPTTIQFPAGSCTSRAVSREG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --GGAHTGVGGGVST--GVGVGSHVGGGISESLGGSGSVGGSTAVGGGAH
MAV_4827|M.avium_104 ---GGHVPTPGTGGP--GGTGGSGGGHVPTPGAGTPGGSGG---------
Mb0768|M.bovis_AF2122/97 AGGTGGAGSHSTAAGVSG--GAGGAGGDAGLLS-LGASGGAGGSGG----
Rv0747|M.tuberculosis_H37Rv AGGTGGAGSHSTAAGVSG--GAGGAGGDAGLLS-LGASGGAGGSGG----
MMAR_4399|M.marinum_M PALFG--------IGVDGTAGVGGAGGNAGLLFGSGGAGGDGGFG-----
MUL_3062|M.ulcerans_Agy99 IAKLG--------FNVDG--GAGGAGVNGGFLFGSGGTGGFGGVGGV---
Mflv_5091|M.gilvum_PYR-GCK GGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQ
Mvan_1264|M.vanbaalenii_PYR-1 GGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQ
MSMEG_0868|M.smegmatis_MC2_155 GGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAA
TH_3810|M.thermoresistible__bu ---------------IMPSSRAASARAG----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TGVGG----------GVNTGVGVGSHVGGGISESLGGSGSVG--------
MAV_4827|M.avium_104 --------------GHLPFPGAGSTPGGSG--------------------
Mb0768|M.bovis_AF2122/97 SSLTAAGVVGGIGGAGGLLFGSGGAGGSGGFSNSGNGGAGGAGGDAGLLV
Rv0747|M.tuberculosis_H37Rv SSLTAAGVVGGIGGAGGLLFGSGGAGGSGGFSNSGNGGAGGAGGDAGLLV
MMAR_4399|M.marinum_M ---PGAGGTGGRGGNAGLLFSSAGAGGFGGYGTTG-GGTGGAGGDAG-WL
MUL_3062|M.ulcerans_Agy99 GTSTGIGGAGGRGGNAGLLFSDAGVGGFGGFG--------GTGGNAG-WL
Mflv_5091|M.gilvum_PYR-GCK GATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGT
Mvan_1264|M.vanbaalenii_PYR-1 GATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGT
MSMEG_0868|M.smegmatis_MC2_155 GTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGH
TH_3810|M.thermoresistible__bu -----AACASSTSRSRRSFCCSRA--------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------GSTAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTSAINESM
MAV_4827|M.avium_104 ---------GGHLPTPGAGTPGGGLGGFG---------------------
Mb0768|M.bovis_AF2122/97 GSGGAGGAGASATGAATGGDGGAGGKSG-AFGLGGDGGAGGATGLSGAFH
Rv0747|M.tuberculosis_H37Rv GSGGAGGAGASATGAATGGDGGAGGKSG-AFGLGGDGGAGGATGLSGAFH
MMAR_4399|M.marinum_M GCGGAGGAGGITIGG-TGGTGGAGGTGGQLLGAGGAGGAGGQTDPLG-GS
MUL_3062|M.ulcerans_Agy99 GSGGSGGAGGGSNG--DGGAGGTGGSGGQIVGDGGAGGAGGQGDLLAAGG
Mflv_5091|M.gilvum_PYR-GCK NGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-
Mvan_1264|M.vanbaalenii_PYR-1 NGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-
MSMEG_0868|M.smegmatis_MC2_155 GGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPG
MAV_4827|M.avium_104 -----GGHAPAPGGGLGGGGGHAPAPGG------GLGGFGGGHSGGGLGG
Mb0768|M.bovis_AF2122/97 IGGKGG---------------VGGSAVLIGNGGNGGNGGNSGNAGK-SGG
Rv0747|M.tuberculosis_H37Rv IGGKGG---------------VGGSAVLIGNGGNGGNGGNSGNAGK-SGG
MMAR_4399|M.marinum_M TGGSGG---------------VGGNAVLIGTGGNGGNGG--------AGT
MUL_3062|M.ulcerans_Agy99 SGGDGG---------------QGGDAVLIGTGGNGGNGA--------SGV
Mflv_5091|M.gilvum_PYR-GCK INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE--------GG
Mvan_1264|M.vanbaalenii_PYR-1 INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE--------GG
MSMEG_0868|M.smegmatis_MC2_155 ASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AEHH----------------------------------------------
MAV_4827|M.avium_104 LGGGHK--------------------------------------------
Mb0768|M.bovis_AF2122/97 APGPSGAGGAGGLLLGENGLNGLM--------------------
Rv0747|M.tuberculosis_H37Rv APGPSGAGGAGGLLLGENGLNGLM--------------------
MMAR_4399|M.marinum_M AKGTPGTGGTGG-LIGVDGLSGAS--------------------
MUL_3062|M.ulcerans_Agy99 LAGIGGDGGSRGLLLGEDGVNGEAAPPMTHIVLLGGDFPAAAS-
Mflv_5091|M.gilvum_PYR-GCK AGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 AGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 AGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu --------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------