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RRVLDAAWEPTVPALMQLVAATAAPRLRSAFAAAGLDGIRPAQAIGLVPLAGGGLHASDLADRLGVSRQA VAQAVAALERHGYVLRAPDPADARARIIELTPRGRQALRVMRANALDAQRRWQKILGPQRLGELRETLQL LLDAESGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4886 | - | - | 100% (149) | hypothetical protein MUL_4886 |
| M. ulcerans Agy99 | MUL_0952 | - | 5e-11 | 34.38% (96) | putative regulatory protein |
| M. ulcerans Agy99 | MUL_0657 | - | 8e-06 | 35.00% (120) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0043c | - | 1e-05 | 34.19% (117) | MarR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2302 | - | 1e-15 | 33.33% (132) | MarR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0042c | - | 1e-05 | 34.19% (117) | MarR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02696 | - | 5e-05 | 31.58% (95) | putative MarR-family regulatory protein |
| M. abscessus ATCC 19977 | MAB_0157 | - | 4e-07 | 36.90% (84) | putative transcriptional regulator MarR |
| M. marinum M | MMAR_0228 | - | 4e-78 | 98.66% (149) | hypothetical protein MMAR_0228 |
| M. avium 104 | MAV_5249 | - | 2e-54 | 78.36% (134) | transcriptional regulator, MarR family protein |
| M. smegmatis MC2 155 | MSMEG_0469 | - | 9e-09 | 34.69% (98) | transcriptional regulatory protein PadR- |
| M. thermoresistible (build 8) | TH_0263 | - | 2e-08 | 31.91% (94) | transcriptional regulator, MarR family protein |
| M. vanbaalenii PYR-1 | Mvan_4344 | - | 1e-17 | 35.38% (130) | MarR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4886|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0228|M.marinum_M --------------------------------------------------
MAV_5249|M.avium_104 --------------------------------------------------
Mflv_2302|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4344|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0043c|M.bovis_AF2122/97 -----MSVVRSIG-KKMQRISGPNALAVKG--------------------
Rv0042c|M.tuberculosis_H37Rv -----MSVVRSIG-KKMQRISGPNALAVKG--------------------
MLBr_02696|M.leprae_Br4923 --MFSYITTKSWNPGNQSRYSRPRRLSAYNGLYPKYFDVLDFTNDDPLHP
MAB_0157|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0469|M.smegmatis_MC2_155 MSVTSVLRRFNRTYTQRIGVLDESYLGTGRPLNVSRVLFEIGGLGAVTIR
TH_0263|M.thermoresistible__bu --------------------------------------------------
MUL_4886|M.ulcerans_Agy99 -----------------------MRRVLDAAWEPTVPALMQLVA--ATAA
MMAR_0228|M.marinum_M -----------------------MRRVLDAAWEPTVPALMQLVA--ATAA
MAV_5249|M.avium_104 -----------------------------------MPALVNLVA--AAGA
Mflv_2302|M.gilvum_PYR-GCK -----------------------------MDEIPATAVLMFMAH--RDVE
Mvan_4344|M.vanbaalenii_PYR-1 -----------------------------MDAQPGTAVLMYIAH--REVE
Mb0043c|M.bovis_AF2122/97 -----RPTQVYGHT------HVRLDCRFMADSEFTAPEVTQLAEGLHRAL
Rv0042c|M.tuberculosis_H37Rv -----RPTQVYGHT------HVRLDCRFMADSEFTAPEVTQLAEGLHRAL
MLBr_02696|M.leprae_Br4923 APPHLRPPLQLAHTRSLNARHIALNCRLMADSEFTAHEVTELADGLHRAL
MAB_0157|M.abscessus_ATCC_1997 ---------------------------MSTTDGLTADVLTVIAR-----L
MSMEG_0469|M.smegmatis_MC2_155 DLRDRLGLDSGYVTRILTRLENEGLVRVVPDPADGRRRIVELTDAGREAV
TH_0263|M.thermoresistible__bu -------------------------VADDLAMEFGDNLLWHLKQAWYFSL
: :
MUL_4886|M.ulcerans_Agy99 PRLRSAFAAAGLDGIRP-----------AQAIGLVPLAGGGLHASDLADR
MMAR_0228|M.marinum_M PRLRSAFAEAGLDGIRP-----------AQAIGLVPLAGGGLHASDLADR
MAV_5249|M.avium_104 PRLRAAFAEAALDGIRP-----------AQSLALVPLAAGGLHASDLADR
Mflv_2302|M.gilvum_PYR-GCK TRVMAALGQAGHDDITM-----------AQSRLMQRLDPGGMRLTELAEQ
Mvan_4344|M.vanbaalenii_PYR-1 SRVMAALARSGVGDVTV-----------AQSRLLQRLDPGGMRLTDLAEQ
Mb0043c|M.bovis_AF2122/97 SKLISMLRRGDPNGAAAGDLT-----LAQLSILVTLLDQGPIRMTDLAAH
Rv0042c|M.tuberculosis_H37Rv SKLISMLRRGDPNGAAAGDLT-----LAQLSILVTLLDQGPIRMTDLAAH
MLBr_02696|M.leprae_Br4923 SKLFSILRRRTPNGAVSGELT-----LAQLSILVTLLDQGPIRMTDLAAH
MAB_0157|M.abscessus_ATCC_1997 NRWVSSYADLPVPTGQA-------------RLLALVGEMEDARISDLAQA
MSMEG_0469|M.smegmatis_MC2_155 NELEDRSESRAADLVAPLTARQRERLADALATAELLVRAATVRLVEVDQD
TH_0263|M.thermoresistible__bu TAVNDAVSKHGVSTAQIG-------------VLRQLSNEPGLSGAELARR
::
MUL_4886|M.ulcerans_Agy99 LGVSRQAVAQAVAALER---HGYVLRAPDPADARARIIELTPRGRQALR-
MMAR_0228|M.marinum_M LGVSRQAVAQAVTALER---HGYVLRAPDPADARARIIELTPRGRQALR-
MAV_5249|M.avium_104 LRVSRQAVAQAVAALER---HGYVTRTPDPADARARMIELTPRGRQALQ-
Mflv_2302|M.gilvum_PYR-GCK ARVTKQTAGALIDQLER---SGYVTRLPDPTDARARLVTLSDRGVEMCR-
Mvan_4344|M.vanbaalenii_PYR-1 ARVTKQTAGALVDQLER---AGYVTRQPDPSDARARLVTLTDKGAEMCR-
Mb0043c|M.bovis_AF2122/97 ERVRTPTTTVAIRRLEK---IGLVKRSRDPSDLRAVLVDITPQGRAVHG-
Rv0042c|M.tuberculosis_H37Rv ERVRTPTTTVAIRRLEK---IGLVKRSRDPSDLRAVLVDITPQGRAVHG-
MLBr_02696|M.leprae_Br4923 ERVRTPTTTVAIRRLEK---IGLVKRSRDLSDLRAVLVDITPRGRTVHG-
MAB_0157|M.abscessus_ATCC_1997 DHCSQPTMTVQLKRLQD---VGYVERRVDPADKRAQRIKLTSKGREALV-
MSMEG_0469|M.smegmatis_MC2_155 SDVARTALTHYYDELNRRFPQGFDPGAPSGPEHGAHYIAAISDGQPVGFG
TH_0263|M.thermoresistible__bu LLITPQGVQLALKSLEQ---RGLIERRPDPQHARILKVYLTREGRSVAK-
*: * . . : *
MUL_4886|M.ulcerans_Agy99 ------------VMRANALDAQRRWQ---------------------KIL
MMAR_0228|M.marinum_M ------------VMRANALDAQRRWQ---------------------KIL
MAV_5249|M.avium_104 ------------VMRANAIAMEKRWR---------------------KVL
Mflv_2302|M.gilvum_PYR-GCK ------------RAGAEVGRVEAEWR---------------------ERL
Mvan_4344|M.vanbaalenii_PYR-1 ------------RAGAEVARVEQEWR---------------------QHL
Mb0043c|M.bovis_AF2122/97 ------------ESLANRRAALAALL---------------------SQL
Rv0042c|M.tuberculosis_H37Rv ------------ESLANRRAALAALL---------------------SQL
MLBr_02696|M.leprae_Br4923 ------------ESLANRRAALTTML---------------------SQL
MAB_0157|M.abscessus_ATCC_1997 ------------AMRAQRQGVLDPWL---------------------STL
MSMEG_0469|M.smegmatis_MC2_155 GIRPLESGDDGPVAEVKRMWVDDRWRGAGLGSRILRHLETLAAEHGFARV
TH_0263|M.thermoresistible__bu ------------AVVGDAIAAHEAVFG---------------------VL
. :
MUL_4886|M.ulcerans_Agy99 GPQRLGELRETLQLLLDAESGA------------------
MMAR_0228|M.marinum_M GPQRLGELRETLQLLLDAESGA------------------
MAV_5249|M.avium_104 GERRLTELRETLTMLLAAEREPGG----------------
Mflv_2302|M.gilvum_PYR-GCK GDTAFDAMRDALVTLASE----------------------
Mvan_4344|M.vanbaalenii_PYR-1 GDDAYGALRAALLSLREITDPYL-----------------
Mb0043c|M.bovis_AF2122/97 PRSDLETLRKALAPLERLASGEPASGPASNSPARKRA---
Rv0042c|M.tuberculosis_H37Rv PRSDLETLRKALAPLERLASGEPASGPASNSPARKRA---
MLBr_02696|M.leprae_Br4923 PTSDLNILKNALAPLQRLASGEPVSSPAGDSPACKQA---
MAB_0157|M.abscessus_ATCC_1997 PAEEQRTLAEAAAILERLTRRMAAQSG-------------
MSMEG_0469|M.smegmatis_MC2_155 RLDTNGNLGEAIALYERTGYAQIDRYNDNPYAQFFFEKRL
TH_0263|M.thermoresistible__bu TPEEQRTLRDLLARVVEKGTGHTLADDHITD---------
: