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M. tuberculosis H37Rv Rv0042c (-)

annotation: POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY MARR-FAMILY)
coordinates: 46581 - 47207
length: 208

SVVRSIGKKMQRISGPNALAVKGRPTQVYGHTHVRLDCRFMADSEFTAPEVTQLAEGLHRALSKLISMLR
RGDPNGAAAGDLTLAQLSILVTLLDQGPIRMTDLAAHERVRTPTTTVAIRRLEKIGLVKRSRDPSDLRAV
LVDITPQGRAVHGESLANRRAALAALLSQLPRSDLETLRKALAPLERLASGEPASGPASNSPARKRA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0042c--100% (208)POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY MARR-FAMILY)
M. tuberculosis H37RvRv2327-2e-1542.99% (107) hypothetical protein Rv2327
M. tuberculosis H37RvRv0880-6e-1234.04% (141) MarR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0043c-1e-113100.00% (208) MarR family transcriptional regulator
M. gilvum PYR-GCKMflv_0856-1e-4567.13% (143) MarR family transcriptional regulator
M. leprae Br4923MLBr_02696-3e-7677.37% (190) putative MarR-family regulatory protein
M. abscessus ATCC 19977MAB_0157-5e-1236.89% (103) putative transcriptional regulator MarR
M. marinum MMMAR_0059-6e-7285.09% (161) transcriptional regulatory protein
M. avium 104MAV_0057-3e-7788.02% (167) transcriptional regulator, MarR family protein
M. smegmatis MC2 155MSMEG_6913-9e-5173.43% (143) putative transcriptional regulatory protein
M. thermoresistible (build 8)TH_0729-1e-1537.60% (125) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_0058-1e-7184.47% (161) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_6049-6e-4767.83% (143) MarR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0856|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_6049|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_6913|M.smegmatis_MC2_155      --------------------------------------------------
Rv0042c|M.tuberculosis_H37Rv        ----MSVVRSIGKKMQRISGPNALAVKG----------------------
Mb0043c|M.bovis_AF2122/97           ----MSVVRSIGKKMQRISGPNALAVKG----------------------
MAV_0057|M.avium_104                --------------------------------------------------
MMAR_0059|M.marinum_M               --------------------------------------------------
MUL_0058|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02696|M.leprae_Br4923          MFSYITTKSWNPGNQSRYSRPRRLSAYNGLYPKYFDVLDFTNDDPLHPAP
MAB_0157|M.abscessus_ATCC_1997      --------------------------------------------------
TH_0729|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0856|M.gilvum_PYR-GCK          --------------------------MVTTD---AQVSELAGELQRVLSK
Mvan_6049|M.vanbaalenii_PYR-1       --------------------------MVPTE---ARVSELASELQRVLSK
MSMEG_6913|M.smegmatis_MC2_155      --------------------------MAETE---PQVTELAGELQRVLSK
Rv0042c|M.tuberculosis_H37Rv        ---RPTQVYGHT------HVRLDCRFMADSEFTAPEVTQLAEGLHRALSK
Mb0043c|M.bovis_AF2122/97           ---RPTQVYGHT------HVRLDCRFMADSEFTAPEVTQLAEGLHRALSK
MAV_0057|M.avium_104                --------------------------MADSESNAAEVAELAEGLHRALSK
MMAR_0059|M.marinum_M               --------------------------MADSESTAPEVTELAEGLHRALSK
MUL_0058|M.ulcerans_Agy99           --------------------------MADSESTAPEVTELAEGLHRALSK
MLBr_02696|M.leprae_Br4923          PHLRPPLQLAHTRSLNARHIALNCRLMADSEFTAHEVTELADGLHRALSK
MAB_0157|M.abscessus_ATCC_1997      --------------------------MSTTDGLTADVLTVIARLNRWVSS
TH_0729|M.thermoresistible__bu      ---------------------MKPPAVDPSTSLGADLLWVVSRINRLATQ
                                                              :  :      :  :   ::*  :.

Mflv_0856|M.gilvum_PYR-GCK          LMSVMRHTG-RTPTSGDLTLAQLSILLTLIDQGPMRMTELAAHEKVRTPT
Mvan_6049|M.vanbaalenii_PYR-1       VLSVMRHTG-RTATSGDLTLAQLSILLTLFDQGPMRMTELAAHEKVRTPT
MSMEG_6913|M.smegmatis_MC2_155      VFSVLRRGDTHRGTAGDLTLAQLSILLTLLEGGPIRMTELAARERVRTPT
Rv0042c|M.tuberculosis_H37Rv        LISMLRRGDPNGAAAGDLTLAQLSILVTLLDQGPIRMTDLAAHERVRTPT
Mb0043c|M.bovis_AF2122/97           LISMLRRGDPNGAAAGDLTLAQLSILVTLLDQGPIRMTDLAAHERVRTPT
MAV_0057|M.avium_104                LFAMLRRGDPSGAAAGDLTLAQLSILVTLLDQGPIRMTDLAAHERVRTPT
MMAR_0059|M.marinum_M               LFSILRRGDPNGVVAGELTLAQLSILVTLLDRGPIRMTDLAAHERVRTPT
MUL_0058|M.ulcerans_Agy99           LFSILRRGDPNGVVAGELTLAQLSILVTLLDRGPIRMTDLAAHERVRTPT
MLBr_02696|M.leprae_Br4923          LFSILRRRTPNGAVSGELTLAQLSILVTLLDQGPIRMTDLAAHERVRTPT
MAB_0157|M.abscessus_ATCC_1997      YADLP------------VPTGQARLLALVGEMEDARISDLAQADHCSQPT
TH_0729|M.thermoresistible__bu      RIRLP------------LPVAQARLLSTIQDRGSARISDLAVLDHCSQPT
                                       :             :. .*  :*  : :    *:::**  ::   **

Mflv_0856|M.gilvum_PYR-GCK          TTVAIRRLEKLGLVKRDRDPSDLRAVLVDITPEGLAQHQEALAIRQAHLA
Mvan_6049|M.vanbaalenii_PYR-1       TTVAIRRLEKLGLVKRDRDPSDLRAVLVDITPEGLAQHREALASRQAHLA
MSMEG_6913|M.smegmatis_MC2_155      TTVAIRRLEKLGLVKRSRDPSDLRAVLVDVTPQGLVQHRESLAARRADLA
Rv0042c|M.tuberculosis_H37Rv        TTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRAVHGESLANRRAALA
Mb0043c|M.bovis_AF2122/97           TTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRAVHGESLANRRAALA
MAV_0057|M.avium_104                TTVAIRRLEKVGLVKRSRDPSDLRAVLVDITPRGRAVHGESLANRRAALA
MMAR_0059|M.marinum_M               TTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRSVHAESLANRHAALA
MUL_0058|M.ulcerans_Agy99           TTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRSVHAKSLANRHAALA
MLBr_02696|M.leprae_Br4923          TTVAIRRLEKIGLVKRSRDLSDLRAVLVDITPRGRTVHGESLANRRAALT
MAB_0157|M.abscessus_ATCC_1997      MTVQLKRLQDVGYVERRVDPADKRAQRIKLTSKGREALVAMRAQRQGVLD
TH_0729|M.thermoresistible__bu      MTTQVRRLEEAGLVSRTVDPDDGRAVRISITPEGVRTLAQVRADRAAAID
                                     *. ::**:. * *.*  *  * **  :.:*..*        * * . : 

Mflv_0856|M.gilvum_PYR-GCK          SLLGKLSCDELDALTKALAPLERIAE-----------------------
Mvan_6049|M.vanbaalenii_PYR-1       SLLSKLSDEELDALTKALAPLERIAE-----------------------
MSMEG_6913|M.smegmatis_MC2_155      ERLSKLSDEDLATLARALGPLERLAGQDEDKKNERETPKPAEQTS----
Rv0042c|M.tuberculosis_H37Rv        ALLSQLPRSDLETLRKALAPLERLASGEPASGPASNSPARKRA------
Mb0043c|M.bovis_AF2122/97           ALLSQLPRSDLETLRKALAPLERLASGEPASGPASNSPARKRA------
MAV_0057|M.avium_104                AMLSQLPASDLDTLMKALAPLERLASGDPTSGPAGVPPARKEA------
MMAR_0059|M.marinum_M               AMLDQLPHSDLETLMTALTPLERLACGEPANAPEDDAATPGRG------
MUL_0058|M.ulcerans_Agy99           AMLDQLPHSDLETLMTALTPLERLACGEPANAPEDDAATPGRG------
MLBr_02696|M.leprae_Br4923          TMLSQLPTSDLNILKNALAPLQRLASGEPVSSPAGDSPACKQA------
MAB_0157|M.abscessus_ATCC_1997      PWLSTLPAEEQRTLAEAAAILERLTRRMAAQSG----------------
TH_0729|M.thermoresistible__bu      PYIDRLSDTDRAVLADAVRVMRQLLADAADPAVLPADPPSRPHESTELR
                                      :. *.  :   *  *   :.::