For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SVVRSIGKKMQRISGPNALAVKGRPTQVYGHTHVRLDCRFMADSEFTAPEVTQLAEGLHRALSKLISMLR RGDPNGAAAGDLTLAQLSILVTLLDQGPIRMTDLAAHERVRTPTTTVAIRRLEKIGLVKRSRDPSDLRAV LVDITPQGRAVHGESLANRRAALAALLSQLPRSDLETLRKALAPLERLASGEPASGPASNSPARKRA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0042c | - | - | 100% (208) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY MARR-FAMILY) |
M. tuberculosis H37Rv | Rv2327 | - | 2e-15 | 42.99% (107) | hypothetical protein Rv2327 |
M. tuberculosis H37Rv | Rv0880 | - | 6e-12 | 34.04% (141) | MarR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0043c | - | 1e-113 | 100.00% (208) | MarR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_0856 | - | 1e-45 | 67.13% (143) | MarR family transcriptional regulator |
M. leprae Br4923 | MLBr_02696 | - | 3e-76 | 77.37% (190) | putative MarR-family regulatory protein |
M. abscessus ATCC 19977 | MAB_0157 | - | 5e-12 | 36.89% (103) | putative transcriptional regulator MarR |
M. marinum M | MMAR_0059 | - | 6e-72 | 85.09% (161) | transcriptional regulatory protein |
M. avium 104 | MAV_0057 | - | 3e-77 | 88.02% (167) | transcriptional regulator, MarR family protein |
M. smegmatis MC2 155 | MSMEG_6913 | - | 9e-51 | 73.43% (143) | putative transcriptional regulatory protein |
M. thermoresistible (build 8) | TH_0729 | - | 1e-15 | 37.60% (125) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_0058 | - | 1e-71 | 84.47% (161) | transcriptional regulatory protein |
M. vanbaalenii PYR-1 | Mvan_6049 | - | 6e-47 | 67.83% (143) | MarR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0856|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6049|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6913|M.smegmatis_MC2_155 -------------------------------------------------- Rv0042c|M.tuberculosis_H37Rv ----MSVVRSIGKKMQRISGPNALAVKG---------------------- Mb0043c|M.bovis_AF2122/97 ----MSVVRSIGKKMQRISGPNALAVKG---------------------- MAV_0057|M.avium_104 -------------------------------------------------- MMAR_0059|M.marinum_M -------------------------------------------------- MUL_0058|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02696|M.leprae_Br4923 MFSYITTKSWNPGNQSRYSRPRRLSAYNGLYPKYFDVLDFTNDDPLHPAP MAB_0157|M.abscessus_ATCC_1997 -------------------------------------------------- TH_0729|M.thermoresistible__bu -------------------------------------------------- Mflv_0856|M.gilvum_PYR-GCK --------------------------MVTTD---AQVSELAGELQRVLSK Mvan_6049|M.vanbaalenii_PYR-1 --------------------------MVPTE---ARVSELASELQRVLSK MSMEG_6913|M.smegmatis_MC2_155 --------------------------MAETE---PQVTELAGELQRVLSK Rv0042c|M.tuberculosis_H37Rv ---RPTQVYGHT------HVRLDCRFMADSEFTAPEVTQLAEGLHRALSK Mb0043c|M.bovis_AF2122/97 ---RPTQVYGHT------HVRLDCRFMADSEFTAPEVTQLAEGLHRALSK MAV_0057|M.avium_104 --------------------------MADSESNAAEVAELAEGLHRALSK MMAR_0059|M.marinum_M --------------------------MADSESTAPEVTELAEGLHRALSK MUL_0058|M.ulcerans_Agy99 --------------------------MADSESTAPEVTELAEGLHRALSK MLBr_02696|M.leprae_Br4923 PHLRPPLQLAHTRSLNARHIALNCRLMADSEFTAHEVTELADGLHRALSK MAB_0157|M.abscessus_ATCC_1997 --------------------------MSTTDGLTADVLTVIARLNRWVSS TH_0729|M.thermoresistible__bu ---------------------MKPPAVDPSTSLGADLLWVVSRINRLATQ : : : : ::* :. Mflv_0856|M.gilvum_PYR-GCK LMSVMRHTG-RTPTSGDLTLAQLSILLTLIDQGPMRMTELAAHEKVRTPT Mvan_6049|M.vanbaalenii_PYR-1 VLSVMRHTG-RTATSGDLTLAQLSILLTLFDQGPMRMTELAAHEKVRTPT MSMEG_6913|M.smegmatis_MC2_155 VFSVLRRGDTHRGTAGDLTLAQLSILLTLLEGGPIRMTELAARERVRTPT Rv0042c|M.tuberculosis_H37Rv LISMLRRGDPNGAAAGDLTLAQLSILVTLLDQGPIRMTDLAAHERVRTPT Mb0043c|M.bovis_AF2122/97 LISMLRRGDPNGAAAGDLTLAQLSILVTLLDQGPIRMTDLAAHERVRTPT MAV_0057|M.avium_104 LFAMLRRGDPSGAAAGDLTLAQLSILVTLLDQGPIRMTDLAAHERVRTPT MMAR_0059|M.marinum_M LFSILRRGDPNGVVAGELTLAQLSILVTLLDRGPIRMTDLAAHERVRTPT MUL_0058|M.ulcerans_Agy99 LFSILRRGDPNGVVAGELTLAQLSILVTLLDRGPIRMTDLAAHERVRTPT MLBr_02696|M.leprae_Br4923 LFSILRRRTPNGAVSGELTLAQLSILVTLLDQGPIRMTDLAAHERVRTPT MAB_0157|M.abscessus_ATCC_1997 YADLP------------VPTGQARLLALVGEMEDARISDLAQADHCSQPT TH_0729|M.thermoresistible__bu RIRLP------------LPVAQARLLSTIQDRGSARISDLAVLDHCSQPT : :. .* :* : : *:::** :: ** Mflv_0856|M.gilvum_PYR-GCK TTVAIRRLEKLGLVKRDRDPSDLRAVLVDITPEGLAQHQEALAIRQAHLA Mvan_6049|M.vanbaalenii_PYR-1 TTVAIRRLEKLGLVKRDRDPSDLRAVLVDITPEGLAQHREALASRQAHLA MSMEG_6913|M.smegmatis_MC2_155 TTVAIRRLEKLGLVKRSRDPSDLRAVLVDVTPQGLVQHRESLAARRADLA Rv0042c|M.tuberculosis_H37Rv TTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRAVHGESLANRRAALA Mb0043c|M.bovis_AF2122/97 TTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRAVHGESLANRRAALA MAV_0057|M.avium_104 TTVAIRRLEKVGLVKRSRDPSDLRAVLVDITPRGRAVHGESLANRRAALA MMAR_0059|M.marinum_M TTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRSVHAESLANRHAALA MUL_0058|M.ulcerans_Agy99 TTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRSVHAKSLANRHAALA MLBr_02696|M.leprae_Br4923 TTVAIRRLEKIGLVKRSRDLSDLRAVLVDITPRGRTVHGESLANRRAALT MAB_0157|M.abscessus_ATCC_1997 MTVQLKRLQDVGYVERRVDPADKRAQRIKLTSKGREALVAMRAQRQGVLD TH_0729|M.thermoresistible__bu MTTQVRRLEEAGLVSRTVDPDDGRAVRISITPEGVRTLAQVRADRAAAID *. ::**:. * *.* * * ** :.:*..* * * . : Mflv_0856|M.gilvum_PYR-GCK SLLGKLSCDELDALTKALAPLERIAE----------------------- Mvan_6049|M.vanbaalenii_PYR-1 SLLSKLSDEELDALTKALAPLERIAE----------------------- MSMEG_6913|M.smegmatis_MC2_155 ERLSKLSDEDLATLARALGPLERLAGQDEDKKNERETPKPAEQTS---- Rv0042c|M.tuberculosis_H37Rv ALLSQLPRSDLETLRKALAPLERLASGEPASGPASNSPARKRA------ Mb0043c|M.bovis_AF2122/97 ALLSQLPRSDLETLRKALAPLERLASGEPASGPASNSPARKRA------ MAV_0057|M.avium_104 AMLSQLPASDLDTLMKALAPLERLASGDPTSGPAGVPPARKEA------ MMAR_0059|M.marinum_M AMLDQLPHSDLETLMTALTPLERLACGEPANAPEDDAATPGRG------ MUL_0058|M.ulcerans_Agy99 AMLDQLPHSDLETLMTALTPLERLACGEPANAPEDDAATPGRG------ MLBr_02696|M.leprae_Br4923 TMLSQLPTSDLNILKNALAPLQRLASGEPVSSPAGDSPACKQA------ MAB_0157|M.abscessus_ATCC_1997 PWLSTLPAEEQRTLAEAAAILERLTRRMAAQSG---------------- TH_0729|M.thermoresistible__bu PYIDRLSDTDRAVLADAVRVMRQLLADAADPAVLPADPPSRPHESTELR :. *. : * * :.::